Page last updated: 2024-08-23

colforsin and genistein

colforsin has been researched along with genistein in 98 studies

Research

Studies (98)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	42 (42.86)	18.2507
2000's	43 (43.88)	29.6817
2010's	13 (13.27)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Balch, WE; Frizzell, RA; Gentzsch, M; Gottesfeld, JM; Herman, D; Hoch, B; Hutt, DM; Kellner, W; Kelly, JW; Lukacs, GL; Manning, G; Matsumura, Y; Matteson, J; Noel, S; Okiyoneda, T; Pilewski, JM; Riordan, JR; Rodrigues, AP; Schmidt, A; Skach, WR; Sorscher, EJ; Thomas, PJ; Yates, JR	1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P	1
Fernandez-Gallardo, S; Guntaka, RV; Kandala, JC; Lim, RW; Shukla, SD; Tripathi, YB	1
Billig, H; Hsueh, AJ; Kowalski, KI; Tilly, JL	1
Kang, JJ; Kuo, ML; Yang, NC	1
Hall, A; Ridley, AJ	1
Fischer, H; Illek, B; Machen, TE; Reenstra, WW; Santos, GF; Widdicombe, JH	1
Chik, CL; Ho, AK; Murdoch, G; Ogiwara, T; Wiest, R	1
Boyer, B; Thiery, JP	1
Joshi-Barve, SS; Rangnekar, VM; Rangnekar, VV; Sells, SF	1
Good, DW	1
Braverman, LE; Devito, WJ; Mori, K; Stone, S	1
Dam, A; Raman, S; Reenstra, WW; Shorten, S; Yurko-Mauro, K	1
Ogihara, M	1
Asai, T; McDonald, TF; Pelzer, S; Shuba, LM	1
Diener, M; Hug, F	1
Baudet, C; Brachet, P; Canova, C; Chassevent, A; Chevalier, G; Filmon, R; Larra, F; Wion, D	1
Griffon, N; Pilon, C; Sautel, F; Schwartz, JC; Sokoloff, P	1
Cheng, TH; Hwang, TC; Price, EM; Wang, F; Yang, IC	1
Illek, B; Machen, TE; Yankaskas, JR	1
Chang, MS; Chen, SA; Chiang, CE; Lin, CI; Luk, HN	1
Hwang, TC; Reenstra, WW; Wang, F; Yang, IC	1
Alper, SL; Izumo, S; Lee, IW; Malek, AM	1
McDonald, TF; Shuba, LM	2
Kumar, CK; Ortiz, A; Said, HM; Yanagawa, N	1
Aller, SG; Forrest, JN; Lehrich, RW; Marino, CR; Webster, P	1
Barritt, GJ; Fernando, KC; Gregory, RB	1
Ma, TY; McCloud, E; Ortiz, A; Said, HM	1
Guo, Y; He, Z; Raman, S; Reenstra, WW	1
Chang, K; Gonda, K; Okamoto, H; Okazaki, H; Shigematsu, H; Takuwa, N; Takuwa, Y; Yatomi, Y	1
El-Mowafy, AM; White, RE	1
Fischer, H; Illek, B	1
Berg, G; Grenegård, M; Nilsson, UK; Svensson, SP	1
Hazama, A; Okada, Y; Zhou, SS	1
Glushakov, AV; Glushakova, HY; Skok, VI	1
Horie, M; Obayashi, K; Sasayama, S; Washizuka, T	1
Hinoue, T; Kidd, M; Läuffer, JM; Modlin, IM; Schmid, SW; Tang, LH; Zhang, T	1
Diener, M; Heinke, B; Hörger, S	1
Ai, W; Gong, J; Yu, L	1
Satake, N; Shibata, S	1
Becker, C; Bouron, A; Porzig, H	1
Frömter, E; Kottra, G; Vank, C	1
Bailey, JL; Fortier, MA; Guilbault, LA; Legault, S; Rouillier, P	1
Lacey, M; Whitehead, SA	1
Hu, S; Hwang, TC; Wang, F; Zeltwanger, S	1
Brandis, M; Greger, R; Hübner, M; Kuehr, J; Kunzelmann, K; Mall, M; Seydewitz, HH; Wissner, A	1
Karlsson, AM; Lerner, MR; Lundström, I; Svensson, SP; Unett, D	1
Delamere, NA; Okafor, MC	1
Nogowski, L; Szkudelska, K; Szkudelski, T	1
