colforsin has been researched along with thiazoles in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (6.98) | 18.7374 |
| 1990's | 9 (20.93) | 18.2507 |
| 2000's | 26 (60.47) | 29.6817 |
| 2010's | 5 (11.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nowak, JZ; Sek, B | 2 |
| Huang, TF; Hung, ML; Ouyang, C; Teng, CM | 1 |
| Nielsen, ST | 1 |
| Shukla, SD | 1 |
| Breton, J; Griswold, DE; Marshall, PJ; Torphy, TJ; Webb, EF; White, JR | 1 |
| Felder, RA; Kaskel, FJ; Kinoshita, S; Ohbu, K | 1 |
| Aktories, K; Jonas, JC; Just, I; Li, G; Rungger-Brändle, E; Wollheim, CB | 1 |
| Becq, F; Chang, XB; Hanrahan, JW; Riordan, JR; Verrier, B | 1 |
| Aratake, H; Endo, T; Hasegawa, Y; Kitaguchi, N; Morikawa, A; Ogawa, K; Sugimoto, E | 1 |
| Aikawa, T; Han, L; Hirose, T; Iwasaki, K; Koyanagi, M; Matsumoto, I; Shimada, T; Yang, H | 1 |
| Bodenburg, Y; Gasic, S; Green, A; Nagamani, M; Urban, RJ | 1 |
| Ailhaud, G; Aubert, J; Belmonte, N; Dani, C; Négrel, R; Saint-Marc, P | 1 |
| Nilsson, H | 1 |
| Chern, Y; Huang, CL; Huang, NK; Lin, YW; Messing, RO | 1 |
| Bruchovsky, N; Sadar, MD; Ueda, T | 1 |
| Clyne, CD; Duong, JH; Gong, C; Murata, Y; Rubin, GL; Simpson, ER; Speed, CJ | 1 |
| Bartesaghi, R; Ciani, E; Contestabile, A; Della Valle, G; Guidi, S; Perini, G | 1 |
| Folli, C; Galietta, LJ; Ma, T; Sonawane, ND; Thiagarajah, JR; Verkman, AS; Yang, H | 1 |
| Belinsky, MG; Chen, ZS; Guo, Y; Hopper-Borge, E; Kotova, E; Kruh, GD; Lee, K | 1 |
| Corsini, GU; Maggio, R; Millan, MJ; Novi, F; Scarselli, M | 1 |
| Baldi, A; Davio, C; Fernández, N; Legnazzi, BL; Monczor, F; Riveiro, ME; Shayo, C | 1 |
| Haggie, PM; Song, Y; Thiagarajah, JR; Verkman, AS | 1 |
| Zhong, N; Zucker, RS | 1 |
| Lin, LF; Rubin, LL; Xu, M | 1 |
| Chen, J; Gao, SY; Kobayashi, N; Li, CY; Matsuda, S; Miyawaki, K; Mominoki, K; Pan, L; Saito, K; Saito, S; Shigemoto, K; Terashita, T | 1 |
| Finkbeiner, WF; Muanprasat, C; Nielson, DW; Pedemonte, N; Salinas, DB; Verkman, AS | 1 |
| Findlay, IA; Li, H; Sheppard, DN | 1 |
| Brussee, J; Göblyös, A; Ijzerman, AP; Mulder-Krieger, T; Pietra, D; Santiago, SN; von Frijtag Drabbe Künzel, J | 1 |
| Levin, MH; Verkman, AS | 1 |
| Al-Wadei, N; Hussein, A; Schuller, HM; Takahashi, T | 1 |
| Becq, F; Norez, C; Robert, R | 1 |
| Caci, E; Du, K; Galietta, LJ; Lukacs, GL; Pedemonte, N; Verkman, AS; Zegarra-Moran, O | 1 |
| Cai, J; Guo, Z; Klueber, KM; Lu, C; Qiu, M; Roisen, FJ; Winstead, WI; Zhang, X | 1 |
| Chatsudthipong, V; Kaewmokul, S; Muanprasat, C | 1 |
| Chen, Y; Cheung, YT; Kong, LD; Kung, HF; Mo, SF; Ng, TB; Qiao, C; Xu, HX | 1 |
| Aglah, C; Gordon, T; Posse de Chaves, EI | 1 |
| Lecoeur, S; Mazallon, M; Prouillac, C; Videmann, B | 1 |
| Bécsi, B; Csortos, C; Czikora, I; Erdodi, F; Gergely, P; Kása, A; Kim, KM; Verin, AD | 1 |
| Banks, P; Blanco Suarez, EM; Cockbill, LM; Hanley, JG; Murk, K | 1 |
| Becq, F; Boinot, C; Ferru-Clément, R; Jollivet Souchet, M | 1 |
| Lee, C; Robinson, M; Willerth, SM | 1 |
| Afford, SC; Attard, J; Bhogal, RH; Boteon, APCS; Boteon, YL; Hubscher, S; Mergental, H; Mirza, DF; Reynolds, G; Wallace, L | 1 |
43 other study(ies) available for colforsin and thiazoles
| Article | Year |
|---|---|
Cyclic AMP generating systems in vertebrate retina: effects of histamine and an established retinal modulator, dopamine.
