cp 100356 has been researched along with quinidine in 2 studies
Studies (cp 100356) | Trials (cp 100356) | Recent Studies (post-2010) (cp 100356) | Studies (quinidine) | Trials (quinidine) | Recent Studies (post-2010) (quinidine) |
---|---|---|---|---|---|
8 | 0 | 3 | 6,608 | 387 | 594 |
Protein | Taxonomy | cp 100356 (IC50) | quinidine (IC50) |
---|---|---|---|
Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | 6.4 | |
Cholinesterase | Homo sapiens (human) | 1.23 | |
ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 10 | |
ATP-dependent translocase ABCB1 | Homo sapiens (human) | 3.32 | |
Cytochrome P450 2D26 | Rattus norvegicus (Norway rat) | 2.8 | |
Cytochrome P450 2D6 | Homo sapiens (human) | 0.3532 | |
Potassium voltage-gated channel subfamily A member 5 | Homo sapiens (human) | 7.3 | |
Cholinesterase | Equus caballus (horse) | 7.37 | |
Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | 6.4 | |
Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.7882 | |
Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | 6.4 | |
Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | 6.4 | |
Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | 6.9 | |
Potassium voltage-gated channel subfamily D member 2 | Rattus norvegicus (Norway rat) | 2.2 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
de Graaf, IA; de Jager, MH; Groothuis, GM; Li, M | 1 |
de Graaf, IA; de Jager, MH; Groothuis, GM; Li, M; van de Steeg, E | 1 |
2 other study(ies) available for cp 100356 and quinidine
Article | Year |
---|---|
Rat precision-cut intestinal slices to study P-gp activity and the potency of its inhibitors ex vivo.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cyclosporins; In Vitro Techniques; Intestinal Mucosa; Isoquinolines; Ketoconazole; Male; Quinazolines; Quinidine; Rats, Wistar; Rhodamine 123; Verapamil | 2015 |
The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo.
Topics: Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colon; Cyclosporins; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Humans; Ileum; In Vitro Techniques; Isoquinolines; Jejunum; Ketoconazole; Male; Middle Aged; Quinazolines; Quinidine; Verapamil | 2017 |