colforsin and h 89

Topics: Colforsin; HeLa Cells; Humans; Isoquinolines; Kinetics; Phosphatidylcholines; Protein Kinase Inhibitors; Sulfonamides; Tetradecanoylphorbol Acetate

Topics: Adrenal Gland Neoplasms; Animals; Axons; Bucladesine; Cell Line; Colforsin; Isoquinolines; Kinetics; Neoplasm Proteins; Nerve Growth Factors; Pheochromocytoma; Phosphorylation; Protein Kinase Inhibitors; Sulfonamides

Topics: Animals; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoquinolines; Melanoma, Experimental; Melatonin; Mice; Protein Biosynthesis; Proteins; Sulfonamides; Tumor Cells, Cultured

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Base Sequence; Binding Sites; Blotting, Northern; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Gene Expression; Isoquinolines; Kinetics; Molecular Sequence Data; Naphthalenes; Nerve Growth Factors; Neuropeptide Y; Oligodeoxyribonucleotides; PC12 Cells; Piperazines; Polycyclic Compounds; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic

Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Brain; Brain Neoplasms; Cloning, Molecular; Colforsin; Creatine Kinase; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Energy Metabolism; Enzyme Activation; Enzyme Induction; Glioblastoma; Glioma; HeLa Cells; Humans; Isoenzymes; Isoquinolines; Myelin Sheath; Nerve Tissue Proteins; Neuroglia; Protein Synthesis Inhibitors; Rats; Recombinant Fusion Proteins; RNA, Antisense; Sulfonamides; Transcription, Genetic; Transfection; Tumor Cells, Cultured

Topics: 1-Methyl-3-isobutylxanthine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine Agonists; Ergolines; Goldfish; Growth Hormone; In Vitro Techniques; Indicators and Reagents; Isoquinolines; Pituitary Gland; Quinpirole; Receptors, Dopamine D1; Sulfonamides

Topics: Adenylyl Cyclases; Adrenal Gland Neoplasms; Animals; Chloramphenicol O-Acetyltransferase; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Gene Expression; Isoquinolines; Kinetics; Naphthalenes; Neuropeptide Y; PC12 Cells; Pheochromocytoma; Polycyclic Compounds; Promoter Regions, Genetic; Protein Kinase C; Rats; Sulfonamides; Transcription, Genetic

Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arginine Vasopressin; Bradykinin; Calcimycin; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diglycerides; Dogs; Enzyme Activation; Enzyme Inhibitors; Estrenes; Inositol Phosphates; Ionophores; Isoquinolines; Kidney; Pyrrolidinones; Sulfonamides; Type C Phospholipases

Topics: Animals; Bone Neoplasms; Cell Line; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Enzyme Inhibitors; Humans; Isoquinolines; Kinetics; Osteosarcoma; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Protein Kinase C; Proteins; Rats; Recombinant Proteins; Second Messenger Systems; Sodium-Hydrogen Exchangers; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Aorta; Binding, Competitive; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Isoquinolines; Isotope Labeling; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Rubidium; Sulfonamides; Vasodilator Agents

Topics: Adrenal Cortex; Animals; Calcium; Cattle; Chromaffin Granules; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Isoquinolines; Nicotine; Phosphorylation; Protein Kinase Inhibitors; Receptors, Nicotinic; Sulfonamides; Tyrosine 3-Monooxygenase

Topics: Animals; Antiporters; Bicarbonates; Bile; Bucladesine; Cells, Cultured; Chloride-Bicarbonate Antiporters; Chlorides; Cholagogues and Choleretics; Colchicine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glucagon; Hydrogen-Ion Concentration; Intracellular Fluid; Isoquinolines; Liver; Male; Nitrobenzoates; Rats; Rats, Wistar; Sodium; Sodium-Hydrogen Exchangers; Sulfonamides; Tetradecanoylphorbol Acetate; Thionucleotides

Topics: Animals; Bucladesine; Calcium; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Isoquinolines; Male; Membrane Potentials; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Sulfonamides

Topics: Animals; Barium; Calcium Channels; Cell Line; Colforsin; Electric Conductivity; Embryo, Mammalian; Ferrets; Heart; Humans; Isoquinolines; Kidney; Kinetics; Protein Kinase Inhibitors; Sulfonamides

Topics: Amino Acid Sequence; Animals; Arginine Vasopressin; Binding Sites; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Endothelins; GTP-Binding Proteins; In Vitro Techniques; Isoquinolines; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Receptors, Endothelin; Stereoisomerism; Sulfonamides

Topics: Animals; Calcium; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Indoles; Isoquinolines; Long-Term Potentiation; Models, Biological; Nerve Fibers; Presynaptic Terminals; Pyramidal Cells; Pyrroles; Sulfonamides; Synaptic Transmission

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Dopamine; Female; Goldfish; Gonadotropin-Releasing Hormone; Growth Hormone; Isoquinolines; Male; Piperazines; Pituitary Gland; Protein Kinase C; Sulfonamides; Verapamil

Topics: Absorption; Animals; Atrial Natriuretic Factor; Calcitonin; Calcitriol; Calcium; Cattle; Cells, Cultured; Colforsin; Culture Media; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Epithelium; Flounder; Glycoproteins; Growth Hormone; Hormones; Isoquinolines; Kidney Tubules, Proximal; Kinetics; Membrane Potentials; Parathyroid Hormone; Phosphates; Prolactin; Protein Kinase Inhibitors; Sulfonamides; Time Factors; Triiodothyronine

Topics: Animals; Arteries; Colforsin; Cyclic AMP; Cyclic GMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Activation; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; Muscle, Smooth, Vascular; Norepinephrine; Protein Kinase C; Rats; Rats, Wistar; Regional Blood Flow; Sulfonamides; Synaptic Transmission; Tail; Vasoconstriction

Topics: Animals; Cerebellum; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoquinolines; Male; N-Methylaspartate; Nitric Oxide; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sulfonamides

Topics: Animals; Barium; Calcium; Calcium Channels; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Humans; Isoquinolines; Membrane Potentials; Myocardium; Phosphorylation; Rabbits; Rats; Sulfonamides; Transfection

Topics: Cell Membrane; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytosol; Diglycerides; HeLa Cells; Humans; Isoquinolines; Nucleotidyltransferases; Phosphatidylcholines; Phosphorylation; Protein Kinase C; Sulfonamides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Base Sequence; Bucladesine; Cholera Toxin; Colforsin; Consensus Sequence; Cyclic AMP; Dinoprostone; Female; Gene Expression Regulation, Neoplastic; Isoquinolines; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neoplasm Proteins; NF-kappa B; Phosphorylation; Piperazines; Protein Kinases; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription Factor RelB; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured

Topics: Alprostadil; Apoptosis; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Enzyme Inhibitors; Humans; Isoquinolines; Neutrophils; Prostaglandins E, Synthetic; Receptors, IgG; Sulfonamides

Topics: Adenylyl Cyclases; Butyrates; Butyric Acid; Cell Division; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Cyclins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Isoquinolines; Neoplasm Invasiveness; Oncogene Proteins; Oncogenes; Ovarian Neoplasms; Protein Kinase C; Proteins; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Antibodies, Anti-Idiotypic; Antigens, CD; B-Lymphocytes; B7-2 Antigen; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Immunoglobulins; Ionomycin; Isoquinolines; Lymphoma, B-Cell; Membrane Glycoproteins; Mice; Molecular Sequence Data; Phosphorylation; Piperazines; Protein Kinase C; Rats; Receptors, Antigen, B-Cell; Signal Transduction; Staurosporine; Sulfonamides

Topics: 3-O-Methylglucose; Amino Acid Sequence; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Glucagon-Like Peptide 1; Glucose Transporter Type 2; Isoquinolines; Kinetics; Methylglucosides; Molecular Sequence Data; Monosaccharide Transport Proteins; Peptides; Phosphorylation; Rats; Sulfonamides; Tumor Cells, Cultured

Topics: Animals; Base Sequence; Bone and Bones; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Female; Gene Expression Regulation; Insulin-Like Growth Factor Binding Protein 5; Isoquinolines; Molecular Sequence Data; Osteoblasts; Pregnancy; Promoter Regions, Genetic; Protein Kinase C; Rats; RNA, Heterogeneous Nuclear; RNA, Messenger; Sulfonamides; Transcription, Genetic

Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Colforsin; Cyclic AMP; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glucose; Hexokinase; Hexoses; Isoquinolines; Liver Neoplasms, Experimental; Mannoheptulose; Promoter Regions, Genetic; Rats; Signal Transduction; Sulfonamides; Transfection; Tumor Cells, Cultured

Topics: Adrenocorticotropic Hormone; Animals; Bucladesine; Calcimycin; Cattle; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Hydrocortisone; Immunohistochemistry; Isoquinolines; Kinetics; Naphthalenes; Phosphoproteins; Quinazolines; Sulfonamides; Tetradecanoylphorbol Acetate; Zona Fasciculata

Topics: Adenosine Triphosphate; Animals; Binding Sites; Calcimycin; Calcium; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Humans; Imidazoles; Isoquinolines; Kinetics; Levamisole; Membrane Potentials; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Point Mutation; Recombinant Proteins; Sulfonamides; Tetramisole; Thiazoles; Transfection

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cycloheximide; Ethers, Cyclic; Isoquinolines; Mice; Nicotine; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Receptors, Cholinergic; Sulfonamides

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adrenal Medulla; Animals; Calcium; Catecholamines; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Inhibitors; Isoquinolines; Membrane Potentials; Ouabain; Protein Kinase Inhibitors; Receptors, Cholinergic; Sodium; Sodium-Potassium-Exchanging ATPase; Sulfonamides; Tetrodotoxin; Thionucleotides

Topics: Adenine; Aluminum Compounds; Animals; Bucladesine; Calcium; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diterpenes; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Fluorides; GTP-Binding Proteins; Isoquinolines; Male; Muscle, Smooth; PC12 Cells; Rats; Serotonin; Serotonin Antagonists; Sulfonamides; Trachea

Topics: 3T3 Cells; Animals; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Synergism; Genistein; Isoflavones; Isoquinolines; Marine Toxins; Mice; Oxazoles; Phosphoprotein Phosphatases; Protein Kinase Inhibitors; Sulfonamides; Transfection

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbazoles; Chickens; Cochlea; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA Replication; Enzyme Activation; Enzyme Inhibitors; Gentamicins; Hair Cells, Auditory; Hearing Loss, Sensorineural; Indoles; Isoquinolines; Organ Culture Techniques; Pyrroles; Regeneration; Signal Transduction; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Cell Compartmentation; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endoplasmic Reticulum; Enzyme Inhibitors; Exocytosis; Golgi Apparatus; Hexosaminidases; Isoquinolines; Membrane Glycoproteins; Microscopy, Electron; Protein Processing, Post-Translational; Rats; Sulfonamides; Viral Envelope Proteins

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Cell Nucleus; Cells, Cultured; Cloning, Molecular; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Enzyme Inhibitors; Heart; Isoquinolines; Kinetics; Myocardium; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Recombinant Proteins; RNA, Messenger; Sulfonamides; Transcription, Genetic

Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Becaplermin; Benzazepines; Cells, Cultured; Colforsin; Dopamine Antagonists; Hypertrophy; Isoquinolines; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Rats; Receptors, Dopamine D1; Renal Artery; Sulfonamides; Tetrahydroisoquinolines

Topics: Alprostadil; Animals; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Interleukin-6; Isoquinolines; Mice; Osteoblasts; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cardiomegaly; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gene Expression; Genes, fos; Glucagon; Isoquinolines; Male; Perfusion; Phosphodiesterase Inhibitors; Pressure; Protein Biosynthesis; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sulfonamides

Topics: Alprostadil; Animals; Cell Line; Colforsin; Collagenases; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Interleukin-1; Isoenzymes; Isoquinolines; Matrix Metalloproteinase 1; Protein Kinase C; Protein Kinase C-alpha; Rabbits; RNA, Messenger; Sulfonamides; Synovial Membrane; Thionucleotides; Transfection

Topics: Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Isoquinolines; Mice; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Neoplasms; Polymerase Chain Reaction; Pro-Opiomelanocortin; Rats; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone; Receptors, Vasoactive Intestinal Peptide; Sulfonamides; Tumor Cells, Cultured; Vasoactive Intestinal Peptide

Topics: 1-Methyl-3-isobutylxanthine; Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Female; Indoles; Isoquinolines; Maleimides; Meiosis; Oocytes; Phorbol Esters; Protein Kinase C; Signal Transduction; Sulfonamides; Time Factors

Topics: Blotting, Northern; Breast Neoplasms; Calcitonin; Carcinogens; Cell Division; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Epidermal Growth Factor; Female; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Glycoproteins; Humans; Insulin; Isoquinolines; Metalloendopeptidases; Protein Biosynthesis; Protein Kinase Inhibitors; Proteins; Receptors, Calcitonin; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases; Tumor Cells, Cultured

Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cattle; Cell Communication; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; In Vitro Techniques; Isoquinolines; Meiosis; Oocytes; Oogenesis; Phosphodiesterase Inhibitors; Signal Transduction; Sulfonamides; Theca Cells

