Page last updated: 2024-08-26

combretastatin and triazoles

combretastatin has been researched along with triazoles in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (88.89)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Baraldi, PG; Basso, G; Bortolozzi, R; Brancale, A; Carrion, MD; Chen, L; Cruz-Lopez, O; Hamel, E; Lopez Cara, C; Romagnoli, R; Viola, G1
Aziz, G; Hansen, TV; Mathisen, GH; Odlo, K; Paulsen, RE1
Blokhin, DY; Chekhun, VF; Chernysheva, NB; Demchuk, DV; Firgang, SI; Kiselyov, AS; Konyushkin, LD; Kuiava, LM; Philchenkov, AA; Raihstat, MM; Samet, AV; Semenov, VV; Semenova, MN; Stashina, GA; Ushkarov, VI; Zavelevich, MP1
Kamal, A; Kapure, JS; Nagaraju, B; Nayak, VL; Prasad, B; Shaheer Malik, M; Shaik, B; Shaik, TB1
Alberto Marco, J; Carda, M; Díaz-Oltra, S; Falomir, E; Murga, J; Torijano-Gutiérrez, S; Vilanova, C1
Diao, PC; Li, Q; Li, YH; Yang, HK; You, WW; Zhang, B; Zhao, PL1
Bagul, C; Kamal, A; Lakshma Nayak, V; Shaik, SP; Shaik, TB; Srinivasa Reddy, T; Subba Rao, AV; Sunkari, S; Swapna, K1
Abdelhafez, EMN; Abdelhamid, D; Aly, OM; Gamal-Eldeen, AM; Ibrahim, MAA; Mustafa, M1
Abdelhafeez, DA; Aly, OM; Mustafa, M; Nofal, AE; Shatla, IM1

Other Studies

9 other study(ies) available for combretastatin and triazoles

ArticleYear
Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues.
    Journal of medicinal chemistry, 2010, May-27, Volume: 53, Issue:10

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Bibenzyls; Caspase 3; Cell Line, Tumor; Cell Shape; Cells, Cultured; Chick Embryo; Colchicine; Drug Screening Assays, Antitumor; Endothelial Cells; Enzyme Activation; G2 Phase; Humans; Membrane Potential, Mitochondrial; Mitochondria; Models, Molecular; Poly(ADP-ribose) Polymerases; Protein Binding; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators

2010
Combretastatin A-4 and structurally related triazole analogues induce caspase-3 and reactive oxygen species-dependent cell death in PC12 cells.
    European journal of pharmacology, 2013, Mar-05, Volume: 703, Issue:1-3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Caspase 3; Caspase 9; Cell Death; PC12 Cells; Rats; Reactive Oxygen Species; Triazoles

2013
Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines.
    Bioorganic & medicinal chemistry, 2014, Jan-15, Volume: 22, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bibenzyls; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Models, Animal; Molecular Conformation; Phenotype; Sea Urchins; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured

2014
Synthesis and biological evaluation of 1,2,3-triazole linked aminocombretastatin conjugates as mitochondrial mediated apoptosis inducers.
    Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19

    Topics: Antineoplastic Agents; Apoptosis; Bibenzyls; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; MCF-7 Cells; Mitochondria; Molecular Structure; Structure-Activity Relationship; Triazoles; Tubulin Modulators

2014
Design and synthesis of pironetin analogue/combretastatin A-4 hybrids containing a 1,2,3-triazole ring and evaluation of their cytotoxic activity.
    European journal of medicinal chemistry, 2014, Nov-24, Volume: 87

    Topics: Antineoplastic Agents, Phytogenic; Bibenzyls; Cell Proliferation; Cells, Cultured; Drug Design; Drug Screening Assays, Antitumor; Flow Cytometry; HEK293 Cells; Humans; Molecular Structure; Neoplasms; Pyrones; Structure-Activity Relationship; Triazoles

2014
Design, synthesis, and biological evaluation of novel alkylsulfanyl-1,2,4-triazoles as cis-restricted combretastatin A-4 analogues.
    European journal of medicinal chemistry, 2017, Jan-05, Volume: 125

    Topics: Antineoplastic Agents; Bibenzyls; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Neoplasms; Stereoisomerism; Structure-Activity Relationship; Triazoles

2017
Synthesis and biological evaluation of cis-restricted triazole/tetrazole mimics of combretastatin-benzothiazole hybrids as tubulin polymerization inhibitors and apoptosis inducers.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Benzothiazoles; Bibenzyls; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Molecular Docking Simulation; Molecular Structure; Polymerization; Stereoisomerism; Structure-Activity Relationship; Tetrazoles; Triazoles; Tubulin

2017
Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1,2,4-triazoles as potential combretastatin analogues.
    European journal of medicinal chemistry, 2017, Dec-01, Volume: 141

    Topics: Antineoplastic Agents; Bibenzyls; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Polymerization; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators; Tumor Cells, Cultured

2017
OMA1520 and OMA1774, novel 1,2,4-triazole bearing analogs of combretastatin A-4, inhibit hepatocellular carcinoma: Histological and immunohistochemical studies.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 138

    Topics: Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Carcinoma, Hepatocellular; Hep G2 Cells; HL-60 Cells; Humans; Liver Neoplasms, Experimental; Male; MCF-7 Cells; Molecular Docking Simulation; Rats; Triazoles

2021