coumarin 3,4-epoxide has been researched along with acetaldehyde in 3 studies
*Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis. [MeSH]
*Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis. [MeSH]
| Studies (coumarin 3,4-epoxide) | Trials (coumarin 3,4-epoxide) | Recent Studies (post-2010) (coumarin 3,4-epoxide) | Studies (acetaldehyde) | Trials (acetaldehyde) | Recent Studies (post-2010) (acetaldehyde) |
|---|---|---|---|---|---|
| 7 | 0 | 0 | 6,226 | 77 | 1,268 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Born, SL; Hu, JK; Lehman-McKeeman, LD | 1 |
| Born, SL; Caudill, D; Lehman-McKeeman, LD; Smith, BJ | 1 |
| Daston, GP; Hicks, SM; Lehman-McKeeman, LD; Vassallo, JD | 1 |
3 other study(ies) available for coumarin 3,4-epoxide and acetaldehyde
| Article | Year |
|---|---|
o-hydroxyphenylacetaldehyde is a hepatotoxic metabolite of coumarin.
Topics: Acetaldehyde; Animals; Anticoagulants; Cell Survival; Cells, Cultured; CHO Cells; Coumarins; Cricetinae; Gas Chromatography-Mass Spectrometry; Liver; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley | 2000 |
In vitro kinetics of coumarin 3,4-epoxidation: application to species differences in toxicity and carcinogenicity.
Topics: Acetaldehyde; Adult; Animals; Anticoagulants; Antineoplastic Agents; Child, Preschool; Chromatography, Gas; Coumarins; Female; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Middle Aged; Rats; Rats, Inbred F344; Species Specificity | 2000 |
Metabolic detoxification determines species differences in coumarin-induced hepatotoxicity.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Oxidase; Animals; Anticoagulants; Chemical and Drug Induced Liver Injury; Coumarins; Cytosol; Female; Glutathione; Humans; Inactivation, Metabolic; Indicators and Reagents; Male; Mice; Microsomes, Liver; Oxidation-Reduction; Phenylacetates; Rats; Rats, Inbred F344; Species Specificity | 2004 |