cortistatin-14 and isoquinoline

cortistatin-14 has been researched along with isoquinoline* in 1 studies

Other Studies

1 other study(ies) available for cortistatin-14 and isoquinoline

Article	Year
Total synthesis of cortistatins A and J. The Journal of organic chemistry, 2011, Apr-15, Volume: 76, Issue:8 This paper describes the details of our synthetic studies on the marine steroidal alkaloids cortistatins A and J. The key features of our strategy include (i) an efficient Knoevenagel/electrocyclic strategy to couple the diketone and the CD-ring fragment, (ii) a chemoselective radical cyclization to construct the oxabicyclo[3.2.1]octene B-ring system, (iii) a highly stereocontrolled installation of the isoquinoline unit, and (iv) a late-stage functionalization of the A-ring. Topics: Alkaloids; Angiogenesis Inhibitors; Animals; Aquatic Organisms; Cyclization; Heterocyclic Compounds, 4 or More Rings; Isoquinolines; Ketones; Neovascularization, Pathologic; Neovascularization, Physiologic; Neuropeptides; Polycyclic Compounds; Porifera; Stereoisomerism; Steroids	2011

Article

Year

Total synthesis of cortistatins A and J.

The Journal of organic chemistry, 2011, Apr-15, Volume: 76, Issue:8

This paper describes the details of our synthetic studies on the marine steroidal alkaloids cortistatins A and J. The key features of our strategy include (i) an efficient Knoevenagel/electrocyclic strategy to couple the diketone and the CD-ring fragment, (ii) a chemoselective radical cyclization to construct the oxabicyclo[3.2.1]octene B-ring system, (iii) a highly stereocontrolled installation of the isoquinoline unit, and (iv) a late-stage functionalization of the A-ring.

Topics: Alkaloids; Angiogenesis Inhibitors; Animals; Aquatic Organisms; Cyclization; Heterocyclic Compounds, 4 or More Rings; Isoquinolines; Ketones; Neovascularization, Pathologic; Neovascularization, Physiologic; Neuropeptides; Polycyclic Compounds; Porifera; Stereoisomerism; Steroids

2011