colforsin has been researched along with yohimbine in 70 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (24.29) | 18.7374 |
| 1990's | 42 (60.00) | 18.2507 |
| 2000's | 9 (12.86) | 29.6817 |
| 2010's | 2 (2.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
| Bradley, ME; Buxton, IL; Keef, KD; Zhang, L | 1 |
| Chan, CB; MacPhail, RM | 1 |
| Lin, W; McCook, EC; Seidler, FJ; Slotkin, TA | 1 |
| Coupry, I; Downing, S; Duzic, E; Lanier, SM | 1 |
| Enero, MA; Kazanietz, MG | 1 |
| Newman, ME | 1 |
| McCook, EC; Nemeroff, CB; Seidler, FJ; Slotkin, TA | 1 |
| De Sarro, G; Nisticó, G | 1 |
| Atkinson, BN; Minneman, KP | 1 |
| Mori-Okamoto, J; Namii, Y; Tatsuno, J | 1 |
| Kasper, G; Marquez, CR; Zatz, M | 1 |
| Felder, CC; Kanterman, RY; McCune, SK; Voigt, MM | 1 |
| Bylund, DB; Halenda, SP; Jones, SB | 1 |
| Andersson, RG; Grundström, N; Karlsson, JO; Norberg, T; Svensson, SP | 1 |
| Bucher, B; Illes, P; Pain, L; Stoclet, JC | 1 |
| Carpéné, C; Galitzky, J; Lafontan, M; Langin, D; Larrouy, D | 1 |
| Alari, L; Axelsson, KL; Persson, ML; Post, C; Uhlén, S; Wikberg, JE | 1 |
| Abrahamsen, J; Nedergaard, OA | 1 |
| Breuiller, M; Ferré, F; Leroy, MJ; Litime, MH; Rouot, B | 1 |
| Burton, MD; Johnson, DC; Kazemi, H | 1 |
| Alberts, P; Ogren, VR; Sellström, AI | 1 |
| Shaikh, IM; Skala, JP | 1 |
| Kotecha, N; Neild, TO | 1 |
| Etgen, AM; Petitti, N | 1 |
| García-Sáinz, JA; Gutiérrez-Venegas, G | 1 |
| Lafontan, M; Langin, D; Paris, H; Stillings, MR | 1 |
| Larsen, PR; Raasmaja, A | 1 |
| Hoyer, D; Schoeffter, P | 1 |
| Crooke, ST; Stadel, JM | 1 |
| Bylund, DB; Ray-Prenger, C; Turner, JT | 1 |
| Andersson, RG; Elwing, H; Grundström, N; Karlsson, JO | 2 |
| Uhlén, S; Wikberg, JE | 1 |
| Neubig, RR; Szamraj, O | 1 |
| Howard-Williams, JR; Lee, PY; Podos, SM; Rose, AD; Severin, CH; Siegel, MJ | 1 |
| Ullrich, S; Wollheim, CB | 1 |
| Kendall, DA; Wilson, VG; Wright, IK | 1 |
| Nakashima, M; Vanhoutte, PM | 1 |
| Hara, M; Inoue, M; Irie, T; Mikami, T; Mikami, Y; Minato, A; Omori, K; Uyama, M; Yasukura, T; Zeng, XT | 1 |
| Cooke, HJ; Wood, JD; Zafirov, DH | 1 |
| Bogoyevitch, MA; Fuller, SJ; Sugden, PH | 1 |
| Harling, R; Kendall, DA; Wilson, VG; Wright, IK | 1 |
| Arilla, E; Guijarro, LG; López-Sañudo, S; Prieto, JC; Puebla, L | 1 |
| Flores, NA; Goulielmos, NV; Seghatchian, MJ; Sheridan, DJ | 1 |
| Regunathan, S; Reis, DJ | 1 |
| Adams, GD; Haynes, JM; Pennefather, JN | 1 |
| Akerman, KE; Jansson, CC; Savola, JM | 1 |
| Corey, J; el Tamer, A; Hanin, I; Raikoff, K; Wülfert, E | 1 |
| Lo, SJ; Shih, YL | 1 |
| Clarke, D; Garg, LC | 1 |
