Page last updated: 2024-09-04

cositecan and irinotecan

cositecan has been researched along with irinotecan in 5 studies

Compound Research Comparison

Studies
(cositecan)
Trials
(cositecan)
Recent Studies (post-2010)
(cositecan)
Studies
(irinotecan)
Trials
(irinotecan)
Recent Studies (post-2010) (irinotecan)
20528,0021,8853,752

Protein Interaction Comparison

ProteinTaxonomycositecan (IC50)irinotecan (IC50)
Solute carrier family 22 member 2Homo sapiens (human)2.7
Interstitial collagenaseHomo sapiens (human)6.06
Muscarinic acetylcholine receptor M4Homo sapiens (human)1.556
Alpha-2C adrenergic receptorHomo sapiens (human)3.171
AcetylcholinesteraseHomo sapiens (human)1.827
Multidrug and toxin extrusion protein 2Homo sapiens (human)7.9
Multidrug and toxin extrusion protein 1Homo sapiens (human)4.7667

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boven, E; Hausheer, FH; Pinedo, HM; Schlüper, HM; Van Hattum, AH2
Bigner, DD; Friedman, HS; Hausheer, F; Keir, ST; Lawless, AA1
Bailly, C; Lansiaux, A1
Pappo, A; Paulino, AC1

Other Studies

5 other study(ies) available for cositecan and irinotecan

ArticleYear
New highly lipophilic camptothecin BNP1350 is an effective drug in experimental human cancer.
    International journal of cancer, 2000, Oct-15, Volume: 88, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Colonic Neoplasms; Doxorubicin; Drug Resistance, Multiple; Enzyme Inhibitors; Female; Humans; Irinotecan; Lung Neoplasms; Melanoma; Mice; Mice, Nude; Neoplasms; Ovarian Neoplasms; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2000
Therapeutic activity of 7-[(2-trimethylsilyl)ethyl)]-20 (S)-camptothecin against central nervous system tumor-derived xenografts in athymic mice.
    Cancer chemotherapy and pharmacology, 2001, Volume: 48, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Female; Humans; Irinotecan; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous

2001
Novel camptothecin derivative BNP1350 in experimental human ovarian cancer: determination of efficacy and possible mechanisms of resistance.
    International journal of cancer, 2002, Jul-01, Volume: 100, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Camptothecin; Cell Division; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Irinotecan; Mice; Mice, Nude; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neoplasm Transplantation; Ovarian Neoplasms; Topoisomerase I Inhibitors; Topotecan; Transplantation, Heterologous; Tumor Cells, Cultured

2002
[A symphony for the camptothecins].
    Bulletin du cancer, 2003, Volume: 90, Issue:3

    Topics: Antineoplastic Agents; Camptothecin; Enzyme Inhibitors; Irinotecan; Music; Neoplasms; Organosilicon Compounds; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topotecan

2003
Alveolar rhabdomyosarcoma of the extremity and nodal metastasis: Is the in-transit lymphatic system at risk?
    Pediatric blood & cancer, 2009, Dec-15, Volume: 53, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Camptothecin; Child; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Dactinomycin; Etoposide; Fatal Outcome; Female; Foot; Groin; Humans; Ifosfamide; Irinotecan; Lymph Node Excision; Lymphatic Metastasis; Lymphatic System; Male; Niacinamide; Phenylurea Compounds; Pyridines; Radiotherapy, Adjuvant; Radiotherapy, High-Energy; Rhabdomyosarcoma, Alveolar; Salvage Therapy; Soft Tissue Neoplasms; Sorafenib; Temozolomide; Thigh; Vincristine

2009