Page last updated: 2024-08-26

combretastatin and stilbenes

combretastatin has been researched along with stilbenes in 92 studies

Research

Studies (92)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.17)	18.7374
1990's	14 (15.22)	18.2507
2000's	56 (60.87)	29.6817
2010's	16 (17.39)	24.3611
2020's	4 (4.35)	2.80

Authors

Authors	Studies
Chu, PS; Getahun, Z; Hamel, E; Jurd, L; Lin, CM	1
Chu, PS; Dempcy, RO; Hamel, E; Lin, CM; Pettit, GR; Schmidt, JM; Singh, SB	1
Hamel, E; Lin, CM	1
López, JL; Medarde, M; Peláez-Lamamié de Clairac, R; San Feliciano, A	1
Kajiyama, S; Kobayashi, A	1
Sackett, DL	1
Chaplin, DJ; Hill, SA; Parkins, CS; Pettit, GR	1
Day, BW; Hamel, E; Rosenkranz, HS; ter Haar, E	1
Bianchi, L; Faravelli, L; Guatteo, E; Pelizzoni, F; Rogers, CB; Verotta, L; Wanke, E	1
Bellini, B; Miglierini, G; Orsini, F; Pelizzoni, F	1
Breidahl, T; Horsman, MR; Maxwell, RJ; Nielsen, FU; Stødkilde-Jørgensen, H	1
Akiyama, Y; Fujita, K; Fukuda, Y; Hatanaka, T; Nakagawa, R; Nihei, Y; Ohsumi, K; Suga, Y; Tsuji, T	1
Aleksandrzak, K; Hadfield, JA; McGown, AT	1
Caballero, E; Feliciano, AS; Grávalos, DG; López, JL; Medarde, M; Peláez-Lamamié de Clairac, R; Ramos, AC	1
Caballero, E; del Rey, B; Inchaustti, A; Medarde, M; Ramos, AC; Rojas de Arias, A; San Feliciano, A; Yaluff, G	1
Couladouros, EA; Li, T; Moutsos, VI; Pitsinos, EN; Soufli, IC	1
Randal, J	1
Glass, TE; Johnson, RK; Kingston, DG; Mattern, MR; Schwikkard, S; Sharp, JL; Zhou, BN	1
Brown, ML; Macdonald, TL; Rieger, JM	1
Kovar, P; Ng, SC; Rosenberg, SH; Tahir, SK	1
Chaudhuri, AR; Hausheer, FH; Ludueña, RF; Schwarz, PM; Seetharamalu, P	1
Iwasaki, S; Shirai, R	1
Bailly, C; Lansiaux, A; Verdier-Pinard, P	1
Lodge, MA; Maxwell, RJ; Prise, VE; Rustin, GJ; Tozer, GM; Vojnovic, B; Wilson, J	1
Bentzen, S; Galbraith, SM; Lodge, MA; Padhani, AR; Rustin, GJ; Stirling, JJ; Taylor, NJ	1
Bane, SL; Janik, ME	1
Hill, SA; Kanthou, C; Parkins, CS; Tozer, GM	1
Ahn, BZ; Hong, DH; Kim, HM; Kim, Y; Nam, NH; You, YJ	1
Chang, CW; Chang, JY; Chang, YY; Chen, TW; Chern, SS; Hsieh, HP; Lin, CH; Lin, YT; Liou, JP; Mahindroo, N; Tan, UK; Wang, CC; Yang, YN	1
Lee, AE; McKeage, MJ; Pruijn, FB; Shalal-Zwain, S; Siim, BG; Wilson, WR	1
Prinz, H	1
Coy, DH; Fuselier, JA; Murphy, WA; Sun, L; Vasilevich, N; Woltering, SN	1
Collins, JM	1
Anderson, H; Folkes, LK; Galbraith, SM; Gumbrell, L; Price, PM; Rustin, GJ; Sena, L; Stratford, M	1
Akita, H; Hori, K; Kawaguchi, T; Saito, S; Sato, H; Sato, Y; Sugiyama, K	1
Gaukroger, K; Hadfield, JA; Lawrence, NJ; McGown, AT; Nolan, S	1
Mariani, SM	1
Cirla, A; Mann, J	1
Anthoney, DA; Bibby, MC; Cooper, PA; Kirwan, IG; Lippert, JW; Loadman, PM; Pettit, GR; Shnyder, SD; Swaine, DJ	1
Cavanaugh, SX; Hammond, LA; Thomas, CR	1
Kiziltepe, T; Sasisekharan, R; Sengupta, S	1
Ducki, S; Lawrence, NJ; Mackenzie, G; Snyder, JP	1
Maya, AB; Medarde, M; Pérez-Melero, C	1
Caballero, E; Medarde, M; Peláez, R; Pérez-Melero, C; Salvador, N; Sánchez Maya, AB	1
Charoenchai, P; Danwisetkanjana, K; Intamas, S; Kittakoop, P; Thebtaranonth, Y; Vongvanich, N	1
Bosmans, H; Chen, F; De Keyzer, F; Hermans, R; Landuyt, W; Marchal, G; Ni, Y; Thoeny, HC; Verbeken, EK	1
Bentzen, L; Bjørnerud, A; Briley-Saebø, K; Horsman, MR; Nielsen, T; Ostergaard, L; Overgaard, J; Vestergaard-Poulsen, P	1
Hsieh, HP; Liou, JP; Mahindroo, N	1
Gaukroger, K; Hadfield, JA; Hirst, N; Lawrence, NJ; McGown, AT; Weston, AP	1
