coumarin and methoxsalen

coumarin has been researched along with methoxsalen in 35 studies

Research

Studies (35)

Timeframe	Studies, this research(%)	All Research%
pre-1990	18 (51.43)	18.7374
1990's	3 (8.57)	18.2507
2000's	7 (20.00)	29.6817
2010's	7 (20.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Marumoto, S; Miyazawa, M	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Hirose, S; Naganuma, M; Nakajima, K; Nakayama, Y; Someya, T	1
Juvonen, R; Mäenpää, J; Pelkonen, O; Raunio, H; Rautio, A	1
Ding, X; Gonzalez, FJ; Liu, C; Zhuo, X	1
Koenigs, LL; Peter, RM; Rettie, AE; Thompson, SJ; Trager, WF	1
Hankins, DC; Kharasch, ED; Taraday, JK	1
Juvonen, R; Pelkonen, O; Taavitsainen, P	1
Baudry, J; Berenbaum, MR; Li, W; Pan, L; Schuler, MA	1
DENTON, CR; FITZPATRICK, TB; LERNER, AB	1
SAVITT, LE	1
COUPERUS, M	1
KANOF, NB	1
LERNER, AB	1
CHRISTIANSEN, JV	1
BLICKENSTAFF, DD; FITZPATRICK, TB; HOPKINS, CE; SWIFT, S	1
KELLY, EW; PINKUS, H	1
ABU-SHADY, H; DIGANGI, FE; SOINE, TO	1
CURTIS, AC; HARRELL, ER; SHELDON, SA	1
ELLIOTT, JA	1
SCHUHMACHERS-BRENDLER, R	1
DANIELS, F; FITZPATRICK, TB; HOPKINS, CE	1
BECKER, SW	1
FITZPATRICK, TB; PATHAK, MA	1
DANIELS, F; FITZPATRICK, TB; HOPKINS, CE; PATHAK, MA	1
DE LA CUESTA ALMONACID, L	1
Chen, Z; Lin, L	1
Funae, Y; Imaida, K; Kamataki, T; Masumura, K; Miyazaki, M; Nohmi, T; Saoo, K; Takeuchi, H; Yamazaki, H; Yokohira, M	1
Griffin, KJ; Hsu, MH; Johnson, EF; Stout, CD; Yano, JK	1
Berenbaum, MR; Niu, G; Rupasinghe, SG; Schuler, MA; Wen, Z; Zeng, RS	1
Lapalikar, GV; Oakeshott, JG; Russell, RJ; Scott, C; Taylor, MC; Warden, AC	1
Akimoto, I; Motegi, K; Nishizono, N; Oda, K; Wada, K; Yamaguchi, Y; Yoshimura, T	1
Aillard, P; Banwell, MG; Cervi, A; Chai, CL; Hazeri, N; Petit, L; Willis, AC	1
Baerson, SR; Ren, Y; Su, YJ; Wang, J; Wang, RL; Xia, QQ; Zeng, RS; Zheng, SC	1
Li, Q; Ran, C; Shi, Q; Song, Y; Sun, Z; Wang, H; Wang, R; Xu, C; Zeng, R	1

Trials

1 trial(s) available for coumarin and methoxsalen

Article	Year
Single-dose methoxsalen effects on human cytochrome P-450 2A6 activity. Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:1 Topics: Administration, Oral; Adult; Analysis of Variance; Anticoagulants; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Coumarins; Cross-Over Studies; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Female; Humans; Male; Methoxsalen; Mixed Function Oxygenases; Molecular Probes; Umbelliferones	2000

Article

Year

Single-dose methoxsalen effects on human cytochrome P-450 2A6 activity.

Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:1

Topics: Administration, Oral; Adult; Analysis of Variance; Anticoagulants; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Coumarins; Cross-Over Studies; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Female; Humans; Male; Methoxsalen; Mixed Function Oxygenases; Molecular Probes; Umbelliferones

2000

Other Studies

34 other study(ies) available for coumarin and methoxsalen

Article	Year
Structure-activity relationships for naturally occurring coumarins as β-secretase inhibitor. Bioorganic & medicinal chemistry, 2012, Jan-15, Volume: 20, Issue:2 Topics: 5-Methoxypsoralen; Amyloid Precursor Protein Secretases; Coumarins; Furocoumarins; Kinetics; Methoxsalen; Protease Inhibitors; Structure-Activity Relationship	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A study of the phototoxicity of lemon oil. Archives of dermatological research, 1985, Volume: 278, Issue:1 Topics: 5-Methoxypsoralen; Animals; Citrus; Coumarins; Furocoumarins; Guinea Pigs; Methoxsalen; Oils, Volatile; Photosensitivity Disorders; Pigmentation Disorders; Skin	1985
Metabolic interactions of methoxsalen and coumarin in humans and mice. Biochemical pharmacology, 1994, Oct-07, Volume: 48, Issue:7 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Kinetics; Male; Methoxsalen; Mice; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases	1994
Baculovirus-mediated expression and characterization of rat CYP2A3 and human CYP2a6: role in metabolic activation of nasal toxicants. Molecular pharmacology, 1996, Volume: 50, Issue:4 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Baculoviridae; Biotransformation; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Complementary; Enzyme Inhibitors; Fomepizole; Hempa; Humans; Immunoblotting; Male; Methoxsalen; Metyrapone; Mixed Function Oxygenases; Nitriles; Nitrophenols; Olfactory Mucosa; Pyrazoles; Rabbits; Rats; Rats, Wistar; Spodoptera; Substrate Specificity; Testosterone	1996
Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen. Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:12 Topics: Adolescent; Adult; Aryl Hydrocarbon Hydroxylases; Child; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzyme Activation; Female; Humans; Kinetics; Male; Methoxsalen; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; NADP; NADPH-Ferrihemoprotein Reductase; Recombinant Proteins; Spectrophotometry; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Time Factors	1997
In vitro inhibition of cytochrome P450 enzymes in human liver microsomes by a potent CYP2A6 inhibitor, trans-2-phenylcyclopropylamine (tranylcypromine), and its nonamine analog, cyclopropylbenzene. Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:3 Topics: Aryl Hydrocarbon Hydroxylases; Benzene Derivatives; Binding Sites; Chlorzoxazone; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Inhibitory Concentration 50; Isoenzymes; Kinetics; Methoxsalen; Microsomes, Liver; Mixed Function Oxygenases; Molecular Structure; Monoterpenes; Spectrophotometry; Terpenes; Tranylcypromine	2001
Molecular docking of substrates and inhibitors in the catalytic site of CYP6B1, an insect cytochrome p450 monooxygenase. Protein engineering, 2003, Volume: 16, Issue:8 Topics: 5-Methoxypsoralen; Amino Acid Substitution; Animals; Aryl Hydrocarbon Hydroxylases; Catalytic Domain; Computer Simulation; Coumarins; Furocoumarins; Insect Proteins; Methoxsalen; Models, Molecular; Pilocarpine; Protein Binding; Structural Homology, Protein	2003
Clinical and experimental studies with 8-methoxypsoralen in vitiligo. The Journal of investigative dermatology, 1953, Volume: 20, Issue:4 Topics: Coumarins; Humans; Methoxsalen; Ultraviolet Rays; Ultraviolet Therapy; Vitiligo	1953
