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cp 96345 and neurokinin a

cp 96345 has been researched along with neurokinin a in 72 studies

Research

Studies (72)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	70 (97.22)	18.2507
2000's	2 (2.78)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fong, TM; Strader, CD; Yu, H	1
Chrétien, L; Guillemette, G; Regoli, D; Tousignant, C	1
Dalsgaard, CJ; Maggi, CA; Wiesenfeld-Hallin, Z; Xu, XJ	1
Ellis, JL; Undem, BJ	1
Buckner, CK; Renzetti, LM; Shenvi, A	1
Kamiya, H; Nakayama, Y; Saito, R; Takano, Y; Tateishi, K	1
Advenier, C; Bakdach, H; Brelière, JC; Emonds-Alt, X; Le Fur, G; Naline, E; Toty, L; Vilain, P	1
Hill, JM; Kaufman, MP; Pickar, JG	1
Advenier, C; Emonds-Alt, X; Martin, CA; Naline, E	1
Yaksh, TL; Yamamoto, T	1
Ballati, L; Evangelista, S; Maggi, CA; Manzini, S	1
Appell, KC; Fragale, BJ; Loscig, J; Singh, S; Tomczuk, BE	1
Fujii, T; Kiyotoh, S; Maeda, Y; Morimoto, H; Murai, M; Nishikawa, M; Yamaoka, M	1
Alouan, LA; Armour, CL; Badgery-Parker, T; Black, JL; Burcher, E; Diment, LM; Johnson, PR	1
Dalsgaard, CJ; Wiesenfeld-Hallin, Z; Xu, XJ	1
Constantine, JW; Lebel, WS; Woody, HA	1
Broccardo, M; Improta, G; Severini, C	1
Beaujouan, JC; Glowinski, J; Petitet, F; Saffroy, M; Torrens, Y	1
Hay, DW; Hubbard, WC; Undem, BJ	1
Advenier, C; Hirsch, A; Martin, CA; Molimard, M; Naline, E	1
Joos, GF; Kips, JC; Pauwels, RA	1
Buéno, L; Julia, V; Morteau, O	1
Hill, RG; Longmore, J; Razzaque, Z; Shaw, D	1
Brugger, F; Evans, RH; Lepre, M; Olpe, HR	1
Gomi, Y; Mizuno, K; Suzuki, N	1
Lefebvre, RA; Smits, GJ	1
Ballati, L; Boni, P; Evangelista, S	1
Gether, U; Lowe, JA; Schwartz, TW	1
Luo, L; Wiesenfeld-Hallin, Z	2
Killingsworth, CR; Shore, SA	1
Dray, A; Maggi, CA; Nagy, I; Urban, L; Woolf, CJ	1
Boucher, S; Couture, R; Gitter, BD; Howbert, JJ; Picard, P; Regoli, D	1
Advenier, C; Emonds-Alt, X; Qian, Y	1
Giuliani, S; Maggi, CA; Meini, S; Patacchini, R	1
Iwata, T; Kamiya, H; Matsumoto, H; Ohno, M; Saito, R; Shimohigashi, Y; Takano, Y	1
Brelière, JC; Emonds-Alt, X; Gether, U; Lowe, JA; Nakanishi, S; Schwartz, TW; Snider, RM; Yokota, Y	1
Anding, P; Gao, XP; Lowe, J; Rennard, SI; Robbins, RA; Rubinstein, I; Snider, RM	1
Bertrand, C; Bunnett, NW; Debas, HT; Geppetti, P; Huber, O; Nadel, JA; Pellegrini, CA	1
Henry, JL	1
Jukic, D; Nguyen, QT; Regoli, D; Rouissi, N	1
Honda, K; Kamiya, H; Nakayama, Y; Saigo, A; Saito, R; Takano, Y	1
Cavero, I; Floch, A; Massa, N; Thiry, C	1
Giachetti, A; Giuliani, S; Maggi, CA; Patacchini, R	1
Couture, R; Culman, J; Picard, P; Prat, A; Regoli, D; Tschöpe, C; Unger, T	1
Bartho, L; Giuliani, S; Maggi, CA; Santicioli, P	1
Dray, A; Maggi, CA; Nagy, I; Urban, L	1
Boucher, S; Couture, R; Picard, P; Regoli, D	1
Hess, HJ; Kanai, Y; Lowe, JA; Nagahisa, A; Suga, O; Taniguchi, K; Tsuchiya, M	1
Bertrand, C; Geppetti, P; Graf, PD; Nadel, JA	1
Baugh, LE; Farrell, AM; Kudlacz, EM; Logan, DE; Shatzer, SA	1
Mizuguchi, T; Shimoyama, N; Yamamoto, T	1
Dougherty, PM; Palecek, J; Palecková, V; Willis, WD	1
Gertner, SB; Selig, WM; Tocker, JE; Welton, AF	1
Bannenberg, G; Kimland, M; Lundberg, JM; Moldéus, P; Ryrfeldt, A	1
Couture, R; Picard, P; Prat, A; Regoli, D	1
Bertrand, C; Bunnett, NW; Debas, HT; Geppetti, P; Huber, O; Nadel, JA; Nakazato, P; Pellegrini, CA	1
Buckner, CK; Campbell, J; Dea, D; Krell, RD; Lengel, D; Liberati, N; Miller, S; Shenvi, A; Stinson-Fisher, C	1
Bansal, A; Cascieri, MA; Fong, TM; Strader, CD; Swain, C; Yu, H	1
Doerfler, DL; Sailstad, DM; Selgrade, M; Veronesi, B	1
Gascón, P; Rameshwar, P	1
Chapman, RW; Danko, G; del Prado, M; Hey, JA	1
Back, SM; Hua, XY; Tam, EK	1
Henry, JL; Hui-Chan, CW; Yashpal, K	1
Fox, AJ; Naeem, S; Patel, IA; Urbán, L; Walpole, C	1
Henry, JL; Radhakrishnan, V	1
Holst, JJ; Rasmussen, TN; Schmidt, PT	1
Belmonte, KE; Costello, RW; Fryer, AD; Jacoby, DB	1
Kohno, S; Nabe, T; Ogawa, K; Yamamura, H	1
Inoue, M; Katsuyama, S; Kisara, K; Sakurada, C; Sakurada, S; Sakurada, T; Sasaki, J; Tan-No, K; Ueda, H	1
Ando, R; Kawamura, S; Sakurada, T; Watanabe, C; Yonezawa, A	1
Allescher, HD; Hahn, A; Storr, M	1

