cox 189 has been researched along with flurbiprofen in 4 studies
| Studies (cox 189) | Trials (cox 189) | Recent Studies (post-2010) (cox 189) | Studies (flurbiprofen) | Trials (flurbiprofen) | Recent Studies (post-2010) (flurbiprofen) |
|---|---|---|---|---|---|
| 163 | 49 | 47 | 2,072 | 466 | 575 |
| Protein | Taxonomy | cox 189 (IC50) | flurbiprofen (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.1683 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.6754 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.574 | |
| Aldo-keto reductase family 1 member C3 | Homo sapiens (human) | 1.56 | |
| Prostaglandin G/H synthase 2 | Mus musculus (house mouse) | 0.5 | |
| Solute carrier family 22 member 6 | Homo sapiens (human) | 1.5 | |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | 0.17 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blobaum, AL; Marnett, LJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
2 review(s) available for cox 189 and flurbiprofen
| Article | Year |
|---|---|
Structural and functional basis of cyclooxygenase inhibition.
Topics: Animals; Cardiovascular System; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; History, 18th Century; History, 19th Century; History, 20th Century; History, 21st Century; History, Ancient; Humans; Kinetics; Models, Molecular; Protein Conformation; Risk Assessment | 2007 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 other study(ies) available for cox 189 and flurbiprofen
| Article | Year |
|---|---|
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |