colforsin has been researched along with glutamic acid in 111 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (5.41) | 18.7374 |
| 1990's | 48 (43.24) | 18.2507 |
| 2000's | 44 (39.64) | 29.6817 |
| 2010's | 11 (9.91) | 24.3611 |
| 2020's | 2 (1.80) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
| Castrén, E; Hartikka, J; Lindholm, D; Thoenen, H; Zafra, F | 1 |
| Itano, Y; Kitamura, Y; Murayama, T; Nomura, Y | 1 |
| Bockaert, J; Curry, K; Homburger, V; Manzoni, O; Prezeau, L; Sladeczek, F | 1 |
| Haldeman, B; Kristensen, P; Mulvihill, E; Suzdak, PD; Thomsen, C | 1 |
| Mori-Okamoto, J; Namii, Y; Tatsuno, J | 1 |
| Hansson, E; Rönnbäck, L | 1 |
| Anderson, RJ; Breckon, R; Dillingham, MA; Dixon, BS; Kaehny, MM | 1 |
| Eklove, H; Webb, RA | 1 |
| Donaldson, J; Hill, SJ; Kendall, DA | 1 |
| Schwartz, EA | 1 |
| Mori-Okamoto, J; Tasuno, J | 1 |
| Gerber, G; Kangrga, I; Larew, JS; Randic, M; Ryu, PD | 1 |
| Dowling, JE; O'Brien, DR | 1 |
| Fastbom, J; Fredholm, BB; Lindgren, E | 1 |
| Baba, A; Iwata, H; Nishiuchi, Y; Tatsuno, T; Uemura, A | 1 |
| Soderling, TR; Tan, SE; Wenthold, RJ | 1 |
| Johnson, BG; Schoepp, DD | 2 |
| Barres, BA; Kaplan, MR; Meyer-Franke, A; Pfrieger, FW | 1 |
| Neale, JH; Saab, OH; Wroblewska, B; Wroblewski, JT | 1 |
| Barger, SW; Fiscus, RR; Hofmann, F; Mattson, MP; Ruth, P | 1 |
| Duvoisin, RM; Ramonell, K; Zhang, C | 1 |
| Arimura, A; Tatsuno, I | 1 |
| Barnabei, O; Lucchi, R; Poli, A; Traversa, U | 1 |
| Castillo, PE; Nicoll, RA; Weisskopf, MG; Zalutsky, RA | 1 |
| Gabellini, N; Manev, H; Manev, RM | 1 |
| Morris, M; Selley, DE; Sim, LJ; Tsai, KP | 1 |
| Bading, H; Ginty, DD; Greenberg, ME; Kornhauser, JM; Mayo, KE; Takahashi, JS; Thompson, MA | 1 |
| Fernández, MT; Gascón, S; Novelli, A; Torreblanca, A; Zitko, V | 1 |
| Duman, RS; Hartigan, DJ; Hayward, MD; Le, HN; Nestler, EJ; Vaccarino, FM | 1 |
| Suzdak, PD; Thomsen, C | 1 |
| Copolov, DL; Lim, AT; Yang, Z | 1 |
| Bond, A; Campbell, JB; Griffey, K; Howe, T; Johnson, BG; Lodge, D; Monn, JA; Paschal, JW; Salhoff, CR; Schoepp, DD; Spangle, LA; Tizzano, JP; Valli, MJ; Wright, RA | 1 |
| Alexander, SP; Kendall, DA; Neil, KE | 1 |
| Legutko, B; Pilc, A | 1 |
| Kerkerian-Le Goff, L; Nieoullon, A; Pisano, P; Samuel, D | 1 |
| Glitsch, M; Llano, I; Marty, A | 1 |
| Schmidt, KF | 1 |
| Cole, RL; Hyman, SE; Schwarzschild, MA | 1 |
| Djordjijevic, D; Epelbaum, J; Faivre-Bauman, A; Gardette, R; Kordon, C; Lanneau, C; Loudes, C; Viollet, C; Zhang, J | 1 |
| Neale, JH; Pshenichkin, S; Sullivan, SE; Surin, A; Wroblewska, B; Wroblewski, JT | 1 |
| Konradi, C | 1 |
| Ge, A; Ghosh, K; Hsiao, CL; Kowal, D; Tasse, R; Wardwell-Swanson, J | 1 |
| Ishihara, K; Mishima, HK; Saitoh, T; Sasa, M; Shiomi, H; Shoge, K; Tamura, Y | 1 |
| Burd, AL; El-Kouhen, R; Erickson, LJ; Law, PY; Loh, HH | 1 |
| Janz, R; Johnson, KM; Lonart, G; Südhof, TC | 1 |
| Bagley, EE; Christie, MJ; Vaughan, CW | 1 |
| Had-Aissouni, L; Kerkerian-Le Goff, L; Lortet, S; Masmejean, F; Pisano, P; Samuel, D | 1 |
| Battaglia, G; Bruno, V; Flor, PJ; Gasparini, F; Hess, SD; Inderbitzin, W; Johnson, EC; Kuhn, R; Laurie, D; Leonhardt, T; Lukic, S; Nicoletti, F; Portet, C; Sauer, D; Schmutz, M; Sommer, B; Urwyler, S; Varney, MA | 1 |
| Adachi, T; Nakao, S; Shingu, K; Shinomura, T | 1 |
| Carvalho, AL; Huganir, RL; Kameyama, K | 1 |
| Estevez, AY; O'Regan, MH; Phillis, JW; Song, D | 1 |
| Bouron, A | 1 |
| Bouron, A; Reuter, H | 1 |
| Chaudhari, N; Landin, AM; Roper, SD | 1 |
| Allaman, I; Magistretti, PJ; Pellerin, L | 1 |
| Fisone, G; Goiny, M; Goldstein, M; Haycock, J; Herrera-Marschitz, M; Hökfelt, T; Lindgren, N; Lindskog, M; Xu, ZQ | 1 |
| Kubo, Y; Miyashita, T | 1 |
| Alonso, G; Bockaert, J; Duchamp, F; Manzoni, OJ; Robbe, D | 1 |
| Evans, DI; Jones, RS; Woodhall, G | 1 |
| Grimaldi, M; Hampson, AJ | 1 |
| Maneuf, YP; McKnight, AT | 1 |
| Dunlop, J; Hediger, MA; Peng, JB; Trotti, D | 1 |
| Luján, R; Millán, C; Sánchez-Prieto, J; Shigemoto, R | 1 |
| Wang, GD; Zhuo, M | 1 |
| Elliott-Hunt, CR; Grammatopoulos, DK; Hillhouse, EW; Kazlauskaite, J; Wilde, GJ | 1 |
| Kirchgessner, AL; Ouedraogo, R; Tong, Q | 1 |
| Sandhu, JK; Sikorska, M; Walker, PR | 1 |
| Egli, RE; Schramm, NL; Winder, DG | 1 |
| Ariano, MA; Chao, SZ; Peterson, DA; Wolf, ME | 1 |
| Arnold, FJ; Bading, H; Hardingham, GE; Pokorska, A; Silvagno, F; Vanhoutte, P | 1 |
| Angelova, K; Puett, D | 1 |
| Duffy, SN; Nguyen, PV | 1 |
| Abaffy, T; Chaudhari, N; Trubey, KR | 1 |
| Boehm, S; Freissmuth, M; Just, H; Klinger, M; Korkhov, VM; Kudlacek, O; Nanoff, C; Pankevych, H; Vartian, N; Yang, Q | 1 |
| Battaglia, G; Beraudi, A; Cappuccio, I; Caricasole, A; D'Onofrio, M; Di Giorgi Gerevini, V; Nicoletti, F; Poli, A; Storto, M; Villani, L | 1 |
| Millán, C; Sánchez-Prieto, J; Torres, M | 1 |
| Fowler, CJ; Jacobsson, SO; Nilsson, O | 1 |
| Inoue, M; Kawamura, Y; Kudo, Y; Manita, S; Miyakawa, H; Nakamura, T | 1 |
| Barnes, NY; Parent, AT; Sisodia, SS; Taniguchi, Y; Thinakaran, G | 1 |
| Finlayson, PG; Shaikh, AG | 1 |
| Challiss, RA; Nahorski, SR; Warwick, HK | 1 |
| de Novellis, V; Maione, S; Marabese, I; Mariani, L; Palazzo, E; Rodella, L; Rossi, F; Siniscalco, D | 1 |
| Olsen, CM; Schramm-Sapyta, NL; Winder, DG | 1 |
| Ahlers, BA; Carl, LL; Cheung, JY; Moorman, JR; Mounsey, JP; Rothblum, LI; Song, J; Tucker, AL; Wang, J; Zhang, XQ | 1 |
| Glitsch, M | 1 |
| Delgado-García, JM; Negrete-Díaz, JV; Rodríguez-Moreno, A; Sihra, TS | 1 |
| Beltran-Parrazal, L; Brennan, KC; Charles, AC; de Vellis, J; Díaz-Muñoz, M; López-Valdés, HE | 1 |
| Defaix, A; Gautier, H; Grolleau, F; Lapied, B; Lavialle-Defaix, C | 1 |
| Fujiyoshi, Y; Hige, T; Takahashi, T | 1 |
| Fukazawa, Y; Momiyama, T | 1 |
| Nakamichi, N; Ogura, M; Taniura, H; Yoneda, Y | 1 |
| López de Armentia, M; Sah, P | 1 |
| Cho, YW; Hahm, ET; Lee, CH; Lee, JJ | 1 |
| Kawahara, K; Kosugi, T; Mioka, T; Tanaka, M; Yamada, T | 1 |
| Genlain, M; Godaux, E; Ris, L | 1 |
| Kubo, Y; Tateyama, M | 1 |
| Bartolomé-Martín, D; Ladera, C; Martín, R; Sánchez-Prieto, J; Torres, M | 1 |
| Barrionuevo, G; Card, JP; Cosgrove, KE; Galván, EJ; Mauna, JC; Meriney, SD; Thiels, E | 1 |
| Carriba, P; Galea, E; Lichtenstein, MP; Masgrau, R; Pardo, L; Parra-Damas, A; Pujol, A; Saura, CA | 1 |
| Colbert, CM; Eskin, A; Pita-Almenar, JD; Zou, S | 1 |
| Casazza, S; Di Prisco, S; Merega, E; Milanese, M; Pistoia, V; Pittaluga, A; Raffaghello, L; Summa, M; Uccelli, A | 1 |
| Aguado, C; Alvarez, AM; Bartolomé-Martín, D; Ciruela, F; Ferrero, JJ; Godino, MC; Luján, R; Ramírez-Franco, J; Sánchez-Prieto, J; Torres, M | 1 |
| DiRaddo, JO; Grajkowska, E; Hathaway, HA; Liotta, DC; Miller, EJ; Wolfe, BB; Wroblewska, B; Wroblewski, JT | 1 |
| Cisneros, IE; Ghorpade, A | 1 |
| Chang, JC; Chang, WP; Chen, IM; Cheng, JK; Chiu, HF; Lin, CH; Lin, CI; Lin, PH | 1 |
| Doré, S; Mohan, S; Narumiya, S | 1 |
| Hirasawa, M; Muram, S; Rowe, TM | 1 |
| Breustedt, J; Bruentgens, F; Dvorzhak, A; Maglione, M; Orlando, M; Rost, BR; Schmitz, D; Sigrist, SJ | 1 |
| Dai, S; Guo, Z; He, X; Hu, Z; Jiao, Z; Lu, M; Wang, H; Xu, D | 1 |
111 other study(ies) available for colforsin and glutamic acid
| Article | Year |
|---|---|
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Astrocytes; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cytokines; Glutamates; Glutamic Acid; Growth Substances; Hippocampus; Ionomycin; Isoquinolines; Kainic Acid; Kinetics; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Nifedipine; Norepinephrine; Piperazines; Potassium; Protein Kinase Inhibitors; Quisqualic Acid; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Glutamate inhibits adenylate cyclase activity in dispersed rat hippocampal cells directly via an N-methyl-D-aspartate-like metabotropic receptor.
Topics: Adenylyl Cyclase Inhibitors; Amino Acids; Animals; Colforsin; Cyclic AMP; Glutamates; Glutamic Acid; GTP-Binding Proteins; Hippocampus; Rats; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical | 1992 |
Characterization of a metabotropic glutamate receptor: direct negative coupling to adenylyl cyclase and involvement of a pertussis toxin-sensitive G protein.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Alanine; Alkaloids; Animals; Cell Membrane; Cells, Cultured; Colforsin; Corpus Striatum; Cycloleucine; Glutamates; Glutamic Acid; GTP-Binding Proteins; In Vitro Techniques; Mice; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Protein Kinase C; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Signal Transduction; Staurosporine; Virulence Factors, Bordetella | 1992 |
L-2-amino-4-phosphonobutyrate (L-AP4) is an agonist at the type IV metabotropic glutamate receptor which is negatively coupled to adenylate cyclase.
Topics: Adenylyl Cyclases; Aminobutyrates; Animals; Cells, Cultured; Colforsin; Cricetinae; Cyclic AMP; Glutamates; Glutamic Acid; Kidney; Receptors, Glutamate | 1992 |
Subtypes of adrenergic receptors and intracellular mechanisms involved in modulatory effects of noradrenaline on glutamate.
Topics: Acebutolol; Albuterol; Animals; Cells, Cultured; Cerebellum; Chick Embryo; Clonidine; Colforsin; Electric Conductivity; Ethanolamines; Glutamates; Glutamic Acid; Isoproterenol; Membrane Potentials; Neurons; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tolazoline; Yohimbine | 1991 |
Receptor regulation of the glutamate, GABA and taurine high-affinity uptake into astrocytes in primary culture.
