colforsin and naloxone

Topics: Animals; Drug Design; Humans; Receptors, Drug

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Atropine; Calcimycin; Calcium; Colforsin; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Evoked Potentials; Fentanyl; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Myenteric Plexus; Naloxone; Pyrrolidines; Receptors, Muscarinic; Receptors, Opioid; Sufentanil

Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Brain; Cell Membrane; Colforsin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine Triphosphate; Male; Naloxone; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sodium; Sodium Chloride; Sodium Fluoride

Topics: Adenylyl Cyclases; Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Colforsin; Cyclic AMP; Drug Implants; Drug Tolerance; Enzyme Activation; In Vitro Techniques; Mice; Morphine; Naloxone; Rats; Spinal Cord; Substance Withdrawal Syndrome; Synaptosomes

Topics: Animals; beta-Endorphin; Cell Survival; Cells, Cultured; Clone Cells; Colforsin; Concanavalin A; Cyclic AMP; Depression, Chemical; Dinoprostone; Dose-Response Relationship, Drug; Enkephalins; Female; Lymphocyte Activation; Lymphokines; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Protein Biosynthesis; Receptors, Opioid; Spleen; T-Lymphocytes, Helper-Inducer

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylate Cyclase Toxin; Animals; Antibodies, Monoclonal; Behavior, Animal; Bucladesine; Colforsin; Dose-Response Relationship, Drug; Electroencephalography; Humans; Interleukin-2; Locus Coeruleus; Male; Microinjections; Naloxone; Pertussis Toxin; Rats; Rats, Inbred Strains; Recombinant Proteins; Virulence Factors, Bordetella; Yohimbine

Topics: Analgesics; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Fentanyl; Guinea Pigs; In Vitro Techniques; Myenteric Plexus; Naloxone; Narcotics; Parasympatholytics; Sufentanil; Thionucleotides; Virulence Factors, Bordetella

Topics: Action Potentials; Animals; Cesium; Colforsin; Enkephalins; Guinea Pigs; In Vitro Techniques; Ion Channels; Naloxone; Neurons; Norepinephrine; Potassium; Rubidium; Somatostatin; Submucous Plexus; Thionucleotides; Time Factors

Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Membrane; Cerebellum; Colforsin; Corpus Striatum; Dynorphins; Guanine Nucleotides; Guinea Pigs; Hydrogen-Ion Concentration; Naloxone; Receptors, Opioid; Receptors, Opioid, kappa; Sodium

Topics: Action Potentials; Animals; Colforsin; Cyclic AMP; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Fentanyl; Guinea Pigs; Myenteric Plexus; Naloxone; Sufentanil

Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Brain; Cell Membrane; Cholera Toxin; Colforsin; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; GTP-Binding Proteins; Guanine Nucleotides; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; Male; Naloxone; Oligopeptides; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Fluoride; Virulence Factors, Bordetella

Topics: Adenylyl Cyclases; Age Factors; Animals; Chick Embryo; Colforsin; Enzyme Activation; Isoproterenol; Morphine; Naloxone; Neurotransmitter Agents; Norepinephrine; Sodium Fluoride

Topics: Adenosine Triphosphatases; Adenylyl Cyclases; Animals; Brain Ischemia; Cerebrovascular Circulation; Colforsin; Female; Frontal Lobe; Gerbillinae; Guanine Nucleotides; In Vitro Techniques; Morphine; Motor Activity; Naloxone; Norepinephrine

Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Benzazepines; Colforsin; Corpus Striatum; Cyclic AMP; Drug Interactions; In Vitro Techniques; Morphine; Naloxone; Rats

Topics: Animals; Cell Line; Colforsin; Enkephalin, Methionine; Enkephalins; Etorphine; Genes; Glioma; Hybrid Cells; Morphinans; Morphine; Naloxone; Neuroblastoma; Protein Precursors; RNA, Messenger; Transcription, Genetic

Topics: Animals; Calcium; Catecholamines; Colforsin; Diterpenes; Enkephalin, Leucine; Heart; Heart Rate; Isoproterenol; Male; Naloxone; Norepinephrine; Rats; Receptors, Adrenergic

