coumarin and methotrexate

coumarin has been researched along with methotrexate in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (22.22)	18.2507
2000's	3 (33.33)	29.6817
2010's	4 (44.44)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Jolivette, LJ; Ward, KW	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Xu, Z; Zhang, L	1
Petrylak, D; Yagoda, A	1
Fahrig, R; Steinkamp-Zucht, A	1

Reviews

2 review(s) available for coumarin and methotrexate

Article	Year
Coumarin-containing hybrids and their anticancer activities. European journal of medicinal chemistry, 2019, Nov-01, Volume: 181 Topics: Animals; Antineoplastic Agents; Coumarins; Drug Design; Drug Discovery; Humans; Neoplasms; Structure-Activity Relationship	2019
Cytotoxic chemotherapy for advanced hormone-resistant prostate cancer. Cancer, 1993, Feb-01, Volume: 71, Issue:3 Suppl Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bone Neoplasms; Cisplatin; Clinical Trials as Topic; Coumarins; Doxorubicin; Drug Administration Schedule; Drug Resistance; Fluorouracil; Humans; Intercalating Agents; Male; Methotrexate; Neoplasm Staging; Polyamines; Prostate-Specific Antigen; Prostatic Neoplasms; Remission Induction; Somatostatin	1993

Article

Year

Coumarin-containing hybrids and their anticancer activities.

European journal of medicinal chemistry, 2019, Nov-01, Volume: 181

Topics: Animals; Antineoplastic Agents; Coumarins; Drug Design; Drug Discovery; Humans; Neoplasms; Structure-Activity Relationship

2019

Cytotoxic chemotherapy for advanced hormone-resistant prostate cancer.

Cancer, 1993, Feb-01, Volume: 71, Issue:3 Suppl

Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bone Neoplasms; Cisplatin; Clinical Trials as Topic; Coumarins; Doxorubicin; Drug Administration Schedule; Drug Resistance; Fluorouracil; Humans; Intercalating Agents; Male; Methotrexate; Neoplasm Staging; Polyamines; Prostate-Specific Antigen; Prostatic Neoplasms; Remission Induction; Somatostatin

1993

Other Studies

7 other study(ies) available for coumarin and methotrexate

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Induction or suppression of SV40 amplification by genotoxic carcinogens, non-genotoxic carcinogens or tumor promoters. Mutation research, 1996, Sep-23, Volume: 356, Issue:2 Topics: Acetamides; Acetone; Anthracenes; Carcinogens; Cell Line, Transformed; Coumarins; Deoxyuridine; Dimethylformamide; Diterpenes; DNA, Viral; Mercaptopurine; Methotrexate; Mutagens; Nitroquinolines; Nucleic Acid Hybridization; Simian virus 40; Terpenes; Testosterone; Tetradecanoylphorbol Acetate; Thioacetamide; Virus Replication	1996