Page last updated: 2024-09-05

cp 100356 and quinidine

cp 100356 has been researched along with quinidine in 2 studies

Compound Research Comparison

Studies (cp 100356)	Trials (cp 100356)	Recent Studies (post-2010) (cp 100356)	Studies (quinidine)	Trials (quinidine)	Recent Studies (post-2010) (quinidine)
8	0	3	6,608	387	594

Protein Interaction Comparison

Protein	Taxonomy	quinidine (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)	6.4
Cholinesterase	Homo sapiens (human)	1.23
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	10
ATP-dependent translocase ABCB1	Homo sapiens (human)	3.32
Cytochrome P450 2D26	Rattus norvegicus (Norway rat)	2.8
Cytochrome P450 2D6	Homo sapiens (human)	0.3532
Potassium voltage-gated channel subfamily A member 5	Homo sapiens (human)	7.3
Cholinesterase	Equus caballus (horse)	7.37
Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)	6.4
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	0.7882
Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)	6.4
Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)	6.4
Sodium channel protein type 5 subunit alpha	Homo sapiens (human)	6.9
Potassium voltage-gated channel subfamily D member 2	Rattus norvegicus (Norway rat)	2.2

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
de Graaf, IA; de Jager, MH; Groothuis, GM; Li, M	1
de Graaf, IA; de Jager, MH; Groothuis, GM; Li, M; van de Steeg, E	1

Other Studies

2 other study(ies) available for cp 100356 and quinidine

Article	Year
Rat precision-cut intestinal slices to study P-gp activity and the potency of its inhibitors ex vivo. Toxicology in vitro : an international journal published in association with BIBRA, 2015, Volume: 29, Issue:5 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cyclosporins; In Vitro Techniques; Intestinal Mucosa; Isoquinolines; Ketoconazole; Male; Quinazolines; Quinidine; Rats, Wistar; Rhodamine 123; Verapamil	2015
The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo. Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 40 Topics: Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colon; Cyclosporins; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Humans; Ileum; In Vitro Techniques; Isoquinolines; Jejunum; Ketoconazole; Male; Middle Aged; Quinazolines; Quinidine; Verapamil	2017

Article

Year

Rat precision-cut intestinal slices to study P-gp activity and the potency of its inhibitors ex vivo.

Toxicology in vitro : an international journal published in association with BIBRA, 2015, Volume: 29, Issue:5

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cyclosporins; In Vitro Techniques; Intestinal Mucosa; Isoquinolines; Ketoconazole; Male; Quinazolines; Quinidine; Rats, Wistar; Rhodamine 123; Verapamil

2015

The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo.

Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 40

Topics: Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colon; Cyclosporins; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Humans; Ileum; In Vitro Techniques; Isoquinolines; Jejunum; Ketoconazole; Male; Middle Aged; Quinazolines; Quinidine; Verapamil

2017