colforsin has been researched along with nociceptin in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (53.85) | 18.2507 |
| 2000's | 10 (38.46) | 29.6817 |
| 2010's | 2 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
| Ardati, A; Bourson, A; Bunzow, JR; Civelli, O; Grandy, DK; Henningsen, RA; Langen, H; Monsma, FJ; Nothacker, HP; Reinscheid, RK | 1 |
| Ardati, A; Civelli, O; Monsma, FJ; Reinscheid, RK | 1 |
| Hom, JS; Mathis, J; Mei, J; Pan, YX; Pasternak, GW; Ryan-Moro, J; Xu, J | 1 |
| Cai, YC; Cheng, ZJ; Fan, GH; Jiang, LZ; Ma, L; Pei, G | 1 |
| Butour, JL; Mazarguil, H; Meunier, JC; Moisand, C; Mollereau, C | 1 |
| Bianchi, C; Calo, G; Guerrini, R; Lazarus, LH; Regoli, D; Rizzi, A; Salvadori, S; Temussi, PA | 1 |
| Cheng, ZJ; Ling, K; Ma, L; Pei, G; Pu, L; Wu, YL; Zhao, J | 1 |
| Ma, L; Pei, G; Xin, SM; Zhang, Y; Zhao, J | 1 |
| Butour, JL; Lapalu, S; Meunier, JC; Moisand, C; Mollereau, C | 1 |
| Hirst, RA; Lambert, DG; McKnight, AT; Okawa, H; Smart, D | 1 |
| Butour, JL; Meunier, JC; Moisand, C; Mollereau, C | 1 |
| Allen, RG; Fujimoto, KI; Nelson, CS; Pellegrino, MJ; Sirianni, MJ | 1 |
| Ingianni, A; Maullu, C; Olianas, MC; Onali, P | 1 |
| Bao, GB; Ma, L; Pei, G; Pu, L | 1 |
| Galo', G; Guerrini, R; Harrison, C; Hashiba, E; Lambert, DG; Rowbotham, DJ; Smith, G | 1 |
| Ingianni, A; Olianas, MC; Onali, P | 1 |
| Aoki, Y; Asai, M; Iwasaki, Y; Mutsuga, N; Nomura, A; Oiso, Y; Saito, H; Yamamori, E; Yoshida, M | 1 |
| Olianas, MC; Onali, P | 1 |
| Brann, DW; Dhandapani, KM | 1 |
| Calo', G; Guerrini, R; Hashimoto, Y; Lambert, DG; Smith, G | 1 |
| Judd, AK; Kaushanskaya, A; Khroyan, T; Polgar, W; Sanchez, A; Toll, L; Tuttle, DJ | 1 |
| Barnes, TA; Calo, G; Carra, G; Guerrini, R; Kitayama, M; Lambert, DG; McDonald, J; Rowbotham, DJ; Smith, G | 1 |
| Boi, M; Dedoni, S; Olianas, MC; Onali, P | 1 |
| Alonso-Vanegas, M; Benyhe, S; Borsodi, A; Gaona, A; Orozco-Suarez, S; Páldy, E; Rocha, L; Villeda-Hernandez, J | 1 |
| Traynor, JR; Wang, Q | 1 |
26 other study(ies) available for colforsin and nociceptin
| Article | Year |
|---|---|
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.
Topics: Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Analgesics; Animals; CHO Cells; Colforsin; Cricetinae; GTP-Binding Proteins; Hypothalamus; Injections, Intraventricular; Injections, Spinal; Ligands; Mice; Molecular Sequence Data; Motor Activity; Nociceptin; Opioid Peptides; Pain Measurement; Receptors, Neuropeptide; Receptors, Opioid; Swine; Transfection | 1995 |
Structure-activity relationship studies on the novel neuropeptide orphanin FQ.
Topics: Amino Acid Sequence; Animals; Cell Line; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Humans; Kinetics; Ligands; Molecular Sequence Data; Nociceptin; Opioid Peptides; Peptides; Receptors, Neuropeptide; Recombinant Proteins; Signal Transduction; Structure-Activity Relationship; Transfection | 1996 |
Dissociation of affinity and efficacy in KOR-3 chimeras.
Topics: Animals; Base Sequence; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; DNA Primers; Exons; Kinetics; Mice; Models, Structural; Narcotics; Nerve Tissue Proteins; Nociceptin; Nociceptin Receptor; Opioid Peptides; Polymerase Chain Reaction; Protein Structure, Secondary; Receptors, Opioid; Receptors, Opioid, kappa; Recombinant Fusion Proteins; Restriction Mapping; Transfection | 1996 |
Functional expression, activation and desensitization of opioid receptor-like receptor ORL1 in neuroblastoma x glioma NG108-15 hybrid cells.
