cortodoxone and 3-4-5-3--4--5--hexachlorobiphenyl

cortodoxone has been researched along with 3-4-5-3--4--5--hexachlorobiphenyl* in 1 studies

Other Studies

1 other study(ies) available for cortodoxone and 3-4-5-3--4--5--hexachlorobiphenyl

Article	Year
Differential effects of 3,4,5,3',4',5'-hexachlorobiphenyl (HCB) on interrenal steroidogenesis in male and female rainbow trout Oncorhynchus mykiss. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1992, Volume: 103, Issue:1 1. The conversion of progesterone to 17 alpha-hydroxyprogesterone (17 alpha-OHP), 11-deoxycortisol (11-DOCR) and deoxycorticosterone (DOC) was significantly higher in female rainbow trout than in male trout; in contrast, the interrenal production of cortisol (CR) plus cortisone (CN) was higher in males than in females. 2. Following treatment with 1 mg/kg of HCB, the interrenal conversion of progesterone to 17 alpha-OHP and 11-DOCR was significantly increased in male and female trout but at 20 mg/kg of HCB, the production of these metabolites was increased in males and decreased in females; CR+CN production was unchanged after HCB treatment in both sexes. Topics: 17-alpha-Hydroxyprogesterone; Animals; Autoradiography; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cortisone; Cortodoxone; Desoxycorticosterone; Female; Hydrocortisone; Hydroxyprogesterones; Interrenal Gland; Male; Polychlorinated Biphenyls; Progesterone; Sex Characteristics; Steroids; Trout	1992

Article

Year

Differential effects of 3,4,5,3',4',5'-hexachlorobiphenyl (HCB) on interrenal steroidogenesis in male and female rainbow trout Oncorhynchus mykiss.

Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1992, Volume: 103, Issue:1

1. The conversion of progesterone to 17 alpha-hydroxyprogesterone (17 alpha-OHP), 11-deoxycortisol (11-DOCR) and deoxycorticosterone (DOC) was significantly higher in female rainbow trout than in male trout; in contrast, the interrenal production of cortisol (CR) plus cortisone (CN) was higher in males than in females. 2. Following treatment with 1 mg/kg of HCB, the interrenal conversion of progesterone to 17 alpha-OHP and 11-DOCR was significantly increased in male and female trout but at 20 mg/kg of HCB, the production of these metabolites was increased in males and decreased in females; CR+CN production was unchanged after HCB treatment in both sexes.

Topics: 17-alpha-Hydroxyprogesterone; Animals; Autoradiography; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cortisone; Cortodoxone; Desoxycorticosterone; Female; Hydrocortisone; Hydroxyprogesterones; Interrenal Gland; Male; Polychlorinated Biphenyls; Progesterone; Sex Characteristics; Steroids; Trout

1992