Topics: Adenylyl Cyclases; Animals; Catecholamines; Cattle; Chromaffin Cells; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Isoquinolines; Phenylethanolamine N-Methyltransferase; RNA, Messenger; Sulfonamides; Tyrosine 3-Monooxygenase

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenylyl Cyclase Inhibitors; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Electric Stimulation; Embryo, Mammalian; Enzyme Inhibitors; gamma-Aminobutyric Acid; Hypothalamus, Middle; Isoquinolines; Neurons; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides; Synapses; Tetrodotoxin; Thionucleotides

Topics: Adrenergic beta-Agonists; Animals; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Female; Genistein; Guinea Pigs; Heart Ventricles; Isoflavones; Isoproterenol; Isoquinolines; Male; Marine Toxins; Myocardium; Oxazoles; Patch-Clamp Techniques; Protein-Tyrosine Kinases; Sulfonamides

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adrenal Gland Neoplasms; Animals; Blotting, Western; Caffeine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Enzyme Activation; Enzyme Inhibitors; Isoquinolines; Kinetics; PC12 Cells; Phenethylamines; Pheochromocytoma; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Recombinant Proteins; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Alanine; Animals; Cell Line; Colforsin; COS Cells; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoproterenol; Isoquinolines; Macromolecular Substances; Mutagenesis, Site-Directed; Okadaic Acid; Phosphorylation; Point Mutation; Rats; Recombinant Proteins; Rubidium; Serine; Sodium-Potassium-Exchanging ATPase; Spodoptera; Sulfonamides; Transfection

Topics: Adenylyl Cyclases; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Insulinoma; Islets of Langerhans; Isoquinolines; Kinetics; Microtubule-Associated Proteins; Pancreatic Neoplasms; Peptide Mapping; Phosphopeptides; Phosphorylation; Rats; Sulfonamides; Tumor Cells, Cultured

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Capillaries; Cattle; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Fibroblast Growth Factor 2; Isoproterenol; Isoquinolines; Lymphokines; Phosphodiesterase Inhibitors; Proto-Oncogene Proteins c-raf; Signal Transduction; Sulfonamides; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Clone Cells; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kinetics; Neuropeptides; Neurotransmitter Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland, Anterior; Signal Transduction; Sulfonamides; Time Factors; Type C Phospholipases; Vasoactive Intestinal Peptide

Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Becaplermin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Agonists; Dopamine Antagonists; Enzyme Activation; Enzyme Inhibitors; Growth Inhibitors; Isoquinolines; Muscle, Smooth, Vascular; Naphthalenes; Phospholipase D; Platelet-Derived Growth Factor; Protein Kinase C; Proto-Oncogene Proteins c-sis; Rats; Rats, Wistar; Receptors, Dopamine D1; Renal Artery; Signal Transduction; Sulfonamides; Tetrahydroisoquinolines

Topics: Acetylcholine; Adenylyl Cyclases; Animals; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Genistein; Guinea Pigs; Isoquinolines; Myocardium; Patch-Clamp Techniques; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Sulfonamides; Vanadates

Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Enzyme Inhibitors; Estrenes; Female; Isoquinolines; Meiosis; Oocytes; Oogenesis; Phosphatidylinositols; Progesterone; Protein Kinase Inhibitors; Pyrrolidinones; Receptors, Serotonin; RNA, Messenger; Signal Transduction; Sulfonamides; Time Factors; Type C Phospholipases; Xenopus laevis

Topics: 1-Methyl-3-isobutylxanthine; Biological Transport; Bucladesine; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; Genistein; Humans; Isoquinolines; Kidney Tubules, Proximal; Kinetics; Nitriles; Protein Kinase C; Protein-Tyrosine Kinases; Riboflavin; Sulfonamides; Temperature; Tyrphostins

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; DNA-Binding Proteins; Drug Synergism; Enzyme Inhibitors; Genes, Reporter; Hydroxycholesterols; Indoles; Isoquinolines; Liver X Receptors; Maleimides; Orphan Nuclear Receptors; Protein Kinase C; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection

Topics: Action Potentials; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Hot Temperature; Hyperalgesia; Isoquinolines; Neurons, Afferent; Nociceptors; Rana pipiens; Skin; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Ambystoma; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Glycine Agents; Isoquinolines; Kinetics; Kynurenic Acid; Membrane Potentials; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Protein Kinase C; Retinal Ganglion Cells; Strychnine; Sulfonamides

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenoleukodystrophy; Animals; Astrocytes; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytokines; Enzyme Inhibitors; Fatty Acids; Genetic Linkage; Interleukin-1; Isoquinolines; Neuroglia; Oxidation-Reduction; Protein Kinase Inhibitors; Pyrrolidinones; Rats; Rolipram; Sulfonamides; Tumor Necrosis Factor-alpha; X Chromosome

Topics: Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Colforsin; Enzyme Inhibitors; Glyburide; Guanidines; Isoquinolines; Membrane Potentials; Osteoblasts; Osteosarcoma; Pinacidil; Potassium; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Rats; Sulfonamides; Tetraethylammonium; Tumor Cells, Cultured

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Antagonists; Animals; Aorta; Calcimycin; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelium, Vascular; Enhancer Elements, Genetic; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Isoproterenol; Isoquinolines; Kinetics; Luciferases; Rabbits; Signal Transduction; Sulfonamides; Transfection

Topics: Adenosine Monophosphate; Animals; Base Sequence; Cell Differentiation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Estradiol; Female; Follicle Stimulating Hormone; Granulosa Cells; Isoquinolines; Luteinizing Hormone; Molecular Sequence Data; Ovulation; Polyunsaturated Alkamides; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Sulfonamides

Topics: 3T3 Cells; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprost; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate; Iodides; Isoquinolines; Kinetics; Mice; Phosphopeptides; Phosphorylation; Protein Kinase C; Recombinant Proteins; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection

Topics: Animals; Bucladesine; Calcium; Cells, Cultured; Cilia; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Enzyme Inhibitors; Esophagus; Estrenes; Homeostasis; Isoquinolines; Kinetics; Mucous Membrane; Pyrrolidinones; Rana ridibunda; Sulfonamides; Thapsigargin; Type C Phospholipases

Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Colforsin; Cyclic GMP; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; Guinea Pigs; Isoproterenol; Isoquinolines; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitric Oxide; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Receptors, Adrenergic, beta; Sulfonamides

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine; Cerebellum; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; In Vitro Techniques; Isoquinolines; Long-Term Potentiation; Male; Nitric Oxide; Rats; Rats, Wistar; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Pressure; Cardiomegaly; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression; Glucagon; HSP70 Heat-Shock Proteins; Hypertension; In Vitro Techniques; Isoquinolines; Male; Myocardium; Naphthalenes; Perfusion; Protein Biosynthesis; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Sulfonamides

Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Action Potentials; Adenylate Cyclase Toxin; Adjuvants, Immunologic; Adrenergic beta-Agonists; Animals; Cholera Toxin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Isoproterenol; Isoquinolines; Kinetics; Male; Mice; Muscarinic Agonists; Naphthalenes; Oxotremorine; Protein Kinase C; Receptors, Adrenergic, beta; Sulfonamides; Virulence Factors, Bordetella

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biological Transport; Carrier Proteins; Colforsin; Corpus Striatum; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Enzyme Activation; Enzyme Inhibitors; Isoquinolines; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Quinpirole; Rats; Rats, Sprague-Dawley; Sulfonamides; Sulpiride; Up-Regulation

Topics: Adenosine; Adenosine Triphosphate; Alkynes; Animals; Bucladesine; Calcimycin; Calcium; Carbachol; Cholinergic Agonists; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Ionophores; Isoquinolines; Membrane Potentials; Norepinephrine; PC12 Cells; Potassium Chloride; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A2A; Sulfonamides; Thionucleotides; Tritium; Vasodilator Agents

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; DNA Replication; Enzyme Inhibitors; Flavonoids; Isoquinolines; Mice; Pituitary Gland, Anterior; Pituitary Neoplasms; Sheep; Sulfonamides; Thymidine

Topics: Animals; Cell Line; Colforsin; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Isoquinolines; Phosphorylation; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone; Receptors, Vasoactive Intestinal Peptide; Receptors, Vasoactive Intestinal Peptide, Type II; Recombinant Proteins; Sulfonamides; Transfection; Vasoactive Intestinal Peptide

Topics: 1-Methyl-3-isobutylxanthine; Animals; Biotinylation; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Humans; Isoquinolines; Microscopy, Fluorescence; Receptors, G-Protein-Coupled; Receptors, Gastrointestinal Hormone; Secretin; Signal Transduction; Sulfonamides; Transfection

Topics: Alkaloids; Animals; Benzophenanthridines; Biological Transport; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Fetus; Glutamic Acid; Isoquinolines; Kinetics; Neurons; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cerebellum; Colforsin; Cyclic AMP; Electric Stimulation; Enzyme Inhibitors; Evoked Potentials; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Isoquinolines; Long-Term Potentiation; Methiothepin; Neuronal Plasticity; Norepinephrine; Propranolol; Protein Kinase Inhibitors; Purkinje Cells; Rats; Rats, Wistar; Receptors, GABA; Serotonin; Sulfonamides; Synapses; Synaptic Transmission; Tetrodotoxin; Thionucleotides

Topics: Animals; Carcinogens; Cell Division; Cells, Cultured; Colforsin; Dexamethasone; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Feedback; Flow Cytometry; Glucocorticoids; Granulocytes; Interleukin-1; Interleukin-2; Interleukin-6; Isoquinolines; Lymph Nodes; Macrophages, Peritoneal; Male; Mast Cells; Mitogens; Neuroimmunomodulation; Peritoneum; Rats; Rats, Wistar; Retinaldehyde; Sensitivity and Specificity; Spleen; Sulfonamides; Tetradecanoylphorbol Acetate; Thymus Gland; Tumor Necrosis Factor-alpha; Vasoactive Intestinal Peptide

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cesium; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dihydropyridines; Drosophila; Enzyme Inhibitors; Isoquinolines; Larva; Membrane Potentials; Muscles; Mutagenesis; Nervous System; Phosphodiesterase Inhibitors; Sulfonamides

Topics: Animals; Anions; Chelating Agents; Colforsin; Culture Techniques; Cyclic AMP; Egtazic Acid; Enzyme Inhibitors; Epididymis; Epithelium; Imines; Isoquinolines; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin; Sulfonamides; Thapsigargin

Topics: Acetylcholine; Age Factors; Animals; Animals, Newborn; Bucladesine; Calcium; Calcium Signaling; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Inositol 1,4,5-Trisphosphate; Isoquinolines; Male; Rats; Rats, Sprague-Dawley; Submandibular Gland; Sulfonamides; Thapsigargin

Topics: 1-Methyl-3-isobutylxanthine; Breast Neoplasms; Cell Cycle Proteins; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Female; Humans; Isoquinolines; Kinetics; Lovastatin; Microtubule-Associated Proteins; Protein Processing, Post-Translational; Sulfonamides; Transfection; Tumor Cells, Cultured; Tumor Suppressor Proteins

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dactinomycin; Enzyme Inhibitors; Humans; Isoquinolines; Nerve Tissue Proteins; Neuregulin-1; Neurotrophin 3; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Schwann Cells; Sulfonamides; Transforming Growth Factor beta

Topics: Animals; Arylamine N-Acetyltransferase; Chick Embryo; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Drug Synergism; Enzyme Inhibitors; Isoquinolines; Photoreceptor Cells; Protein Synthesis Inhibitors; Retina; RNA, Messenger; Sulfonamides

Topics: Adrenomedullin; Animals; Bucladesine; Calcitonin Gene-Related Peptide; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; Humans; Isoquinolines; Membrane Proteins; Peptide Fragments; Peptides; Pressure; Rats; Receptors, Adrenomedullin; Receptors, Peptide; Sulfonamides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Animals; Calcium Channel Blockers; Calmodulin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Glioma; Imidazoles; Isoquinolines; Nimodipine; Proto-Oncogene Proteins c-jun; Rats; RNA, Messenger; Sulfonamides; Tumor Cells, Cultured

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenomedullin; Angiotensin II; Animals; Becaplermin; Calcitonin Gene-Related Peptide; Cell Adhesion; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epoprostenol; Glomerular Mesangium; Humans; Isoquinolines; Peptide Fragments; Peptides; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Sulfonamides

Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Cardiovascular Agents; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Isoquinolines; Male; Membrane Potentials; Morphine; N-Methylaspartate; Neural Inhibition; Periaqueductal Gray; Phenylephrine; Pyrimidines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Substance Withdrawal Syndrome; Sulfonamides; Sympathomimetics; Tetrazoles; Tetrodotoxin; Thionucleotides

Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Arginase; Caco-2 Cells; Colforsin; Cyclic AMP; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Isoquinolines; Kinetics; Okadaic Acid; Protein Biosynthesis; RNA, Messenger; Sulfonamides; Transcription, Genetic