| Garg, LC; Mohuczy-Dominiak, D | 1 |
| Bray, GA; Greenway, FL; Heber, D | 1 |
| Ogihara, M | 1 |
| Andersson, RG; Moartensson, LG | 1 |
| Itoh, Y; Kimura, K; Oka, M; Shimidzu, T; Ukai, Y; Yoshikuni, Y | 1 |
| Goldstein, I; Huang, YH; Moreland, RB; Traish, AM | 1 |
| Gerhardt, CC; Gros, J; Issad, T; Strosberg, AD | 1 |
| Bobirnac, I; Gazi, L; Loetscher, E; Parsley, S; Schoeffter, P | 1 |
| Blandizzi, C; Colucci, R; Del Tacca, M; Tognetti, M | 1 |
| Kaloyianni, M; Papaefthimiou, I; Simeonidou, V | 1 |
| Gutierrez, A; Kornfeld, M; Persson, AE; Salomonsson, M | 1 |
| Akerman, KE; Jansson, CC; Kukkonen, JP | 1 |
| Sugimoto, M; Uchida-Oka, N | 1 |
| Guimarães, S; Mota, A | 1 |
| Azad, SC; DeBock, F; Hapfelmeier, G; Kurz, J; Parsons, CG; Rammes, G; Zieglgänsberger, W | 1 |
| Ohta, H; Ozoe, Y; Utsumi, T | 1 |
| Centurión, D; Gupta, S; Mehrotra, S; Saxena, PR; VandenBrink, AM; Villalón, CM | 1 |
| Iida, H; Kozawa, O; Matsushima-Nishiwaki, R; Tanabe, K | 1 |
1 trial(s) available for colforsin and yohimbine
| Article | Year |
|---|---|
Topical fat reduction.
Topics: Adipose Tissue; Aminophylline; Colforsin; Female; Humans; Injections; Isoproterenol; Lipolysis; Ointments; Thigh; Weight Loss; Yohimbine | 1995 |
69 other study(ies) available for colforsin and yohimbine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Action of alpha 2A-adrenergic receptors in circular smooth muscle of canine proximal colon.
Topics: Adenylate Cyclase Toxin; Animals; Binding, Competitive; Cell Membrane; Clonidine; Colforsin; Colon; Dogs; Epinephrine; Female; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Oxymetazoline; Pertussis Toxin; Prazosin; Receptors, Adrenergic, alpha; Tetrodotoxin; Virulence Factors, Bordetella; Yohimbine | 1992 |
Functional characterization of alpha-adrenoceptors on pancreatic islets of fa/fa Zucker rats.
Topics: Animals; Cells, Cultured; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Female; Glucose; Insulin; Islets of Langerhans; Obesity; Prazosin; Rats; Rats, Zucker; Receptors, Adrenergic, alpha; Yohimbine | 1992 |
Overexpression of alpha 2-adrenergic receptors in fetal rat heart: receptors in search of a function.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Clonidine; Colforsin; Fetal Heart; Gestational Age; In Vitro Techniques; Isoproterenol; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Yohimbine | 1992 |
Factors determining the specificity of signal transduction by guanine nucleotide-binding protein-coupled receptors. I. Coupling of alpha 2-adrenergic receptor subtypes to distinct G-proteins.
