Compounds > colforsin
Page last updated: 2024-08-23

colforsin and vx-770

colforsin has been researched along with vx-770 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (62.50)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Bolger, GB; Clancy, JP; Ehrhardt, A; Fan, L; Li, Y; Mitchell, LH; Naren, AP; Pyle, LC; Ren, A; Rowe, SM; Sorscher, EJ1
Birket, SE; Chu, KK; Fernandez, CM; Grizzle, WE; Hanes, J; Houser, GH; Lin, V; Liu, L; Mazur, M; Rowe, SM; Shastry, S; Sloane, PA; Solomon, GM; Sorscher, EJ; Tearney, GJ1
Aban, I; Boyles, SE; Chaudhry, IG; Chua, M; Gentzsch, M; Guimbellot, JS; Jaspers, I; Leach, JM; Quinney, NL1
Boyles, SE; Cholon, DM; Gentzsch, M; Martino, MEB; Quinney, NL; Ribeiro, CMP1
Bijvelds, MJC; Bose, SJ; Bot, AGM; Cai, Z; de Jonge, HR; Liu, J; Sheppard, DN; Wang, Y1
Becq, F; Cantereau, A; Froux, L; Llinares, J1
Bertini, M; Conti, J; Farinazzo, A; Kleinfelder, K; Latorre, RV; Lotti, V; Massella, A; Melotti, P; Rodella, L; Somenza, E; Sorio, C; Tomba, F1
Amato, F; Castaldo, G; Hristodor, AM; Kleinfelder, K; Laudanna, C; Melotti, P; Sorio, C; Villella, VR1

Other Studies

8 other study(ies) available for colforsin and vx-770

ArticleYear
Regulatory domain phosphorylation to distinguish the mechanistic basis underlying acute CFTR modulators.
    American journal of physiology. Lung cellular and molecular physiology, 2011, Volume: 301, Issue:4

    Topics: Aminophenols; Animals; Blotting, Western; Cell Line; Chlorocebus aethiops; Colforsin; Cresols; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diffusion Chambers, Culture; Dimerization; Enzyme-Linked Immunosorbent Assay; Gene Expression; High-Throughput Screening Assays; Humans; Ion Channel Gating; Ion Transport; Lentivirus; Membrane Transport Modulators; Mice; Mutation; Phosphorylation; Protein Structure, Tertiary; Pyrazoles; Quinolones; Retroviridae; Transduction, Genetic

2011
Combination therapy with cystic fibrosis transmembrane conductance regulator modulators augment the airway functional microanatomy.
    American journal of physiology. Lung cellular and molecular physiology, 2016, 05-15, Volume: 310, Issue:10

    Topics: Amiloride; Aminophenols; Animals; Cells, Cultured; Chloride Channel Agonists; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Membrane Potentials; Mice; Mutation, Missense; NIH 3T3 Cells; Quinolones

2016
Nasospheroids permit measurements of CFTR-dependent fluid transport.
    JCI insight, 2017, 11-16, Volume: 2, Issue:22

    Topics: Aminophenols; Aminopyridines; Benzodioxoles; Biological Transport; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Combinations; Humans; Mutation; Nasal Mucosa; Particle Size; Precision Medicine; Quinolones; Spheroids, Cellular

2017
The cystic fibrosis airway milieu enhances rescue of F508del in a pre-clinical model.
    The European respiratory journal, 2018, Volume: 52, Issue:6

    Topics: Aminophenols; Aminopyridines; Benzodioxoles; Bronchi; Cell Line; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Humans; Inflammation; Mutation; Quinolones; Respiratory System

2018
Differential thermostability and response to cystic fibrosis transmembrane conductance regulator potentiators of human and mouse F508del-CFTR.
    American journal of physiology. Lung cellular and molecular physiology, 2019, 07-01, Volume: 317, Issue:1

    Topics: Adenosine Triphosphate; Aminophenols; Aminopyridines; Animals; Base Sequence; Benzodioxoles; Chloride Channel Agonists; CHO Cells; Colforsin; Cricetulus; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Gene Expression; Genistein; Ion Transport; Mice; NIH 3T3 Cells; Patch-Clamp Techniques; Protein Stability; Quinolones; Sequence Deletion; Species Specificity; Temperature; Transgenes

2019
Quantitative phase imaging to study transmembrane water fluxes regulated by CFTR and AQP3 in living human airway epithelial CFBE cells and CHO cells.
    PloS one, 2020, Volume: 15, Issue:5

    Topics: Aminophenols; Animals; Aquaporin 3; Biological Transport, Active; Biophysical Phenomena; Bronchi; Cell Line; Chloride Channel Agonists; CHO Cells; Colforsin; Cricetulus; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Humans; Microscopy, Interference; Mutant Proteins; Osmosis; Quinolones; Respiratory Mucosa; RNA, Messenger; Water

2020
CFTR Modulators Rescue the Activity of CFTR in Colonoids Expressing the Complex Allele p.[R74W;V201M;D1270N]/dele22_24.
    International journal of molecular sciences, 2023, Mar-08, Volume: 24, Issue:6

    Topics: Alleles; Benzodioxoles; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Humans; Middle Aged; Mutation

2023
Theratyping of the Rare CFTR Genotype A559T in Rectal Organoids and Nasal Cells Reveals a Relevant Response to Elexacaftor (VX-445) and Tezacaftor (VX-661) Combination.
    International journal of molecular sciences, 2023, Jun-19, Volume: 24, Issue:12

    Topics: Benzodioxoles; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genotype; Humans; Mutation; Organoids

2023