concanavalin-a and dimethyl-disulfide

concanavalin-a has been researched along with dimethyl-disulfide* in 1 studies

Other Studies

1 other study(ies) available for concanavalin-a and dimethyl-disulfide

Article	Year
Selective and reversible reduction of odor sensitivity in the rat by concanavalin A. Physiology & behavior, 1998, Dec-01, Volume: 65, Issue:3 Rats were trained using an olfactometer to detect low concentrations of ethyl acetate (EA) or dimethyl disulphide vapor (DMDS). Concanavalin A (ConA) applied to the olfactory mucosa had no effect on ability of rats to detect low concentrations of EA but produced a marked deficit in detection in DMDS. DMDS detection performance returned to control levels 3 days after the ConA treatment. These results provide the first behavioral evidence for odor-specific inhibition by chemical modification of the olfactory epithelium and support the notion that ConA selectively inactivates one or more types (subclasses) of olfactory receptor proteins. Topics: Acetates; Administration, Intranasal; Animals; Concanavalin A; Conditioning, Operant; Depression, Chemical; Disulfides; Dose-Response Relationship, Drug; Male; Odorants; Olfactory Mucosa; Rats; Rats, Wistar; Sensory Thresholds; Smell	1998

Article

Year

Selective and reversible reduction of odor sensitivity in the rat by concanavalin A.

Physiology & behavior, 1998, Dec-01, Volume: 65, Issue:3

Rats were trained using an olfactometer to detect low concentrations of ethyl acetate (EA) or dimethyl disulphide vapor (DMDS). Concanavalin A (ConA) applied to the olfactory mucosa had no effect on ability of rats to detect low concentrations of EA but produced a marked deficit in detection in DMDS. DMDS detection performance returned to control levels 3 days after the ConA treatment. These results provide the first behavioral evidence for odor-specific inhibition by chemical modification of the olfactory epithelium and support the notion that ConA selectively inactivates one or more types (subclasses) of olfactory receptor proteins.

Topics: Acetates; Administration, Intranasal; Animals; Concanavalin A; Conditioning, Operant; Depression, Chemical; Disulfides; Dose-Response Relationship, Drug; Male; Odorants; Olfactory Mucosa; Rats; Rats, Wistar; Sensory Thresholds; Smell

1998