coprine and disulfiram
coprine has been researched along with disulfiram in 8 studies
Compound Research Comparison
| Studies (coprine) | Trials (coprine) | Recent Studies (post-2010) (coprine) | Studies (disulfiram) | Trials (disulfiram) | Recent Studies (post-2010) (disulfiram) |
|---|---|---|---|---|---|
| 16 | 0 | 2 | 3,776 | 175 | 723 |
Protein Interaction Comparison
| Protein | Taxonomy | coprine (IC50) | disulfiram (IC50) |
|---|---|---|---|
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | 10.1 | |
| Spike glycoprotein | Betacoronavirus England 1 | 9.35 | |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | 9.35 | |
| type-1 angiotensin II receptor | Homo sapiens (human) | 6.637 | |
| perilipin-5 | Homo sapiens (human) | 1.622 | |
| perilipin-1 | Homo sapiens (human) | 6.959 | |
| apelin receptor | Homo sapiens (human) | 2.63 | |
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | 4.2905 | |
| bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase | Mycobacterium tuberculosis H37Rv | 85.03 | |
| Transmembrane protease serine 2 | Homo sapiens (human) | 9.35 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Carbamate kinase | Giardia intestinalis | 0.6 | |
| Retinal dehydrogenase 1 | Homo sapiens (human) | 0.13 | |
| Aldehyde dehydrogenase, mitochondrial | Homo sapiens (human) | 3.4 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 4 | |
| Procathepsin L | Homo sapiens (human) | 9.35 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 4.904 | |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | 1.3756 | |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | 9.35 | |
| Replicase polyprotein 1ab | Human coronavirus 229E | 9.35 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | 9.35 | |
| Adenosine receptor A3 | Homo sapiens (human) | 0.356 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 6.9171 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.356 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 3.218 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 2.158 | |
| D(4) dopamine receptor | Homo sapiens (human) | 3.15 | |
| C-X-C chemokine receptor type 2 | Homo sapiens (human) | 6.013 | |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | 1.51 | |
| Protein-lysine 6-oxidase | Homo sapiens (human) | 0.32 | |
| Lysine-specific demethylase 5A | Homo sapiens (human) | 10 | |
| Caspase-1 | Homo sapiens (human) | 1.8 | |
| Mu-type opioid receptor | Homo sapiens (human) | 3.511 | |
| D(3) dopamine receptor | Homo sapiens (human) | 1.084 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 6.103 | |
| C-C chemokine receptor type 2 | Homo sapiens (human) | 2.468 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.356 | |
| C-C chemokine receptor type 4 | Homo sapiens (human) | 8.395 | |
| Gasdermin-D | Homo sapiens (human) | 0.4 | |
| Lysyl oxidase homolog 3 | Homo sapiens (human) | 0.093 | |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | 9.35 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 4.637 | |
| NACHT, LRR and PYD domains-containing protein 3 | Mus musculus (house mouse) | 3 | |
| Lysyl oxidase homolog 4 | Homo sapiens (human) | 0.059 | |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | 0.6 | |
| Monoglyceride lipase | Homo sapiens (human) | 0.8095 | |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | 9.35 | |
| Gasdermin-D | Mus musculus (house mouse) | 0.4 | |
| Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | 1.6 | |
| Lysyl oxidase homolog 2 | Homo sapiens (human) | 0.15 | |
| large T antigen | Betapolyomavirus macacae | 10.73 |
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Nilsson, GE; Tottmar, O; Wahlström, G | 1 |
| Nilsson, GE; Tottmar, O | 2 |
| Helander, A; Tottmar, O | 1 |
| Fried, R | 1 |
| Pettersson, H; Tottmar, O | 1 |
| Hellström, E; Tottmar, O | 1 |
| Kamijo, Y | 1 |
Reviews
2 review(s) available for coprine and disulfiram
| Article | Year |
|---|---|
Biochemical actions of anti-alcoholic agents.
Topics: Alcoholism; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Behavior; Carbon Disulfide; Cyanamide; Diethylamines; Disulfiram; Ditiocarb; Drug Implants; Glutamine; Humans; Metronidazole | 1980 |
[Clinical toxicology of mushroom poisoning. Clitocybe clavipes, Coprinopsis atramentarius].
Topics: Agaricales; Alcohol Deterrents; Aldehyde Oxidoreductases; Antiemetics; Disulfiram; Fluid Therapy; Glutamine; Humans; Infusions, Intravenous; Metoclopramide; Mushroom Poisoning | 2013 |
Other Studies
6 other study(ies) available for coprine and disulfiram
| Article | Year |
|---|---|
Effects of aldehyde dehydrogenase inhibitors on hexobarbital sensitivity and neuroamine metabolism in rat brain.
Topics: Aldehyde Oxidoreductases; Animals; Biogenic Amines; Brain Chemistry; Disulfiram; Dopamine; Drug Interactions; Glutamine; Hexobarbital; Hydroxyindoleacetic Acid; Male; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin | 1987 |
Effects of biogenic aldehydes and aldehyde dehydrogenase inhibitors on rat brain tryptophan hydroxylase activity in vitro.
Topics: Aldehyde Dehydrogenase; Aldehydes; Animals; Brain Stem; Cyclopropanes; Disulfiram; Ditiocarb; Glutamine; Hydroxyindoleacetic Acid; Indoles; Male; Rats; Rats, Inbred Strains; Tyrosine 3-Monooxygenase | 1987 |
Effects of disulfiram and coprine on rat brain tryptophan hydroxylation in vivo.
Topics: 5-Hydroxytryptophan; Age Factors; Aldehyde Dehydrogenase; Aldehydes; Animals; Brain; Disulfiram; Glutamine; Hydroxyindoleacetic Acid; Male; Rats; Rats, Inbred Strains; Serotonin; Tryptophan Hydroxylase | 1989 |
Effects of disulfiram, cyanamide and 1-aminocyclopropanol on the aldehyde dehydrogenase activity in human erythrocytes and leukocytes.
Topics: Aldehyde Dehydrogenase; Cyanamide; Cyanides; Cyclopropanes; Disulfiram; Ditiocarb; Erythrocytes; Glutamine; Humans; Leukocytes | 1988 |
Inhibition of aldehyde dehydrogenases in rat brain and liver by disulfiram and coprine.
Topics: Aldehyde Oxidoreductases; Animals; Brain; Disulfiram; Female; Glutamine; Kinetics; Mitochondria; Mitochondria, Liver; Rats; Rats, Inbred Strains; Substrate Specificity | 1982 |
Effects of aldehyde dehydrogenase inhibitors on enzymes involved in the metabolism of biogenic aldehydes in rat liver and brain.
Topics: Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Aldehydes; Animals; Brain; Cyanamide; Disulfiram; Ethanol; Female; Glutamine; Kinetics; Liver; Rats; Rats, Inbred Strains | 1982 |