Page last updated: 2024-09-04

corydalmine and berberine

corydalmine has been researched along with berberine in 12 studies

Compound Research Comparison

Studies
(corydalmine)
Trials
(corydalmine)
Recent Studies (post-2010)
(corydalmine)
Studies
(berberine)
Trials
(berberine)
Recent Studies (post-2010) (berberine)
170134,1061022,791

Protein Interaction Comparison

ProteinTaxonomycorydalmine (IC50)berberine (IC50)
AcetylcholinesteraseElectrophorus electricus (electric eel)0.7827
Lysine-specific histone demethylase 1AHomo sapiens (human)6.97
CholinesteraseHomo sapiens (human)1.09
AcetylcholinesteraseHomo sapiens (human)0.4
Aldo-keto reductase family 1 member C3Homo sapiens (human)4.99
Aldo-keto reductase family 1 member C2 Homo sapiens (human)6.71
CholinesteraseEquus caballus (horse)9.4
Cytochrome P450 1B1Homo sapiens (human)0.9747

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (58.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Chen, Y; Jin, GZ; Lin, GD; Xuan, JC1
IMASEKI, I; TAGUCHI, H1
BRADSHER, CK; TELANG, SA1
Dai, HF; Guo, ZK; Liu, SB; Mei, WL; Wang, QH; Wei, DJ; Yang, DL; Zeng, YB1
Chen, Y; Di, X; Ling, Z; Liu, L; Liu, X; Tang, X; Wang, F; Wang, Z; Xie, Q; Xu, P; Zhao, K; Zhong, Z1
Abdallah, IA; Hassan, HE; Huang, P; Lee, DY; Liu, J; Liu-Chen, LY1
Dai, WL; Jiang, N; Liu, JH; Liu, XF; Wu, JJ; Yan, B; Yu, BY1
Gao, L; Liu, J; Shu, M; Yu, B; Zhang, H1
Ao, L; Fang, W; Hu, Y; Li, C; Li, Y; Liu, J; Yan, Y; Yu, B; Zhou, L1
Bao, YN; Dai, WL; Jiang, N; Liu, JH; Liu, XT; Yan, B; Yu, BY1
Ao, L; Fang, W; Hu, Y; Li, C; Li, W; Li, Y; Liu, J; Yan, Y; Ye, A; Zhou, L1
Bao, YN; Dai, WL; Fan, JF; Li, SS; Liu, JH; Yu, BY; Zhao, WL1

Other Studies

12 other study(ies) available for corydalmine and berberine

ArticleYear
[Relevance of stereo and quantum chemistry of four tetrahydroprotoberberines to their effects on dopamine receptors].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:3

    Topics: Alkaloids; Animals; Berberine; Berberine Alkaloids; Cattle; Molecular Conformation; Quantum Theory; Rats; Receptors, Dopamine; Stereoisomerism; Structure-Activity Relationship

1988
[Studies on the components of Corydalis spp. I. Alkaloids of the Chinese Corydalis. On the new bases corydalmine and dehydrocorydalmine].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1962, Volume: 82

    Topics: Alkaloids; Berberine; Corydalis; Humans

1962
THE SYNTHESIS OF 10-HYDROXY-2,3,9-TRIMETHOXYDIBENZO(A,G)QUINOLIZIDINE. A CONTRIBUTION TO THE STRUCTURE OF THE CORYDALMINE ALKALOIDS.
    The Journal of organic chemistry, 1965, Volume: 30

    Topics: Alkaloids; Berberine; Chemical Phenomena; Chemistry; Heterocyclic Compounds; Quinolizidines; Research

1965
A new antibacterial denitroaristolochic acid from the tubers of Stephania succifera.
    Journal of Asian natural products research, 2013, Volume: 15, Issue:3

    Topics: Alkaloids; Anti-Bacterial Agents; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenanthrenes; Plant Tubers; Staphylococcus aureus; Stephania

2013
In vitro metabolism of l-corydalmine, a potent analgesic drug, in human, cynomolgus monkey, beagle dog, rat and mouse liver microsomes.
    Journal of pharmaceutical and biomedical analysis, 2016, Sep-05, Volume: 128

    Topics: Analgesics; Animals; Berberine; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Dogs; Humans; Hydroxylation; Kinetics; Macaca fascicularis; Mice; Microsomes, Liver; Rats; Tandem Mass Spectrometry

2016
Development and validation of a high performance liquid chromatography quantification method of levo-tetrahydropalmatine and its metabolites in plasma and brain tissues: application to a pharmacokinetic study.
    Biomedical chromatography : BMC, 2017, Volume: 31, Issue:4

    Topics: Animals; Berberine; Berberine Alkaloids; Brain; Calibration; Chromatography, High Pressure Liquid; Drug Stability; Heterocyclic Compounds, 4 or More Rings; Liquid-Liquid Extraction; Male; Rats, Sprague-Dawley; Sensitivity and Specificity

2017
Simultaneous inhibition of NMDA and mGlu1/5 receptors by levo-corydalmine in rat spinal cord attenuates bone cancer pain.
    International journal of cancer, 2017, 08-15, Volume: 141, Issue:4

    Topics: Animals; Berberine; Bone Neoplasms; Calcium; Cancer Pain; Gene Expression Regulation, Neoplastic; Injections, Spinal; Male; Neoplasm Transplantation; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spinal Cord; Treatment Outcome

2017
Development of a highly sensitive and specific ELISA method for the determination of l-corydalmine in SD rats with monoclonal antibody.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018, Jan-15, Volume: 1073

    Topics: Animals; Antibodies, Monoclonal; Berberine; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Limit of Detection; Linear Models; Liver; Myocardium; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2018
Levo-corydalmine alleviates vincristine-induced neuropathic pain in mice by inhibiting an NF-kappa B-dependent CXCL1/CXCR2 signaling pathway.
    Neuropharmacology, 2018, Volume: 135

    Topics: Animals; Astrocytes; Berberine; Cells, Cultured; Chemokine CXCL1; Dose-Response Relationship, Drug; Male; Mice; Neuralgia; Neurons; NF-kappa B; Oxycodone; Phosphorylation; Receptors, Interleukin-8B; RNA, Small Interfering; Signal Transduction; Transcription Factor RelA; Vincristine

2018
Selective blockade of spinal D2DR by levo-corydalmine attenuates morphine tolerance via suppressing PI3K/Akt-MAPK signaling in a MOR-dependent manner.
    Experimental & molecular medicine, 2018, 11-14, Volume: 50, Issue:11

    Topics: Analgesics, Opioid; Animals; Berberine; Cell Line, Tumor; CHO Cells; Chronic Pain; Cricetinae; Cricetulus; Dopamine Antagonists; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Male; MAP Kinase Signaling System; Mice; Morphine; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Opioid, mu

2018
Levo-corydalmine Attenuates Vincristine-Induced Neuropathic Pain in Mice by Upregulating the Nrf2/HO-1/CO Pathway to Inhibit Connexin 43 Expression.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2020, Volume: 17, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Astrocytes; Berberine; Connexin 43; Encephalitis; Heme Oxygenase-1; Male; Membrane Proteins; Mice, Inbred ICR; Neuralgia; NF-E2-Related Factor 2; Sciatic Nerve; Signal Transduction; Spinal Cord; Up-Regulation; Vincristine

2020
Levo
    Regional anesthesia and pain medicine, 2020, Volume: 45, Issue:3

    Topics: Animals; Berberine; Interleukin-1beta; Male; MAP Kinase Kinase Kinase 5; Microglia; Neuralgia; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Signal Transduction; Spinal Cord; Tumor Necrosis Factor-alpha

2020