Chen, L; Harris, DC; Kairaitis, LK; Wang, Y; Zhang, BH	1
Carew, TJ; Purcell, AL	1
Lacey, M; Nejaty, H; Whitehead, SA	1
Al-Nakkash, L; Reinach, PS	1
Låg, M; Refsnes, M; Schwarze, PE; Thoresen, GH; Thrane, EV	1
Galietta, LV; Jayaraman, S; Verkman, AS	1
George, T; Good, DW	1
Jiang, Q; Kleyman, TR; Li, J; Rubenstein, RC; Suaud, L	1
Ferreira, AT; Neira, I; Yoshida, N	1
Bonanno, JA; Sun, XC	1
DeCarvalho, AC; Gansheroff, LJ; Teem, JL	1
Okada, Y; Takai, A; Zhou, S-	1
Becq, F; Bulteau-Pignoux, L; Derand, R	1
Becq, F; Bulteau-Pignoux, L; Dérand, R; Joffre, M; Métayé, T	1
Mann, GE; Morgan, AJ; Pearson, JD; Sobrevia, L; Steinert, JR; Sugden, D; Wheeler-Jones, CP; Wyatt, AW	1
Burvall, KM; Larsson, K; Palmberg, L	1
Lee, JH; Marcus, DC	1
Du, K; Folli, C; Galietta, LJ; Gopinath, VS; Guy, RK; Lukacs, GL; Ma, T; Pedemonte, N; Shelat, AA; Taddei, A; Verkman, AS; Yang, H	1
Ajonuma, LC; Chan, HC; Chan, LN; Chung, YW; Ho, LS; Lam, SY; Liu, Y; Lo, PS; Shi, QX; Tsang, LL; Wang, XF; Yu, MK; Yuan, YY; Zhao, WC; Zhou, CX	1
Findlay, IA; Li, H; Sheppard, DN	1
Barrett, KE; Childs, D; Chow, JY; Dong, H; Hogan, DL; Isenberg, JI; Pratha, VS; Sellers, ZM; Smith, AJ	1
Becq, F; Norez, C; Robert, R	1
Jain, R; Kansara, V; Mitra, AK; Pal, D	1
Caci, E; Du, K; Galietta, LJ; Lukacs, GL; Pedemonte, N; Verkman, AS; Zegarra-Moran, O	1
Bebok, Z; Clancy, JP; Collawn, JF; Li, Y; Parker, W; Sorscher, EJ; Varga, K; Wakefield, J	1
Baines, DL; Woollhead, AM	1
Kerem, E	1
Rubenstein, RC; Suaud, L; Yan, W	1
Al-Nakkash, L; Chen, YJ; Clarke, LL; Cooper, K; Rottinghaus, GE; Rubin, LJ	1
Capron, B; Godaux, E; Ris, L; Sindic, C; Wattiez, R	1
Becq, F; Guibert, C; Norez, C; Robert, R; Savineau, JP	1
Bijvelds, MJ; de Jonge, HR; Houtsmuller, AB; Lim, CH; Nigg, A; Schoonderwoerd, K; Tilly, BC	1
Choy, PC; Keung, W; Leung, GP; Man, RY; Ng, KF; Ng, WW; Vanhoutte, PM; Xu, YC	1
Al-Nakkash, L; Kurth, MJ; Nantz, MH; Springsteel, MF	1
Akingbemi, BT; Braden, TD; Coleman, ES; Hancock, KD; Kemppainen, BW; Morrison, EE; Tao, YX	1
Seidler, U; Tuo, B; Wen, G	1
Clancy, JP; Collawn, J; Fan, L; Fortenberry, J; Fulton, J; Jurkevante, A; Li, Y; Mazur, M; Pyle, LC; Rowe, SM; Sloane, PA; Sorscher, EJ; Varga, K; Woodworth, B	1
Bompadre, SG; Hwang, TC; Li, M; Miki, H; Zhou, Z	1
Kongsuphol, P; Kraidith, K; Kunzelmann, K; Schreiber, R	1
Al-Nakkash, L; Batia, L; Bhakta, M; Hale, N; Jensen, J; Peterson, A; Sears, S; Skinner, R	1
Becq, F; Gimenez-Maitre, A; Guillaume, C; Jacquot, J; Laurent-Maquin, D; Le Henaff, C; Norez, C; Ravoninjatovo, B	1
Campochiaro, PA; Gong, YY; Hackett, SF; Iwase, T; Lu, L; Seidel, CP; Stevens, RK; Wang, X	1
Al-Nakkash, L	1
Beekman, JM; van der Ent, CK; Vijftigschild, LA	1
Deachapunya, C; Poonyachoti, S	1
Cao, HH; Fang, F; Jiang, Y; Luan, J; Yang, H; Yu, B	1
Bijvelds, MJC; Bose, SJ; Bot, AGM; Cai, Z; de Jonge, HR; Liu, J; Sheppard, DN; Wang, Y	1