Baguley, BC; Kanthou, C; Tozer, GM	1
Allegrone, G; Coggiola, B; Genazzani, AA; Pagliai, F; Tron, GC	1
Kiani, MF; Moore, BM; Nallamothu, R; Pattillo, CB; Sari-Sarraf, F; Wood, GC	1
Mooney, D	1
Capila, I; Eavarone, D; Kiziltepe, T; Sasisekharan, R; Sengupta, S; Watson, N; Zhao, G	1
Arman, H; Brown, T; Dickson, J; Harris, J; Holt, HL; LeBlanc, R; Lee, M; Pati, HN; Pennington, W; Stewart, M; VanDerveer, D	1
Erturk, SM	1
Cousin, D; Mann, J; Nieuwenhuyzen, M; van den Berg, H	1
Ackley, JF; Edvardsen, K; Garner, CM; Hadimani, MB; Monk, KA; Mugabe, BE; Pettit, GR; Pinney, KG; Rhodes, MR; Siles, R; Studerus, SW; Trawick, ML	1
Alloatti, D; Baruchello, R; Bucci, F; Carminati, P; Castorina, M; Giannini, G; Guglielmi, MB; Marcellini, M; Pavani, MG; Pisano, C; Riccioni, T; Rizzi, M; Romagnoli, R; Rondanin, R; Simoni, D	1
Beltrami, L; Busacca, S; Genazzani, AA; Imovilli, D; Massarotti, A; Miglio, G; Pagliai, F; Pirali, T; Sorba, G; Tron, GC; Verotta, L	1
Martin, S	1
Alvarez, C; Alvarez, R; Corchete, P; Medarde, M; Peláez, R; Pérez-Melero, C	1
Bajenaru, ML; Feuer, W; Fini, ME; Jockovich, ME; Murray, TG; Piña, Y; Suarez, F	1
López, V; Mateo, C; Medarde, M; Peláez, R	1
Byung-Zun, A; Nam, NH	1
Alvarez, R; Mateo, C; Medarde, M; Peláez, R; Pérez-Melero, C	1
Stratford, MR	1
Ackley, JF; Chaplin, DJ; Chapuis, JC; Edvardsen, K; Garner, CM; Guddneppanavar, R; Hadimani, MB; Hall, JJ; Monk, KA; Mugabe, BE; Pettit, GR; Pinney, KG; Siles, R; Trawick, ML	1
Alloatti, D; Cabri, W; Carminati, P; Ciacci, A; Gallo, G; Giannini, G; Guglielmi, MB; Lustrati, I; Marcellini, M; Marzi, M; Pisano, C; Riccioni, T; Tinti, MO	1
Burchill, SA; Dalal, S	1
Chapuis, JC; Hamel, E; Hogan, F; Moser, BR; Pettit, GR; Pettit, RK; Pon, S; Schmidt, JM; Wolf, S	1
Groy, TL; Herald, CL; Knight, JC; Melody, N; Pettit, GR; Thornhill, A	1
Hogan, F; Minardi, MD; Pettit, GR; Price, PM	1
Hua, R; Li, J; Liu, T	1
Cai, YC; Xian, LJ; Zou, Y	1
Babu, B; Brockway, O; Dandavati, A; Lee, M; Mooberry, SL; Satam, V; Sjoholm, R; Tzou, S; Westbrook, C; Zeller, M	1
Babu, B; Bandi, RK; Behera, AK; Brockway, O; Lee, M; Mishra, BK; Mooberry, SL; Pati, H; Satam, V; Tzou, S; Westbrook, C; Zeller, M	1
Bisby, RH; Botchway, SW; Hadfield, JA; McGown, AT; Parker, AW; Scherer, KM	1
Azzariti, A; Gnoni, A; Numico, G; Paradiso, A; Porcelli, L; Quatrale, AE	1
Chaplin, DJ; Garner, CM; Ghatak, A; Hadimani, MB; Hall, JJ; Hamel, E; Kessler, RJ; Liu, L; Lopez, R; Macdonough, MT; Mason, RP; Nguyen, BL; Pettit, GR; Pinney, KG; Shirali, AR; Sriram, M; Strecker, TE; Trawick, ML	1
Chang, HZ; Huang, DP; Huang, TK; Jiang, XQ; Lai, SS; Tang, WJ; Wang, L; Wei, XH; Xu, XD; Yang, RM; Zou, Y	1
Lipeeva, AV; Pokrovsky, AG; Pokrovsky, MA; Shakirov, MM; Shults, EE	1
Álvarez, R; López, V; Mateo, C; Medarde, M; Peláez, R	1
Jakubowska, J; Krawczyk, H; Książek, K; Mikuła-Pietrasik, J	1
Bao, K; Guan, Q; Guo, D; Jiang, M; Liu, C; Wu, Y; Xu, J; Yang, F; Zhang, W	1
Giacomini, E; Guidotti, L; Recanatini, M; Roberti, M; Rupiani, S	1
Aoshima, K; Hoshino, Y; Izumi, Y; Takagi, S	1
Bernasconi, L; Bisby, RH; Holzmann, N; Parker, AW	1
Elming, PB; Horsman, MR; Nielsen, PS; Wittenborn, TR	1
Kucinska, M; Murias, M; Pecyna, P; Wargula, J	1
Kankala, RK; Kankala, S; Nerella, S; Paidakula, S	1
Abourehab, MAS; Beshay, BY; Elbastawesy, MAI; Masoud, RE; Moustafa, AMY; Zakaria, MY; Zaki, I	1

