coptisine has been researched along with palmatine in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.35) | 18.7374 |
| 1990's | 4 (8.70) | 18.2507 |
| 2000's | 16 (34.78) | 29.6817 |
| 2010's | 23 (50.00) | 24.3611 |
| 2020's | 1 (2.17) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, JH; Kim, YH; Lee, WS; Ryu, YB | 1 |
| Fang, XP; Li, D; Shuai, H; Wang, TZ; Xie, CK; Zhang, H | 1 |
| Kakizawa, S; Misaki, T; Ojima, M; Oshima, T; Sagara, K; Yoshizawa, H | 1 |
| Hatanaka, T; Kadota, S; Katayama, K; Koizumi, T; Namba, T; Sekiya, K; Toshinal, A | 1 |
| Ishida, S; Miki, H; Okamura, N; Ono, H; Ono, Y; Tanaka, T; Yagi, A; Yano, A | 1 |
| Ahn, YJ; Chae, SH; Choi, DH; Jeong, IH; Oh, JW | 1 |
| Chen, YR; Her, GR; Wen, KC | 1 |
| Kai, M; Kim, EI; Lee, MK; Shin, JS | 1 |
| Ahn, YJ; Lee, HS; Lee, SG; Park, IK; Park, JD | 1 |
| Hu, JP; Takahashi, N; Yamada, T | 1 |
| Iwasa, K; Lee, DU; Moriyasu, M; Turuo, T; Wiegrebe, W; Yamori, T | 1 |
| Lee, KS; Lee, MK; Lee, SS; Ro, JS | 1 |
| Wei, L; Yang, D; Zhou, H | 1 |
| Inada, A; Muto, N; Nakanishi, T; Ootaki, K; Shigeta, K; Tatemoto, H | 1 |
| Cheng, YY; Peng, MX; Wu, YJ | 1 |
| Sun, SW; Tseng, HM | 1 |
| Li, ZH; Qin, HL; Wang, P; Yang, JR | 1 |
| Chen, SJ; Huang, XP; Ma, KS; Qin, SY; Zhong, GY | 1 |
| Tang, YL; Wang, HQ; Zhao, DB | 1 |
| Liang, X; Ren, L; Xu, Q; Xue, X; Zhang, F | 1 |
| Ma, Y; Shi, R; Tan, B; Wang, T | 1 |
| Dostál, J; Grycová, L; Hulová, D; Kares, R; Lemière, F; Maier, L; Marek, R; Necas, M; Standara, S | 1 |
| Feng, J; Jin, Y; Liang, X; Liu, Y; Xiao, Y; Xue, X; Zhang, J; Zhang, X | 1 |
| Inoue, M; Mizukami, H; Suzuki, H; Tanabe, H | 1 |
| Geng, Z; Luo, W; Qu, X; Zhang, Y; Zheng, H | 1 |
| Hasada, K; Mizukami, H; Nagatsu, A; Nishimura, T; Sugimoto, N; Yamazaki, T; Yoshida, T | 1 |
| Gao, C; Jiang, J; Qiu, F; Tan, Y; Zhang, X | 1 |
| Du, LM; Wu, H; Zhang, LB | 1 |
| Chen, LQ; Ding, PL; Li, YG; Lu, Y | 1 |
| Chen, Z; Liu, L | 1 |
| Feng, W; Kong, J; Wang, Z; Zhang, Q; Zhu, J | 1 |
| Fan, G; Lai, XR; Luo, WZ; Tang, C; Yue, QH; Zhang, MY; Zhang, Y; Zhou, XD | 1 |
| He, K; Li, X; Liu, X; Wang, D; Yang, Y; Ye, X; Yi, J | 1 |
| Huang, QW; Li, XF; Su, J; Wang, J; Zhang, YL | 1 |
| Kang, J; Zhang, Y | 1 |
| Li, BC; Li, JX; Wang, JY; Wang, RL; Xiao, XH; Yan, D; Zhang, LL | 1 |
| Liu, JX; Ma, ZT; Yang, XW; Zhang, Y | 1 |
| Bian, B; Han, L; Li, Y; Ren, W; Si, N; Wang, H; Wei, X; Xin, S; Yang, J; Zhao, H; Zuo, R | 1 |
| Du, LM; Feng, JX; Fu, YL; Li, CF; Li, Y; Liu, HL | 1 |
| Cai, F; Hu, P; Li, Y; Wang, Y; Zhang, H; Zhang, M | 1 |
| Kim, JH; Kim, OS; Seo, CS; Shin, HK | 1 |
| Bai, M; Jiang, H; Li, L; Song, F; Sun, S; Weng, Y; Zeng, S; Zhou, H; Zhou, S | 1 |
| Seo, CS; Shin, HK | 1 |