Treatment of alopecia areata with ammoidin-ammidin solution; preliminary report. A.M.A. archives of dermatology and syphilology, 1954, Volume: 70, Issue:2 Topics: Alopecia; Alopecia Areata; Coumarins; Humans; Methoxsalen; Pharmaceutical Solutions; Solutions	1954
Ammoidin (xanthotoxin) in the treatment of vitiligo. California medicine, 1954, Volume: 81, Issue:6 Topics: Adult; Ammi; Coumarins; Dermatitis; Female; Furocoumarins; Humans; Methoxsalen; Recurrence; Research Personnel; Ultraviolet Rays; Vitiligo	1954
Melanin formation in vitiliginous skin under the influence of external applications of 8-methoxypsoralen. The Journal of investigative dermatology, 1955, Volume: 24, Issue:1 Topics: Coumarins; Humans; Leadership; Melanins; Methoxsalen; Skin; Ultraviolet Rays; Ultraviolet Therapy; Vitiligo	1955
Potentiation of suntanning through ingestion of 8-methoxypsoralen. The Journal of investigative dermatology, 1955, Volume: 25, Issue:1 Topics: Coumarins; Methoxsalen; Sunbathing; Sunlight	1955
[Meladinine in therapy of vitiligo]. Ugeskrift for laeger, 1955, Jun-09, Volume: 117, Issue:23 Topics: Coumarins; Humans; Methoxsalen; Vitiligo	1955
Augmented pigmentation and other responses of normal human skin to solar radiation following oral adminstration of 8-methoxypsoralen. The Journal of investigative dermatology, 1955, Volume: 25, Issue:3 Topics: Coumarins; Humans; Methoxsalen; Pigmentation; Skin; Sunlight	1955
Local application of 8-methoxypsoralen in vitiligo. The Journal of investigative dermatology, 1955, Volume: 25, Issue:6 Topics: Coumarins; Methoxsalen; Vitiligo	1955
A note on the isolation of bergapten and imperatorin from the fruits of Pastinaca sativa L. Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1956, Volume: 45, Issue:6 Topics: 5-Methoxypsoralen; Coumarins; Fruit; Furocoumarins; Methoxsalen; Pastinaca; Plants	1956
Results in the treatment of vitiligo with 8-methoxypsoralen. A.M.A. archives of dermatology, 1956, Volume: 74, Issue:1 Topics: Coumarins; Humans; Methoxsalen; Vitiligo	1956
The treatment of vitiligo with 8-methoxypsoralen. Southern medical journal, 1956, Volume: 49, Issue:7 Topics: Coumarins; Methoxsalen; Vitiligo	1956
[Corrective dermatology. VI. Treatment of vitiligo with meladinine]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1956, Volume: 7, Issue:11 Topics: Coumarins; Dermatology; Methoxsalen; Vitiligo	1956
Effects of oral methoxsalen (8-methoxypsoralen) on sunburn and suntan; a blind clinical trial. A.M.A. archives of dermatology, 1958, Volume: 77, Issue:5 Topics: Blindness; Coumarins; Humans; Methoxsalen; Sunburn; Suntan; Visually Impaired Persons	1958
Effects of 8-methoxypsoralen and ultraviolet light in human skin. Science (New York, N.Y.), 1958, Apr-18, Volume: 127, Issue:3303 Topics: Coumarins; Humans; Methoxsalen; Skin; Ultraviolet Rays	1958
Historical aspects of methoxsalen and other furocoumarins. The Journal of investigative dermatology, 1959, Volume: 32, Issue:2, Part 2 Topics: Coumarins; Furans; Furocoumarins; Methoxsalen	1959
Ultra-violet carcinogenesis in albino and pigmented mice receiving furocoumarins: psoralen and 8-methoxypsoralen. Nature, 1959, Mar-14, Volume: 183, Issue:4663 Topics: Animals; Carcinogenesis; Coumarins; Ficusin; Furans; Furocoumarins; Methoxsalen; Mice; Neoplasms; Neoplasms, Experimental; Ultraviolet Rays; Viola	1959
[Pelada and ammoidins]. Actas dermo-sifiliograficas, 1954, Volume: 46, Issue:3 Topics: Alopecia; Alopecia Areata; Coumarins; Humans; Methoxsalen	1954
