colforsin has been researched along with guanosine triphosphate in 298 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 153 (51.34) | 18.7374 |
| 1990's | 118 (39.60) | 18.2507 |
| 2000's | 24 (8.05) | 29.6817 |
| 2010's | 2 (0.67) | 24.3611 |
| 2020's | 1 (0.34) | 2.80 |
| Authors | Studies |
|---|---|
| Dénéréaz, N; Lemarchand-Béraud, T; Reymond, F | 1 |
| Childers, SR; Nijssen, PC; Sexton, T | 1 |
| Audette, M; Bouillon, M; Boulianne, R; Fortier, MA | 1 |
| Newman-Tancredi, A; Strange, PG; Wootton, R | 1 |
| Fahrenholz, F; Grünbaum, EG; Jans, DA; Luzius, H; Moritz, A; Rascher, W | 1 |
| Jakobs, KH; Ronzani, M; Wieland, T | 1 |
| Bangert, M; Beyer, T; Niroomand, F; Rauch, B | 1 |
| Asanuma, N; Nomura, H | 1 |
| Cushing, DJ; Makujina, SR; Mustafa, SJ; Sabouni, MH | 1 |
| Fujinami, H; Izawa, T; Komabayshi, T; Nakamura, T; Suda, K; Tsuboi, M | 1 |
| Fong, JC; Hong, SJ; Wang, FF | 1 |
| Dawson, G; McAtee, P | 1 |
| Akasu, T; Tokimasa, T | 1 |
| Deckmyn, H; Kienast, J; Van Geet, C; Vermylen, J; Wittevrongel, C | 1 |
| Osborne, NN | 1 |
| Keen, M; Kelly, E; MacDermot, J; Nobbs, P | 1 |
| Buja, LM; DeBeltz, D; Muntz, KH; Shaul, PW | 1 |
| Anderson, FL; Bristow, MR; Feldman, AM; Hershberger, RE; Kimball, JA; Wynn, JR | 1 |
| Farndale, RW; Martin, BR; Meikle, MC; Sandy, JR | 1 |
| Brown, LA | 1 |
| Mita, M; Nagahama, Y | 1 |
| Dattatreyamurty, B; Reichert, LE; Zhang, SB | 1 |
| Ozawa, H; Rasenick, MM | 2 |
| Arnold, R; Casiano, F; Childers, SR; Pacheco, M; Ward, SJ | 1 |
| Houslay, MD; Palmer, TM | 1 |
| Fujita, M; Hanai, H; Matsunaga, T; Natsukari, N | 1 |
| Bylund, DB; Jones, SB | 1 |
| Crasnier, M; Diez, E; Heller-Harrison, RA; Johnson, GL; Malbon, CC; Weiss, ER | 1 |
| Bellorin-Font, E; Lopez, C; Milanes, CL; Paz-Martinez, V; Pernalete, N; Starosta, R; Weisinger, J | 1 |
| Buckenmeyer, PJ; Dax, EM; Goldfarb, AH; Partilla, JS; Piñeyro, MA | 1 |
| Houslay, MD; Milligan, G; Strassheim, D | 1 |
| Bizzarri, C; Corda, D; D'Orazio, MC; Di Girolamo, M | 1 |
| Paris, S; Pouysségur, J | 1 |
| Hesslinger, B; McDonald, TF; Pelzer, D; Shuba, YM; Trautwein, W | 1 |
| Berry, RW; Redman, RS | 1 |
| Clark, RB; Dixon, RA; Friedman, J; Johnson, JA; Strader, CD | 1 |
| Brand, JG; Kare, MR; Katz, Y; Naim, M | 1 |
| Dufau, ML; Khanum, A | 2 |
| Fletcher, PW; Glennon, RA; Ismaiel, AM; Rydelek-Fitzgerald, L; Teitler, M | 1 |
| Kubotsu, K; Mori, S; Yamamoto, I; Yanagida, M | 1 |
| Anand-Srivastava, MB; Srivastava, AK | 2 |
| Scarpace, PJ | 1 |
| Fukuda, N; Hatano, M; Honda, M; Izumi, Y; Minato, M; Soma, M | 1 |
| Erlichman, J; Fleischer, N; Leiser, M; Litvin, Y | 1 |
| Lewis, DL; Luini, A; Weight, FF | 1 |
| Ishitoya, J; Takenawa, T | 1 |
| Cazenave, PA; Choquet, D; Korn, H; Primi, D; Sarthou, P | 1 |
| Downer, RG; Gole, JW; Orr, GL | 1 |
| Birnbaumer, L; Brown, AM; Codina, J; Imoto, Y; Reeves, JP; Yatani, A | 1 |
| Izawa, T; Komabayashi, T; Koshimizu, E; Shinoda, S; Suda, K; Tsuboi, M | 1 |
| Clayman, P; Goldberg, H; Skorecki, K | 1 |
| Asano, M; Masuzawa, K; Matsuda, T | 1 |
| Benishin, CG; Pang, PK; Zeng, YY | 1 |
| Blackmore, PF; Exton, JH; Johnson, EH; Krone, PK; Lynch, CJ; Wange, RL | 1 |
| Bushfield, M; Johnson, RA; Shoshani, I; Stübner, D; Yeung, SM | 1 |
| Fukuda, N; Hatano, M; Honda, M | 1 |
| Jakobs, KH; Wieland, T | 1 |
| Boyer, JL; Downes, CP; Evans, T; Harden, TK; Northup, JK; Waldo, GL | 1 |
| Brunelle, G; Coquil, JF | 1 |
| Gierschik, P; Jakobs, KH; Reithmann, C; Sidiropoulos, D; Werdan, K | 1 |
| Lancet, D; Mollner, S; Pfeuffer, E; Pfeuffer, T | 1 |
| Mazurkiewicz, D; Saggerson, ED | 1 |
| Attali, B; Saya, D; Vogel, Z | 1 |
| Jacobson, KL; Singh, JC; Watson, EL | 1 |
| Dolphin, AC; McGuirk, SM; Scott, RH | 1 |
| Hasegawa, T; Koshiura, R; Matsunaga, T; Miyamoto, K; Sanae, F; Satake, T; Takagi, K | 2 |
| Albinus, M; Armbruckner, L; Klein, S; Maier, R | 1 |
| Hintze, TH; Homcy, CJ; Nejima, J; Susanni, EE; Uemura, N; Vatner, DE; Vatner, SF | 1 |
| Björo, T; Gautvik, KM; Gordeladze, JO; Haug, E; Ostberg, BC; Torjesen, PA | 1 |
| Daval, JL; Deckert, J; Marangos, PJ; von Lubitz, DK | 1 |
| Hoffman, PL; Tabakoff, B; Valverius, P | 1 |
| Barak, Y; Lancet, D; Lazard, D | 1 |
| Saad, M; Strnad, CF; Wong, K | 1 |
| Ullrich, S; Wollheim, CB | 1 |
| Koch, T; Zenner, HP | 1 |
| Gregerman, RI; Kirkland, JL; Li, ZH; Lu, ZD; Piñeyro, MA | 1 |
| Duman, RS; Nestler, EJ; Tallman, JF | 1 |
| Battaglia, G; De Souza, EB; Webster, EL | 1 |
| García-Sáinz, JA; Hernández-Sotomayor, SM; Macías-Silva, M; Plebañski, M | 1 |
| Ramkumar, V; Stiles, GL | 2 |
| Johnston, LR; Wigham, T | 1 |
| Abens, J; Andell, S; Bartfai, T; Westlind-Danielsson, A | 1 |
| Boland, SR; Katz, MS; Schmidt, SJ | 1 |
| Dorflinger, LJ; Koch, BD; Schonbrunn, A | 1 |
| Bylund, DB; Ray-Prenger, C; Turner, JT | 1 |
| Schacht, J | 1 |
| Bell, JD; Brunton, LL | 2 |
| Lees, M; Smith, G; Turnberg, L; Warhurst, G | 1 |
| Bhoola, KD; Gadd, AL | 1 |
| Ahlijanian, MK; Cooper, DM; Perez-Reyes, E | 1 |
| Baba, A; Iwata, H; Nishiuchi, Y; Tatsuno, T; Uemura, A | 1 |
| Beiderman, B; Bourne, HR; Lopez, NG; Masters, SB; Miller, RT; Ramachandran, J; Sullivan, KA | 1 |
| Battaglia, G; Creese, I; Hess, EJ; Norman, AB | 2 |
| Lin, C; McGonigle, P; Molinoff, PB | 1 |
| Aktories, K; Willuweit, B | 1 |
| Oksenberg, D; Peroutka, SJ | 1 |
| Malbon, CC; Mangano, TJ; Rapiejko, PJ | 1 |
| Delavier-Klutchko, C; Durieu-Trautmann, O; Hoebeke, J; Strosberg, AD | 1 |
| Cooper, DM; Fossom, LH; Gill, DL; Owens, JR; Perez-Reyes, E; Yeung, SM | 1 |
| Mikami, K; Nishikawa, T; Strott, CA | 1 |
| Hayashi, Y; Kimura, T | 1 |
| Eyster, KM; Ottobre, JS; Stouffer, RL | 1 |
| Jagadeesh, G; Phan, NT; Sulakhe, PV | 1 |
| Kitamura, Y; Nomura, Y; Segawa, T | 1 |
| Birnbaumer, L; Caron, MG; Cerione, RA; Codina, J; Hildebrandt, JD; Iyengar, R; Lefkowitz, RJ; Mattera, R; Rojas, FJ; Sunyer, T | 1 |
| Beaufort, P; Camus, JC; Christophe, J; Clinet, M; Devos, C; Nokin, P; Robberecht, P; Schoenfeld, P; Waelbroeck, M | 1 |
| Neubig, RR; Szamraj, O | 1 |
| Insel, PA; Mahan, LC | 1 |
| Manning, DR; Nakada, MT; Woolkalis, MJ | 1 |
| Jakobs, KH; Watanabe, Y | 2 |
| Aublin, JL; Champion, S; Haye, B; Jacquemin, C; Lambert, B | 1 |
| Fain, JN; García-Sainz, JA; Mills, I | 1 |
| Agli, B; Giudicelli, Y; Lacasa, D | 2 |
| Anand-Srivastava, MB; Cantin, M | 2 |
| Bloom, AS; Hillard, CJ; Houslay, MD | 1 |
| Kawai, M; Kitamura, Y; Nomura, Y; Segawa, T | 1 |
| Gagne, B; Labrie, F; Poyet, P | 1 |
| Ho, RJ; Ruiz, J; Shi, QH | 1 |
| Anand-Srivastava, MB; Cantin, M; Srivastava, AK | 1 |
| Katada, T; Murakami, T; Yasuda, H | 1 |
| Nishikawa, T; Tamura, Y; Yoshida, A; Yoshida, S | 1 |
| Cooney, D; Dees, C; Hekman, M; Holzhöfer, A; Keenan, AK | 1 |
| Greiner, C; Jakobs, KH | 1 |
| Anholt, RR | 1 |
| Katada, T; Oinuma, M; Ui, M | 1 |
| Camus, JC; Christophe, J; De Neef, P; Gillard, M; Robberecht, P; Waelbroeck, M | 1 |
| Bilezikian, JP; Chow, YK; Steinberg, SF | 1 |
| Guillen, A; Haro, A; Municio, AM | 1 |
| Abramow, M; Cogan, E; Svoboda, M | 1 |
| Katada, T; Kusakabe, K; Oinuma, M; Ui, M | 1 |
| Estey, SJ; Mansour, TE | 1 |
| Ammon, HP; Kühn, M; Trier, JK | 1 |
| Nelson, CA; Seamon, KB | 2 |
| Arima, T; Nomura, Y; Swgawa, T | 1 |
| Anholt, RR; Sklar, PB; Snyder, SH | 1 |
| Fleming, JW; Strawbridge, RA; Watanabe, AM | 1 |
| Christophe, J; Dehaye, JP; Lambert, M; Mayer, R; Poloczek, P; Soukias, Y; van Bogaert, P; Winand, J | 1 |
| Gessa, GL; Olianas, MC; Onali, P; Petrenko, S | 1 |
| Ahlijanian, MK; Cooper, DM; Halford, MK | 1 |
| Giri, SN; Robison, TW | 1 |
| Brooker, G; Pedone, C | 1 |
| Olianas, MC; Onali, P | 1 |
| Jacobson, KL; Watson, EL | 1 |
| Cho, YH; Housman, A; Weiss, RM; Wheeler, MA | 1 |
| Gnegy, ME; Harrison, JK; Mickevicius, CK | 1 |
| Bégin-Heick, N | 1 |
| Gehlert, DR | 1 |
| Gierschik, P; Spiegel, AM | 1 |
| Durkin, JP; Franks, DJ; Whitfield, JF | 1 |
| Allende, JE; Anker, R; Olate, J | 1 |
| Anand-Srivastava, MB; Cantin, M; Johnson, RA; Picard, S | 1 |
| Dudai, Y; Zvi, S | 1 |
| Dudai, Y; Segal, D; Sher, B; Yovell, Y | 1 |
| Fletcher, P; Haley, BE; Hoyer, PB | 1 |
| Aakvaag, A; Torjesen, PA | 1 |
| Emoto, T; Hiraiwa, M; Kasai, K; Kuroda, H; Nakamura, T; Shimoda, S; Suzuki, Y | 1 |
| Asch, RH; Rojas, FJ | 1 |
| McNicholas, LF; Piascik, MT | 1 |
| Bulargina, TV; Khropov, YV; Severin, ES; Skurat, AV; Yurkova, MS | 1 |
| Addison, B; Babich, M; Piascik, MT | 1 |
| Bauer, S; Jakobs, KH; Watanabe, Y | 1 |
| Carney, JM; Chandler, MJ; Hornbrook, KR | 1 |
| Bauer, S; Horn, F; Jakobs, KH; Watanabe, Y | 1 |
| Aktories, K; Jakobs, KH; Schultz, G | 1 |
| Bokoch, GM; Gilman, AG; Katada, T; Smigel, MD; Ui, M | 1 |
| Heisler, S; Reisine, T | 1 |
| Ross, EM | 1 |
| Fain, JN; Fradin, M; Kasaian, M; Lee, HS; Litosch, I | 1 |
| Daly, JW; Seamon, KB | 1 |
| Martin, BR; Wong, SK | 1 |
| Goldman, ME; Kebabian, JW; Miyazaki, K | 1 |
| Bokoch, GM; Gilman, AG; Katada, T; Northup, JK; Ui, M | 1 |
| Abramowitz, J; Campbell, AR | 2 |
| Lipson, LG; Molloy, CT; Oldham, SB | 1 |
| Alouf, JE; Berthillier, G; Megret, F; Monneron, A | 1 |
| Caron, MG; Kilpatrick, BF; McDonald, WM; Sibley, DR | 1 |
| Makihata, J; Nomura, Y; Segawa, T | 1 |
| Birnbaumer, L; Desmier, M; Hanoune, J; Stengel, D | 1 |
| Ehrlich, A; Mansour, JM; Mansour, TE | 1 |
| Field, JB; Nielsen, TB; Totsuka, Y | 1 |
| Fain, JN; Hudson, TH | 1 |
| Fain, JN; Gárciá-Sáinz, JA; Mills, I; O'Donnell, CJ | 1 |
| Abrass, IB; Scarpace, PJ | 1 |
| Ferry, N; Hanoune, J; Insel, PA; Stengel, D | 1 |
| Biondi, C; Buzzi, M; Cavallaro, R; Fabbri, E; Ferretti, ME; Vesce, G | 1 |
| Cox, RH; Shi, QY | 1 |
| Aono, T; Hamada, S; Hamada, Y; Kamada, M; Nakaya, Y | 1 |
| Borea, PA; Danhof, M; IJzerman, AP; Mathôt, RA; van der Wenden, EM; Varani, K; von Frijtag Drabbe Künzel, JK | 1 |
| Berkich, DA; LaNoue, KF; Linden, J; Luthin, DR; Vannucci, SJ; Woodard, RL | 1 |
| Diederich, M; Eschenhagen, T; Kluge, SH; Magnussen, O; Mene, U; Müller, F; Schmitz, W; Scholz, H; Sent, U; Weil, J | 1 |
| Ammar, A; Butlen, D; Roseau, S | 1 |
| Mita, M; Nagahama, Y; Yoshikuni, M | 1 |
| Alvaro-Alonso, I; Arilla, E; Colás, B; Esteve, JP; Susini, C | 1 |
| Hall, IP; Kotlikoff, MI; Kume, H; Takagi, K; Washabau, RJ | 1 |
| Greenwood, MT; Panetta, R; Patel, YC; Srikant, CB; Warszynska, A | 1 |
| Bohl, J; Lemmer, B; Ohm, T; Schnecko, A; Witte, K | 1 |
| Clarke, W; Kung, HF; Kung, MP; Maayani, S; Zhuang, ZP | 1 |
| Houslay, MD; Livingstone, C; MacDonald, C; Willett, B | 1 |
| Jakobs, KH; Lenz, W; Sell, A; Van Koppen, CJ | 1 |
| Boss, GR; Pilz, RB; Quilliam, LA; Scheele, JS | 1 |
| Aguado, F; Bajo, AM; Guijarro, LG; Juarranz, MG; Prieto, JC; Rodriguez-Henche, N; Rodriguez-Pena, MS | 1 |
| Bell, GI; Kong, H; Mahan, LC; O'Carroll, AM; Raynor, K; Reisine, T; Yasuda, K | 1 |
| Johnson, GL; Russell, M; Winitz, S | 1 |
| Bockaert, J; Harris, B; Jouin, P; Le Nguyen, D; McClue, S; Varrault, A | 1 |
| McCook, EC; Seidler, FJ; Slotkin, TA | 1 |
| Anand-Srivastava, MB | 1 |
| Bell, GI; Kong, H; Moe, ST; Portoghese, PS; Raynor, K; Reisine, T; Yasuda, K | 1 |
| Hayashi, H; Hong, RB; Ikegaya, T; Kaneko, M; Kobayashi, A; Masuda, H; Yamazaki, N | 1 |
| Henley, JM; Kirkham, DM | 1 |
| Etgen, AM; Makman, MH; Morris, SA; Ungar, S | 1 |
| Hartzell, HC; Parsons, TD | 1 |
| Bourne, HR; Markby, DW; Onrust, R | 1 |
| Koshland, DE; Morimoto, BH | 1 |
| Budnik, LT; Mukhopadhyay, AK | 1 |
| Gilman, AG; Iñiguez-Lluhi, JA; Taussig, R | 1 |