Topics: 3T3 Cells; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cell Membrane; Colforsin; Cyclic AMP; Epinephrine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Mice; Pertussis Toxin; Quinoxalines; Receptors, Adrenergic, alpha; RNA, Messenger; Signal Transduction; Transfection; Virulence Factors, Bordetella; Yohimbine | 1992 |
Role of cyclic AMP in the release of noradrenaline from isolated rat atria. Effect of pretreatment with clenbuterol.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Clenbuterol; Colforsin; Cyclic AMP; Electric Stimulation; Heart; In Vitro Techniques; Myocardium; Norepinephrine; Rats; Rats, Wistar; Yohimbine | 1992 |
Serotonin inhibits adenylate cyclase in human platelet membranes.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Binding Sites; Blood Platelets; Colforsin; Dose-Response Relationship, Drug; Humans; Methysergide; Quinoxalines; Receptors, Serotonin; Serotonin; Spiperone; Yohimbine | 1992 |
Species differences in alpha 2-adrenergic regulation of platelet adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adult; Alprostadil; Animals; Blood Platelets; Clonidine; Colforsin; Down-Regulation; Humans; Male; Rabbits; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Statistics as Topic; Yohimbine | 1991 |
Effects of pertussis toxin, dibutyryl-cyclic-AMP, bromo-cyclic-AMP and forskolin on the behavioural and electrocortical power spectrum changes induced by microinfusion of interleukin-2 into the locus coeruleus.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylate Cyclase Toxin; Animals; Antibodies, Monoclonal; Behavior, Animal; Bucladesine; Colforsin; Dose-Response Relationship, Drug; Electroencephalography; Humans; Interleukin-2; Locus Coeruleus; Male; Microinjections; Naloxone; Pertussis Toxin; Rats; Rats, Inbred Strains; Recombinant Proteins; Virulence Factors, Bordetella; Yohimbine | 1991 |
Multiple adrenergic receptor subtypes controlling cyclic AMP formation: comparison of brain slices and primary neuronal and glial cultures.
Topics: Adrenergic alpha-Agonists; Aging; Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Drug Synergism; Isoproterenol; Kinetics; Neuroglia; Neurons; Norepinephrine; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1991 |
Subtypes of adrenergic receptors and intracellular mechanisms involved in modulatory effects of noradrenaline on glutamate.
Topics: Acebutolol; Albuterol; Animals; Cells, Cultured; Cerebellum; Chick Embryo; Clonidine; Colforsin; Electric Conductivity; Ethanolamines; Glutamates; Glutamic Acid; Isoproterenol; Membrane Potentials; Neurons; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tolazoline; Yohimbine | 1991 |
Vasoactive intestinal peptide stimulates chick pineal melatonin production and interacts with other stimulatory and inhibitory agents but does not show alpha 1-adrenergic potentiation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Chickens; Colforsin; Drug Interactions; Isoproterenol; Kinetics; Light; Melatonin; Nitrendipine; Norepinephrine; Phenylephrine; Pineal Gland; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1990 |
The rat alpha 2-C4 adrenergic receptor gene encodes a novel pharmacological subtype.
Topics: Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Blotting, Northern; Colforsin; Cyclic AMP; Dioxanes; DNA; Gene Expression; Humans; Molecular Sequence Data; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; RNA; Sequence Homology, Nucleic Acid; Transfection; Yohimbine | 1991 |
Alpha 2-adrenergic receptor stimulation of phospholipase A2 and of adenylate cyclase in transfected Chinese hamster ovary cells is mediated by different mechanisms.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Enzyme Activation; Female; Kinetics; Membranes; Ovary; Pertussis Toxin; Phospholipases A; Phospholipases A2; Prazosin; Quinacrine; Receptors, Adrenergic, alpha; Signal Transduction; Stimulation, Chemical; Time Factors; Transfection; Tritium; Virulence Factors, Bordetella; Yohimbine | 1991 |
MCH-induced pigment aggregation in teleost melanophores is associated with a cAMP reduction.
Topics: Animals; Colforsin; Cyclic AMP; Fishes; Hypothalamic Hormones; Intracellular Fluid; Melanins; Melanophores; Pigments, Biological; Pituitary Hormones; Signal Transduction; Yohimbine | 1991 |
Role of cyclic AMP in the prejunctional alpha 2-adrenoceptor modulation of noradrenaline release from the rat tail artery.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arteries; Axons; Azepines; Colforsin; Cyclic AMP; Electric Stimulation; Male; Nerve Endings; Neuromuscular Junction; Norepinephrine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Rolipram; Tail; Time Factors; Tritium; Vasoconstriction; Yohimbine | 1990 |
Non-adrenergic sites for imidazolines are not directly involved in the alpha 2-adrenergic antilipolytic effect of UK 14304 in rat adipocytes.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Brimonidine Tartrate; Bucladesine; Cell Membrane; Colforsin; Dioxanes; Idazoxan; Kinetics; Lipolysis; Phentolamine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
Antinociceptive actions of alpha 2-adrenoceptor agonists in the rat spinal cord: evidence for antinociceptive alpha 2-adrenoceptor subtypes and dissociation of antinociceptive alpha 2-adrenoceptors from cyclic AMP.
