colforsin has been researched along with iloprost in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (16.07) | 18.7374 |
| 1990's | 32 (57.14) | 18.2507 |
| 2000's | 11 (19.64) | 29.6817 |
| 2010's | 4 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schröder, H; Schrör, K; Strobach, H | 1 |
| Austin, A; Docherty, K; Keen, M; Kelly, E; Krane, A; MacDermot, J; Taylor, N; Wiltshire, R | 1 |
| Conanan, LB; Crutchley, DJ; Solomon, DE | 1 |
| Keen, M; Kelly, E; MacDermot, J; Nobbs, P | 1 |
| De Mey, JG; Dijkstra, EH; Vrijdag, MJ | 1 |
| Langeler, EG; van Hinsbergh, VW | 1 |
| Bosia, A; Bussolino, F; Garbarino, G; Ghigo, D; Heller, R; Pescarmona, G; Schröder, H; Till, U | 1 |
| Lowe, C; Skinner, SJ; Somervell, CE | 1 |
| Buzzi, E; Colao, C; Leoncini, G; Maresca, M; Mazzei, M | 1 |
| Daiss, W; Faul, C; Jaschonek, K; Weisenberger, H | 1 |
| Björnsson, OG; Kobayashi, K; Williamson, JR | 1 |
| Faul, C; Jaschonek, K; Renn, W; Schmidt, H | 1 |
| Colman, RW; Grant, PG; Mannarino, AF | 1 |
| Lapetina, EG; Lazarowski, ER | 1 |
| Colman, RF; Colman, RW; Puri, RN; Zhou, FX | 1 |
| Ollivier-Bousquet, M | 1 |
| Ashby, B | 1 |
| Müller, B; Schmidtke, M; Witt, W | 1 |
| Keen, M; Krane, A; Malkhandi, J; Mercy, L | 1 |
| Alessio, P; Bussolino, F; Calvino, R; Fruttero, R; Gasco, A; Ghigo, D; Heller, R; Pescarmona, G; Till, U; Todde, R | 1 |
| Bernabei, A; Edmunds, LH; Gikakis, N; Kowalska, MA; Niewiarowski, S | 1 |
| Bönisch, D; Grosser, T; Schrör, K; Zucker, TP | 1 |
| Carr, IC; Kim, GD; Milligan, G | 1 |
| Cader, MZ; Keen, M | 1 |
| Kim, GD; Milligan, G | 1 |
| Harrison, PK; Kelly, E; Williams, RJ | 1 |
| Onaya, T; Shindo, H; Tawata, M | 1 |
| Conanan, LB; Crutchley, DJ; Que, BG; Solomon, DE; Toledo, AW | 1 |
| Glenn, J; Hardy, E; Heptinstall, S; Horn, EH; Rubin, PC | 1 |
| Hashimoto, Y; Kurokawa, K; Satoh, H; Taniguchi, S; Togoh, M; Watanabe, T | 1 |
| Ashby, B; Bastepe, M; Jin, JG; Mao, GF; Ortiz-Vega, S | 1 |
| Advenier, C; Dumas, JP; Dumas, M; Giudicelli, JF; Rochette, L | 1 |
| Bruggeman, CA; Couwenberg, FM; Heemskerk, JW; Hulsbosch, MM; Slobbe-van Drunen, ME; van Dam-Mieras, MC; Vossen, RC | 1 |
| Nakagawa, O; Nakamura, K; Nakao, K; Narumiya, S; Okuno, Y; Sasaki, Y; Takahashi, T; Tanaka, I | 1 |
| Bouchard, JF; Dumont, EC; Lamontagne, D | 1 |
| Chen, Y; D'Angelo, G; Michel, JB; Pueyo, ME | 1 |
| Lang, U; Vischer, UM; Wollheim, CB | 1 |
| Middleton, A; Middleton, B | 1 |
| Glenn, JR; Heptinstall, S | 1 |
| Frisbee, JC; Lombard, JH; Weber, DS | 1 |
| Frisbee, JC; Lombard, JH | 1 |
| Kao, C; Rowlands, DK; Wise, H | 1 |
| Akkerman, JW; den Dekker, E; Donath, J; Gorter, G; Heemskerk, JW; Kroner, C; Mikoshiba, K; van der Vuurst, H | 1 |
| Hagino, Y; Hishida, H; Ichinose, H; Itoh, M; Kato, T; Kuroda, R; Nagatsu, T; Nomura, T; Ohtsuki, M; Shiraishi, H; Sumi-Ichinose, C; Tada, S; Tazawa, M; Udagawa, Y | 1 |
| Frisbee, JC; Lombard, JH; Phillips, SA; Sylvester, FA | 1 |
| Fischer, JW; Meyer-Kirchrath, J; Nüsing, RM; Sarbia, M; Schrör, K; Sussmann, M | 1 |
| Cindrova-Davies, T; Li, RC; Sellers, LA; Skepper, JN | 1 |
| Lonigro, AJ; Olearczyk, JJ; Sprague, RS; Stephenson, AH | 1 |
| Bretschneider, E; Censarek, P; Fischer, JW; Meyer-Kirchrath, J; Pape, R; Rabausch, K; Sarbia, M; Schrör, K; Weber, AA | 1 |