Reviews

15 review(s) available for combretastatin and stilbenes

Article	Year
[Molecular basis of probes for cytoskeletal proteins]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1993, Volume: 38, Issue:11 Topics: Animals; Bibenzyls; Colchicine; Cytoskeletal Proteins; Fertilization; Microtubules; Mitosis; Paclitaxel; Sea Urchins; Stilbenes; Zearalenone	1993
Podophyllotoxin, steganacin and combretastatin: natural products that bind at the colchicine site of tubulin. Pharmacology & therapeutics, 1993, Volume: 59, Issue:2 Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Binding Sites; Cell Division; Lignans; Podophyllotoxin; Polymers; Stilbenes; Structure-Activity Relationship; Tubulin	1993
[Natural organic compounds that affect to microtubule functions: syntheses and structure-activity relationships of combretastatins, curacin A and their analogs as the colchicine-site ligands on tubulin]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2000, Volume: 120, Issue:10 Topics: Bibenzyls; Binding Sites; Cell Cycle; Colchicine; Cyclopropanes; Ligands; Microtubules; Protein Binding; Stilbenes; Structure-Activity Relationship; Thiazoles; Tubulin	2000
[Combretastatin A4 phosphate]. Bulletin du cancer, 2001, Volume: 88, Issue:3 Topics: Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Mice; Neoplasms; Neovascularization, Pathologic; Quantitative Structure-Activity Relationship; Rats; Stilbenes; Transplantation, Heterologous	2001
The biology of the combretastatins as tumour vascular targeting agents. International journal of experimental pathology, 2002, Volume: 83, Issue:1 Topics: Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Endothelium, Vascular; Humans; Neoplasms; Neovascularization, Pathologic; Stilbenes	2002
Recent advances in the field of tubulin polymerization inhibitors. Expert review of anticancer therapy, 2002, Volume: 2, Issue:6 Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bibenzyls; Biological Factors; Drug Design; Humans; Neoplasms; Protein Binding; Stilbenes; Tubulin; Tubulin Modulators	2002
Combretastatins: from natural products to drug discovery. Natural product reports, 2003, Volume: 20, Issue:6 Topics: Antineoplastic Agents, Phytogenic; Bibenzyls; Biological Products; Combretum; Molecular Structure; Plant Bark; South Africa; Stilbenes; Structure-Activity Relationship	2003
Naphthalene combretastatin analogues: synthesis, cytotoxicity and antitubulin activity. Journal of enzyme inhibition and medicinal chemistry, 2004, Volume: 19, Issue:6 Topics: Animals; Bibenzyls; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Naphthalenes; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators	2004
Pharmaceutical design of antimitotic agents based on combretastatins. Current pharmaceutical design, 2005, Volume: 11, Issue:13 Topics: Animals; Antineoplastic Agents; Bibenzyls; Clinical Trials as Topic; Drug Design; Humans; Stilbenes	2005
Disrupting tumour blood vessels. Nature reviews. Cancer, 2005, Volume: 5, Issue:6 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bibenzyls; Capillary Permeability; Clinical Trials as Topic; Endothelial Cells; Humans; Neoplasms; Neovascularization, Pathologic; Stilbenes; Xanthones	2005
[Advances in the study of the anti-tumor activity of small molecule vascular disrupting agents]. Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:3 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Bibenzyls; Diphosphates; Endothelial Cells; Humans; Molecular Structure; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Organophosphorus Compounds; Serine; Stilbenes; Tubulin Modulators; Xanthones	2010
New vascular disrupting agents in upper gastrointestinal malignancies. Current medicinal chemistry, 2014, Volume: 21, Issue:8 Topics: Angiogenesis Inhibitors; Animals; Bibenzyls; Diphosphates; Gastrointestinal Neoplasms; Humans; Neovascularization, Pathologic; Organophosphorus Compounds; Serine; Stilbenes; Upper Gastrointestinal Tract	2014
The Use of Stilbene Scaffold in Medicinal Chemistry and Multi- Target Drug Design. Current medicinal chemistry, 2016, Volume: 23, Issue:23 Topics: Alzheimer Disease; Antineoplastic Agents, Phytogenic; Bibenzyls; Chemistry, Pharmaceutical; Drug Design; Humans; Neoplasms; Resveratrol; Stilbenes; Structure-Activity Relationship	2016
More Than Resveratrol: New Insights into Stilbene-Based Compounds. Biomolecules, 2020, 07-27, Volume: 10, Issue:8 Topics: Animals; Bibenzyls; Drug Discovery; Humans; Resveratrol; Stilbenes	2020
Recent Trends in Tubulin-Binding Combretastatin A-4 Analogs for Anticancer Drug Development. Current medicinal chemistry, 2022, Volume: 29, Issue:21 Topics: Antineoplastic Agents; Bibenzyls; Cell Line, Tumor; Cell Proliferation; Drug Design; Humans; Neoplasms; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators	2022

Trials

1 trial(s) available for combretastatin and stilbenes

Article	Year
Phase I clinical trial of weekly combretastatin A4 phosphate: clinical and pharmacokinetic results. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Aug-01, Volume: 21, Issue:15 Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Area Under Curve; Bibenzyls; Chromatography, High Pressure Liquid; Drug Administration Schedule; Female; Humans; Infusion Pumps; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasms; Statistics, Nonparametric; Stilbenes; Tomography, Emission-Computed; Treatment Outcome	2003

Article

Year

Phase I clinical trial of weekly combretastatin A4 phosphate: clinical and pharmacokinetic results.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Aug-01, Volume: 21, Issue:15

Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Area Under Curve; Bibenzyls; Chromatography, High Pressure Liquid; Drug Administration Schedule; Female; Humans; Infusion Pumps; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasms; Statistics, Nonparametric; Stilbenes; Tomography, Emission-Computed; Treatment Outcome