Topics: Analgesics; Animals; Colforsin; Corpus Striatum; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gene Expression; Male; Models, Molecular; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors

Topics: Animals; Cell Line; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; Dynorphins; Evoked Potentials; Female; Humans; Kinetics; Ligands; Naloxone; Narcotic Antagonists; Narcotics; Oocytes; Receptors, Opioid; Recombinant Proteins; Xenopus laevis

Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Migration Inhibition; Cell Movement; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enkephalin, Leucine; Female; In Vitro Techniques; Mice; Mice, Inbred CBA; Naloxone; Spleen; Theophylline

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Benzeneacetamides; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Etorphine; GTP-Binding Proteins; Naloxone; Naltrexone; Opioid Peptides; Pertussis Toxin; Pyrrolidines; Receptors, Opioid, kappa; Virulence Factors, Bordetella

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylate Cyclase Toxin; Animals; Calcium; Colforsin; Cyclic AMP; Egtazic Acid; Naloxone; Oocytes; Patch-Clamp Techniques; Pertussis Toxin; Pyrrolidines; Receptors, Opioid; Virulence Factors, Bordetella; Xenopus

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclases; Amino Acid Sequence; Animals; Binding, Competitive; Cerebellum; Colforsin; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; GTP-Binding Proteins; Guinea Pigs; Humans; Hybrid Cells; Molecular Sequence Data; Morphine; Naloxone; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Oligopeptides; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured

Topics: Adenylyl Cyclases; Animals; Cell Line; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; DNA, Complementary; Guanylyl Imidodiphosphate; Morphine; Naloxone; Phosphatidylinositols; Rats; Receptors, Opioid, mu; Recombinant Proteins; Second Messenger Systems

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Base Sequence; Benzeneacetamides; Binding Sites; Cell Line; Chlorocebus aethiops; Cloning, Molecular; Colforsin; Cyclic AMP; Enkephalin, Leucine; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Naltrexone; Oligodeoxyribonucleotides; Protein Structure, Secondary; Pyrrolidines; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Recombinant Fusion Proteins; Recombinant Proteins; Transfection

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Cell Communication; Cells, Cultured; Colforsin; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Ganglia, Spinal; Isoproterenol; Kinetics; Male; Morphine; Naloxone; Neurons; Phosphates; Phosphoproteins; Phosphorylation; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid; Serotonin; Spinal Cord; Synapsins; Synaptosomes

Topics: Animals; Autoradiography; Benzazepines; Brain; Colforsin; Gerbillinae; Ischemic Attack, Transient; Male; Naloxone; Radioligand Assay; Time Factors

Topics: Adenosine Triphosphatases; Adenylyl Cyclases; Animals; Body Temperature; Brain; Brain Chemistry; Colforsin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethanol; Female; Levorphanol; Male; Mice; Mice, Inbred Strains; Naloxone; Nerve Tissue Proteins; Receptors, Opioid, mu

Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Analgesics; Analgesics, Opioid; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Kinetics; Morphine; Naloxone; Pertussis Toxin; Phosphodiesterase Inhibitors; Rats; Receptors, Opioid, mu; Recombinant Proteins; Transfection; Virulence Factors, Bordetella

Topics: Adenylyl Cyclases; Analgesics; Analysis of Variance; Animals; Binding, Competitive; Brain; Carbachol; Cell Line; Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanylyl Imidodiphosphate; Guinea Pigs; Haloperidol; Humans; Kinetics; Morphine; Naloxone; Neuroblastoma; Pentazocine; Phosphatidylinositols; Receptors, Opioid; Receptors, sigma; Trypsin; Tumor Cells, Cultured

Topics: Adenylate Cyclase Toxin; Adrenergic alpha-Agonists; Animals; Blood Pressure; Colforsin; Cyclic AMP; Enkephalin, Leucine; Ethanolamines; GTP-Binding Proteins; Heart; Male; Myocardium; Naloxone; Narcotic Antagonists; Norepinephrine; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Opioid, delta; Sarcolemma; Second Messenger Systems; Systole; Thionucleotides; Ventricular Function, Left; Virulence Factors, Bordetella