| Crain, SM; Cruciani, RA; Dvorkin, B; Makman, MH; Morris, SA | 1 |
| Cortinovis, C; Klimek, F; Nogueira, E | 1 |
| Domanska-Janik, K; Pyłowa, S; Zalewska, T | 1 |
| Consiglio, E; Di Jeso, B; Formisano, S; Laviola, L; Liguoro, D | 1 |
| Cussac, D; Enjalbert, A; Kordon, C; Saltarelli, D | 1 |
| Hall, JL; Hamilton, CD; Roth, DA; Stanley, WC; White, CD | 1 |
| Andell, S; Bartfai, T; Berthold, M; Bourne, J; Kask, K; Langel, U | 1 |
| Kashiwayanagi, M; Okamoto, K; Tokumitsu, Y | 1 |
| Helms, JB; Kneusel, RE; Nickel, W; Wieland, FT | 1 |
| Calvo, JR; Carrero, I; Guijarro, LG; Pozo, D; Prieto, JC; Segura, JJ | 1 |
| Benzakour, O; Kakkar, VV; Kanse, SM; Kanthou, C | 1 |
| Hazeki, K; Hazeki, O; Katada, T; Suzuki, T; Ui, M | 1 |
| Delhase, M; Hooghe-Peters, E; Rajas, F; Robberecht, P; Svoboda, M; Trouillas, J; Vertongen, P | 1 |
| Burnstock, G; Höpker, VH; Saffrey, MJ | 1 |
| Neu, JM; Niles, LP; Tenn, CC | 1 |
| Reithmann, C; von Scheidt, W; Werdan, K | 1 |
| Grünewald, S; Michel, H; Reiländer, H | 1 |
| Clark, JB; Leung, FC; Saggerson, ED | 1 |
| Gysbers, JW; Rathbone, MP | 1 |
| Babenko, A; Vassort, G | 1 |
| Bick, RJ; Buja, LM; King, TW; LeMaistre, A; Liao, JP; McMillin, JB | 1 |
| Seidler, FJ; Slotkin, TA; Zeiders, JL | 1 |
| Du, F; Quaegebeur, JM; Sun, LS | 1 |
| Chen, Y; Harry, A; Iyengar, R; Magnusson, R; Weng, G | 1 |
| Andrés, A; Cubero, A; Fernández, M; Gonzalez-Calero, G; Ros, M; Ruiz, A; Sanz, JM | 1 |
| Niles, LP; Tenn, CC | 1 |
| Busto, R; Carmena, MJ; Carrero, I; Guijarro, LG; Juarranz, MG; Prieto, JC | 1 |
| Bouet-Alard, R; Legrand, C; Limon-Boulez, I; Maltier, JP; Mhaouty-Kodja, S | 1 |
| Bourne, HR | 1 |
| Komatsu, M; Noda, M; Sharp, GW | 1 |
| Barritt, GJ; Fernando, KC; Gregory, RB | 1 |
| Dunne, MJ; James, RF; Sharp, GW; Straub, SG | 1 |
| Cohen-Tannoudji, J; Coudouel, N; Lécrivain, JL; Legrand, C; Maltier, JP; Robin, MT | 1 |
| McCook, EC; Seidler, FJ; Slotkin, TA; Zhang, J | 1 |
| Järv, J; Karelson, E; Lember, J; Rosenthal, K | 1 |
| Chen, C; Eguchi, T; Ishida, H; Ishikawa, Y; Skowronski, MT | 1 |
| Emala, CW; Hirshman, CA; Kuhl, JS; Levitsky, HI; Lindeman, KS | 1 |
| Anand-Srivastava, MB; de Champlain, J; Marcil, J | 1 |
| Nikaido, SS; Takahashi, JS | 1 |
| Böl, GF; Dahmen, N; Ferdinand, K; Hiemke, C; Pauly, T; Szegedi, A; Wetzel, H | 1 |
| Coronas, V; Jourdan, F; Krantic, S; Moyse, E | 1 |
| Makhlouf, GM; Murthy, KS | 1 |
| Allouche, S; Hasbi, A; Homburger, V; Jauzac, P; Polastron, J | 1 |
| Bourin, MC; Defer, N; Espinasse, I; Giudicelli, JF; Hanoune, J; Heimburger, M; Iourgenko, V; Mercadier, JJ; Michel, JB; Pussard, E; Richer, C; Samson, F | 1 |
| Ambrosini, A; Barassi, A; Racagni, G; Sturani, E; Tininini, S; Zippel, R | 1 |
| Bailly, JM; Deschamps, F; Fillion, G; Grimaldi, B; Kochanek, M; Lambrozo, J; Massot, O | 1 |
| Grammatopoulos, D; Hillhouse, EW; Karteris, E; Randeva, H | 1 |
| Bilyeu, JD; Patel, TB; Scholich, K; Wittpoth, C | 1 |
| Dremier, S; Dumont, JE; Roger, PP; Van Keymeulen, A | 1 |
| Bourin, MC; Crozatier, B; Germack, R; León-Velarde, F; Mohammadi, K; Richalet, JP | 1 |
| Bahia, DS; Cavalli, A; Hoffmann, M; Massotte, D; Milligan, G; Moon, HE | 1 |
| Banchelli, G; Matucci, R; Pirisino, R; Raimondi, L; Stillitano, F | 1 |
| Hildebrandt, JD; Lanier, SM; Ribas, C; Sato, M; Takesono, A | 1 |
| Emala, CW; Gogarten, W; Hirshman, CA; Lindeman, KS | 1 |
| Burridge, K; Ellerbroek, SM; Wennerberg, K | 1 |
| Anderson, CM; Kilts, CD; Lachowicz, JE; Leonard, SK; Mailman, RB; Schulz, DW | 1 |
| Krishnamurthy, G; Smith, D; Tawa, G; Wang, Y; Young, KH | 1 |
| Eichinger, D; Frederick, J | 1 |
| Fukuhara, S; Kangawa, K; Mochizuki, N; Saito, Y; Sakurai, A; Sano, H; Somekawa, S; Takakura, N; Yamagishi, A | 1 |
| Avdeeva, EV; Gur'ianov, IA; Shpakov, AO; Vlasov, GP; Vorob'ev, VI | 1 |
| Dietl, J; Engelhardt, S; Frambach, T; Freund, S; Lohse, MJ; Müller, T; Sütterlin, M | 1 |
| de Ligt, RA; IJzerman, AP; Leurs, R; Lorenzen, A; Rivkees, SA | 1 |
| Misra, UK; Pizzo, SV | 1 |
| Doughty, MB; Gille, A; Guo, J; Lushington, GH; Mou, TC; Seifert, R | 1 |
| Fujita, T; Oka, M; Wada, M; Wu, Q; Yamamoto, A | 1 |
| Kuznetsova, LA; Pertseva, MN; Plesneva, SA; Shpakov, AO | 1 |
| Geduhn, J; Gille, A; Göttle, M; Höcherl, K; König, B; Seifert, R | 1 |
| Gille, A; Hübner, M; Mou, TC; Pinto, C; Richter, M; Seifert, R; Sprang, SR | 1 |
| Fukuhara, S; Kunimoto, S; Mochizuki, N; Noda, K; Yoshimura, M; Zhang, J | 1 |
| Chistiakova, OV; Derkach, KV; Shpakov, AO; Shpakova, EA; Tarasenko, II; Vlasov, GP | 1 |
| Bondar, AN; Dessauer, CW; Dreier, B; Khanppnavar, B; Korkhov, VM; Lavriha, P; Lazaratos, M; Li, Y; Mehta, V; Mohammed, I; Plückthun, A; Qi, C; Schaefer, JV | 1 |
1 review(s) available for colforsin and guanosine triphosphate
| Article | Year |
|---|---|
Regulation of hormone receptors and adenylyl cyclases by guanine nucleotide binding N proteins.
Topics: Adenylyl Cyclases; Animals; Colforsin; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Hormones; Humans; Hydrolysis; Kinetics; Magnesium; Molecular Weight; Nucleotides; Protein Conformation; Rats; Receptors, Cell Surface | 1985 |
297 other study(ies) available for colforsin and guanosine triphosphate
| Article | Year |
|---|---|
Thyrotropin action is impaired in the thyroid gland of old rats.
Topics: Adenylyl Cyclases; Aging; Animals; Cell Membrane; Colforsin; Cyclic AMP; Guanosine Triphosphate; Male; Rats; Rats, Inbred Strains; Thyroid Gland; Thyroid Hormones; Thyrotropin | 1992 |
Opioid-inhibited adenylyl cyclase in rat brain membranes: lack of correlation with high-affinity opioid receptor binding sites.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Brain; Cell Membrane; Colforsin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine Triphosphate; Male; Naloxone; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sodium; Sodium Chloride; Sodium Fluoride | 1992 |
Biphasic effect of cAMP-elevating agents on ICAM-1 expression stimulated by retinoic acid and interferon gamma.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Adhesion Molecules; Cholera Toxin; Colforsin; Cyclic AMP; Cytosol; Gene Expression Regulation, Neoplastic; Glioma; Guanosine Triphosphate; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Kinetics; Pertussis Toxin; Recombinant Proteins; Stimulation, Chemical; Time Factors; Tretinoin; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
High-level stable expression of recombinant 5-HT1A 5-hydroxytryptamine receptors in Chinese hamster ovary cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Binding, Competitive; Blotting, Northern; Cattle; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Gene Expression; Guanosine Triphosphate; Hippocampus; Humans; Receptors, Serotonin; Recombinant Proteins; Tetrahydronaphthalenes; Transfection | 1992 |
A low affinity vasopressin V2-receptor in inherited nephrogenic diabetes insipidus.
Topics: Adenylyl Cyclases; Animals; Arginine Vasopressin; Binding, Competitive; Cell Membrane; Colforsin; Diabetes Insipidus; Dogs; GTP-Binding Proteins; Guanosine Triphosphate; Male; Radioligand Assay; Receptors, Angiotensin; Receptors, Vasopressin; Sodium Fluoride | 1992 |
Stimulation and inhibition of human platelet adenylylcyclase by thiophosphorylated transducin beta gamma-subunits.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Animals; Blood Platelets; Cattle; Colforsin; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Kinetics; Macromolecular Substances; Thionucleotides; Transducin | 1992 |
Reduced adenylyl cyclase inhibition by carbachol and GTP during acute myocardial ischaemia.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carbachol; Colforsin; Coronary Disease; Dogs; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Receptors, Muscarinic | 1992 |
Cytochemical localization of adenylate cyclase activity in rat olfactory cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Cilia; Colforsin; Cyclic AMP; Dendrites; Guanosine Triphosphate; Histocytochemistry; Microscopy, Electron; Olfactory Mucosa; Rats; Rats, Inbred Strains; Signal Transduction; Strontium | 1991 |
Inhibition of adenylate cyclase attenuates adenosine receptor-mediated relaxation in coronary artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Colforsin; Coronary Vessels; Cyclic AMP; Dideoxyadenosine; Dilazep; Guanosine Triphosphate; In Vitro Techniques; Muscle Relaxation; Receptors, Purinergic; Sodium Fluoride; Swine; Vasodilator Agents | 1991 |
In vivo adaptive control of beta-receptors and adenylate cyclase during short-term heat exposure in rat parotid glands.
Topics: Adaptation, Physiological; Adenylyl Cyclases; Animals; Chlorides; Colforsin; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Hot Temperature; Isoproterenol; Male; Manganese; Manganese Compounds; Membranes; Norepinephrine; Parotid Gland; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Synaptic Transmission; Time Factors | 1991 |
Somatostatin inhibits pepsinogen secretion via a cyclic AMP-independent pathway.
Topics: Adenylyl Cyclases; Animals; Bethanechol; Bethanechol Compounds; Cell Membrane; Colforsin; Cyclic AMP; Esophagus; Gastric Mucosa; Guanosine Triphosphate; Pepsinogens; Rana catesbeiana; Somatostatin | 1991 |
Phospholipase C activity in NCB-20 cells is inhibited by protein kinase A-mediated phosphorylation of low molecular mass GTP-binding proteins.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Brain; Cell Line; Cholera Toxin; Colforsin; Cricetinae; Embryo, Mammalian; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hybrid Cells; Inositol Phosphates; Kinetics; Molecular Weight; Neuroblastoma; Phosphorylation; Protein Kinases; Thionucleotides; Type C Phospholipases | 1990 |
Cyclic AMP regulates an inward rectifying sodium-potassium current in dissociated bull-frog sympathetic neurones.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Membrane Potentials; Neurons; Potassium; Rana catesbeiana; Sodium; Sympathetic Nervous System; Thionucleotides; Time Factors | 1990 |
Guanine nucleotide-dependent inhibition of phospholipase C in human endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Aluminum; Aluminum Chloride; Aluminum Compounds; Calcimycin; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Deoxycholic Acid; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Inositol Phosphates; Kinetics; Sodium Fluoride; Thionucleotides; Thrombin; Type C Phospholipases; Umbilical Veins | 1990 |
Effects of GTP, forskolin, sodium fluoride, serotonin, dopamine, and carbachol on adenylate cyclase in Teleost retina.
Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Atropine; Carbachol; Colforsin; Cyclic AMP; Dopamine; Drug Synergism; Fishes; GTP-Binding Proteins; Guanosine Triphosphate; Pertussis Toxin; Retina; Serotonin; Sodium Fluoride; Tetrahydronaphthalenes; Virulence Factors, Bordetella | 1990 |
NaF and guanine nucleotides modulate adenylate cyclase activity in NG108-15 cells by interacting with both Gs and Gi.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cell Membrane; Colforsin; Enzyme Activation; Epoprostenol; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Iloprost; Mice; Morphine; Nervous System Neoplasms; Neuroblastoma; Pertussis Toxin; Sodium Fluoride; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Ontogeny of the adenylate cyclase system in the pulmonary vascular smooth muscle of the fetal lamb.
