concanavalin-a and 1-((3-5-dichloro)-2-6-dihydroxy-4-methoxyphenyl)-1-hexanone

concanavalin-a has been researched along with 1-((3-5-dichloro)-2-6-dihydroxy-4-methoxyphenyl)-1-hexanone* in 1 studies

Other Studies

1 other study(ies) available for concanavalin-a and 1-((3-5-dichloro)-2-6-dihydroxy-4-methoxyphenyl)-1-hexanone

Article	Year
Isolation, Synthesis, and Biological Activity of Chlorinated Alkylresorcinols from Dictyostelium Cellular Slime Molds. Journal of natural products, 2017, 10-27, Volume: 80, Issue:10 Eight chlorinated alkylresorcinols, monochasiol A-H (1-8), were isolated from the fruiting bodies of Dictyostelium monochasioides. Compounds 1-8 were synthesized to confirm their structures and to obtain sufficient material for performing biological tests. Monochasiol A (1) selectively inhibited the concanavalin A-induced interleukin-2 production in Jurkat cells, a human T lymphocyte cell line. Monochasiols were biogenetically synthesized by the combination of biosynthetic enzymes relating to the principal polyketides, MPBD and DIF-1, produced by Dictyostelium discoideum. Topics: Cell Survival; Concanavalin A; Dictyosteliida; Dictyostelium; HeLa Cells; Hexanones; Humans; Hydrocarbons, Chlorinated; Interleukin-2; Jurkat Cells; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Polyketides; Resorcinols	2017

Article

Year

Isolation, Synthesis, and Biological Activity of Chlorinated Alkylresorcinols from Dictyostelium Cellular Slime Molds.

Journal of natural products, 2017, 10-27, Volume: 80, Issue:10

Eight chlorinated alkylresorcinols, monochasiol A-H (1-8), were isolated from the fruiting bodies of Dictyostelium monochasioides. Compounds 1-8 were synthesized to confirm their structures and to obtain sufficient material for performing biological tests. Monochasiol A (1) selectively inhibited the concanavalin A-induced interleukin-2 production in Jurkat cells, a human T lymphocyte cell line. Monochasiols were biogenetically synthesized by the combination of biosynthetic enzymes relating to the principal polyketides, MPBD and DIF-1, produced by Dictyostelium discoideum.

Topics: Cell Survival; Concanavalin A; Dictyosteliida; Dictyostelium; HeLa Cells; Hexanones; Humans; Hydrocarbons, Chlorinated; Interleukin-2; Jurkat Cells; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Polyketides; Resorcinols

2017