coumarin and aspirin

coumarin has been researched along with aspirin in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's13 (35.14)18.2507
2000's18 (48.65)29.6817
2010's4 (10.81)24.3611
2020's2 (5.41)2.80

Authors

AuthorsStudies
Gubernator, K; Kansy, M; Senner, F1
Topliss, JG; Yoshida, F1
Bohlin, L; Huss, U; Perera, P; Ringbom, T; Vasänge, M1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Balliano, TL; Barbosa, G; Carvalho, VF; da Silva, BA; de Souza, ET; Lima, LM; Martins, IRR; Martins, MA; Medeiros, MM; Moraes Junior, MO; Nunes, IKDC; Silva, PMR; Silva, SWD1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Bär, FW; de Swart, JB; van der Veen, FH; van Ommen, V; van Oppen, J; Wellens, HJ1
Kessler, CM1
Beer, JH; Rihs, F; Sturzenegger, M1
Debruyne, FM; Doesburg, W; vd Meijden, AP; Witjes, JA1
Dick, B; Jacobi, FK1
Fondevila, CG; Frontroth, J; Lazzari, MA; Meschengieser, SS; Santarelli, MT1
Boda, Z; Bódi, A; Csapó, K; Hegedús, I; Medgyesi, F; Pfliegler, G; Voith, L1
Anderson, LM; Jones, AB; Liao, AM; Liu, Y; Smith, TJ; Yang, CS1
Schipper, JP1
Ghali, JK1
Grobbee, DE; Kardinaal, AF; Kruijssen, DA; Princen, HM; van de Vijver, LP; van Duyvenvoorde, W; van Poppel, G1
Hellemons, BS; Knottnerus, JA; Langenberg, M; Lemmens, T; Lodder, J; Schouten, HJ; van Ree, JW; Vermeer, F1
Franke, A1
Bailey, SR; Baim, DS; Cleman, MW; Deutsch, E; Diver, DJ; Fitzgerald, PJ; Hayase, M; Kuntz, RE; Leon, MB; Metz, JA; Moses, JW; Oesterle, SN; Oshima, A; Overlie, PA; Pepine, CJ; Safian, RD; Shani, J; Simonton, CA; Smalling, RW; Teirstein, PS; Yeung, AC; Yock, PG; Zidar, JP1
Buurma, H; Egberts, AC; Leufkens, HG; Rahimtoola, H; Tijssen, CC1
Graatsma, HH; Stricker, BH; Visser, LE1
Altorjay, I; Palatka, K; Tornai, I; Udvardy, M1
Aengevaeren, WR; Brouwer, MA; Hertzberger, DP; Luijten, HE; Uijen, GJ; van Boven, AJ; van den Bergh, PJ; Veen, G; Verheugt, FW; Vromans, RP1
Hak, E; Hoes, AW; Rutten, FH; Stalman, WA; Verheij, TJ1
Baumgartner, RW; Gandjour, J; Georgiadis, D; Zeindler, J1
Cieślik, T; Cieślik-Bielewska, A; Pelc, R1
Lengyel, M1
Belvís, R; Bravo, Y; Castellanos, M; Cocho, D; Egido, J; Geffner, D; Gich, I; Gil-Núñez, A; Marta, J; Martí-Fàbregas, J; Martí-Vilalta, JL; Millán, M; Navarro, R; Obach, V; Palomeras, E; Rodríguez-Campello, A1
Rath, W; Richter, ON1
Aengevaeren, WR; Brouwer, MA; Kievit, PC; van den Bergh, PJ; Veen, G; Verheugt, FW1
Grzywna, E; Krupa, M; Moskała, M; Składzień, T1
Erastov, AA; Kostanyan, AE; Shishilov, ON1
Erastov, AA; Kostanyan, AE1

Reviews

6 review(s) available for coumarin and aspirin

ArticleYear
The pharmacology of aspirin, heparin, coumarin, and thrombolytic agents. Implications for therapeutic use in cardiopulmonary disease.
    Chest, 1991, Volume: 99, Issue:4 Suppl

    Topics: Aspirin; Coumarins; Fibrinolytic Agents; Heparin; Humans; Thromboembolism; Thrombolytic Therapy; Thrombosis

