Compounds > coumarin

coumarin and metyrapone

coumarin has been researched along with metyrapone in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Honkakoski, P; Lang, MA; Mäenpää, J; Pelkonen, O; Syngelmä, T1
Diehl, H; Schröder, U1
Burke, MD; Mayer, RT; Rawlins, MD; Rettie, AE; Williams, FM1
Ding, X; Gonzalez, FJ; Liu, C; Zhuo, X1
Brittebo, EB; Carlsson, C; Franzén, A; Hermansson, V; Lang, M1

Other Studies

6 other study(ies) available for coumarin and metyrapone

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparative studies on coumarin and testosterone metabolism in mouse and human livers. Differential inhibitions by the anti-P450Coh antibody and metyrapone.
    Biochemical pharmacology, 1991, Aug-22, Volume: 42, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Humans; Metyrapone; Mice; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Pyrazoles; Steroid Hydroxylases; Testosterone

1991
Substrate specificity of the carbon monoxide-dependent cytochrome P-450 kinetics.
    Biochimica et biophysica acta, 1987, Jun-17, Volume: 913, Issue:2

    Topics: Animals; Benzoflavones; Carbon Monoxide; Coumarins; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Metyrapone; Microsomes, Liver; NADP; Substrate Specificity; Swine

1987
Major differences between lung, skin and liver in the microsomal metabolism of homologous series of resorufin and coumarin ethers.
    Biochemical pharmacology, 1986, Oct-15, Volume: 35, Issue:20

    Topics: Animals; Benzoflavones; Coumarins; Female; Lung; Metyrapone; Mice; Mice, Inbred BALB C; Microsomes; Microsomes, Liver; Oxazines; Skin; Structure-Activity Relationship

1986
Baculovirus-mediated expression and characterization of rat CYP2A3 and human CYP2a6: role in metabolic activation of nasal toxicants.
    Molecular pharmacology, 1996, Volume: 50, Issue:4

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Baculoviridae; Biotransformation; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Complementary; Enzyme Inhibitors; Fomepizole; Hempa; Humans; Immunoblotting; Male; Methoxsalen; Metyrapone; Mixed Function Oxygenases; Nitriles; Nitrophenols; Olfactory Mucosa; Pyrazoles; Rabbits; Rats; Rats, Wistar; Spodoptera; Substrate Specificity; Testosterone

1996
CYP2A5-mediated activation and early ultrastructural changes in the olfactory mucosa: studies on 2,6-dichlorophenyl methylsulfone.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzene Derivatives; Chlorzoxazone; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P450 Family 2; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Female; Injections, Intraperitoneal; Liver; Metyrapone; Mice; Microscopy, Electron, Transmission; Microsomes, Liver; Mixed Function Oxygenases; Nitriles; Olfactory Mucosa; Pyrazoles; Sulfhydryl Compounds; Sulfones

2006