Topics: Adenylyl Cyclases; Animals; Cerebral Cortex; Chickens; Cimetidine; Colforsin; Cyclic AMP; Dimaprit; Dopamine; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Methylhistamines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Retina; Thiazoles; Thiourea | 1991 |
Triwaglerin: a potent platelet aggregation inducer purified from Trimeresurus wagleri snake venom.
Topics: Animals; Calcium Channel Blockers; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Colforsin; Crotalid Venoms; Electrophoresis, Disc; Esterases; Indomethacin; Kinetics; Nitroprusside; Peptides; Platelet Aggregation; Pyrimidinones; Rabbits; Species Specificity; Tetracaine; Thiazoles | 1989 |
H2-receptor antagonist and gastric acid antisecretory properties of Wy-45,662.
Topics: Animals; Bucladesine; Colforsin; Dogs; Gastric Acid; Gastric Mucosa; Heart; Heart Rate; Histamine H2 Antagonists; Male; Phenoxypropanolamines; Pylorus; Rats; Rats, Inbred Strains; Thiazoles | 1986 |
Platelet activating factor-stimulated formation of inositol triphosphate in platelets and its regulation by various agents including Ca2+, indomethacin, CV-3988, and forskolin.
Topics: Animals; Blood Platelets; Calcium; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Indomethacin; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Models, Biological; Phospholipid Ethers; Platelet Activating Factor; Rabbits; Sugar Phosphates; Thiazoles; Time Factors | 1985 |
Stimulatory effect of histamine on cyclic AMP formation in chick pineal gland.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Analysis of Variance; Animals; Carbon Radioisotopes; Chickens; Colforsin; Cyclic AMP; Dimaprit; Guinea Pigs; Hippocampus; Histamine; Histamine Agonists; In Vitro Techniques; Kinetics; Male; Methylhistamines; Pineal Gland; Ranitidine; Rats; Rats, Wistar; Thiazoles; Tritium | 1994 |
Effect of selective phosphodiesterase type IV inhibitor, rolipram, on fluid and cellular phases of inflammatory response.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Calcimycin; Cells, Cultured; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 4; Ear, External; Eicosanoids; Histamine Release; Humans; Imidazoles; Inflammation; Leukotriene B4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Monocytes; Nadolol; Naproxen; Neutrophils; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyrazoles; Pyrrolidinones; Receptors, Adrenergic, beta; Rolipram; SRS-A; Thiazoles | 1993 |
Dopamine-1 receptors in the proximal convoluted tubule of Dahl rats: defective coupling to adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Benzothiazoles; Blood Pressure; Colforsin; Cyclic AMP; Dopamine Agonists; Female; Fenoldopam; Hypertension; Kidney Tubules, Proximal; Male; Pramipexole; Rats; Rats, Inbred Strains; Receptors, Dopamine D1; Sodium, Dietary; Thiazoles | 1995 |
Effect of disruption of actin filaments by Clostridium botulinum C2 toxin on insulin secretion in HIT-T15 cells and pancreatic islets.
