Compounds > coumarin

coumarin and tegafur

coumarin has been researched along with tegafur in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Kaniwa, N; Murayama, N; Nakajima, Y; Ohno, Y; Ozawa, S; Sai, K; Sawada , J1
Ariyoshi, N; Daigo, S; Fujieda, M; Ikeda, K; Kamataki, T; Koizumi, W; Nagayama, S; Nishioka, Y; Saigenji, K; Takahashi, Y; Tanabe, S; Yamazaki, H1
Chiba, M; Ishii, Y; Yamada, H; Yamamiya, I; Yoshisue, K1

Other Studies

4 other study(ies) available for coumarin and tegafur

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Expression of CYP2A6 in tumor cells augments cellular sensitivity to tegafur.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:5

    Topics: Antimetabolites, Antineoplastic; Aryl Hydrocarbon Hydroxylases; Cell Division; Colonic Neoplasms; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Fluorouracil; Gene Expression; Humans; Hydroxylation; Microsomes; Mixed Function Oxygenases; Tegafur; Transfection; Tumor Cells, Cultured

2001
A novel mutant allele of the CYP2A6 gene (CYP2A6*11 ) found in a cancer patient who showed poor metabolic phenotype towards tegafur.
    Pharmacogenetics, 2002, Volume: 12, Issue:4

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2A6; DNA Primers; DNA, Neoplasm; Drug Combinations; Escherichia coli; Genotype; Humans; Kinetics; Middle Aged; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Oxonic Acid; Polymerase Chain Reaction; Polymorphism, Genetic; Pyridines; Recombinant Proteins; Stomach Neoplasms; Tegafur; Transfection

2002
Effect of CYP2A6 genetic polymorphism on the metabolic conversion of tegafur to 5-fluorouracil and its enantioselectivity.
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:9

    Topics: Cell Line; Coumarins; Cytochrome P-450 CYP2A6; DNA, Complementary; Escherichia coli; Fluorouracil; Humans; Microsomes, Liver; Nicotine; Polymorphism, Genetic; Sf9 Cells; Tegafur

2014