| Cong, H; Deng, S; Huo, X; Sun, C; Wang, C; Wang, Y; Wu, B; Xiang, T; Zhang, B; Zhang, H; Zhang, L; Zhao, X; Zheng, L | 1 |
| Jiang, Y; Li, HJ; Li, P; Lu, J; Ni, H; Wu, TJ | 1 |
| Cheng, J; Feng, J; Feng, S; Ma, C; Song, W; Wang, R; Xie, L; Zhang, X; Zhao, W | 1 |
46 other study(ies) available for coptisine and palmatine
| Article | Year |
|---|---|
Neuraminidase inhibitory activities of quaternary isoquinoline alkaloids from Corydalis turtschaninovii rhizome.
Topics: Alkaloids; Anti-Bacterial Agents; Clostridium Infections; Clostridium perfringens; Corydalis; Enzyme Inhibitors; Humans; Isoquinolines; Molecular Docking Simulation; Neuraminidase; Rhizome | 2014 |
[Quantitative determination of 5 alkaloids in plants of Coptis from China].
Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, Thin Layer; Densitometry; Drugs, Chinese Herbal; Triterpenes | 1989 |
Simultaneous determination of berberine, palmatine and coptisine in crude drugs and oriental pharmaceutical preparations by ion-pair high-performance liquid chromatography.
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Medicine, East Asian Traditional | 1982 |
[Study on baths with crude drug. II.: the effects of coptidis rhizoma extracts as skin permeation enhancer].
Topics: Animals; Baths; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Fluorouracil; In Vitro Techniques; Male; Rats; Rats, Wistar; Skin Absorption; Solubility; Stimulation, Chemical; Water | 1995 |
Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, berberine, coptisine, palmatine, jateorrhizine and glycyrrhizin in Kampo medicines by ion-pair high-performance liquid chromatography.
Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Glycyrrhizic Acid; Medicine, Kampo | 1999 |
Growth-inhibiting effects of Coptis japonica root-derived isoquinoline alkaloids on human intestinal bacteria.
Topics: Alkaloids; Bacteria; Berberine; Berberine Alkaloids; Humans; Intestinal Mucosa; Isoquinolines; Plant Extracts; Plant Roots | 1999 |
Analysis of coptisine, berberine and palmatine in adulterated Chinese medicine by capillary electrophoresis-electrospray ion trap mass spectrometry.
Topics: Berberine; Berberine Alkaloids; Drug Contamination; Electrophoresis, Capillary; Mass Spectrometry; Medicine, Chinese Traditional; Spectrophotometry, Ultraviolet | 2000 |
Inhibition of dopamine biosynthesis by protoberberine alkaloids in PC12 cells.
Topics: Animals; Berberine; Berberine Alkaloids; Calcium; Dopamine; Dopamine Antagonists; PC12 Cells; Rats; Tyrosine 3-Monooxygenase | 2000 |
Antifeeding activity of isoquinoline alkaloids identified in Coptis japonica roots against Hyphantria cunea (Lepidoptera: Arctiidae) and Agelastica coerulea (Coleoptera: Galerucinae).