Topics: Actin Cytoskeleton; Actins; Animals; Bombesin; Botulinum Toxins; Calcium; Cell Line; Cell Size; Colforsin; Cytochalasins; Exocytosis; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Microscopy, Fluorescence; Oxidation-Reduction; Rats; Tetrazolium Salts; Thiazoles | 1994 |
cAMP- and Ca2+-independent activation of cystic fibrosis transmembrane conductance regulator channels by phenylimidazothiazole drugs.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Calcimycin; Calcium; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Humans; Imidazoles; Isoquinolines; Kinetics; Levamisole; Membrane Potentials; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Point Mutation; Recombinant Proteins; Sulfonamides; Tetramisole; Thiazoles; Transfection | 1996 |
A new compound (AZ36041) promotes the survival of the neurons and reduces neurotoxicity of Alzheimer's beta-amyloid protein.
Topics: Amyloid beta-Peptides; Animals; Cells, Cultured; Cerebral Cortex; Colforsin; Dizocilpine Maleate; Female; Hippocampus; N-Methylaspartate; Neurons; Neuroprotective Agents; Pregnancy; Rats; Rats, Wistar; Sulfonamides; Thiazoles | 1995 |
Effect of PAF receptor antagonists on adrenocortical secretion induced by ACTH in normal and athymic nude mice.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Bucladesine; Colforsin; Corticosterone; Male; Mice; Mice, Inbred ICR; Mice, Nude; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thiazolidines | 1998 |
Troglitazone inhibits progesterone production in porcine granulosa cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Cells, Cultured; Chromans; Colforsin; Estradiol; Female; Follicle Stimulating Hormone; Granulosa Cells; Progesterone; Steroids; Swine; Thiazoles; Thiazolidinediones; Time Factors; Troglitazone | 1998 |
Prostacyclin IP receptor up-regulates the early expression of C/EBPbeta and C/EBPdelta in preadipose cells.
Topics: 3T3 Cells; Adipocytes; Animals; Carrier Proteins; CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Clone Cells; Colforsin; Cyclic AMP; DNA-Binding Proteins; Epoprostenol; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Kinetics; Mice; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Nuclear Proteins; Receptors, Cytoplasmic and Nuclear; Receptors, Epoprostenol; Receptors, Prostaglandin; RNA, Messenger; Rosiglitazone; Signal Transduction; Stem Cells; Thiazoles; Thiazolidinediones; Transcription Factors; Up-Regulation | 2000 |
Melanosome and erythrosome positioning regulates cAMP-induced movement in chromatophores from spotted triplefin, Grahamina capito.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carotenoids; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Fishes; In Vitro Techniques; Melanosomes; Norepinephrine; Skin Physiological Phenomena; Thiazoles; Thiazolidines | 2000 |
Activation of protein kinase A and atypical protein kinase C by A(2A) adenosine receptors antagonizes apoptosis due to serum deprivation in PC12 cells.
Topics: Adenosine; Animals; Apoptosis; Blotting, Western; Cell Membrane; Cell Nucleus; Cell Survival; Chromones; Colforsin; Coloring Agents; Culture Media, Serum-Free; Cyclic AMP-Dependent Protein Kinases; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Genes, Dominant; MAP Kinase Signaling System; Models, Biological; Morpholines; PC12 Cells; Phenethylamines; Phosphoinositide-3 Kinase Inhibitors; Phosphoprotein Phosphatases; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2001 |
Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways.
Topics: Amino Acids; Anilides; Blotting, Northern; Colforsin; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Immunoblotting; Interleukin-6; Janus Kinase 1; Luciferases; Male; MAP Kinase Signaling System; Models, Biological; Nitriles; Phosphorylation; Plasmids; Precipitin Tests; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Tosyl Compounds; Trans-Activators; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2002 |
Ligands for the peroxisomal proliferator-activated receptor gamma and the retinoid X receptor inhibit aromatase cytochrome P450 (CYP19) expression mediated by promoter II in human breast adipose.