| Breitenbach, SC; Ghofrani, HA; Grimminger, F; Kirchrath, JM; Nilius, SM; Pullamsetti, SS; Rose, F; Schermuly, RT; Schrör, K; Seeger, W; Weissmann, N | 1 |
| Bradbury, D; Clarke, DL; Clayton, A; Deacon, K; El-Haroun, H; Knox, AJ; Sutcliffe, A | 1 |
| Chang, HW; Chu, YT; Hung, CH; Jong, YJ; Lee, MS; Lo, YC; Suen, JL | 1 |
| Adderley, SP; Bowles, EA; Ellsworth, ML; Sprague, RS; Sridharan, M; Stephenson, AH | 1 |
| Choi, S; Joo, KY; Jung, JC; Kim, JA; Kim, MY; Oh, S; Park, S; Suh, SH | 1 |
| Basma, H; Fahrid, M; Gunji, Y; Holz, O; Kanaji, N; Liu, X; Magnussen, H; Michalski, J; Muller, KC; Nakanishi, M; Nelson, A; Nogel, S; Rabe, KF; Rennard, SI; Sato, T; Toews, ML; Wang, X | 1 |
| Limjeerajarus, CN; Manokawinchoke, J; Osathanon, T; Pavasant, P | 1 |
56 other study(ies) available for colforsin and iloprost
| Article | Year |
|---|---|
Nitric oxide but not prostacyclin is an autocrine endothelial mediator.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Endothelium, Vascular; Epoprostenol; Iloprost; Nitric Oxide; omega-N-Methylarginine; Second Messenger Systems; Swine | 1992 |
Cyclic AMP produces desensitization of prostacyclin and adenosine A2 receptors in hybrid cell lines but does not affect Gs function.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Epoprostenol; GTP-Binding Proteins; Iloprost; Magnesium; Receptors, Purinergic; RNA, Messenger | 1992 |
Prostacyclin analogues inhibit tissue factor expression in the human monocytic cell line THP-1 via a cyclic AMP-dependent mechanism.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Colforsin; Cyclic AMP; Endotoxins; Epoprostenol; Fluorescent Antibody Technique; Humans; Iloprost; Interleukin-1; Monocytes; Prostaglandins, Synthetic; Thromboplastin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1992 |
NaF and guanine nucleotides modulate adenylate cyclase activity in NG108-15 cells by interacting with both Gs and Gi.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cell Membrane; Colforsin; Enzyme Activation; Epoprostenol; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Iloprost; Mice; Morphine; Nervous System Neoplasms; Neuroblastoma; Pertussis Toxin; Sodium Fluoride; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Endothelium reduces DNA synthesis in isolated arteries.
Topics: Acetylcholine; Animals; Atrial Natriuretic Factor; Bromodeoxyuridine; Colforsin; Culture Techniques; Cyclic AMP; Cyclic GMP; Dinoprostone; DNA; Endothelium, Vascular; Iloprost; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Potassium; Rats; Rats, Inbred WKY; Renal Artery; Sympathectomy | 1991 |
Norepinephrine and iloprost improve barrier function of human endothelial cell monolayers: role of cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Aorta; Cells, Cultured; Colforsin; Cyclic AMP; Electric Conductivity; Endothelium, Vascular; Fluorescent Antibody Technique; Horseradish Peroxidase; Humans; Iloprost; Isoproterenol; Kinetics; Norepinephrine; Phentolamine; Propranolol; Umbilical Arteries; Venae Cavae | 1991 |
Protein kinase C and cyclic AMP modulate thrombin-induced platelet-activating factor synthesis in human endothelial cells.
