concanavalin-a has been researched along with 2-(2-hydroxyethoxy)ethyl-methacrylate* in 1 studies
1 other study(ies) available for concanavalin-a and 2-(2-hydroxyethoxy)ethyl-methacrylate
| Article | Year |
|---|---|
One-pot synthesis of thermosensitive glycopolymers grafted gold nanoparticles and their lectin recognition.
Thermosensitive glucose-functionalized glycopolymers grafted gold nanoparticles (Glyco@GNPs) with good colloidal stability and thermosensitive in aqueous solution were fabricated by reversible addition-fragmentation chain transfer (RAFT) mediated one-pot synthesis. The formation of core-shell morphology with about a 60 nm gold core in diameter and a glycopolymer shell of about 80 nm in thickness was indicated by transmission electron microscopy (TEM). The recognition ability of the Glyco@GNPs toward lectin concannavalin A (Con A) was verified by ultraviolet-visible spectroscopy and dynamic light scattering (DLS). The good cytocompatibility of the glycopolymers and Glyco@GNPs was proven by MTT assay on L-929 cells. Glyco@GNPs could effectively inhibit hepatoma cells SMMC-7721 growth after recognizing Con A was also proved by MTT assay and flow cytometry assay. Topics: Animals; Cell Line; Cell Line, Tumor; Cell Survival; Chemistry Techniques, Synthetic; Concanavalin A; Fibroblasts; Glucose; Glycoconjugates; Gold; Hepatocytes; Hot Temperature; Humans; Metal Nanoparticles; Methacrylates; Mice; Polymerization; Solutions; Vinyl Compounds; Water | 2019 |