Page last updated: 2024-08-26

combretastatin and fosbretabulin

combretastatin has been researched along with fosbretabulin in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (23.53)29.6817
2010's9 (52.94)24.3611
2020's4 (23.53)2.80

Authors

AuthorsStudies
Hill, SA; Kanthou, C; Parkins, CS; Tozer, GM1
Anthoney, DA; Bibby, MC; Cooper, PA; Kirwan, IG; Lippert, JW; Loadman, PM; Pettit, GR; Shnyder, SD; Swaine, DJ1
Beltrami, L; Busacca, S; Genazzani, AA; Imovilli, D; Massarotti, A; Miglio, G; Pagliai, F; Pirali, T; Sorba, G; Tron, GC; Verotta, L1
Burchill, SA; Dalal, S1
Hogan, F; Minardi, MD; Pettit, GR; Price, PM1
Hua, R; Li, J; Liu, T1
Babu, B; Brockway, O; Dandavati, A; Lee, M; Mooberry, SL; Satam, V; Sjoholm, R; Tzou, S; Westbrook, C; Zeller, M1
Babu, B; Bandi, RK; Behera, AK; Brockway, O; Lee, M; Mishra, BK; Mooberry, SL; Pati, H; Satam, V; Tzou, S; Westbrook, C; Zeller, M1
Bisby, RH; Botchway, SW; Hadfield, JA; McGown, AT; Parker, AW; Scherer, KM1
Chaplin, DJ; Garner, CM; Ghatak, A; Hadimani, MB; Hall, JJ; Hamel, E; Kessler, RJ; Liu, L; Lopez, R; Macdonough, MT; Mason, RP; Nguyen, BL; Pettit, GR; Pinney, KG; Shirali, AR; Sriram, M; Strecker, TE; Trawick, ML1
Lipeeva, AV; Pokrovsky, AG; Pokrovsky, MA; Shakirov, MM; Shults, EE1
Bao, K; Guan, Q; Guo, D; Jiang, M; Liu, C; Wu, Y; Xu, J; Yang, F; Zhang, W1
Aoshima, K; Hoshino, Y; Izumi, Y; Takagi, S1
Kankala, RK; Kankala, S; Nerella, S; Paidakula, S1
Kozhevnikova, AA; Mikhaevich, EI; Salnikova, DI; Scherbakov, A; Shirinian, VZ; Yadykov, AV; Zakharov, AV1
Abourehab, MAS; Beshay, BY; Elbastawesy, MAI; Masoud, RE; Moustafa, AMY; Zakaria, MY; Zaki, I1
Chen, Y; Huang, X; Liu, Z; Wang, H; Zhang, B; Zhang, H; Zhong, W1

Reviews

2 review(s) available for combretastatin and fosbretabulin

ArticleYear
The biology of the combretastatins as tumour vascular targeting agents.
    International journal of experimental pathology, 2002, Volume: 83, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Endothelium, Vascular; Humans; Neoplasms; Neovascularization, Pathologic; Stilbenes

2002
Recent Trends in Tubulin-Binding Combretastatin A-4 Analogs for Anticancer Drug Development.
    Current medicinal chemistry, 2022, Volume: 29, Issue:21

    Topics: Antineoplastic Agents; Bibenzyls; Cell Line, Tumor; Cell Proliferation; Drug Design; Humans; Neoplasms; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2022

Other Studies

15 other study(ies) available for combretastatin and fosbretabulin

ArticleYear
Comparative preclinical pharmacokinetic and metabolic studies of the combretastatin prodrugs combretastatin A4 phosphate and A1 phosphate.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Feb-15, Volume: 10, Issue:4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Area Under Curve; Bibenzyls; Calibration; Cell Line, Tumor; Chromatography; Chromatography, High Pressure Liquid; Coloring Agents; Female; Humans; Inhibitory Concentration 50; Mass Spectrometry; Mice; Models, Chemical; Phosphorylation; Prodrugs; Stilbenes; Tetrazolium Salts; Thiazoles; Time Factors

2004
Synthesis and cytotoxic evaluation of combretafurans, potential scaffolds for dual-action antitumoral agents.
    Journal of medicinal chemistry, 2006, Aug-24, Volume: 49, Issue:17

    Topics: Anisoles; Antineoplastic Agents; Bibenzyls; Cell Death; Cell Line, Tumor; Drug Screening Assays, Antitumor; Furans; Humans; Molecular Structure; Neuroblastoma; Stilbenes; Structure-Activity Relationship; Tubulin

2006
Preclinical evaluation of vascular-disrupting agents in Ewing's sarcoma family of tumours.
    European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bibenzyls; Bone Neoplasms; Cell Proliferation; Diphosphates; Disease Models, Animal; Doxorubicin; Drug Evaluation, Preclinical; Mice; Mice, Nude; Necrosis; Neoplasm Transplantation; Neovascularization, Pathologic; Sarcoma, Ewing; Stilbenes