Topics: Adenine; Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cholera Toxin; Clone Cells; Colforsin; Cyclic AMP; Electrophysiology; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Kinetics; Mice; Naloxone; Narcotic Antagonists; Pertussis Toxin; Rats; Receptors, Opioid, delta; Recombinant Proteins; Transfection; Virulence Factors, Bordetella

Topics: Adenylyl Cyclases; Alprostadil; Cell Line; Colforsin; GTP-Binding Protein alpha Subunits, Gs; Humans; Hybrid Cells; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Receptors, Opioid, delta; Receptors, Prostaglandin; Signal Transduction; Substance Withdrawal Syndrome

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Binding, Competitive; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diprenorphine; DNA, Complementary; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP Phosphohydrolases; Naloxone; Receptors, Cell Surface; Receptors, Opioid; Transfection

Topics: Animals; Binding, Competitive; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diprenorphine; Excitatory Amino Acid Antagonists; Ketamine; Naloxone; Narcotic Antagonists; Opioid Peptides; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Proteins; Stereoisomerism

Topics: Adenylyl Cyclases; Alkaloids; Analgesics, Opioid; Animals; Benzophenanthridines; Colforsin; Cyclic AMP; Enkephalin, Leucine-2-Alanine; Enzyme Inhibitors; Hybrid Cells; Methadone; Mice; Morphine; Naloxone; Narcotic Antagonists; Phenanthridines; Protein Kinase C; Rats; Receptors, Opioid, delta; Time Factors; Tumor Cells, Cultured

Topics: Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Chromones; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Indoles; Maleimides; Morphine; Morpholines; Naloxone; Narcotic Antagonists; Narcotics; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Receptors, Opioid, mu; Recombinant Proteins; Thionucleotides; Transfection; Wortmannin

Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acid Substitution; Animals; Aspartic Acid; Binding, Competitive; Chlorocebus aethiops; Codon; Colforsin; COS Cells; Cyclic AMP; Diprenorphine; DNA, Complementary; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Ligands; Mice; Mutagenesis, Site-Directed; Naloxone; Pertussis Toxin; Point Mutation; Protein Binding; Receptors, Opioid, delta; Recombinant Fusion Proteins; Second Messenger Systems; Transfection; Virulence Factors, Bordetella

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Autocrine Communication; Calcium; Calcium Channels, L-Type; Cattle; Cells, Cultured; Chromaffin Cells; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enzyme Inhibitors; GABA Antagonists; Isoquinolines; Kinetics; Naloxone; Narcotic Antagonists; Patch-Clamp Techniques; Picrotoxin; Protein Kinase Inhibitors; Sulfonamides; Suramin

Topics: Animals; Behavior, Animal; Catalepsy; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Administration Routes; Dyskinesia, Drug-Induced; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Globus Pallidus; Humans; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Oligopeptides; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Transfection

Topics: Antidiarrheals; Calcium Channel Blockers; Calmodulin; Carbachol; Chlorides; Cholinergic Agonists; Colforsin; Colon; Drug Evaluation, Preclinical; Enterocytes; HT29 Cells; Humans; Intestinal Mucosa; Loperamide; Naloxone; Narcotic Antagonists; Potassium Channels; Signal Transduction; Time Factors; Trifluoperazine; Verapamil

Topics: Animals; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Gene Expression; Loperamide; Mice; Naloxone; Nifedipine; Nociceptin; Oligopeptides; Opioid Peptides; Pro-Opiomelanocortin; Receptors, Opioid, mu; Sulfonamides; Time Factors

Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Body Temperature Regulation; Colforsin; Male; Meperidine; Mice; Mice, Inbred C57BL; Naloxone; Receptors, Adrenergic, alpha-2; Shivering; Structure-Activity Relationship

Topics: Analgesics, Opioid; Colforsin; Cyclic AMP; Drug Interactions; Humans; Morphine; Naloxone; Narcotic Antagonists; Neuroblastoma; Oligopeptides; Receptors, Opioid, mu; RNA, Messenger; Tumor Cells, Cultured

