coumarin and rutin

coumarin has been researched along with rutin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19904 (22.22)18.7374
1990's3 (16.67)18.2507
2000's6 (33.33)29.6817
2010's4 (22.22)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Bohlin, L; Huss, U; Perera, P; Ringbom, T; Vasänge, M1
Burgueño-Tapia, E; Cornejo-Garrido, J; Domínguez-Mendoza, EA; Ordaz-Pichardo, C1
Calil, FA; Chibli, LA; Da Costa, FB; Nonato, MC; Schmidt, TJ1
Casley-Smith, JR1
Dedieu, F; Duverger, JP; Laemmel, E; Leutenegger, E; Pons, C; Stücker, O1
al-Nawas, B; Belz, GG; Bockisch, A; Grötz, KA; Henneicke-von Zepelin, HH; Kohnen, R; Kutzner, J; Naser-Hijazi, B; Wagner, W; Wüstenberg, P1
Clement, DL1
Burian, M; Freudenstein, J; Henneicke-von Zepelin, HH; Legrum, W; Naser-Hijazi, B; Tegtmeier, M1
Becker, EW; Henneicke-von Zepelin, HH; Naser-Hijazi, B; Schmeck-Lindenau, HJ; Schnitker, J1
KOSUGE, T1
ROBIN, V1
Adam, BS; Pentz, R; Siegers, CP; Strubelt, O; Tegtmeier, M1
Fujieda, M; Kamataki, T; Kiyotani, K; Peamkrasatam, S; Sriwatanakul, K; Yamazaki, H; Yoovathaworn, K1
BRAMBEL, CE; MacLEAN, AL2
Aun, R; Belczak, SQ; Beserra, J; Campos, W; Nering, G; Sincos, IR1
Basukriadi, A; Wilkins, RM1
Cristina da Costa Araldi, I; Danesi, CC; de Andrade Fortes, T; de Freitas Bauermann, L; de Souza Vencato, M; Dornelles, GL; Emanuelli Mello, CB; Gindri, AL; Machado, AK; Maciel, RM; Melazzo de Andrade, C; Piber de Souza, T; Sorraila de Oliveira, J1

Reviews

1 review(s) available for coumarin and rutin

ArticleYear
Management of venous edema: insights from an international task force.
    Angiology, 2000, Volume: 51, Issue:1

    Topics: Anticoagulants; Bandages; Calcium Dobesilate; Cardiovascular Agents; Chronic Disease; Controlled Clinical Trials as Topic; Coumarins; Diosmin; Edema; Femoral Vein; Hemostatics; Humans; Leg; Placebos; Rutin; Saphenous Vein; Sclerotherapy; Vasodilator Agents; Venous Insufficiency; Venous Thrombosis

2000

Trials

6 trial(s) available for coumarin and rutin

ArticleYear
Treatment of lymphedema by complex physical therapy, with and without oral and topical benzopyrones: what should therapists and patients expect.
    Lymphology, 1996, Volume: 29, Issue:2

    Topics: Administration, Oral; Administration, Topical; Anticoagulants; Arm; Combined Modality Therapy; Coumarins; Humans; Hydroxyethylrutoside; Leg; Lymphedema; Physical Therapy Modalities; Treatment Outcome

1996
[Prospective double-blind study of prophylaxis of radioxerostomia with Coumarin/Troxerutine in patients with head and neck cancer].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1999, Volume: 175, Issue:8

    Topics: Adult; Aged; Coumarins; Double-Blind Method; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Hydroxyethylrutoside; Male; Middle Aged; Mouth Mucosa; Prospective Studies; Radiation Injuries; Radiation-Protective Agents; Radiotherapy; Salivation; Treatment Outcome; Xerostomia

1999
Single copy of variant CYP2A6 alleles does not confer susceptibility to liver dysfunction in patients treated with coumarin.
    International journal of clinical pharmacology and therapeutics, 2003, Volume: 41, Issue:4

    Topics: Adult; Aged; Anticoagulants; Aryl Hydrocarbon Hydroxylases; Chemical and Drug Induced Liver Injury; Coumarins; Cytochrome P-450 CYP2A6; Double-Blind Method; Drug Combinations; Female; Gene Frequency; Genotype; Humans; Hydroxyethylrutoside; Liver Diseases; Liver Function Tests; Male; Middle Aged; Mixed Function Oxygenases; Polymorphism, Genetic; Prospective Studies; Smoking; Venous Insufficiency

2003
Safety aspects of a coumarin-troxerutin combination regarding liver function in a double-blind placebo-controlled study.
    International journal of clinical pharmacology and therapeutics, 2003, Volume: 41, Issue:5

    Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Anticoagulants; Aspartate Aminotransferases; Coumarins; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; gamma-Glutamyltransferase; Humans; Hydroxyethylrutoside; Liver; Male; Middle Aged

2003
In vivo evaluation of coumarin and nicotine as probe drugs to predict the metabolic capacity of CYP2A6 due to genetic polymorphism in Thais.
    Drug metabolism and pharmacokinetics, 2006, Volume: 21, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Anticoagulants; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; Drug Combinations; Female; Gene Frequency; Genotype; Humans; Hydroxyethylrutoside; Male; Middle Aged; Mixed Function Oxygenases; Nicotine; Nicotinic Agonists; Phenotype; Polymethacrylic Acids; Polymorphism, Genetic; Polyvinyls; Thailand; Tobacco Use Cessation Devices; Umbelliferones