Reviews

2 review(s) available for cp 96345 and neurokinin a

Article	Year
Tachykinin non-peptide antagonists: binding domain and molecular mode of action. Biochemical Society transactions, 1995, Volume: 23, Issue:1 Topics: Animals; Benzamides; Binding Sites; Binding, Competitive; Biphenyl Compounds; GTP-Binding Proteins; Humans; Kinetics; Mutagenesis, Site-Directed; Neurokinin A; Piperidines; Point Mutation; Protein Structure, Secondary; Receptors, Tachykinin; Recombinant Fusion Proteins; Substance P; Tachykinins	1995
Participation of substance P in spinal physiological responses to peripheral aversive stimulation. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Animals; Biphenyl Compounds; Hypnotics and Sedatives; Neurokinin A; Neurons; Pain; Receptors, Neurokinin-2; Reflex; Spinal Cord; Substance P	1993

Article

Year

Tachykinin non-peptide antagonists: binding domain and molecular mode of action.

Biochemical Society transactions, 1995, Volume: 23, Issue:1

Topics: Animals; Benzamides; Binding Sites; Binding, Competitive; Biphenyl Compounds; GTP-Binding Proteins; Humans; Kinetics; Mutagenesis, Site-Directed; Neurokinin A; Piperidines; Point Mutation; Protein Structure, Secondary; Receptors, Tachykinin; Recombinant Fusion Proteins; Substance P; Tachykinins

1995

Participation of substance P in spinal physiological responses to peripheral aversive stimulation.

Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

Topics: Animals; Biphenyl Compounds; Hypnotics and Sedatives; Neurokinin A; Neurons; Pain; Receptors, Neurokinin-2; Reflex; Spinal Cord; Substance P