Topics: Adenylyl Cyclases; Animals; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide-Gated Cation Channels; Dopamine; Electrophysiology; Enzyme Inhibitors; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Ion Channels; Isoquinolines; Mice; Neurons; Patch-Clamp Techniques; Signal Transduction; Sulfonamides

Topics: Adenylyl Cyclases; Animals; Biological Transport; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Electric Conductivity; Electrophysiology; Enzyme Activation; Enzyme Inhibitors; Guinea Pigs; Heart Ventricles; Isoquinolines; Myocardium; Sodium; Sodium-Potassium-Exchanging ATPase; Sulfonamides

Topics: 1-Propanol; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Barium; Calcium Channels, L-Type; Cells, Cultured; Cholera Toxin; Colforsin; Dose-Response Relationship, Drug; Electric Stimulation; Isoproterenol; Isoquinolines; Membrane Potentials; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Portal Vein; Propanolamines; Rats; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Isoquinolines; Leukemia; NF-kappa B; Sulfonamides; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

Topics: Acrosome; Acrosome Reaction; Analysis of Variance; Animals; Aristolochic Acids; Bucladesine; Caffeine; Calcimycin; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Inhibitors; Ionophores; Isoquinolines; Lysophosphatidylcholines; Male; Phenanthrenes; Phospholipases A; Phospholipases A2; Protein Kinase Inhibitors; Sheep; Stimulation, Chemical; Sulfonamides

Topics: Animals; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation; Interleukin-1; Interleukin-6; Isoquinolines; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Oligonucleotides, Antisense; Prostaglandins; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Sulfonamides; Transcription Factor AP-1; Transcription, Genetic

Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression; Isoquinolines; Lipopolysaccharides; Microglia; Neurons; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone; Receptors, Vasoactive Intestinal Peptide; Receptors, Vasoactive Intestinal Polypeptide, Type I; RNA, Messenger; Signal Transduction; Spinal Cord Injuries; Sulfonamides; Tumor Necrosis Factor-alpha; Vasoactive Intestinal Peptide

Topics: B-Lymphocytes; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression Regulation; Humans; Interleukin-4; Isoquinolines; Kinetics; Palatine Tonsil; Receptors, Interleukin-2; Receptors, Interleukin-4; Signal Transduction; Sulfonamides

Topics: Adenine; Adenylyl Cyclase Inhibitors; Amidines; Animals; Arginine; Benzylamines; Carbazoles; Colforsin; Cyclic AMP; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Fundus; In Vitro Techniques; Indoles; Isoquinolines; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Oxadiazoles; Protein Kinase Inhibitors; Pyrroles; Quinoxalines; Sulfonamides; Swine; Thionucleotides; Vasoactive Intestinal Peptide

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Isoquinolines; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Protein Kinase C; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-raf; Rats; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate

Topics: Adrenergic beta-Agonists; Amino Acid Substitution; Animals; Binding Sites; Colforsin; COS Cells; Enzyme Activation; Enzyme Inhibitors; Glycogen; Glycogen Synthase; Isoproterenol; Isoquinolines; Muscle, Skeletal; Phosphoprotein Phosphatases; Protein Kinase Inhibitors; Protein Phosphatase 1; Rabbits; Signal Transduction; Structure-Activity Relationship; Sulfonamides

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Hypothalamus; Isoquinolines; Kinetics; Marine Toxins; N-Methylaspartate; Oocytes; Oxazoles; Phosphoprotein Phosphatases; Protein Kinase C; Protein Phosphatase 1; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; RNA, Messenger; Sulfonamides; Xenopus laevis

Topics: Animals; Apoptosis; Bucladesine; Calcitonin; Caspases; Cell Survival; Cells, Cultured; Coculture Techniques; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Interleukin-1; Isoquinolines; Male; Mice; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Osteoclasts; Rabbits; Signal Transduction; Sulfonamides

Topics: Alkaloids; Animals; Blood Platelets; Carbazoles; Cattle; Cell Adhesion Molecules; Colforsin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Glomerular Mesangium; Humans; Indoles; Isoquinolines; Microfilament Proteins; Nitric Oxide; Phosphoproteins; Phosphorylation; Rats; Sulfonamides

Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Division; Cell Line; Cell Survival; Chromones; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytosol; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Activation; Enzyme Inhibitors; Epithelium; Fibroblasts; Flavonoids; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Intestinal Mucosa; Isoquinolines; Microscopy, Fluorescence; Mitochondria; Morpholines; Peptides; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Receptors, Cell Surface; Receptors, Glucagon; Signal Transduction; Sulfonamides; Time Factors; Transfection

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adjuvants, Immunologic; Animals; Butadienes; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Inhibitors; Extracellular Space; Flavonoids; Gene Expression; Indoles; Isoquinolines; Maleimides; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neuropeptides; Nitriles; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Prolactin; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptor Cross-Talk; RNA, Messenger; Sulfonamides; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Calcium; Cell Size; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Fluorescent Dyes; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Isoquinolines; MAP Kinase Signaling System; Protein Kinase C; Receptors, Metabotropic Glutamate; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases

Topics: Animals; Calcium; Cholecystokinin; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Electrophoresis; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Reporter; Isoquinolines; Luciferases; Mice; Mutagenesis; Neuroendocrine Tumors; Neuropeptides; Oligonucleotide Probes; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Promoter Regions, Genetic; Rats; Sulfonamides; Transcription Factor AP-1; Transcription, Genetic; Tumor Cells, Cultured

Topics: Adrenomedullin; Animals; Antihypertensive Agents; Arginine Vasopressin; Blotting, Western; Calcium; Carcinogens; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; Isoquinolines; Male; Mitogen-Activated Protein Kinases; Peptides; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents

Topics: Adenylyl Cyclases; Animals; Bradykinin; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Ganglia, Spinal; Inositol 1,4,5-Trisphosphate; Isoquinolines; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Substance P; Sulfonamides; Tritium

Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiogenesis Inhibitors; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cell Survival; Clone Cells; Colforsin; Cyclic AMP; Endothelium, Vascular; Enzyme Activation; Fatty Acids, Unsaturated; Humans; Hydrazines; Isoquinolines; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Thromboxane; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sulfonamides; Thromboxane A2; Time Factors

Topics: Animals; Apoptosis; Brain Chemistry; Calcium-Calmodulin-Dependent Protein Kinases; Cell Fractionation; Cell Survival; Cells, Cultured; Cerebellum; Colforsin; Culture Media, Serum-Free; Cyclic AMP; Enzyme Inhibitors; Flavonoids; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Immunoblotting; Isoquinolines; Neurons; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Recombinant Fusion Proteins; Sulfonamides; Transfection

Topics: Animals; Bucladesine; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Protein-delta; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Isoquinolines; Luciferases; Male; Muscle, Smooth, Vascular; Oligonucleotides; Phospholipases A; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Transcription Factors; Transcription, Genetic; Transfection

Topics: Adenine; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclopentanes; Entorhinal Cortex; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; In Vitro Techniques; Indoles; Isoquinolines; Male; Maleimides; Presynaptic Terminals; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Sulfonamides; Tricarboxylic Acids

Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Colforsin; Enzyme Activation; Enzyme Inhibitors; Estrenes; Indoles; Isoquinolines; Kinetics; Maleimides; Models, Biological; Phospholipases A; Purine Nucleotides; Pyrimidine Nucleotides; Pyrrolidinones; Rana ridibunda; Receptor Cross-Talk; Receptors, Purinergic P2; Semicircular Canals; Sulfonamides; Suramin; Uridine Triphosphate

Topics: Adrenal Medulla; Animals; Biological Assay; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Colforsin; Cyclic AMP; Digitonin; Enzyme Inhibitors; Indicators and Reagents; Isoquinolines; Permeability; Phosphorylation; Solubility; Sulfonamides; Tyrosine 3-Monooxygenase

Topics: Active Transport, Cell Nucleus; alpha-MSH; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; DNA; Drug Interactions; Enzyme Inhibitors; Genes, Reporter; Interferon-gamma; Isoquinolines; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitrites; Peptides; Receptors, Corticotropin; Receptors, Melanocortin; Sulfonamides

Topics: beta-Adrenergic Receptor Kinases; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA, Antisense; Enzyme Inhibitors; Eye Neoplasms; G-Protein-Coupled Receptor Kinase 3; Gene Expression Regulation, Enzymologic; Humans; Isoquinolines; Oligodeoxyribonucleotides, Antisense; Peptide Fragments; Protein Serine-Threonine Kinases; Receptors, Corticotropin-Releasing Hormone; Recombinant Proteins; Retinoblastoma; RNA, Messenger; Sulfonamides; Transcription, Genetic; Transfection; Tumor Cells, Cultured

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; beta-Galactosidase; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression Regulation, Enzymologic; Genes, Reporter; Immediate-Early Proteins; Isoquinolines; Kinetics; Luciferases; Mitogen-Activated Protein Kinases; PC12 Cells; Phenylethanolamine N-Methyltransferase; Promoter Regions, Genetic; Rats; Signal Transduction; Sulfonamides; Transcription Factors; Transfection

Topics: Animals; Binding Sites; Colforsin; CREB-Binding Protein; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; E1A-Associated p300 Protein; Enzyme Inhibitors; Epidermal Growth Factor; ets-Domain Protein Elk-1; Flavonoids; Isoquinolines; Mitogen-Activated Protein Kinases; Nuclear Proteins; Pituitary Neoplasms; Potassium Channels; Prolactin; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; rap1 GTP-Binding Proteins; Rats; Sulfonamides; Thyrotropin-Releasing Hormone; Trans-Activators; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Autocrine Communication; Calcium; Calcium Channels, L-Type; Cattle; Cells, Cultured; Chromaffin Cells; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enzyme Inhibitors; GABA Antagonists; Isoquinolines; Kinetics; Naloxone; Narcotic Antagonists; Patch-Clamp Techniques; Picrotoxin; Protein Kinase Inhibitors; Sulfonamides; Suramin

Topics: Animals; Arachidonic Acid; Cation Transport Proteins; Cells, Cultured; Cholecystokinin; Colforsin; DNA-Binding Proteins; Enzyme Inhibitors; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Flavonoids; Humans; Indoles; Isoquinolines; Kinetics; Maleimides; Membrane Potentials; Membrane Transport Proteins; Patch-Clamp Techniques; Pituitary Gland, Anterior; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinase Inhibitors; Protein Kinases; Rats; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Trans-Activators; Transcriptional Regulator ERG; Tyrphostins; Vasoactive Intestinal Peptide

Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cysteine; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Glutathione Transferase; Humans; Immunoblotting; Isoquinolines; Mevalonic Acid; Mice; Models, Biological; Mutation; Peutz-Jeghers Syndrome; Phosphorylation; Precipitin Tests; Protein Prenylation; Protein Serine-Threonine Kinases; Rats; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfonamides; Time Factors; Transfection

Topics: Animals; Colforsin; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Glioma; Imidazoles; Isoquinolines; Lipopolysaccharides; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; RNA, Messenger; Sulfonamides; Transcription, Genetic; Tumor Cells, Cultured

Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glycine; Goldfish; Isoquinolines; Membrane Potentials; Patch-Clamp Techniques; Receptors, GABA-A; Receptors, Glycine; Retina; Sulfonamides

Topics: Adipocytes; Animals; Carrier Proteins; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Ion Channels; Isoquinolines; Membrane Proteins; Mice; Mitochondrial Proteins; Norepinephrine; Oxygen Consumption; Receptors, Adrenergic, beta-3; Signal Transduction; Sulfonamides; Uncoupling Protein 1

Topics: Animals; Colforsin; Cyclic AMP; Cytoplasmic Vesicles; Elasticity; Exocytosis; Isoquinolines; Rabbits; Stress, Mechanical; Sulfonamides; Time Factors; Urinary Bladder; Urine

Topics: Adenosine Triphosphatases; Bucladesine; Calcium; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans; Isoquinolines; Lymphocytes; Microscopy, Fluorescence; Milrinone; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rolipram; Sulfonamides; Thapsigargin; Time Factors

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Adenylyl Imidodiphosphate; Animals; Bungarotoxins; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Electrophysiology; Enzyme Inhibitors; Imidazoles; Insecta; Insecticides; Isoquinolines; Median Nerve; Neonicotinoids; Neurons; Niacin; Nitro Compounds; Okadaic Acid; Permeability; Phosphoprotein Phosphatases; Phosphorylation; Receptors, Nicotinic; Signal Transduction; Sulfonamides

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenine; Adenylyl Cyclases; Animal Communication; Animals; Arousal; Brain; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Female; Grasshoppers; GTP-Binding Proteins; Insect Proteins; Isoquinolines; Male; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nerve Tissue Proteins; Receptors, Muscarinic; Second Messenger Systems; Species Specificity; Sulfonamides; Thionucleotides

Topics: Animals; Antineoplastic Agents; Bucladesine; Calcium; Cinnamates; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Inhibitors; Exocytosis; Gastric Mucosa; Guinea Pigs; Isoquinolines; Male; Microscopy, Video; Pyloric Antrum; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfonamides

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Guanine Nucleotide Exchange Factors; Humans; Immunosuppressive Agents; Interleukin-5; Isoquinolines; Lymphocyte Activation; Phosphorylation; rap1 GTP-Binding Proteins; Rolipram; Sulfonamides; T-Lymphocytes

Topics: Amino Acid Sequence; Animals; Binding Sites; Chromatography, High Pressure Liquid; Colforsin; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Glutathione Transferase; Isoenzymes; Isoquinolines; Mutagenesis, Site-Directed; PC12 Cells; Peptide Fragments; Peptide Mapping; Phosphorylation; Phosphoserine; Proto-Oncogene Proteins c-raf; Rats; Recombinant Fusion Proteins; Sulfonamides; Trypsin

Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Calcium Signaling; Carbachol; Chlorides; Cholinergic Agonists; Colforsin; Cyclic AMP; Enzyme Inhibitors; Gastrointestinal Agents; Isoproterenol; Isoquinolines; Membrane Potentials; Pancreas; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Potassium Channels; Rats; Secretin; Sulfonamides; Vasoactive Intestinal Peptide

Topics: Androstadienes; Benzylamines; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Epithelial Cells; Flavonoids; Genistein; Humans; Indoles; Interleukin-8; Isoquinolines; Lung; Maleimides; Okadaic Acid; Pertussis Toxin; Protein Kinase C; Signal Transduction; Sodium Fluoride; Sulfonamides; Tetradecanoylphorbol Acetate; Vanadates; Virulence Factors, Bordetella; Wortmannin

Topics: Adenylyl Cyclase Inhibitors; Amyloid; Blotting, Northern; Carcinoma, Pancreatic Ductal; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Humans; Islet Amyloid Polypeptide; Isoquinolines; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Apoptosis; Clonidine; Colforsin; Culture Techniques; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cysteine Proteinase Inhibitors; Isoquinolines; Melanophores; Norepinephrine; Oligopeptides; Oryzias; Phenylephrine; Prazosin; Protein Isoforms; Receptors, Adrenergic, alpha-2; Signal Transduction; Skin; Skin Pigmentation; Sulfonamides; Yohimbine

Topics: Animals; Caffeine; Calcium; Calcium Channels; Calcium Signaling; Carbachol; Cholinergic Agonists; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoquinolines; Mice; Parotid Gland; Phosphorylation; Receptors, Cytoplasmic and Nuclear; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sulfonamides

Topics: Adrenergic Agonists; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Isoproterenol; Isoquinolines; Receptors, Adrenergic, beta-1; RNA, Messenger; Sulfonamides; Tumor Cells, Cultured

Topics: Bucladesine; Cell Differentiation; Colforsin; CREB-Binding Protein; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytokines; Dinoprostone; Enzyme Inhibitors; Gene Expression Regulation; Histamine; Humans; Isoquinolines; Macrophages; Monocytes; Nuclear Proteins; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, LDL; Receptors, Oxidized LDL; RNA, Messenger; Scavenger Receptors, Class E; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Trans-Activators; Tumor Cells, Cultured; Up-Regulation

Topics: Adenylyl Cyclases; Animals; Chelating Agents; Colforsin; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Enzyme Inhibitors; In Vitro Techniques; Indoles; Interneurons; Isoquinolines; Long-Term Potentiation; Maleimides; Mossy Fibers, Hippocampal; Phorbol Esters; Protein Kinase C; Rats; Rats, Wistar; Sulfonamides; Synapses

Topics: Animals; Biological Transport; Carcinogens; Cells, Cultured; Chickens; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; Indoles; Isoquinolines; Kidney Tubules, Proximal; Maleimides; Parathyroid Hormone; Phosphates; Protein Kinase C; Sodium-Phosphate Cotransporter Proteins; Sulfonamides; Symporters; Tetradecanoylphorbol Acetate

Topics: Adenylyl Cyclases; Animals; Benzazepines; Calcium; Cesium; Chlorides; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide-Gated Cation Channels; Dentate Gyrus; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; In Vitro Techniques; Ion Channels; Isoquinolines; Long-Term Potentiation; Membrane Potentials; Membrane Proteins; Models, Neurological; Mossy Fibers, Hippocampal; Nerve Tissue Proteins; Patch-Clamp Techniques; Potassium; Potassium Channels; Presynaptic Terminals; Pyramidal Cells; Pyrimidines; Rats; Rats, Sprague-Dawley; Sulfonamides; Synaptic Transmission

Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Heart Failure; Homeostasis; Immunoblotting; Intracellular Fluid; Isoproterenol; Isoquinolines; Male; Myocardial Infarction; Myocardium; Phosphorylation; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sulfonamides

Topics: Animals; Calcineurin; Calcineurin Inhibitors; Calcium; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Islets of Langerhans; Isoquinolines; NFATC Transcription Factors; Nuclear Proteins; Peptide Fragments; Promoter Regions, Genetic; Protein Precursors; Rats; Sulfonamides; Tacrolimus; Transcription Factors; Transcription, Genetic

Topics: Adrenergic beta-Agonists; Amiloride; Animals; Antiporters; Calcium; Cells, Cultured; Chelating Agents; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Diuretics; Egtazic Acid; Enzyme Inhibitors; Epithelial Cells; Extravascular Lung Water; Isoproterenol; Isoquinolines; Membrane Potentials; Patch-Clamp Techniques; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Sodium; Sodium Channels; Sulfonamides; Terbutaline

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Adrenocorticotropic Hormone; Aging; Animals; Carrier Proteins; Colforsin; Corticosterone; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Desoxycorticosterone; Female; Intracellular Signaling Peptides and Proteins; Isoquinolines; Ovariectomy; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Prolactin; Rats; Rats, Sprague-Dawley; Sulfonamides; Zona Fasciculata; Zona Reticularis

Topics: Animals; Bone Marrow Cells; Bucladesine; Carrier Proteins; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Gene Expression; Genes, Reporter; Glycoproteins; Gravitation; Isoquinolines; Luciferases; Membrane Glycoproteins; Osteoprotegerin; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; RNA, Messenger; Stromal Cells; Sulfonamides

Topics: 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Dynamins; Endocytosis; Enzyme Activation; Enzyme Inhibitors; Genetic Vectors; Glutathione Transferase; GTP Phosphohydrolases; GTPase-Activating Proteins; Humans; Immunoblotting; Inhibitory Concentration 50; Isoproterenol; Isoquinolines; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Precipitin Tests; Protein Binding; rap1 GTP-Binding Proteins; Rats; src-Family Kinases; Sulfonamides; Time Factors; Transcriptional Activation; Transfection

Topics: Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Injections, Spinal; Isoquinolines; Macaca fascicularis; Male; Neurons; Physical Stimulation; Spinothalamic Tracts; Sulfonamides

Topics: Action Potentials; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Enzyme Activators; Enzyme Inhibitors; Epilepsy; Hippocampus; Isoquinolines; Male; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Rolipram; Seizures; Sulfonamides; Thionucleotides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Calcium; Cell Line, Transformed; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gonadotropin-Releasing Hormone; Isoquinolines; Neurons; Protein Kinase C; Sodium; Sulfonamides; Tetrodotoxin

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Cell Division; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Gene Expression; Guanidines; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Interleukin-6; Isoquinolines; Melanoma; Polymerase Chain Reaction; Receptors, Interleukin-6; Skin Neoplasms; Sulfonamides; Tumor Cells, Cultured

Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Carps; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Growth Hormone; Imines; In Vitro Techniques; Ionophores; Isoquinolines; Neuropeptides; Neurotransmitter Agents; Nifedipine; Phosphodiesterase Inhibitors; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Signal Transduction; Sulfonamides; Vasoactive Intestinal Peptide

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cell Differentiation; Cell Line; Cell Size; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Green Fluorescent Proteins; Hippocampus; Isoquinolines; Luminescent Proteins; Neurons; Oligopeptides; Rats; Recombinant Fusion Proteins; Signal Transduction; Stem Cells; Sulfonamides

Topics: Amino Acid Substitution; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Isoquinolines; Molecular Mimicry; Phosphorylation; Protein Subunits; Proto-Oncogene Proteins; Rats; Recombinant Proteins; RGS Proteins; Serine; Signal Transduction; Sulfonamides; Threonine; Tumor Cells, Cultured

Topics: Adenylyl Cyclases; Alkaloids; Blood Platelets; Carbazoles; Cell Adhesion; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Indoles; Isoquinolines; Neutrophils; P-Selectin; Phosphorylation; Platelet Activation; Protein Processing, Post-Translational; Second Messenger Systems; Sulfonamides; Thrombin

Topics: Agouti-Related Protein; alpha-MSH; Animals; Arrestins; beta-Adrenergic Receptor Kinases; beta-Arrestins; Colforsin; COS Cells; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dynamin I; Endocytosis; Enzyme Inhibitors; Gene Expression; Green Fluorescent Proteins; Hemagglutinins; Humans; Hypothalamus, Middle; Indicators and Reagents; Isoquinolines; Kidney; Luminescent Proteins; Mice; Peptide Fragments; Phosphorylation; Receptor, Melanocortin, Type 4; Receptors, Corticotropin; Serine; Signal Transduction; Sulfonamides; Threonine

Topics: Adrenomedullin; Bucladesine; Cell Differentiation; Cell Division; Cells, Cultured; Chondrocytes; Colforsin; Culture Media, Conditioned; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Isoquinolines; Membrane Proteins; Peptides; Phenotype; Radioimmunoassay; Receptor Activity-Modifying Proteins; Receptors, Adrenomedullin; Receptors, Peptide; Sulfonamides; Time Factors

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Barium; Cadmium; Calcium Channel Blockers; Calcium Channels; Clonidine; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 4; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Heterotrimeric GTP-Binding Proteins; Imines; In Vitro Techniques; Isoquinolines; Long-Term Potentiation; Long-Term Synaptic Depression; Membrane Potentials; Mice; Norepinephrine; omega-Agatoxin IVA; omega-Conotoxins; Patch-Clamp Techniques; Pertussis Toxin; Piperazines; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Pyridines; Receptors, Adrenergic, alpha-2; Serotonin Antagonists; Sulfonamides; Yohimbine

Topics: Ascomycota; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activators; Enzyme Inhibitors; Flavonoids; Hordeum; Hyphae; Isoquinolines; Mitogen-Activated Protein Kinases; Pertussis Toxin; Signal Transduction; Sphingosine; Sulfonamides; Time Factors

Topics: Androstenedione; Animals; Cells, Cultured; Colforsin; Cordyceps; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Hydroxycholesterols; Isoquinolines; Leydig Cells; Male; Mice; Mice, Inbred C57BL; Mycelium; Progestins; Protein Kinase C; Staurosporine; Sulfonamides; Testosterone; Tetradecanoylphorbol Acetate

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Carcinogens; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Indoles; Isoquinolines; Neurons; Phosphorylation; Protein Kinase C; Receptors, Nicotinic; Sulfonamides; Tetradecanoylphorbol Acetate; Thionucleotides; Transfection

Topics: Active Transport, Cell Nucleus; Animals; Calcium; Cell Differentiation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Flavonoids; Isoquinolines; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neurites; PC12 Cells; Phosphorylation; Potassium Chloride; Protein Serine-Threonine Kinases; Rats; Signal Transduction; Sulfonamides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antihypertensive Agents; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Carcinogens; Cells, Cultured; Colforsin; Corpus Striatum; Cyclic AMP; Drug Interactions; Embryo, Mammalian; Enkephalins; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Humans; Isoquinolines; Neurons; Nifedipine; Protein Precursors; Pyrroles; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection

Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Enzyme Inhibitors; Gene Expression Regulation; Insulin-Like Growth Factor I; Isoquinolines; Osteoblasts; Parathyroid Hormone; Peptide Fragments; Rats; Receptors, Parathyroid Hormone; RNA, Messenger; Signal Transduction; Sulfonamides; Thionucleotides; Tumor Cells, Cultured

Topics: Action Potentials; Adenosine; Affinity Labels; Animals; Colforsin; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Enkephalins; Enzyme Inhibitors; gamma-Aminobutyric Acid; In Vitro Techniques; Isoquinolines; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Probenecid; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Substance Withdrawal Syndrome; Sulfonamides; Synaptic Transmission; Thioinosine; Time Factors; Uricosuric Agents; Vasodilator Agents; Xanthines

Topics: Animals; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Glomerular Mesangium; Isoquinolines; Male; Rats; Rats, Wistar; Sulfonamides

Topics: alpha-MSH; Animals; Cell Differentiation; Colforsin; Isoquinolines; Melanoma, Experimental; Mice; Mitogen-Activated Protein Kinases; Models, Chemical; p38 Mitogen-Activated Protein Kinases; Pentacyclic Triterpenes; Phosphorylation; Structure-Activity Relationship; Sulfonamides; Triterpenes; Tumor Cells, Cultured

Topics: Adenine; Adenylyl Cyclases; Blood Proteins; Cell Adhesion Molecules; Cilostazol; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Humans; Isoquinolines; Kinetics; Microfilament Proteins; Nitroprusside; Phosphodiesterase Inhibitors; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Sulfonamides; Tetrazoles

