Page last updated: 2024-09-04

combretastatin b-1 and fosbretabulin

combretastatin b-1 has been researched along with fosbretabulin in 3 studies

Compound Research Comparison

Studies
(combretastatin b-1)
Trials
(combretastatin b-1)
Recent Studies (post-2010)
(combretastatin b-1)
Studies
(fosbretabulin)
Trials
(fosbretabulin)
Recent Studies (post-2010) (fosbretabulin)
8034970320
80358821310

Protein Interaction Comparison

ProteinTaxonomycombretastatin b-1 (IC50)fosbretabulin (IC50)
Tubulin polymerization-promoting proteinHomo sapiens (human)1.016
Tubulin alpha-1A chainSus scrofa (pig)1.82
Tubulin beta chainSus scrofa (pig)1.9428
Tubulin beta-4A chainHomo sapiens (human)1.663
Tubulin beta chainHomo sapiens (human)1.663
ATP-dependent translocase ABCB1Homo sapiens (human)0.009
Tubulin alpha-3C chainHomo sapiens (human)1.663
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)1.08
Delta-type opioid receptorMus musculus (house mouse)1.005
Delta-type opioid receptorRattus norvegicus (Norway rat)0.81
Mu-type opioid receptorMus musculus (house mouse)1.2
Tubulin alpha-1B chainHomo sapiens (human)1.663
Tubulin alpha-4A chainHomo sapiens (human)1.663
Tubulin beta-4B chainHomo sapiens (human)1.663
Vesicular acetylcholine transporterTetronarce californica (Pacific electric ray)1.8
Tubulin beta-3 chainHomo sapiens (human)1.5801
Tubulin beta-2A chainHomo sapiens (human)1.663
Beta-tubulin Leishmania donovani1.95
Tubulin beta-8 chainHomo sapiens (human)1.663
Tubulin beta-2B chainBos taurus (cattle)1.4484
Tubulin alpha-3E chainHomo sapiens (human)1.663
Tubulin alpha-1A chainHomo sapiens (human)1.663
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)1.4928
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)1.4037
Tubulin alpha-1C chainHomo sapiens (human)1.663
Tubulin beta-6 chainHomo sapiens (human)1.663
Tubulin beta-2B chainHomo sapiens (human)1.663
Tubulin beta-1 chainHomo sapiens (human)1.6366

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Boyd, MR; Chapuis, JC; Hamel, E; Herald, DL; Pettit, GR; Pettit, RK; Toki, BE1
Hamel, E; Herald, DL; Lippert, JW; Pettit, GR; Pettit, RK1
Bardakci, H; Genç, Y; Karatoprak, GŞ; Küpeli Akkol, E; Sobarzo-Sánchez, E; Yücel, Ç1

Reviews

1 review(s) available for combretastatin b-1 and fosbretabulin

ArticleYear
Combretastatins: An Overview of Structure, Probable Mechanisms of Action and Potential Applications.
    Molecules (Basel, Switzerland), 2020, May-31, Volume: 25, Issue:11

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Antiparasitic Agents; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Combretum; Drug Delivery Systems; HT29 Cells; Humans; Melanoma, Experimental; Solubility; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Water

2020

Other Studies

2 other study(ies) available for combretastatin b-1 and fosbretabulin

ArticleYear
Antineoplastic agents. 410. Asymmetric hydroxylation of trans-combretastatin A-4.
    Journal of medicinal chemistry, 1999, Apr-22, Volume: 42, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Bacteria; Biopolymers; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Fungi; Humans; Hydroxylation; Mice; Models, Molecular; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tubulin; Tumor Cells, Cultured

1999
Antineoplastic agents 440. Asymmetric synthesis and evaluation of the combretastatin A-1 SAR probes (1S,2S)- and (1R,2R)-1, 2-dihydroxy- 1-(2',3'-dihydroxy-4'-methoxyphenyl)-2-(3' ',4' ',5' '-trimethoxyphenyl)-ethane.
    Journal of natural products, 2000, Volume: 63, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Ethylene Glycols; Guaiacol; Humans; Mice; Microbial Sensitivity Tests; Molecular Probes; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Trees; Tumor Cells, Cultured

2000