1993

Other Studies

70 other study(ies) available for cp 96345 and neurokinin a

Article	Year
Molecular basis for the species selectivity of the neurokinin-1 receptor antagonists CP-96,345 and RP67580. The Journal of biological chemistry, 1992, Dec-25, Volume: 267, Issue:36 Topics: Amino Acid Sequence; Animals; Binding Sites; Biphenyl Compounds; Cloning, Molecular; Humans; Indoles; Isoindoles; Kinetics; Mutagenesis, Site-Directed; Neurokinin A; Protein Conformation; Rats; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Recombinant Fusion Proteins; Recombinant Proteins; Substance P	1992
Characterization of NK-1 receptors in guinea pig and rat brain membranes with NK-1 peptides and a non-peptide antagonist. Brain research, 1992, Nov-20, Volume: 596, Issue:1-2 Topics: Amino Acid Sequence; Animals; Biphenyl Compounds; Brain; Guinea Pigs; Membranes; Molecular Sequence Data; Neurokinin A; Neurokinin B; Rats; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P	1992
NK-1, but not NK-2, tachykinin receptors mediate plasma extravasation induced by antidromic C-fiber stimulation in rat hindpaw: demonstrated with the NK-1 antagonist CP-96,345 and the NK-2 antagonist Men 10207. Neuroscience letters, 1992, May-25, Volume: 139, Issue:2 Topics: Animals; Biphenyl Compounds; Electric Stimulation; Female; Foot; Nerve Fibers; Neurokinin A; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Tachykinin	1992
Antigen-induced enhancement of noncholinergic contractile responses to vagus nerve and electrical field stimulation in guinea pig isolated trachea. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:2 Topics: Animals; Antigens; Biphenyl Compounds; Capsaicin; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Naloxone; Nerve Fibers; Neurokinin A; Peptide Fragments; Prostaglandin D2; Pyrilamine; Serotonin; Tetrodotoxin; Trachea; Vagus Nerve	1992
Nonadrenergic, noncholinergic contractile responses of the guinea pig hilar bronchus involve the preferential activation of tachykinin neurokinin2 receptors. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:3 Topics: Animals; Biphenyl Compounds; Bronchi; Culture Techniques; Electric Stimulation; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Receptors, Tachykinin	1992
Role of NK-1 receptor in central cardiovascular regulation in rats: studies on a novel non-peptide antagonist, CP-96,345, of substance P NK-1 receptor. Neuroscience letters, 1992, May-11, Volume: 139, Issue:1 Topics: Animals; Biphenyl Compounds; Blood Pressure; Hemodynamics; Injections, Intraventricular; Male; Neurokinin A; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Tachykinins	1992
Effects on the isolated human bronchus of SR 48968, a potent and selective nonpeptide antagonist of the neurokinin A (NK2) receptors. The American review of respiratory disease, 1992, Volume: 146, Issue:5 Pt 1 Topics: Acetylcholine; Amino Acid Sequence; Animals; Benzamides; Biphenyl Compounds; Bronchi; Bronchoconstriction; Cricetinae; Dinoprost; Dose-Response Relationship, Drug; Drug Antagonism; Drug Evaluation, Preclinical; Female; Histamine; Humans; In Vitro Techniques; Male; Middle Aged; Molecular Sequence Data; Neurokinin A; Peptide Fragments; Piperidines; Potassium Chloride; Racemases and Epimerases; Receptors, Neurokinin-2; Receptors, Neurotransmitter	1992
Attenuation of reflex pressor and ventilatory responses to static contraction by an NK-1 receptor antagonist. Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:4 Topics: Amino Acid Sequence; Animals; Biphenyl Compounds; Blood Pressure; Cats; Heart Rate; Injections, Spinal; Molecular Sequence Data; Myocardial Contraction; Neurokinin A; Neurokinin B; Physical Exertion; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Respiratory Mechanics; Spinal Cord; Synaptic Transmission; Tidal Volume	1992
Influence of (+/-)-CP-96,345 and SR 48968 on electrical field stimulation of the isolated guinea-pig main bronchus. European journal of pharmacology, 1992, Dec-02, Volume: 224, Issue:2-3 Topics: Animals; Benzamides; Biphenyl Compounds; Bronchi; Bronchoconstriction; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Neurokinin A; Piperidines; Receptors, Neurokinin-2; Receptors, Neurotransmitter	1992
Effects of intrathecal capsaicin and an NK-1 antagonist, CP,96-345, on the thermal hyperalgesia observed following unilateral constriction of the sciatic nerve in the rat. Pain, 1992, Volume: 51, Issue:3 Topics: Animals; Biphenyl Compounds; Capsaicin; Hot Temperature; Hypnotics and Sedatives; Injections, Spinal; Male; Neurokinin A; Neuropeptides; Nociceptors; Pain; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord	1992
Effects of selective tachykinin receptor antagonists on capsaicin- and tachykinin-induced bronchospasm in anaesthetized guinea-pigs. European journal of pharmacology, 1992, Apr-22, Volume: 214, Issue:2-3 Topics: Anesthesia; Animals; Atropine; Biphenyl Compounds; Bronchial Spasm; Capsaicin; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Male; Neurokinin A; Peptide Fragments; Receptors, Neurotransmitter; Receptors, Tachykinin; Tachykinins	1992