Topics: Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biological Transport; Cells, Cultured; Cerebral Cortex; Cholera Toxin; Colforsin; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Isoproterenol; Kinetics; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin; Taurine; Virulence Factors, Bordetella | 1991 |
Histidine regulation of cyclic AMP metabolism in cultured renal epithelial LLC-PK1 cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Arginine Vasopressin; Aspartic Acid; Cells, Cultured; Colforsin; Cyclic AMP; Epithelial Cells; Epithelium; Glutamates; Glutamic Acid; Histidine; Imidazoles; Indomethacin; Kidney; Swine | 1990 |
The effect of L-glutamate and related agents on adenylate cyclase in the cestode Hymenolepis diminuta.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Glutamates; Glutamic Acid; Guanylate Cyclase; Hymenolepiasis; Hymenolepis; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Serotonin; Virulence Factors, Bordetella | 1991 |
Discriminatory effects of forskolin and EGTA on the indirect cyclic AMP responses to histamine, noradrenaline, 5-hydroxytryptamine, and glutamate in guinea-pig cerebral cortical slices.
Topics: Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Egtazic Acid; Glutamates; Glutamic Acid; Guinea Pigs; Histamine; In Vitro Techniques; Inositol Phosphates; Neurotransmitter Agents; Norepinephrine; Phorbol 12,13-Dibutyrate; Serotonin | 1990 |
Synaptic transmission in amphibian retinae during conditions unfavourable for calcium entry into presynaptic terminals.
Topics: Ambystoma; Animals; Bufo marinus; Calcium; Cobalt; Colforsin; Glutamates; Glutamic Acid; Histidine; In Vitro Techniques; Ion Channels; Retina; Synapses; Synaptic Transmission; Tetraethylammonium; Tetraethylammonium Compounds | 1986 |
Participation of cyclic adenosine monophosphate and beta-adrenergic receptors in the facilitatory effect of noradrenaline on the response of cultured cerebellar neurons to glutamate.
Topics: Action Potentials; Animals; Bucladesine; Cells, Cultured; Cerebellum; Chick Embryo; Colforsin; Cyclic AMP; Glutamates; Glutamic Acid; Isoproterenol; Norepinephrine; Receptors, Adrenergic, beta; Second Messenger Systems; Theophylline | 1989 |
Multiple effects of phorbol esters in the rat spinal dorsal horn.
Topics: Action Potentials; Amino Acids; Animals; Aspartic Acid; Calcium; Colforsin; Drug Synergism; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Phorbol Esters; Rats; Rats, Inbred Strains; Sodium; Spinal Cord; Synapses; Synaptic Transmission | 1989 |
Dopaminergic regulation of GABA release from the intact goldfish retina.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Cyprinidae; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Goldfish; In Vitro Techniques; Retina; Synaptic Transmission | 1985 |
Effects of N-ethylmaleimide and forskolin on glutamate release from rat hippocampal slices. Evidence that prejunctional adenosine receptors are linked to N-proteins, but not to adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Colforsin; Ethylmaleimide; Glutamates; Glutamic Acid; GTP-Binding Proteins; Hippocampus; Male; Phenylisopropyladenosine; Protein Binding; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Neurotransmitter; Receptors, Purinergic; Rolipram | 1986 |
Inhibition by forskolin of excitatory amino acid-induced accumulation of cyclic AMP in guinea pig hippocampal slices.
Topics: Adenosine; Amino Acids; Animals; Aspartic Acid; Chlorides; Colforsin; Cyclic AMP; Cysteine; Drug Interactions; Ethylmaleimide; Glutamates; Glutamic Acid; Guanosine Triphosphate; Guinea Pigs; Hippocampus; Histamine; Male; N-Methylaspartate; Neurotransmitter Agents; Veratridine | 1988 |
Phosphorylation of AMPA-type glutamate receptors by calcium/calmodulin-dependent protein kinase II and protein kinase C in cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Colforsin; Cyclic AMP-Dependent Protein Kinases; Glutamates; Glutamic Acid; Glycine; Hippocampus; Intracellular Signaling Peptides and Proteins; Ionomycin; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Phosphorylation; Protein Kinase C; Proteins; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tetradecanoylphorbol Acetate | 1994 |
Metabotropic glutamate receptor modulation of cAMP accumulation in the neonatal rat hippocampus.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Deaminase; Animals; Animals, Newborn; Colforsin; Cyclic AMP; Cycloleucine; Female; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Neurotoxins; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1993 |
Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture.
Topics: Animals; Astrocytes; Brain-Derived Neurotrophic Factor; Cell Count; Cell Division; Cell Survival; Cells, Cultured; Ciliary Neurotrophic Factor; Colforsin; Cyclic AMP; Electrophysiology; Glutamic Acid; Humans; Insulin-Like Growth Factor I; Mice; Nerve Tissue Proteins; Oligodendroglia; Potassium; Rats; Retina; Retinal Ganglion Cells; Signal Transduction | 1995 |
N-acetylaspartylglutamate inhibits forskolin-stimulated cyclic AMP levels via a metabotropic glutamate receptor in cultured cerebellar granule cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Cerebellum; Colforsin; Cyclic AMP; Cycloleucine; Dipeptides; Glutamates; Glutamic Acid; Granulocytes; Inositol Phosphates; Receptors, Glutamate | 1993 |
Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of beta-amyloid precursor.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Glutamic Acid; Hippocampus; Neurons; Rats | 1995 |
A novel metabotropic glutamate receptor expressed in the retina and olfactory bulb.
Topics: Amino Acid Sequence; Aminobutyrates; Animals; Base Sequence; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; DNA Primers; DNA, Complementary; Gene Expression; Gene Library; Glutamic Acid; In Situ Hybridization; Mice; Molecular Sequence Data; Multigene Family; Olfactory Bulb; Polymerase Chain Reaction; Receptors, Metabotropic Glutamate; Recombinant Proteins; Retina; RNA, Messenger; Sequence Homology, Amino Acid; Transfection | 1995 |
Pituitary adenylate cyclase-activating polypeptide (PACAP) mobilizes intracellular free calcium in cultured rat type-2, but not type-1, astrocytes.
Topics: Animals; Astrocytes; Bucladesine; Calcium; Cell Communication; Cells, Cultured; Colforsin; Cyclic AMP; Fura-2; Glutamic Acid; Neurons; Neuropeptides; Neurotransmitter Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats | 1994 |
Functional adenosine A1 receptors in goldfish brain: regional distribution and inhibition of K(+)-evoked glutamate release from cerebellar slices.
Topics: Adenosine; Adenylyl Cyclases; Amino Acids; Animals; Calcium; Cerebellum; Colforsin; Cyclic AMP; Glutamates; Glutamic Acid; Goldfish; In Vitro Techniques; Membranes; Potassium; Receptors, Purinergic P1; Theophylline | 1994 |
Mediation of hippocampal mossy fiber long-term potentiation by cyclic AMP.
Topics: Animals; Calcium; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Indoles; Isoquinolines; Long-Term Potentiation; Models, Biological; Nerve Fibers; Presynaptic Terminals; Pyramidal Cells; Pyrroles; Sulfonamides; Synaptic Transmission | 1994 |
Is the heterologous expression of metabotropic glutamate receptors (mGluRs) an appropriate method to study the mGluR function? Experience with human embryonic kidney 293 cells transfected with mGluR1.
