Page last updated: 2024-09-02

cotinine-n-oxide and nicotine

cotinine-n-oxide has been researched along with nicotine in 11 studies

Compound Research Comparison

Studies
(cotinine-n-oxide)
Trials
(cotinine-n-oxide)
Recent Studies (post-2010)
(cotinine-n-oxide)
Studies
(nicotine)
Trials
(nicotine)
Recent Studies (post-2010) (nicotine)
140428,5192,2809,302

Protein Interaction Comparison

ProteinTaxonomycotinine-n-oxide (IC50)nicotine (IC50)
Neuronal acetylcholine receptor subunit alpha-4Mus musculus (house mouse)0.0055
Acetylcholine receptor subunit alphaTetronarce californica (Pacific electric ray)0.0025
Acetylcholine receptor subunit betaTetronarce californica (Pacific electric ray)0.0025
Acetylcholine receptor subunit gammaTetronarce californica (Pacific electric ray)0.0025
Acetylcholine receptor subunit deltaTetronarce californica (Pacific electric ray)0.0025
Neuronal acetylcholine receptor subunit alpha-3Rattus norvegicus (Norway rat)0.005
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.0046
Neuronal acetylcholine receptor subunit alpha-2Rattus norvegicus (Norway rat)0.005
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.0046
Neuronal acetylcholine receptor subunit beta-3Rattus norvegicus (Norway rat)0.005
Neuronal acetylcholine receptor subunit beta-4Rattus norvegicus (Norway rat)0.005
Neuronal acetylcholine receptor subunit beta-2Homo sapiens (human)0.3256
Neuronal acetylcholine receptor subunit alpha-5Rattus norvegicus (Norway rat)0.005
Acetylcholine receptor subunit beta-like 2Drosophila melanogaster (fruit fly)4
Neuronal acetylcholine receptor subunit beta-4Homo sapiens (human)0.43
Neuronal acetylcholine receptor subunit alpha-3Homo sapiens (human)0.1866
Neuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)7.6
Neuronal acetylcholine receptor subunit alpha-6Rattus norvegicus (Norway rat)0.005
Neuronal acetylcholine receptor subunit alpha-9Rattus norvegicus (Norway rat)0.0041
Neuronal acetylcholine receptor subunit alpha-4Homo sapiens (human)0.3456
Neuronal acetylcholine receptor subunit alpha-7Mus musculus (house mouse)0.004
Neuronal acetylcholine receptor subunit beta-3Homo sapiens (human)0.0848
Neuronal acetylcholine receptor subunit alpha-7Rattus norvegicus (Norway rat)0.0087
Neuronal acetylcholine receptor subunit alpha-6Homo sapiens (human)0.0848
Neuronal acetylcholine receptor subunit alpha-5Mus musculus (house mouse)0.004
Liver carboxylesterase B-1Rattus norvegicus (Norway rat)0.045
Neuronal acetylcholine receptor subunit beta-3Mus musculus (house mouse)0.004
Neuronal acetylcholine receptor subunit beta-4Mus musculus (house mouse)0.004
Neuronal acetylcholine receptor subunit alpha-3Mus musculus (house mouse)0.004
Neuronal acetylcholine receptor subunit alpha-2Mus musculus (house mouse)0.004
Neuronal acetylcholine receptor subunit beta-2Mus musculus (house mouse)0.004
Neuronal acetylcholine receptor subunit alpha-10Rattus norvegicus (Norway rat)0.005
Neuronal acetylcholine receptor subunit alpha-6Mus musculus (house mouse)0.004

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's5 (45.45)18.2507
2000's2 (18.18)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kainzbauer, J; Richter, O; Stehlik, G; Tausch, H1
Caldwell, WS; de Bethizy, JD; Doolittle, DJ; Hayes, AW; Lee, CK; Winegar, R1
Andersson, G; Axéll, T; Curvall, M1
Andersson, G; Björnberg, G; Curvall, M1
Altieri, I; Pacifici, R; Passa, AR; Pichini, S; Ricciarello, G; Rosa, M; Zuccaro, P1
Andersson, G; Curvall, M; Vala, EK1
Hee, SS; Yim, SH1
Benowitz, NL; Dempsey, DA; Jacob, P; Kroetz, DL; Tutka, P1
Grata, E; Marclay, F; Perrenoud, L; Saugy, M1
Andrenyak, DM; Fleckenstein, AE; Nielsen, SM; Vieira-Brock, PL; Wilkins, DG1
Bernert, JT; Blount, BC; McGuffey, JE; Morrow, JC; Wang, L; Wei, B; Xia, B1