2003

Other Studies

76 other study(ies) available for combretastatin and stilbenes

Article	Year
Synthesis of alkoxy-substituted diaryl compounds and correlation of ring separation with inhibition of tubulin polymerization: differential enhancement of inhibitory effects under suboptimal polymerization reaction conditions. Journal of medicinal chemistry, 1992, Mar-20, Volume: 35, Issue:6 Topics: Animals; Antineoplastic Agents; Bibenzyls; Binding Sites; Bridged-Ring Compounds; Colchicine; Leukemia L1210; Mice; Stilbenes; Structure-Activity Relationship; Tubulin	1992
Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study. Molecular pharmacology, 1988, Volume: 34, Issue:2 Topics: Animals; Anisoles; Antineoplastic Agents; Bibenzyls; Binding Sites; Binding, Competitive; Colchicine; Leukemia L1210; Mice; Mitosis; Podophyllotoxin; Protein Binding; Stilbenes; Structure-Activity Relationship; Tubulin	1988
Interactions of combretastatin, a new plant-derived antimitotic agent, with tubulin. Biochemical pharmacology, 1983, Dec-15, Volume: 32, Issue:24 Topics: Animals; Anisoles; Bibenzyls; Binding Sites; Brain Chemistry; Cattle; Cells, Cultured; Colchicine; Leukemia L1210; Mice; Mitosis; Protein Binding; Stilbenes; Tubulin	1983
A versatile approach to the synthesis of combretastatins. Journal of natural products, 1994, Volume: 57, Issue:8 Topics: Antineoplastic Agents, Phytogenic; Bibenzyls; Magnetic Resonance Spectroscopy; Spectrophotometry, Ultraviolet; Stilbenes	1994
Antivascular approaches to solid tumour therapy: evaluation of tubulin binding agents. The British journal of cancer. Supplement, 1996, Volume: 27 Topics: Animals; Antineoplastic Agents; Bibenzyls; Depsipeptides; Flavonoids; Mice; Mice, Inbred CBA; Neoplasms, Experimental; Oligopeptides; Regional Blood Flow; Stilbenes; Tirapazamine; Triazines; Tubulin; Tumor Necrosis Factor-alpha; Vinblastine	1996
Computational and molecular modeling evaluation of the structural basis for tubulin polymerization inhibition by colchicine site agents. Bioorganic & medicinal chemistry, 1996, Volume: 4, Issue:10 Topics: Antineoplastic Agents, Phytogenic; Bibenzyls; Binding Sites; Colchicine; Models, Molecular; Paclitaxel; Podophyllotoxin; Protein Conformation; Software; Stilbenes; Tubulin; Tubulin Modulators	1996
A novel K+ channel blocker isolated from 'hiccup nut' toxin. Neuroreport, 1996, Nov-04, Volume: 7, Issue:15-17 Topics: Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Dose-Response Relationship, Drug; Ganglia, Spinal; Humans; Potassium Channels; Rats; Stilbenes	1996
Synthesis of biologically active polyphenolic glycosides (combretastatin and resveratrol series). Carbohydrate research, 1997, Jun-20, Volume: 301, Issue:3-4 Topics: Antineoplastic Agents; Bibenzyls; Cell Division; Ganglia, Spinal; Glucosides; Glycosylation; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mitosis; Molecular Structure; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Tumor Cells, Cultured	1997
Effects of combretastatin on murine tumours monitored by 31P MRS, 1H MRS and 1H MRI. International journal of radiation oncology, biology, physics, 1998, Nov-01, Volume: 42, Issue:4 Topics: Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Drug Screening Assays, Antitumor; Energy Metabolism; Hydrogen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Animal; Mice; Necrosis; Phosphorus; Stilbenes	1998
Novel B-ring modified combretastatin analogues: syntheses and antineoplastic activity. Bioorganic & medicinal chemistry letters, 1998, Dec-01, Volume: 8, Issue:23 Topics: Antineoplastic Agents, Phytogenic; Bibenzyls; Drug Stability; Humans; Stilbenes; Structure-Activity Relationship	1998
Antimitotic activity of diaryl compounds with structural features resembling combretastatin A-4. Anti-cancer drugs, 1998, Volume: 9, Issue:6 Topics: Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Drug Screening Assays, Antitumor; Leukemia P388; Mice; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured	1998
Synthesis and pharmacological activity of diarylindole derivatives. Cytotoxic agents based on combretastatins. Bioorganic & medicinal chemistry letters, 1999, Aug-16, Volume: 9, Issue:16 Topics: Antineoplastic Agents, Phytogenic; Bibenzyls; Drug Screening Assays, Antitumor; Humans; Stilbenes; Tumor Cells, Cultured	1999
Leishmanicidal activity of combretastatin analogues and heteroanalogues. Bioorganic & medicinal chemistry letters, 1999, Sep-20, Volume: 9, Issue:18 Topics: Animals; Antiprotozoal Agents; Bibenzyls; Leishmania; Mice; Species Specificity; Stilbenes	1999
Stabilization of microtubules by Combretastatin D derivatives. Bioorganic & medicinal chemistry letters, 1999, Oct-18, Volume: 9, Issue:20 Topics: Bibenzyls; Microtubules; Molecular Structure; Stilbenes	1999
Antiangiogenesis drugs target specific cancers, mechanisms. Journal of the National Cancer Institute, 2000, Apr-05, Volume: 92, Issue:7 Topics: Angiostatins; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bibenzyls; Humans; Matrix Metalloproteinase Inhibitors; Neoplasms; Neovascularization, Pathologic; Peptide Fragments; Plasminogen; Stilbenes	2000
Bioactive compounds from Combretum erythrophyllum. Journal of natural products, 2000, Volume: 63, Issue:4 Topics: Antineoplastic Agents, Phytogenic; Bibenzyls; Carbohydrate Sequence; DNA Damage; DNA Repair; Drug Screening Assays, Antitumor; Glycosides; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Plant Extracts; Plants, Medicinal; South Africa; Spectrophotometry, Ultraviolet; Stilbenes; Tumor Cells, Cultured; Wood	2000
Comparative molecular field analysis of colchicine inhibition and tubulin polymerization for combretastatins binding to the colchicine binding site on beta-tubulin. Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:6 Topics: Bibenzyls; Binding Sites; Biopolymers; Colchicine; Molecular Conformation; Stilbenes; Tubulin	2000
