coumarin has been researched along with esculetin in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 11 (68.75) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Davio, C; de Celis, ER; Facorro, G; Gomez, N; Moglioni, A; Piehl, L; Riveiro, ME; Shayo, C; Vazquez, R | 1 |
| Adachi, I; Hirono, S; Kato, A; Kobayashi, K; Minoshima, Y; Narukawa, K; Nash, RJ | 1 |
| Marumoto, S; Miyazawa, M | 1 |
| Battastini, AM; Bernardi, A; Eifler-Lima, VL; Figueiró, F; Hamerski, L; Pinto, AC; Pires, EN; Salbego, CG; Teixeira, HF; Vianna, DR; Visentin, LC; von Poser, GL | 1 |
| Barbosa-Filho, JM; de Aquino, TM; de Araújo, RS; de Moura, RO; de O Lima, E; de Simone, CA; Guerra, FQ; Mendonça, FJ; Scotti, L; Scotti, MT; Tavares, JF | 1 |
| Ge, GB; Gonzalez, FJ; Li, SY; Liu, Y; Wang, JJ; Wang, P; Xia, YL | 1 |
| BRAYMER, HD; PETRAKIS, PL; SHETLAR, MR; WENDER, SH; YANG, CH | 1 |
| NICHELE, G; PIANTONI, D | 1 |
| Atmaca, M; Deniz Obay, B; Ketani, A; Murat Bilgin, H; Ozekinci, S; Taşdemir, E | 1 |
| Mercer, DK; Miller, L; O Neil, DA; Robertson, J; Smith, S; Stewart, CS; Wright, K | 1 |
| Barbosa-Filho, JM; de Araujo Leite, JC; de Castro, TM; de Siqueira-Junior, JP; Marques-Santos, LF | 1 |
| Cheng, AX; Gao, S; Lou, HX; Xu, RX; Zhao, Y | 1 |
| Hagiwara, S; Itagaki, H; Miyazaki, H; Shinoda, S; Takahashi, H; Yamashita, K | 1 |
| Huang, C; Kong, L; Sui, Z; Wang, N; Zeng, Z; Zhao, Y | 1 |
| Xu, Y; Zhang, G; Zhou, HF | 1 |
| Hong, K; Jeong, SK; Lee, BZ; Lee, IS; Lee, S; Pham, CH; Yoo, HM | 1 |
16 other study(ies) available for coumarin and esculetin
| Article | Year |
|---|---|
Structural insights into hydroxycoumarin-induced apoptosis in U-937 cells.
Topics: Apoptosis; Biological Products; Coumarins; Electron Spin Resonance Spectroscopy; Humans; Hydroxylation; Kinetics; Molecular Structure; Structure-Activity Relationship; U937 Cells | 2008 |
6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2.
Topics: Aldehyde Reductase; Animals; Binding Sites; Computer Simulation; Coumarins; Galactitol; L-Iditol 2-Dehydrogenase; Lens, Crystalline; Protein Structure, Tertiary; Rats; Rhodanine; Structure-Activity Relationship; Thiazolidines | 2010 |
Structure-activity relationships for naturally occurring coumarins as β-secretase inhibitor.
Topics: 5-Methoxypsoralen; Amyloid Precursor Protein Secretases; Coumarins; Furocoumarins; Kinetics; Methoxsalen; Protease Inhibitors; Structure-Activity Relationship | 2012 |
Selective cytotoxicity and apoptosis induction in glioma cell lines by 5-oxygenated-6,7-methylenedioxycoumarins from Pterocaulon species.
Topics: Animals; Antineoplastic Agents; Apoptosis; Asteraceae; Benzodioxoles; Cell Line, Tumor; Cell Survival; Central Nervous System Neoplasms; Coumarins; Cytotoxins; Glioma; Hippocampus; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Male; Organ Specificity; Rats; Rats, Wistar; Structure-Activity Relationship; Tissue Culture Techniques | 2012 |
Synthesis, structure-activity relationships (SAR) and in silico studies of coumarin derivatives with antifungal activity.
Topics: Acetylation; Alkylation; Antifungal Agents; Aspergillus; Computer Simulation; Coumarins; Least-Squares Analysis; Microbial Sensitivity Tests; Models, Chemical; Models, Molecular; Molecular Structure; Nitrates; Principal Component Analysis; Structure-Activity Relationship | 2013 |
Synthesis and structure-activity relationship of coumarins as potent Mcl-1 inhibitors for cancer treatment.