Topics: Animals; Berberine; Berberine Alkaloids; Coleoptera; Feeding Behavior; Isoquinolines; Molecular Structure; Moths; Plant Roots; Plants, Medicinal | 2000 |
Coptidis rhizoma inhibits growth and proteases of oral bacteria.
Topics: Actinomyces; Aggregatibacter actinomycetemcomitans; Anti-Infective Agents; Bacteria; Berberine; Berberine Alkaloids; Coptis chinensis; Drugs, Chinese Herbal; Humans; Lactobacillus; Lethal Dose 50; Matrix Metalloproteinase Inhibitors; Microbial Sensitivity Tests; Mouth; Prevotella intermedia; Prevotella nigrescens; Protease Inhibitors; Ranunculaceae; Streptococcus | 2000 |
In vitro cytotoxicity of the protoberberine-type alkaloids.
Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Berberine Alkaloids; Brain Neoplasms; Breast Neoplasms; Colonic Neoplasms; Crystallography, X-Ray; Databases, Factual; Doxorubicin; Female; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mice; Mitomycin; Molecular Structure; Ovarian Neoplasms; Papaver; Plants, Medicinal; Stomach Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured | 2001 |
Inhibition of type A monoamine oxidase by coptisine in mouse brain.
Topics: Animals; Berberine; Berberine Alkaloids; Binding, Competitive; Brain; Clorgyline; Dialysis; Dose-Response Relationship, Drug; Iproniazid; Kynuramine; Male; Mice; Mice, Inbred ICR; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship | 2001 |
[Determination of alkaloids in Coptis-Cinnamomum compatibility by capillary electrophoresis].
Topics: Alkaloids; Berberine; Berberine Alkaloids; Cinnamomum; Coptis; Drug Combinations; Drugs, Chinese Herbal; Electrophoresis, Capillary; Plants, Medicinal | 1999 |
Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by a Coptidis Rhizoma extract and protoberberine alkaloids.
Topics: Animals; Berberine; Berberine Alkaloids; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Coptis chinensis; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Enzyme Activation; Nerve Growth Factors; Neurites; PC12 Cells; Rats | 2002 |
[Study on the solubility changes of Rhizoma Coptidis' main chemical constituents influenced by the proportion of Rhizoma Coptidis and Fructus Evodiae].
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drug Combinations; Drugs, Chinese Herbal; Evodia; Plant Roots; Plants, Medicinal; Solubility | 2003 |
Improved detection of Coptidis alkaloids by field-amplified sample stacking in capillary electrophoresis.
Topics: Alkaloids; Berberine; Berberine Alkaloids; Coptis; Coptis chinensis; Drugs, Chinese Herbal; Electrophoresis, Capillary; Reference Standards; Reproducibility of Results; Rhizome; Sensitivity and Specificity | 2004 |
[Establishment of the control substance of plant drug and fingerprints of Coptis chinensis].
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Magnetic Resonance Spectroscopy; Plants, Medicinal; Quality Control | 2004 |
[Quality assessment of Coptis chinensis in China].
Topics: Alkaloids; Berberine; Berberine Alkaloids; China; Chromatography, High Pressure Liquid; Coptis; Ecosystem; Plants, Medicinal; Quality Control; Spectrophotometry, Ultraviolet | 2005 |
[Studies on the alkaloids from herb of Corydalis adunca].
Topics: Berberine; Berberine Alkaloids; Corydalis; Plants, Medicinal | 2005 |
High performance liquid chromatography-mass spectrometry analysis of protoberberine alkaloids in medicine herbs.
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis chinensis; Drugs, Chinese Herbal; Mass Spectrometry; Molecular Structure; Phellodendron | 2007 |
Simultaneous quantification of three alkaloids of Coptidis Rhizoma in rat urine by high-performance liquid chromatography: application to pharmacokinetic study.
Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Female; Male; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Rhizome | 2007 |
Covalent bonding of azoles to quaternary protoberberine alkaloids.