Rapid colchicine competition-binding scintillation proximity assay using biotin-labeled tubulin. BioTechniques, 2000, Volume: 29, Issue:1 Topics: Aminophenols; Bibenzyls; Binding Sites; Binding, Competitive; Biotinylation; Colchicine; Demecolcine; Mebendazole; Microspheres; Podophyllotoxin; Scintillation Counting; Solvents; Stilbenes; Streptavidin; Sulfonamides; Tritium; Tubulin; Yttrium	2000
The interaction of the B-ring of colchicine with alpha-tubulin: a novel footprinting approach. Journal of molecular biology, 2000, Nov-10, Volume: 303, Issue:5 Topics: Amino Acid Sequence; Animals; Bibenzyls; Binding Sites; Cattle; Chromatography, High Pressure Liquid; Colchicine; Fluorescence; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Podophyllotoxin; Protein Conformation; Protein Footprinting; Stilbenes; Tropolone; Tryptophan; Tubulin; Urea	2000
Evaluation of the anti-vascular effects of combretastatin in rodent tumours by dynamic contrast enhanced MRI. NMR in biomedicine, 2002, Volume: 15, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Antipyrine; Bibenzyls; Carcinosarcoma; Contrast Media; Gadolinium DTPA; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Radionuclide Imaging; Rats; Stilbenes	2002
Reproducibility of dynamic contrast-enhanced MRI in human muscle and tumours: comparison of quantitative and semi-quantitative analysis. NMR in biomedicine, 2002, Volume: 15, Issue:2 Topics: Antineoplastic Agents; Bibenzyls; Contrast Media; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Muscle, Skeletal; Neoplasms; Reproducibility of Results; Stilbenes; Xanthenes; Xanthones	2002
Synthesis and antimicrotubule activity of combretatropone derivatives. Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:6 Topics: Antineoplastic Agents; Bibenzyls; Colchicine; Magnetic Resonance Spectroscopy; Microtubules; Molecular Structure; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators	2002
Synthesis and anti-tumor activity of novel combretastatins: combretocyclopentenones and related analogues. Bioorganic & medicinal chemistry letters, 2002, Aug-05, Volume: 12, Issue:15 Topics: Animals; Antineoplastic Agents; Bibenzyls; Carcinoma, Lewis Lung; Cyclopentanes; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Mice; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured	2002
Structure-activity and crystallographic analysis of benzophenone derivatives-the potential anticancer agents. Bioorganic & medicinal chemistry letters, 2003, Jan-06, Volume: 13, Issue:1 Topics: Antineoplastic Agents; Benzophenones; Bibenzyls; Cell Cycle; Crystallography, X-Ray; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured	2003
Marked potentiation of the antitumour activity of chemotherapeutic drugs by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA). Cancer chemotherapy and pharmacology, 2003, Volume: 51, Issue:1 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bibenzyls; Carboplatin; Dose-Response Relationship, Drug; Drug Synergism; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Paclitaxel; Stilbenes; Time Factors; Xanthenes; Xanthones	2003
An adjustable release rate linking strategy for cytotoxin-peptide conjugates. Bioorganic & medicinal chemistry letters, 2003, Mar-10, Volume: 13, Issue:5 Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Bibenzyls; Camptothecin; Carbamates; Cross-Linking Reagents; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Neuroblastoma; Peptides; Rats; Somatostatin; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured	2003
Functional imaging in phase I studies: decorations or decision making? Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Aug-01, Volume: 21, Issue:15 Topics: Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Clinical Trials, Phase I as Topic; Decision Making; Humans; Magnetic Resonance Imaging; Neoplasms; Rats; Stilbenes; Tomography, Emission-Computed	2003
Differential relationship between changes in tumour size and microcirculatory functions induced by therapy with an antivascular drug and with cytotoxic drugs. implications for the evaluation of therapeutic efficacy of AC7700 (AVE8062). European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:13 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bibenzyls; Blood Flow Velocity; Cell Division; Doxorubicin; Lung Neoplasms; Male; Microcirculation; Mitomycin; Neoplasm Transplantation; Rats; Stilbenes; Treatment Outcome	2003
Structural requirements for the interaction of combretastatins with tubulin: how important is the trimethoxy unit? Organic & biomolecular chemistry, 2003, Sep-07, Volume: 1, Issue:17 Topics: Animals; Antineoplastic Agents; Bibenzyls; Cell Line; Chlorocebus aethiops; Drug Screening Assays, Antitumor; Humans; Immunohistochemistry; Inhibitory Concentration 50; K562 Cells; Molecular Structure; Stilbenes; Structure-Activity Relationship; Tubulin; Vero Cells	2003
Anti-angiogenesis: the challenges ahead. MedGenMed : Medscape general medicine, 2003, Apr-30, Volume: 5, Issue:2 Topics: Angiogenesis Inhibitors; Angiogenic Proteins; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Bevacizumab; Bibenzyls; Biological Availability; Biomarkers; Carcinoma, Renal Cell; Clinical Trials as Topic; Combined Modality Therapy; Drug Resistance, Neoplasm; Endostatins; Endothelial Growth Factors; Endothelium, Vascular; Growth Inhibitors; Humans; Kidney Neoplasms; Microtubules; Neoplasms; Neovascularization, Pathologic; Ontario; Receptors, Vascular Endothelial Growth Factor; Stilbenes	2003
Comparative preclinical pharmacokinetic and metabolic studies of the combretastatin prodrugs combretastatin A4 phosphate and A1 phosphate. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Feb-15, Volume: 10, Issue:4 Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Area Under Curve; Bibenzyls; Calibration; Cell Line, Tumor; Chromatography; Chromatography, High Pressure Liquid; Coloring Agents; Female; Humans; Inhibitory Concentration 50; Mass Spectrometry; Mice; Models, Chemical; Phosphorylation; Prodrugs; Stilbenes; Tetrazolium Salts; Thiazoles; Time Factors	2004