Other Studies

11 other study(ies) available for cotinine-n-oxide and nicotine

ArticleYear
Improved method for routine determination of nicotine and its main metabolites in biological fluids.
    Journal of chromatography, 1982, Nov-12, Volume: 232, Issue:2

    Topics: Chromatography, Gas; Cotinine; Cyclic N-Oxides; Humans; Nicotine

1982
The genotoxic potential of nicotine and its major metabolites.
    Mutation research, 1995, Volume: 344, Issue:3-4

    Topics: Animals; CHO Cells; Cotinine; Cricetinae; Cyclic N-Oxides; Fluorenes; Mutagenicity Tests; Mutagens; Mutation; Nicotine; Salmonella typhimurium; Sister Chromatid Exchange

1995
Reduction in nicotine intake and oral mucosal changes among users of Swedish oral moist snuff after switching to a low-nicotine product.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1995, Volume: 24, Issue:6

    Topics: Adult; Cotinine; Cyclic N-Oxides; Glucuronates; Humans; Mouth Diseases; Mouth Mucosa; Nicotine; Plants, Toxic; Saliva; Sweden; Time Factors; Tobacco, Smokeless

1995
Oral mucosal changes and nicotine disposition in users of Swedish smokeless tobacco products: a comparative study.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1994, Volume: 23, Issue:4

    Topics: Adult; Cotinine; Glucuronates; Glucuronic Acid; Humans; Leukoedema, Oral; Male; Middle Aged; Mouth Diseases; Mouth Mucosa; Nicotine; Nitrosamines; Plants, Toxic; Saliva; Sweden; Tobacco, Smokeless

1994
Determination of nicotine and four metabolites in the serum of smokers by high-performance liquid chromatography with ultraviolet detection.
    Journal of chromatography, 1993, Nov-24, Volume: 621, Issue:2

    Topics: Chromatography, High Pressure Liquid; Cotinine; Humans; Nicotine; Smoking

1993
The influence of cigarette consumption and smoking machine yields of tar and nicotine on the nicotine uptake and oral mucosal lesions in smokers.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1997, Volume: 26, Issue:3

    Topics: Adult; Cotinine; Cyclic N-Oxides; Environmental Exposure; Glucuronates; Humans; Leukoedema, Oral; Leukoplakia, Oral; Male; Middle Aged; Mouth Diseases; Mouth Mucosa; Nicotiana; Nicotine; Plants, Toxic; Prevalence; Smoking; Tars; Time Factors; Tongue, Hairy

1997
Bacterial mutagenicity of some tobacco aromatic nitrogen bases and their mixtures.
    Mutation research, 2001, May-31, Volume: 492, Issue:1-2

    Topics: Animals; Carcinogens; Cotinine; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Microsomes, Liver; Mutagenicity Tests; Mutagens; Nicotiana; Nicotine; Nitrosamines; Plants, Toxic; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Vibrio

2001
Nicotine metabolism in pregnant and nonpregnant rabbits.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2008, Volume: 10, Issue:8

    Topics: Animals; Blotting, Western; Cotinine; Cytochrome P-450 CYP2D6; Female; Microsomes, Liver; Nicotine; Pregnancy; Pregnancy, Animal; Rabbits

2008
A one-year monitoring of nicotine use in sport: frontier between potential performance enhancement and addiction issues.
    Forensic science international, 2011, Dec-10, Volume: 213, Issue:1-3

    Topics: Alkaloids; Anabasine; Athletes; Chromatography, Liquid; Cotinine; Doping in Sports; Humans; Mass Spectrometry; Nicotine; Performance-Enhancing Substances; Pyridines; Smoking; Spectrometry, Mass, Electrospray Ionization; Tobacco, Smokeless

2011
Age-related differences in the disposition of nicotine and metabolites in rat brain and plasma.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2013, Volume: 15, Issue:11

    Topics: Administration, Cutaneous; Adolescent; Adult; Aging; Animals; Brain; Cotinine; Cyclic N-Oxides; Humans; Male; Nicotine; Rats; Rats, Sprague-Dawley

2013
Validation of a LC-MS/MS method for quantifying urinary nicotine, six nicotine metabolites and the minor tobacco alkaloids--anatabine and anabasine--in smokers' urine.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Alkaloids; Anabasine; Chromatography, Liquid; Cotinine; Humans; Nicotine; Pyridines; Smoking; Tandem Mass Spectrometry

2014