coumarin and chalcone

coumarin has been researched along with chalcone in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's0 (0.00)29.6817
2010's7 (53.85)24.3611
2020's5 (38.46)2.80

Authors

AuthorsStudies
Abeygunawardana, C; Dinkova-Kostova, AT; Talalay, P1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Bhatia, G; Khanna, AK; Kumar, M; Modukuri, RK; Rai, S; Sashidhara, KV; Shukla, R; Sonkar, R1
Borges, F; Kachler, S; Klotz, KN; Matos, MJ; Santana, L; Uriarte, E; Vazquez-Rodriguez, S1
Mandi, P; Nantasenamat, C; Pingaew, R; Prachayasittikul, S; Prachayasittikul, V; Ruchirawat, S; Saekee, A1
Alvarez-Idaboy, JR; Galano, A; Mazzone, G; Russo, N1
Abou-Zied, OK; Ghasemi, A; Karimi-Jafari, MH; Khammari, A; Khoobi, M; Saboury, AA; Yousefinejad, S1
Chang, KH; Chen, CM; Chiu, YJ; Huang, CC; Lee, SY; Lee-Chen, GJ; Lin, W; Yang, SM1
Dong, J; Gao, J; Wang, Y; Zhang, W1
Danduga, RCSR; Kola, PK; Konidala, SK; Kotra, V1
Alanazi, MM; Amran, SI; Biswas, S; Chander, S; Das, B; Hadda, TB; Hasan, AH; Jamalis, J; Murugesan, S; Pratama, MRF; Shakya, S1
Kumar, A; Kumar, S1
Çelik Onar, H; Ece, A; Erçağ, E; Gülçin, İ; Özden, EM; Taslak, HD1

Other Studies

13 other study(ies) available for coumarin and chalcone

ArticleYear
Chemoprotective properties of phenylpropenoids, bis(benzylidene)cycloalkanones, and related Michael reaction acceptors: correlation of potencies as phase 2 enzyme inducers and radical scavengers.
    Journal of medicinal chemistry, 1998, Dec-17, Volume: 41, Issue:26

    Topics: Animals; Anticarcinogenic Agents; Chalcone; Cinnamates; Coumarins; Enzyme Induction; Free Radical Scavengers; Liver Neoplasms, Experimental; Luminescent Measurements; Magnetic Resonance Spectroscopy; Mice; Molecular Conformation; NAD(P)H Dehydrogenase (Quinone); Structure-Activity Relationship; Superoxides; Tumor Cells, Cultured

1998
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Synthesis and anti-inflammatory activity of novel biscoumarin-chalcone hybrids.
    Bioorganic & medicinal chemistry letters, 2011, Aug-01, Volume: 21, Issue:15

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chalcone; Coumarins; Edema; Microsomes; Rats

2011
Chalcone-based derivatives as new scaffolds for hA3 adenosine receptor antagonists.
    The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:5

    Topics: Animals; Binding, Competitive; Chalcone; CHO Cells; Coumarins; Cricetinae; Cricetulus; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptor, Adenosine A3; Structure-Activity Relationship; Thiophenes

2013
Synthesis, biological evaluation and molecular docking of novel chalcone-coumarin hybrids as anticancer and antimalarial agents.
    European journal of medicinal chemistry, 2014, Oct-06, Volume: 85

    Topics: Antimalarials; Antineoplastic Agents; Cell Line, Tumor; Chalcone; Chemistry Techniques, Synthetic; Coumarins; Cysteine Endopeptidases; Humans; Molecular Docking Simulation; Plasmodium falciparum; Protein Conformation; Triazoles; Tubulin

2014
Coumarin-Chalcone Hybrids as Peroxyl Radical Scavengers: Kinetics and Mechanisms.
    Journal of chemical information and modeling, 2016, 04-25, Volume: 56, Issue:4

    Topics: Chalcone; Coumarins; Free Radical Scavengers; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Conformation; Peroxides; Solvents; Water

2016
Insights into the molecular interaction between two polyoxygenated cinnamoylcoumarin derivatives and human serum albumin.
    Physical chemistry chemical physics : PCCP, 2017, Apr-12, Volume: 19, Issue:15

    Topics: Binding Sites; Calorimetry; Chalcone; Circular Dichroism; Coumarins; Fluorescence Resonance Energy Transfer; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Serum Albumin, Human; Spectrometry, Fluorescence; Static Electricity; Thermodynamics

2017
Novel synthetic chalcone-coumarin hybrid for Aβ aggregation reduction, antioxidation, and neuroprotection.
    CNS neuroscience & therapeutics, 2018, Volume: 24, Issue:12

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Antioxidants; Cell Line, Tumor; Chalcone; Coumarins; Dose-Response Relationship, Drug; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Inhibitory Concentration 50; Neuroblastoma; Neuronal Outgrowth; Protein Aggregates; Reactive Oxygen Species; RNA Interference; RNA, Messenger; Transfection

2018
Design, synthesis and bioactivity evaluation of coumarin-chalcone hybrids as potential anticancer agents.
    Bioorganic chemistry, 2020, Volume: 95

    Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Chalcone; Coumarins; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Fluorescent Dyes; HCT116 Cells; Humans; Inhibitory Concentration 50; Precision Medicine; Reactive Oxygen Species; Structure-Activity Relationship; Thioredoxin-Disulfide Reductase

2020
Coumarin-chalcone hybrids targeting insulin receptor: Design, synthesis, anti-diabetic activity, and molecular docking.
    Bioorganic chemistry, 2020, Volume: 104

    Topics: Administration, Oral; Animals; Antigens, CD; Chalcone; Coumarins; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Design; Female; Humans; Hypoglycemic Agents; Injections, Intraperitoneal; Male; Molecular Docking Simulation; Molecular Structure; Rats; Rats, Wistar; Receptor, Insulin; Streptozocin; Structure-Activity Relationship

2020
Novel thiophene Chalcones-Coumarin as acetylcholinesterase inhibitors: Design, synthesis, biological evaluation, molecular docking, ADMET prediction and molecular dynamics simulation.
    Bioorganic chemistry, 2022, Volume: 119

    Topics: Acetylcholinesterase; Alzheimer Disease; Cells, Cultured; Chalcone; Cholinesterase Inhibitors; Coumarins; Dose-Response Relationship, Drug; Drug Design; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Thiophenes

2022
Synthesis, Computational and Pharmacological Evaluation of 7-(2-(2- (3- (Substituted Phenyl) Acryloyl) Phenoxy) Ethoxy)-4-Methyl-2H-Chromen- 2-Ones as CNS Agents.
    Central nervous system agents in medicinal chemistry, 2023, Volume: 23, Issue:1

    Topics: Animals; Central Nervous System Agents; Chalcone; Coumarins; Diazepam; Mice; Prospective Studies; Structure-Activity Relationship

2023
Novel coumarin-chalcone derivatives: Synthesis, characterization, antioxidant, cyclic voltammetry, molecular modelling and biological evaluation studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors.
    Chemico-biological interactions, 2023, Sep-25, Volume: 383

    Topics: Acetylcholinesterase; Antioxidants; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Chalcone; Cholinesterase Inhibitors; Coumarins; Glycoside Hydrolases; Humans; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship

2023