An image worth a thousand lives? Nature biotechnology, 2004, Volume: 22, Issue:6 Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzoquinones; Bibenzyls; Diagnostic Imaging; Down-Regulation; ErbB Receptors; Gefitinib; Heterocyclic Compounds, 1-Ring; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Magnetic Resonance Imaging; Molecular Probe Techniques; Mutation; Neoplasms; Phthalazines; Physiological Phenomena; Positron-Emission Tomography; Protein Binding; Protein Kinase Inhibitors; Pyridines; Quinazolines; Receptor Protein-Tyrosine Kinases; Receptor, ErbB-2; Receptors, Vascular Endothelial Growth Factor; Rifabutin; Stilbenes; Tissue Distribution; Trastuzumab	2004
A dual-color fluorescence imaging-based system for the dissection of antiangiogenic and chemotherapeutic activity of molecules. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:13 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Bibenzyls; Cell Line, Tumor; Coculture Techniques; Doxorubicin; Extracellular Matrix; Fluorescence; Hepatocyte Growth Factor; Humans; Melanoma; Neoplasms; Neovascularization, Pathologic; Phthalazines; Pyridines; Stilbenes; Thalidomide; Vascular Endothelial Growth Factor A	2004
Quantitative structure-activity relationship (5D-QSAR) study of combretastatin-like analogues as inhibitors of tubulin assembly. Journal of medicinal chemistry, 2005, Jan-27, Volume: 48, Issue:2 Topics: Antineoplastic Agents; Bibenzyls; Binding Sites; Colchicine; Ligands; Models, Molecular; Molecular Conformation; Monte Carlo Method; Quantitative Structure-Activity Relationship; Stilbenes; Tubulin; Tubulin Modulators	2005
New naphthylcombretastatins. Modifications on the ethylene bridge. Bioorganic & medicinal chemistry, 2005, Mar-15, Volume: 13, Issue:6 Topics: Animals; Bibenzyls; Cattle; Ethylenes; Inhibitory Concentration 50; Molecular Structure; Naphthalenes; Stilbenes; Structure-Activity Relationship; Tubulin	2005
Combretastatins D-3 and D-4, new macrocyclic lactones from Getonia floribunda. Planta medica, 2005, Volume: 71, Issue:2 Topics: Antineoplastic Agents, Phytogenic; Antitubercular Agents; Bibenzyls; Cell Line, Tumor; Combretaceae; Humans; Inhibitory Concentration 50; Lactams, Macrocyclic; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phytotherapy; Plant Extracts; Stilbenes	2005
Diffusion-weighted MR imaging in monitoring the effect of a vascular targeting agent on rhabdomyosarcoma in rats. Radiology, 2005, Volume: 234, Issue:3 Topics: Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Contrast Media; Diffusion Magnetic Resonance Imaging; Gadolinium DTPA; Image Processing, Computer-Assisted; Injections, Intraperitoneal; Male; Rats; Rhabdomyosarcoma; Stilbenes	2005
Intravascular contrast agent-enhanced MRI measuring contrast clearance and tumor blood volume and the effects of vascular modifiers in an experimental tumor. International journal of radiation oncology, biology, physics, 2005, Mar-15, Volume: 61, Issue:4 Topics: Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Contrast Media; Dextrans; Female; Ferrosoferric Oxide; Hydralazine; Iron; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Oxides; Stilbenes; Vasodilator Agents	2005
Synthesis and evaluation of double bond substituted combretastatins. European journal of medicinal chemistry, 2005, Volume: 40, Issue:6 Topics: Amides; Antineoplastic Agents; Bibenzyls; Cell Cycle; Cell Survival; Epoxy Compounds; Formazans; Humans; Inhibitory Concentration 50; K562 Cells; Magnetic Resonance Spectroscopy; Molecular Structure; Spectrophotometry, Ultraviolet; Stilbenes; Tetrazolium Salts; Tubulin; Tubulin Modulators	2005
Synthesis and biological activity of mustard derivatives of combretastatins. Bioorganic & medicinal chemistry letters, 2005, Aug-01, Volume: 15, Issue:15 Topics: Antineoplastic Agents; Bibenzyls; Humans; Inhibitory Concentration 50; Mustard Plant; Neuroblastoma; Nitrogen; Polymers; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured	2005
Targeting of the antivascular drug combretastatin to irradiated tumors results in tumor growth delay. Pharmaceutical research, 2005, Volume: 22, Issue:7 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Combined Modality Therapy; Drug Delivery Systems; Liposomes; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Stilbenes; Tumor Burden	2005
Cancer: one step at a time. Nature, 2005, Jul-28, Volume: 436, Issue:7050 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Bibenzyls; Doxorubicin; Drug Delivery Systems; Drug Therapy, Combination; Humans; Mice; Nanotechnology; Neoplasms; Neovascularization, Pathologic; Stilbenes; Time Factors	2005
Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system. Nature, 2005, Jul-28, Volume: 436, Issue:7050 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Bibenzyls; Carcinoma, Lewis Lung; Coculture Techniques; Doxorubicin; Drug Delivery Systems; Drug Therapy, Combination; Endothelial Cells; Humans; Melanoma, Experimental; Mice; Nanotechnology; Neoplasms; Neovascularization, Pathologic; Stilbenes; Time Factors; Tissue Distribution	2005
Synthesis and cytotoxicity of epoxide and pyrazole analogs of the combretastatins. Bioorganic & medicinal chemistry, 2005, Nov-01, Volume: 13, Issue:21 Topics: Animals; Bibenzyls; Cell Line; Crystallography, X-Ray; Epoxy Compounds; Mice; Molecular Structure; Pyrazoles; Stilbenes; Structure-Activity Relationship	2005
Retrospective power analysis: when? Radiology, 2005, Volume: 237, Issue:2 Topics: Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Contrast Media; Diffusion Magnetic Resonance Imaging; Gadolinium DTPA; Image Processing, Computer-Assisted; Injections, Intraperitoneal; Male; Rats; Rhabdomyosarcoma; Statistics as Topic; Stilbenes	2005
A new approach to combretastatin D2. Organic & biomolecular chemistry, 2006, Jan-07, Volume: 4, Issue:1 Topics: Antineoplastic Agents; Bibenzyls; Boronic Acids; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Crystallography, X-Ray; Endothelial Cells; Female; Humans; Lactones; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Phenol; Phenyl Ethers; Plants, Medicinal; Stilbenes	2006