Reviews

1 review(s) available for colforsin and genistein

Article	Year
Mutation specific therapy in CF. Paediatric respiratory reviews, 2006, Volume: 7 Suppl 1 Topics: Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA; Enzyme Inhibitors; Genistein; Gentamicins; Humans; Mutation; Treatment Outcome	2006

Other Studies

97 other study(ies) available for colforsin and genistein

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis. Nature chemical biology, 2010, Volume: 6, Issue:1 Topics: Animals; Bronchi; Cell Membrane; Cricetinae; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Gene Silencing; Histone Deacetylases; Humans; Hydroxamic Acids; Mutation; Protein Denaturation; Protein Folding; RNA, Small Interfering; Vorinostat	2010
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22 Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship	2012
Involvement of tyrosine kinase and protein kinase C in platelet-activating-factor-induced c-fos gene expression in A-431 cells. The Biochemical journal, 1992, Sep-01, Volume: 286 ( Pt 2) Topics: Alkaloids; Blotting, Northern; Cinnamates; Colforsin; Cycloheximide; Gene Expression; Genes, fos; Genistein; Humans; Isoflavones; Platelet Activating Factor; Protein Kinase C; Protein-Tyrosine Kinases; RNA; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured	1992
Epidermal growth factor and basic fibroblast growth factor suppress the spontaneous onset of apoptosis in cultured rat ovarian granulosa cells and follicles by a tyrosine kinase-dependent mechanism. Molecular endocrinology (Baltimore, Md.), 1992, Volume: 6, Issue:11 Topics: Animals; Apoptosis; Cells, Cultured; Colforsin; Enzyme Activation; Epidermal Growth Factor; Female; Fibroblast Growth Factor 2; Genistein; Granulosa Cells; Isoflavones; Ovarian Follicle; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Transforming Growth Factor alpha	1992
Effects of signalling transduction modulators on the transformed phenotypes in v-H-ras-transformed NIH 3T3 cells. Cancer letters, 1993, Nov-01, Volume: 74, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; Catechols; Colforsin; Genes, ras; Genistein; Isoflavones; Mice; Nitriles; Phenotype; Signal Transduction; Tyrphostins	1993
Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase. The EMBO journal, 1994, Jun-01, Volume: 13, Issue:11 Topics: 3T3 Cells; Actins; Animals; Bombesin; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Genistein; GTP Phosphohydrolases; GTP-Binding Proteins; Isoflavones; Lysophospholipids; Mice; Models, Biological; Myosins; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Protein-Tyrosine Kinases; rhoA GTP-Binding Protein; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella	1994
cAMP-independent activation of CFTR Cl channels by the tyrosine kinase inhibitor genistein. The American journal of physiology, 1995, Volume: 268, Issue:4 Pt 1 Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; Calcium; Chloride Channels; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Electrophysiology; Genistein; Intracellular Membranes; Isoflavones; Membrane Proteins; Mice; Protein-Tyrosine Kinases; Vanadates	1995
Potentiation of agonist-stimulated cyclic AMP accumulation by tyrosine kinase inhibitors in rat pinealocytes. Journal of neurochemistry, 1995, Volume: 65, Issue:4 Topics: Animals; Cholera Toxin; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Activation; Genistein; Isoflavones; Isoproterenol; Male; Norepinephrine; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Pineal Gland; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley	1995
Cyclic AMP distinguishes between two functions of acidic FGF in a rat bladder carcinoma cell line. The Journal of cell biology, 1993, Volume: 120, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Benzylidene Compounds; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; DNA Replication; Fibroblast Growth Factor 1; Genistein; Isoflavones; Kinetics; Nitriles; Protein-Tyrosine Kinases; Rats; Signal Transduction; Transforming Growth Factor beta; Tumor Cells, Cultured; Tyrphostins; Urinary Bladder Neoplasms; Vanadates; Virulence Factors, Bordetella	1993