Topics: Acetyltransferases; Arachidonic Acid; Arachidonic Acids; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascular; Humans; Iloprost; Ionomycin; Kinetics; Platelet Activating Factor; Protein Kinase C; Tetradecanoylphorbol Acetate; Thrombin | 1991 |
Interaction between prostacyclin and cortisol in fetal lung cells: effects on cAMP production.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Aorta; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Epithelial Cells; Epithelium; Fibroblasts; Hydrocortisone; Iloprost; Lung; Muscle, Smooth, Vascular; Rats; RNA; Virulence Factors, Bordetella | 1991 |
Mode of action of 2-(diethylamino)-7-ethoxychromone on human platelets.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Chromones; Colforsin; Collagen; Cyclic AMP; Humans; Iloprost; Phosphoric Diester Hydrolases; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Thrombin; Thromboxane A2 | 1991 |
Effects of heparin on prostacyclin binding and platelet adenylate cyclase activity stimulated by iloprost and forskolin.
Topics: Adenylyl Cyclases; Blood Platelets; Colforsin; Cresols; Cyclic AMP; Epoprostenol; Heparin; Humans; Iloprost; In Vitro Techniques; Platelet Aggregation | 1986 |
Inducers of adenylate cyclase reverse the effect of leukotriene D4 in isolated working guinea pig heart.
Topics: Adenosine; Adenylyl Cyclases; Animals; Colforsin; Enzyme Induction; Epoprostenol; Fluorometry; Guinea Pigs; Heart; Iloprost; Ischemia; Male; Myocardium; NAD; Oxygen Consumption; SRS-A; Vasoconstriction | 1987 |
Desensitization of platelets to iloprost. Loss of specific binding sites and heterologous desensitization of adenylate cyclase.
Topics: Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Blood Platelets; Cardiovascular Agents; Colforsin; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Epoprostenol; Humans; Iloprost; In Vitro Techniques; Kinetics; Phosphorus Radioisotopes; Ribose | 1988 |
cAMP-mediated phosphorylation of the low-Km cAMP phosphodiesterase markedly stimulates its catalytic activity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Blood Platelets; Colforsin; Cyclic AMP; Enzyme-Linked Immunosorbent Assay; Epoprostenol; Female; Iloprost; Immune Sera; Kinetics; Phosphorylation; Rabbits | 1988 |
Activation of platelet phospholipase C by fluoride is inhibited by elevation of cyclic AMP.
Topics: Blood Platelets; Bucladesine; Colforsin; Cyclic AMP; Enzyme Activation; Epoprostenol; Fluorides; Humans; Iloprost; In Vitro Techniques; Phosphatidic Acids; Phosphatidylinositols; Platelet Aggregation; Type C Phospholipases | 1989 |
Cleavage of a 100 kDa membrane protein (aggregin) during thrombin-induced platelet aggregation is mediated by the high affinity thrombin receptors.
Topics: Calpain; Colforsin; Cyclic AMP; Epoprostenol; Iloprost; Membrane Proteins; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, Thrombin; Thrombin | 1989 |
The actions of forskolin, cholera toxin and iloprost on casein secretion by lactating doe mammary glands.