Topics: Adenylyl Cyclases; Aging; Animals; Cell Membrane; Colforsin; Cyclic AMP; Embryonic and Fetal Development; Female; Fetus; Guanosine Triphosphate; Isoproterenol; Muscle Development; Muscle, Smooth, Vascular; Pregnancy; Pulmonary Circulation; Receptors, Adrenergic, beta; Sheep; Sodium Fluoride; Stimulation, Chemical | 1991 |
Mr 40,000 and Mr 39,000 pertussis toxin substrates are increased in surgically denervated dog ventricular myocardium.
Topics: 5'-Nucleotidase; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Catecholamines; Colforsin; Dogs; Female; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; In Vitro Techniques; Male; Manganese; Membranes; Muscle Denervation; Myocardium; Pertussis Toxin; Phosphorus Radioisotopes; Receptors, Adrenergic, beta; Virulence Factors, Bordetella | 1991 |
Leukotriene B4 increases intracellular calcium concentration and phosphoinositide metabolism in mouse osteoblasts via cyclic adenosine 3',5'-monophosphate-independent pathways.
Topics: 1-Methyl-3-isobutylxanthine; 1-Phosphatidylinositol 4-Kinase; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Leukotriene B4; Mice; Osteoblasts; Parathyroid Hormone; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphotransferases | 1991 |
Influence of streptozotocin-induced diabetes on adenylate cyclase activity in cultured type II pneumocytes.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Deoxyglucose; Diabetes Mellitus, Experimental; Guanosine Triphosphate; Insulin; Isoproterenol; Lung; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Receptor, Insulin; Sodium Fluoride; Streptozocin | 1991 |
Involvement of G-proteins and adenylate cyclase in the action of gonad-stimulating substance on starfish ovarian follicle cells.
Topics: Adenine; Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dithiothreitol; Ethylmaleimide; Female; GTP-Binding Proteins; Guanosine Triphosphate; In Vitro Techniques; Meiosis; Membrane Proteins; Membranes; Molecular Weight; Neurosecretory Systems; Ovary; Sodium Fluoride; Starfish | 1991 |
Differential roles of high and low affinity guanosine 5'-triphosphate binding sites in the regulation of follicle-stimulating hormone binding to receptor and signal transduction in bovine calf testis membranes.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Cattle; Cell Membrane; Cholera Toxin; Colforsin; Enzyme Activation; Ethylmaleimide; Follicle Stimulating Hormone; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Male; Receptors, FSH; Signal Transduction; Testis | 1991 |
Chronic electroconvulsive treatment augments coupling of the GTP-binding protein Gs to the catalytic moiety of adenylyl cyclase in a manner similar to that seen with chronic antidepressant drugs.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Affinity Labels; Amitriptyline; Animals; Antidepressive Agents; Azides; Cerebral Cortex; Colforsin; Electroshock; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Iprindole; Kinetics; Male; Photochemistry; Rats; Rats, Inbred Strains; Sodium Fluoride; Synaptic Membranes | 1991 |
Aminoalkylindoles: actions on specific G-protein-linked receptors.
Topics: Adenylyl Cyclase Inhibitors; Analgesics; Animals; Brain; Colforsin; GTP-Binding Proteins; Guanosine Triphosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Male; Mice; Muscle Contraction; Receptors, Drug; Vas Deferens | 1991 |
Determination of G-protein levels, ADP-ribosylation by cholera and pertussis toxins and the regulation of adenylyl cyclase activity in liver plasma membranes from lean and genetically diabetic (db/db) mice.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Male; Mice; Mice, Inbred C57BL; Pertussis Toxin; Virulence Factors, Bordetella | 1991 |
Synergistic activation of brain adenylate cyclase by calmodulin, and either GTP or catecholamines including dopamine.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Calmodulin; Catecholamines; Cerebral Cortex; Colforsin; Corpus Striatum; Dopamine; Drug Synergism; Egtazic Acid; Enzyme Activation; Guanosine Triphosphate; Intracellular Membranes; Isoproterenol; Kinetics; Rats; Synaptosomes | 1990 |
Effects of alpha 2-adrenergic agonist preincubation on subsequent forskolin-stimulated adenylate cyclase activity and [3H]forskolin binding in membranes from HT29 cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Cell Membrane; Colforsin; Colonic Neoplasms; Cyclic AMP; Guanosine Triphosphate; Humans; Pertussis Toxin; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Rhodopsin expressed in Chinese hamster ovary cells regulates adenylyl cyclase activity.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cell Line; Colforsin; Cricetinae; DNA; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Light; Ovary; Pertussis Toxin; Phosphatidylinositols; Recombinant Proteins; Retinal Pigments; Retinaldehyde; Rhodopsin; Thionucleotides; Thrombin; Transfection; Virulence Factors, Bordetella | 1990 |
Effect of acidosis on PTH-dependent renal adenylate cyclase in phosphorus deprivation: role of G proteins.
Topics: Acidosis; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Ammonium Chloride; Animals; Cholera Toxin; Colforsin; Dogs; Ethylmaleimide; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kidney; Magnesium; Manganese; Membrane Proteins; Parathyroid Hormone; Pertussis Toxin; Phosphorus; Sodium Fluoride; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Endurance training, not acute exercise, differentially alters beta-receptors and cyclase in skeletal fiber types.
Topics: Adenylyl Cyclases; Animals; Colforsin; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Muscles; Organ Specificity; Physical Conditioning, Animal; Physical Exertion; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Reference Values; Sodium Fluoride; Succinate Cytochrome c Oxidoreductase | 1990 |
Diabetes abolishes the GTP-dependent, but not the receptor-dependent inhibitory function of the inhibitory guanine-nucleotide-binding regulatory protein (Gi) on adipocyte adenylate cyclase activity.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Blotting, Western; Cell Membrane; Colforsin; Diabetes Mellitus, Experimental; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Niacin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Purinergic | 1990 |
Evidence that a guanine nucleotide-binding protein linked to a muscarinic receptor inhibits directly phospholipase C.
Topics: Alkaloids; Animals; Atropine; Calcimycin; Calcium; Carbachol; Cell Line; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cytosol; GTP-Binding Proteins; Guanosine Triphosphate; Inositol Phosphates; Kinetics; Norepinephrine; Pertussis Toxin; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Staurosporine; Type C Phospholipases; Virulence Factors, Bordetella | 1990 |
Guanosine 5'-O-(3-thiotriphosphate) and guanosine 5'-O-(2-thiodiphosphate) activate G proteins and potentiate fibroblast growth factor-induced DNA synthesis in hamster fibroblasts.
Topics: Adenylate Cyclase Toxin; Animals; Cell Line; Colforsin; Cricetinae; Cricetulus; DNA; DNA Replication; Fibroblast Growth Factors; Fibroblasts; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Inositol Phosphates; Insulin; Kinetics; Pertussis Toxin; Phosphatidylinositols; Potassium Chloride; Recombinant Proteins; Sodium Chloride; Thionucleotides; Thrombin; Type C Phospholipases; Virulence Factors, Bordetella | 1990 |
Whole-cell calcium current in guinea-pig ventricular myocytes dialysed with guanine nucleotides.
Topics: Action Potentials; Adenylyl Cyclases; Animals; Calcium; Calcium Channels; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Guinea Pigs; Heart Ventricles; Ion Channel Gating; Isoproterenol; Myocardium; Phosphorylation; Signal Transduction | 1990 |
Alpha-bag cell peptide inhibits bag cell adenylate cyclase via a GTP-dependent mechanism.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Aplysia; Colforsin; Diterpenes; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Invertebrate Hormones; Neurosecretory Systems; Peptide Fragments; Pertussis Toxin; Second Messenger Systems; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Identification of a specific domain in the beta-adrenergic receptor required for phorbol ester-induced inhibition of catecholamine-stimulated adenylyl cyclase.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cells, Cultured; Colforsin; Epinephrine; GTP-Binding Proteins; Guanosine Triphosphate; L Cells; Magnesium; Mice; Pertussis Toxin; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Nonreceptor-mediated responses of adenylate cyclase in membranes from liver, muscle, and white and brown adipose tissue of obese (fa/fa) and lean (Fa/) Zucker rats.
Topics: Adenylyl Cyclases; Adipose Tissue; Adipose Tissue, Brown; Animals; Body Weight; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Liver; Muscles; Norepinephrine; Obesity; Organ Size; Rats; Rats, Zucker; Receptors, Adrenergic, beta | 1990 |
A cAMP independent inhibitory action of high doses of forskolin in rat Leydig cells.
Topics: Adenylyl Cyclases; Animals; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Diterpenes; Guanosine Triphosphate; Leydig Cells; Male; Pregnenolone; Rats; Rats, Inbred Strains; Testosterone | 1990 |
NAN-190: agonist and antagonist interactions with brain 5-HT1A receptors.
Topics: Adenylyl Cyclases; Adenylyl Imidodiphosphate; Animals; Brain; Colforsin; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; In Vitro Techniques; Male; Membranes; Piperazines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists | 1990 |
Characterization of detergent dispersed cytidylate cyclase of rat brain.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Brain; Cell Membrane; Colforsin; Cytidine Triphosphate; Detergents; Guanosine Triphosphate; Hydrogen-Ion Concentration; Lanthanum; Lyases; Magnesium; Male; Manganese; Mice; Phosphorus-Oxygen Lyases; Rats; Rats, Inbred Strains; Solubility; Substrate Specificity | 1990 |
Modulation of adenylate cyclase activity by Ca2+, phospholipid-dependent protein kinase in rat brain striatum.
Topics: Adenylyl Cyclases; Animals; Brain; Cell Membrane; Colforsin; Guanosine Triphosphate; Protein Kinase C; Rats; Rats, Inbred Strains | 1990 |
Forskolin activation of adenylate cyclase in rat myocardium with age: effects of guanine nucleotide analogs.
Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Female; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; Myocardium; Rats; Rats, Inbred F344; Thionucleotides | 1990 |
Adenylate cyclase activities of vascular smooth muscle in early and established DOCA/salt hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Calmodulin; Colforsin; Desoxycorticosterone; Guanosine Triphosphate; Hypertension; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Saline Solution, Hypertonic | 1990 |
Somatostatin inhibits corticotropin-releasing factor-stimulated adrenocorticotropin release, adenylate cyclase, and activation of adenosine 3',5'-monophosphate-dependent protein kinase isoenzymes in AtT20 cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Cell Line; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoenzymes; Mice; Pituitary Neoplasms; Protein Kinases; Somatostatin; Thionucleotides | 1986 |
A guanine nucleotide-binding protein mediates the inhibition of voltage-dependent calcium current by somatostatin in a pituitary cell line.
Topics: Adenylate Cyclase Toxin; Calcium; Cell Line; Colforsin; Cyclic AMP; Electric Conductivity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Ion Channels; Membrane Potentials; Nifedipine; Pertussis Toxin; Pituitary Gland; Receptors, Neurotransmitter; Receptors, Somatostatin; Somatostatin; Thionucleotides; Virulence Factors, Bordetella | 1986 |
Potentiation of PGE1-induced increase in cyclic AMP by chemotactic peptide and Ca2+ ionophore through calmodulin-dependent processes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alprostadil; Animals; Calcimycin; Calmodulin; Colforsin; Cyclic AMP; Drug Synergism; Female; Guanosine Triphosphate; Guinea Pigs; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandin Antagonists; Sulfonamides; Tetradecanoylphorbol Acetate | 1987 |
Cyclic AMP-modulated potassium channels in murine B cells and their precursors.
Topics: Animals; B-Lymphocytes; Calcium; Cell Differentiation; Colforsin; Cyclic AMP; Guanosine Triphosphate; Immunocompetence; Ion Channels; Lipopolysaccharides; Mice; Potassium | 1987 |
Forskolin-insensitive adenylate cyclase in cultured cells of Choristoneura fumiferana (Insecta).
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cell Line; Colforsin; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Lepidoptera; Octopamine; Sodium Fluoride | 1987 |
A G protein directly regulates mammalian cardiac calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart; Ion Channels; Isoproterenol; Leupeptins; Membrane Potentials; Phosphorylation; Thionucleotides; Ventricular Function | 1987 |
Possible mechanism of regulating adenylate cyclase activity in adipocyte membranes from exercise-trained male rats.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cholera Toxin; Colforsin; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1988 |
Mechanism of Li inhibition of vasopressin-sensitive adenylate cyclase in cultured renal epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Animals; Biological Transport; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Epithelium; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kidney; Kinetics; Lithium; Magnesium; Sodium Fluoride; Swine; Vasopressins | 1988 |
Role of stimulatory GTP-binding protein (Gs) in reduced beta-adrenoceptor coupling in the femoral artery of spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Antagonists; Animals; Bucladesine; Cholera Toxin; Colforsin; Femoral Artery; GTP-Binding Proteins; Guanosine Triphosphate; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Timolol | 1988 |
Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. II. Studies with guanosine 5'-(gamma)triphosphate.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Arteries; Bucladesine; Calcium; Calcium Channels; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Kinetics; Male; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Rats; Rats, Inbred Strains; Thionucleotides; Vasoconstriction | 1989 |
Guanine nucleotide binding regulatory proteins and adenylate cyclase in livers of streptozotocin- and BB/Wor-diabetic rats. Immunodetection of Gs and Gi with antisera prepared against synthetic peptides.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aluminum; Angiotensin II; Animals; Catalysis; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Enzyme Activation; Fluorine; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Immune Sera; Injections, Intraperitoneal; Liver; Male; Peptide Fragments; Pertussis Toxin; Rats; Rats, Inbred BB; Rats, Inbred Strains; Virulence Factors, Bordetella | 1989 |
Cation and structural requirements for P site-mediated inhibition of adenylate cyclase.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Brain; Colforsin; Deoxyadenine Nucleotides; Dideoxyadenosine; Dideoxynucleosides; Egtazic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Magnesium; Manganese; Receptors, Purinergic; Structure-Activity Relationship; Thionucleotides | 1989 |
Role of the calcium-calmodulin system in the adenylate cyclase activity of vascular smooth muscle.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Calcimycin; Calcium; Calmodulin; Colforsin; Edetic Acid; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Trifluoperazine | 1989 |
Evidence for receptor-regulated phosphotransfer reactions involved in activation of the adenylate cyclase inhibitory G protein in human platelet membranes.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Blood Platelets; Cell Membrane; Colforsin; Enzyme Activation; Epinephrine; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Sodium Chloride | 1989 |
Modification of AlF-4- and receptor-stimulated phospholipase C activity by G-protein beta gamma subunits.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Aluminum; Aluminum Compounds; Animals; Brain; Cattle; Colforsin; Enzyme Activation; Erythrocyte Membrane; Female; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Macromolecular Substances; Placenta; Pregnancy; Receptors, Purinergic; Thionucleotides; Turkeys; Type C Phospholipases | 1989 |
Adenylate cyclase of platelets from spontaneously hypertensive rats: reduction of the inhibition by GTP.
Topics: Adenylyl Cyclases; Animals; Blood Platelets; Cell Membrane; Colforsin; Egtazic Acid; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY | 1989 |
Mechanism of noradrenaline-induced heterologous desensitization of adenylate cyclase stimulation in rat heart muscle cells: increase in the level of inhibitory G-protein alpha-subunits.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cells, Cultured; Colforsin; GTP-Binding Proteins; Guanosine Triphosphate; Heart; Immunoblotting; Myocardium; Norepinephrine; Pertussis Toxin; Rats; Virulence Factors, Bordetella | 1989 |
Olfactory adenylyl cyclase. Identification and purification of a novel enzyme form.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Antibodies, Monoclonal; Blotting, Western; Brain; Calcium; Calmodulin; Chromatography, Affinity; Cilia; Colforsin; Epithelium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Molecular Weight; Olfactory Mucosa; Rats; Rats, Inbred Strains; Thionucleotides | 1989 |
Coupling of the stimulatory GTP-binding protein Gs to rat synaptic membrane adenylate cyclase is enhanced subsequent to chronic antidepressant treatment.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Antidepressive Agents, Tricyclic; Cerebral Cortex; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Medulla; Liver; Male; Rats; Rats, Inbred Strains; Signal Transduction; Synaptic Membranes | 1989 |
Inhibition of adenylate cyclase in rat brain synaptosomal membranes by GTP and phenylisopropyladenosine is enhanced in hypothyroidism.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Hypothyroidism; Phenylisopropyladenosine; Rats; Receptors, Purinergic; Sodium; Synaptosomes; Xanthines | 1989 |
Kappa-opiate agonists inhibit adenylate cyclase and produce heterologous desensitization in rat spinal cord.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Benzomorphans; Cell Membrane; Cells, Cultured; Colforsin; Egtazic Acid; Etorphine; Ganglia, Spinal; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Sodium; Sodium Fluoride; Spinal Cord | 1989 |
Monovalent ion enhancement of beta-adrenergic-stimulated adenylate cyclase activity in mouse parotid gland.