Topics: Alternative Splicing; Blotting, Northern; Calcium; Cell Division; Cell Line; Cell Survival; Colforsin; Cycloleucine; Embryo, Mammalian; Gene Expression; Glutamic Acid; Humans; Inositol Phosphates; Kidney; Neurotoxins; Pertussis Toxin; Receptors, Metabotropic Glutamate; RNA, Messenger; Thymidine; Transfection; Virulence Factors, Bordetella | 1994 |
Calcium and cAMP mediated stimulation of Fos in cultured hypothalamic tyrosine hydroxylase-immunoreactive neurons.
Topics: Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Glutamic Acid; Hypothalamus; Immunohistochemistry; Neurons; Potassium Chloride; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 1994 |
Pharmacology of metabotropic glutamate receptor inhibition of cyclic AMP formation in the adult rat hippocampus.
Topics: Alanine; Animals; Colforsin; Cyclic AMP; Cycloleucine; Glutamates; Glutamic Acid; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1993 |
Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock.
Topics: Amino Acid Sequence; Animals; Base Sequence; Circadian Rhythm; Colforsin; Cricetinae; Cyclic AMP Response Element-Binding Protein; Darkness; Gene Expression Regulation; Genes, fos; Glutamates; Glutamic Acid; Light; Molecular Sequence Data; PC12 Cells; Phosphorylation; Potassium Chloride; Suprachiasmatic Nucleus | 1993 |
Neurotoxic effect of okadaic acid, a seafood-related toxin, on cultured cerebellar neurons.
Topics: Animals; Cell Death; Cells, Cultured; Cerebellum; Colforsin; Ethers, Cyclic; Glutamates; Glutamic Acid; Kainic Acid; Marine Toxins; Models, Neurological; Neurons; Neurotoxins; Okadaic Acid; Phosphoprotein Phosphatases; Rats; Shellfish; Tetradecanoylphorbol Acetate | 1993 |
Induction of immediate early genes by cyclic AMP in primary cultures of neurons from rat cerebral cortex.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Bucladesine; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; DNA-Binding Proteins; Dopamine Agents; Early Growth Response Protein 1; Ergolines; Gene Expression Regulation; Genes, fos; Genes, jun; Glutamates; Glutamic Acid; Immediate-Early Proteins; Immunohistochemistry; Kinetics; Neuroglia; Neurons; Quinpirole; Rats; RNA, Messenger; Second Messenger Systems; Transcription Factors; Vasoactive Intestinal Peptide | 1993 |
Serine-O-phosphate has affinity for type IV, but not type I, metabotropic glutamate receptor.
Topics: Animals; Cell Line; Colforsin; Cricetinae; Culture Media; Cyclic AMP; Glutamates; Glutamic Acid; Hydrolysis; Kidney; Phosphatidylinositols; Phosphoserine; Receptors, Metabotropic Glutamate; Stereoisomerism | 1993 |
Glutamate enhances the adenylyl cyclase-cAMP system-induced beta-endorphin secretion and POMC mRNA expression in rat hypothalamic neurons in culture: NMDA receptor-mediated modulation.
Topics: Adenylyl Cyclases; Animals; beta-Endorphin; Blotting, Northern; Cells, Cultured; Colforsin; Cyclic AMP; Excitatory Amino Acid Agonists; Glutamic Acid; Hypothalamus; Neurons; Pro-Opiomelanocortin; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Stimulation, Chemical | 1995 |
Synthesis of the four isomers of 4-aminopyrrolidine-2,4-dicarboxylate: identification of a potent, highly selective, and systemically-active agonist for metabotropic glutamate receptors negatively coupled to adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Anticonvulsants; Cerebral Cortex; Colforsin; Cyclic AMP; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Hydrogen Bonding; Limbic System; Mice; Models, Molecular; Molecular Structure; Proline; Rats; Receptors, Metabotropic Glutamate; Seizures; Spinal Cord; Stereoisomerism | 1996 |
Coupling of metabotropic glutamate receptors to phosphoinositide mobilisation and inhibition of cyclic AMP generation in the guinea-pig cerebellum.
Topics: 2-Chloroadenosine; Animals; Cerebellum; Colforsin; Cyclic AMP; Cycloleucine; Female; Glutamic Acid; Glycine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Phosphatidylinositols; Receptors, Metabotropic Glutamate; Resorcinols | 1996 |
The influence of prolonged antidepressant treatment on the changes in cyclic AMP accumulation induced by excitatory amino acids in rat cerebral cortical slices.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Cerebral Cortex; Colforsin; Cyclic AMP; Drug Interactions; Electroshock; Glutamic Acid; Ibotenic Acid; Imipramine; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Wistar; Time Factors | 1995 |
Activation of the adenylate cyclase-dependent protein kinase pathway increases high affinity glutamate uptake into rat striatal synaptosomes.
Topics: Adenylyl Cyclases; Animals; Colforsin; Corpus Striatum; Dose-Response Relationship, Drug; Female; Glutamic Acid; Okadaic Acid; Protein Kinases; Rats; Rats, Wistar; Synaptosomes | 1996 |
Glutamate as a candidate retrograde messenger at interneurone-Purkinje cell synapses of rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Benzoates; Colforsin; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Interneurons; Kinetics; Presynaptic Terminals; Purkinje Cells; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission; Tetrodotoxin | 1996 |
Protein kinase C does not mediate the dopamine-dependent modulation of glutamate receptors in retinal horizontal cells of the perch (Perca fluviatilis).
Topics: Animals; Cell Culture Techniques; Colforsin; Dopamine; Dose-Response Relationship, Drug; Glutamic Acid; Membrane Potentials; Patch-Clamp Techniques; Perches; Protein Kinase C; Receptors, Glutamate; Retina | 1996 |
Glutamate, but not dopamine, stimulates stress-activated protein kinase and AP-1-mediated transcription in striatal neurons.
Topics: Activating Transcription Factor 2; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP Response Element-Binding Protein; Dopamine; Gene Expression Regulation, Enzymologic; Glutamic Acid; JNK Mitogen-Activated Protein Kinases; Leucine Zippers; Mitogen-Activated Protein Kinases; Neostriatum; Neurons; Protein Binding; RNA, Messenger; Signal Transduction; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic | 1997 |
Distinct patterns of expression and physiological effects of sst1 and sst2 receptor subtypes in mouse hypothalamic neurons and astrocytes in culture.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Astrocytes; Autoradiography; Binding Sites; Cells, Cultured; Colforsin; Fetus; Gene Expression Regulation, Developmental; Glutamic Acid; Hormones; Hypothalamus; Iodine Radioisotopes; Mice; Neurons; Octreotide; Patch-Clamp Techniques; Peptide Fragments; Polymerase Chain Reaction; Receptors, Somatostatin; RNA, Messenger; Sensitivity and Specificity; Somatostatin | 1997 |
N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells.
Topics: Animals; Calcium; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cycloleucine; Dipeptides; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Fetus; Glutamic Acid; Histamine H1 Antagonists; Humans; Hydrolysis; Kidney; Neuropeptides; Neuroprotective Agents; Phosphates; Rats; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Transfection | 1997 |
The molecular basis of dopamine and glutamate interactions in the striatum.