Topics: Animals; Caseins; Cholera Toxin; Colforsin; Cyclic AMP; Deer; Epoprostenol; Female; Iloprost; In Vitro Techniques; Mammary Glands, Animal; Prolactin; Radioimmunoassay | 1989 |
Model of prostaglandin-regulated cyclic AMP metabolism in intact platelets: examination of time-dependent effects on adenylate cyclase and phosphodiesterase activities.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Blood Platelets; Colforsin; Computer Simulation; Cyclic AMP; Epoprostenol; GTP-Binding Proteins; Humans; Iloprost; Prostaglandins E; Time Factors | 1989 |
Adherence of leucocytes to electrically damaged venules in vivo. Effects of iloprost, PGE1, indomethacin, forskolin, BW 755 C, sulotroban, hirudin, and thrombocytopenia.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Alprostadil; Animals; Cell Adhesion; Colforsin; Electric Stimulation; Epoprostenol; Hirudins; Iloprost; Indomethacin; Leukocytes; Male; Mesenteric Veins; Rats; Rats, Inbred Strains; Sulfonamides; Thrombocytopenia; Venules | 1988 |
The role of protein kinase A and protein kinase C in prostanoid IP receptor desensitization in NG108-15 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Guanylyl Imidodiphosphate; Hybrid Cells; Iloprost; Isoquinolines; Mice; Piperazines; Protein Kinase C; Rats; Receptors, Prostaglandin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
S35b, a new phenylsulfonylfuroxan compound, inhibits thrombin-induced synthesis of platelet-activating factor and prostacyclin in human endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Acetyltransferases; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Humans; Iloprost; Oxadiazoles; Platelet Activating Factor; Platelet Aggregation Inhibitors; Thrombin; Umbilical Veins | 1993 |
Iloprost and echistatin protect platelets during simulated extracorporeal circulation.
Topics: Adenosine Diphosphate; beta-Thromboglobulin; Blood Platelets; Cardiopulmonary Bypass; Colforsin; Cyclic AMP; Epinephrine; Humans; Iloprost; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Oligopeptides; Peptides; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Viper Venoms | 1995 |
Iloprost-induced inhibition of proliferation of coronary artery smooth muscle cells is abolished by homologous desensitization.
Topics: Alprostadil; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cell Division; Cells, Cultured; Colforsin; Coronary Vessels; Female; Fluorides; Iloprost; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Time Factors | 1995 |
Detection and analysis of agonist-induced formation of the complex of the stimulatory guanine nucleotide-binding protein with adenylate cyclase in intact wild-type and beta 2-adrenoceptor-expressing NG108-15 cells.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Binding, Competitive; Cell Line; Cell Membrane; Colforsin; Enkephalin, Leucine-2-Alanine; GTP-Binding Proteins; Humans; Iloprost; Immunologic Techniques; Isoproterenol; Molecular Sequence Data; Peptides; Propranolol; Receptors, Adrenergic, beta; Recombinant Proteins; Signal Transduction; Transfection | 1995 |
The effect of colchicine on cyclic AMP accumulation in NG108-15 cells.
Topics: Animals; Cell Line; Colchicine; Colforsin; Cyclic AMP; Glioma; GTP-Binding Proteins; Hybrid Cells; Iloprost; Kinetics; Mice; Neuroblastoma; Rats; Receptors, Prostaglandin; Tumor Cells, Cultured | 1995 |
Agonist regulation of high affinity [3H] forskolin binding as a measure of GS alpha-adenylyl cyclase interactions.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Binding, Competitive; Cell Membrane; Colforsin; Glioma; GTP-Binding Proteins; Homeostasis; Hybrid Cells; Iloprost; Kinetics; Mice; Neuroblastoma; Rats; Signal Transduction; Tumor Cells, Cultured | 1995 |
Effects of acute and chronic ethanol on cyclic AMP accumulation in NG108-15 cells: differential dependence of changes on extracellular adenosine.
Topics: Adenosine; Adenosine Deaminase; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Ethanol; Iloprost; Mice; Neuroblastoma; Rats; Tumor Cells, Cultured | 1995 |
Reduction of cyclic AMP in the sciatic nerve of rats made diabetic with streptozotocin and the mechanism involved.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Colforsin; Culture Techniques; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glucose; Iloprost; Male; Motor Neurons; Neural Conduction; Rats; Rats, Wistar; Sciatic Nerve | 1993 |
Effects of prostacyclin analogues on human endothelial cell tissue factor expression.
Topics: Cells, Cultured; Colforsin; Culture Media, Conditioned; Cyclic AMP; Cytokines; Endothelium, Vascular; Epoprostenol; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Iloprost; Interleukin-1; Monocytes; Thromboplastin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Magnesium modifies the responses of platelets to inhibitory agents which act via cAMP.