Topics: Adenylyl Cyclases; Animals; Brain; Chlorides; Colforsin; Drug Synergism; Enzyme Activation; Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Lithium; Lithium Chloride; Liver; Mice; Parotid Gland; Sodium; Thionucleotides | 1989 |
An investigation into the mechanisms of inhibition of calcium channel currents in cultured sensory neurones of the rat by guanine nucleotide analogues and (-)-baclofen.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Baclofen; Calcium Channels; Cells, Cultured; Cholera Toxin; Colforsin; Culture Techniques; Electrophysiology; Enzyme Activation; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Neurons, Afferent; Protein Kinase C; Rats; Thionucleotides; Type C Phospholipases | 1989 |
Stimulatory and inhibitory effects of forskolin on adenylate cyclase in rat normal hepatocytes and hepatoma cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Female; Guanosine Triphosphate; Liver; Liver Neoplasms, Experimental; Manganese; Pertussis Toxin; Proteins; Rats; Virulence Factors, Bordetella | 1989 |
The possible role of histamine-mediated cAMP formation as a link between H2-receptor stimulation and ultrastructural changes in guinea-pig oxyntic cells.
Topics: Animals; Colforsin; Cyclic AMP; Guanosine Triphosphate; Guinea Pigs; Histamine; In Vitro Techniques; Microtubules; Parietal Cells, Gastric; Ranitidine; Receptors, Histamine H2; Tubulin | 1989 |
Forskolin inhibits the Gs-stimulated adenylate cyclase in rat ascites hepatoma AH66F cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Ascites; Cell Membrane; Colforsin; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Liver; Liver Neoplasms, Experimental; Manganese; Rats; Theophylline; Tumor Cells, Cultured | 1989 |
Chronic norepinephrine elicits desensitization by uncoupling the beta-receptor.
Topics: Adenylyl Cyclases; Animals; Colforsin; Dogs; Drug Tolerance; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart Ventricles; Hemodynamics; Isoproterenol; Norepinephrine; Organ Size; Pindolol; Receptors, Adrenergic, beta; Sodium Fluoride; Sodium-Potassium-Exchanging ATPase; Ventricular Function | 1989 |
Protein kinase C stimulates adenylate cyclase activity in prolactin-secreting rat adenoma (GH4C1) pituicytes by inactivating the inhibitory GTP-binding protein Gi.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alkylation; Animals; Calcium; Colforsin; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Pertussis Toxin; Pituitary Neoplasms; Polymyxin B; Prolactin; Protein Kinase C; Rats; Somatostatin; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1989 |
Protective effects of cyclohexyladenosine following cerebral ischemia in the gerbil hippocampus.
Topics: Adenosine; Animals; Brain Ischemia; Colforsin; Gerbillinae; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; Random Allocation; Receptors, Purinergic; Time Factors | 1989 |
Brain forskolin binding in mice dependent on and tolerant to ethanol.
Topics: Adenylyl Cyclases; Animals; Brain; Colforsin; Drug Tolerance; Ethanol; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Male; Mice; Mice, Inbred C57BL | 1989 |
Bovine olfactory cilia preparation: thiol-modulated odorant-sensitive adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Cattle; Cell Membrane; Cell Separation; Cilia; Colforsin; Dithiothreitol; Enzyme Activation; Epithelium; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Odorants; Olfactory Mucosa; Rats; Second Messenger Systems; Smell; Thionucleotides; Turbinates | 1989 |
Dual regulation of neutrophil adenylate cyclase by fluoride and its relationship to cellular activation.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Colforsin; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Sodium Fluoride; Superoxides; Thionucleotides; Virulence Factors, Bordetella | 1987 |
GTP-dependent inhibition of insulin secretion by epinephrine in permeabilized RINm5F cells. Lack of correlation between insulin secretion and cyclic AMP levels.
Topics: Adenylate Cyclase Toxin; Calcium; Cell Line; Cell Membrane Permeability; Clonidine; Colforsin; Cyclic AMP; Epinephrine; Ethers; Guanosine Triphosphate; Insulin; Insulin Secretion; Ionomycin; Kinetics; Models, Biological; Pertussis Toxin; Propranolol; Virulence Factors, Bordetella | 1988 |
Adenylate cyclase and G-proteins as a signal transfer system in the guinea pig inner ear.
Topics: Adenylyl Cyclases; Animals; Auditory Pathways; Cholera Toxin; Cochlea; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; Organ of Corti; Receptors, Adrenergic, beta; Receptors, Cyclic AMP; Stria Vascularis | 1988 |
Prostaglandin-sensitive adenylyl cyclase of cultured preadipocytes and mature adipocytes of the rat: probable role of Gi in determination of stimulatory or inhibitory action.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Cholera Toxin; Colforsin; Cyclic AMP; Fibroblasts; GTP-Binding Proteins; Guanosine Triphosphate; Lung; Male; Membranes; Pertussis Toxin; Prostaglandins; Rats; Rats, Inbred F344; Sodium; Virulence Factors, Bordetella | 1988 |
Acute and chronic opiate-regulation of adenylate cyclase in brain: specific effects in locus coeruleus.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Colforsin; Cyclic AMP; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Locus Coeruleus; Male; Morphine; Narcotics; Neurons; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Time Factors; Virulence Factors, Bordetella | 1988 |
Characterization of corticotropin-releasing factor receptor-mediated adenylate cyclase activity in the rat central nervous system.
Topics: Adenylyl Cyclases; Animals; Brain; Brain Chemistry; Cerebral Cortex; Colforsin; Guanosine Triphosphate; Male; Rats; Rats, Inbred Strains; Receptors, Corticotropin-Releasing Hormone; Receptors, Neurotransmitter; Temperature | 1987 |
Homologous and heterologous beta-adrenergic desensitization in hepatocytes. Additivity and effect of pertussis toxin.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Female; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hypothyroidism; Isoproterenol; Liver; Pertussis Toxin; Propranolol; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Urea; Vasopressins; Virulence Factors, Bordetella | 1988 |
The new positive inotrope sulmazole inhibits the function of guanine nucleotide regulatory proteins by affecting GTP turnover.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Cardiotonic Agents; Cholera Toxin; Colforsin; Cyclic AMP; Fluorides; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1988 |
The intracellular regulation of prolactin cell function in the rainbow trout, Salmo gairdneri.
Topics: Animals; Apomorphine; Bucladesine; Calcimycin; Calcium; Colforsin; Dopamine; Female; Flunarizine; Guanosine Triphosphate; In Vitro Techniques; Pimozide; Pituitary Gland; Prolactin; Salmonidae; Trout | 1988 |
Neuropeptide Y and peptide YY inhibit adenylate cyclase activity in the rat striatum.
Topics: Adenylyl Cyclases; Animals; Colforsin; Corpus Striatum; Guanosine Triphosphate; Male; Neuropeptide Y; Peptide YY; Peptides; Rats; Rats, Inbred Strains; Receptors, Neuropeptide Y; Receptors, Neurotransmitter; Synaptic Membranes | 1988 |
Developmental changes of beta-adrenergic receptor-linked adenylate cyclase of rat liver.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Binding Sites; Colforsin; Diterpenes; Female; Fluorides; Growth Inhibitors; Guanosine Triphosphate; Iodine Radioisotopes; Liver; Male; Pindolol; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Stimulation, Chemical | 1985 |
Mechanisms of somatostatin action in pituitary cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cell Line; Colforsin; Cyclic AMP; Diterpenes; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Pituitary Gland; Prolactin; Rats; Receptors, Cell Surface; Receptors, Somatostatin; Secretory Rate; Somatostatin; Vasoactive Intestinal Peptide | 1985 |
Alpha 2-adrenergic receptors in the human cell line, HT29. Characterization with the full agonist radioligand [3H]UK-14,304 and inhibition of adenylate cyclase.
Topics: Adenocarcinoma; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Brimonidine Tartrate; Cell Line; Clonidine; Colforsin; Colonic Neoplasms; Dose-Response Relationship, Drug; Guanosine Triphosphate; Humans; Kinetics; Magnesium; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1985 |
Hormonal regulation of adenylate cyclase in the stria vascularis of the mouse.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cochlea; Colforsin; Cyclic AMP; Epinephrine; Guanosine Triphosphate; Isoproterenol; Mice; Mice, Inbred CBA; Norepinephrine; Propranolol; Receptors, Adrenergic; Stria Vascularis; Vasopressins | 1985 |
Enhancement of adenylate cyclase activity in S49 lymphoma cells by phorbol esters. Withdrawal of GTP-dependent inhibition.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Line; Chlorides; Colforsin; Cyclic AMP; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Lymphoma; Magnesium; Magnesium Chloride; Manganese; Manganese Compounds; Mathematics; Pertussis Toxin; Phorbol Esters; Somatostatin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1986 |
Evidence that PGE2 stimulates intestinal epithelial cell adenylate cyclase by a receptor-mediated mechanism.
Topics: Adenylyl Cyclases; Animals; Colforsin; Dinoprostone; Enzyme Activation; Fluorides; Guanosine Triphosphate; In Vitro Techniques; Intestinal Mucosa; Polidocanol; Polyethylene Glycols; Prostaglandins E; Rats; Receptors, Prostaglandin; Receptors, Prostaglandin E; Stimulation, Chemical | 1987 |
Modulation of guinea-pig lung adenylate cyclase by ovalbumin sensitization.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Bradykinin; Colforsin; Dose-Response Relationship, Drug; Guanosine Triphosphate; Guinea Pigs; Histamine; Immunoglobulin G; Lung; Male; Ovalbumin; Sodium Fluoride | 1988 |
Calmodulin plays a dominant role in determining neurotransmitter regulation of neuronal adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Brain; Calcium; Calmodulin; Cell Membrane; Colforsin; Guanosine Triphosphate; In Vitro Techniques; Manganese; Neurons; Neurotransmitter Agents; Rats | 1988 |
Inhibition by forskolin of excitatory amino acid-induced accumulation of cyclic AMP in guinea pig hippocampal slices.
Topics: Adenosine; Amino Acids; Animals; Aspartic Acid; Chlorides; Colforsin; Cyclic AMP; Cysteine; Drug Interactions; Ethylmaleimide; Glutamates; Glutamic Acid; Guanosine Triphosphate; Guinea Pigs; Hippocampus; Histamine; Male; N-Methylaspartate; Neurotransmitter Agents; Veratridine | 1988 |
Carboxyl terminal domain of Gs alpha specifies coupling of receptors to stimulation of adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Mice; Receptors, Adrenergic, beta; Recombinant Proteins; Somatostatin; Structure-Activity Relationship | 1988 |
Functional recovery of D1 dopamine receptor-mediated stimulation of rat striatal adenylate cyclase activity following irreversible receptor modification by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ): evidence for spare receptors.
Topics: Adenylyl Cyclases; Animals; Colforsin; Corpus Striatum; Guanosine Triphosphate; Male; Neurons; Quinolines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1 | 1986 |
Characterization of D-2 dopamine receptors in a tumor of the rat anterior pituitary gland.
Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Colforsin; Dopamine; Female; Guanosine Triphosphate; Pituitary Gland, Anterior; Pituitary Neoplasms; Rats; Rats, Inbred BUF; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone | 1987 |
Heparin and heparinoids impair adrenaline and platelet-activating factor but not thrombin-induced inhibition of adenylate cyclase and stimulation of GTP hydrolysis in human platelet membranes.
Topics: Adenosine Triphosphatases; Adenylyl Cyclase Inhibitors; Blood Platelets; Cell Membrane; Colforsin; Epinephrine; Guanosine Triphosphate; Heparin; Humans; In Vitro Techniques; Phosphorus Radioisotopes; Platelet Activating Factor; Thrombin | 1988 |
Antagonism of 5-hydroxytryptamine1A (5-HT1A) receptor-mediated modulation of adenylate cyclase activity by pindolol and propranolol isomers.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Colforsin; GTP-Binding Proteins; Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Pindolol; Propranolol; Rats; Receptors, Serotonin; Serotonin Antagonists; Stereoisomerism; Tetrahydronaphthalenes | 1988 |
Fat cell adenylate cyclase system. Enhanced inhibition by adenosine and GTP in the hypothyroid rat.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Cell Membrane; Colforsin; Cyclic AMP; Diterpenes; Female; GTP-Binding Proteins; Guanosine Triphosphate; Hypothyroidism; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic | 1985 |
Altered binding properties of beta-adrenergic receptors and lack of coupling to adenylate cyclase in P815 mastocytoma cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; Dihydroalprenolol; Diterpenes; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Mast-Cell Sarcoma; Mice; Mice, Inbred DBA; Neoplasm Proteins; Receptors, Adrenergic, beta; Sarcoma, Experimental; Sodium Fluoride | 1985 |
Properties required of a functional Ni, the GTP regulatory complex that mediates the inhibitory actions of neurotransmitters on adenylate cyclase.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cerebral Cortex; Colforsin; Diterpenes; Enzyme Activation; Ethylmaleimide; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Macromolecular Substances; Magnesium; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Purinergic | 1985 |
Adenylate cyclase activity and cyclic AMP production in the outer and inner zones of the adrenal cortex.
Topics: Adenylyl Cyclases; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Cell Membrane; Colforsin; Cyclic AMP; Diterpenes; Dose-Response Relationship, Drug; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Male; Sodium Fluoride; Time Factors; Tissue Distribution | 1985 |
Inhibition by vanadyl of adenylate cyclase activation reactions in rat adrenal membranes.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenal Glands; Animals; Bucladesine; Cell Membrane; Colforsin; Cosyntropin; Diterpenes; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Male; Rats; Rats, Inbred Strains; Thionucleotides; Vanadates; Vanadium | 1985 |
Adenylate cyclase in the corpus luteum of the rhesus monkey. III. Changes in basal and gonadotropin-sensitive activities during the luteal phase of the menstrual cycle.
Topics: Adenylyl Cyclases; Animals; Chorionic Gonadotropin; Colforsin; Corpus Luteum; Cyclic AMP; Diterpenes; Female; Gonadotropins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Luteal Phase; Luteinizing Hormone; Macaca mulatta; Progesterone | 1985 |
Comparison of cholinergic inhibition and beta-adrenergic stimulation of adenylate cyclase from rat and guinea-pig hearts: effects of guanine nucleotides and monovalent cations.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carbachol; Cations, Monovalent; Chlorides; Colforsin; Cytosol; Enzyme Activation; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Lithium; Lithium Chloride; Male; Myocardium; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride; Sodium Fluoride; Tissue Distribution | 1985 |
Possible involvement of inhibitory GTP binding regulatory protein in alpha 2-adrenoceptor-mediated inhibition of adenylate cyclase activity in cerebral cortical membranes of rats.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cell Membrane; Cerebral Cortex; Cholera Toxin; Colforsin; Epinephrine; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Male; NAD; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella | 1985 |
Uncoupling between beta-adrenoceptors and adenylate cyclase in dog ischemic myocardium.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Colforsin; Coronary Disease; Dogs; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Male; Membranes; Myocardium; Receptors, Adrenergic, beta; Sodium Fluoride; Vasoactive Intestinal Peptide | 1985 |
Large-scale purification of alpha 2-adrenergic receptor-enriched membranes from human platelets. Persistent association of guanine nucleotides with nonpurified membranes.
Topics: Adenylyl Cyclases; Blood Platelets; Cell Fractionation; Cell Membrane; Centrifugation, Density Gradient; Clonidine; Colforsin; Epinephrine; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Norepinephrine; Receptors, Adrenergic, beta; Tritium; Yohimbine | 1986 |
Expression of beta-adrenergic receptors in synchronous and asynchronous S49 lymphoma cells. II. Relationship between receptor number and response.