Topics: Animals; Cells, Cultured; Colforsin; Corpus Striatum; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Neurons; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Second Messenger Systems; Transcription, Genetic | 1998 |
A [35S]GTPgammaS binding assessment of metabotropic glutamate receptor standards in Chinese hamster ovary cell lines expressing the human metabotropic receptor subtypes 2 and 4.
Topics: Animals; CHO Cells; Colforsin; Cricetinae; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Metabotropic Glutamate; Sulfur Radioisotopes | 1998 |
Protective effects of vasoactive intestinal peptide against delayed glutamate neurotoxicity in cultured retina.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cell Survival; Cells, Cultured; Colforsin; Cyclic AMP; Glutamic Acid; Membrane Potentials; Neurotoxins; Patch-Clamp Techniques; Rats; Rats, Wistar; Retina; Vasoactive Intestinal Peptide | 1998 |
Identification of serine 356 and serine 363 as the amino acids involved in etorphine-induced down-regulation of the mu-opioid receptor.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Cell Line; Colforsin; Cyclic AMP; Diprenorphine; Down-Regulation; Etorphine; Glutamic Acid; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Receptors, Opioid, mu; Recombinant Fusion Proteins; Sequence Deletion; Serine; Transfection | 1998 |
Mechanism of action of rab3A in mossy fiber LTP.
Topics: Animals; Colforsin; Glutamic Acid; GTP-Binding Proteins; Long-Term Potentiation; Mice; Mice, Knockout; Mossy Fibers, Hippocampal; Presynaptic Terminals; rab3 GTP-Binding Proteins; Rats; Synaptosomes | 1998 |
Inhibition by adenosine receptor agonists of synaptic transmission in rat periaqueductal grey neurons.
Topics: Action Potentials; Adenosine; Animals; Colforsin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1999 |
Effects of PKA and PKC modulators on high affinity glutamate uptake in primary neuronal cell cultures from rat cerebral cortex.
Topics: Alkaloids; Animals; Benzophenanthridines; Biological Transport; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Fetus; Glutamic Acid; Isoquinolines; Kinetics; Neurons; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate | 1999 |
(R,S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo.
Topics: Animals; Anticonvulsants; Brain; Cell Line; Cell Membrane; Colforsin; Corpus Striatum; Cyclic AMP; Electroshock; Glutamic Acid; Glycine; Humans; Kinetics; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Neuroprotective Agents; Phosphatidylinositols; Protein Isoforms; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Recombinant Proteins; Second Messenger Systems; Seizures; Structure-Activity Relationship | 1999 |
Clonidine inhibits and phorbol acetate activates glutamate release from rat spinal synaptoneurosomes.
Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Animals; Calcium; Clonidine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Glutamate Dehydrogenase; Glutamic Acid; In Vitro Techniques; Male; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Spectrometry, Fluorescence; Spinal Cord; Synaptosomes; Tetradecanoylphorbol Acetate | 1999 |
Characterization of phosphorylation sites on the glutamate receptor 4 subunit of the AMPA receptors.
Topics: Amino Acid Sequence; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Epithelial Cells; Glutamic Acid; Humans; Kidney; Molecular Sequence Data; Mutagenesis; Phosphorylation; Protein Kinase C; Receptors, AMPA; Synaptic Transmission; Threonine; Transfection | 1999 |
Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases.
Topics: Acetophenones; Alanine; Amino Acids; Animals; Arachidonic Acids; Aspartic Acid; Brain Edema; Cerebral Cortex; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dimethyl Sulfoxide; Enzyme Inhibitors; Estrenes; Ethanolamines; Fatty Acids, Unsaturated; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hypotonic Solutions; Male; Osmotic Pressure; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Protein Kinase C; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Serine; Solvents; Taurine; Water-Electrolyte Balance | 1999 |
Adenosine suppresses protein kinase A- and C-induced enhancement of glutamate release in the hippocampus.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylyl Cyclases; Animals; Animals, Newborn; Carbachol; Carcinogens; Cells, Cultured; Cholinergic Agonists; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dopamine Agonists; Enzyme Activation; Excitatory Postsynaptic Potentials; Exocytosis; Glutamic Acid; Hippocampus; Patch-Clamp Techniques; Protein Kinase C; Rats; Synaptic Transmission; Tetradecanoylphorbol Acetate | 1999 |
The D1 dopamine receptor agonist SKF-38393 stimulates the release of glutamate in the hippocampus.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Colforsin; Dopamine Agonists; Glutamic Acid; Hippocampus; Rats; Receptors, Dopamine D1; Tetrodotoxin | 1999 |
A metabotropic glutamate receptor variant functions as a taste receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Chemoreceptor Cells; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; DNA, Complementary; Dose-Response Relationship, Drug; Glutamic Acid; GTP-Binding Proteins; Molecular Sequence Data; Organ Specificity; Polymerase Chain Reaction; Propionates; Protein Isoforms; Rats; Receptors, Metabotropic Glutamate; RNA, Messenger; Taste; Taste Buds; Transfection | 2000 |
Protein targeting to glycogen mRNA expression is stimulated by noradrenaline in mouse cortical astrocytes.
Topics: Animals; Astrocytes; Bucladesine; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Colforsin; Gene Expression; Glutamic Acid; Glycogen; Insulin; Intracellular Signaling Peptides and Proteins; Mice; Norepinephrine; Receptors, Adrenergic, beta-1; RNA, Messenger; Vasoactive Intestinal Peptide | 2000 |
Regulation of tyrosine hydroxylase activity and phosphorylation at Ser(19) and Ser(40) via activation of glutamate NMDA receptors in rat striatum.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antibody Specificity; Catalytic Domain; Caudate Nucleus; Colforsin; Dihydroxyphenylalanine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Okadaic Acid; Oxidopamine; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Sympatholytics; Tyrosine 3-Monooxygenase | 2000 |
Extracellular Ca2+ sensitivity of mGluR1alpha induces an increase in the basal cAMP level by direct coupling with Gs protein in transfected CHO cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Calcium; Cell Size; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Fluorescent Dyes; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Isoquinolines; MAP Kinase Signaling System; Protein Kinase C; Receptors, Metabotropic Glutamate; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases | 2000 |
Localization and mechanisms of action of cannabinoid receptors at the glutamatergic synapses of the mouse nucleus accumbens.
Topics: Action Potentials; Afferent Pathways; Animals; Calcium Channel Blockers; Cannabinoids; Cerebellar Cortex; Colforsin; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Neural Inhibition; Nucleus Accumbens; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Presynaptic Terminals; Receptors, Cannabinoid; Receptors, Drug; Receptors, Glutamate; Synapses; Synaptic Transmission; Ultrasonography | 2001 |
Differential actions of PKA and PKC in the regulation of glutamate release by group III mGluRs in the entorhinal cortex.
Topics: Adenine; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclopentanes; Entorhinal Cortex; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; In Vitro Techniques; Indoles; Isoquinolines; Male; Maleimides; Presynaptic Terminals; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Sulfonamides; Tricarboxylic Acids | 2001 |
Cannabinoid receptor activation and elevated cyclic AMP reduce glutamate neurotoxicity.