Antagonists that demonstrate species differences in neurokinin-1 receptors. Molecular pharmacology, 1992, Volume: 41, Issue:4 Topics: Amino Acid Sequence; Animals; Binding, Competitive; Biphenyl Compounds; Cell Line; Guinea Pigs; Humans; Molecular Sequence Data; Neurokinin A; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Species Specificity; Structure-Activity Relationship; Substance P	1992
FK 224, a novel cyclopeptide substance P antagonist with NK1 and NK2 receptor selectivity. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:1 Topics: Animals; Binding, Competitive; Biphenyl Compounds; Cell Membrane; Cerebral Cortex; Guinea Pigs; Lung; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptides, Cyclic; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P	1992
Tachykinin receptors in rabbit airways--characterization by functional, autoradiographic and binding studies. British journal of pharmacology, 1992, Volume: 107, Issue:2 Topics: Amino Acid Sequence; Animals; Autoradiography; Binding Sites; Biphenyl Compounds; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Rabbits; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins; Trachea	1992
Intrathecal CP-96,345 blocks reflex facilitation induced in rats by substance P and C-fiber-conditioning stimulation. European journal of pharmacology, 1992, Jun-17, Volume: 216, Issue:3 Topics: Analysis of Variance; Animals; Behavior, Animal; Biphenyl Compounds; Electric Stimulation; Injections, Spinal; Nerve Fibers; Neurokinin A; Rats; Rats, Sprague-Dawley; Reflex; Spinal Cord; Substance P; Sural Nerve	1992
Inhibition of tachykinin-induced hypotension in dogs by CP-96,345, a selective blocker of NK-1 receptors. Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 344, Issue:4 Topics: Animals; Biphenyl Compounds; Blood Pressure; Decerebrate State; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Neurokinin A; Peptide Fragments; Receptors, Neurotransmitter; Receptors, Tachykinin; Stereoisomerism; Substance P; Tachykinins	1991
Parallel bioassay of PG-SPI, an amphibian acidic SP-like peptide, mammalian basic substance P, and neurokinins A and B on in vitro and in vivo test systems. Peptides, 1995, Volume: 16, Issue:4 Topics: Amino Acid Sequence; Animals; Biological Assay; Biphenyl Compounds; Cricetinae; Evaluation Studies as Topic; Gastric Mucosa; Guinea Pigs; Injections, Intraventricular; Male; Molecular Sequence Data; Neurokinin A; Neurokinin B; Oligopeptides; Organ Culture Techniques; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rabbits; Ranidae; Rats; Rats, Wistar; Receptors, Tachykinin; Substance P	1995
A new selective bioassay for tachykinin NK3 receptors based on inositol monophosphate accumulation in the guinea pig ileum. European journal of pharmacology, 1993, Oct-15, Volume: 247, Issue:2 Topics: Animals; Biphenyl Compounds; Guinea Pigs; Hypnotics and Sedatives; Ileum; In Vitro Techniques; Inositol Phosphates; Male; Muscle, Smooth; Neurokinin A; Peptide Fragments; Phosphatidylinositols; Phospholipids; Receptors, Neurokinin-3; Stimulation, Chemical; Substance P; Tachykinins	1993
Relative contributions of direct and indirect mechanisms mediating endothelin-induced contraction of guinea-pig trachea. British journal of pharmacology, 1993, Volume: 110, Issue:3 Topics: Animals; Benzamides; Biphenyl Compounds; Capsaicin; Dicarboxylic Acids; Endothelins; Epithelium; Guinea Pigs; Histamine Release; In Vitro Techniques; Kinetics; Leukotriene Antagonists; Male; Muscle Contraction; Neurokinin A; Piperidines; Prostaglandins; Receptors, Tachykinin; SRS-A; Tetrodotoxin; Trachea	1993
Contractile effects of bradykinin on the isolated human small bronchus. American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:1 Topics: Acetylcholine; Aged; Atropine; Benzamides; Biphenyl Compounds; Bradykinin; Bronchi; Bronchoconstriction; Capsaicin; Humans; In Vitro Techniques; Indomethacin; Middle Aged; Muscle, Smooth; Nerve Fibers; Neurokinin A; Neurons, Afferent; Piperidines; Receptors, Bradykinin; Ruthenium Red; Tetrodotoxin	1994
In vivo characterization of the tachykinin receptors involved in the direct and indirect bronchoconstrictor effect of tachykinins in two inbred rat strains. American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:5 Topics: Airway Resistance; Animals; Atropine; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Captopril; Dose-Response Relationship, Drug; Indoles; Isoindoles; Male; Methysergide; Neurokinin A; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Tachykinin; Serotonin; Substance P; Thiorphan	1994
Involvement of neurokinin 1 and 2 receptors in viscerosensitive response to rectal distension in rats. Gastroenterology, 1994, Volume: 107, Issue:1 Topics: Abdomen; Animals; Benzamides; Biphenyl Compounds; Colon; Colonic Diseases, Functional; Gastrointestinal Motility; Hypnotics and Sedatives; Indoles; Isoindoles; Male; Neurokinin A; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Rectum; Substance P; Tachykinins	1994