Topics: Adrenergic alpha-Agonists; Animals; Benzylamines; Brimonidine Tartrate; Colforsin; Cyclic AMP; Guanfacine; Male; Neurotoxins; Nociceptors; Pain Measurement; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Spinal Cord; Yohimbine | 1990 |
Lack of presynaptic modulation by isoprenaline of 3H-noradrenaline release from rabbit isolated ear artery.
Topics: Animals; Arteries; Autonomic Fibers, Postganglionic; Colforsin; Ear, External; Electric Stimulation; Female; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Phentolamine; Phosphodiesterase Inhibitors; Propranolol; Pyrimidines; Rabbits; Tritium; Yohimbine | 1991 |
Functional coupling of the alpha 2-adrenergic receptor-adenylate cyclase complex in the pregnant human myometrium.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adult; Binding, Competitive; Clonidine; Colforsin; Cyclic AMP; Dioxanes; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Female; GTP-Binding Proteins; Humans; Idazoxan; Myometrium; Norepinephrine; Pertussis Toxin; Pregnancy; Pregnancy Trimester, Third; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella; Yohimbine | 1990 |
Adrenergic and cholinergic interaction in central ventilatory control.
Topics: Acetylcholine; Animals; Atropine; Cardiovascular Physiological Phenomena; Cardiovascular System; Clonidine; Colforsin; Cyclic AMP; Dogs; Isoproterenol; Medulla Oblongata; Propanolamines; Receptors, Adrenergic; Receptors, Cholinergic; Respiration; Respiratory Center; Second Messenger Systems; Yohimbine | 1990 |
Role of adenosine 3',5'-cyclic monophosphate in adrenoceptor-mediated control of 3H-noradrenaline secretion in guinea-pig ileum myenteric nerve terminals.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Ileum; In Vitro Techniques; Isoproterenol; Male; Myenteric Plexus; Nerve Endings; Nicotinic Acids; Norepinephrine; Phosphodiesterase Inhibitors; Propranolol; Receptors, Adrenergic; Yohimbine | 1985 |
Alpha 2-adrenergic receptors in brown adipose tissue of infant rats--II. Studies on function and regulation.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adipose Tissue, Brown; Animals; Clonidine; Colforsin; Hydroxydopamines; Kinetics; Lipolysis; Oxidopamine; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathectomy, Chemical; Virulence Factors, Bordetella; Yohimbine | 1988 |
A study of the phasic response of arterioles of the guinea pig small intestine to prolonged exposure to norepinephrine.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arterioles; Clonidine; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Intestine, Small; Isoproterenol; Membrane Potentials; Norepinephrine; Oxidation-Reduction; Propranolol; Temperature; Theophylline; Vasoconstriction; Yohimbine | 1989 |
Progesterone depression of norepinephrine-stimulated cAMP accumulation in hypothalamic slices.
Topics: Animals; Colforsin; Cyclic AMP; Estradiol; Female; Hypothalamus; In Vitro Techniques; Norepinephrine; Phosphoric Diester Hydrolases; Prazosin; Preoptic Area; Progesterone; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1989 |
Activation of protein kinase C alters the interaction of alpha 2-adrenoceptors and the inhibitory GTP-binding protein (Gi) in human platelets.
Topics: Binding, Competitive; Blood Platelets; Colforsin; Enzyme Activation; Epinephrine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Protein Kinase C; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Yohimbine | 1989 |
[3H]RX821002: a new tool for the identification of alpha 2A-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Binding, Competitive; Catecholamines; Cell Membrane; Colforsin; Cyclic AMP; Dioxanes; Dioxins; Humans; Idazoxan; Kinetics; Radioligand Assay; Receptors, Adrenergic, alpha; Tumor Cells, Cultured; Yohimbine | 1989 |
Alpha 1- and beta-adrenergic agents cause synergistic stimulation of the iodothyronine deiodinase in rat brown adipocytes.