Design, synthesis, and biological evaluation of combretastatin nitrogen-containing derivatives as inhibitors of tubulin assembly and vascular disrupting agents. Bioorganic & medicinal chemistry, 2006, May-01, Volume: 14, Issue:9 Topics: Animals; Benzaldehydes; Bibenzyls; Cattle; Cell Proliferation; Drug Design; Isomerism; Mice; Molecular Structure; Neoplasms; Regional Blood Flow; Stilbenes; Structure-Activity Relationship; Tubulin; Xenograft Model Antitumor Assays	2006
Novel combretastatin analogues endowed with antitumor activity. Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11 Topics: Animals; Antineoplastic Agents; Benzofurans; Bibenzyls; Binding, Competitive; Biopolymers; Cell Line, Tumor; Cell Nucleus; Colchicine; Endothelial Cells; Endothelium, Vascular; Female; Humans; Mice; Mice, Nude; Microtubules; Organophosphates; Prodrugs; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Thiophenes; Tubulin; Xenograft Model Antitumor Assays	2006
Synthesis and cytotoxic evaluation of combretafurans, potential scaffolds for dual-action antitumoral agents. Journal of medicinal chemistry, 2006, Aug-24, Volume: 49, Issue:17 Topics: Anisoles; Antineoplastic Agents; Bibenzyls; Cell Death; Cell Line, Tumor; Drug Screening Assays, Antitumor; Furans; Humans; Molecular Structure; Neuroblastoma; Stilbenes; Structure-Activity Relationship; Tubulin	2006
New Agents in Clinical Oncology. 24 November 2006, London, UK. IDrugs : the investigational drugs journal, 2007, Volume: 10, Issue:2 Topics: 3-Iodobenzylguanidine; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bibenzyls; Combined Modality Therapy; Enzyme Inhibitors; Humans; Medical Oncology; Neoplasms; Norepinephrine Plasma Membrane Transport Proteins; Poly(ADP-ribose) Polymerase Inhibitors; Proteomics; Stilbenes; Thioredoxins; Topotecan	2007
Synthesis and biological activity of naphthalene analogues of phenstatins: naphthylphenstatins. Bioorganic & medicinal chemistry letters, 2007, Jun-15, Volume: 17, Issue:12 Topics: Antineoplastic Agents; Bibenzyls; HeLa Cells; Humans; Inhibitory Concentration 50; Models, Chemical; Naphthalenes; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured	2007
Retinoblastoma tumor vessel maturation impacts efficacy of vessel targeting in the LH(BETA)T(AG) mouse model. Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:6 Topics: Actins; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Biomarkers, Tumor; Cell Proliferation; Disease Models, Animal; Endoglin; Endothelium, Vascular; Intracellular Signaling Peptides and Proteins; Ki-67 Antigen; Mice; Mice, Transgenic; Microscopy, Fluorescence; Neovascularization, Pathologic; Pericytes; Pregnadienediols; Retinal Neoplasms; Retinoblastoma; Stilbenes	2007
Synthesis and conformational analysis of macrocyclic dihydroxystilbenes linked between the para-para positions. Chemistry (Weinheim an der Bergstrasse, Germany), 2007, Volume: 13, Issue:25 Topics: Antineoplastic Agents; Bibenzyls; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Stereoisomerism; Stilbenes; Structure-Activity Relationship	2007
Combretastatin-chalcone hybrids: synthesis and cytotoxicity. Medicinal chemistry (Shariqah (United Arab Emirates)), 2007, Volume: 3, Issue:4 Topics: Bibenzyls; Cell Line; Cell Survival; Chalcone; Humans; Molecular Structure; Neoplasms; Stilbenes; Structure-Activity Relationship	2007
Conformationally restricted macrocyclic analogues of combretastatins. Bioorganic & medicinal chemistry letters, 2007, Nov-15, Volume: 17, Issue:22 Topics: Bibenzyls; Macrocyclic Compounds; Models, Molecular; Molecular Conformation; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators	2007
Enhanced fluorescence detection of cis-combretastatins by post-column photolysis. Journal of chromatography. A, 2008, Feb-15, Volume: 1181, Issue:1-2 Topics: Bibenzyls; Chromatography, High Pressure Liquid; Photolysis; Spectrometry, Fluorescence; Stilbenes	2008
Combretastatin dinitrogen-substituted stilbene analogues as tubulin-binding and vascular-disrupting agents. Journal of natural products, 2008, Volume: 71, Issue:3 Topics: Animals; Antineoplastic Agents; Bibenzyls; Disease Models, Animal; Drug Design; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Leukemia P388; Mice; Molecular Structure; Neoplasms; Regional Blood Flow; Stilbenes; Tubulin	2008
Synthesis and biological activity of fluorinated combretastatin analogues. Journal of medicinal chemistry, 2008, May-08, Volume: 51, Issue:9 Topics: Animals; Antineoplastic Agents; Bibenzyls; Biopolymers; Cattle; Cell Line, Tumor; Cells, Cultured; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Endothelial Cells; Fluorine; Humans; Microcirculation; Microtubules; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tubulin	2008
Preclinical evaluation of vascular-disrupting agents in Ewing's sarcoma family of tumours. European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:4 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bibenzyls; Bone Neoplasms; Cell Proliferation; Diphosphates; Disease Models, Animal; Doxorubicin; Drug Evaluation, Preclinical; Mice; Mice, Nude; Necrosis; Neoplasm Transplantation; Neovascularization, Pathologic; Sarcoma, Ewing; Stilbenes	2009
E-Combretastatin and E-resveratrol structural modifications: antimicrobial and cancer cell growth inhibitory beta-E-nitrostyrenes. Bioorganic & medicinal chemistry, 2009, Sep-15, Volume: 17, Issue:18 Topics: Anti-Infective Agents; Antineoplastic Agents; Bacteria; Bibenzyls; Cell Line, Tumor; Cell Proliferation; Fungi; Humans; Molecular Structure; Resveratrol; Stilbenes; Structure-Activity Relationship; Styrenes; Tubulin; Tubulin Modulators	2009
Antineoplastic agents. 579. Synthesis and cancer cell growth evaluation of E-stilstatin 3: a resveratrol structural modification. Journal of natural products, 2009, Volume: 72, Issue:9 Topics: Antineoplastic Agents; Bibenzyls; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Molecular Conformation; Molecular Structure; Prodrugs; Resveratrol; Stereoisomerism; Stilbenes; Structure-Activity Relationship	2009