Topics: Blood Platelets; Colforsin; Cyclic AMP; Drug Interactions; Female; Humans; Iloprost; Magnesium; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin D2; Quinazolines; Signal Transduction | 1995 |
Positive and negative regulation of cell proliferation through prostaglandin receptors in NIH-3T3 cells.
Topics: 3T3 Cells; Animals; Blotting, Northern; Calcium; Cell Count; Cell Cycle; Cell Division; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Iloprost; Mice; Polymerase Chain Reaction; Prostaglandins; Protein Binding; Receptors, Prostaglandin | 1996 |
Prostaglandin E2 both stimulates and inhibits adenyl cyclase on platelets: comparison of effects on cloned EP4 and EP3 prostaglandin receptor subtypes.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Blood Platelets; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Humans; Iloprost; Platelet Aggregation Inhibitors; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype | 1996 |
Role of potassium channels and nitric oxide in the effects of iloprost and prostaglandin E1 on hypoxic vasoconstriction in the isolated perfused lung of the rat.
Topics: Adenosine; Alprostadil; Animals; Colforsin; Enzyme Inhibitors; Hypoxia; Iloprost; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium Channels; Pulmonary Circulation; Rats; Rats, Wistar; Vasoconstriction; Vasodilator Agents | 1997 |
Activation of protein kinase C enhances the infection of endothelial cells by human cytomegalovirus.
Topics: Calcimycin; Cells, Cultured; Colforsin; Cytomegalovirus; Endothelium, Vascular; Enzyme Activation; Humans; Iloprost; Okadaic Acid; Protein Kinase C; Serotonin; Signal Transduction; Tetradecanoylphorbol Acetate; Umbilical Veins | 1997 |
Expression of prostacyclin receptor in human megakaryocytes.
Topics: Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Gene Expression Regulation; Gene Expression Regulation, Leukemic; Granulocyte-Macrophage Colony-Stimulating Factor; Hematologic Neoplasms; Hematopoietic Stem Cells; HL-60 Cells; Humans; Iloprost; Interleukins; Leukemia, Megakaryoblastic, Acute; Megakaryocytes; Neoplasm Proteins; Platelet Factor 4; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Epoprostenol; Receptors, Prostaglandin; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Thrombopoietin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
[Decrease of vascular response to iloprost in diabetic rats].
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Aorta, Thoracic; Colforsin; Coronary Vessels; Cromakalim; Diabetes Mellitus, Experimental; Iloprost; Potassium Channels; Rats; Rats, Sprague-Dawley; Streptozocin; Vascular Resistance; Vasodilation; Vasodilator Agents | 1997 |
Regulation of vascular endothelial growth factor expression by cAMP in rat aortic smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Aorta; Cobalt; Colforsin; Cyclic AMP; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Fibroblasts; Gene Expression Regulation; Iloprost; Isoproterenol; Lymphokines; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Rats; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Autocrine regulation of endothelial exocytosis: von Willebrand factor release is induced by prostacyclin in cultured endothelial cells.
Topics: Adenosine; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascular; Epoprostenol; Exocytosis; Humans; Iloprost; Molsidomine; Nitric Oxide; Nitroprusside; Thrombin; von Willebrand Factor | 1998 |
Elevation of cyclic AMP by iloprost and prostaglandin E1 increases cholesterol efflux and the binding capacity for high-density lipoproteins in human fibroblasts.
Topics: Alprostadil; Binding Sites; Biological Transport, Active; Cells, Cultured; Cholesterol; Colforsin; Cyclic AMP; Dinoprost; Fibroblasts; Humans; Iloprost; Kinetics; Lipoproteins, HDL; Lipoproteins, HDL3 | 1998 |
Evidence that adenosine diphosphate can activate adenylate cyclase via conversion to adenosine in platelet-rich plasma containing magnesium.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Colforsin; Cyclic AMP; Enzyme Activation; Humans; Iloprost; Magnesium; Platelet Aggregation Inhibitors; Platelet Count; Quinazolines; Receptors, Purinergic P2; Reference Values | 1998 |
Chronic captopril administration decreases vasodilator responses in skeletal muscle arterioles.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Blood Pressure; Captopril; Cholera Toxin; Colforsin; Drug Administration Routes; Follow-Up Studies; Iloprost; Muscle, Skeletal; Nitroprusside; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents; Video Recording | 1999 |
Development and reversibility of altered skeletal muscle arteriolar structure and reactivity with high salt diet and reduced renal mass hypertension.