Topics: Adenylyl Cyclases; Alprenolol; Cell Cycle; Cell Line; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Lymphoma; Receptors, Adrenergic, beta | 1986 |
Alterations in components of adenylate cyclase associated with transformation of chicken embryo fibroblasts by Rous sarcoma virus.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Cholera Toxin; Colforsin; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Pertussis Toxin; Thionucleotides; Virulence Factors, Bordetella | 1986 |
Forskolin potentiates the stimulation of rat striatal adenylate cyclase mediated by D-1 dopamine receptors, guanine nucleotides, and sodium fluoride.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Benzazepines; Colforsin; Corpus Striatum; Cyclic AMP; Dopamine; Drug Synergism; Enzyme Activation; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Sodium Fluoride | 1986 |
Inhibition of Ns-stimulated human platelet adenylate cyclase by forskolin.
Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Alprostadil; Blood Platelets; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Ethylmaleimide; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Magnesium; Manganese; Thionucleotides | 1986 |
Relationships between the GTP content and the TSH-stimulated adenylate cyclase activity of cultured thyroid cells.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Bucladesine; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Guanosine Triphosphate; Prostaglandins E; Swine; Thyroid Gland; Thyrotropin; Time Factors | 1986 |
Pertussis toxin effects on adenylate cyclase activity, cyclic AMP accumulation and lipolysis in adipocytes from hypothyroid, euthyroid and hyperthyroid rats.
Topics: Adenosine Deaminase; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Colforsin; Cyclic AMP; Female; Glycerol; Guanosine Triphosphate; Hyperthyroidism; Hypothyroidism; Lipolysis; Norepinephrine; Pertussis Toxin; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Time Factors; Virulence Factors, Bordetella | 1986 |
Increased sensitivity of fat cell adenylate cyclase to stimulatory agonists during fasting is not related to impaired inhibitory coupling system.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Colforsin; Cyclic AMP; Fasting; GTP-Binding Proteins; Guanosine Triphosphate; Male; Niacin; Pertussis Toxin; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Time Factors; Virulence Factors, Bordetella | 1986 |
Atrial natriuretic factor receptors are negatively coupled to adenylate cyclase in cultured atrial and ventricular cardiocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Animals, Newborn; Cells, Cultured; Colforsin; Dopamine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart Atria; Heart Ventricles; Isoproterenol; Myocardium; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Thionucleotides | 1986 |
Effects of delta 9-tetrahydrocannabinol on glucagon receptor coupling to adenylate cyclase in rat liver plasma membranes.
Topics: Adenylyl Cyclases; Animals; Cannabinoids; Cell Membrane; Colforsin; Dronabinol; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glucagon; Sodium Fluoride | 1986 |
Alpha 2-adrenoceptor-GTP binding regulatory protein-adenylate cyclase system in cerebral cortical membranes of adult and senescent rats.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Aging; Animals; Cerebral Cortex; Clonidine; Colforsin; Epinephrine; Female; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Male; Membranes; NAD; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella | 1986 |
Inhibitory action of forskolin on adenylate cyclase activity and cyclic AMP generation.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Drug Synergism; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Leydig Cells; Luteinizing Hormone; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Testosterone; Virulence Factors, Bordetella | 1986 |
Fasting increases fat cell adenylate cyclase sensitivity to stimulatory agonists through enhanced ability of the stimulatory regulatory component Ns to dissociate.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cholera Toxin; Colforsin; Fasting; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Macromolecular Substances; Male; Manganese; Rats; Receptors, Adrenergic, beta | 1986 |
Characteristics of the beta-adrenergic stimulation of adenylate cyclase activity in rat ventral prostate and its modulation by androgens.
Topics: Adenylyl Cyclases; Androgens; Animals; Colforsin; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Guanosine Triphosphate; Isoproterenol; Male; Norepinephrine; Propranolol; Prostate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1986 |
A dose-response study of forskolin, stimulatory hormone, and guanosine triphosphate analog on adenylate cyclase from several sources.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cell Membrane; Colforsin; Drug Synergism; Enzyme Activation; Epinephrine; Erythrocyte Membrane; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hormones; Liver; Rabbits; Rats; Solubility | 1986 |
Pertussis toxin attenuates atrial natriuretic factor-mediated inhibition of adenylate cyclase. Involvement of inhibitory guanine nucleotide regulatory protein.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Aorta; Atrial Natriuretic Factor; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Male; Molecular Weight; NAD; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Thionucleotides; Virulence Factors, Bordetella | 1987 |
Reduction in the activity of the stimulatory guanine nucleotide-binding protein in the myocardium of spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hypertension; Isoproterenol; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Adrenergic, beta; Sarcolemma; Thionucleotides | 1987 |
Evidence for decreased activity of guanine nucleotide binding protein in adenylate cyclase of cell membranes in human ACTH-unresponsive adrenocortical carcinoma.
Topics: Adenylyl Cyclases; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Carcinoma; Cell Membrane; Cholera Toxin; Colforsin; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Receptors, Corticotropin; Receptors, Pituitary Hormone | 1986 |
Multiple effects of phorbol esters on hormone-sensitive adenylate cyclase activity in S49 lymphoma cells.
Topics: Adenylyl Cyclases; Alprostadil; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Lymphoma; Phorbol Esters; Protein Kinase C; Receptors, Adrenergic, beta; Sodium Fluoride; Temperature; Tetradecanoylphorbol Acetate | 1987 |
Unimpaired coupling of phosphorylated, desensitized beta-adrenoceptor to Gs in a reconstitution system.
Topics: Adenylyl Cyclases; Animals; Colforsin; Erythrocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Phosphorylation; Receptors, Adrenergic, beta; Thionucleotides; Turkeys | 1987 |
Guanine nucleotide-independent inhibition of adenylate cyclase by a stimulatory hormone.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Alprostadil; Cell Membrane; Colforsin; Ethylmaleimide; Fluorides; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Thionucleotides; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1988 |
Functional reconstitution of the olfactory membrane: incorporation of the olfactory adenylate cyclase in liposomes.
Topics: Adenylyl Cyclases; Animals; Cilia; Colforsin; Epithelium; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Liposomes; Olfactory Mucosa; Phosphatidylcholines; Rana catesbeiana; Thionucleotides | 1988 |
Mechanisms for inhibition of the catalytic activity of adenylate cyclase by the guanine nucleotide-binding proteins serving as the substrate of islet-activating protein, pertussis toxin.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Brain Chemistry; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Liver; Pertussis Toxin; Rabbits; Rats; Thionucleotides; Virulence Factors, Bordetella | 1986 |
Decreased stimulation of adenylate cyclase by growth hormone-releasing factor in the anterior pituitary of old rats.
Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Growth Hormone-Releasing Hormone; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Male; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Sodium Fluoride; Vasoactive Intestinal Peptide | 1986 |
Stimulatory and inhibitory regulation of myocardial adenylate cyclase by 5'-guanylyl-imidodiphosphate.
Topics: Adenylyl Cyclases; Animals; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Magnesium; Manganese; Myocardium; Rats | 1987 |
Regulation by forskolin of octopamine-stimulated adenylate cyclase from brain of the dipterous Ceratitis capitata.
Topics: Adenylyl Cyclases; Animals; Brain; Colforsin; Diptera; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Octopamine | 1987 |
Mechanisms of lithium-vasopressin interaction in rabbit cortical collecting tubule.
Topics: Adenylyl Cyclases; Animals; Arginine Vasopressin; Cholera Toxin; Colforsin; Drug Interactions; Female; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Kidney Tubules; Kidney Tubules, Collecting; Lithium; Osmosis; Rabbits; Thionucleotides | 1987 |
A novel mechanism for the inhibition of adenylate cyclase via inhibitory GTP-binding proteins. Calmodulin-dependent inhibition of the cyclase catalyst by the beta gamma-subunits of GTP-binding proteins.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Calmodulin; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Macromolecular Substances; Pertussis Toxin; Swine; Thionucleotides; Virulence Factors, Bordetella | 1987 |
A novel site of action of a high affinity A1 adenosine receptor antagonist.
Topics: Adenylyl Cyclases; Adipose Tissue; Alprostadil; Animals; Colforsin; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Xanthines | 1988 |
GTP binding regulatory proteins of adenylate cyclase in Schistosoma mansoni at different stages of development.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Membranes; Pertussis Toxin; Schistosoma mansoni; Serotonin; Sodium Fluoride; Thionucleotides; Virulence Factors, Bordetella | 1988 |
Adenylate cyclase in membrane fractions of RIN-A2-cells: studies with forskolin, NaF, GppNHp and NEM.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cells, Cultured; Colforsin; Ethylmaleimide; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Rats; Sodium Fluoride | 1988 |
Binding of [3H]forskolin to human platelet membranes. Regulation by guanyl-5'-yl imidodiphosphate, NaF, and prostaglandins E1 and D2.
Topics: Alprostadil; Binding Sites; Blood Platelets; Cell Membrane; Colforsin; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Kinetics; Prostaglandin D2; Prostaglandins D; Sodium Fluoride | 1986 |
Influences of pertussis toxin, guanine nucleotides and forskolin on adenylate cyclase in striatal membranes of infant, adult and senescent rats.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Aging; Animals; Colforsin; Corpus Striatum; Dopamine; Female; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Virulence Factors, Bordetella | 1987 |
The odorant-sensitive adenylate cyclase of olfactory receptor cells. Differential stimulation by distinct classes of odorants.
Topics: Adenylyl Cyclases; Animals; Cilia; Colforsin; Enzyme Activation; Fruit; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Magnoliopsida; Male; Odorants; Olfactory Mucosa; Plants; Rana catesbeiana; Rats; Sensory Receptor Cells; Solvents; Thionucleotides | 1986 |
Muscarinic receptor regulation of cardiac adenylate cyclase activity.
Topics: Adenylyl Cyclases; Animals; Colforsin; Dogs; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrolysis; Kinetics; Magnesium; Magnesium Chloride; Myocardium; Receptors, Muscarinic; Sarcolemma | 1987 |
Adenylate cyclase stimulation by VIP in rat and human parotid membranes.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Isoproterenol; Male; Parotid Gland; Rats; Rats, Inbred Strains; Species Specificity; Vasoactive Intestinal Peptide | 1987 |
Neuropeptide Y inhibits forskolin-stimulated adenylate cyclase activity in rat hippocampus.
Topics: Adenylyl Cyclases; Animals; Colforsin; Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Male; Neuropeptide Y; Pancreatic Polypeptide; Peptide YY; Peptides; Rats; Rats, Inbred Strains | 1987 |
Ca2+/calmodulin distinguishes between guanyl-5'-yl-imidodiphosphate- and opiate-mediated inhibition of rat striatal adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Animals; Calcium; Calmodulin; Colforsin; Corpus Striatum; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Magnesium; Male; Morphine; Rats; Rats, Inbred Strains; Temperature | 1987 |
Effect of chronic administration of doxorubicin on cardiac adenylate cyclase activity in mice.
Topics: Adenylyl Cyclases; Animals; Colforsin; Doxorubicin; Guanosine Triphosphate; Heart; Isoproterenol; Male; Mice; Myocardium; Organ Size; Sodium Fluoride | 1986 |
Maintenance of whole cell isoproterenol and forskolin responsiveness in adenylate cyclase of permeabilized cells.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Astrocytoma; Cell Line; Cell Membrane Permeability; Colforsin; Digitonin; Guanosine Triphosphate; Isoproterenol; Kinetics; Rats | 1986 |
Phorbol esters increase GTP-dependent adenylate cyclase activity in rat brain striatal membranes.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Corpus Striatum; Dopamine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Male; Phorbol Esters; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
Forskolin activation of adenylate cyclase in mouse parotid membranes.
Topics: Adenylyl Cyclases; Animals; Colforsin; Enzyme Activation; Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Mice; Parotid Gland; Thionucleotides | 1986 |
Age dependence of adenylate cyclase in guinea pig ureter homogenate.
Topics: Adenylyl Cyclases; Aging; Alprostadil; Animals; Colforsin; Enzyme Activation; Ethanol; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Male; Muscle Contraction; Propranolol; Sodium Fluoride; Ureter | 1986 |
Effect of cholera toxin on the activation of adenylate cyclase by calmodulin in bovine striatum.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Calmodulin; Cattle; Cholera Toxin; Colforsin; Corpus Striatum; Dopamine; Enzyme Activation; Guanosine Triphosphate; Manganese | 1986 |
The hysteretic effect of Gpp(NH)p on adenylate cyclase is not altered by Mg2+ in adipocyte membranes of ob/ob mice.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cholera Toxin; Colforsin; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Magnesium; Male; Mice; Mice, Obese; Pertussis Vaccine; Regression Analysis; Sodium Fluoride | 1986 |
Regional modulation of [3H]forskolin binding in the rat brain by guanylyl-5'-imidodiphosphate and sodium fluoride: comparison with the distribution of guanine nucleotide binding sites.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Brain; Colforsin; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Male; Rats; Rats, Inbred Strains; Sodium Fluoride; Tissue Distribution | 1986 |
Stimulation and inhibition of rat basophilic leukemia cell adenylate cyclase by forskolin.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Basophils; Cell Line; Cell Membrane; Colforsin; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Leukemia, Experimental; Magnesium; Rats; Thionucleotides | 1985 |
Chymotrypsin selectively decreases forskolin stimulation of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Chymotrypsin; Colforsin; Erythrocyte Membrane; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Thionucleotides; Turkeys | 1985 |
The mitogenic/oncogenic p21 Ki-RAS protein stimulates adenylate cyclase activity early in the G1 phase of NRK rat kidney cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Colforsin; Enzyme Activation; Fibroblasts; Guanosine Triphosphate; Interphase; Kidney; Kirsten murine sarcoma virus; Neoplasm Proteins; Proto-Oncogene Proteins p21(ras); Rats; Temperature; Viral Proteins | 1985 |
Treatment of oocyte membranes with the 2',3'-dialdehyde of guanosine triphosphate reduces progesterone inhibition of adenylyl cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cell Membrane; Colforsin; Diterpenes; Enzyme Activation; Female; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Manganese; Membrane Proteins; Oocytes; Progesterone; Xenopus laevis | 1985 |
Ninhibin: a sperm factor attenuates the atrial natriuretic factor mediated inhibition of adenylate cyclase: possible involvement of inhibitory guanine nucleotide regulatory protein.
Topics: Acrosin; Adenylyl Cyclase Inhibitors; Animals; Aorta; Cattle; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Endopeptidases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Male; Natriuretic Agents; Proteins; Rats; Thionucleotides | 1985 |
Multiple defects in the activity of adenylate cyclase from the Drosophila memory mutant rutabaga.
Topics: Abdomen; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Calcium; Colforsin; Diterpenes; Drosophila melanogaster; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Head; Memory; Mutation; Octopamine; Thionucleotides; Thorax | 1985 |
Defective responsiveness of adenylate cyclase to forskolin in the Drosophila memory mutant rutabaga.
Topics: Adenylyl Cyclases; Animals; Chromosome Mapping; Colforsin; Drosophila melanogaster; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Magnesium; Membranes; Memory; Octopamine; Sodium Fluoride; Thionucleotides; Trifluoperazine | 1985 |
Synthesis of 2',3'-O-(2,4,6-trinitrocyclohexadienylidine)guanosine 5'-triphosphate and a study of its inhibitory properties with adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Alkaline Phosphatase; Animals; Azides; Binding, Competitive; Chemical Phenomena; Chemistry; Chick Embryo; Colforsin; Enzyme Activation; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; Myocardium; Photochemistry; Sodium Fluoride; Spectrophotometry | 1986 |
Characterization of the adenylate cyclase of the rat corpus luteum during luteolysis induced by a prostaglandin F2 alpha analogue.
Topics: Adenylyl Cyclases; Animals; Cloprostenol; Colforsin; Corpus Luteum; Drug Synergism; Enzyme Activation; Female; Guanosine Triphosphate; Isoproterenol; Luteolytic Agents; Magnesium; Prostaglandins F, Synthetic; Rats; Rats, Inbred Strains; RNA Cap Analogs | 1986 |
Forskolin stimulation of adenylate cyclase in human thyroid membranes.
Topics: Adenylyl Cyclases; Cell Membrane; Colforsin; Diterpenes; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Magnesium; Manganese; Thyroid Gland; Thyrotropin | 1985 |
Regulation of [3H]forskolin binding to human platelet membranes by GppNHp, NaF, and prostaglandin E1.
Topics: Alprostadil; Binding Sites; Blood Platelets; Cell Membrane; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Kinetics; Prostaglandins E; Sodium Fluoride | 1985 |
Streptozotocin-induced diabetes and hormone sensitivity of adenylate cyclase in rat myocardial sarcolemma, aorta and liver.