Topics: Adipose Tissue; Aromatase; Base Sequence; Chromans; Colforsin; Female; Gene Expression Regulation, Enzymologic; Humans; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Tetradecanoylphorbol Acetate; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2002 |
Nitric oxide protects neuroblastoma cells from apoptosis induced by serum deprivation through cAMP-response element-binding protein (CREB) activation.
Topics: Apoptosis; Blotting, Western; Cell Survival; Colforsin; Culture Media, Serum-Free; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Genes, Reporter; Humans; In Situ Nick-End Labeling; Luciferases; Microscopy, Fluorescence; Mutation; Neuroblastoma; Neurons; Nitric Oxide; Nitrites; Phosphorylation; Plasmids; Protein Isoforms; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2002 |
Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion.
Topics: Amino Acid Substitution; Animals; Cell Membrane; Cholera Toxin; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Diarrhea; Humans; Ileum; Mice; Muscle, Smooth; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Rats; Rats, Inbred F344; Recombinant Proteins; Thiazoles | 2002 |
MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine.
Topics: Adenine; Adenosine Triphosphate; Animals; Antineoplastic Agents; Antiviral Agents; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Cell Membrane; Colforsin; Coloring Agents; Cyclic AMP; Cyclic GMP; DNA, Complementary; Dose-Response Relationship, Drug; Drug Resistance; Floxuridine; Fluorouracil; Genetic Vectors; Growth Inhibitors; Immunoblotting; Inhibitory Concentration 50; Insecta; Models, Biological; Nitrosamines; Nucleotides; Organophosphonates; Swine; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Zalcitabine | 2003 |
Potent activation of dopamine D3/D2 heterodimers by the antiparkinsonian agents, S32504, pramipexole and ropinirole.
Topics: Adenylyl Cyclases; Animals; Antiparkinson Agents; Benzothiazoles; Binding, Competitive; Colforsin; COS Cells; Dimerization; Enzyme Activation; Humans; Indoles; Ligands; Nucleus Accumbens; Oxazines; Pertussis Toxin; Pramipexole; Protein Binding; Receptors, Dopamine D2; Receptors, Dopamine D3; Thiazoles; Transfection | 2003 |
The time-course of cyclic AMP signaling is critical for leukemia U-937 cell differentiation.
Topics: Calcium; Cell Differentiation; Cell Division; Colforsin; Complement C5a; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Humans; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Receptors, Histamine H2; Receptors, Prostaglandin E; Recombinant Proteins; Signal Transduction; Thiazoles; Time Factors; U937 Cells | 2004 |
A small molecule CFTR inhibitor produces cystic fibrosis-like submucosal gland fluid secretions in normal airways.
Topics: Animals; Benzoates; Body Fluids; Bronchi; Cells, Cultured; Chlorides; Cholinergic Agents; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exocrine Glands; Humans; Hydrogen-Ion Concentration; Pilocarpine; Second Messenger Systems; Sodium; Swine; Thapsigargin; Thiazoles; Thiazolidines; Viscosity | 2004 |
Roles of Ca2+, hyperpolarization and cyclic nucleotide-activated channel activation, and actin in temporal synaptic tagging.
Topics: Actins; Animals; Astacoidea; Benzazepines; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Cytochalasin D; Electric Stimulation; In Vitro Techniques; Ion Channels; Long-Term Potentiation; Membrane Potentials; Motor Neurons; Neuromuscular Junction; Pyrimidines; Thiazoles; Thiazolidines; Time Factors | 2004 |
A non-peptidyl neurotrophic small molecule for midbrain dopaminergic neurons.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Astrocytes; Cell Count; Cell Survival; Cells, Cultured; Colforsin; Dopamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glial Cell Line-Derived Neurotrophic Factor; Mesencephalon; Nerve Growth Factors; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Sensitivity and Specificity; Serotonin; Sulfonamides; Thiazoles; Tyrosine 3-Monooxygenase | 2004 |
Rho-ROCK signal pathway regulates microtubule-based process formation of cultured podocytes--inhibition of ROCK promoted process elongation.