Topics: Blotting, Northern; Blotting, Western; Carrier Proteins; Cell Line, Tumor; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Gene Expression; Humans; Isoquinolines; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Membrane Glycoproteins; Metalloendopeptidases; Osteoblasts; Protein Kinase C; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Signal Transduction; Staurosporine; Sulfonamides; Teriparatide

Topics: Alitretinoin; Alleles; Animals; Apolipoprotein A-I; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biotinylation; Catalytic Domain; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Humans; Hydroxycholesterols; Isoquinolines; Lipid Metabolism; Mutation; Phosphorylation; Precipitin Tests; Protein Binding; Signal Transduction; Sulfonamides; Tangier Disease; Time Factors; Transfection; Tretinoin

Topics: Androgen Antagonists; Anilides; Blotting, Western; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dihydrotestosterone; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Humans; Hydroxyprostaglandin Dehydrogenases; Interleukin-6; Isoquinolines; Kinetics; Male; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; STAT3 Transcription Factor; Sulfonamides; Tosyl Compounds; Trans-Activators; Tumor Cells, Cultured

Topics: 6-Ketoprostaglandin F1 alpha; Acetophenones; Alprostadil; Arteriosclerosis; Becaplermin; Benzopyrans; Bucladesine; Carotid Artery Diseases; Carotid Artery, Internal; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Enzyme Induction; Epoprostenol; Extracellular Matrix; Glucuronosyltransferase; Humans; Hyaluronan Synthases; Hyaluronic Acid; Iloprost; Indoles; Isoenzymes; Isoquinolines; Macrophages; Maleimides; Membrane Proteins; Muscle Cells; Muscle, Smooth, Vascular; Pertussis Toxin; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-sis; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; RNA, Small Interfering; Sulfonamides; Vasodilator Agents

Topics: Amino Acids; Animals; Anticonvulsants; Avoidance Learning; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclopropanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Isoquinolines; Male; Memory; Mice; Reaction Time; Receptors, Metabotropic Glutamate; Rolipram; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Xanthenes

Topics: Animals; Blotting, Northern; Bucladesine; Cell Line; Colforsin; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gene Expression Regulation; Isoquinolines; Lipopolysaccharides; Mice; Microglia; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Time Factors

Topics: Adenylyl Cyclases; Alkaline Phosphatase; Alprostadil; Animals; Bucladesine; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Imidazoles; Isoquinolines; Mice; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sulfonamides

Topics: Adenylyl Cyclases; Animals; Antineoplastic Agents; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Epoprostenol; In Vitro Techniques; Isoquinolines; Muscle, Smooth, Vascular; Protein Kinase C; Pulmonary Artery; Rats; Sulfonamides; Vasodilator Agents

Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Female; Interferon-gamma; Isoquinolines; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Phosphorylation; Signal Transduction; Sulfonamides

Topics: Animals; Bumetanide; Butadienes; Cell Line; Chromones; Colforsin; Cyclic AMP; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Gastrointestinal Tract; Indoles; Isoproterenol; Isoquinolines; Maleimides; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Skeletal; Nitriles; Potassium; Rats; Rubidium Radioisotopes; Sodium-Potassium-Chloride Symporters; Sulfonamides

Topics: Analgesics, Opioid; Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Colforsin; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Activation; Enzyme Inhibitors; Female; Indoles; Isoquinolines; Male; Maleimides; Membrane Potentials; Narcotics; Patch-Clamp Techniques; Posterior Horn Cells; Potassium Channel Blockers; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetrodotoxin

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Carbazoles; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclooxygenase 2; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Immunoblotting; Indoles; Isoquinolines; Jurkat Cells; Luciferases; Membrane Proteins; NFATC Transcription Factors; Nuclear Proteins; Plasmids; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Binding; Pyrroles; RNA, Messenger; Rolipram; Sulfonamides; T-Lymphocytes; Transcription Factors; Transcriptional Activation; Transfection

Topics: Adenylyl Cyclases; Blotting, Western; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Female; Guanine Nucleotide Exchange Factors; Humans; Isoquinolines; Luteal Cells; Luteinizing Hormone; Progesterone; Sulfonamides

Topics: Alprostadil; Blood Coagulation; Bucladesine; Carotid Artery Diseases; Carotid Artery, Internal; Cells, Cultured; Colforsin; Coronary Vessels; Culture Media, Serum-Free; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Epoprostenol; Etoricoxib; Gene Expression Profiling; Gene Expression Regulation; Humans; Iloprost; Isoquinolines; Mammary Arteries; Membrane Proteins; Models, Biological; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyridines; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; RNA, Messenger; Saphenous Vein; Second Messenger Systems; Sulfonamides; Sulfones; Tetradecanoylphorbol Acetate; Thrombomodulin; Thrombophilia; Vasodilator Agents

Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Guinea Pigs; Heart Ventricles; Isoquinolines; Membrane Proteins; Microscopy, Fluorescence; Myocytes, Cardiac; Patch-Clamp Techniques; Phosphoproteins; Phosphorylation; Protein Isoforms; Serine; Sodium-Potassium-Exchanging ATPase; Sulfonamides

Topics: Animals; Antibody Specificity; Aquaporin 2; Aquaporins; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dogs; Dopamine; Endocytosis; Isoquinolines; Kidney; Male; Phosphorylation; Protein Kinase Inhibitors; Protein Transport; Rats; Rats, Sprague-Dawley; Renal Agents; Serine; Sulfonamides; Vasopressins

Topics: Amino Acid Transport System X-AG; Analgesics, Opioid; Analysis of Variance; Animals; Blotting, Western; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dideoxyadenosine; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Isoquinolines; Male; Morphine; Nicotinic Acids; Pain Measurement; Protein Kinase Inhibitors; Rats; Spinal Cord; Sulfonamides; Symporters; Time Factors

Topics: 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Benzoquinones; Colforsin; Cyclic AMP; Female; Isoquinolines; Lactams, Macrocyclic; Mice; Mice, Inbred C57BL; Ovary; Progesterone; Promoter Regions, Genetic; Protein Kinase Inhibitors; Quinones; Reverse Transcriptase Polymerase Chain Reaction; Rifabutin; RNA, Messenger; src-Family Kinases; Steroid 17-alpha-Hydroxylase; Sulfonamides; Theca Cells

Topics: Animals; Animals, Newborn; Bicuculline; Brain Stem; Catecholamines; Cell Count; Colforsin; Drug Interactions; GABA Antagonists; Gene Expression Regulation, Developmental; Immunohistochemistry; In Situ Hybridization; In Vitro Techniques; Isoquinolines; Membrane Glycoproteins; Membrane Transport Proteins; Neurons; Norepinephrine Plasma Membrane Transport Proteins; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Sulfonamides; Symporters; Tetrodotoxin; Tyrosine 3-Monooxygenase; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

Topics: Androstenedione; Animals; Butadienes; Cattle; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblast Growth Factor 2; Isoquinolines; Luteinizing Hormone; Nitriles; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Progesterone; Protein Kinase Inhibitors; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Sulfonamides; Tetradecanoylphorbol Acetate; Theca Cells

Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diazoxide; Enzyme Activation; Glucose; Insulin; Insulin Secretion; Intracellular Signaling Peptides and Proteins; Islets of Langerhans; Isoquinolines; Male; Mice; Ouabain; Potassium; Potassium Channels; Protein Kinase C; Sulfonamides

Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Animals, Newborn; Behavior, Animal; Blotting, Western; Colforsin; Cyclic AMP; Dose-Response Relationship, Radiation; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Imines; In Vitro Techniques; Isoquinolines; Male; Membrane Potentials; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Oxidoreductases; Pain; Pain Measurement; Patch-Clamp Techniques; Pyrimidines; Raphe Nuclei; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides

Topics: Aluminum Chloride; Aluminum Compounds; Animals; Calcium Channels; Cell Separation; Chlorides; Colforsin; Cyclic AMP-Dependent Protein Kinases; Diterpenes; Dose-Response Relationship, Drug; Ginkgo biloba; Ginkgolides; Hippocampus; Isoquinolines; Lactones; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Rats; Rats, Wistar; Sulfonamides

Topics: Amides; Animals; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzymes; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Isoquinolines; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Pyridines; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; Sulfonamides; Thymidine; Trapidil; Tritium

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Aminopyridines; Benzamides; Biotransformation; Blotting, Western; Cell Line; Chlorides; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Activation; Humans; Iodine Radioisotopes; Isoquinolines; Phosphodiesterase Inhibitors; Sulfonamides

Topics: Animals; Base Sequence; Blotting, Western; Cattle; Cell Nucleus; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; DNA; DNA-Binding Proteins; DNA, Complementary; Enzyme Inhibitors; Female; Genes, Dominant; Genes, Reporter; Granulosa Cells; Immunoprecipitation; Isoquinolines; Molecular Sequence Data; Phosphorylation; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Structure, Tertiary; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Sulfonamides; Time Factors; Transcription Factors; Transcriptional Activation; Transfection; Upstream Stimulatory Factors

Topics: Cell Line; Cell Membrane; Cell Membrane Permeability; Chlorides; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Epithelial Cells; Fluorescent Antibody Technique; Guanylate Cyclase; Humans; Intestinal Mucosa; Intestines; Isoquinolines; Nitric Oxide; Nitric Oxide Donors; Nocodazole; Oxadiazoles; Quinoxalines; Sulfonamides

Topics: Animals; Bucladesine; Caspase 3; Caspases; Cell Differentiation; Cell Survival; Colforsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Intracellular Membranes; Isoquinolines; MAP Kinase Signaling System; Membrane Potentials; Mitochondria; Nerve Growth Factors; Neurons; Neuropeptides; Neurosecretory Systems; Neurotransmitter Agents; p38 Mitogen-Activated Protein Kinases; Parkinson Disease; PC12 Cells; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Kinase Inhibitors; Rats; Rotenone; Signal Transduction; Sulfonamides

Topics: Alanine; Aminobutyrates; Analysis of Variance; Animals; Benzoates; Colforsin; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Immunohistochemistry; Isoquinolines; Male; Microdialysis; Microscopy, Immunoelectron; Periaqueductal Gray; Phosphoserine; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Sulfonamides; Time Factors

Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Isoquinolines; Mice; Mutation; NIH 3T3 Cells; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Signal Transduction; Sulfonamides; Transcription, Genetic

Topics: Androstadienes; Animals; bcl-Associated Death Protein; Blotting, Western; Cell Count; Cell Proliferation; Chromones; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Gene Silencing; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Immunoprecipitation; Isoquinolines; Macrophages; Mice; Mice, Inbred C57BL; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; rap1 GTP-Binding Proteins; RNA Interference; RNA, Double-Stranded; Serine; Signal Transduction; Sulfonamides; Threonine; Thymidine; Time Factors; Up-Regulation; Wortmannin; X-Linked Inhibitor of Apoptosis Protein

Topics: Animals; Base Sequence; Cell Line, Tumor; Colforsin; Connexins; Cyclic AMP; Cyclic AMP Response Element Modulator; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Down-Regulation; Flavonoids; Gap Junction delta-2 Protein; Glucose; Humans; Insulin-Secreting Cells; Isoquinolines; Mitogen-Activated Protein Kinases; Nifedipine; Promoter Regions, Genetic; Rats; Response Elements; RNA, Messenger; Sequence Deletion; Sulfonamides; Tetradecanoylphorbol Acetate

Topics: Animals; Brain; Brain Ischemia; Calibration; Colforsin; Coumaric Acids; Cyclic AMP; Cytoplasm; Endothelial Cells; Enzyme Inhibitors; Hydrogen-Ion Concentration; Immunohistochemistry; Isoproterenol; Isoquinolines; Kinetics; Microscopy, Fluorescence; Models, Biological; Monocarboxylic Acid Transporters; Radioimmunoassay; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sulfonamides; Symporters

Topics: 3T3 Cells; Adipocytes; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dactinomycin; Flavonoids; Humans; Interleukin-6; Isoquinolines; Mice; Protein Synthesis Inhibitors; Signal Transduction; Sulfonamides; Thyroid Gland; Thyrotropin

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arginine Vasopressin; Calcium; Cell Line; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Immunoblotting; Indoles; Isoquinolines; Kidney; Membrane Transport Proteins; Mice; Sulfonamides; Urea; Urea Transporters

Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Cell Line; Cell Membrane; Clozapine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Ergolines; Gene Expression; Humans; Isoproterenol; Isoquinolines; Methiothepin; Multivariate Analysis; Phenols; Protein Isoforms; Protein Kinase Inhibitors; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Time Factors; Tritium

Topics: Adenylyl Cyclases; Androstadienes; Animals; Animals, Newborn; Cell Line; Cell Proliferation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Enzyme Activation; Flavonoids; Gastric Inhibitory Polypeptide; Glucagon-Like Peptide 1; Human Growth Hormone; Imidazoles; Insulin-Secreting Cells; Isoquinolines; Liraglutide; Mitogen-Activated Protein Kinase Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Rats; Signal Transduction; Stimulation, Chemical; Sulfonamides; Transcription, Genetic; Transduction, Genetic; Wortmannin

