Page last updated: 2024-09-04

conivaptan and bumetanide

conivaptan has been researched along with bumetanide in 4 studies

Compound Research Comparison

Studies (conivaptan)	Trials (conivaptan)	Recent Studies (post-2010) (conivaptan)	Studies (bumetanide)	Trials (bumetanide)	Recent Studies (post-2010) (bumetanide)
188	17	64	2,033	150	354

Protein Interaction Comparison

Protein	Taxonomy	conivaptan (IC50)	bumetanide (IC50)
Solute carrier family 12 member 2	Homo sapiens (human)		0.8

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (25.00)	29.6817
2010's	3 (75.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Kahle, KT; Simard, JM; Walcott, BP	1

Reviews

2 review(s) available for conivaptan and bumetanide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Novel treatment targets for cerebral edema. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2012, Volume: 9, Issue:1 Topics: Antidiuretic Hormone Receptor Antagonists; ATP-Binding Cassette Transporters; Benzazepines; Brain Edema; Bumetanide; Cerebral Cortex; Humans; Nervous System Diseases; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Sulfonylurea Receptors	2012

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Novel treatment targets for cerebral edema.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2012, Volume: 9, Issue:1

Topics: Antidiuretic Hormone Receptor Antagonists; ATP-Binding Cassette Transporters; Benzazepines; Brain Edema; Bumetanide; Cerebral Cortex; Humans; Nervous System Diseases; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Sulfonylurea Receptors

2012

Other Studies

2 other study(ies) available for conivaptan and bumetanide

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010