Page last updated: 2024-09-04

cositecan and topotecan

cositecan has been researched along with topotecan in 2 studies

Compound Research Comparison

Studies (cositecan)	Trials (cositecan)	Recent Studies (post-2010) (cositecan)	Studies (topotecan)	Trials (topotecan)	Recent Studies (post-2010) (topotecan)
20	5	2	2,392	626	792

Protein Interaction Comparison

Protein	Taxonomy	topotecan (IC50)
Cytochrome P450 3A4	Homo sapiens (human)	1.5211
DNA topoisomerase 1	Homo sapiens (human)	0.8525
DNA topoisomerase 2-alpha	Homo sapiens (human)	0.605
DNA topoisomerase 2-beta	Homo sapiens (human)	0.605
Hypoxia-inducible factor 1-alpha	Homo sapiens (human)	0.06
Multidrug and toxin extrusion protein 2	Homo sapiens (human)	8.6
Multidrug and toxin extrusion protein 1	Homo sapiens (human)	1.3
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	0.17

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Boven, E; Hausheer, FH; Pinedo, HM; Schlüper, HM; Van Hattum, AH	1
Bailly, C; Lansiaux, A	1

Other Studies

2 other study(ies) available for cositecan and topotecan

Article	Year
Novel camptothecin derivative BNP1350 in experimental human ovarian cancer: determination of efficacy and possible mechanisms of resistance. International journal of cancer, 2002, Jul-01, Volume: 100, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Camptothecin; Cell Division; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Irinotecan; Mice; Mice, Nude; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neoplasm Transplantation; Ovarian Neoplasms; Topoisomerase I Inhibitors; Topotecan; Transplantation, Heterologous; Tumor Cells, Cultured	2002
[A symphony for the camptothecins]. Bulletin du cancer, 2003, Volume: 90, Issue:3 Topics: Antineoplastic Agents; Camptothecin; Enzyme Inhibitors; Irinotecan; Music; Neoplasms; Organosilicon Compounds; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topotecan	2003

Article

Year

Novel camptothecin derivative BNP1350 in experimental human ovarian cancer: determination of efficacy and possible mechanisms of resistance.

International journal of cancer, 2002, Jul-01, Volume: 100, Issue:1

Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Camptothecin; Cell Division; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Irinotecan; Mice; Mice, Nude; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neoplasm Transplantation; Ovarian Neoplasms; Topoisomerase I Inhibitors; Topotecan; Transplantation, Heterologous; Tumor Cells, Cultured

2002

[A symphony for the camptothecins].

Bulletin du cancer, 2003, Volume: 90, Issue:3

Topics: Antineoplastic Agents; Camptothecin; Enzyme Inhibitors; Irinotecan; Music; Neoplasms; Organosilicon Compounds; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topotecan

2003