Page last updated: 2024-09-03

cp 93129 and 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole

cp 93129 has been researched along with 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole in 8 studies

Compound Research Comparison

Studies
(cp 93129)
Trials
(cp 93129)
Recent Studies (post-2010)
(cp 93129)
Studies
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Trials
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Recent Studies (post-2010) (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
109011218012

Protein Interaction Comparison

ProteinTaxonomycp 93129 (IC50)5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50)
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)5.4
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)5.4
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0107
5-hydroxytryptamine receptor 1DHomo sapiens (human)0.039
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.295
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.004
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)5.4
5-hydroxytryptamine receptor 6Homo sapiens (human)0.079

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (75.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burkhart, CA; Heym, JH; Ives, JL; Lebel, LA; Macor, JE; Newman, ME; Nielsen, JA; Ryan, K; Schulz, DW; Torgersen, LK1
Hjorth, S; Tao, R1
Auerbach, SB; Hjorth, S1
Koob, GF; Parsons, LH; Weiss, F1
Fletcher, PJ; Korth, KM1
Bakker, MH; Bonaventure, P; Cras, P; Langlois, X; Leysen, JE; Luyten, WH; Megens, AA; Serneels, L; Umans, L; Van Leuven, F1
Yan, QS; Yan, SE1
Geyer, MA; Martinez-Price, DL1

Other Studies

8 other study(ies) available for cp 93129 and 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole

ArticleYear
3-(1,2,5,6-Tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one: a potent and selective serotonin (5-HT1B) agonist and rotationally restricted phenolic analogue of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:8

    Topics: Adenylyl Cyclase Inhibitors; Animals; Chemical Phenomena; Chemistry; Colforsin; Cyclization; Eating; Guinea Pigs; Hippocampus; Indoles; Molecular Structure; Paraventricular Hypothalamic Nucleus; Pyridines; Pyrroles; Rats; Receptors, Serotonin; Serotonin; Substantia Nigra

1990
The putative 5-HT1B receptor agonist CP-93,129 suppresses rat hippocampal 5-HT release in vivo: comparison with RU 24969.
    European journal of pharmacology, 1991, Dec-17, Volume: 209, Issue:3

    Topics: Animals; Brain Chemistry; Citalopram; Dialysis; Hippocampus; Indoles; Male; Methiothepin; Pyridines; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin

1991
Effect of chronic administration of the selective serotonin (5-HT) uptake inhibitor citalopram on extracellular 5-HT and apparent autoreceptor sensitivity in rat forebrain in vivo.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:6

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Autoreceptors; Citalopram; Dialysis; Drug Tolerance; Indoles; Infusions, Intravenous; Male; Prosencephalon; Pyridines; Pyrroles; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists

1995
Serotonin1B receptor stimulation enhances cocaine reinforcement.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Dec-01, Volume: 18, Issue:23

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Indoles; Injections, Intraventricular; Male; Oxadiazoles; Piperazines; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists

1998
Activation of 5-HT1B receptors in the nucleus accumbens reduces amphetamine-induced enhancement of responding for conditioned reward.
    Psychopharmacology, 1999, Volume: 142, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Conditioning, Psychological; Indoles; Male; Nucleus Accumbens; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Reward; Serotonin; Serotonin Receptor Agonists; Water

1999
Humanization of mouse 5-hydroxytryptamine1B receptor gene by homologous recombination: in vitro and in vivo characterization.
    Molecular pharmacology, 1999, Volume: 56, Issue:1

    Topics: Animals; Benzamides; Benzopyrans; Binding Sites; Brain; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hypothermia; In Situ Hybridization; Indoles; Mice; Mice, Transgenic; Motor Activity; Piperidones; Propylamines; Pyridines; Pyrimidines; Pyrroles; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Recombination, Genetic; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Tritium

1999
Serotonin-1B receptor-mediated inhibition of [(3)H]GABA release from rat ventral tegmental area slices.
    Journal of neurochemistry, 2001, Volume: 79, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzamides; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Indoles; Male; Oxadiazoles; Pindolol; Piperazines; Potassium; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Ventral Tegmental Area

2001
Subthalamic 5-HT(1A) and 5-HT(1B) receptor modulation of RU 24969-induced behavioral profile in rats.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 71, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Drug Interactions; Exploratory Behavior; Indoles; Male; Microinjections; Motor Activity; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Substantia Nigra; Subthalamus

2002