Interleukin-1-inducible expression of gro-beta via NF-kappa B activation is dependent upon tyrosine kinase signaling. The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24 Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Cell Line; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Colforsin; Cytomegalovirus; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, jun; Genes, myc; Genistein; Growth Substances; HeLa Cells; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-1; Isoflavones; L Cells; Melanoma; Mice; Molecular Sequence Data; NF-kappa B; Oligonucleotide Probes; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection; Tumor Cells, Cultured	1993
Hyperosmolality inhibits bicarbonate absorption in rat medullary thick ascending limb via a protein-tyrosine kinase-dependent pathway. The Journal of biological chemistry, 1995, Apr-28, Volume: 270, Issue:17 Topics: Absorption; Alkaloids; Animals; Arginine Vasopressin; Benzoquinones; Bicarbonates; Colforsin; Dinoprostone; Drug Interactions; Genistein; Isoflavones; Kidney Medulla; Lactams, Macrocyclic; Loop of Henle; Mannitol; Molybdenum; Osmolar Concentration; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Sodium Chloride; Staurosporine	1995
Involvement of tyrosine phosphorylation in the regulation of 5'-deiodinases in FRTL-5 rat thyroid cells and rat astrocytes. Endocrinology, 1996, Volume: 137, Issue:4 Topics: Animals; Astrocytes; Bucladesine; Cell Line; Colforsin; Drug Combinations; Enzyme Inhibitors; Gene Expression; Genistein; Hydrocortisone; Iodide Peroxidase; Isoenzymes; Isoflavones; Phosphorylation; Rats; RNA, Messenger; Thyroid Gland; Thyrotropin; Tyrosine	1996
CFTR chloride channel activation by genistein: the role of serine/threonine protein phosphatases. The American journal of physiology, 1996, Volume: 271, Issue:2 Pt 1 Topics: 3T3 Cells; Animals; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Synergism; Genistein; Isoflavones; Isoquinolines; Marine Toxins; Mice; Oxazoles; Phosphoprotein Phosphatases; Protein Kinase Inhibitors; Sulfonamides; Transfection	1996
Cell-density-dependent expression of the alpha(2)-adrenergic response by epidermal growth factor (EGF) in primary cultures of adult rat hepatocytes. Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cell Count; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Cytochalasin B; Epidermal Growth Factor; Genistein; Isoflavones; Liver; Male; Oxymetazoline; Pertussis Toxin; Protein Biosynthesis; Proteins; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella; Yohimbine	1996
Activation of cardiac chloride conductance by the tyrosine kinase inhibitor, genistein. British journal of pharmacology, 1996, Volume: 119, Issue:2 Topics: Animals; Chloride Channels; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Genistein; Guinea Pigs; Heart; Heart Ventricles; Isoflavones; Membrane Potentials; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Vanadates; Ventricular Function	1996
Modulation of Cl- secretion in rat distal colon by genistein, a protein tyrosine kinase inhibitor. European journal of pharmacology, 1996, Mar-28, Volume: 299, Issue:1-3 Topics: Animals; Carbachol; Chlorides; Colforsin; Colon; Enzyme Inhibitors; Female; Genistein; In Vitro Techniques; Isoflavones; Patch-Clamp Techniques; Protein-Tyrosine Kinases; Rats	1996
1,25-Dihydroxyvitamin D3 induces programmed cell death in a rat glioma cell line. Journal of neuroscience research, 1996, Dec-01, Volume: 46, Issue:5 Topics: Animals; Apoptosis; Calcitriol; Colforsin; Cycloheximide; DNA-Binding Proteins; Endothelial Growth Factors; GADD45 Proteins; Genistein; Glioma; Interleukin-6; Intracellular Signaling Peptides and Proteins; Isoflavones; Lymphokines; Nerve Tissue Proteins; Nuclear Receptor Subfamily 4, Group A, Member 1; Protein Biosynthesis; Proteins; Proto-Oncogene Proteins c-myc; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	1996
Two intracellular signaling pathways for the dopamine D3 receptor: opposite and synergistic interactions with cyclic AMP. Journal of neurochemistry, 1997, Volume: 68, Issue:1 Topics: Cell Line; Colforsin; Cyclic AMP; Dopamine Agonists; Enzyme Inhibitors; Genistein; Humans; Intracellular Membranes; Isoflavones; Mitosis; Protein-Tyrosine Kinases; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D3; Signal Transduction; Time Factors	1997