Differences in the effects of NK1-receptor antagonists, (+/-)-CP 96,345 and CP 99,994, on agonist-induced responses in guinea-pig trachea. British journal of pharmacology, 1994, Volume: 112, Issue:1 Topics: Animals; Biphenyl Compounds; Guinea Pigs; In Vitro Techniques; Indoles; Isoindoles; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Pyrrolidonecarboxylic Acid; Substance P; Trachea	1994
Physiological and pharmacological characterization of the spinal tachykinin NK2 receptor. European journal of pharmacology, 1994, Jun-02, Volume: 258, Issue:1-2 Topics: Animals; Animals, Newborn; Biphenyl Compounds; Dose-Response Relationship, Drug; Drug Interactions; Ganglia, Spinal; Gerbillinae; Hypnotics and Sedatives; In Vitro Techniques; Indoles; Isoindoles; Neurokinin A; Oligopeptides; Peptide Fragments; Rats; Receptors, Neurokinin-2; Spinal Cord; Substance P; Tetrodotoxin	1994
Tachykinin-induced contractions in the circular muscle of guinea pig ileum. Japanese journal of pharmacology, 1994, Volume: 65, Issue:3 Topics: Animals; Atropine; Biphenyl Compounds; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Hypnotics and Sedatives; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptides, Cyclic; Rats; Structure-Activity Relationship; Substance P; Tachykinins; Tetrodotoxin	1994
Tachykinin receptors involved in the contractile effect of the natural tachykinins in the rat gastric fundus. Journal of autonomic pharmacology, 1994, Volume: 14, Issue:6 Topics: Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Gastric Fundus; Indoles; Isoindoles; Male; Methacholine Chloride; Muscle Contraction; Neurokinin A; Neurokinin B; Peptide Fragments; Peptides, Cyclic; Rats; Receptors, Tachykinin; Substance P; Tachykinins	1994
Tachykinin NK1 and NK2 receptors mediate the non-cholinergic bronchospastic response to capsaicin and vagal stimulation in guinea-pigs. Journal of autonomic pharmacology, 1995, Volume: 15, Issue:1 Topics: Animals; Biphenyl Compounds; Bronchial Spasm; Capsaicin; Electric Stimulation; Guinea Pigs; Insufflation; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Peptides, Cyclic; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Vagus Nerve	1995
The effects of pretreatment with tachykinin antagonists and galanin on the development of spinal cord hyperexcitability following sciatic nerve section in the rat. Neuropeptides, 1995, Volume: 28, Issue:3 Topics: Afferent Pathways; Animals; Biphenyl Compounds; Causalgia; Electric Stimulation; Female; Galanin; Hypesthesia; Injections, Spinal; Neurokinin A; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Reflex, Abnormal; Sciatic Nerve; Spinal Cord; Tachykinins	1995
Tachykinin receptors mediating contraction of guinea pig lung strips. Regulatory peptides, 1995, May-30, Volume: 57, Issue:2 Topics: Acetylcholine; Animals; Benzamides; Biphenyl Compounds; Dipeptides; Guinea Pigs; In Vitro Techniques; Lung; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P; Trachea	1995
The role of neurokinin and N-methyl-D-aspartate receptors in synaptic transmission from capsaicin-sensitive primary afferents in the rat spinal cord in vitro. Neuroscience, 1993, Volume: 52, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Biphenyl Compounds; Capsaicin; Ganglia, Spinal; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurokinin A; Neurons; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Spinal Cord; Substance P; Synapses; Synaptic Transmission	1993
Use of non-peptide tachykinin receptor antagonists to substantiate the involvement of NK1 and NK2 receptors in a spinal nociceptive reflex in the rat. European journal of pharmacology, 1993, Mar-02, Volume: 232, Issue:2-3 Topics: Animals; Benzamides; Biphenyl Compounds; Hypnotics and Sedatives; Injections, Spinal; Male; Neurokinin A; Nociceptors; Pain Measurement; Pain Threshold; Peptide Fragments; Piperidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Receptors, Tachykinin; Reflex; Spinal Cord; Substance P	1993
Effects of capsaicin, (+/-)-CP-96,345 and SR 48968 on the bradykinin-induced airways microvascular leakage in guinea-pigs. Pulmonary pharmacology, 1993, Volume: 6, Issue:1 Topics: Animals; Autonomic Nervous System; Benzamides; Biphenyl Compounds; Bradykinin; Capillary Permeability; Capsaicin; Evans Blue; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Nerve Endings; Neurokinin A; Piperidines; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P	1993
Evidence for the presence of a septide-sensitive tachykinin receptor in the circular muscle of the guinea-pig ileum. European journal of pharmacology, 1993, Apr-28, Volume: 235, Issue:2-3 Topics: Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscles; Neurokinin A; Peptide Fragments; Pyrrolidonecarboxylic Acid; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins	1993
Receptor-mediated specific biological activity of a beta-amyloid protein fragment for NK-1 substance P receptors. Biochemical and biophysical research communications, 1993, Jun-15, Volume: 193, Issue:2 Topics: Amino Acid Sequence; Amyloid beta-Peptides; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P	1993
Low-dose intrathecal clonidine releases tachykinins in rat spinal cord. European journal of pharmacology, 1993, Apr-22, Volume: 235, Issue:1 Topics: Animals; Biphenyl Compounds; Clonidine; Decerebrate State; Hypnotics and Sedatives; Injections, Spinal; Neurokinin A; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reflex; Spinal Cord; Substance P	1993