Topics: Action Potentials; Adenosine; Affinity Labels; Animals; Colforsin; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Enkephalins; Enzyme Inhibitors; gamma-Aminobutyric Acid; In Vitro Techniques; Isoquinolines; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Probenecid; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Substance Withdrawal Syndrome; Sulfonamides; Synaptic Transmission; Thioinosine; Time Factors; Uricosuric Agents; Vasodilator Agents; Xanthines

Topics: Animals; Binding, Competitive; Blotting, Western; Cell Line; Cloning, Molecular; Colforsin; Copper Sulfate; Cyclic AMP; Diprenorphine; DNA, Complementary; Drosophila; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Gene Expression; Genetic Vectors; Green Fluorescent Proteins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Luminescent Proteins; Metallothionein; Microscopy, Confocal; Morphine; Naloxone; Naltrexone; Oligopeptides; Opioid Peptides; Pertussis Toxin; Polymerase Chain Reaction; Protein Binding; Receptors, G-Protein-Coupled; Receptors, Opioid, mu; Recombinant Fusion Proteins; Spectrometry, Fluorescence; Thermodynamics

Topics: Animals; Cells, Cultured; Colforsin; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Agonists; Enzyme Inhibitors; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Phosphorylation; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance Withdrawal Syndrome

Topics: Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cysteine; Dose-Response Relationship, Drug; Electric Stimulation; Female; GTP-Binding Proteins; Male; Mice; Muscle Contraction; Naloxone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Phenylalanine; Radioligand Assay; Rats; Rats, Wistar; Receptors, Opioid; Recombinant Proteins; Vas Deferens

Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Animals, Newborn; Behavior, Animal; Blotting, Western; Colforsin; Cyclic AMP; Dose-Response Relationship, Radiation; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Imines; In Vitro Techniques; Isoquinolines; Male; Membrane Potentials; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Oxidoreductases; Pain; Pain Measurement; Patch-Clamp Techniques; Pyrimidines; Raphe Nuclei; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides

Topics: Analgesics, Opioid; Animals; Annexin A5; Blotting, Western; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Gene Expression Regulation; Humans; Immunohistochemistry; Naloxone; Narcotic Antagonists; Narcotics; Oligonucleotide Array Sequence Analysis; PC12 Cells; Protein Binding; Radioligand Assay; Rats; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection

Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Enzyme Activation; Humans; Indoles; Morphine; Naloxone; Narcotic Antagonists; Phenols; Proto-Oncogene Proteins c-raf; Receptors, Opioid, mu; Transfection

Topics: Analgesics, Opioid; Colforsin; Cyclic AMP; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Morphine; Naloxone; Narcotic Antagonists; NF-kappa B; Protein Binding; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Naloxone; Narcotic Antagonists; Papillary Muscles; Phosphodiesterase 3 Inhibitors; Phosphodiesterase Inhibitors

Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Animals; Calcitonin; Cell Culture Techniques; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Female; Humans; Inhibitory Concentration 50; Ligands; Molecular Targeted Therapy; Naloxone; Narcotic Antagonists; Phosphodiesterase Inhibitors; Radioligand Assay; Rats; Receptors, Calcitonin; Receptors, G-Protein-Coupled; Receptors, Islet Amyloid Polypeptide; Receptors, Opioid, mu; Salmon

Topics: Analysis of Variance; Cell Line, Tumor; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Hormone Antagonists; Humans; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neuroblastoma; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Receptors, Opioid, mu; RNA, Messenger; Sincalide; Up-Regulation

Topics: Alprostadil; Biological Transport; Cadmium Chloride; Chloride Channels; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Lubiprostone; Methadone; Morphine; Naloxone; Patch-Clamp Techniques; Recombinant Proteins; Time Factors; Transfection

Topics: Analysis of Variance; Astrocytoma; Cell Line, Tumor; Colforsin; Cyclic AMP; Drug Interactions; Gene Expression Regulation, Neoplastic; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neuroblastoma; Oligopeptides; Radioimmunoassay; Receptors, Opioid; RNA, Messenger; Time Factors; Up-Regulation