Topics: Adenylyl Cyclases; Animals; Aorta; Catecholamines; Colforsin; Corpus Striatum; Diabetes Mellitus, Experimental; Diterpenes; Glucagon; Guanosine Triphosphate; Hormones; Liver; Male; Myocardium; Rats; Rats, Inbred Strains; Sarcolemma | 1985 |
Opposite effects of ethanol on the activation of adenylyl cyclase in human corpus luteum membranes.
Topics: Adenylyl Cyclases; Adult; Cell Membrane; Chorionic Gonadotropin; Colforsin; Corpus Luteum; Diterpenes; Drug Synergism; Enzyme Activation; Ethanol; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Sodium Fluoride | 1985 |
Effect of pentobarbital dependence on adenylate cyclase activity and calmodulin levels in rat cerebral cortex.
Topics: Adenylyl Cyclases; Animals; Calcium; Calmodulin; Cerebral Cortex; Colforsin; Diterpenes; Dopamine; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Pentobarbital; Rats; Rats, Inbred Strains; Substance-Related Disorders | 1985 |
2',3'-Dialdehyde of GTP blocks regulatory functions of adenylate cyclase NS protein.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cattle; Caudate Nucleus; Colforsin; Diterpenes; Enzyme Activation; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Kinetics; Lung; Magnesium; Polyethylene Glycols | 1985 |
Ca2+-dependent inhibition of smooth muscle adenylate cyclase activity.
Topics: Adenylyl Cyclase Inhibitors; Animals; Calcium; Calmodulin; Cattle; Colforsin; Diterpenes; Enzyme Activation; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Magnesium; Muscle Contraction; Muscle, Smooth, Vascular; Troponin; Troponin C | 1985 |
Modulation of adenylate cyclase of human platelets by phorbol ester. Impairment of the hormone-sensitive inhibitory pathway.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Blood Platelets; Catalysis; Colforsin; Diterpenes; Enzyme Activation; Epinephrine; Guanosine Triphosphate; Humans; Phorbols; Prostaglandins E; Tetradecanoylphorbol Acetate; Thrombin | 1985 |
Adenylate cyclase activity and motor behavior following cerebral ischemia in the unanesthetized gerbil.
Topics: Adenylyl Cyclases; Animals; Carotid Arteries; Cerebral Cortex; Colforsin; Diterpenes; Gerbillinae; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; Ischemic Attack, Transient; Isoproterenol; Ligation; Male; Motor Activity; Time Factors | 1985 |
Protein kinase C interferes with Ni-mediated inhibition of human platelet adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Blood Platelets; Cell Membrane; Chickens; Colforsin; Enzyme Activation; Epinephrine; Female; Guanosine Triphosphate; Humans; Oviducts; Protein Kinase C; Tetradecanoylphorbol Acetate | 1985 |
Islet-activating protein prevents nicotinic acid-induced GTPase stimulation and GTP but not GTP gamma S-induced adenylate cyclase inhibition in rat adipocytes.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Bacterial Proteins; Cell Membrane; Colforsin; Diterpenes; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Male; Nicotinic Acids; Pertussis Toxin; Phosphoric Monoester Hydrolases; Rats; Sodium Chloride; Thionucleotides; Virulence Factors, Bordetella | 1983 |
The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Subunit dissociation and the inhibition of adenylate cyclase in S49 lymphoma cyc- and wild type membranes.
Topics: Adenylyl Cyclases; Animals; Antihypertensive Agents; Cell Line; Cell Membrane; Colforsin; Diterpenes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Lymphoma; Mice; Molecular Weight; Mutation; Receptors, Cell Surface; Somatostatin; Thionucleotides | 1984 |
Forskolin stimulates adenylate cyclase activity, cyclic AMP accumulation, and adrenocorticotropin secretion from mouse anterior pituitary tumor cells.
Topics: Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Calcimycin; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Guanosine Triphosphate; Kinetics; Male; Mice; Pituitary Gland, Anterior; Pituitary Neoplasms; Rats; Rats, Inbred Strains; Somatostatin | 1984 |
Regulation of adenylate cyclase in cultured cardiocytes from neonatal rats by adenosine and other agonists.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Animals, Newborn; Catecholamines; Cells, Cultured; Colforsin; Diterpenes; Enzyme Activation; Guanosine Triphosphate; Microscopy, Electron; Myocardium; Rats; Receptors, Cell Surface; Receptors, Purinergic | 1983 |
Phosphatidylcholine-promoted interaction of the catalytic and regulatory proteins of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Antihypertensive Agents; Cholesterol; Colforsin; Detergents; Dimyristoylphosphatidylcholine; Diterpenes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Liver; Macromolecular Substances; Phosphatidylcholines; Rabbits; Receptors, Cell Surface; Thermodynamics; Thionucleotides | 1982 |
Regulation of adenylate cyclase and cyclic AMP phosphodiesterase by 5-hydroxytryptamine and calcium ions in blowfly salivary-gland homogenates.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Calcium; Colforsin; Diptera; Diterpenes; Enzyme Activation; Guanosine Triphosphate; In Vitro Techniques; Salivary Glands; Serotonin | 1982 |
Guanosine 5'-(beta, gamma-imido)triphosphate inhibition of forskolin-activated adenylate cyclase is mediated by the putative inhibitory guanine nucleotide regulatory protein.
Topics: Adenylyl Cyclases; Animals; Antihypertensive Agents; Blood Proteins; Cell Membrane; Cerebral Cortex; Colforsin; Corpus Striatum; Diterpenes; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface | 1982 |
The role of a guanine nucleotide-binding protein in the activation of rat liver plasma-membrane adenylate cyclase by forskolin.
Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Azides; Cell Membrane; Colforsin; Diterpenes; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; In Vitro Techniques; Liver; Rats; Receptors, Cell Surface; Ultraviolet Rays | 1983 |
Forskolin stimulates adenylate cyclase activity, adenosine 3',5'-monophosphate production and peptide release from the intermediate lobe of the rat pituitary gland.
Topics: Adenylyl Cyclases; Animals; Antihypertensive Agents; Apomorphine; Colforsin; Cyclic AMP; Diterpenes; Guanosine Triphosphate; Isoproterenol; Kinetics; Melanocyte-Stimulating Hormones; Pituitary Gland; Rats | 1984 |
The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Properties and function of the purified protein.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Antihypertensive Agents; Bacterial Toxins; Blood Platelets; Cell Membrane; Colforsin; Diterpenes; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Magnesium; Molecular Weight; Pertussis Toxin; Prostaglandins E; Receptors, Cell Surface; Sodium Fluoride; Thionucleotides; Virulence Factors, Bordetella | 1984 |
Effects of guanine nucleotides and divalent cations on forskolin activation of rabbit luteal adenylyl cyclase: evidence for the existence of an inhibitory guanine nucleotide-binding regulatory component.
Topics: Adenylyl Cyclases; Animals; Cations, Divalent; Colforsin; Corpus Luteum; Diterpenes; Enzyme Activation; Female; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Magnesium; Magnesium Chloride; Rabbits; Receptors, Cell Surface | 1984 |
Calcium inhibition of parathyroid adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Calcium; Colforsin; Diterpenes; Egtazic Acid; Guanosine Triphosphate; Kinetics; Mathematics; Parathyroid Glands; Sodium Fluoride; Swine | 1984 |
[Pertussis toxin stimulates brain adenyl cyclase and induces ADP ribosylation of a 40,000 dalton membrane protein].
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bacterial Toxins; Brain; Colforsin; Diterpenes; Guanosine Triphosphate; Membrane Proteins; Molecular Weight; NAD; Nucleoside Diphosphate Sugars; Pertussis Toxin; Rats; Synaptic Membranes; Virulence Factors, Bordetella | 1983 |
Dopaminergic inhibition of adenylate cyclase correlates with high affinity agonist binding to anterior pituitary D2 dopamine receptors.
Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Colforsin; Diterpenes; Dopamine; Dose-Response Relationship, Drug; Female; Guanosine Triphosphate; Pituitary Gland, Anterior; Receptors, Dopamine; Sodium Fluoride; Swine; Tetrahydronaphthalenes | 1984 |
Activation of adenylate cyclase by dopamine, GTP, NaF and forskolin in striatal membranes of neonatal, adult and senescent rats.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Colforsin; Corpus Striatum; Diterpenes; Dopamine; Enzyme Activation; Female; Guanosine Triphosphate; In Vitro Techniques; Male; Membranes; Rats; Rats, Inbred Strains; Sodium Fluoride | 1984 |
Forskolin regulation of liver membrane adenylyl cyclase.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Membrane; Chemical Phenomena; Chemistry; Colforsin; Diterpenes; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Liver; Rats; Sodium Fluoride | 1983 |
The dual effects of aluminum as activator and inhibitor of adenylate cyclase in the liver fluke Fasciola hepatica.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Colforsin; Diterpenes; Enzyme Activation; Fasciola hepatica; Guanosine Triphosphate; Serotonin; Sodium Fluoride | 1983 |
Effect of thyrotropin-induced desensitization of bovine thyroid adenylate cyclase on the nucleotide regulatory protein.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adenylyl Imidodiphosphate; Alprostadil; Animals; Cattle; Cholera Toxin; Colforsin; Diterpenes; Drug Tolerance; Guanosine Triphosphate; Prostaglandins E; Thyroid Gland; Thyrotropin | 1983 |
Forskolin-activated adenylate cyclase. Inhibition by guanyl-5'-yl imidodiphosphate.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Animals; Colforsin; Diterpenes; Enzyme Activation; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Magnesium; Male; Manganese; Rats; Rats, Inbred Strains | 1983 |
Enkephalin-mediated inhibition of forskolin-stimulated rabbit luteal adenylyl cyclase activity.
Topics: Adenylyl Cyclases; Animals; Colforsin; Corpus Luteum; Diterpenes; Enkephalin, Methionine; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Rabbits | 1983 |
Pertussis toxin reverses Gpp(NH)p inhibition of basal and forskolin activated adipocyte adenylate cyclase.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Bacterial Toxins; Colforsin; Diterpenes; Enzyme Activation; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Pertussis Toxin; Rabbits; Rats; Rats, Inbred Strains; Time Factors; Virulence Factors, Bordetella | 1983 |
Catalytic unit of adenylate cyclase: reduced activity in aged-human lymphocytes.
Topics: Adenylyl Cyclases; Adult; Aged; Aging; Colforsin; Diterpenes; Enzyme Activation; Guanosine Triphosphate; Humans; Isoproterenol; Lymphocytes; Male; Sodium Fluoride | 1982 |
Regulation of adenylate cyclase of human platelet membranes by forskolin.
Topics: Adenylyl Cyclases; Adult; Alprostadil; Antihypertensive Agents; Blood Platelets; Cell Membrane; Cholera Toxin; Colforsin; Diterpenes; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Kinetics; Male; Prostaglandins E; Sodium Fluoride; Thionucleotides | 1982 |
Olfactory transduction mechanisms in sheep.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Epithelium; Ethylamines; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Inositol Phosphates; Kinetics; Odorants; Olfactory Mucosa; Sheep; Signal Transduction; Smell | 1995 |
GTP requirement for isoproterenol activation of calcium channels in vascular myocytes.
Topics: Animals; Calcium Channels; Colforsin; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Male; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Rabbits; Thionucleotides | 1995 |
Activation of K+ channels by ritodrine hydrochloride in uterine smooth muscle cells from pregnant women.
Topics: Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Female; Guanosine Triphosphate; Humans; Muscle, Smooth; Patch-Clamp Techniques; Phosphorylation; Potassium Channels; Pregnancy; Ritodrine; Uterine Contraction; Uterus | 1994 |
Partial agonism of theophylline-7-riboside on adenosine receptors.
Topics: Animals; Cells, Cultured; Colforsin; Guanosine Triphosphate; Purinergic P1 Receptor Agonists; Rats; Receptors, Purinergic P1; Temperature; Theophylline; Xanthine; Xanthines | 1994 |
Evidence for regulated coupling of A1 adenosine receptors by phosphorylation in Zucker rats.
Topics: Adenosine; Adenylyl Cyclases; Adipocytes; Animals; Cell Membrane; Colforsin; Cyclic AMP; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Iodine Radioisotopes; Iodobenzenes; Obesity; Phosphorylation; Proteins; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Rats, Zucker; Receptors, Purinergic P1 | 1995 |
Bovine hereditary cardiomyopathy: an animal model of human dilated cardiomyopathy.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cardiomyopathies; Cardiomyopathy, Dilated; Catecholamines; Cattle; Cattle Diseases; Colforsin; Disease Models, Animal; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; Heart Atria; Heart Ventricles; Humans; Isoproterenol; Manganese; Myocardial Contraction; Myocardium; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Reference Values; Sodium Fluoride; Ventricular Function, Right; Virulence Factors, Bordetella | 1995 |
Vasotocin-sensitive adenylate cyclase in frog glomeruli.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Arginine Vasopressin; Colforsin; Female; Guanosine Triphosphate; Kidney Glomerulus; Kidney Tubules, Collecting; Kinetics; Magnesium Chloride; Male; Pituitary Hormones, Posterior; Rana ridibunda; Vasotocin | 1995 |
G-proteins and adenylyl cyclase in ovarian granulosa cells of amago salmon (Oncorhynchus rhodurus).
Topics: Adenosine; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Female; Gonadotropins; Granulosa Cells; GTP-Binding Proteins; Guanosine Triphosphate; Molecular Weight; Oncorhynchus; Pertussis Toxin; Virulence Factors, Bordetella | 1994 |
Somatostatin receptor-effector system in rat pancreatic acinar membranes after subtotal enterectomy.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hyperplasia; Intestine, Small; Male; Pancreas; Postoperative Period; Rats; Receptors, Somatostatin; Somatostatin; Time Factors | 1995 |
Beta-adrenergic agonists regulate KCa channels in airway smooth muscle by cAMP-dependent and -independent mechanisms.
Topics: Adenylyl Imidodiphosphate; Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Horses; Ion Channel Gating; Isoproterenol; Kinetics; Membrane Potentials; Muscle, Smooth; Potassium Channels; Trachea | 1994 |
All five cloned human somatostatin receptors (hSSTR1-5) are functionally coupled to adenylyl cyclase.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Pertussis Toxin; Radioligand Assay; Receptors, Somatostatin; Recombinant Proteins; Signal Transduction; Somatostatin; Somatostatin-28; Transfection; Virulence Factors, Bordetella | 1994 |
Adenylyl cyclase activity in Alzheimer's disease brain: stimulatory and inhibitory signal transduction pathways are differently affected.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cerebellum; Colforsin; Enzyme Activation; Female; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; Humans; Male; Manganese; Middle Aged; Neurotransmitter Agents; Purinergic P1 Receptor Antagonists; Signal Transduction | 1994 |
A potential 5-HT1A receptor antagonist: p-MPPI.
Topics: Adenylyl Cyclases; Aminopyridines; Animals; Binding, Competitive; Colforsin; Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Ligands; Piperazines; Rats; Receptors, Serotonin; Serotonin Antagonists; Stimulation, Chemical | 1994 |
Analysis of the adenylate cyclase signalling system, and alterations induced by culture with insulin, in a novel SV40-DNA-immortalized hepatocyte cell line (P9 cells).
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Cell Transformation, Viral; Colforsin; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Insulin; Liver; Male; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Signal Transduction | 1994 |
Deletion analysis of the m4 muscarinic acetylcholine receptor. Molecular determinants for activation of but not coupling to the Gi guanine-nucleotide-binding regulatory protein regulate receptor internalization.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Carbachol; CHO Cells; Colforsin; Cricetinae; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Mice; Molecular Sequence Data; Mutagenesis; Oligodeoxyribonucleotides; Protein Structure, Secondary; Receptors, Muscarinic; Recombinant Proteins; Restriction Mapping; Sequence Deletion; Transfection | 1994 |
Identification of a ras-related protein in murine erythroleukemia cells that is a cAMP-dependent protein kinase substrate and is phosphorylated during chemically induced differentiation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Autoradiography; Blotting, Western; Cell Differentiation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cysteine; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine Triphosphate; Leukemia, Erythroblastic, Acute; Methionine; Mice; Peptide Mapping; Phosphopeptides; Phosphorylation; Proto-Oncogene Proteins; rap GTP-Binding Proteins; Recombinant Proteins; Substrate Specificity; Sulfur Radioisotopes; Transfection; Tumor Cells, Cultured | 1994 |
Analysis of vasoactive intestinal peptide receptors and the G protein regulation of adenylyl cyclase in seminal vesicle membranes from streptozotocin-diabetic rats.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Colforsin; Diabetes Mellitus, Experimental; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Male; Rats; Rats, Wistar; Receptors, Vasoactive Intestinal Peptide; Seminal Vesicles; Signal Transduction; Streptozocin; Vasoactive Intestinal Peptide | 1994 |
Characterization of cloned somatostatin receptors SSTR4 and SSTR5.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Guanosine Triphosphate; Humans; Molecular Sequence Data; Radioligand Assay; Receptors, Somatostatin; Sodium; Somatostatin | 1993 |
Acetylcholine muscarinic m1 receptor regulation of cyclic AMP synthesis controls growth factor stimulation of Raf activity.
