Compounds > coumarin

coumarin and nadp

coumarin has been researched along with nadp in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's5 (38.46)18.2507
2000's5 (38.46)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lake, BG; Osborne, DJ; Price, RJ; Walters, DG1
Diehl, H; Schröder, U1
Jansson, I; Schenkman, JB; Voznesensky, AI1
Bogan, DP; Deasy, B; O'Kennedy, R; Smyth, MR1
Koenigs, LL; Peter, RM; Rettie, AE; Thompson, SJ; Trager, WF1
Bondoc, FY; Hong, JY; Huang, WQ; Lee, M; Wang, YY; Yang, CS1
Fujita, K; Kamataki, T; Nakayama, K; Nohmi, T; Tsuruma, K; Yamada, M; Yamazaki, Y1
KRATZ, F; STAUDINGER, H1
Fouda, HG; Khojasteh-Bakht, SC; Prakash, C; Rossulek, MI1
Ekman, S; Fransson-Steen, R; Hagbjörk, AL; Löfgren, S; Terelius, Y1
Guengerich, FP; Kim, D; Wu, ZL1
Chuang, MC; Huang, CC; Lin, CH; Lin, P; Lin, PH1
Murphy, SE; Retzlaff, C; von Weymarn, LB1

Other Studies

13 other study(ies) available for coumarin and nadp

ArticleYear
Identification of o-hydroxyphenylacetaldehyde as a major metabolite of coumarin in rat hepatic microsomes.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1992, Volume: 30, Issue:2

    Topics: Acetaldehyde; Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; Coumarins; Male; Mass Spectrometry; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains

1992
Substrate specificity of the carbon monoxide-dependent cytochrome P-450 kinetics.
    Biochimica et biophysica acta, 1987, Jun-17, Volume: 913, Issue:2

    Topics: Animals; Benzoflavones; Carbon Monoxide; Coumarins; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Metyrapone; Microsomes, Liver; NADP; Substrate Specificity; Swine

1987
Influence of ionic strength on the P450 monooxygenase reaction and role of cytochrome b5 in the process.
    Archives of biochemistry and biophysics, 1994, Volume: 314, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzene Derivatives; Benzphetamine; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes b5; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Osmolar Concentration; Oxidoreductases; Rabbits; Steroid Hydroxylases

1994
Interspecies differences in coumarin metabolism in liver microsomes examined by capillary electrophoresis.
    Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:4

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Electrophoresis, Capillary; Humans; Kinetics; Mammals; Microsomes, Liver; Mixed Function Oxygenases; NADP; Species Specificity; Umbelliferones

1996
Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen.
    Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:12

    Topics: Adolescent; Adult; Aryl Hydrocarbon Hydroxylases; Child; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzyme Activation; Female; Humans; Kinetics; Male; Methoxsalen; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; NADP; NADPH-Ferrihemoprotein Reductase; Recombinant Proteins; Spectrophotometry; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Time Factors

1997
Rat olfactory mucosa displays a high activity in metabolizing methyl tert-butyl ether and other gasoline ethers.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1997, Volume: 40, Issue:2

    Topics: Air Pollutants; Animals; Antineoplastic Agents; Biotransformation; Carbon Monoxide; Carcinogens; Chromatography, Gas; Coumarins; Ethyl Ethers; Gasoline; Male; Methyl Ethers; Mice; Microsomes, Liver; NADP; Olfactory Mucosa; Rats; Rats, Sprague-Dawley

1997
Construction of Salmonella typhimurium YG7108 strains, each coexpressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase.
    Environmental and molecular mutagenesis, 2001, Volume: 38, Issue:4

    Topics: Alkylating Agents; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diclofenac; Ethanolamines; Genetic Engineering; Humans; Midazolam; Mixed Function Oxygenases; Mutagenicity Tests; NADP; NADPH-Ferrihemoprotein Reductase; Nitrosamines; Recombinant Proteins; Salmonella typhimurium; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases

2001
[HYDROXYLATION OF COUMARIN WITH RABBIT LIVER MICROSOMES. 1. DIRECT SPECTRAL FLUROMETRIC MEASUREMENT OF ENZYME ACTIVITY].
    Biochemische Zeitschrift, 1964, May-22, Volume: 339

    Topics: Animals; Coumarins; Hydrolases; Hydroxylation; Liver; Metabolism; Microsomes; Microsomes, Liver; NADP; Rabbits; Research; Spectrum Analysis

1964
Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543.
    Xenobiotica; the fate of foreign compounds in biological systems, 2003, Volume: 33, Issue:12

    Topics: Adolescent; Adult; Aged; Chromans; Coumarins; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Ketoconazole; Kinetics; Male; Mephenytoin; Microsomes, Liver; Middle Aged; NADP; Oxidation-Reduction; Quinidine; Receptors, Leukotriene B4; Recombinant Proteins; Sulfaphenazole; Theophylline

2003
Metabolism of human cytochrome P450 marker substrates in mouse: a strain and gender comparison.
    Xenobiotica; the fate of foreign compounds in biological systems, 2004, Volume: 34, Issue:9

    Topics: Amiodarone; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Chlorzoxazone; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme System; Dextromethorphan; Diclofenac; DNA, Complementary; Ethanolamines; Female; Humans; Kinetics; Lauric Acids; Male; Mephenytoin; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitrophenols; Oxidoreductases, N-Demethylating; Oxygen; Paclitaxel; Phenacetin; Rats; Sex Factors; Species Specificity; Substrate Specificity; Testosterone

2004
Analysis of coumarin 7-hydroxylation activity of cytochrome P450 2A6 using random mutagenesis.
    The Journal of biological chemistry, 2005, Dec-02, Volume: 280, Issue:48

    Topics: Amino Acid Sequence; Aryl Hydrocarbon Hydroxylases; Catalysis; Coumarins; Cytochrome P-450 CYP2A6; Gene Library; Humans; Kinetics; Mixed Function Oxygenases; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Mutation; NADP; Oxygen; Protein Binding; Structure-Activity Relationship; Substrate Specificity; Time Factors

2005
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces oxidative stress, DNA strand breaks, and poly(ADP-ribose) polymerase-1 activation in human breast carcinoma cell lines.
    Toxicology letters, 2007, Volume: 172, Issue:3

    Topics: Benzamides; Benzoflavones; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Survival; Coumarins; DNA Breaks; Environmental Pollutants; Estrogen Receptor alpha; Glutathione; Humans; NAD; NADP; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Polychlorinated Dibenzodioxins; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Tamoxifen

2007
CYP2A6- and CYP2A13-catalyzed metabolism of the nicotine Δ5'(1')iminium ion.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 343, Issue:2

    Topics: Aryl Hydrocarbon Hydroxylases; Catalysis; Chromatography, High Pressure Liquid; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; Enzyme Inhibitors; Humans; Kinetics; NADP; Nicotiana; Nicotine; Nicotinic Agonists; Oxidation-Reduction; Tritium

2012