Topics: Acetylcholine; Adenosine; Animals; Arterioles; Calcium; Cholera Toxin; Colforsin; Diet, Sodium-Restricted; Iloprost; Male; Microcirculation; Muscle, Skeletal; Nitroprusside; Rats; Rats, Sprague-Dawley; Vasodilation; Venous Pressure | 1999 |
Regulation of prostacyclin and prostaglandin E(2) receptor mediated responses in adult rat dorsal root ganglion cells, in vitro.
Topics: Adenylyl Cyclases; Aging; Alprostadil; Animals; Antineoplastic Agents; Cell Count; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Down-Regulation; Enzyme Activation; Epoprostenol; Ganglia, Spinal; Iloprost; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, Epoprostenol; Receptors, Prostaglandin | 2001 |
Cyclic AMP raises intracellular Ca(2+) in human megakaryocytes independent of protein kinase A.
Topics: 1-Methyl-3-isobutylxanthine; Calcium; Calcium Channels; Cell Line; Chelating Agents; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Humans; Iloprost; Inositol 1,4,5-Trisphosphate Receptors; Megakaryocytes; Phosphodiesterase Inhibitors; Phosphorylation; rap1 GTP-Binding Proteins; Receptors, Cytoplasmic and Nuclear; Vasodilator Agents | 2002 |
cAMP inhibits cytokine-induced biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Biopterins; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Combinations; Endothelium, Vascular; Enzyme Inhibitors; GTP Cyclohydrolase; Humans; Iloprost; Infant, Newborn; Interferon-gamma; RNA, Messenger; Tumor Necrosis Factor-alpha; Umbilical Veins | 2002 |
High-salt diet impairs vascular relaxation mechanisms in rat middle cerebral arteries.
Topics: Angiotensin II; Animals; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gs; Iloprost; Male; Middle Cerebral Artery; Muscle, Smooth, Vascular; Oxygen; Picolines; Prostaglandins F; Pyrans; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Thromboxane B2; Vasodilation; Vasodilator Agents | 2003 |
Induction of hyaluronic acid synthase 2 (HAS2) in human vascular smooth muscle cells by vasodilatory prostaglandins.
Topics: 6-Ketoprostaglandin F1 alpha; Acetophenones; Alprostadil; Arteriosclerosis; Becaplermin; Benzopyrans; Bucladesine; Carotid Artery Diseases; Carotid Artery, Internal; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Enzyme Induction; Epoprostenol; Extracellular Matrix; Glucuronosyltransferase; Humans; Hyaluronan Synthases; Hyaluronic Acid; Iloprost; Indoles; Isoenzymes; Isoquinolines; Macrophages; Maleimides; Membrane Proteins; Muscle Cells; Muscle, Smooth, Vascular; Pertussis Toxin; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-sis; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; RNA, Small Interfering; Sulfonamides; Vasodilator Agents | 2004 |
Prostacyclin induces apoptosis of vascular smooth muscle cells by a cAMP-mediated inhibition of extracellular signal-regulated kinase activity and can counteract the mitogenic activity of endothelin-1 or basic fibroblast growth factor.
Topics: Alprostadil; Animals; Apoptosis; Butadienes; Caspase 3; Caspases; Cell Division; Colforsin; Endothelin-1; Enzyme Activation; Epoprostenol; Fibroblast Growth Factor 2; Iloprost; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Microscopy, Confocal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitriles; Phosphorylation; Protein Processing, Post-Translational; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype | 2004 |
NO inhibits signal transduction pathway for ATP release from erythrocytes via its action on heterotrimeric G protein Gi.
Topics: Adenosine Triphosphate; Animals; Colforsin; Cyclic AMP; Erythrocytes; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Heterotrimeric GTP-Binding Proteins; Iloprost; Intercellular Signaling Peptides and Proteins; Male; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxygen; Partial Pressure; Peptides; Pertussis Toxin; Rabbits; Signal Transduction; Spermine; Wasp Venoms | 2004 |
Regulation of thrombomodulin expression in human vascular smooth muscle cells by COX-2-derived prostaglandins.