Topics: Animals; Blotting, Western; Cell Line; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Dose-Response Relationship, Drug; Exenatide; Flavonoids; Gene Expression; Glucagon-Like Peptide-1 Receptor; Insulin-Secreting Cells; Isoquinolines; Mitogen-Activated Protein Kinase Kinases; Mutagenesis, Site-Directed; Peptides; Phosphorylation; Proto-Oncogene Proteins c-raf; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Response Elements; RNA, Messenger; Sulfonamides; Venoms

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Biological Transport; Cell Line; Colforsin; Cyclic AMP; Dogs; Drug Synergism; Enzyme Activation; Isoquinolines; Kidney; Membrane Transport Proteins; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Sulfonamides; Transfection; Urea; Urea Transporters; Vasopressins

Topics: Animals; Antibodies; Bone Resorption; Carbazoles; Cathepsin K; Cathepsins; Cells, Cultured; Chloroquine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Isoquinolines; Lysosomes; Mannose; Mice; Monensin; Naphthalenes; Osteoclasts; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Pyrroles; Receptor, IGF Type 2; Signal Transduction; Sulfonamides

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine A2 Receptor Agonists; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Data Interpretation, Statistical; Enzyme Inhibitors; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Globus Pallidus; In Vitro Techniques; Isoquinolines; Male; Okadaic Acid; Phenethylamines; Rats; Rats, Wistar; Sulfonamides; Synapses; Triazines; Triazoles

Topics: Adiponectin; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Blotting, Western; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophoresis, Polyacrylamide Gel; Endothelial Cells; Enzyme Activation; Glucose; Humans; Hydrogen Peroxide; Isoquinolines; Lipoproteins, LDL; Multienzyme Complexes; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Recombinant Proteins; Ribonucleosides; Signal Transduction; Sulfonamides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Chromans; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Cytochalasin D; Cytoskeleton; GTP-Binding Proteins; Guinea Pigs; Indoles; Isoquinolines; KCNQ1 Potassium Channel; Maleimides; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Osmotic Pressure; Phosphatidylinositol 3-Kinases; Potassium Channels; Protein Kinase C; Protein-Tyrosine Kinases; Sulfonamides; Tetradecanoylphorbol Acetate; Tyrphostins

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cell Line, Tumor; Cell Movement; Cilia; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Epithelial Cells; Fluorescence Resonance Energy Transfer; Forkhead Transcription Factors; Humans; Immunohistochemistry; Isoquinolines; Kinetics; Luminescent Proteins; Lung; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Subunits; Recombinant Fusion Proteins; Sulfonamides; Thionucleotides; Time Factors

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Proliferation; Chick Embryo; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Germ Cells; Isoquinolines; Phorbol Esters; Protein Kinase C; Sulfonamides

Topics: alpha-MSH; Arrestins; beta-Arrestin 2; beta-Arrestins; Binding, Competitive; Biological Transport; Caveolae; Cell Line; Clathrin-Coated Vesicles; Colforsin; Cyclic AMP-Dependent Protein Kinases; Green Fluorescent Proteins; Humans; Isoquinolines; Kinetics; Melanocyte-Stimulating Hormones; Microscopy, Confocal; Microscopy, Fluorescence, Multiphoton; Models, Molecular; Peptides, Cyclic; Receptors, Melanocortin; Rhodamines; Signal Transduction; Sulfonamides; Transfection

Topics: Animals; Cells, Cultured; Chromatin Immunoprecipitation; Colforsin; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Dactinomycin; Gene Expression Regulation; Isoquinolines; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Models, Biological; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Messenger; Sulfonamides; Up-Regulation

Topics: Adrenergic beta-Agonists; Animals; Benzylamines; Calcium; Calcium Channels, L-Type; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Diastole; Heart Failure; Isoproterenol; Isoquinolines; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Peptides; Phosphorylation; Protein Processing, Post-Translational; Rabbits; Receptors, Adrenergic, beta; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Signal Transduction; Sulfonamides; Tetracaine

Topics: Alcohols; Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cerebellum; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Genetic Vectors; Green Fluorescent Proteins; Isoquinolines; Mice; Mice, Knockout; Neurons; Nitric Oxide Synthase Type I; Signal Transduction; Sulfonamides; Time Factors

Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Southern; Cattle; Cells, Cultured; Chorionic Gonadotropin; Cloning, Molecular; Colforsin; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; DNA Primers; Enzyme Activation; Female; Follicular Phase; Gene Expression Regulation; Gonadotropins; Granulosa Cells; Humans; Intestines; Isoquinolines; Male; Molecular Sequence Data; Ovarian Follicle; Ovulation; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Rats; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I; Receptors, Vasoactive Intestinal Peptide, Type II; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Sulfonamides; Testis; Theca Cells; Transfection; Uterus

Topics: Adenylyl Cyclases; Amino Acid Transport System A; Animals; Astrocytes; Carrier Proteins; Cell Survival; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Hydrogen Peroxide; Isoquinolines; Mutation; Neocortex; Neurons; Oxidative Stress; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Sulfonamides; Time Factors; Transcription Factor AP-1; Transfection; Up-Regulation

Topics: Algorithms; Animals; Biological Transport, Active; Butadienes; Cations; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP-Dependent Protein Kinases; Enzyme Activators; Enzyme Inhibitors; Epidermal Growth Factor; Isoquinolines; Kidney; Kidney Tubules, Proximal; Kinetics; Mitogen-Activated Protein Kinases; Nitriles; Organic Cation Transport Proteins; Rabbits; Recombinant Proteins; Sulfonamides; Tetraethylammonium Compounds

Topics: Adenylyl Cyclases; Amygdala; Animals; Calcium Signaling; Colforsin; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Isoquinolines; Long-Term Potentiation; Long-Term Synaptic Depression; Neuronal Plasticity; Neurons, Afferent; Nociceptors; Okadaic Acid; Pain; Phosphoprotein Phosphatases; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Synaptic Transmission

Topics: 3T3 Cells; Animals; Butadienes; Calcium-Binding Proteins; Colforsin; Cyclic AMP-Dependent Protein Kinases; Extracellular Matrix Proteins; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Indoles; Isoquinolines; Maleimides; Matrix Gla Protein; Mice; Nitriles; Osteoblasts; Parathyroid Hormone; Promoter Regions, Genetic; Protein Kinase C; Recombinant Proteins; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate

Topics: 3T3-L1 Cells; Adenylyl Cyclases; Adipocytes; Adiponectin; Adrenergic beta-Agonists; AMP-Activated Protein Kinases; Animals; Blotting, Western; Colforsin; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Ethanolamines; Fenoterol; Gene Expression Regulation; Isoproterenol; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Multienzyme Complexes; Protein Serine-Threonine Kinases; Receptors, Adiponectin; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tumor Necrosis Factor-alpha; Up-Regulation

Topics: Adrenergic alpha-Agonists; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Escherichia coli; Isoquinolines; Macrophages; Mice; Norepinephrine; Phagocytosis; Protein Kinase Inhibitors; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Spleen; Sulfonamides; Wounds and Injuries

Topics: Amyloid beta-Peptides; Animals; Animals, Newborn; Behavior, Animal; Colforsin; Dose-Response Relationship, Immunologic; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Hippocampus; In Vitro Techniques; Isoquinolines; Long-Term Potentiation; Male; Mice; Neural Inhibition; Peptide Fragments; Protein Kinase Inhibitors; Sulfonamides; Swimming; Time Factors

Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Exocytosis; Glucagon-Like Peptide 1; Guanine Nucleotide Exchange Factors; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Male; Membrane Fusion; Microscopy, Fluorescence; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Secretory Vesicles; Sulfonamides

Topics: Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Ganglia, Spinal; Histamine; Histamine Agonists; Inositol 1,4,5-Trisphosphate; Isoquinolines; Models, Biological; Neurons, Afferent; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfonamides; Time Factors

Topics: Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; Heart Ventricles; Isoproterenol; Isoquinolines; Male; Mice; Myocardium; Myocytes, Cardiac; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate; Troponin I

Topics: Adult; Blotting, Western; Cells, Cultured; Colforsin; Cyclic AMP; Female; Humans; Interleukin-1beta; Isoquinolines; Medroxyprogesterone; Muscle Cells; NF-kappa B; Pregnancy; Progesterone; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, Prostaglandin; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Uterus

Topics: Adrenergic beta-2 Receptor Agonists; Animals; Asthma; Butadienes; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Dinoprostone; Enzyme Induction; Humans; Isoquinolines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle Contraction; Muscle Relaxation; Nitriles; Pertussis Toxin; Phosphodiesterase 4 Inhibitors; Rabbits; Receptors, G-Protein-Coupled; Rolipram; Signal Transduction; Sulfonamides; Trachea

Topics: Animals; Benzylamines; Cell Line, Tumor; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Drug Interactions; Humans; Hypothalamus; Immunoblotting; Isoquinolines; Neurons; Phorbol Esters; Phosphorylation; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Transcription, Genetic; Transfection

Topics: Alternative Splicing; Animals; Atropine; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carbachol; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Estrenes; Indoles; Isoquinolines; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscarinic Agonists; Muscarinic Antagonists; Protein Isoforms; Protein Kinase C; Pyrrolidinones; Receptors, Muscarinic; Recombinant Proteins; Signal Transduction; Sulfonamides; Transfection; Type C Phospholipases

Topics: Amides; Animals; Animals, Newborn; Brain; Cells, Cultured; Colforsin; Culture Media; Culture Media, Serum-Free; Dinoprostone; Dose-Response Relationship, Drug; Encephalitis; Hormone Antagonists; Indoles; Isoquinolines; Lipopolysaccharides; Neuroglia; Nitrobenzenes; Octreotide; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Somatostatin; Somatostatin; Sulfonamides

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Green Fluorescent Proteins; Hippocampus; Isoquinolines; Mutation; Neurons; Phosphorylation; Protein Transport; Rats; Rats, Sprague-Dawley; Serine; Shal Potassium Channels; Sulfonamides; Transfection

Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Action Potentials; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Embryo, Nonmammalian; Female; Isoquinolines; Male; Muscle Fibers, Fast-Twitch; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Stimulation, Chemical; Sulfonamides; Zebrafish

Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Stability; Excitatory Amino Acid Agonists; Hippocampus; Humans; Intracellular Signaling Peptides and Proteins; Isoquinolines; Kainic Acid; Membrane Potentials; Mice; Mice, Knockout; Neurons; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Potassium Chloride; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rats; RNA, Messenger; Seizures; Signal Transduction; Sulfonamides

Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Delayed Rectifier Potassium Channels; Electrophysiology; Isoquinolines; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Rotenone; Signal Transduction; Sulfonamides; Uncoupling Agents

Topics: Animals; Base Sequence; Brain Stem; Bucladesine; Carbazoles; Cell Line, Tumor; Colforsin; Conserved Sequence; Corticotropin-Releasing Hormone; Gene Expression; Intracellular Signaling Peptides and Proteins; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Promoter Regions, Genetic; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Relaxin; Sulfonamides

Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Enzyme Activators; Fetus; Gene Expression Regulation; Isoproterenol; Isoquinolines; Mice; Myocytes, Cardiac; Myosin Heavy Chains; Nonmuscle Myosin Type IIB; Phenylephrine; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; RNA, Messenger; Signal Transduction; Sulfonamides

Topics: Action Potentials; Animals; Animals, Newborn; Cell Size; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Dinoprostone; Electric Stimulation; Ganglia, Spinal; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Isoquinolines; Menthol; Mice; Mice, Inbred Strains; Mice, Knockout; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Wistar; Sensory Receptor Cells; Sulfonamides; TRPM Cation Channels

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aged; Antibodies; Carbazoles; Cells, Cultured; Chondrocytes; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-1beta; Isoquinolines; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Osteoarthritis; Prostaglandin D2; Pyrroles; Receptors, Immunologic; Receptors, Leukotriene B4; Receptors, Prostaglandin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Th2 Cells

Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Carbachol; Colforsin; Extracellular Space; Gastric Acid; Hydrogen-Ion Concentration; Isoquinolines; Mice; Omeprazole; Parietal Cells, Gastric; Potassium; Protein Serine-Threonine Kinases; Quaternary Ammonium Compounds; Sulfonamides; Tetradecanoylphorbol Acetate

Topics: Amino Acid Sequence; Animals; Base Sequence; Bucladesine; Colforsin; Female; Fishes; Gene Expression; Gonads; Immunohistochemistry; Isoquinolines; Male; Molecular Sequence Data; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Kinase Inhibitors; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Sulfonamides; Tilapia; Tissue Culture Techniques; Up-Regulation

Topics: Action Potentials; Analysis of Variance; Animals; Calcium; Colforsin; Cyclic AMP; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Isoquinolines; Neurons; Oligopeptides; Patch-Clamp Techniques; Protein Kinase Inhibitors; Pyridazines; Quinoxalines; Rats; Signal Transduction; Sulfonamides; Synapses; Time Factors

