Page last updated: 2024-09-04

combivir and rilpivirine

combivir has been researched along with rilpivirine in 2 studies

Compound Research Comparison

Studies
(combivir)
Trials
(combivir)
Recent Studies (post-2010)
(combivir)
Studies
(rilpivirine)
Trials
(rilpivirine)
Recent Studies (post-2010) (rilpivirine)
122325958093513

Protein Interaction Comparison

ProteinTaxonomycombivir (IC50)rilpivirine (IC50)
Gag-Pol polyproteinHIV-1 M:B_HXB2R0.068
Cytochrome P450 1A2Homo sapiens (human)6.1612
Cytochrome P450 3A4Homo sapiens (human)1.7406
Cytochrome P450 2D6Homo sapiens (human)2.3635
Cytochrome P450 2C9 Homo sapiens (human)0.2818
Cytochrome P450 2C19Homo sapiens (human)0.3363
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.5
Reverse transcriptase/RNaseH Human immunodeficiency virus 10.0759
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.5

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arasteh, K; Boven, K; Crauwels, H; De Wet, J; Gathe, J; Gold, J; Hodder, S; Kumar, P; Mohapi, L; Short, W; Vanveggel, S1
Arribas, J; Deckx, H; Duiculescu, D; Florence, E; Hung, CC; Sension, M; Stevens, M; Tebas, P; Vanveggel, S; Wilkin, T1

Trials

2 trial(s) available for combivir and rilpivirine

ArticleYear
Effect of gender and race on the week 48 findings in treatment-naïve, HIV-1-infected patients enrolled in the randomized, phase III trials ECHO and THRIVE.
    HIV medicine, 2012, Volume: 13, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Black or African American; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Nitriles; Organophosphonates; Pyrimidines; Rilpivirine; Sex Factors; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2012
Lipid levels and changes in body fat distribution in treatment-naive, HIV-1-Infected adults treated with rilpivirine or Efavirenz for 96 weeks in the ECHO and THRIVE trials.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2014, Aug-01, Volume: 59, Issue:3

    Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Aged, 80 and over; Alkynes; Anti-HIV Agents; Benzoxazines; Body Fat Distribution; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir; Young Adult; Zidovudine

2014