Topics: Alprostadil; Blood Coagulation; Bucladesine; Carotid Artery Diseases; Carotid Artery, Internal; Cells, Cultured; Colforsin; Coronary Vessels; Culture Media, Serum-Free; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Epoprostenol; Etoricoxib; Gene Expression Profiling; Gene Expression Regulation; Humans; Iloprost; Isoquinolines; Mammary Arteries; Membrane Proteins; Models, Biological; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyridines; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; RNA, Messenger; Saphenous Vein; Second Messenger Systems; Sulfonamides; Sulfones; Tetradecanoylphorbol Acetate; Thrombomodulin; Thrombophilia; Vasodilator Agents | 2005 |
Iloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Animals; Cell Culture Techniques; Colforsin; Cyclic AMP; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Female; Hypertension, Pulmonary; Iloprost; Infusions, Parenteral; Lung; Male; Myocytes, Smooth Muscle; Rabbits; Receptors, Epoprostenol; Vasodilator Agents | 2007 |
IL-1beta, BK, and TGF-beta1 attenuate PGI2-mediated cAMP formation in human pulmonary artery smooth muscle cells by multiple mechanisms involving p38 MAP kinase and PKA.
Topics: Adult; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Epoprostenol; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Iloprost; Interleukin-1beta; Male; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Transforming Growth Factor beta1 | 2008 |
Regulation of cytokine expression in human plasmacytoid dendritic cells by prostaglandin I2 analogues.
Topics: Benzophenones; Colforsin; Cyclic AMP; Cytokines; Dendritic Cells; Enzyme-Linked Immunosorbent Assay; Epoprostenol; Gene Expression Regulation; Humans; Iloprost; Imidazoles; Interferon-alpha; Interleukin-10; Oligonucleotides; Platelet Aggregation Inhibitors; Signal Transduction; Tumor Necrosis Factor-alpha | 2009 |
Inhibition of ATP release from erythrocytes: a role for EPACs and PKC.
Topics: Adenine; Adenosine Triphosphate; Cilostazol; Colforsin; Cyclic AMP; Enzyme Activation; Erythrocytes; Guanine Nucleotide Exchange Factors; Humans; Iloprost; In Vitro Techniques; Isoproterenol; Models, Biological; Naphthalenes; Phosphodiesterase Inhibitors; Protein Kinase C; Rolipram; Signal Transduction; Tetradecanoylphorbol Acetate; Tetrazoles; Thionucleotides | 2011 |
Modafinil inhibits K(Ca)3.1 currents and muscle contraction via a cAMP-dependent mechanism.
Topics: Animals; Benzhydryl Compounds; Carrier Proteins; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Humans; Iloprost; Intermediate-Conductance Calcium-Activated Potassium Channels; Isoquinolines; Male; Membrane Potentials; Mice; Modafinil; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NIH 3T3 Cells; Patch-Clamp Techniques; Peptide Fragments; Phosphorylation; Potassium Channel Blockers; Protein Kinase Inhibitors; Rats; Second Messenger Systems; Sulfonamides; Time Factors; Up-Regulation; Vasoconstriction; Vasodilator Agents | 2012 |
Attenuation of inhibitory prostaglandin E2 signaling in human lung fibroblasts is mediated by phosphodiesterase 4.
Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Aminopyridines; Benzamides; Cells, Cultured; Chemotaxis; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Dinoprostone; Fibroblasts; Fibronectins; Gene Expression; Humans; Iloprost; Isoenzymes; Lung; Phosphodiesterase 4 Inhibitors; Pulmonary Disease, Chronic Obstructive; Receptors, Epoprostenol; Receptors, Prostaglandin; Receptors, Prostaglandin E, EP2 Subtype; Rolipram; Second Messenger Systems | 2012 |
Iloprost up-regulates vascular endothelial growth factor expression in human dental pulp cells in vitro and enhances pulpal blood flow in vivo.
Topics: Adolescent; Adult; Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dental Pulp; Dental Pulp Exposure; Disease Models, Animal; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Humans; Iloprost; Molar; Neovascularization, Physiologic; Platelet-Derived Growth Factor; Rats; Receptors, Fibroblast Growth Factor; Regional Blood Flow; Vascular Endothelial Growth Factor A; Young Adult | 2014 |