cotinine and coumarin

cotinine has been researched along with coumarin in 7 studies

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (57.14)	29.6817
2010's	3 (42.86)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Juvonen, RO; Poso, A; Rahnasto, M; Raunio, H; Wittekindt, C	1
Aygün Kocabaş, N; Cholerton, S; Cok, I; Karakaya, AE; Sardaş, S	1
Cashman, JR; Fandrick, K; MacDougall, JM; Serafin, SV; Zhang, X	1
Fujieda, M; Kamataki, T; Kiyotani, K; Peamkrasatam, S; Sriwatanakul, K; Yamazaki, H; Yoovathaworn, K	1
Murphy, SE; Retzlaff, C; von Weymarn, LB	1
Capelo, JL; Cavaleiro, JA; Faustino, MA; Lodeiro, C; Menezes, JC; Neves, Mda G; Oliveira, E; Santos, CI; Santos, HM	1
Hirasawa, N; Hiratsuka, M; Hosono, H; Kumondai, M; Maekawa, M; Mano, N; Oda, A; Yamaguchi, H	1

Trials

1 trial(s) available for cotinine and coumarin

Article	Year
In vivo evaluation of coumarin and nicotine as probe drugs to predict the metabolic capacity of CYP2A6 due to genetic polymorphism in Thais. Drug metabolism and pharmacokinetics, 2006, Volume: 21, Issue:6 Topics: Administration, Oral; Adolescent; Adult; Anticoagulants; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; Drug Combinations; Female; Gene Frequency; Genotype; Humans; Hydroxyethylrutoside; Male; Middle Aged; Mixed Function Oxygenases; Nicotine; Nicotinic Agonists; Phenotype; Polymethacrylic Acids; Polymorphism, Genetic; Polyvinyls; Thailand; Tobacco Use Cessation Devices; Umbelliferones	2006

Article

Year

In vivo evaluation of coumarin and nicotine as probe drugs to predict the metabolic capacity of CYP2A6 due to genetic polymorphism in Thais.

Drug metabolism and pharmacokinetics, 2006, Volume: 21, Issue:6

Topics: Administration, Oral; Adolescent; Adult; Anticoagulants; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; Drug Combinations; Female; Gene Frequency; Genotype; Humans; Hydroxyethylrutoside; Male; Middle Aged; Mixed Function Oxygenases; Nicotine; Nicotinic Agonists; Phenotype; Polymethacrylic Acids; Polymorphism, Genetic; Polyvinyls; Thailand; Tobacco Use Cessation Devices; Umbelliferones

2006

Other Studies

6 other study(ies) available for cotinine and coumarin

Article	Year
Quantitative structure-activity relationship analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme. Journal of medicinal chemistry, 2005, Jan-27, Volume: 48, Issue:2 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Cytochrome P450 Family 2; Enzyme Inhibitors; Female; Humans; Male; Mice; Mixed Function Oxygenases; Nicotine; Quantitative Structure-Activity Relationship	2005
Determination of coumarin metabolism in Turkish population. Human & experimental toxicology, 2001, Volume: 20, Issue:4 Topics: Adult; Aged; Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Female; Gene Frequency; Genotype; Humans; Isoenzymes; Male; Middle Aged; Mixed Function Oxygenases; Nicotine; Phenotype; Point Mutation; Polymorphism, Genetic; Smoking; Turkey; Umbelliferones	2001
Inhibition of human liver microsomal (S)-nicotine oxidation by (-)-menthol and analogues. Chemical research in toxicology, 2003, Volume: 16, Issue:8 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Haplorhini; Humans; In Vitro Techniques; Menthol; Microsomes, Liver; Mixed Function Oxygenases; Nicotine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Smoking; Stereoisomerism; Steroid Hydroxylases	2003
CYP2A6- and CYP2A13-catalyzed metabolism of the nicotine Δ5'(1')iminium ion. The Journal of pharmacology and experimental therapeutics, 2012, Volume: 343, Issue:2 Topics: Aryl Hydrocarbon Hydroxylases; Catalysis; Chromatography, High Pressure Liquid; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; Enzyme Inhibitors; Humans; Kinetics; NADP; Nicotiana; Nicotine; Nicotinic Agonists; Oxidation-Reduction; Tritium	2012
Untangling interactions of a zinc(II) complex containing a coumarin-porphyrin unit with alkaloids in water solutions: a photophysical study. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2015, Volume: 14, Issue:4 Topics: Caffeine; Cotinine; Coumarins; Ethanol; Fresh Water; Molecular Structure; Nicotine; Photochemical Processes; Porphyrins; Portugal; Solutions; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrum Analysis; Ultraviolet Rays; Zinc	2015
Functional Characterization of 34 CYP2A6 Allelic Variants by Assessment of Nicotine C-Oxidation and Coumarin 7-Hydroxylation Activities. Drug metabolism and disposition: the biological fate of chemicals, 2017, Volume: 45, Issue:3 Topics: Alleles; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; HEK293 Cells; Humans; Hydroxylation; Kinetics; Microsomes; Models, Molecular; Nicotine; Oxidation-Reduction; Polymorphism, Genetic; Substrate Specificity; Transfection; Umbelliferones	2017