Topics: A549 Cells; Antineoplastic Agents; Cell Proliferation; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Myeloid Cell Leukemia Sequence 1 Protein; Structure-Activity Relationship; Tumor Cells, Cultured | 2021 |
Formation of scopoletin from esculin and esculetin in the rat.
Topics: Animals; Coumarins; Esculin; Flavonoids; Rats; Scopoletin; Umbelliferones; Vitamins | 1958 |
[Diseases of children with increased capillary fragility treated with a disulfuric ester of 4-methyl-esculetin].
Topics: Capillary Fragility; Coumarins; Esters; Humans; Umbelliferones | 1951 |
Protective effects of coumarin and coumarin derivatives against carbon tetrachloride-induced acute hepatotoxicity in rats.
Topics: Animals; Antioxidants; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Coumarins; Hymecromone; Male; Rats; Rats, Sprague-Dawley; Umbelliferones | 2011 |
A prodrug approach to the use of coumarins as potential therapeutics for superficial mycoses.
Topics: Antifungal Agents; Arthrodermataceae; Bacteria; beta-Glucosidase; Coumarins; Dermatomycoses; Drosophila Proteins; Esculin; Humans; Hydrolysis; Microbial Sensitivity Tests; Microbiota; Prodrugs; Skin; Umbelliferones | 2013 |
Photoprotective effect of coumarin and 3-hydroxycoumarin in sea urchin gametes and embryonic cells.
Topics: Animals; Coumarins; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Female; Male; Ovum; Protective Agents; Radiation-Protective Agents; Sea Urchins; Spermatozoa; Ultraviolet Rays; Umbelliferones; Zygote | 2015 |
Functional characterization of a Mg(2+)-dependent O-methyltransferase with coumarin as preferred substrate from the liverwort Plagiochasma appendiculatum.
Topics: Amino Acid Sequence; Biosynthetic Pathways; Cloning, Molecular; Coumarins; Electrophoresis, Polyacrylamide Gel; Hepatophyta; Kinetics; Magnesium; Methyltransferases; Phylogeny; Recombinant Proteins; Scopoletin; Sequence Alignment; Subcellular Fractions; Substrate Specificity; Umbelliferones | 2016 |
Assessment of the skin sensitizing potential of chemicals, contained in foods and/or cosmetic ingredients, using a modified local lymph node assay with an elicitation phase (LLNA:DAE) method.
Topics: Animals; Carmine; Cosmetics; Coumarins; Curcumin; Dose-Response Relationship, Drug; Female; Food Analysis; Local Lymph Node Assay; Mice, Inbred CBA; Naphthoquinones; Quercetin; Skin; Skin Irritancy Tests; Umbelliferones | 2018 |
The Molecular and Structural Basis of
Topics: Amino Acid Sequence; Apiaceae; Biosynthetic Pathways; Coumarins; Data Mining; Evolution, Molecular; Furocoumarins; Gene Duplication; Heterozygote; Methylation; Methyltransferases; Molecular Docking Simulation; Phytochemicals; S-Adenosylhomocysteine; Sequence Analysis, RNA; Substrate Specificity; Transcriptome; Umbelliferones | 2019 |
Esculetin Inhibits Proliferation, Invasion, and Migration of Laryngeal Cancer In Vitro and In Vivo by Inhibiting Janus Kinas (JAK)-Signal Transducer and Activator of Transcription-3 (STAT3) Activation.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Coumarins; Gene Expression Regulation, Neoplastic; Humans; Janus Kinases; Laryngeal Neoplasms; Mice; Mice, Nude; Neoplasm Invasiveness; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; Umbelliferones; Xenograft Model Antitumor Assays | 2019 |
Apoptosis in Leukemic Cells Induced by Anti-proliferative Coumarin Isolated from the Stem Bark of
Topics: Apoptosis; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coumarins; Fraxinus; Humans; Jurkat Cells; Membrane Potential, Mitochondrial; Mitochondria; Plant Bark; Plant Extracts; Reactive Oxygen Species; Signal Transduction; Umbelliferones | 2020 |