Two nonpeptide tachykinin antagonists act through epitopes on corresponding segments of the NK1 and NK2 receptors. Proceedings of the National Academy of Sciences of the United States of America, 1993, Jul-01, Volume: 90, Issue:13 Topics: Animals; Benzamides; Binding Sites; Biphenyl Compounds; Cells, Cultured; Epitopes; Neurokinin A; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P	1993
NK1 receptors mediate tachykinin-induced increase in microvascular clearance in hamster cheek pouch. The American journal of physiology, 1993, Volume: 265, Issue:2 Pt 2 Topics: Animals; Biphenyl Compounds; Capsaicin; Cheek; Cricetinae; Macromolecular Substances; Male; Mesocricetus; Microcirculation; Neurokinin A; Neurokinin B; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Tachykinins	1993
Tachykinins contract the circular muscle of the human esophageal body in vitro via NK2 receptors. Gastroenterology, 1993, Volume: 105, Issue:4 Topics: Adolescent; Adult; Aged; Atropine; Benzamides; Biphenyl Compounds; Carbachol; Dose-Response Relationship, Drug; Esophagus; Glycopeptides; Humans; Isometric Contraction; Middle Aged; Muscle Contraction; Muscle, Smooth; Neprilysin; Neurokinin A; Neurokinin B; Piperidines; Receptors, Tachykinin; Substance P; Tachykinins; Tetrodotoxin	1993
Functional characterization of neurokinin receptors with agonists and antagonists. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Amino Acid Sequence; Animals; Biphenyl Compounds; Guinea Pigs; Molecular Sequence Data; Muscle, Smooth; Muscle, Smooth, Vascular; Neurokinin A; Neurokinin B; Portal Vein; Rabbits; Rats; Receptors, Tachykinin; Structure-Activity Relationship; Substance P; Tachykinins; Trachea; Venae Cavae	1993
Role of NK-1 receptor in central cardiovascular regulation in rats: studies on a novel non-peptide antagonist, CP-96,345, of substance P NK-1 receptor. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Animals; Biphenyl Compounds; Blood Pressure; Cerebral Ventricles; Heart Rate; Hypnotics and Sedatives; Injections, Intraventricular; Male; Muscle Contraction; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Rats; Receptors, Neurokinin-1; Substance P; Tachykinins; Vas Deferens	1993
Evidence for NK-1 receptor subtypes from in vivo bronchopulmonary and cardiovascular studies. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Animals; Biphenyl Compounds; Blood Pressure; Bronchi; Bronchoconstriction; Guinea Pigs; Indoles; Isoindoles; Lung; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P	1993
In vivo and in vitro activity of SR 48,968, a non-peptide tachykinin NK-2 receptor antagonist. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Animals; Benzamides; Biphenyl Compounds; Blood Pressure; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Piperidines; Rats; Receptors, Neurokinin-2; Saliva; Substance P; Sulfones; Urinary Bladder	1993
In vivo characterization of tachykinin receptors responsible for the central cardiovascular effects of substance P and neurokinin A. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Animals; Behavior, Animal; Biphenyl Compounds; Blood Pressure; Heart Rate; Neurokinin A; Oligopeptides; Peptide Fragments; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Stereotyped Behavior; Substance P	1993
Tachykinin NK-1 and NK-2 receptors in the circular muscle of the guinea-pig proximal colon. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Animals; Benzamides; Biphenyl Compounds; Colon; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Peptides, Cyclic; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Sulfones; Tetrodotoxin	1993
The effects of NK-1 and NK-2 receptor antagonists on the capsaicin evoked synaptic response in the rat spinal cord in vitro. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Animals; Biphenyl Compounds; Capsaicin; In Vitro Techniques; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Spinal Cord; Substance P; Synapses	1993
Receptor characterization of the spinal action of neurokinins on nociception: a three receptor hypothesis. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Animals; Benzamides; Biphenyl Compounds; Models, Neurological; Neurokinin A; Neurokinin-1 Receptor Antagonists; Oligopeptides; Pain; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Neurotransmitter; Spinal Cord; Substance P	1993
Antiinflammatory and analgesic activity of CP-96,345: an orally active non-peptide substance P receptor antagonist. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bradykinin; Dose-Response Relationship, Drug; Evans Blue; Guinea Pigs; Histamine; Leukotriene D4; Male; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Platelet Activating Factor; Receptors, Neurokinin-1; Skin; Substance P; Ureter	1993
Capsaicin increases airflow resistance in guinea pigs in vivo by activating both NK2 and NK1 tachykinin receptors. The American review of respiratory disease, 1993, Volume: 148, Issue:4 Pt 1 Topics: Airway Resistance; Animals; Atropine; Benzamides; Biphenyl Compounds; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Histamine; Male; Neurokinin A; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P	1993