An efficient synthetic strategy for obtaining 4-methoxy carbon isotope labeled combretastatin A-4 phosphate and other Z-combretastatins. Journal of natural products, 2010, Mar-26, Volume: 73, Issue:3 Topics: Bibenzyls; Isotope Labeling; Molecular Structure; Positron-Emission Tomography; Stereoisomerism; Stilbenes	2010
Highly chemo- and stereoselective palladium-catalyzed transfer semihydrogenation of internal alkynes affording cis-alkenes. The Journal of organic chemistry, 2010, May-07, Volume: 75, Issue:9 Topics: Alkenes; Alkynes; Bibenzyls; Catalysis; Dimethylformamide; Hydrogen; Hydrogenation; Hydroxides; Molecular Structure; Palladium; Potassium Compounds; Stereoisomerism; Stilbenes	2010
A novel class of trans-methylpyrazoline analogs of combretastatins: synthesis and in-vitro biological testing. European journal of medicinal chemistry, 2011, Volume: 46, Issue:7 Topics: Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Leukemia L1210; Melanoma, Experimental; Mice; Microtubules; Molecular Docking Simulation; Pyrazoles; Stilbenes; Structure-Activity Relationship; Tubulin Modulators	2011
Design, synthesis, and cytotoxicity of novel 3-arylidenones derived from alicyclic ketones. Chemical biology & drug design, 2011, Volume: 78, Issue:4 Topics: Animals; Antineoplastic Agents; Bibenzyls; Cell Line, Tumor; Cell Survival; Chalcones; Drug Design; Humans; Ketones; Mice; Models, Molecular; Neoplasms; Stilbenes; Structure-Activity Relationship; Tubulin Modulators	2011
Fluorescence lifetime imaging of E-combretastatin uptake and distribution in live mammalian cells. European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:12 Topics: Animals; Bibenzyls; CHO Cells; Cricetinae; HeLa Cells; Humans; Microscopy, Fluorescence, Multiphoton; Stilbenes	2012
Synthesis of a 2-aryl-3-aroyl indole salt (OXi8007) resembling combretastatin A-4 with application as a vascular disrupting agent. Journal of natural products, 2013, Sep-27, Volume: 76, Issue:9 Topics: Animals; Antineoplastic Agents; Bibenzyls; Colchicine; Drug Screening Assays, Antitumor; Humans; Indoles; Inhibitory Concentration 50; Male; Mice; Molecular Structure; Organophosphates; Prodrugs; Prostatic Neoplasms; Stilbenes; Structure-Activity Relationship; Tubulin	2013
In vivo assessment of the vascular disrupting effect of M410 by DCE-MRI biomarker in a rabbit model of liver tumor. Oncology reports, 2014, Volume: 32, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Bibenzyls; Biomarkers, Tumor; Cell Line, Tumor; Liver Neoplasms, Experimental; Magnetic Resonance Imaging; Male; Organophosphates; Rabbits; Stilbenes	2014
Synthesis and cytotoxic activity of a new group of heterocyclic analogues of the combretastatins. Molecules (Basel, Switzerland), 2014, Jun-11, Volume: 19, Issue:6 Topics: Antineoplastic Agents, Phytogenic; Bibenzyls; Cell Line, Tumor; Coumarins; Drug Screening Assays, Antitumor; Ficusin; Furocoumarins; Humans; Molecular Structure; Neoplasms; Stilbenes; Structure-Activity Relationship; Tubulin Modulators	2014
p,p-Dihydroxydihydrostilbenophanes related to antimitotic combretastatins. Conformational analysis and its relationship to tubulin inhibition. The Journal of organic chemistry, 2014, Aug-01, Volume: 79, Issue:15 Topics: Antimitotic Agents; Bibenzyls; Colchicine; Macrocyclic Compounds; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Polymerization; Stilbenes; Tubulin Modulators	2014
Cytotoxicity studies of novel combretastatin and pterostilbene derivatives. BioMed research international, 2014, Volume: 2014 Topics: Bibenzyls; Cell Death; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Resveratrol; Stilbenes	2014
Synthesis and biological evaluation of novel 3,4-diaryl-1,2,5-selenadiazol analogues of combretastatin A-4. European journal of medicinal chemistry, 2014, Nov-24, Volume: 87 Topics: Antineoplastic Agents, Phytogenic; Bibenzyls; Cell Cycle; Cell Proliferation; Drug Screening Assays, Antitumor; Flow Cytometry; Fluorescent Antibody Technique; Heterocyclic Compounds; Humans; Models, Molecular; Molecular Structure; Neoplasms; Selenium; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured	2014
Effects of combretastatin A-4 phosphate on canine normal and tumor tissue-derived endothelial cells. Research in veterinary science, 2017, Volume: 112 Topics: Animals; Bibenzyls; Cells, Cultured; Dogs; Endothelial Cells; Endothelium, Vascular; Humans; Neoplasms; Neovascularization, Pathologic; Phosphates; Stilbenes	2017
Influence of charge transfer on the isomerisation of stilbene derivatives for application in cancer therapy. Physical chemistry chemical physics : PCCP, 2018, Nov-14, Volume: 20, Issue:44 Topics: Antineoplastic Agents; Bibenzyls; Humans; Isomerism; Light; Models, Molecular; Molecular Structure; Neoplasms; Photochemical Processes; Stilbenes; Structure-Activity Relationship; Thermodynamics	2018
Tumors Resistant to Checkpoint Inhibitors Can Become Sensitive after Treatment with Vascular Disrupting Agents. International journal of molecular sciences, 2020, Jul-06, Volume: 21, Issue:13 Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Bibenzyls; CTLA-4 Antigen; Diphosphates; Disease Progression; Drug Resistance, Neoplasm; Female; Immune Checkpoint Inhibitors; Male; Mammary Neoplasms, Animal; Mice; Mice, Inbred C3H; Neovascularization, Pathologic; Stilbenes; Treatment Outcome	2020
Design and synthesis of new trimethoxylphenyl-linked combretastatin analogues loaded on diamond nanoparticles as a panel for ameliorated solubility and antiproliferative activity. Journal of enzyme inhibition and medicinal chemistry, 2022, Volume: 37, Issue:1 Topics: Amides; Antineoplastic Agents; Bibenzyls; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Molecular Structure; Nanoparticles; Solubility; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators	2022