[Study on coumarin compounds from Exocarpium Citri Grandis]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2004, Volume: 27, Issue:8 Topics: 5-Methoxypsoralen; Citrus; Coumarins; Fruit; Furocoumarins; Methoxsalen; Molecular Structure; Plants, Medicinal	2004
Mechanisms of chemopreventive effects of 8-methoxypsoralen against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung adenomas. Carcinogenesis, 2005, Volume: 26, Issue:11 Topics: Adenoma; Animals; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Carcinogens; Chemoprevention; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Escherichia coli Proteins; Female; Humans; Lung Neoplasms; Methoxsalen; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microsomes; Mixed Function Oxygenases; Mutation; Nitrosamines; Pentosyltransferases; Proteins; Salmonella typhimurium; Steroid Hydroxylases	2005
Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen. Nature structural & molecular biology, 2005, Volume: 12, Issue:9 Topics: Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2A6; Humans; Methoxsalen; Microsomes; Mixed Function Oxygenases; Models, Molecular; Protein Structure, Tertiary	2005
Aflatoxin B1 detoxification by CYP321A1 in Helicoverpa zea. Archives of insect biochemistry and physiology, 2008, Volume: 69, Issue:1 Topics: Aflatoxin B1; Aflatoxins; Animals; Binding Sites; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 Enzyme System; Gene Expression; Glutathione; Indoles; Insect Proteins; Kinetics; Larva; Mass Spectrometry; Methoxsalen; Mice; Models, Molecular; Moths; Rats; RNA, Messenger	2008
F420H2-dependent degradation of aflatoxin and other furanocoumarins is widespread throughout the actinomycetales. PloS one, 2012, Volume: 7, Issue:2 Topics: Aflatoxins; Anti-Bacterial Agents; Bacterial Proteins; Coumarins; Flavins; Furocoumarins; Gene Expression Regulation; Hydrolysis; Khellin; Mass Spectrometry; Methoxsalen; Mycobacterium smegmatis; Oxidoreductases; Phylogeny; Species Specificity; Xenobiotics	2012
Synthetic models related to methoxalen and menthofuran-cytochrome P450 (CYP) 2A6 interactions. benzofuran and coumarin derivatives as potent and selective inhibitors of CYP2A6. Chemical & pharmaceutical bulletin, 2013, Volume: 61, Issue:10 Topics: Aryl Hydrocarbon Hydroxylases; Benzofurans; Coumarins; Cytochrome P-450 CYP2A6; Enzyme Inhibitors; Humans; Models, Chemical; Monoterpenes; Protein Binding	2013
Total syntheses of the coumarin-containing natural products pimpinellin and fraxetin using Au(I)-catalyzed intramolecular hydroarylation (IMHA) chemistry. The Journal of organic chemistry, 2013, Oct-04, Volume: 78, Issue:19 Topics: Biological Products; Catalysis; Coumarins; Gold; Hydroxylation; Methoxsalen; Molecular Structure; Organic Chemistry Phenomena	2013
A novel cytochrome P450 CYP6AB14 gene in Spodoptera litura (Lepidoptera: Noctuidae) and its potential role in plant allelochemical detoxification. Journal of insect physiology, 2015, Volume: 75 Topics: Amino Acid Sequence; Animals; Coumarins; Cytochrome P-450 Enzyme System; Digestive System; Enzyme Induction; Flavones; Insect Proteins; Larva; Methoxsalen; Molecular Sequence Data; Pheromones; RNA Interference; RNA, Double-Stranded; Spodoptera	2015
Identification of a cytochrome P450 CYP6AB60 gene associated with tolerance to multi-plant allelochemicals from a polyphagous caterpillar tobacco cutworm (Spodoptera litura). Pesticide biochemistry and physiology, 2019, Volume: 154 Topics: Animals; Coumarins; Cytochrome P450 Family 6; Drug Tolerance; Gene Expression Regulation, Enzymologic; Insect Proteins; Larva; Methoxsalen; Pheromones; RNA Interference; Spodoptera; Tomatine	2019