Topics: Adenylyl Cyclases; Animals; Atropine; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Gene Expression; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Models, Biological; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Receptor Protein-Tyrosine Kinases; Receptors, Muscarinic; Receptors, Platelet-Derived Growth Factor; Transfection | 1994 |
5-Hydroxytryptamine1A receptor synthetic peptides. Mechanisms of adenylyl cyclase inhibition.
Topics: 3T3 Cells; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Clone Cells; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hippocampus; Humans; Kinetics; Male; Mice; Molecular Sequence Data; Moths; Peptide Fragments; Pertussis Toxin; Protein Structure, Secondary; Rats; Rats, Wistar; Receptors, Serotonin; Virulence Factors, Bordetella | 1994 |
Glucocorticoids regulate the development of intracellular signaling: enhanced forebrain adenylate cyclase catalytic subunit activity after fetal dexamethasone exposure.
Topics: Adenylyl Cyclases; Aging; Analysis of Variance; Animals; Body Weight; Colforsin; Dexamethasone; Female; Fluorides; Gestational Age; GTP-Binding Proteins; Guanosine Triphosphate; Macromolecular Substances; Maternal-Fetal Exchange; Membrane Proteins; Pregnancy; Prosencephalon; Rats; Rats, Sprague-Dawley; Weight Gain | 1993 |
Platelets from spontaneously hypertensive rats exhibit decreased expression of inhibitory guanine nucleotide regulatory protein. Relation with adenylyl cyclase activity.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Alprostadil; Animals; Blood Platelets; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1993 |
A single residue, aspartic acid 95, in the delta opioid receptor specifies selective high affinity agonist binding.
Topics: Animals; Aspartic Acid; Base Sequence; Binding Sites; Binding, Competitive; Cell Line; Chlorocebus aethiops; Colforsin; Cyclic AMP; Enkephalins; Guanosine Triphosphate; In Vitro Techniques; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Narcotics; Oligodeoxyribonucleotides; Protein Binding; Receptors, Opioid, delta; Recombinant Proteins; Signal Transduction; Sodium; Structure-Activity Relationship | 1993 |
Effects of hydrogen peroxide on stimulatory guanine nucleotide-binding protein in rat heart.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Colforsin; Cyclic AMP; Dihydroalprenolol; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; Hydrogen Peroxide; In Vitro Techniques; Isoproterenol; Lymphoma; Male; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1993 |
Characterization of adenylyl cyclase in goldfish brain.
Topics: Adenylyl Cyclases; Animals; Brain; Calcium; Calmodulin; Colforsin; Cyclic AMP; Goldfish; Guanosine Triphosphate; Magnesium; Manganese | 1993 |
Estrogen uncouples beta-adrenergic receptor from the stimulatory guanine nucleotide-binding protein in female rat hypothalamus.
Topics: Adenylyl Cyclases; Animals; Colforsin; Enzyme Activation; Estradiol; Female; GTP-Binding Proteins; Guanosine Triphosphate; Hypothalamus; Isoproterenol; Ovariectomy; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Uncoupling Agents | 1993 |
Regulation of Ca2+ current in frog ventricular cardiomyocytes by guanosine 5'-triphosphate analogues and isoproterenol.
Topics: Acetylcholine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Calcium Channel Blockers; Calcium Channels; Colforsin; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; In Vitro Techniques; Isoproterenol; Myocardium; Rana catesbeiana | 1993 |
Separate GTP binding and GTPase activating domains of a G alpha subunit.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Cell Line; Colforsin; Cyclic AMP; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hydrolysis; Kinetics; Molecular Sequence Data; Mutation; Protein Conformation | 1993 |
Conditional activation of cAMP signal transduction by protein kinase C. The effect of phorbol esters on adenylyl cyclase in permeabilized and intact cells.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Cell Line; Cell Membrane Permeability; Colforsin; Cyclic AMP; Guanosine Triphosphate; Isoproterenol; Mice; Molecular Sequence Data; Phorbol Esters; Protein Kinase C; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction | 1994 |
Phospholipase D treatment enhances gonadotrophin receptor-coupled adenylate cyclase activity in isolated bovine luteal cells.
Topics: Adenylyl Cyclases; Animals; Cattle; Cell Membrane; Colforsin; Epidermal Growth Factor; ErbB Receptors; Female; Guanosine Triphosphate; Luteal Cells; Luteinizing Hormone; Phosphatidic Acids; Phospholipase D; Receptors, Gonadotropin | 1993 |
Inhibition of adenylyl cyclase by Gi alpha.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Calmodulin; Cell Line; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Moths; Myristic Acid; Myristic Acids; Recombinant Proteins | 1993 |
Direct coupling of opioid receptors to both stimulatory and inhibitory guanine nucleotide-binding proteins in F-11 neuroblastoma-sensory neuron hybrid cells.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Binding, Competitive; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Cricetinae; Cricetulus; Enkephalin, Leucine-2-Alanine; Ganglia, Spinal; GTP-Binding Proteins; Guanosine Triphosphate; Hybrid Cells; Kinetics; Levorphanol; Mice; Neuroblastoma; Neurons, Afferent; Pertussis Toxin; Receptors, Opioid; Sodium; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Adenylate cyclase activity in microdissected rat liver tissue: periportal to pericentral activity gradient.
Topics: Adenylyl Cyclases; Angiotensin II; Animals; Chlorides; Cholera Toxin; Colforsin; Cyclic AMP; Glucagon; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Lithium; Lithium Chloride; Liver; Male; Rats; Rats, Sprague-Dawley; Sodium Fluoride | 1993 |
Coupling of adenosine receptors to adenylate cyclase in postischemic rat brain.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding, Competitive; Brain Ischemia; Calcium; Colforsin; Cyclic AMP; Down-Regulation; Edetic Acid; Egtazic Acid; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Heart Arrest; Male; Models, Biological; Rats; Rats, Wistar; Receptors, Purinergic; Signal Transduction | 1993 |
P2 purinergic agonists and 12-O-tetradecanoylphorbol-13-acetate, as well as protein kinase A activators, stimulate thyroglobulin secretion in FRTL-5 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate; Adenosine Triphosphate; Cells, Cultured; Colforsin; Enzyme Activation; Guanosine Triphosphate; Protein Kinases; Receptors, Purinergic; Tetradecanoylphorbol Acetate; Thyroglobulin | 1993 |
Vip-induced cross-talk between G-proteins in membranes from rat anterior pituitary cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Cells, Cultured; Cholera Toxin; Colforsin; Dopamine; Dose-Response Relationship, Drug; Enzyme Activation; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Magnesium; Models, Biological; Pertussis Toxin; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1993 |
Adrenergic desensitization in left ventricle from streptozotocin diabetic swine.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aluminum; Animals; Blood Glucose; Colforsin; Cyclic AMP; Cytosol; Diabetes Mellitus, Experimental; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Heart Ventricles; Insulin; Isoproterenol; Receptors, Adrenergic, beta; Sarcolemma; Signal Transduction; Streptozocin; Swine; Swine, Miniature | 1995 |
Binding and agonist/antagonist actions of M35, galanin(1-13)-bradykinin(2-9)amide chimeric peptide, in Rin m 5F insulinoma cells.
Topics: Animals; Binding Sites; Binding, Competitive; Bradykinin; Cell Membrane; Colforsin; Cyclic AMP; Galanin; Guanosine Triphosphate; Insulinoma; Ligands; Peptide Fragments; Pertussis Toxin; Protein Binding; Rats; Receptors, Galanin; Receptors, Gastrointestinal Hormone; Recombinant Fusion Proteins; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1995 |
Adenylyl cyclase activity in turtle vomeronasal and olfactory epithelium.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Epithelium; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Nose; Odorants; Receptors, Odorant; Signal Transduction; Smell; Turtles | 1996 |
Forskolin stimulates detoxification of brefeldin A.
Topics: Animals; Brefeldin A; Bucladesine; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclopentanes; Cysteine; Glutathione; Golgi Apparatus; Guanosine Triphosphate; Inactivation, Metabolic; Kinetics; Mycotoxins | 1996 |
Characterization of adenylyl cyclase stimulated by VIP in rat and mouse peritoneal macrophage membranes.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Intercellular Signaling Peptides and Proteins; Kinetics; Macrophages, Peritoneal; Mice; NAD; Neuropeptides; Peptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; Secretin; Sodium Fluoride; Vasoactive Intestinal Peptide | 1996 |
Involvement of pertussis toxin-sensitive and -insensitive G proteins in alpha-thrombin signalling on cultured human vascular smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Alprostadil; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Muscle, Smooth, Vascular; Pertussis Toxin; Phosphatidylinositols; Poly(ADP-ribose) Polymerases; Saponins; Signal Transduction; Thrombin; Virulence Factors, Bordetella | 1996 |
Involvement of the beta gamma subunits of inhibitory GTP-binding protein in chemoattractant receptor-mediated potentiation of cyclic AMP formation in guinea pig neutrophils.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Calcium; Cattle; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Guinea Pigs; Macromolecular Substances; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Signal Transduction; Type C Phospholipases | 1996 |
Pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal polypeptide receptor subtypes are differently expressed in rat transplanted pituitary tumours (SMtTW) and in the normal gland.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Colforsin; DNA Primers; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Neoplasm Transplantation; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Pituitary Neoplasms; Polymerase Chain Reaction; Rats; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone; Receptors, Vasoactive Intestinal Peptide; Receptors, Vasoactive Intestinal Peptide, Type II; Reference Values; RNA, Messenger; Sodium Fluoride; Transcription, Genetic | 1996 |
Neurite outgrowth of striatal neurons in vitro: involvement of purines in the growth-promoting effect of myenteric plexus explants.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Aminohydrolases; Animals; Cells, Cultured; Colforsin; Drug Interactions; Fibroblast Growth Factors; Fibronectins; Gangliosides; Guanosine Triphosphate; Laminin; Myenteric Plexus; Neostriatum; Nerve Growth Factors; Neurites; Neurons; Neuropeptides; Neurotrophin 3; Rats; Rats, Sprague-Dawley; Serotonin; Tetrodotoxin; Theophylline | 1996 |
PK 11195 blockade of benzodiazepine-induced inhibition of forskolin-stimulated adenylate cyclase activity in the striatum.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Benzodiazepines; Benzodiazepinones; Colforsin; Corpus Striatum; Diazepam; Drug Interactions; Flumazenil; GABA-A Receptor Antagonists; Guanosine Triphosphate; Indoles; Isoquinolines; Kinetics; Male; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Virulence Factors, Bordetella | 1996 |
Beta-adrenoceptor desensitization despite cardiac denervation in human failing transplanted myocardium.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Biopsy; Colforsin; Denervation; GTP-Binding Proteins; Guanosine Triphosphate; Heart Transplantation; Heart Ventricles; Humans; Isoproterenol; Ventricular Function, Left | 1996 |
In vivo reconstitution of dopamine D2S receptor-mediated G protein activation in baculovirus-infected insect cells: preferred coupling to Gi1 versus Gi2.
Topics: Adenosine Triphosphate; Animals; Apomorphine; Baculoviridae; Binding, Competitive; Cell Line; Colforsin; Cyclic AMP; Dopamine Agonists; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Receptors, Dopamine D2; Spiperone; Spodoptera | 1996 |
Hypothyroidism alters the effect of GTP on adenylyl cyclase in forebrain and hindbrain synaptosomal membranes from 15-day-old rats.
Topics: Adenylyl Cyclases; Animals; Colforsin; Critical Period, Psychological; Female; Guanosine Triphosphate; Hypothyroidism; Pregnancy; Prosencephalon; Rats; Rats, Sprague-Dawley; Rhombencephalon; Synaptosomes | 1996 |
Neurite outgrowth in PC12 cells is enhanced by guanosine through both cAMP-dependent and -independent mechanisms.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Antineoplastic Agents; Colforsin; Cyclic AMP; Enzyme Inhibitors; Guanosine; Guanosine Triphosphate; Nerve Growth Factors; Neurites; PC12 Cells; Rats | 1996 |
Enhancement of the ATP-sensitive K+ current by extracellular ATP in rat ventricular myocytes. Involvement of adenylyl cyclase-induced subsarcolemmal ATP depletion.
Topics: Adenine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Benzopyrans; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Colforsin; Cromakalim; Deoxyadenine Nucleotides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; GTP-Binding Proteins; Guanidines; Guanosine Triphosphate; Heart Ventricles; Male; Patch-Clamp Techniques; Peptide Fragments; Pinacidil; Potassium Channels; Pyrroles; Rats; Rats, Wistar; Uncoupling Agents | 1997 |
Temporal effects of cytokines on neonatal cardiac myocyte Ca2+ transients and adenylate cyclase activity.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Animals, Newborn; Calcium; Cells, Cultured; Colforsin; Guanosine Triphosphate; Heart; Heart Ventricles; Interleukin-1; Isoproterenol; Kinetics; Myocardial Contraction; Myocardium; Rats; Time Factors; Tumor Necrosis Factor-alpha | 1997 |
Ontogeny of regulatory mechanisms for beta-adrenoceptor control of rat cardiac adenylyl cyclase: targeting of G-proteins and the cyclase catalytic subunit.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Animals, Newborn; Body Weight; Carbachol; Cell Membrane; Colforsin; Drug Hypersensitivity; Female; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine Triphosphate; Heart; Isoproterenol; Male; Manganese; Membrane Proteins; Muscarinic Agonists; Myocardium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Time Factors | 1997 |
Right ventricular infundibular beta-adrenoceptor complex in tetralogy of Fallot patients.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Child; Child, Preschool; Colforsin; Female; Guanosine Triphosphate; Heart Ventricles; Humans; Hypoxia; Imidazoles; In Vitro Techniques; Infant; Isoproterenol; Male; Myocardium; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Sodium Fluoride; Tetralogy of Fallot | 1997 |
Differential regulation of adenylyl cyclases by Galphas.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Cell Line; Colforsin; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gs; Guanosine Triphosphate; Humans; Kinetics; Liver; Reticulocytes; Spodoptera | 1997 |
Desensitization and internalization of adenosine A1 receptors in rat brain by in vivo treatment with R-PIA: involvement of coated vesicles.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Coated Vesicles; Colforsin; Enzyme Activation; Guanosine Triphosphate; Immunoblotting; Intracellular Membranes; Male; Microsomes; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Rats, Wistar; Receptors, Purinergic P1; Vasodilator Agents; Xanthines | 1996 |
Sensitization of G protein-coupled benzodiazepine receptors in the striatum of 6-hydroxydopamine-lesioned rats.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Corpus Striatum; Diazepam; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Male; Oxidopamine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Signal Transduction; Substantia Nigra; Tritium | 1997 |
Ontogenic development of the adenylyl cyclase enzyme and the alpha s, alpha i1 and alpha i2 G-protein regulatory subunits from rat prostate.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Blotting, Northern; Colforsin; Gene Expression Regulation, Enzymologic; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Male; Prostate; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Testosterone; Transcription, Genetic; Vasoactive Intestinal Peptide | 1997 |
Molecular diversity of adenylyl cyclases in human and rat myometrium. Correlation with global adenylyl cyclase activity during mid- and term pregnancy.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Dose-Response Relationship, Drug; Female; Guanosine Triphosphate; Humans; Isoproterenol; Myometrium; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Rats; Rats, Sprague-Dawley; Sympathomimetics; Transducin | 1997 |
Pieces of the true grail: a G protein finds its target.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Binding Sites; Catalysis; Cell Membrane; Colforsin; Crystallization; Crystallography, X-Ray; Cyclic AMP; Cytoplasm; Dimerization; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine Triphosphate; Models, Molecular; Protein Structure, Secondary | 1997 |
Nutrient augmentation of Ca2+-dependent and Ca2+-independent pathways in stimulus-coupling to insulin secretion can be distinguished by their guanosine triphosphate requirements: studies on rat pancreatic islets.