2009
An efficient synthetic strategy for obtaining 4-methoxy carbon isotope labeled combretastatin A-4 phosphate and other Z-combretastatins.
    Journal of natural products, 2010, Mar-26, Volume: 73, Issue:3

    Topics: Bibenzyls; Isotope Labeling; Molecular Structure; Positron-Emission Tomography; Stereoisomerism; Stilbenes

2010
Highly chemo- and stereoselective palladium-catalyzed transfer semihydrogenation of internal alkynes affording cis-alkenes.
    The Journal of organic chemistry, 2010, May-07, Volume: 75, Issue:9

    Topics: Alkenes; Alkynes; Bibenzyls; Catalysis; Dimethylformamide; Hydrogen; Hydrogenation; Hydroxides; Molecular Structure; Palladium; Potassium Compounds; Stereoisomerism; Stilbenes

2010
A novel class of trans-methylpyrazoline analogs of combretastatins: synthesis and in-vitro biological testing.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Leukemia L1210; Melanoma, Experimental; Mice; Microtubules; Molecular Docking Simulation; Pyrazoles; Stilbenes; Structure-Activity Relationship; Tubulin Modulators

2011
Design, synthesis, and cytotoxicity of novel 3-arylidenones derived from alicyclic ketones.
    Chemical biology & drug design, 2011, Volume: 78, Issue:4

    Topics: Animals; Antineoplastic Agents; Bibenzyls; Cell Line, Tumor; Cell Survival; Chalcones; Drug Design; Humans; Ketones; Mice; Models, Molecular; Neoplasms; Stilbenes; Structure-Activity Relationship; Tubulin Modulators

2011
Fluorescence lifetime imaging of E-combretastatin uptake and distribution in live mammalian cells.
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:12

    Topics: Animals; Bibenzyls; CHO Cells; Cricetinae; HeLa Cells; Humans; Microscopy, Fluorescence, Multiphoton; Stilbenes

2012
Synthesis of a 2-aryl-3-aroyl indole salt (OXi8007) resembling combretastatin A-4 with application as a vascular disrupting agent.
    Journal of natural products, 2013, Sep-27, Volume: 76, Issue:9

    Topics: Animals; Antineoplastic Agents; Bibenzyls; Colchicine; Drug Screening Assays, Antitumor; Humans; Indoles; Inhibitory Concentration 50; Male; Mice; Molecular Structure; Organophosphates; Prodrugs; Prostatic Neoplasms; Stilbenes; Structure-Activity Relationship; Tubulin

2013
Synthesis and cytotoxic activity of a new group of heterocyclic analogues of the combretastatins.
    Molecules (Basel, Switzerland), 2014, Jun-11, Volume: 19, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Bibenzyls; Cell Line, Tumor; Coumarins; Drug Screening Assays, Antitumor; Ficusin; Furocoumarins; Humans; Molecular Structure; Neoplasms; Stilbenes; Structure-Activity Relationship; Tubulin Modulators

2014
Synthesis and biological evaluation of novel 3,4-diaryl-1,2,5-selenadiazol analogues of combretastatin A-4.
    European journal of medicinal chemistry, 2014, Nov-24, Volume: 87

    Topics: Antineoplastic Agents, Phytogenic; Bibenzyls; Cell Cycle; Cell Proliferation; Drug Screening Assays, Antitumor; Flow Cytometry; Fluorescent Antibody Technique; Heterocyclic Compounds; Humans; Models, Molecular; Molecular Structure; Neoplasms; Selenium; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured

2014
Effects of combretastatin A-4 phosphate on canine normal and tumor tissue-derived endothelial cells.
    Research in veterinary science, 2017, Volume: 112

    Topics: Animals; Bibenzyls; Cells, Cultured; Dogs; Endothelial Cells; Endothelium, Vascular; Humans; Neoplasms; Neovascularization, Pathologic; Phosphates; Stilbenes

2017
Photostability and Antiproliferative Activity of Furan Analogues of Combretastatin A-4.
    Chemical research in toxicology, 2022, 11-21, Volume: 35, Issue:11

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Furans; Humans; Molecular Structure; Pharmaceutical Preparations; Quality of Life; Structure-Activity Relationship

2022
Design and synthesis of new trimethoxylphenyl-linked combretastatin analogues loaded on diamond nanoparticles as a panel for ameliorated solubility and antiproliferative activity.
    Journal of enzyme inhibition and medicinal chemistry, 2022, Volume: 37, Issue:1

    Topics: Amides; Antineoplastic Agents; Bibenzyls; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Molecular Structure; Nanoparticles; Solubility; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2022
Novel combretastatin A-4 derivative containing aminophosphonates as dual inhibitors of tubulin and matrix metalloproteinases for lung cancer treatment.
    European journal of medicinal chemistry, 2022, Dec-15, Volume: 244

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Matrix Metalloproteinases; Tubulin; Tubulin Modulators

2022
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