Topics: Acetylation; Actin Cytoskeleton; Actins; Acute-Phase Proteins; ADP Ribose Transferases; Amides; Animals; Botulinum Toxins; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Colforsin; Cytoskeleton; Focal Adhesions; Intracellular Signaling Peptides and Proteins; Kidney Glomerulus; Mice; Microtubules; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Signal Transduction; Thiazoles; Thiazolidines; Tubulin | 2004 |
CFTR involvement in nasal potential differences in mice and pigs studied using a thiazolidinone CFTR inhibitor.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Benzoates; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Diuretics; Female; Glyburide; Hypoglycemic Agents; Male; Membrane Potentials; Mice; Mice, Inbred CFTR; Nasal Mucosa; Sus scrofa; Thiazoles; Thiazolidines | 2004 |
The relationship between cell proliferation, Cl- secretion, and renal cyst growth: a study using CFTR inhibitors.
Topics: Animals; Benzoates; Cell Division; Cell Line; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dogs; Electric Conductivity; Epithelium; Genistein; Glyburide; Ion Transport; Kidney Diseases, Cystic; Nitrobenzoates; Thiazoles; Thiazolidines | 2004 |
Synthesis and biological evaluation of 2-aminothiazoles and their amide derivatives on human adenosine receptors. Lack of effect of 2-aminothiazoles as allosteric enhancers.
Topics: Allosteric Regulation; Amides; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Humans; Molecular Structure; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Structure-Activity Relationship; Thiazoles | 2005 |
CFTR-regulated chloride transport at the ocular surface in living mice measured by potential differences.
Topics: Amiloride; Animals; Benzoates; Chlorides; Colforsin; Conjunctiva; Cornea; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Ion Transport; Membrane Potentials; Mice; Mice, Inbred CFTR; Mice, Mutant Strains; Thiazoles; Thiazolidines | 2005 |
Theophylline stimulates cAMP-mediated signaling associated with growth regulation in human cells from pulmonary adenocarcinoma and small airway epithelia.
Topics: Adenocarcinoma; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Epithelial Cells; Humans; Immunoassay; Lung Neoplasms; MAP Kinase Signaling System; Muscle, Smooth; Phosphodiesterase Inhibitors; Phosphorylation; Signal Transduction; Tetrazolium Salts; Theophylline; Thiazoles; Time Factors; Trachea | 2005 |
Disruption of CFTR chloride channel alters mechanical properties and cAMP-dependent Cl- transport of mouse aortic smooth muscle cells.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta, Thoracic; Benzoates; Cells, Cultured; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Genistein; Glyburide; In Vitro Techniques; Isoproterenol; Mice; Mice, Inbred CFTR; Muscle, Smooth, Vascular; ortho-Aminobenzoates; Quinolizines; Serotonin; Thiazoles; Thiazolidines; Vasoactive Intestinal Peptide; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2005 |
Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening.
Topics: Animals; Cells, Cultured; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Design; Enzyme Inhibitors; Epithelial Cells; Genistein; Humans; Iodides; Luminescent Proteins; Molecular Structure; Mutation; Pyrimidinones; Respiratory Mucosa; Thiazoles | 2005 |
Induction of neuronal differentiation of adult human olfactory neuroepithelial-derived progenitors.
Topics: Adult; Aged, 80 and over; Analysis of Variance; Animals; Cell Differentiation; Cells, Cultured; Chick Embryo; Choline O-Acetyltransferase; Coculture Techniques; Colforsin; Drug Interactions; Female; Gene Expression Regulation, Developmental; Hedgehog Proteins; Humans; Indoles; Male; Muscle Cells; Neurites; Neurons; Olfactory Mucosa; Phosphopyruvate Hydratase; Stem Cells; Synapsins; Tetrazolium Salts; Thiazoles; Trans-Activators; Transcription Factors; Tretinoin; Tyrosine 3-Monooxygenase; Vesicular Acetylcholine Transport Proteins | 2006 |
Identification of new small molecule inhibitors of cystic fibrosis transmembrane conductance regulator protein: in vitro and in vivo studies.
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Apigenin; Bucladesine; Carbachol; Cell Line, Tumor; Chloride Channels; Cholera Toxin; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Humans; Intestinal Mucosa; Intestines; Jejunum; Luminescent Proteins; Mice; Mice, Inbred ICR; Molecular Structure; Phosphodiesterase Inhibitors; Rats; Sulfonamides; Tetrahydronaphthalenes; Thiazoles | 2007 |
Transcriptional regulation of corticotrophin releasing factor gene by furocoumarins isolated from seeds of Psoralea corylifolia.