Topics: Animals; Bucladesine; Calcium; Calcium Channels; Cannabinoids; Colforsin; Cyclic AMP; Cyclohexanols; Glutamic Acid; Neurotoxins; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug | 2001 |
Block by gabapentin of the facilitation of glutamate release from rat trigeminal nucleus following activation of protein kinase C or adenylyl cyclase.
Topics: Acetates; Adenylyl Cyclases; Amines; Analgesics; Animals; Colforsin; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Enzyme Activation; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Potassium; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Trigeminal Nuclei; Tritium | 2001 |
Inhibition of the glutamate transporter EAAC1 expressed in Xenopus oocytes by phorbol esters.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Transport System X-AG; Animals; Carcinogens; Carrier Proteins; Cell Membrane; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Indoles; Maleimides; Membrane Potentials; Oocytes; Phorbols; Protein Kinase C; RNA, Complementary; Symporters; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured; Xenopus laevis | 2001 |
The inhibition of glutamate release by metabotropic glutamate receptor 7 affects both [Ca2+]c and cAMP: evidence for a strong reduction of Ca2+ entry in single nerve terminals.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Glutamates; Glutamic Acid; Immunohistochemistry; Male; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Signal Transduction; Synaptosomes; Time Factors | 2002 |
Synergistic enhancement of glutamate-mediated responses by serotonin and forskolin in adult mouse spinal dorsal horn neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenylyl Cyclases; Animals; Colforsin; Drug Synergism; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Culture Techniques; Posterior Horn Cells; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Serotonin; Valine | 2002 |
Potential signalling pathways underlying corticotrophin-releasing hormone-mediated neuroprotection from excitotoxicity in rat hippocampus.
Topics: Animals; Cell Death; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Enzyme Inhibitors; Flavonoids; Glutamic Acid; Hippocampus; In Situ Hybridization, Fluorescence; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Neurotoxins; Organ Culture Techniques; Proto-Oncogene Proteins c-jun; Rats | 2002 |
Localization and function of group III metabotropic glutamate receptors in rat pancreatic islets.
Topics: Animals; Benzoates; Cell Membrane; Colforsin; Cyclic AMP; Cytoplasmic Granules; DNA Primers; Excitatory Amino Acid Antagonists; Female; Gene Expression; Glucagon; Glutamic Acid; Glycine; Islets of Langerhans; Microscopy, Immunoelectron; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Synaptophysin; Tissue Distribution | 2002 |
Characterization of astrocytes derived from human NTera-2/D1 embryonal carcinoma cells.
Topics: Astrocytes; Cell Differentiation; Cell Division; Cell Lineage; Colforsin; Embryonal Carcinoma Stem Cells; Glutamate-Ammonia Ligase; Glutamic Acid; Homeostasis; Humans; In Vitro Techniques; Intermediate Filament Proteins; Neoplastic Stem Cells; Nerve Degeneration; Nerve Tissue Proteins; Nestin; Teratocarcinoma; Tumor Cells, Cultured | 2002 |
LTP in the mouse nucleus accumbens is developmentally regulated.
Topics: Age Factors; Animals; Colforsin; Cyclic AMP; Electrophysiology; Evoked Potentials; Glutamic Acid; Long-Term Potentiation; Magnesium; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Organ Culture Techniques; Receptors, N-Methyl-D-Aspartate; Substance-Related Disorders; Synapses | 2002 |
D1 dopamine receptor stimulation increases GluR1 surface expression in nucleus accumbens neurons.
Topics: Animals; Benzazepines; Cell Membrane; Cells, Cultured; Colforsin; Dopamine Agonists; Dopamine Antagonists; Glutamic Acid; Interneurons; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2002 |
Synaptic activity induces signalling to CREB without increasing global levels of cAMP in hippocampal neurons.
Topics: Action Potentials; Animals; Calcium; Calcium Signaling; Cell Nucleus; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; GABA Antagonists; Glutamic Acid; Hippocampus; Neurons; Phosphorylation; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Long-Evans; Signal Transduction; Synaptic Transmission | 2003 |
Differential responses of an invariant region in the ectodomain of three glycoprotein hormone receptors to mutagenesis and assay conditions.
Topics: Adenylyl Cyclases; Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Colforsin; COS Cells; Cyclic AMP; Glutamic Acid; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Radioimmunoassay; Rats; Receptors, FSH; Receptors, LH; Receptors, Thyrotropin; Transfection | 2002 |
Postsynaptic application of a peptide inhibitor of cAMP-dependent protein kinase blocks expression of long-lasting synaptic potentiation in hippocampal neurons.
Topics: Animals; Carrier Proteins; Cells, Cultured; Chromosome Pairing; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electric Conductivity; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Intracellular Signaling Peptides and Proteins; Kinetics; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Peptide Fragments; Pyramidal Cells; Synaptic Transmission; Thionucleotides | 2003 |
Adenylyl cyclase expression and modulation of cAMP in rat taste cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Epithelium; Glutamic Acid; Isoenzymes; Male; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Taste; Taste Buds; Transducin | 2003 |
The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenylyl Cyclases; Animals; Benzamides; Binding, Competitive; Cell Cycle; Cell Membrane; Cofilin 1; Colforsin; Cyclic AMP; Cytoskeletal Proteins; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enzyme Activation; Gene Expression; Glutamic Acid; Humans; Membrane Potentials; Patch-Clamp Techniques; PC12 Cells; Pertussis Toxin; Phenethylamines; Phosphodiesterase Inhibitors; Phosphoproteins; Propionates; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrrolidines; Quinpirole; Radioligand Assay; Rats; Receptors, Dopamine D2; Receptors, Purinergic P1; Thionucleotides; Transfection; Triazines; Triazoles; Xenopus Proteins | 2003 |
Group II metabotropic glutamate receptors regulate the vulnerability to hypoxic brain damage.
Topics: Animals; Apoptosis; Blotting, Western; Brain; Colforsin; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fishes; Glutamic Acid; Goldfish; Hypoxia, Brain; In Vitro Techniques; Male; Proline; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Species Specificity | 2003 |
Co-activation of PKA and PKC in cerebrocortical nerve terminals synergistically facilitates glutamate release.
Topics: Animals; Brain Chemistry; Calcium Channels; Cerebral Cortex; Colforsin; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Enzyme Activation; Enzyme Activators; Glutamic Acid; Male; Phorbol Esters; Presynaptic Terminals; Protein Kinase C; Rats; Rats, Wistar; Synaptosomes; Tetrodotoxin; Up-Regulation | 2003 |
Cannabinoid CB1 receptor activation does not prevent the toxicity of glutamate towards embryonic chick telencephalon primary cultures.