Tachykinin-mediated respiratory effects in conscious guinea pigs: modulation by NK1 and NK2 receptor antagonists. European journal of pharmacology, 1993, Sep-07, Volume: 241, Issue:1 Topics: Aerosols; Animals; Biphenyl Compounds; Capsaicin; Cell Membrane; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neuropeptides; Receptors, Neurokinin-2; Respiration; Substance P; Tachykinins	1993
Effects of FK224, a novel cyclopeptide NK1 and NK2 antagonist, and CP-96,345, a nonpeptide NK1 antagonist, on development and maintenance of thermal hyperesthesia evoked by carrageenan injection in the rat paw. Anesthesiology, 1993, Volume: 79, Issue:5 Topics: Animals; Biphenyl Compounds; Carrageenan; Extremities; Hot Temperature; Hyperesthesia; Male; Neurokinin A; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Substance P	1993
Neurokinin 1 and 2 antagonists attenuate the responses and NK1 antagonists prevent the sensitization of primate spinothalamic tract neurons after intradermal capsaicin. Journal of neurophysiology, 1994, Volume: 72, Issue:4 Topics: Animals; Biphenyl Compounds; Capsaicin; Female; Ganglia, Spinal; Injections, Intradermal; Macaca fascicularis; Male; Mechanoreceptors; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neurons; Nociceptors; Pain Threshold; Peptide Fragments; Physalaemin; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Skin; Spinothalamic Tracts; Synaptic Transmission	1994
Vagal stimulation augments pulmonary anaphylaxis in the guinea pig lung. American journal of respiratory and critical care medicine, 1995, Volume: 151, Issue:2 Pt 1 Topics: Anaphylaxis; Animals; Atropine; Benzamides; Biphenyl Compounds; Bronchoconstriction; Electric Stimulation; Guinea Pigs; Hypnotics and Sedatives; Lung; Male; Neurokinin A; Organ Size; Physostigmine; Piperidines; Trachea; Vagus Nerve; Vasoconstriction	1995
Sensory neuropeptide-mediated bronchoconstriction of the guinea pig lung by diamide; a comparison to hydrogen peroxide. European journal of pharmacology, 1994, Apr-04, Volume: 270, Issue:2-3 Topics: Animals; Benzamides; Biphenyl Compounds; Bronchoconstriction; Calcitonin Gene-Related Peptide; Capsaicin; Carbazoles; Diamide; Guinea Pigs; Hydrogen Peroxide; In Vitro Techniques; Lung; Male; Neurokinin A; Neurons, Afferent; Neuropeptides; Piperidines; Thromboxanes	1994
Characterization of the cardiovascular and behavioral effects of centrally administered neuropeptide K in the conscious rat. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Amino Acid Sequence; Animals; Benzamides; Biphenyl Compounds; Blood Pressure; Cerebral Ventricles; Fenclonine; Heart Rate; Injections, Intraventricular; Male; Molecular Sequence Data; Motor Activity; Neurokinin A; Neuropeptides; Oligopeptides; Piperidines; Rats; Rats, Wistar; Stereotyped Behavior; Tachykinins	1993
Tachykinins mediate contraction of the human lower esophageal sphincter in vitro via activation of NK2 receptors. European journal of pharmacology, 1993, Aug-03, Volume: 239, Issue:1-3 Topics: Benzamides; Biphenyl Compounds; Dose-Response Relationship, Drug; Esophagogastric Junction; Glycopeptides; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neprilysin; Neurokinin A; Neurokinin B; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Tachykinins	1993
Differential blockade by tachykinin NK1 and NK2 receptor antagonists of bronchoconstriction induced by direct-acting agonists and the indirect-acting mimetics capsaicin, serotonin and 2-methyl-serotonin in the anesthetized guinea pig. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3 Topics: Amino Acid Sequence; Anesthesia; Animals; Benzamides; Biphenyl Compounds; Bronchial Spasm; Bronchoconstriction; Capsaicin; Guinea Pigs; Hypnotics and Sedatives; Injections, Intravenous; Male; Molecular Sequence Data; Neurokinin A; Piperidines; Receptors, Tachykinin; Serotonin	1993
Amino-aromatic interaction between histidine 197 of the neurokinin-1 receptor and CP 96345. Nature, 1993, Mar-25, Volume: 362, Issue:6418 Topics: Amino Acid Sequence; Biphenyl Compounds; Histidine; Humans; Hypnotics and Sedatives; Molecular Sequence Data; Neurokinin A; Point Mutation; Receptors, Neurokinin-2; Receptors, Neurotransmitter	1993
Neuropeptide modulation of chemically induced skin irritation. Toxicology and applied pharmacology, 1995, Volume: 135, Issue:2 Topics: Administration, Cutaneous; Animals; Benzamides; Biphenyl Compounds; Capsaicin; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Dose-Response Relationship, Drug; Ear, External; Female; Irritants; Mice; Mice, Inbred BALB C; Neurokinin A; Neuropeptides; Piperidines; Skin; Substance P; Synaptic Transmission	1995
Induction of negative hematopoietic regulators by neurokinin-A in bone marrow stroma. Blood, 1996, Jul-01, Volume: 88, Issue:1 Topics: Amino Acid Sequence; Benzamides; Biphenyl Compounds; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Chemokine CCL4; Connective Tissue; Depression, Chemical; Erythroid Precursor Cells; Hematopoietic Stem Cells; Humans; Macrophage Inflammatory Proteins; Molecular Sequence Data; Monokines; Neurokinin A; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Transforming Growth Factor beta	1996