Topics: Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; GTP-Binding Proteins; Hybrid Cells; Naltrexone; Narcotic Antagonists; Neuroblastoma; Nociceptin; Nociceptin Receptor; Opioid Peptides; Pertussis Toxin; Receptors, Opioid; Receptors, Opioid, delta; Virulence Factors, Bordetella | 1997 |
Recognition and activation of the opioid receptor-like ORL 1 receptor by nociceptin, nociceptin analogs and opioids.
Topics: Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Analgesics, Opioid; Animals; Binding, Competitive; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Enzyme Inhibitors; Fentanyl; Molecular Sequence Data; Nociceptin; Nociceptin Receptor; Opioid Peptides; Receptors, Opioid | 1997 |
Address and message sequences for the nociceptin receptor: a structure-activity study of nociceptin-(1-13)-peptide amide.
Topics: Amino Acid Sequence; Animals; Colforsin; Cyclic AMP; Male; Mice; Molecular Sequence Data; Nociceptin; Nociceptors; Oligopeptides; Opioid Peptides; Peptide Fragments; Protein Conformation; Receptors, Opioid; Structure-Activity Relationship; Vas Deferens | 1997 |
Molecular characterization and functional expression of opioid receptor-like1 receptor.
Topics: Adenylyl Cyclase Inhibitors; Animals; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; Enzyme Inhibitors; Gene Expression; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydrogen-Ion Concentration; Ligands; Neuroblastoma; Nociceptin; Nociceptin Receptor; Opioid Peptides; Receptors, Opioid; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 1997 |
Attenuation of nociceptin/orphanin FQ-induced signaling by N-methyl-D-aspartate in neuronal cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hybrid Cells; Kinetics; Mice; N-Methylaspartate; Narcotic Antagonists; Neuroblastoma; Neurons; Nociceptin; Nociceptin Receptor; Opioid Peptides; Rats; Receptors, Opioid; Signal Transduction | 1998 |
Different domains of the ORL1 and kappa-opioid receptors are involved in recognition of nociceptin and dynorphin A.
Topics: Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dynorphins; Humans; Kinetics; Ligands; Narcotic Antagonists; Narcotics; Nociceptin; Nociceptin Receptor; Opioid Peptides; Protein Structure, Secondary; Receptors, Opioid; Receptors, Opioid, kappa; Recombinant Fusion Proteins | 1998 |
Rat central ORL-1 receptor uncouples from adenylyl cyclase during membrane preparation.
Topics: Animals; Brain Stem; Cannabinoids; Cell Membrane; Cerebellum; Cerebral Cortex; Colforsin; Cyclic AMP; Dronabinol; Female; Iodine Radioisotopes; Nociceptin; Nociceptin Receptor; Opioid Peptides; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Opioid; Rimonabant | 1998 |
[Phe1psi(CH2-NH)Gly2]nociceptin-(1-13)-NH2 is an agonist of the nociceptin (ORL1) receptor.
Topics: Animals; Cell Line, Transformed; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Humans; Nociceptin; Nociceptin Receptor; Opioid Peptides; Peptide Fragments; Receptors, Opioid | 1998 |
Cyclic AMP analogs induce synthesis, processing, and secretion of prepro nociceptin/orphanin FQ-derived peptides by NS20Y neuroblastoma cells.
Topics: Animals; Cell Size; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Dexamethasone; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Mice; Narcotics; Neurites; Neuroblastoma; Neurons; Nociceptin; Opioid Peptides; Peptide Fragments; Radioimmunoassay; Receptors, Opioid, delta; RNA, Messenger; Signal Transduction; Thionucleotides; Time Factors; Tumor Cells, Cultured | 1999 |
[Phe1phi(CH2-NH)Gly2]nociceptin-(1-13)-NH2 acts as a partial agonist at ORL1 receptor endogenously expressed in mouse N1E-115 neuroblastoma cells.
Topics: Animals; Colforsin; Cyclic AMP; Drug Combinations; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Neuroblastoma; Nociceptin; Nociceptin Receptor; Opioid Peptides; Peptide Fragments; Receptors, Opioid; Tumor Cells, Cultured | 1999 |
Acute desensitization of nociceptin/orphanin FQ inhibition of voltage-gated calcium channels in freshly dissociated hippocampal neurons.
Topics: Animals; Baclofen; Barium; Calcium; Calcium Channel Blockers; Calcium Channels, P-Type; Carcinogens; Cells, Cultured; Colforsin; Electrophysiology; Extracellular Space; GABA Agonists; Hippocampus; Ion Channel Gating; Membrane Potentials; Nociceptin; Opioid Peptides; Patch-Clamp Techniques; Peptide Fragments; Protein Kinase C; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tetrodotoxin | 1999 |
Characterisation and comparison of novel ligands for the nociceptin/orphanin FQ receptor.