Topics: Animals; Antidepressive Agents, Second-Generation; Cell Line; Cell Survival; Colforsin; Corticotropin-Releasing Hormone; Fluoxetine; Furocoumarins; Gene Expression Regulation; Mice; Promoter Regions, Genetic; Psoralea; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seeds; Tetrazolium Salts; Thiazoles | 2008 |
cAMP promotes neurite outgrowth and extension through protein kinase A but independently of Erk activation in cultured rat motoneurons.
Topics: Adenine; Animals; Cell Survival; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic CMP; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Motor Neurons; Neurites; Pregnancy; Rats; Rats, Sprague-Dawley; Spinal Cord; Tetrazolium Salts; Thiazoles | 2008 |
Induction of cells differentiation and ABC transporters expression by a myco-estrogen, zearalenone, in human choriocarcinoma cell line (BeWo).
Topics: ATP-Binding Cassette Transporters; Cell Differentiation; Cell Line, Tumor; Cell Survival; Choriocarcinoma; Colforsin; Coloring Agents; Dose-Response Relationship, Drug; Drug Combinations; Estradiol; Estrogens, Non-Steroidal; Female; Fluorescent Antibody Technique, Indirect; Humans; Pregnancy; Tetrazolium Salts; Thiazoles; Time Factors; Trophoblasts; Zearalenone | 2009 |
Characterization of the effect of TIMAP phosphorylation on its interaction with protein phosphatase 1.
Topics: Animals; Blotting, Western; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytoskeletal Proteins; Endothelial Cells; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Kinetics; Membrane Proteins; Microfilament Proteins; Microscopy, Fluorescence; Phosphorylation; Protein Binding; Protein Phosphatase 1; Surface Plasmon Resonance; Thiazoles; Urea | 2011 |
The antagonistic modulation of Arp2/3 activity by N-WASP, WAVE2 and PICK1 defines dynamic changes in astrocyte morphology.
Topics: Actin-Related Protein 2-3 Complex; Amides; Animals; Astrocytes; Carrier Proteins; Cells, Cultured; Central Nervous System; Colforsin; Enzyme Inhibitors; Fibroblasts; HEK293 Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Myosin Type II; Nuclear Proteins; Pyridines; Rats; rhoA GTP-Binding Protein; RNA Interference; RNA, Small Interfering; Thiazoles; Thiones; Uracil; Vasodilator Agents; Wiskott-Aldrich Syndrome Protein, Neuronal | 2013 |
Searching for combinations of small-molecule correctors to restore f508del-cystic fibrosis transmembrane conductance regulator function and processing.
Topics: 1-Deoxynojirimycin; Aminopyridines; Benzamides; Benzodioxoles; Cell Survival; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; HeLa Cells; Humans; Thiazoles | 2014 |
Direct Reprogramming of Glioblastoma Cells into Neurons Using Small Molecules.
Topics: Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Line, Tumor; Cellular Reprogramming; Cellular Reprogramming Techniques; Colforsin; Diamines; Glioblastoma; Heterocyclic Compounds, 4 or More Rings; Homeodomain Proteins; Humans; Isoxazoles; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurons; POU Domain Factors; Pyridines; Pyrimidines; Thiazoles; Thiophenes; Up-Regulation | 2018 |
Manipulation of Lipid Metabolism During Normothermic Machine Perfusion: Effect of Defatting Therapies on Donor Liver Functional Recovery.
Topics: Allografts; Anthracenes; Butyrates; Colforsin; Fatty Liver; Feasibility Studies; Female; Humans; Lipid Metabolism; Liver; Liver Transplantation; Male; Middle Aged; Nicotinamide Phosphoribosyltransferase; Organ Preservation; Perfusion; Perylene; Pharmaceutical Solutions; Phenylurea Compounds; Reperfusion Injury; Thiazoles; Tissue and Organ Harvesting | 2019 |