1991
Contemporary issues in heart failure.
    American heart journal, 1999, Volume: 138, Issue:1 Pt 1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Anticoagulants; Aspirin; Community Health Services; Coumarins; Heart Failure; Humans; Hypertension; Myocardial Ischemia; Stroke Volume; United States; Ventricular Dysfunction, Left

1999
[Acute gastrointestinal bleeding in patients with antithrombotic therapy].
    Orvosi hetilap, 2002, Jan-27, Volume: 143, Issue:4

    Topics: Acute Disease; Anticoagulants; Aspirin; Coumarins; Deamino Arginine Vasopressin; Gastrointestinal Hemorrhage; Heart Valve Prosthesis; Hemostatics; Heparin; Humans; Thrombolytic Therapy; Ticlopidine

2002
[Antithrombotic therapy in patients with first-ever stroke and known non-rheumatic atrial fibrillation].
    Praxis, 2005, Jan-26, Volume: 94, Issue:4

    Topics: Administration, Oral; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Coumarins; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Primary Prevention; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Assessment; Risk Factors; Stroke

2005
[Triplex antithrombotic therapy after coronary-stent implantation (that is absent from recommendation)].
    Orvosi hetilap, 2005, Sep-11, Volume: 146, Issue:37

    Topics: Aspirin; Clopidogrel; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Coumarins; Drug Therapy, Combination; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; Secondary Prevention; Stents; Ticlopidine

2005
[Thromboembolic diseases in pregnancy].
    Zeitschrift fur Geburtshilfe und Neonatologie, 2007, Volume: 211, Issue:1

    Topics: Algorithms; Anticoagulants; Aspirin; Contraindications; Coumarins; Female; Heparin; Heparin, Low-Molecular-Weight; Humans; Pregnancy; Pregnancy Complications; Pulmonary Embolism; Risk Factors; Venous Thrombosis

2007

Trials

7 trial(s) available for coumarin and aspirin

ArticleYear
Low-intensity oral anticoagulation plus low-dose aspirin versus high-intensity oral anticoagulation alone: a randomized trial in patients with mechanical prosthetic heart valves.
    The Journal of thoracic and cardiovascular surgery, 1997, Volume: 113, Issue:5

    Topics: Anticoagulants; Aspirin; Coumarins; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Heart Valve Prosthesis; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Thromboembolism; Time Factors

1997
[Coumarin combined with low-dose acetylsalicylic acid in the prevention of thromboembolic complications in patients with mitral and aortic valve prostheses].
    Orvosi hetilap, 1997, Apr-13, Volume: 138, Issue:15

    Topics: Adolescent; Adult; Aged; Anticoagulants; Aortic Valve; Aspirin; Coumarins; Female; Heart Valve Prosthesis; Humans; Male; Middle Aged; Mitral Valve; Thromboembolism

1997
Primary prevention of arterial thromboembolism in non-rheumatic atrial fibrillation in primary care: randomised controlled trial comparing two intensities of coumarin with aspirin.
    BMJ (Clinical research ed.), 1999, Oct-09, Volume: 319, Issue:7215

    Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Coumarins; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Survival Analysis; Thromboembolism; Treatment Outcome

1999
Final results of the Can Routine Ultrasound Influence Stent Expansion (CRUISE) study.
    Circulation, 2000, Aug-01, Volume: 102, Issue:5

    Topics: Aspirin; Coronary Angiography; Coronary Disease; Coronary Vessels; Coumarins; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Stents; Ticlopidine; Treatment Outcome; Ultrasonography, Interventional

2000
Aspirin plus coumarin versus aspirin alone in the prevention of reocclusion after fibrinolysis for acute myocardial infarction: results of the Antithrombotics in the Prevention of Reocclusion In Coronary Thrombolysis (APRICOT)-2 Trial.
    Circulation, 2002, Aug-06, Volume: 106, Issue:6

    Topics: Anticoagulants; Aspirin; Coronary Angiography; Coronary Disease; Coumarins; Disease-Free Survival; Drug Therapy, Combination; Female; Fibrinolytic Agents; Follow-Up Studies; Hemorrhage; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Thrombolytic Therapy; Treatment Outcome