Topics: Adipose Tissue, Brown; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Alprenolol; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Activation; Imidazoles; Iodide Peroxidase; Isoproterenol; Male; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1989 |
5-Hydroxytryptamine 5-HT1B and 5-HT1D receptors mediating inhibition of adenylate cyclase activity. Pharmacological comparison with special reference to the effects of yohimbine, rauwolscine and some beta-adrenoceptor antagonists.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Cattle; Colforsin; In Vitro Techniques; Kinetics; Male; Rats; Receptors, Serotonin; Substantia Nigra; Yohimbine | 1989 |
Differential effects of fluoride on adenylate cyclase activity and guanine nucleotide regulation of agonist high-affinity receptor binding.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Anura; Cell Membrane; Cells, Cultured; Colforsin; Dihydroalprenolol; Epinephrine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Iodocyanopindolol; Isoproterenol; Pindolol; Receptors, Adrenergic, beta; Sodium Fluoride; Yohimbine | 1988 |
Alpha 2-adrenergic receptors in the human cell line, HT29. Characterization with the full agonist radioligand [3H]UK-14,304 and inhibition of adenylate cyclase.
Topics: Adenocarcinoma; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Brimonidine Tartrate; Cell Line; Clonidine; Colforsin; Colonic Neoplasms; Dose-Response Relationship, Drug; Guanosine Triphosphate; Humans; Kinetics; Magnesium; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1985 |
Comparative studies on nerve- and noradrenaline-induced melanosome aggregation within different species of fish.
Topics: Adrenergic alpha-Antagonists; Animals; Colforsin; Electric Stimulation; Fishes; Melanocytes; Neurons; Norepinephrine; Potassium; Species Specificity; Yohimbine | 1987 |
Inhibition of cyclic AMP production by alpha 2-adrenoceptor stimulation in the guinea-pig spinal cord slices.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Brimonidine Tartrate; Colforsin; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Male; Prazosin; Quinoxalines; Spinal Cord; Yohimbine | 1988 |
Pigment migration in fish erythrophores is controlled by alpha 2-adrenoceptors.
Topics: Animals; Chromatophores; Colforsin; Electric Stimulation; Fishes; Norepinephrine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Large-scale purification of alpha 2-adrenergic receptor-enriched membranes from human platelets. Persistent association of guanine nucleotides with nonpurified membranes.
Topics: Adenylyl Cyclases; Blood Platelets; Cell Fractionation; Cell Membrane; Centrifugation, Density Gradient; Clonidine; Colforsin; Epinephrine; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Norepinephrine; Receptors, Adrenergic, beta; Tritium; Yohimbine | 1986 |
Pharmacological testing in the laser-induced monkey glaucoma model.
Topics: Administration, Topical; Animals; Colforsin; Dinoprost; Diterpenes; Epinephrine; Glaucoma; Intraocular Pressure; Lasers; Macaca fascicularis; Pilocarpine; Prostaglandins F; Radiation Injuries, Experimental; Sodium Chloride; Timolol; Vanadates; Vanadium; Yohimbine | 1985 |
Islet cyclic AMP levels are not lowered during alpha 2-adrenergic inhibition of insulin release.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antihypertensive Agents; Clonidine; Colforsin; Cyclic AMP; Diterpenes; Epinephrine; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Yohimbine | 1984 |
Alpha 2-adrenoceptor mediated inhibition of forskolin-stimulated cyclic AMP accumulation in isolated porcine palmar lateral veins.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Colforsin; Cyclic AMP; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Pyrrolidinones; Receptors, Adrenergic, alpha-2; Rolipram; Swine; Veins; Yohimbine | 1995 |
Isoproterenol causes hyperpolarization through opening of ATP-sensitive potassium channels in vascular smooth muscle of the canine saphenous vein.
