colletoic-acid and cyclopropane

colletoic-acid has been researched along with cyclopropane* in 1 studies

Other Studies

1 other study(ies) available for colletoic-acid and cyclopropane

Article	Year
Enantioselective total synthesis of (+)-colletoic acid via catalytic asymmetric intramolecular cyclopropanation of an α-diazo-β-keto diphenylphosphine oxide. Organic letters, 2013, Mar-01, Volume: 15, Issue:5 The enantioselective total synthesis of (+)-colletoic acid, a potent naturally occurring 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor, is described. This total synthesis features a highly enantioselective catalytic asymmetric intramolecular cyclopropanation of an α-diazo-β-keto diphenylphosphine oxide and five highly stereoselective reactions (cyclopropane opening, Diels-Alder reaction, iodolactonization, alkene formation, and reduction of α,β-unsaturated carboxylic acid). Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Aryldialkylphosphatase; Azo Compounds; Carboxylic Acids; Catalysis; Cyclopropanes; Molecular Structure; Sesquiterpenes; Stereoisomerism	2013

Article

Year

Enantioselective total synthesis of (+)-colletoic acid via catalytic asymmetric intramolecular cyclopropanation of an α-diazo-β-keto diphenylphosphine oxide.

Organic letters, 2013, Mar-01, Volume: 15, Issue:5

The enantioselective total synthesis of (+)-colletoic acid, a potent naturally occurring 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor, is described. This total synthesis features a highly enantioselective catalytic asymmetric intramolecular cyclopropanation of an α-diazo-β-keto diphenylphosphine oxide and five highly stereoselective reactions (cyclopropane opening, Diels-Alder reaction, iodolactonization, alkene formation, and reduction of α,β-unsaturated carboxylic acid).

Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Aryldialkylphosphatase; Azo Compounds; Carboxylic Acids; Catalysis; Cyclopropanes; Molecular Structure; Sesquiterpenes; Stereoisomerism

2013