Page last updated: 2024-08-24

coproporphyrin i and cyclosporine

coproporphyrin i has been researched along with cyclosporine in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (66.67)	24.3611
2020's	1 (33.33)	2.80

Authors

Authors	Studies
Chen, W; Cheng, Y; Dai, J; Freeden, C; Humphreys, WG; Lai, Y; Liu, T; Marathe, P; Shen, H; Zhang, Y	1
Brian, W; Giacomini, KM; Giacomini, MM; Horng, H; Humphreys, WG; Kroetz, DL; Lai, Y; Shen, H; Yee, SW	1
Fancher, RM; Gan, J; Gu, X; Hong, Y; Lai, Y; Shen, H; Sinz, M; Tian, Y; Wang, L	1

Trials

1 trial(s) available for coproporphyrin i and cyclosporine

Article	Year
Organic Anion Transporter Polypeptide 1B1 Polymorphism Modulates the Extent of Drug-Drug Interaction and Associated Biomarker Levels in Healthy Volunteers. Clinical and translational science, 2019, Volume: 12, Issue:4 Topics: Alleles; Area Under Curve; Biomarkers; Coproporphyrins; Cyclosporine; Drug Interactions; Female; Healthy Volunteers; Heterozygote; Humans; Liver-Specific Organic Anion Transporter 1; Male; Polymorphism, Single Nucleotide; Pravastatin	2019

Article

Year

Organic Anion Transporter Polypeptide 1B1 Polymorphism Modulates the Extent of Drug-Drug Interaction and Associated Biomarker Levels in Healthy Volunteers.

Clinical and translational science, 2019, Volume: 12, Issue:4

Topics: Alleles; Area Under Curve; Biomarkers; Coproporphyrins; Cyclosporine; Drug Interactions; Female; Healthy Volunteers; Heterozygote; Humans; Liver-Specific Organic Anion Transporter 1; Male; Polymorphism, Single Nucleotide; Pravastatin

2019

Other Studies

2 other study(ies) available for coproporphyrin i and cyclosporine

Article	Year
Coproporphyrins I and III as Functional Markers of OATP1B Activity: In Vitro and In Vivo Evaluation in Preclinical Species. The Journal of pharmacology and experimental therapeutics, 2016, Volume: 357, Issue:2 Topics: Animals; Area Under Curve; Coproporphyrins; Cyclosporine; HEK293 Cells; Hepatocytes; Humans; Liver-Specific Organic Anion Transporter 1; Macaca fascicularis; Mice; Mice, Knockout; Organic Anion Transporters; Rifampin; Rosuvastatin Calcium	2016
Absorption and Disposition of Coproporphyrin I (CPI) in Cynomolgus Monkeys and Mice: Pharmacokinetic Evidence to Support the Use of CPI to Inform the Potential for Organic Anion-Transporting Polypeptide Inhibition. Drug metabolism and disposition: the biological fate of chemicals, 2020, Volume: 48, Issue:8 Topics: Administration, Intravenous; Administration, Oral; Animals; Area Under Curve; Biological Availability; Biomarkers; Coproporphyrins; Cyclosporine; Drug Evaluation, Preclinical; Drug Interactions; Half-Life; Intestinal Absorption; Kidney; Liver; Liver-Specific Organic Anion Transporter 1; Macaca fascicularis; Male; Mice; Rifampin; Tissue Distribution	2020

Article

Year

Coproporphyrins I and III as Functional Markers of OATP1B Activity: In Vitro and In Vivo Evaluation in Preclinical Species.

The Journal of pharmacology and experimental therapeutics, 2016, Volume: 357, Issue:2

Topics: Animals; Area Under Curve; Coproporphyrins; Cyclosporine; HEK293 Cells; Hepatocytes; Humans; Liver-Specific Organic Anion Transporter 1; Macaca fascicularis; Mice; Mice, Knockout; Organic Anion Transporters; Rifampin; Rosuvastatin Calcium

2016

Absorption and Disposition of Coproporphyrin I (CPI) in Cynomolgus Monkeys and Mice: Pharmacokinetic Evidence to Support the Use of CPI to Inform the Potential for Organic Anion-Transporting Polypeptide Inhibition.

Drug metabolism and disposition: the biological fate of chemicals, 2020, Volume: 48, Issue:8

Topics: Administration, Intravenous; Administration, Oral; Animals; Area Under Curve; Biological Availability; Biomarkers; Coproporphyrins; Cyclosporine; Drug Evaluation, Preclinical; Drug Interactions; Half-Life; Intestinal Absorption; Kidney; Liver; Liver-Specific Organic Anion Transporter 1; Macaca fascicularis; Male; Mice; Rifampin; Tissue Distribution

2020