Topics: Animals; Atenolol; Charybdotoxin; Colforsin; Dogs; Female; Glyburide; Ion Channel Gating; Isoproterenol; Male; Membrane Potentials; Muscle, Smooth, Vascular; Ouabain; Potassium Channels; Propanolamines; Receptors, Adrenergic, beta; Saphenous Vein; Scorpion Venoms; Yohimbine | 1995 |
Adrenergic receptor-mediated Cl- transport in rabbit corneal endothelial cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetates; Acetazolamide; Adrenergic Agonists; Adrenergic Antagonists; Affinity Labels; Animals; Brimonidine Tartrate; Cells, Cultured; Chlorides; Colforsin; Dose-Response Relationship, Drug; Endothelium, Corneal; Fluorescent Dyes; Ion Transport; Isoproterenol; Microscopy, Fluorescence; Norepinephrine; Phentolamine; Phenylephrine; Photometry; Quinolines; Quinoxalines; Rabbits; Receptors, Adrenergic; Yohimbine | 1995 |
Elevation of cAMP facilitates noradrenergic transmission in submucous neurons of guinea pig ileum.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Antagonists; Animals; Colforsin; Cyclic AMP; Dioxanes; Electric Stimulation; Ganglia; Guinea Pigs; Idazoxan; Ileum; Membrane Potentials; Microelectrodes; Neurons; Norepinephrine; Phentolamine; Receptors, Purinergic; Synaptic Transmission; Yohimbine | 1993 |
cAMP and protein synthesis in isolated adult rat heart preparations.
Topics: 1-Methyl-3-isobutylxanthine; Adenine Nucleotides; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Energy Metabolism; Epinephrine; Glucagon; Heart; Hypertension; In Vitro Techniques; Isoproterenol; Kinetics; Male; Myocardium; Perfusion; Phenylephrine; Phosphocreatine; Prazosin; Propranolol; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Yohimbine | 1993 |
Examination of the role of inhibition of cyclic AMP in alpha 2-adrenoceptor mediated contractions of the porcine isolated palmar lateral vein.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Forelimb; Norepinephrine; Prazosin; Veins; Yohimbine | 1995 |
Alpha-2 adrenoceptors modulate the somatostatinergic system and G protein levels in the rat hippocampus.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Clonidine; Colforsin; GTP-Binding Proteins; Hippocampus; Kinetics; Male; Membranes; Pertussis Toxin; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Somatostatin; Virulence Factors, Bordetella; Yohimbine | 1995 |
Myocardial ischaemia induces platelet activation with adverse electrophysiological and arrhythmogenic effects.
Topics: Animals; Arrhythmias, Cardiac; Aspirin; Biphenyl Compounds; Blood Platelets; Colforsin; Diterpenes; Electrophysiology; Ginkgolides; Guinea Pigs; Heart; Heptanoic Acids; Lactones; Male; Myocardial Ischemia; Oxidopamine; Platelet Activating Factor; Platelet Activation; Platelet Aggregation Inhibitors; Receptors, Thromboxane; Yohimbine | 1994 |
Effects of moxonidine, an imidazoline antihypertensive agent, on second messenger systems in rat brain.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Antihypertensive Agents; Brain Chemistry; Brain Stem; Brimonidine Tartrate; Cerebral Cortex; Colforsin; Cyclic AMP; Cyclic GMP; Imidazoles; In Vitro Techniques; Norepinephrine; Phosphatidylinositols; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Second Messenger Systems; Yohimbine | 1994 |
Alpha 2-adrenoceptors in the guinea-pig uterus: heterogeneity in the circular and longitudinal smooth muscle layers.
Topics: Adrenergic alpha-Agonists; Animals; Binding, Competitive; Colforsin; Cyclic AMP; Female; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Muscle, Smooth; Myometrium; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Uterine Contraction; Uterus; Yohimbine | 1993 |
Different sensitivity of alpha 2A-C10 and alpha 2C-C4 receptor subtypes in coupling to inhibition of cAMP accumulation.
Topics: Adenine; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Clonidine; Colforsin; Cyclic AMP; Fibroblasts; Humans; Imidazoles; Kinetics; Medetomidine; Norepinephrine; Receptors, Adrenergic, alpha-2; Tetradecanoylphorbol Acetate; Transfection; Yohimbine | 1994 |
ucb 11056, a new potential nootropic drug, amplifies induced cyclic AMP formation in rat brain tissue.
Topics: Analysis of Variance; Animals; Brain; Colforsin; Cyclic AMP; Hippocampus; In Vitro Techniques; Isoproterenol; Kinetics; Male; Morpholines; Propranolol; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Time Factors; Triazines; Yohimbine | 1993 |
Induction of cell expansion of goldfish melanocytoma cells (GMM-1) by epinephrine and dexamethasone requires external calcium.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cell Line; Cell Size; Clonidine; Colforsin; Dexamethasone; Diglycerides; Egtazic Acid; Epinephrine; Goldfish; Melanoma; Nifedipine; Receptors, Adrenergic; Tumor Cells, Cultured; Yohimbine | 1993 |
Alpha-2 adrenergic receptors in inner medullary collecting duct cells of the rabbit kidney.