Topics: Blood Platelets; Calcium; Chelating Agents; Colforsin; Crotalid Venoms; Cyclic AMP-Dependent Protein Kinases; Dipeptides; Dose-Response Relationship, Drug; Edetic Acid; Humans; Intracellular Signaling Peptides and Proteins; Ionophores; Isoquinolines; Membrane Glycoproteins; Metalloproteases; P-Selectin; Peptide Fragments; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Protease Inhibitors; Sulfonamides; Thrombin; Time Factors; von Willebrand Factor

Topics: Anthracenes; Cell Line; Chromones; Colforsin; Corticotropin-Releasing Hormone; Dexamethasone; Flavonoids; Genes, Reporter; Humans; Hypothalamus; Imidazoles; Isoquinolines; Morpholines; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyridines; Regulatory Elements, Transcriptional; Sequence Deletion; Sulfonamides; Transfection

Topics: 3T3-L1 Cells; Adipocytes; Angiotensin II; Animals; Colforsin; Hypoglycemic Agents; Insulin; Interleukin-6; Isoquinolines; Lipolysis; Male; Mice; Mice, Inbred C57BL; Obesity; Protein Kinase Inhibitors; Renin; Renin-Angiotensin System; RNA, Messenger; Stem Cells; Sulfonamides; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents

Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrier Proteins; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Exocytosis; Glucose; Green Fluorescent Proteins; Immunoblotting; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Isoquinolines; Mice; Microscopy, Fluorescence; Microscopy, Immunoelectron; Mitochondrial Proteins; Okadaic Acid; Phosphorylation; Protein Transport; rab GTP-Binding Proteins; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Transfection

Topics: Adamantane; Animals; Benzenesulfonates; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic CMP; Enzyme Activators; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Isoquinolines; Membrane Potentials; Mice; Mice, Inbred ICR; Potassium; Potassium Channels, Voltage-Gated; Protein Kinase C; Protein Kinase Inhibitors; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Schwann Cells; Sciatic Nerve; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors

Topics: Acetophenones; Amylases; Animals; Benzopyrans; Bucladesine; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Isoproterenol; Isoquinolines; Male; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Naphthalenes; Parotid Gland; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Transport; Rats; Rats, Sprague-Dawley; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Exocytosis; Guanine Nucleotide Exchange Factors; Isoquinolines; Male; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Solute Carrier Family 12, Member 1; Sulfonamides

Topics: Animals; Binding Sites; Blood Platelets; Cilostazol; Colforsin; Collagen; Cyclic AMP; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; In Vitro Techniques; Isoquinolines; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolones; Rats; Rats, Sprague-Dawley; Serine; Sulfonamides; Tetrazoles

Topics: Adenocarcinoma; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Animals; Apoptosis; Bucladesine; Cell Division; Colforsin; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Enzyme Induction; Gene Knockdown Techniques; Humans; Isoquinolines; Male; Metribolone; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; RNA, Small Interfering; Signal Transduction; Sulfonamides; Tosyl Compounds

Topics: Animals; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Signal-Regulated MAP Kinases; Guanine Nucleotide Exchange Factors; Isoquinolines; Kidney Medulla; Kidney Tubules, Collecting; Male; MAP Kinase Signaling System; Membrane Transport Proteins; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Sulfonamides; Urea; Urea Transporters; Vasopressins

Topics: Adenylyl Cyclases; Bucladesine; Cell Adhesion Molecules; Cell Proliferation; Cell Separation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytokines; Dinoprostone; Enzyme Activation; Flow Cytometry; Glycation End Products, Advanced; Humans; In Vitro Techniques; Isoquinolines; Lymphocytes; Monocytes; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfonamides

Topics: Blotting, Western; Cell Line; Cell Line, Tumor; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Enzyme Activation; Estradiol; Estrogen Receptor alpha; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Isoquinolines; Luciferases; Protein Kinase Inhibitors; Protein Stability; Protein Synthesis Inhibitors; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sulfonamides

Topics: Adenylyl Cyclases; Calcineurin; Carbazoles; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Enzyme Activation; Half-Life; Humans; Intracellular Signaling Peptides and Proteins; Isoquinolines; Muscle Proteins; Neurons; Protein Kinase Inhibitors; Protein Stability; Pyrroles; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Cell Differentiation; Cell Line, Tumor; Colforsin; Cyclic GMP; Enzyme Inhibitors; Exocytosis; Humans; Isoquinolines; Microtubule-Associated Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Nitroso Compounds; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Pyridinium Compounds; Quaternary Ammonium Compounds; Signal Transduction; Sulfonamides; Synapsins; Synaptic Vesicles; Synaptotagmin I; Teratocarcinoma; Time Factors

Topics: 1-Methyl-3-isobutylxanthine; 3T3-L1 Cells; Adipocytes; Adipokines; Adiponectin; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Exenatide; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Inflammation; Insulin Resistance; Isoquinolines; Mice; Peptides; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Receptors, Glucagon; RNA, Messenger; Sulfonamides; Venoms

Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Antibodies, Monoclonal; Cell Differentiation; Chorionic Gonadotropin; Chorionic Gonadotropin, beta Subunit, Human; Colforsin; Cyclic AMP; Cycloheximide; Female; Gene Expression; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Glycoprotein Hormones, alpha Subunit; Humans; Hydrocortisone; Isoquinolines; Placenta; Pregnancy; Promoter Regions, Genetic; Protein Kinase Inhibitors; Signal Transduction; Sulfonamides; Trophoblasts

Topics: Adenoviridae; Animals; Bromocriptine; Butadienes; Cell Line, Tumor; Cells, Cultured; Colforsin; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Genes, Reporter; Insulin-Like Growth Factor I; Integrases; Isoquinolines; Lactotrophs; Ligands; Luciferases; Nitriles; Pituitary Gland, Anterior; Prolactin; Promoter Regions, Genetic; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptors, Estrogen; Response Elements; Sulfonamides; Thymidine Kinase; Transcriptional Activation; Transduction, Genetic

Topics: Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Guanine Nucleotide Exchange Factors; Humans; Interleukin-1beta; Isoquinolines; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Second Messenger Systems; Skin; Sulfonamides; Teprotide; Tumor Necrosis Factor-alpha

Topics: 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Colforsin; Enzyme Activation; Flavonoids; Interleukin-6; Isoquinolines; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteoblasts; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Sulfonamides; Tumor Necrosis Factor-alpha; Vasoactive Intestinal Peptide

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Animals; Colforsin; Cyclic AMP; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Ganglia, Invertebrate; In Vitro Techniques; Isoquinolines; Nerve Net; Neurons; Palinuridae; Patch-Clamp Techniques; Phospholipid Ethers; Potassium; Potassium Channel Blockers; Protein Kinase Inhibitors; Pylorus; Receptors, Dopamine D1; Signal Transduction; Sulfonamides; Tetraethylammonium; Tetrodotoxin

Topics: Active Transport, Cell Nucleus; Aged; Apoptosis; beta Catenin; Bone Regeneration; Calcitonin Gene-Related Peptide; Cell Survival; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Enzyme Activators; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Isoquinolines; Middle Aged; Osteoblasts; Peptide Fragments; Phosphorylation; Protein Kinase Inhibitors; Protein Stability; RNA, Messenger; Signal Transduction; Sulfonamides; Time Factors; Wnt Proteins

Topics: Animals; Animals, Newborn; Antioxidants; Benzophenanthridines; Bilirubin; Cochlear Nucleus; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Isoquinolines; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phorbol Esters; Protein Kinase C; Rats; Signal Transduction; Sulfonamides; Synaptic Transmission

Topics: Adipocytes, White; Aerobiosis; Anaerobiosis; Animals; Bucladesine; Colforsin; Cyclic AMP; Humans; Ion Channels; Isoproterenol; Isoquinolines; Male; Mice; Mice, Knockout; Mitochondrial Proteins; Oxygen Consumption; Protein Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Sulfonamides; Uncoupling Protein 2

Topics: Cell Fusion; Cell Line, Tumor; Chorionic Gonadotropin; Colforsin; Female; Fluoroimmunoassay; Galectins; Humans; Isoquinolines; Microscopy, Fluorescence; Placenta; Pregnancy; Pregnancy Proteins; Protein Kinase Inhibitors; Statistics, Nonparametric; Sulfonamides; Trophoblasts

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Infections; Cell Line; Chemokine CCL5; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Interferon-gamma; Interleukin-2; Isoquinolines; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitrobenzenes; Prostaglandin Antagonists; Protein Kinase Inhibitors; Shock, Septic; Signal Transduction; Sulfonamides; Tumor Escape; Xanthones

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Proliferation; Cells, Cultured; Chickens; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Follicle Stimulating Hormone; Isoquinolines; Ovum; Protein Kinase C; Receptors, FSH; Sulfonamides; Tetradecanoylphorbol Acetate

Topics: Animals; Blotting, Western; Cell Proliferation; Cerebellar Neoplasms; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activators; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Isoquinolines; Kruppel-Like Transcription Factors; Medulloblastoma; Mice; Mice, Knockout; Morpholines; Patched Receptors; Patched-1 Receptor; Piperazines; Pituitary Adenylate Cyclase-Activating Polypeptide; Polymerase Chain Reaction; Protein Kinase Inhibitors; Purines; Pyrazoles; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I; Signal Transduction; Smoothened Receptor; Spheroids, Cellular; Sulfonamides; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Zinc Finger Protein GLI1

Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Biological Transport; Cell Line; Colforsin; Enzyme Inhibitors; Hypoglycemic Agents; Iodides; Isoquinolines; Male; Rats; Rats, Wistar; Ribonucleotides; Sulfonamides; Symporters; Thyroid Gland; Thyrotropin

Topics: Amino Acid Substitution; Animals; Antibodies; Antibody Specificity; Aquaporin 5; Calcimycin; Cell Line, Tumor; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Detergents; Humans; Isoproterenol; Isoquinolines; Male; Mice; Mice, Inbred ICR; Parotid Gland; Phosphorylation; Pilocarpine; Protein Kinase Inhibitors; Protein Transport; Salivary Glands; Signal Transduction; Submandibular Gland; Sulfonamides; Tetradecanoylphorbol Acetate; Threonine; Transfection

Topics: Animals; Anticonvulsants; Biophysics; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Fructose; gamma-Aminobutyric Acid; Humans; Isoquinolines; Larva; Membrane Potentials; Microinjections; Oocytes; Patch-Clamp Techniques; Protein Kinase Inhibitors; Protein Subunits; Receptors, GABA-A; Sulfonamides; Topiramate; Xenopus

Topics: Antigens, CD34; Blotting, Western; Bone Marrow Cells; CD4 Antigens; Cell Culture Techniques; Cell Line; Cell Nucleus; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; HIV Core Protein p24; HIV-1; Humans; Isoquinolines; Phosphorylation; Protein Kinase Inhibitors; Receptors, CCR5; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Stem Cells; Sulfonamides; Transcription, Genetic

Topics: Animals; Aquaporin 5; Blotting, Western; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Epithelium; Immunohistochemistry; Isoquinolines; Nasal Mucosa; Nerve Tissue Proteins; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Sulfonamides

Topics: Adrenergic beta-Agonists; Cells, Cultured; Colforsin; Gene Expression; GTP-Binding Protein alpha Subunits, Gs; Humans; Intraocular Pressure; Isoproterenol; Isoquinolines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Receptors, Adrenergic, beta-2; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sulfonamides; Trabecular Meshwork

Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adrenergic beta-1 Receptor Agonists; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Intracellular Signaling Peptides and Proteins; Isoproterenol; Isoquinolines; Membrane Proteins; Myocardium; Myocytes, Cardiac; Organ Culture Techniques; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Protein Transport; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adrenergic, beta-1; Signal Transduction; Sulfonamides; Xanthines

Topics: 1-Methyl-3-isobutylxanthine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Glioblastoma; Guanine Nucleotide Exchange Factors; Humans; Isoquinolines; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Rolipram; Shelterin Complex; Signal Transduction; Sulfonamides; Telomere-Binding Proteins; Theophylline

Topics: Adenylyl Cyclases; Animals; Biomimetic Materials; Carbon Monoxide; Carbon Monoxide Poisoning; Colforsin; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Guanine Nucleotide Exchange Factors; Hydroxybenzoates; Hydroxyl Radical; Isoquinolines; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides

Topics: Animals; Apoptosis; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Enzyme Inhibitors; Hepatocytes; Interleukin-10; Isoquinolines; Liver; Liver Transplantation; Macrophages; Male; Mice; Mice, Inbred C57BL; Necrosis; Peroxidase; Reperfusion Injury; Signal Transduction; Sulfonamides; Temperature

Topics: Adenylyl Cyclases; Animals; Bufonidae; Cell Nucleus; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Female; GTP-Binding Protein alpha Subunits, Gi-Go; In Vitro Oocyte Maturation Techniques; Intercellular Signaling Peptides and Proteins; Isoquinolines; Maturation-Promoting Factor; Oocytes; Ovarian Follicle; Peptides; Progesterone; Protein Kinase Inhibitors; Purines; Sulfonamides