2002
Aspirin or anticoagulants in stenosis of the middle cerebral artery: A randomized trial.
    Cerebrovascular diseases (Basel, Switzerland), 2006, Volume: 22, Issue:2-3

    Topics: Aged; Anticoagulants; Aspirin; Cerebral Arterial Diseases; Cerebrovascular Disorders; Constriction, Pathologic; Coumarins; Female; Humans; Male; Middle Cerebral Artery; Platelet Aggregation Inhibitors; Treatment Outcome

2006
Prolonged anticoagulation therapy adjunctive to aspirin after successful fibrinolysis: from early reduction in reocclusion to improved long-term clinical outcome.
    American heart journal, 2009, Volume: 157, Issue:3

    Topics: Aged; Anticoagulants; Aspirin; Coronary Occlusion; Coumarins; Hemorrhage; Humans; International Normalized Ratio; Myocardial Infarction; Recurrence; Thrombolytic Therapy; Treatment Outcome

2009

Other Studies

24 other study(ies) available for coumarin and aspirin

ArticleYear
Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes.
    Journal of medicinal chemistry, 1998, Mar-26, Volume: 41, Issue:7

    Topics: Absorption; Adsorption; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Permeability; Pharmacokinetics; Spectrophotometry, Ultraviolet

1998
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay.
    Journal of natural products, 2002, Volume: 65, Issue:11

    Topics: Acrolein; Alkaloids; Animals; Anthraquinones; Aspirin; Biological Assay; Catalysis; Cinnamomum zeylanicum; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Eugenol; Flavonoids; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Kinetics; Lactones; Models, Molecular; Nitrobenzenes; Oleanolic Acid; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Pyrogallol; Steroids; Sulfonamides; Sulfones; Syzygium; Terpenes; Triterpenes; Ursolic Acid

2002
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies.
    European journal of medicinal chemistry, 2020, Oct-15, Volume: 204

    Topics: Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Design; Enzyme Inhibitors; Humans; Hydrazones; Hypersensitivity; Lung; Male; Mice

2020
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Complications after intracoronary stent implantation: three cases.
    Cardiology, 1992, Volume: 80, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Coronary Angiography; Coronary Disease; Coumarins; Dipyridamole; Drug Administration Schedule; Electrocardiography; Exercise Test; Follow-Up Studies; Heparin; Humans; Male; Middle Aged; Premedication; Recurrence; Stents

1992
Monitoring combined antithrombotic treatments in patients with prosthetic heart valves using transcranial Doppler and coagulation markers.
    Stroke, 1995, Volume: 26, Issue:1

    Topics: Administration, Oral; Adult; Antithrombin III; Aspirin; beta-Thromboglobulin; Biomarkers; Coumarins; Drug Therapy, Combination; Female; Fibrin Fibrinogen Degradation Products; Fibrinolytic Agents; Fibrinopeptide A; Heart Valve Prosthesis; Heparin; Humans; Injections, Intravenous; Male; Middle Aged; Peptide Hydrolases; Postoperative Complications; Thromboembolism; Ultrasonography, Doppler, Transcranial

1995
Influence of fibrin clot inhibitors on the efficacy of intravesical Bacillus Calmette-Guérin in the treatment of superficial bladder cancer. The Dutch Southeast Cooperative Urological Group.
    European urology, 1993, Volume: 23, Issue:3

    Topics: Administration, Intravesical; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; BCG Vaccine; Carcinoma in Situ; Carcinoma, Transitional Cell; Coumarins; Dipyridamole; Fibrin; Humans; Male; Random Allocation; Urinary Bladder Neoplasms; Warfarin

1993
[Cataract surgery and anticoagulation--current status].
    Klinische Monatsblatter fur Augenheilkunde, 1996, Volume: 209, Issue:6

    Topics: Anticoagulants; Aspirin; Blood Loss, Surgical; Cataract Extraction; Coumarins; Heparin; Humans; Patient Care Team; Prothrombin Time; Risk Factors; Thromboembolism

1996
Enzymes involved in the bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in patas monkey lung and liver microsomes.
    Carcinogenesis, 1997, Volume: 18, Issue:8