Topics: Alkaloids; Azoles; Berberine; Berberine Alkaloids; Chemistry, Organic; Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Mass Spectrometry | 2008 |
Purification of alkaloids from Corydalis yanhusuo W. T. Wang using preparative 2-D HPLC.
Topics: 1-Butanol; Acetates; Acetonitriles; Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Corydalis; Mass Spectrometry | 2009 |
Selective regulation of multidrug resistance protein in vascular smooth muscle cells by the isoquinoline alkaloid coptisine.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Berberine; Berberine Alkaloids; Cardiovascular Agents; Cell Line; Cell Line, Tumor; Coptis; Dactinomycin; Drug Resistance, Multiple; Gene Expression Regulation; Genes, MDR; Humans; Membrane Transport Proteins; Mice; Molecular Structure; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rhodamines; RNA, Messenger; Up-Regulation | 2010 |
[Simultaneous determination of six alkaloids in Coptis chinensis of different regions by RP-HPLC].
Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal | 2010 |
Application of 1H-NMR spectroscopy to validation of berberine alkaloid reagents and to chemical evaluation of Coptidis Rhizoma.
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Extracts | 2011 |
Intestinal absorption mechanisms of berberine, palmatine, jateorhizine, and coptisine: involvement of P-glycoprotein.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Berberine; Berberine Alkaloids; Biological Transport; Caco-2 Cells; Cyclosporine; Drugs, Chinese Herbal; Humans; Intestinal Absorption; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Propionates; Quinolines; Verapamil | 2011 |
Ionic liquid sensitized fluorescence determination of four isoquinoline alkaloids.
Topics: Alkaloids; Berberine; Berberine Alkaloids; Ionic Liquids; Isoquinolines; Temperature | 2011 |
Determination of protoberberine alkaloids in Rhizoma Coptidis by ERETIC ¹H NMR method.
Topics: Berberine; Berberine Alkaloids; Coptis; Limit of Detection; Magnetic Resonance Spectroscopy | 2012 |
Analysis of four alkaloids of Coptis chinensis in rat plasma by high performance liquid chromatography with electrochemical detection.
Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Calibration; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Coptis; Coptis chinensis; Drugs, Chinese Herbal; Electrochemical Techniques; Electrodes; Limit of Detection; Rats | 2012 |
[Quantitative analysis of four alkaloids in Xianglian preparations by QAMS method].
Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Evaluation Studies as Topic; Quality Control; Reference Standards | 2011 |
Quality evaluation and species differentiation of Rhizoma coptidis by using proton nuclear magnetic resonance spectroscopy.
Topics: Berberine; Berberine Alkaloids; Coptis; Drugs, Chinese Herbal; Magnetic Resonance Spectroscopy; Multivariate Analysis; Plant Extracts; Principal Component Analysis; Rhizome; Species Specificity | 2012 |
Safety evaluation of main alkaloids from Rhizoma Coptidis.
Topics: 3T3-L1 Cells; Alkaloids; Animals; Berberine; Berberine Alkaloids; Blood Proteins; Body Weight; Coptis; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Hep G2 Cells; Humans; Inhibitory Concentration 50; Lethal Dose 50; Male; Mice; Organ Size; Rats; Rats, Sprague-Dawley; Rhizome | 2013 |
[Classification study of Coptis chinensis based on quantitative physical property characteristics of appearance and internal quality evaluation].
Topics: Berberine; Berberine Alkaloids; Coptis; Drugs, Chinese Herbal; Quality Control | 2012 |
[Screening of the active ingredients in natural products by capillary electrophoresis and high performance liquid chromatography-mass spectrometry].
Topics: Acetylcholinesterase; Alkaloids; Berberine; Berberine Alkaloids; Biological Products; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Electrophoresis, Capillary; Tandem Mass Spectrometry | 2013 |
[Microcalorimetric investigation on the interaction of six alkaloids from rhizoma coptidis].