2006
Veno-active drugs for chronic venous disease: A randomized, double-blind, placebo-controlled parallel-design trial.
    Phlebology, 2014, Volume: 29, Issue:7

    Topics: Biomechanical Phenomena; Brazil; Cardiovascular Agents; Chronic Disease; Coumarins; Diosmin; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Foot Joints; Hesperidin; Humans; Hydroxyethylrutoside; Male; para-Aminobenzoates; Plethysmography; Quality of Life; Range of Motion, Articular; Recovery of Function; Surveys and Questionnaires; Time Factors; Treatment Outcome; Venous Insufficiency

2014

Other Studies

11 other study(ies) available for coumarin and rutin

ArticleYear
Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay.
    Journal of natural products, 2002, Volume: 65, Issue:11

    Topics: Acrolein; Alkaloids; Animals; Anthraquinones; Aspirin; Biological Assay; Catalysis; Cinnamomum zeylanicum; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Eugenol; Flavonoids; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Kinetics; Lactones; Models, Molecular; Nitrobenzenes; Oleanolic Acid; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Pyrogallol; Steroids; Sulfonamides; Sulfones; Syzygium; Terpenes; Triterpenes; Ursolic Acid

2002
Antidiabetic effect, antioxidant activity, and toxicity of 3',4'-Di-O-acetyl-cis-khellactone in Streptozotocin-induced diabetic rats.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Catalase; Coumarins; Diabetes Mellitus, Experimental; Glutathione; Glutathione Peroxidase; Hypoglycemic Agents; Insulin; Islets of Langerhans; Liver; Mutagenicity Tests; Oxidative Stress; Rats; Salmonella typhimurium; Streptozocin; Superoxide Dismutase

2016
Natural products as inhibitors of Leishmania major dihydroorotate dehydrogenase.
    European journal of medicinal chemistry, 2018, Sep-05, Volume: 157

    Topics: Biological Products; Calorimetry, Differential Scanning; Dihydroorotate Dehydrogenase; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Lactones; Leishmania major; Models, Molecular; Molecular Structure; Oxidoreductases Acting on CH-CH Group Donors; Quantitative Structure-Activity Relationship; Sesquiterpenes

2018
[Microcirculatory consequences of a venous striction in the rat. Effect of a coumarine-rutine association].
    Journal des maladies vasculaires, 1998, Volume: 23, Issue:3

    Topics: Animals; Anticoagulants; Blood Flow Velocity; Constriction, Pathologic; Coumarins; Drug Therapy, Combination; Erythrocytes; Male; Microcirculation; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Rutin

1998
Studies on the identity of bound coumarin in sweet clover.
    Archives of biochemistry and biophysics, 1961, Volume: 95

    Topics: Coumarins; Drug Combinations; Melilotus; Plants, Medicinal; Resins, Plant; Rutin

1961
[Sweet clover disease].
    Revue de pathologie comparee, 1952, Volume: 52, Issue:636

    Topics: Animals; Cattle; Cattle Diseases; Coumarins; Drug Combinations; Medicago; Melilotus; Resins, Plant; Rutin; Trifolium

1952
Troxerutin protects the isolated perfused rat liver from a possible lipid peroxidation by coumarin.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2005, Volume: 12, Issue:1-2

    Topics: Alanine Transaminase; Animals; Anticoagulants; Bile; Chemical and Drug Induced Liver Injury; Coumarins; Glutamate Dehydrogenase; Hydroxyethylrutoside; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Melilotus; Phytotherapy; Plant Extracts; Protective Agents; Rats; Rats, Wistar

2005
Dicumarol and rutin in retinal vascular disorders.
    Transactions of the American Ophthalmological Society, 1946, Volume: 44

    Topics: Cardiovascular System; Coumarins; Dicumarol; Flavones; Retina; Rutin

1946
Dicumarol and rutin in retinal vascular disorders.
    American journal of ophthalmology, 1947, Volume: 30, Issue:9

    Topics: Coumarins; Dicumarol; Disease; Humans; Retina; Retinal Diseases; Rutin

1947
Oviposition deterrent activities of Pachyrhizus erosus seed extract and other natural products on Plutella xylostella (Lepidoptera: Plutellidae).
    Journal of insect science (Online), 2014, Volume: 14

    Topics: Animals; Brassica; Coumarins; Derris; Female; Insect Repellents; Moths; Oviposition; Pachyrhizus; Plant Extracts; Plant Leaves; Rotenone; Rutin

2014
Preclinical safety assessment of the crude extract from Sida rhombifolia L. aerial parts in experimental models of acute and repeated-dose 28 days toxicity in rats.
    Regulatory toxicology and pharmacology : RTP, 2021, Volume: 124

    Topics: Administration, Oral; Animals; Caffeic Acids; Coumarins; Female; Male; Malvaceae; Plant Components, Aerial; Plant Extracts; Rats; Rutin; Toxicity Tests, Acute; Toxicity Tests, Subacute

2021