Topics: Animals; Arginine Vasopressin; Colforsin; Cyclic AMP; In Vitro Techniques; Kidney Medulla; Kidney Tubules, Collecting; Male; Osmolar Concentration; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1993 |
Alpha-2 adrenoceptors in medullary thick ascending limbs of the rabbit kidney.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Arginine Vasopressin; Binding, Competitive; Colforsin; Cyclic AMP; In Vitro Techniques; Kidney Medulla; Kinetics; Male; Rabbits; Radioligand Assay; Receptors, Adrenergic, alpha; Stimulation, Chemical; Tritium; Yohimbine | 1993 |
Cell-density-dependent expression of the alpha(2)-adrenergic response by epidermal growth factor (EGF) in primary cultures of adult rat hepatocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cell Count; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Cytochalasin B; Epidermal Growth Factor; Genistein; Isoflavones; Liver; Male; Oxymetazoline; Pertussis Toxin; Protein Biosynthesis; Proteins; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella; Yohimbine | 1996 |
Denervation of pigment cells lead to a receptor that is ultrasensitive to melatonin and noradrenaline.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Colforsin; Denervation; Fishes; Melanins; Melanophores; Melatonin; Norepinephrine; Peripheral Nervous System; Prazosin; Yohimbine | 1997 |
Involvement of metabotropic glutamate receptors in Gi- and Gs-dependent modulation of adenylate cyclase activity induced by a novel cognition enhancer NS-105 in rat brain.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Alanine; Animals; Baclofen; Brimonidine Tartrate; Cell Membrane; Cerebral Cortex; Cholera Toxin; Cognition; Colforsin; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isoproterenol; Kinetics; Male; Manganese; Pertussis Toxin; Piperidines; Proline; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Neurotransmitter; Virulence Factors, Bordetella; Yohimbine | 1997 |
Expression of functional alpha2-adrenergic receptor subtypes in human corpus cavernosum and in cultured trabecular smooth muscle cells.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Binding, Competitive; Brimonidine Tartrate; Cells, Cultured; Colforsin; Cyclic AMP; Humans; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Penis; Quinoxalines; Radioisotopes; Receptors, Adrenergic, alpha-2; Ribonucleases; RNA, Messenger; Yohimbine | 1997 |
Stimulation of the extracellular signal-regulated kinase 1/2 pathway by human beta-3 adrenergic receptor: new pharmacological profile and mechanism of activation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Bupranolol; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Colforsin; Cricetinae; Dioxoles; Enzyme Activation; Epinephrine; Ethanolamines; Humans; Insulin; Isoproterenol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Norepinephrine; Phentolamine; Prazosin; Propanolamines; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Signal Transduction; Yohimbine | 1999 |
Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guanfacine; Humans; Idazoxan; Isoquinolines; Neuroblastoma; Oxymetazoline; Piperazines; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Yohimbine | 1999 |
Histamine H(3) receptors mediate inhibition of noradrenaline release from intestinal sympathetic nerves.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Adrenergic alpha-Antagonists; Animals; Calcium; Colforsin; Dose-Response Relationship, Drug; Ethylmaleimide; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Ileum; In Vitro Techniques; Intestinal Mucosa; Intestines; Male; Muscle, Smooth; Myenteric Plexus; Nifedipine; Norepinephrine; omega-Conotoxins; Pertussis Toxin; Phenols; Receptors, Histamine H3; Rolipram; Sympathetic Nervous System; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetrodotoxin; Virulence Factors, Bordetella; Yohimbine | 2000 |
Metabolic effects induced by epinephrine in Rana balcanica erythrocytes under normoxic and hypoxic conditions.
