Compounds > colforsin
Page last updated: 2024-08-23

colforsin and lumacaftor

colforsin has been researched along with lumacaftor in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Becq, F; Boinot, C; Ferru-Clément, R; Jollivet Souchet, M1
Aban, I; Boyles, SE; Chaudhry, IG; Chua, M; Gentzsch, M; Guimbellot, JS; Jaspers, I; Leach, JM; Quinney, NL1
Boyles, SE; Cholon, DM; Gentzsch, M; Martino, MEB; Quinney, NL; Ribeiro, CMP1
Bijvelds, MJC; Bose, SJ; Bot, AGM; Cai, Z; de Jonge, HR; Liu, J; Sheppard, DN; Wang, Y1
Hanrahan, JW; Luo, Y; Thomas, DY; Turner, MJ1

Other Studies

5 other study(ies) available for colforsin and lumacaftor

ArticleYear
Searching for combinations of small-molecule correctors to restore f508del-cystic fibrosis transmembrane conductance regulator function and processing.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 350, Issue:3

    Topics: 1-Deoxynojirimycin; Aminopyridines; Benzamides; Benzodioxoles; Cell Survival; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; HeLa Cells; Humans; Thiazoles

2014
Nasospheroids permit measurements of CFTR-dependent fluid transport.
    JCI insight, 2017, 11-16, Volume: 2, Issue:22

    Topics: Aminophenols; Aminopyridines; Benzodioxoles; Biological Transport; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Combinations; Humans; Mutation; Nasal Mucosa; Particle Size; Precision Medicine; Quinolones; Spheroids, Cellular

2017
The cystic fibrosis airway milieu enhances rescue of F508del in a pre-clinical model.
    The European respiratory journal, 2018, Volume: 52, Issue:6

    Topics: Aminophenols; Aminopyridines; Benzodioxoles; Bronchi; Cell Line; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Humans; Inflammation; Mutation; Quinolones; Respiratory System

2018
Differential thermostability and response to cystic fibrosis transmembrane conductance regulator potentiators of human and mouse F508del-CFTR.
    American journal of physiology. Lung cellular and molecular physiology, 2019, 07-01, Volume: 317, Issue:1

    Topics: Adenosine Triphosphate; Aminophenols; Aminopyridines; Animals; Base Sequence; Benzodioxoles; Chloride Channel Agonists; CHO Cells; Colforsin; Cricetulus; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Gene Expression; Genistein; Ion Transport; Mice; NIH 3T3 Cells; Patch-Clamp Techniques; Protein Stability; Quinolones; Sequence Deletion; Species Specificity; Temperature; Transgenes

2019
The dual phosphodiesterase 3/4 inhibitor RPL554 stimulates rare class III and IV CFTR mutants.
    American journal of physiology. Lung cellular and molecular physiology, 2020, 05-01, Volume: 318, Issue:5

    Topics: Aminopyridines; Animals; Benzodioxoles; Bronchi; Cell Line; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Isoquinolines; Mutation; Phosphodiesterase 3 Inhibitors; Phosphodiesterase 4 Inhibitors; Primary Cell Culture; Pyrimidinones; Rats; Rats, Inbred F344; Thyroid Epithelial Cells; Transgenes

2020