Topics: Animals; Benzimidazoles; Binding, Competitive; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression; Humans; Imidazoles; Ligands; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Opioid Peptides; Peptide Fragments; Piperidines; Radioligand Assay; Receptors, Opioid; Spiro Compounds; Tritium | 2001 |
Dual coupling of opioid receptor-like (ORL1) receptors to adenylyl cyclase in the different layers of the rat main olfactory bulb.
Topics: Adenylyl Cyclases; Animals; Calcium; Calmodulin; Colforsin; Enzyme Activation; Gene Expression Regulation, Enzymologic; Guanosine 5'-O-(3-Thiotriphosphate); Isoenzymes; Male; Nociceptin; Nociceptin Receptor; Olfactory Bulb; Opioid Peptides; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid; RNA, Messenger; Sulfur Radioisotopes; Tritium; Vasodilator Agents | 2001 |
Effects of loperamide and other opioid-related substances on the transcriptional regulation of the rat pro-opiomelanocortin gene in AtT20 cells.
Topics: Animals; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Gene Expression; Loperamide; Mice; Naloxone; Nifedipine; Nociceptin; Oligopeptides; Opioid Peptides; Pro-Opiomelanocortin; Receptors, Opioid, mu; Sulfonamides; Time Factors | 2001 |
Pharmacological properties of nociceptin/orphanin FQ-induced stimulation and inhibition of cyclic AMP formation in distinct layers of rat olfactory bulb.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Excitatory Amino Acids; Male; Narcotic Antagonists; Nociceptin; Olfactory Bulb; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Vasodilator Agents | 2002 |
Orphanin FQ inhibits GnRH secretion from rat hypothalamic fragments but not GT1-7 neurons.
Topics: Animals; Cell Line, Transformed; Colforsin; Dose-Response Relationship, Drug; Gene Expression; Gonadotropin-Releasing Hormone; Hypothalamus; Male; Neurons; Nociceptin; Nociceptin Receptor; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 2002 |
Effects of chronic nociceptin/orphanin FQ exposure on cAMP accumulation and receptor density in Chinese hamster ovary cells expressing human nociceptin/orphanin FQ receptors.
Topics: Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Down-Regulation; Humans; Kinetics; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Opioid Peptides; Protease Inhibitors; Receptors, Cell Surface; Receptors, Opioid; Recombinant Proteins | 2002 |
N-terminal modifications leading to peptide ORL1 partial agonists and antagonists.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; CHO Cells; Colforsin; Cricetinae; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Mice; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Oligopeptides; Opioid Peptides; Pain; Receptors, Opioid; Sulfur Radioisotopes | 2003 |
Pharmacological profile of the cyclic nociceptin/orphanin FQ analogues c[Cys10,14]N/OFQ(1-14)NH2 and c[Nphe1,Cys10,14]N/OFQ(1-14)NH2.
Topics: Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cysteine; Dose-Response Relationship, Drug; Electric Stimulation; Female; GTP-Binding Proteins; Male; Mice; Muscle Contraction; Naloxone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Phenylalanine; Radioligand Assay; Rats; Rats, Wistar; Receptors, Opioid; Recombinant Proteins; Vas Deferens | 2003 |
Activation of nociceptin/orphanin FQ-NOP receptor system inhibits tyrosine hydroxylase phosphorylation, dopamine synthesis, and dopamine D(1) receptor signaling in rat nucleus accumbens and dorsal striatum.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Cells, Cultured; Colforsin; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Ethers; Gene Expression Regulation; Hydrocarbons, Fluorinated; Male; Neurons; Nociceptin; Nociceptin Receptor; Nucleus Accumbens; Opioid Peptides; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Opioid; Serine; Signal Transduction; Synaptosomes; Tyrosine 3-Monooxygenase | 2008 |
Temporal lobe epilepsy causes selective changes in mu opioid and nociceptin receptor binding and functional coupling to G-proteins in human temporal neocortex.
Topics: Adenylyl Cyclases; Adult; Central Nervous System Agents; Colforsin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Epilepsy, Temporal Lobe; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Middle Aged; Neocortex; Nociceptin; Nociceptin Receptor; Opioid Peptides; Receptors, Opioid; Receptors, Opioid, mu; Sulfur Radioisotopes; Temporal Lobe; Tritium; Young Adult | 2009 |
Modulation of μ-opioid receptor signaling by RGS19 in SH-SY5Y cells.
Topics: Adaptor Proteins, Signal Transducing; Adenylyl Cyclases; Animals; Benzamides; Colforsin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; HEK293 Cells; Humans; Mitogen-Activated Protein Kinases; Morphine; Nociceptin; Nociceptin Receptor; Opioid Peptides; PC12 Cells; Piperazines; Protein Kinase C; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; RGS Proteins; Signal Transduction | 2013 |