Topics: Animals; Arachidonic Acids; Cannabinoids; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Cyclohexanols; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Endocannabinoids; Excitatory Amino Acid Antagonists; Glutamic Acid; L-Lactate Dehydrogenase; Models, Animal; Neurons; Pipecolic Acids; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Telencephalon | 2003 |
Glutamate release increases during mossy-CA3 LTP but not during Schaffer-CA1 LTP.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Calcium; Colforsin; Coloring Agents; Cyclopropanes; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Magnesium; Male; Mossy Fibers, Hippocampal; Neuroglia; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |
Presenilin attenuates receptor-mediated signaling and synaptic function.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Carbamates; Carbazoles; Cell Adhesion Molecules; Cell Line, Tumor; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DCC Receptor; Dipeptides; Endopeptidases; Excitatory Postsynaptic Potentials; Genes, DCC; Glutamic Acid; Indoles; Lidocaine; Membrane Proteins; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurites; Neuroblastoma; Neurons; Piperazines; Presenilin-1; Protein Processing, Post-Translational; Pyrroles; Quinoxalines; Rats; Receptors, Cell Surface; Recombinant Fusion Proteins; Second Messenger Systems; Synaptic Transmission; Transfection; Tumor Suppressor Proteins | 2005 |
Excitability of auditory brainstem neurons, in vivo, is increased by cyclic-AMP.
Topics: Acoustic Stimulation; Adenylyl Cyclases; Analysis of Variance; Animals; Auditory Perception; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; Ion Channels; Male; Neurons; Olivary Nucleus; Pyrimidines; Rats; Rats, Long-Evans | 2005 |
Group I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to cyclic AMP response element binding protein (CREB) through a common Ca2+ - and protein kinase C-dependent pathway.
Topics: Analysis of Variance; Animals; Blotting, Western; Calcium; Calcium Channel Blockers; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Fura-2; Gene Expression Regulation; Glutamic Acid; Indoles; Ionomycin; Ionophores; Isopropyl Thiogalactoside; Pertussis Toxin; Phosphorylation; Protein Kinase C; Quisqualic Acid; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Signal Transduction; Teprotide; Time Factors | 2005 |
Differential roles of mGlu8 receptors in the regulation of glutamate and gamma-aminobutyric acid release at periaqueductal grey level.
Topics: Alanine; Aminobutyrates; Analysis of Variance; Animals; Benzoates; Colforsin; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Immunohistochemistry; Isoquinolines; Male; Microdialysis; Microscopy, Immunoelectron; Periaqueductal Gray; Phosphoserine; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Sulfonamides; Time Factors | 2005 |
Cocaine self-administration reduces excitatory responses in the mouse nucleus accumbens shell.
Topics: Animals; Behavior, Animal; Cocaine; Colforsin; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Evoked Potentials; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Self Administration; Time Factors | 2006 |
Phospholemman inhibition of the cardiac Na+/Ca2+ exchanger. Role of phosphorylation.
Topics: Adenosine Triphosphatases; Alanine; Animals; Calsequestrin; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP-Dependent Protein Kinases; Glutamic Acid; Humans; Immunoblotting; Ions; Membrane Proteins; Mice; Mice, Knockout; Muscle Cells; Muscles; Mutation; Myocardium; Phosphoproteins; Phosphorylation; Serine; Sodium; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate; Transfection | 2006 |
Selective inhibition of spontaneous but not Ca2+ -dependent release machinery by presynaptic group II mGluRs in rat cerebellar slices.
Topics: Action Potentials; Animals; Cadmium; Calcium; Calcium Channels; Cerebellum; Colforsin; Cyclopropanes; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Interneurons; N-Methylaspartate; Nickel; Patch-Clamp Techniques; Presynaptic Terminals; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Vesicles | 2006 |
Kainate receptor-mediated inhibition of glutamate release involves protein kinase A in the mouse hippocampus.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Excitatory Postsynaptic Potentials; Glutamic Acid; GTP-Binding Proteins; Hippocampus; Kainic Acid; Mice; Mice, Inbred C57BL; Mossy Fibers, Hippocampal; Pyramidal Cells; Receptors, Kainic Acid; Second Messenger Systems; Signal Transduction | 2006 |
Mitochondrial transport in processes of cortical neurons is independent of intracellular calcium.
Topics: Aldehydes; Animals; Bicuculline; Biological Transport; Calcium; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Colforsin; Female; GABA Antagonists; Glutamic Acid; Image Processing, Computer-Assisted; Mitochondria; Neurons; Pregnancy; Rats; Rats, Sprague-Dawley | 2006 |
Differential regulation of two distinct voltage-dependent sodium currents by group III metabotropic glutamate receptor activation in insect pacemaker neurons.
Topics: Algorithms; Animals; Biological Clocks; Calcium Channel Blockers; Cell Separation; Colforsin; Cyclic AMP; Electrophysiology; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Ion Channel Gating; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Periplaneta; Pertussis Toxin; Potassium Channel Blockers; Receptors, Metabotropic Glutamate; Signal Transduction; Sodium Channels | 2006 |
Neurosteroid pregnenolone sulfate enhances glutamatergic synaptic transmission by facilitating presynaptic calcium currents at the calyx of Held of immature rats.
Topics: Animals; Animals, Newborn; Brain Stem; Calcium; Calcium Channels; Cell Line; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamic Acid; Humans; In Vitro Techniques; Membrane Potentials; Patch-Clamp Techniques; Phorbol Esters; Pregnenolone; Presynaptic Terminals; Rabbits; Rats; Rats, Wistar; Synaptic Transmission; Time Factors; Transfection | 2006 |
D1-like dopamine receptors selectively block P/Q-type calcium channels to reduce glutamate release onto cholinergic basal forebrain neurones of immature rats.
Topics: Animals; Benzazepines; Calcium Channel Blockers; Calcium Channels, P-Type; Calcium Channels, Q-Type; Choline O-Acetyltransferase; Colforsin; Data Interpretation, Statistical; Dopamine Agonists; Dopamine Antagonists; Electrophysiology; Excitatory Postsynaptic Potentials; Fluorescent Antibody Technique; Fluorescent Dyes; Glutamic Acid; Injections, Intraventricular; Parasympathetic Nervous System; Patch-Clamp Techniques; Prosencephalon; Rats; Receptor, Nerve Growth Factor; Receptors, Dopamine D1 | 2007 |
Upregulation of the glutamine transporter through transactivation mediated by cAMP/protein kinase A signals toward exacerbation of vulnerability to oxidative stress in rat neocortical astrocytes.
Topics: Adenylyl Cyclases; Amino Acid Transport System A; Animals; Astrocytes; Carrier Proteins; Cell Survival; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Hydrogen Peroxide; Isoquinolines; Mutation; Neocortex; Neurons; Oxidative Stress; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Sulfonamides; Time Factors; Transcription Factor AP-1; Transfection; Up-Regulation | 2007 |
Bidirectional synaptic plasticity at nociceptive afferents in the rat central amygdala.
Topics: Adenylyl Cyclases; Amygdala; Animals; Calcium Signaling; Colforsin; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Isoquinolines; Long-Term Potentiation; Long-Term Synaptic Depression; Neuronal Plasticity; Neurons, Afferent; Nociceptors; Okadaic Acid; Pain; Phosphoprotein Phosphatases; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Synaptic Transmission | 2007 |
Serotonergic modulation of GABAergic and glutamatergic synaptic transmission in mechanically isolated rat medial preoptic area neurons.