Augmentation of neurally evoked cholinergic bronchoconstrictor responses by prejunctional NK2 receptors in the guinea-pig. Journal of autonomic pharmacology, 1996, Volume: 16, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Biphenyl Compounds; Bronchoconstriction; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Male; Medulla Oblongata; Methacholine Chloride; Muscle, Smooth; Neurokinin A; Neurokinin B; Piperidines; Substance P	1996
Substance P enhances electrical field stimulation-induced mast cell degranulation in rat trachea. The American journal of physiology, 1996, Volume: 270, Issue:6 Pt 1 Topics: Animals; Biphenyl Compounds; Capsaicin; Cell Degranulation; Chymotrypsin; Dose-Response Relationship, Drug; Electric Stimulation; Indomethacin; Male; Mast Cells; Neurokinin A; Neurokinin-1 Receptor Antagonists; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Substance P; Trachea	1996
SR 48968 specifically depresses neurokinin A- vs. substance P-induced hyperalgesia in a nociceptive withdrawal reflex. European journal of pharmacology, 1996, Jul-11, Volume: 308, Issue:1 Topics: Animals; Benzamides; Biphenyl Compounds; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Spinal; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Pain Measurement; Pain Threshold; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P	1996
Receptors mediating tachykinin-evoked depolarisations of neurons in the neonatal rat spinal cord. Acta biologica Hungarica, 1996, Volume: 47, Issue:1-4 Topics: Animals; Animals, Newborn; Biphenyl Compounds; Evoked Potentials; In Vitro Techniques; Indoles; Isoindoles; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neurons; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Spinal Cord; Substance P; Tachykinins	1996
Electrophysiological evidence that neurokinin A acts via NK-1 receptors in the cat dorsal horn. The European journal of neuroscience, 1997, Volume: 9, Issue:9 Topics: Animals; Benzamides; Biphenyl Compounds; Cats; Iontophoresis; Neurokinin A; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Spinal Cord; Stereoisomerism; Substance P; Synapses	1997
Tachykinins may mediate capsaicin-induced, but not vagally induced motility in porcine antrum. Peptides, 1997, Volume: 18, Issue:10 Topics: Animals; Benzamides; Biphenyl Compounds; Capsaicin; Electric Stimulation; Gastrointestinal Motility; Muscle Contraction; Neurokinin A; Neurokinin-1 Receptor Antagonists; Piperidines; Pyloric Antrum; Receptors, Neurokinin-2; Substance P; Swine; Tachykinins; Vagus Nerve	1997
Effects of tachykinin NK1 receptor antagonists on vagal hyperreactivity and neuronal M2 muscarinic receptor function in antigen challenged guinea-pigs. British journal of pharmacology, 1998, Volume: 124, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Electric Stimulation; Eosinophilia; Guinea Pigs; Lung; Neurokinin A; Neurokinin-1 Receptor Antagonists; Ovalbumin; Peptide Fragments; Pilocarpine; Piperidines; Quinuclidines; Receptor, Muscarinic M2; Receptors, Muscarinic; Receptors, Tachykinin; Specific Pathogen-Free Organisms; Substance P; Trachea; Vagus Nerve	1998
Nanomolar concentrations of neuropeptides induce histamine release from peritoneal mast cells of a substrain of Wistar rats. European journal of pharmacology, 1999, Jun-18, Volume: 374, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Biphenyl Compounds; Dose-Response Relationship, Drug; Histamine Release; Male; Mast Cells; Neurokinin A; Peritoneum; Piperidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity; Substance P; Tachykinins	1999
Nociceptin-induced scratching, biting and licking in mice: involvement of spinal NK1 receptors. British journal of pharmacology, 1999, Volume: 127, Issue:7 Topics: Aggression; Analgesics, Opioid; Animals; Antibodies, Blocking; Behavior, Animal; Biphenyl Compounds; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mice; Morphine; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neurons; Nociceptin; Opioid Peptides; Piperidines; Receptors, Neurokinin-1; Receptors, Opioid; Spinal Cord; Substance P	1999
Involvement of spinal NK2 and NMDA receptors in aversive behavior induced by intra-arterial injection of capsaicin. Pharmacology, biochemistry, and behavior, 2001, Volume: 68, Issue:1 Topics: Animals; Avoidance Learning; Biphenyl Compounds; Capsaicin; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Femoral Artery; Guinea Pigs; Hindlimb; Injections, Intra-Arterial; Male; Neurokinin A; Nociceptors; Pain; Peptide Fragments; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-2; Spinal Cord; Vocalization, Animal	2001
Effect of tachykinins on ascending and descending reflex pathway in rat small intestine. Acta pharmacologica Sinica, 2002, Volume: 23, Issue:4 Topics: Afferent Pathways; Animals; Biphenyl Compounds; Efferent Pathways; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Physalaemin; Rats; Rats, Wistar; Reaction Time; Receptors, Neurokinin-2; Reflex; Substance P; Tachykinins	2002