    Topics: Animals; Aspirin; Biotransformation; Carbon Monoxide; Coumarins; Cytochrome P-450 Enzyme System; Erythrocebus patas; Female; Isothiocyanates; Lipoxygenase; Lung; Masoprocol; Microsomes; Microsomes, Liver; Nitrosamines; Oxygenases; Prostaglandin-Endoperoxide Synthases

1997
[Consensus on antithrombotic prophylaxis of vascular events in patients with manifested atherosclerotic vascular disease].
    Nederlands tijdschrift voor geneeskunde, 1998, Mar-28, Volume: 142, Issue:13

    Topics: Aged; Anticoagulants; Arteriosclerosis; Aspirin; Atrial Fibrillation; Cerebrovascular Disorders; Coumarins; Humans; Ischemic Attack, Transient

1998
Oxidation of LDL and extent of peripheral atherosclerosis.
    Free radical research, 1999, Volume: 31, Issue:2

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antihypertensive Agents; Arteriosclerosis; Aspirin; Cholesterol, Dietary; Coumarins; Diet, Fat-Restricted; Humans; Lipid Peroxidation; Lipoproteins, LDL; Male; Middle Aged; Odds Ratio; Risk Factors

1999
[Prevention of embolism in atrial septal defects?].
    Deutsche medizinische Wochenschrift (1946), 2000, Apr-20, Volume: 125 Suppl 1

    Topics: Adult; Age Factors; Anticoagulants; Aspirin; Coumarins; Embolism; Female; Fibrinolytic Agents; Heart Septal Defects, Atrial; Humans; Platelet Aggregation Inhibitors; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Time Factors; Venous Thrombosis

2000
Reduction in the intensity of abortive migraine drug use during coumarin therapy.
    Headache, 2001, Volume: 41, Issue:8

    Topics: Anticoagulants; Aspirin; Coumarins; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ergotamine; Female; Follow-Up Studies; Humans; Male; Middle Aged; Migraine Disorders; Retrospective Studies; Severity of Illness Index; Sumatriptan; Vasoconstrictor Agents

2001
Contraindicated NSAIDs are frequently prescribed to elderly patients with peptic ulcer disease.
    British journal of clinical pharmacology, 2002, Volume: 53, Issue:2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Aspirin; Cohort Studies; Contraindications; Coumarins; Drug Interactions; Drug Prescriptions; Female; Glucocorticoids; Humans; Male; Osteoarthritis; Peptic Ulcer Hemorrhage; Retrospective Studies

2002
Is treatment of atrial fibrillation in primary care based on thromboembolic risk assessment?
    Family practice, 2003, Volume: 20, Issue:1

    Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Coumarins; Cross-Sectional Studies; Evidence-Based Medicine; Female; Humans; Logistic Models; Male; Middle Aged; Practice Patterns, Physicians'; Primary Health Care; Risk Assessment; Thromboembolism

2003
Oral surgery procedures in patients on anticoagulants. Preliminary report.
    Kardiologia polska, 2005, Volume: 63, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Cardiovascular Diseases; Coumarins; Female; Humans; International Normalized Ratio; Male; Middle Aged; Oral Surgical Procedures; Partial Thromboplastin Time; Platelet Aggregation Inhibitors; Treatment Outcome

2005
[Influence of anticoagulants on the appearance of chronic subdural hematoma].
    Przeglad lekarski, 2009, Volume: 66, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Cardiovascular Diseases; Chronic Disease; Coumarins; Female; Hematoma, Subdural; Heparin, Low-Molecular-Weight; Humans; Incidence; Male; Middle Aged; Poland; Surveys and Questionnaires

2009
Multiple dual mode counter-current chromatography with variable duration of alternating phase elution steps.
    Journal of chromatography. A, 2014, Jun-20, Volume: 1347

    Topics: Aspirin; Caffeine; Coumarins; Countercurrent Distribution; Models, Theoretical; Salicylic Acid

2014
Theoretical study of closed-loop recycling liquid-liquid chromatography and experimental verification of the theory.
    Journal of chromatography. A, 2016, Sep-02, Volume: 1462

    Topics: Acetates; Aspirin; Caffeine; Coumarins; Countercurrent Distribution; Ethanol; Hexanes; Models, Theoretical; Recycling; Reproducibility of Results; Solutions; Solvents; Water

2016