Topics: Animals; Colforsin; Evoked Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Neurons; Patch-Clamp Techniques; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Synaptic Transmission | 2008 |
Changes in the spontaneous calcium oscillations for the development of the preconditioning-induced ischemic tolerance in neuron/astrocyte co-culture.
Topics: Animals; Astrocytes; Blotting, Western; Brain Ischemia; Calcium; Calcium Signaling; Cell Survival; Coculture Techniques; Colforsin; Down-Regulation; Excitatory Amino Acid Transporter 2; Glucose; Glutamic Acid; Ischemic Preconditioning; Neurons; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats | 2007 |
Involvement of hyperpolarization-activated cation channels in synaptic modulation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Neural Pathways; Neurons; Phosphodiesterase Inhibitors; Potassium; Potassium Channel Blockers; Potassium Channels; Presynaptic Terminals; Pyrimidines; Rats; Rats, Wistar; Synaptic Membranes; Synaptic Transmission | 2007 |
Regulatory role of C-terminus in the G-protein coupling of the metabotropic glutamate receptor 1.
Topics: Amino Acid Sequence; Animals; Calcium; Cell Line, Transformed; Chromones; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; GTP-Binding Proteins; Humans; Membrane Potentials; Models, Molecular; Mutation; Patch-Clamp Techniques; Pertussis Toxin; Potassium Chloride; Protein Structure, Tertiary; Rats; Receptors, Metabotropic Glutamate; Signal Transduction; Transfection | 2008 |
Partial compensation for N-type Ca(2+) channel loss by P/Q-type Ca(2+) channels underlines the differential release properties supported by these channels at cerebrocortical nerve terminals.
Topics: 4-Aminopyridine; Aminobutyrates; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cerebral Cortex; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Exocytosis; Gene Knockout Techniques; Glutamic Acid; Mice; Oligonucleotides, Antisense; Phorbol Esters; Potassium Channel Blockers; Presynaptic Terminals; Receptors, Metabotropic Glutamate; Synaptosomes | 2009 |
Critical involvement of postsynaptic protein kinase activation in long-term potentiation at hippocampal mossy fiber synapses on CA3 interneurons.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Benzophenanthridines; CA3 Region, Hippocampal; Catalytic Domain; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Interneurons; Intracellular Signaling Peptides and Proteins; Long-Term Potentiation; Male; Mossy Fibers, Hippocampal; Organ Culture Techniques; Peptide Fragments; Phorbol Esters; Phosphodiesterase Inhibitors; Protein Kinase C; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Signal Transduction; Synaptic Membranes; Synaptic Transmission | 2010 |
ATP and noradrenaline activate CREB in astrocytes via noncanonical Ca(2+) and cyclic AMP independent pathways.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Glutamic Acid; HEK293 Cells; Humans; Norepinephrine; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Transcription, Genetic | 2012 |
Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biophysics; Biotinylation; Cells, Cultured; Colforsin; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Postsynaptic Potentials; Flow Cytometry; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Indoles; Kainic Acid; Long-Term Potentiation; Male; Neurons; Protein Transport; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Valine | 2012 |
CCL5-glutamate interaction in central nervous system: Early and acute presynaptic defects in EAE mice.
Topics: Age Factors; Animals; Animals, Newborn; Central Nervous System; Chemokine CCL5; Colforsin; D-Aspartic Acid; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Exocytosis; Female; Glutamic Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Potassium Chloride; Second Messenger Systems; Synaptosomes; Time Factors; Tritium | 2013 |
β-Adrenergic receptors activate exchange protein directly activated by cAMP (Epac), translocate Munc13-1, and enhance the Rab3A-RIM1α interaction to potentiate glutamate release at cerebrocortical nerve terminals.
Topics: Adjuvants, Immunologic; Adrenergic beta-Agonists; Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Enzyme Inhibitors; Glutamic Acid; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Isoproterenol; Mice; Naphthalenes; Nerve Tissue Proteins; Presynaptic Terminals; Protein Transport; rab3A GTP-Binding Protein; Receptors, Adrenergic, beta; Synaptic Membranes; Synaptic Transmission; Type C Phospholipases | 2013 |
A real-time method for measuring cAMP production modulated by Gαi/o-coupled metabotropic glutamate receptors.
Topics: Amino Acids; Animals; Biosensing Techniques; Buffers; Cell Culture Techniques; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gi-Go; Luciferases, Firefly; Radioligand Assay; Receptors, Metabotropic Glutamate; Reproducibility of Results; Sensitivity and Specificity; Transfection; Xanthenes | 2014 |
Methamphetamine and HIV-1-induced neurotoxicity: role of trace amine associated receptor 1 cAMP signaling in astrocytes.
Topics: Astrocytes; Cells, Cultured; Central Nervous System Agents; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 2; Gene Knockdown Techniques; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; HIV Infections; HIV-1; Humans; Methamphetamine; Phenethylamines; Receptors, G-Protein-Coupled; RNA Interference; RNA, Messenger | 2014 |
A mechanistic study on urine retention in d-amphetamine addicts.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Amidines; Amphetamine-Related Disorders; Animals; Benzophenanthridines; Central Nervous System Stimulants; Chronic Disease; Colforsin; Dextroamphetamine; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Isoquinolines; N-Methylaspartate; Oxidants; Protein Kinase Inhibitors; Rats, Wistar; Reflex; Spinal Cord; Sulfonamides; Urinary Retention; Urination; Valine | 2014 |
Neuroprotective role of prostaglandin PGE2 EP2 receptor in hemin-mediated toxicity.
Topics: Adjuvants, Immunologic; Alprostadil; Analysis of Variance; Animals; Animals, Newborn; Cell Survival; Cerebral Cortex; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Hemin; L-Lactate Dehydrogenase; Mice; Mice, Knockout; Neurons; Neuroprotective Agents; Receptors, Prostaglandin E, EP2 Subtype; Thionucleotides | 2015 |
Presynaptic G Protein-Coupled Receptors Differentially Modulate Spontaneous Glutamate Release in the Supraoptic Nucleus.
Topics: Adenosine A1 Receptor Agonists; Animals; Colforsin; Excitatory Amino Acid Agonists; GABA-B Receptor Agonists; Glutamic Acid; Male; Miniature Postsynaptic Potentials; Nifedipine; Norepinephrine; Presynaptic Terminals; Rats; Receptors, G-Protein-Coupled; Supraoptic Nucleus | 2016 |
Recruitment of release sites underlies chemical presynaptic potentiation at hippocampal mossy fiber boutons.
Topics: Animals; Colforsin; Glutamic Acid; Male; Mice, Inbred C57BL; Microscopy, Fluorescence, Multiphoton; Mossy Fibers, Hippocampal; Neurotransmitter Agents; Presynaptic Terminals; Synaptic Vesicles | 2021 |
The upregulation of glutamate decarboxylase 67 against hippocampal excitability damage in male fetal rats by prenatal caffeine exposure.
Topics: Adenylyl Cyclases; Animals; Brain-Derived Neurotrophic Factor; Caffeine; Colforsin; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Hippocampus; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptor, Adenosine A2A; Up-Regulation | 2022 |