Topics: Adenosine Triphosphate; Adrenergic Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Colforsin; Cyclic AMP; Epinephrine; Erythrocytes; Glucose; Hypoxia; Lactic Acid; Ouabain; Oxygen; Perchlorates; Phosphofructokinase-1; Prazosin; Propranolol; Pyruvic Acid; Ranidae; Sodium-Potassium-Exchanging ATPase; Time Factors; Yohimbine | 2000 |
The influence of beta-adrenergic activation on noradrenergic alpha1 activation of rabbit afferent arterioles.
Topics: Adenylyl Cyclases; Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Arterioles; Calcium; Colforsin; Cyclic AMP; Cytosol; Enzyme Activation; Fluorescent Dyes; Fura-2; Isoproterenol; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 2000 |
Agonist trafficking of G(i/o)-mediated alpha(2A)-adrenoceptor responses in HEL 92.1.7 cells.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Biological Transport; Calcium; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Idazoxan; Pertussis Toxin; Propranolol; Receptors, Adrenergic, alpha-2; Tumor Cells, Cultured; Virulence Factors, Bordetella; Yohimbine | 2001 |
Norepinephrine induces apoptosis in skin melanophores by attenuating cAMP-PKA signals via alpha2-adrenoceptors in the medaka, Oryzias latipes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Apoptosis; Clonidine; Colforsin; Culture Techniques; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cysteine Proteinase Inhibitors; Isoquinolines; Melanophores; Norepinephrine; Oligopeptides; Oryzias; Phenylephrine; Prazosin; Protein Isoforms; Receptors, Adrenergic, alpha-2; Signal Transduction; Skin; Skin Pigmentation; Sulfonamides; Yohimbine | 2001 |
Interaction between alpha2-autoreceptors and receptors mediating the effects of angiotensin II and bradykinin in the heart of newborn rats.
Topics: Adrenergic alpha-Antagonists; Alkaloids; Angiotensin II; Animals; Animals, Newborn; Autoreceptors; Benzophenanthridines; Bradykinin; Colforsin; Electric Stimulation; In Vitro Techniques; Myocardium; Norepinephrine; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Bradykinin; Staurosporine; Yohimbine | 2002 |
Alpha2-adrenoreceptor activation inhibits LTP and LTD in the basolateral amygdala: involvement of Gi/o-protein-mediated modulation of Ca2+-channels and inwardly rectifying K+-channels in LTD.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Barium; Cadmium; Calcium Channel Blockers; Calcium Channels; Clonidine; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 4; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Heterotrimeric GTP-Binding Proteins; Imines; In Vitro Techniques; Isoquinolines; Long-Term Potentiation; Long-Term Synaptic Depression; Membrane Potentials; Mice; Norepinephrine; omega-Agatoxin IVA; omega-Conotoxins; Patch-Clamp Techniques; Pertussis Toxin; Piperazines; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Pyridines; Receptors, Adrenergic, alpha-2; Serotonin Antagonists; Sulfonamides; Yohimbine | 2003 |
B96Bom encodes a Bombyx mori tyramine receptor negatively coupled to adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Bombyx; Cells, Cultured; Chlorpromazine; Cloning, Molecular; Colforsin; Cyclic AMP; Dopamine; Drug Interactions; Humans; Neurotransmitter Agents; Norepinephrine; Octopamine; Receptors, Biogenic Amine; Tyramine; Yohimbine | 2003 |
A61603-induced contractions of the porcine meningeal artery are mediated by alpha1- and alpha2-adrenoceptors.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Alkaloids; Animals; Benzophenanthridines; Colforsin; Dose-Response Relationship, Drug; Female; Forecasting; Imidazoles; In Vitro Techniques; Meningeal Arteries; Methiothepin; Norepinephrine; Oxadiazoles; Phenylephrine; Piperazines; Potassium Chloride; Prazosin; Protein Kinase C; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Ritanserin; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Swine; Tetrahydronaphthalenes; Vasoconstriction; Yohimbine | 2007 |
Dexmedetomidine suppresses interleukin-1β-induced interleukin-6 synthesis in rat glial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line, Tumor; Colforsin; Dexmedetomidine; Gene Expression Regulation; I-kappa B Kinase; Interleukin-1beta; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Neuroglia; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Receptors, Adrenergic, alpha-2; RNA, Messenger; Tetradecanoylphorbol Acetate; Yohimbine | 2014 |