Topics: Adenosine Triphosphate; Animals; Calcium; Colforsin; Glucose; Guanosine Triphosphate; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mycophenolic Acid; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1998 |
Protein kinase A regulates the disposition of Ca2+ which enters the cytoplasmic space through store-activated Ca2+ channels in rat hepatocytes by diverting inflowing Ca2+ to mitochondria.
Topics: Adenosine Triphosphate; Aluminum Compounds; Animals; Bucladesine; Calcium; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Enzyme Inhibitors; Fluorides; Genistein; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Liver; Mitochondria, Liver; Rats; Thapsigargin; Vasopressins | 1998 |
Glucose augmentation of mastoparan-stimulated insulin secretion in rat and human pancreatic islets.
Topics: Adenosine Triphosphate; Animals; Calcium; Colforsin; Glucose; Guanosine Triphosphate; Humans; Insulin; Insulin Secretion; Intercellular Signaling Peptides and Proteins; Islets of Langerhans; Keto Acids; Male; Mannoheptulose; Organ Culture Techniques; Peptides; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Wasp Venoms | 1998 |
Molecular mechanisms of adenylyl cyclase desensitization in pregnant rat myometrium following in vivo administration of the beta-adrenergic agonist, isoproterenol.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colforsin; Drug Tolerance; Female; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Myometrium; Pindolol; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; RNA, Messenger | 1998 |
Glucocorticoid-targeting of the adenylyl cyclase signaling pathway in the cerebellum of young vs. aged rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Anti-Inflammatory Agents; Cerebellum; Colforsin; Dexamethasone; Fluorides; Glucocorticoids; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Kidney; Male; Manganese; Rats; Rats, Sprague-Dawley; Signal Transduction | 1998 |
Activation of cAMP synthesis in rat brain cortical membranes by rubidium and cesium ions.
Topics: Animals; Cerebral Cortex; Cesium; Chlorides; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Guanosine Triphosphate; In Vitro Techniques; Magnesium Chloride; Rats; Rubidium | 1998 |
Developmental enhancement of secretory response to isoproterenol coupled with increases in beta-adrenoceptor density and Gs protein function in rat parotid tissues.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Colforsin; Culture Techniques; Female; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Male; Organ Size; Parotid Gland; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Muscarinic | 1998 |
Chronic oxytocin pretreatment inhibits adenylyl cyclase activity in cultured rat myometrial cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cells, Cultured; Chlorides; Colforsin; Enzyme Inhibitors; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Isoproterenol; Manganese Compounds; Myometrium; Oxytocin; Pertussis Toxin; Phenylephrine; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium Fluoride; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1998 |
Overexpression of Gi-proteins precedes the development of DOCA-salt-induced hypertension: relationship with adenylyl cyclase.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta; Atrial Natriuretic Factor; Autoradiography; Blotting, Northern; Colforsin; Desoxycorticosterone; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hypertension; Immunoblotting; Isoproterenol; Peptide Fragments; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sarcolemma; Sodium Chloride; Time Factors | 1998 |
Day/night differences in the stimulation of adenylate cyclase activity by calcium/calmodulin in chick pineal cell cultures: evidence for circadian regulation of cyclic AMP.
Topics: Adenylyl Cyclases; Animals; Calcium; Calmodulin; Cells, Cultured; Chick Embryo; Circadian Rhythm; Colforsin; Cyclic AMP; Guanosine Triphosphate; Lighting; Phosphodiesterase Inhibitors; Pineal Gland; Stimulation, Chemical | 1998 |
Blood ethanol levels and adenylyl cyclase activity in lymphocytes of alcoholic patients.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adult; Alcoholism; Case-Control Studies; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Ethanol; Guanosine Triphosphate; Humans; Longitudinal Studies; Lymphocytes; Male; Middle Aged; Phosphorus Radioisotopes; Signal Transduction | 1999 |
Dopamine receptor coupling to adenylyl cyclase in rat olfactory pathway: a combined pharmacological-radioautographic approach.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Autoradiography; Benzazepines; Bromocriptine; Carbachol; Colforsin; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Male; Muscarinic Agonists; Nitriles; Odorants; Olfactory Bulb; Olfactory Mucosa; Olfactory Pathways; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides; Signal Transduction | 1999 |
Identification of the G protein-activating domain of the natriuretic peptide clearance receptor (NPR-C).
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; Guanosine Triphosphate; Guanylate Cyclase; Guinea Pigs; Isoenzymes; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Phospholipase C beta; Protein Binding; Receptors, Atrial Natriuretic Factor; Type C Phospholipases | 1999 |
Differential G-protein activation by alkaloid and peptide opioid agonists in the human neuroblastoma cell line SK-N-BE.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alkaloids; Animals; Azides; Cell Membrane; Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Isoelectric Point; Neuroblastoma; Neurons; Oligodeoxyribonucleotides, Antisense; Oligopeptides; Peptides; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1999 |
Decreased type VI adenylyl cyclase mRNA concentration and Mg(2+)-dependent adenylyl cyclase activities and unchanged type V adenylyl cyclase mRNA concentration and Mn(2+)-dependent adenylyl cyclase activities in the left ventricle of rats with myocardial
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Blotting, Northern; Colforsin; Enzyme Activation; Gene Expression; Guanosine Triphosphate; Heart Failure; Isoenzymes; Magnesium; Male; Manganese; Microsomes; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; RNA, Messenger; Stimulation, Chemical; Time Factors | 1999 |
cAMP cascade leads to Ras activation in cortical neurons.
Topics: Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Enzyme Activation; Fetus; Guanosine Triphosphate; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; PC12 Cells; Phorbol 12,13-Dibutyrate; ras GTPase-Activating Proteins; ras Proteins; Rats; Signal Transduction | 2000 |
Magnetic field desensitizes 5-HT(1B) receptor in brain: pharmacological and functional studies.
Topics: Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electromagnetic Fields; Guanosine Triphosphate; Guinea Pigs; Humans; In Vitro Techniques; Ligands; Protein Conformation; Pyridines; Pyrroles; Rats; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Synaptosomes; Temperature; Transfection | 2000 |
Signal transduction characteristics of the corticotropin-releasing hormone receptors in the feto-placental unit.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Amino Acid Sequence; Binding Sites; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Extraembryonic Membranes; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Inositol Phosphates; Molecular Sequence Data; Placenta; Pregnancy; Receptors, Corticotropin-Releasing Hormone; Signal Transduction; Virulence Factors, Bordetella | 2000 |
Adenylyl cyclase regulates signal onset via the inhibitory GTP-binding protein, Gi.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Mice; Molecular Mimicry; Receptor, Muscarinic M4; Receptors, Muscarinic; Signal Transduction; Somatostatin; Tumor Cells, Cultured | 2000 |
TSH and cAMP do not signal mitogenesis through Ras activation.
Topics: Adenylyl Cyclases; Animals; Carbachol; Cell Cycle; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Dogs; Enzyme Activation; Epidermal Growth Factor; Guanosine Triphosphate; Hepatocyte Growth Factor; Insulin; Mitogens; ras Proteins; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Time Factors | 2000 |
Differential alterations in cardiac adrenergic signaling in chronic hypoxia or norepinephrine infusion.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cholera Toxin; Chronic Disease; Colforsin; GTP-Binding Proteins; Guanosine Triphosphate; Heart Rate; Heart Ventricles; Hypertrophy, Left Ventricular; Hypertrophy, Right Ventricular; Hypoxia; Isoproterenol; Male; Myocardium; Norepinephrine; Pertussis Toxin; Propanolamines; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Signal Transduction; Sodium Fluoride; Sympathomimetics; Tritium; Virulence Factors, Bordetella; Weight Gain | 2001 |
The human delta opioid receptor activates G(i1)alpha more efficiently than G(o1)alpha.
Topics: Adenylyl Cyclases; Cell Line; Colforsin; Diprenorphine; Enkephalin, Leucine-2-Alanine; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Humans; Kinetics; Naltrexone; Polymerase Chain Reaction; Receptors, Opioid, delta; Recombinant Fusion Proteins; Recombinant Proteins; Transfection | 2001 |
The direct stimulation of Gi proteins by neuropeptide Y (NPY) in the rat left ventricle.
Topics: Animals; Antibodies; Arginine; Cell Membrane; Colforsin; Cyclic AMP; Drug Interactions; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Heart Ventricles; Hydrolysis; Kinetics; Male; Neuropeptide Y; Rats; Rats, Wistar; Ventricular Function, Left | 2002 |
Pertussis toxin-insensitive activation of the heterotrimeric G-proteins Gi/Go by the NG108-15 G-protein activator.
Topics: Animals; Brain; Carrier Proteins; Cattle; Cell Line; Cell Membrane; Colforsin; Glioma; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Isoproterenol; NAD; Neuroblastoma; Pertussis Toxin; Phosphorus Radioisotopes; Tumor Cells, Cultured | 2002 |
Tumor necrosis factor alpha stimulates adenylyl cyclase activity in human myometrial cells.
Topics: Adenylyl Cyclases; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Colforsin; Enzyme Activation; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine Triphosphate; Humans; Immunoblotting; Indomethacin; Myocytes, Smooth Muscle; Myometrium; Recombinant Proteins; Sodium Fluoride; Tumor Necrosis Factor-alpha | 2003 |
Serine phosphorylation negatively regulates RhoA in vivo.
Topics: 3T3 Cells; Alkyl and Aryl Transferases; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Gene Expression; Glutathione Transferase; GTP Phosphohydrolases; GTPase-Activating Proteins; Guanine Nucleotide Dissociation Inhibitors; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Mice; Mutagenesis; Phosphorylation; Recombinant Fusion Proteins; rho GTP-Binding Proteins; rho-Specific Guanine Nucleotide Dissociation Inhibitors; rhoA GTP-Binding Protein; Serine; Transfection | 2003 |
Amygdaloid D1 receptors are not linked to stimulation of adenylate cyclase.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Amygdala; Animals; Benzazepines; Binding Sites; Brain Chemistry; Calmodulin; Caudate Nucleus; Cell Membrane; Colforsin; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Fenoldopam; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Male; Microdissection; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Sulfur Isotopes; Tissue Distribution | 2003 |
Mutation of cysteine 214 in Gi1 alpha subunit abolishes its endogenous GTPase activity.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Alanine; Amino Acid Substitution; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cysteine; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Hydrolysis; Kinetics; Mutation; Pertussis Toxin; Protein Binding; Protein Subunits; RGS Proteins; Thermodynamics; Trypsin; Tryptophan | 2004 |
Entamoeba invadens contains the components of a classical adrenergic signaling system.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Entamoeba; Epinephrine; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Ligands; Pertussis Toxin; Receptors, Adrenergic; Signal Transduction | 2004 |
Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway.
Topics: Actins; Adenoviridae; Antigens, CD; Blotting, Western; Cadherins; Cell Adhesion; Cell Communication; Cell Line; Cell Line, Tumor; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelium, Vascular; Epoprostenol; Glutathione Transferase; GTPase-Activating Proteins; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Humans; Immunohistochemistry; Permeability; Plasmids; Protein Binding; Protein Structure, Tertiary; Protein Transport; rap1 GTP-Binding Proteins; Recombinant Proteins; Signal Transduction; Time Factors | 2005 |
[Molecular mechanisms of action of dendrons, containing 48-60 sequence of HIV-1 TAT-protein, on the functional activity of the adenylyl cyclase signaling systems].
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Colforsin; Enzyme Inhibitors; Gene Products, tat; GTP-Binding Proteins; Guanosine Triphosphate; HIV-1; Hormones; Male; Molecular Sequence Data; Mollusca; Muscle, Skeletal; Peptides; Protein Binding; Rats; Signal Transduction; tat Gene Products, Human Immunodeficiency Virus | 2004 |
Self-limitation of intravenous tocolysis with beta2-adrenergic agonists is mediated through receptor G protein uncoupling.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Colforsin; Female; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Pregnancy; Receptors, Adrenergic, beta-2; Tocolysis | 2005 |
A "locked-on," constitutively active mutant of the adenosine A1 receptor.
Topics: Adenosine; Animals; Binding, Competitive; Cell Line; Cell Membrane; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Mutation; Plasmids; Radioligand Assay; Receptor, Adenosine A1; Sodium; Sulfur Radioisotopes; Theophylline; Thiophenes; Transfection; Tritium; Xanthines | 2005 |
Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation.
Topics: Androstadienes; Animals; bcl-Associated Death Protein; Blotting, Western; Cell Count; Cell Proliferation; Chromones; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Gene Silencing; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Immunoprecipitation; Isoquinolines; Macrophages; Mice; Mice, Inbred C57BL; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; rap1 GTP-Binding Proteins; RNA Interference; RNA, Double-Stranded; Serine; Signal Transduction; Sulfonamides; Threonine; Thymidine; Time Factors; Up-Regulation; Wortmannin; X-Linked Inhibitor of Apoptosis Protein | 2005 |
Differential interactions of G-proteins and adenylyl cyclase with nucleoside 5'-triphosphates, nucleoside 5'-[gamma-thio]triphosphates and nucleoside 5'-[beta,gamma-imido]triphosphates.
Topics: Adenylyl Cyclases; Animals; Catalysis; Cell Line, Tumor; Colforsin; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Lymphoma; Models, Molecular; Protein Binding; Spodoptera | 2005 |
Functional expression of metabotropic GABAB receptors in primary cultures of astrocytes from rat cerebral cortex.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Astrocytes; Baclofen; Cell Membrane; Cells, Cultured; Cerebral Cortex; Colforsin; Gene Expression Regulation; Guanosine Triphosphate; Rats; Receptors, GABA-B; RNA, Messenger | 2006 |
Changed sensitivity of adenylate cyclase signaling system to biogenic amines and peptide hormones in tissues of starving rats.
Topics: Adenylyl Cyclases; Animals; Biogenic Amines; Brain; Bromocriptine; Colforsin; Guanosine Triphosphate; Heart; Isoproterenol; Male; Muscle, Skeletal; Myocardium; Rats; Rats, Wistar; Serotonin; Signal Transduction; Somatostatin; Starvation | 2007 |
Characterization of mouse heart adenylyl cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Catalysis; Cations, Divalent; Cell Line; Cell Membrane; Colforsin; Enzyme Inhibitors; Female; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoenzymes; Isoproterenol; Kinetics; Metoprolol; Mice; Mice, Inbred Strains; Myocardium; Protein Isoforms; Receptors, G-Protein-Coupled; Recombinant Proteins; Spodoptera | 2009 |
Differential interactions of the catalytic subunits of adenylyl cyclase with forskolin analogs.
Topics: Adenylyl Cyclases; Colforsin; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Binding; Protein Isoforms; Protein Subunits; Spectrometry, Fluorescence; Structure-Activity Relationship | 2009 |
Vascular endothelial-cadherin stabilizes at cell-cell junctions by anchoring to circumferential actin bundles through alpha- and beta-catenins in cyclic AMP-Epac-Rap1 signal-activated endothelial cells.
Topics: Actins; alpha Catenin; Animals; Antigens, CD; beta Catenin; Bridged Bicyclo Compounds, Heterocyclic; Cadherins; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Endothelial Cells; Fluorescence Recovery After Photobleaching; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Humans; Intercellular Junctions; Platelet Endothelial Cell Adhesion Molecule-1; rap1 GTP-Binding Proteins; Recombinant Fusion Proteins; RNA, Small Interfering; Signal Transduction; Thiazolidines | 2010 |
[Peptides derived from the third cytoplasmatic loop of serotonin 1B receptor subtype selectively inhibit serotonin signal transduction via a homologous receptor].
Topics: Adenylyl Cyclases; Animals; Brain; Colforsin; GTP-Binding Proteins; Guanosine Triphosphate; In Vitro Techniques; Male; Oligopeptides; Protein Binding; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction; Synaptosomes | 2010 |
Structural basis of adenylyl cyclase 9 activation.
Topics: Adenylyl Cyclases; Colforsin; Guanosine Triphosphate; Nucleotides; Signal Transduction | 2022 |