Topics: Alkaloids; Berberine; Berberine Alkaloids; Coptis; Drug Interactions; Drug Synergism; Plants, Medicinal; Quality Control; Rhizome; Shigella dysenteriae | 2013 |
Pharmacochemistry and integrated pharmacokinetics of six alkaloids after oral administration of huang-lian-jie-du-tang decoction.
Topics: Administration, Oral; Alkaloids; Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Iridoids; Molecular Structure; Rats; Rats, Sprague-Dawley | 2014 |
Metabolic profiling analysis of berberine, palmatine, jatrorrhizine, coptisine and epiberberine in zebrafish by ultra-high performance liquid chromatography coupled with LTQ Orbitrap mass spectrometer.
Topics: Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Metabolomics; Models, Animal; Tandem Mass Spectrometry; Zebrafish | 2015 |
A competitive strategy based on cucurbit[7]uril supramolecular interaction for simple and sensitive detection of dibucaine.
Topics: Anesthetics, Local; Berberine; Berberine Alkaloids; Binding, Competitive; Bridged-Ring Compounds; Dibucaine; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Limit of Detection; Solutions; Spectrometry, Fluorescence; Thermodynamics | 2015 |
Two-stage fractionation of polar alkaloids from Rhizoma coptidis by countercurrent chromatography considering the strategy of reactive extraction.
Topics: Alkaloids; Berberine; Berberine Alkaloids; Chemical Fractionation; Countercurrent Distribution; Drugs, Chinese Herbal; Plants, Medicinal; Ranunculaceae | 2015 |
Simultaneous quantification and antiatherosclerosis effect of the traditional Korean medicine, Hwangryunhaedok-tang.
Topics: Animals; Antioxidants; Atherosclerosis; Berberine; Berberine Alkaloids; Biphenyl Compounds; Cell Proliferation; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Flavonoids; Gardenia; Iridoids; Lipoproteins, LDL; Medicine, Korean Traditional; Muscle, Smooth, Vascular; Phellodendron; Phytotherapy; Picrates; Platelet-Derived Growth Factor; Rats; Regression Analysis; Scutellaria | 2015 |
Interaction of six protoberberine alkaloids with human organic cation transporters 1, 2 and 3.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Berberine; Berberine Alkaloids; Cells, Cultured; Chromatography, Liquid; Dogs; Humans; Inhibitory Concentration 50; Madin Darby Canine Kidney Cells; Octamer Transcription Factor-3; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Polymorphism, Genetic; Tandem Mass Spectrometry | 2016 |
HPLC-PDA Method for Simultaneous Determination of Nine Marker Components in Banhasasim-Tang.
Topics: Acetonitriles; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Glucosides; Glycyrrhizic Acid; Humans; Limit of Detection; Medicine, Korean Traditional; Observer Variation; Pinellia; Plants, Medicinal; Reproducibility of Results; Solvents; Trifluoroacetic Acid; Water | 2016 |
Comparative pharmacokinetics study of five alkaloids in rat plasma and related compound-herb interactions mechanism after oral administration of Shuanghua Baihe tablets.
Topics: Administration, Oral; Alkaloids; Animals; Berberine; Berberine Alkaloids; Chromatography, Liquid; Drugs, Chinese Herbal; Medicine, Chinese Traditional; Rats; Tablets; Tandem Mass Spectrometry | 2018 |
Construction of an optimized method for quality evaluation and species discrimination of Coptidis Rhizoma by ion-pair high performance liquid chromatography combined with response surface methodology.
Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Ions; Reference Standards; Rhizome | 2018 |
Biological Response Profiling Reveals the Functional Differences of Main Alkaloids in Rhizoma Coptidis.
Topics: 3T3-L1 Cells; Animals; Berberine; Berberine Alkaloids; Cell Cycle; Cell Proliferation; Chromatography, High Pressure Liquid; Coptis; Coptis chinensis; Drugs, Chinese Herbal; Gene Expression Regulation; Hep G2 Cells; Humans; Mice; RAW 264.7 Cells; Rhizome; Signal Transduction; Transcriptome | 2021 |