cp 115953 has been researched along with ellipticine in 1 studies
| Studies (cp 115953) | Trials (cp 115953) | Recent Studies (post-2010) (cp 115953) | Studies (ellipticine) | Trials (ellipticine) | Recent Studies (post-2010) (ellipticine) |
|---|---|---|---|---|---|
| 20 | 0 | 0 | 454 | 0 | 178 |
| Protein | Taxonomy | cp 115953 (IC50) | ellipticine (IC50) |
|---|---|---|---|
| Cytochrome P450 1A1 | Homo sapiens (human) | 0.0193 | |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | 0.2 | |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | 3.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elsea, SH; Hsiung, Y; Nitiss, JL; Osheroff, N | 1 |
1 other study(ies) available for cp 115953 and ellipticine
| Article | Year |
|---|---|
A yeast type II topoisomerase selected for resistance to quinolones. Mutation of histidine 1012 to tyrosine confers resistance to nonintercalative drugs but hypersensitivity to ellipticine.
Topics: Amino Acid Sequence; Animals; Anti-Infective Agents; DNA Topoisomerases, Type II; Drug Resistance; Ellipticines; Fluoroquinolones; Histidine; Humans; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Quinolones; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Topoisomerase II Inhibitors; Tyrosine | 1995 |