Topics: Animals; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Activators; Guanylate Cyclase; Immunoblotting; Indazoles; Isoquinolines; Lung Diseases; Macrophages, Alveolar; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphoric Diester Hydrolases; Rats; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Sulfonamides

Topics: Animals; Benzhydryl Compounds; Carrier Proteins; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Humans; Iloprost; Intermediate-Conductance Calcium-Activated Potassium Channels; Isoquinolines; Male; Membrane Potentials; Mice; Modafinil; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NIH 3T3 Cells; Patch-Clamp Techniques; Peptide Fragments; Phosphorylation; Potassium Channel Blockers; Protein Kinase Inhibitors; Rats; Second Messenger Systems; Sulfonamides; Time Factors; Up-Regulation; Vasoconstriction; Vasodilator Agents

Topics: Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Hippocampus; Insect Proteins; Isoquinolines; Membrane Potential, Mitochondrial; Mice; Mitochondria; Neurites; Neurons; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I; RNA Interference; RNA, Small Interfering; Second Messenger Systems; Sulfonamides; Trans-Activators; Transcription Factors

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Colforsin; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclic AMP-Dependent Protein Kinases; Epithelial-Mesenchymal Transition; Hypoxia-Inducible Factor 1, alpha Subunit; Isoquinolines; Lung Neoplasms; Mice; RNA Interference; RNA, Small Interfering; Sulfonamides; Transforming Growth Factor beta1; Up-Regulation

Topics: Animals; Apoptosis; Calcium-Binding Proteins; Cells, Cultured; Colforsin; Diabetic Cardiomyopathies; Endoplasmic Reticulum Stress; Enzyme Activation; Exenatide; Glucagon-Like Peptide-1 Receptor; Glucose; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Hydrogen Peroxide; Hyperglycemia; Hypoglycemic Agents; Isoquinolines; Membrane Proteins; Myocytes, Cardiac; Oxidative Stress; Peptide Fragments; Peptides; Phosphorylation; Protein Kinase Inhibitors; Rats; Receptors, Glucagon; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sulfonamides; Thapsigargin; Transcription Factor CHOP; Tunicamycin; Unfolded Protein Response; Venoms

Topics: Abortifacient Agents, Nonsteroidal; Adenine; Adenylyl Cyclase Inhibitors; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colforsin; Cyclic AMP; Dinoprostone; DNA Helicases; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Humans; Isoquinolines; Liver Neoplasms; Nuclear Proteins; Pertussis Toxin; Phosphorylation; Protein Kinase Inhibitors; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; RNA Interference; RNA-Binding Proteins; RNA, Small Interfering; Smad2 Protein; Sulfonamides; Ubiquitination

Topics: Breast Neoplasms; Catalytic Domain; Chromatin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Estrogens; Female; Flavonoids; Histone Demethylases; Histones; Humans; Isoquinolines; MAP Kinase Signaling System; MCF-7 Cells; Methylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Sulfonamides; Transcription, Genetic; Tretinoin

Topics: 5' Untranslated Regions; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Fluoxetine; Gene Expression Regulation; Hemocytes; Humans; Isoquinolines; Models, Biological; Mytilus; Norepinephrine; Promoter Regions, Genetic; Propranolol; Receptors, Serotonin, 5-HT1; RNA, Messenger; Sequence Analysis, DNA; Serotonin; Serotonin Receptor Agonists; Signal Transduction; Sulfonamides; Up-Regulation

Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Isoquinolines; Muscle, Smooth; Pyloric Antrum; Rats; Rats, Wistar; Sulfonamides

Topics: Animals; Blood Platelets; Calcimycin; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Guanine Nucleotide Exchange Factors; HEK293 Cells; Humans; Isoquinolines; Phosphorylation; Platelet Activation; rap GTP-Binding Proteins; Rats; Sulfonamides

Topics: Animals; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Fura-2; In Vitro Techniques; Indoles; Isoquinolines; Kidney Tubules, Collecting; Maleimides; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Morpholines; Nephrons; Perfusion; Phorbol Esters; Protein Kinase C; Protein Kinase Inhibitors; Protein Transport; Pyrroles; Signal Transduction; Sulfonamides; TRPV Cation Channels

Topics: Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Stability; Gene Expression Regulation, Enzymologic; HEK293 Cells; Humans; Inflammation; Intracellular Signaling Peptides and Proteins; Isoquinolines; NF-kappa B; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2C; Proteolysis; Serine; Signal Transduction; Sulfonamides; Tumor Necrosis Factor-alpha; Ubiquitin

Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Benzazepines; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cytotoxicity, Immunologic; Dopamine Agonists; Dopamine Antagonists; Enzyme Activators; Gene Expression; Isoquinolines; Killer Cells, Natural; Mice, Inbred ICR; Phosphorylation; Protein Processing, Post-Translational; Quinpirole; Receptors, Dopamine D3; Receptors, Dopamine D4; Receptors, Dopamine D5; Second Messenger Systems; Sulfonamides

Topics: Animals; Bone Neoplasms; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Female; Isoquinolines; Pain; Pain Measurement; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides; Up-Regulation

Topics: Adjuvants, Immunologic; Animals; Astrocytes; Astrocytoma; Bucladesine; Cell Differentiation; Cell Line, Tumor; Colforsin; Glial Fibrillary Acidic Protein; Intracellular Membranes; Isoquinolines; Protein Kinase Inhibitors; Protein Transport; Rats; Receptors, Notch; Signal Transduction; Subcellular Fractions; Sulfonamides; Transcriptional Activation; Transfection; Up-Regulation

Topics: Colforsin; Cyclic AMP-Dependent Protein Kinases; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Indoles; Isoquinolines; Maleimides; Membrane Potential, Mitochondrial; Metalloporphyrins; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Reactive Oxygen Species; Sulfonamides; Tetradecanoylphorbol Acetate

Topics: Amino Acid Substitution; Animals; Bone Morphogenetic Protein 2; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; HEK293 Cells; Homeodomain Proteins; Humans; Isoquinolines; Mice; Osteoblasts; Phosphorylation; Protein Stability; Serine; Sulfonamides; Transcription Factors

Topics: Anilides; Colforsin; Cyclic AMP-Dependent Protein Kinases; Endothelial Cells; Exenatide; Gene Expression; Glucagon-Like Peptide-1 Receptor; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Isoquinolines; NADPH Oxidase 1; NADPH Oxidases; NF-kappa B; Peptides; Phosphorylation; Pioglitazone; PPAR gamma; Protein Kinase Inhibitors; Receptor Cross-Talk; Receptors, Glucagon; Signal Transduction; Sulfonamides; Thiazolidinediones; Vascular Cell Adhesion Molecule-1; Venoms

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Amidines; Amphetamine-Related Disorders; Animals; Benzophenanthridines; Central Nervous System Stimulants; Chronic Disease; Colforsin; Dextroamphetamine; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Isoquinolines; N-Methylaspartate; Oxidants; Protein Kinase Inhibitors; Rats, Wistar; Reflex; Spinal Cord; Sulfonamides; Urinary Retention; Urination; Valine

Topics: Animals; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Caspase 3; Cell Line, Tumor; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Ethanol; Humans; Isoquinolines; Mice; Neoplasm Proteins; Neuroblastoma; Neurons; Primary Cell Culture; Rats; RNA Interference; RNA, Small Interfering; Sulfonamides; Transcription, Genetic; Transfection

Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP-Dependent Protein Kinases; HeLa Cells; Humans; Immunoprecipitation; Isoquinolines; Mass Spectrometry; Phosphorylation; Protein Binding; Proteomics; rho-Associated Kinases; Sulfonamides

Topics: Androstadienes; Antibodies; Apoptosis; Arrestins; B-Lymphocytes; beta-Arrestins; Cell Differentiation; Cell Line, Tumor; Chromones; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; DNA Damage; DNA Repair; Gene Expression Regulation, Leukemic; Humans; Isoquinolines; Morpholines; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Sulfonamides; Thionucleotides; Tumor Suppressor Protein p53; Wortmannin

Topics: Binding Sites; Cell Line, Tumor; Chromatin Immunoprecipitation; Colforsin; Cyclic AMP Response Element-Binding Protein; HeLa Cells; Hep G2 Cells; Humans; Isoquinolines; Mutation; Neoplasms; Promoter Regions, Genetic; Protein Kinase Inhibitors; RNA Interference; RNA, Small Interfering; Sulfonamides; Thiolester Hydrolases; Transcriptional Activation; Ubiquitin Thiolesterase

Topics: Adenosine Triphosphate; Animals; Cell Line; Colforsin; Colon; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Eating; Glucagon-Like Peptide 1; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Isoquinolines; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Proglucagon; Proprotein Convertase 1; Protein Kinase Inhibitors; RNA, Messenger; Sulfonamides

Topics: Acetylcholine; Animals; Chromones; Colforsin; Curcumin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Embryonic Stem Cells; Gene Expression Regulation, Enzymologic; Isoquinolines; Leukemia Inhibitory Factor; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Signal Transduction; STAT3 Transcription Factor; Sulfonamides

Topics: Aquaporin 3; Cell Proliferation; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Humans; Isoquinolines; Signal Transduction; Sulfonamides; Up-Regulation

Topics: beta Catenin; Cell Fusion; Chorionic Gonadotropin, beta Subunit, Human; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Products, env; Glycoprotein Hormones, alpha Subunit; Humans; Isoquinolines; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pregnancy Proteins; Protein Kinase Inhibitors; RNA Interference; RNA, Small Interfering; Sulfonamides; Syndecan-1; Trophoblasts

Topics: Animals; Arginase; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Female; Gene Expression Regulation; Indomethacin; Interleukin-10; Isoquinolines; Macrophage Colony-Stimulating Factor; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Phenotype; Primary Cell Culture; Prostaglandin-Endoperoxide Synthases; Receptors, Cell Surface; Receptors, Immunologic; Signal Transduction; Sulfonamides

Topics: Adenosine Triphosphate; Animals; ATPase Inhibitory Protein; Binding Sites; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Assays; Gene Expression Regulation; Glycolysis; HCT116 Cells; Humans; Isoquinolines; Kinetics; Mice; Mitochondria, Heart; Mitochondrial Proton-Translocating ATPases; Models, Molecular; Myocardium; Oxidative Phosphorylation; Phosphorylation; Protein Binding; Proteins; Signal Transduction; Sulfonamides

Topics: Cell Line; Colforsin; Humans; Interleukin-11; Isoquinolines; Osteoblasts; Phosphorylation; Protein Kinase Inhibitors; Receptors, Thyrotropin; Signal Transduction; Sulfonamides; Thyrotropin; Up-Regulation

Topics: Adjuvants, Immunologic; Animals; Capsaicin; Cells, Cultured; Chromones; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Eicosanoids; Enzyme Inhibitors; Ganglia, Spinal; Isoquinolines; Male; Morpholines; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E, EP4 Subtype; Sensory Receptor Cells; Sensory System Agents; Signal Transduction; Sulfonamides; Time Factors

Topics: Age Factors; Animals; Animals, Newborn; beta Catenin; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; DEAD-box RNA Helicases; Gene Expression Regulation, Developmental; Hippocampus; Humans; Isoquinolines; Mice; Mice, Inbred BALB C; Neurites; Neurons; Protein Kinase Inhibitors; rac1 GTP-Binding Protein; RNA Helicases; Signal Transduction; Sulfonamides; Vasodilator Agents

Topics: Animals; Animals, Newborn; Cell Cycle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin B1; Cyclin D1; HEK293 Cells; Hippocampus; Humans; Isoquinolines; Neurons; Phosphorylation; Protein Phosphatase 2; Rats, Sprague-Dawley; Sulfonamides; tau Proteins

Topics: Animals; Blotting, Western; Butadienes; Cell Line, Tumor; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin D3; Enzyme Activation; Enzyme Inhibitors; Guanine Nucleotide Exchange Factors; Hydrazones; Isoquinolines; Isoxazoles; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Phosphorylation; Pituitary Gland; Proto-Oncogene Proteins B-raf; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sulfonamides

Topics: Action Potentials; Amphibian Proteins; Animals; Carbazoles; Colforsin; Excitatory Postsynaptic Potentials; Hair Cells, Ampulla; Isoquinolines; Miniature Postsynaptic Potentials; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Rana esculenta; Sulfonamides; Tissue Culture Techniques

Topics: Animals; Brain-Derived Neurotrophic Factor; Colforsin; CREB-Binding Protein; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Gene Expression Regulation; Germ-Free Life; Hippocampus; Humans; Infarction, Middle Cerebral Artery; Isoquinolines; Male; Neurons; Neuroprotective Agents; Platelet Aggregation Inhibitors; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sevoflurane; Sodium-Potassium-Exchanging ATPase; Sulfonamides

Topics: Colforsin; Female; Humans; Placenta; Pre-Eclampsia; Pregnancy; Renin; RNA, Messenger; Vitamin D; Vitamin D3 24-Hydroxylase