Modulation of CFTR chloride channels by calyculin A and genistein. The American journal of physiology, 1997, Volume: 272, Issue:1 Pt 1 Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Cell Line; Chloride Channels; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Synergism; Enzyme Inhibitors; Genistein; Hydrolysis; Insecta; Ion Channel Gating; Isoflavones; Marine Toxins; Mice; Oxazoles; Phosphoprotein Phosphatases; Protein-Tyrosine Kinases	1997
cAMP and genistein stimulate HCO3- conductance through CFTR in human airway epithelia. The American journal of physiology, 1997, Volume: 272, Issue:4 Pt 1 Topics: Adenosine Triphosphate; Bicarbonates; Cell Membrane; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Enzyme Inhibitors; Genistein; Glyburide; Humans; Isoflavones; Lung; ortho-Aminobenzoates; Phosphoric Monoester Hydrolases; Tumor Cells, Cultured	1997
Genistein directly induces cardiac CFTR chloride current by a tyrosine kinase-independent and protein kinase A-independent pathway in guinea pig ventricular myocytes. Biochemical and biophysical research communications, 1997, Jun-09, Volume: 235, Issue:1 Topics: Adrenergic beta-Agonists; Animals; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Female; Genistein; Guinea Pigs; Heart Ventricles; Isoflavones; Isoproterenol; Isoquinolines; Male; Marine Toxins; Myocardium; Oxazoles; Patch-Clamp Techniques; Protein-Tyrosine Kinases; Sulfonamides	1997
Genistein potentiates wild-type and delta F508-CFTR channel activity. The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 1 Topics: 3T3 Cells; Adenosine Triphosphate; Analysis of Variance; Animals; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; DNA, Complementary; Genistein; Growth Inhibitors; Humans; Iodides; Isoflavones; Kinetics; Membrane Potentials; Mice; Point Mutation; Recombinant Proteins; Transfection	1997
Regulation of endothelin-1 gene expression by cell shape and the microfilament network in vascular endothelium. The American journal of physiology, 1997, Volume: 273, Issue:5 Topics: Actin Cytoskeleton; Actins; Animals; Aorta; Cattle; Cell Size; Cells, Cultured; Colforsin; Cytochalasin D; Cytoskeleton; Endothelin-1; Endothelium, Vascular; Gene Expression Regulation; Genistein; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic	1997
Synergistic activation of guinea-pig cardiac cystic fibrosis transmembrane conductance regulator by the tyrosine kinase inhibitor genistein and cAMP. The Journal of physiology, 1997, Nov-15, Volume: 505 ( Pt 1) Topics: Acetylcholine; Adenylyl Cyclases; Animals; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Genistein; Guinea Pigs; Isoquinolines; Myocardium; Patch-Clamp Techniques; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Sulfonamides; Vanadates	1997
Mechanism and regulation of riboflavin uptake by human renal proximal tubule epithelial cell line HK-2. The American journal of physiology, 1998, Volume: 274, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Biological Transport; Bucladesine; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; Genistein; Humans; Isoquinolines; Kidney Tubules, Proximal; Kinetics; Nitriles; Protein Kinase C; Protein-Tyrosine Kinases; Riboflavin; Sulfonamides; Temperature; Tyrphostins	1998
Vasoactive intestinal peptide, forskolin, and genistein increase apical CFTR trafficking in the rectal gland of the spiny dogfish, Squalus acanthias. Acute regulation of CFTR trafficking in an intact epithelium. The Journal of clinical investigation, 1998, Feb-15, Volume: 101, Issue:4 Topics: Animals; Antibodies; Antimetabolites; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Dogfish; Female; Genistein; Humans; Male; Microscopy, Fluorescence; Perfusion; Salt Gland; Vasoactive Intestinal Peptide; Xenopus laevis	1998
Protein kinase A regulates the disposition of Ca2+ which enters the cytoplasmic space through store-activated Ca2+ channels in rat hepatocytes by diverting inflowing Ca2+ to mitochondria. The Biochemical journal, 1998, Mar-15, Volume: 330 ( Pt 3) Topics: Adenosine Triphosphate; Aluminum Compounds; Animals; Bucladesine; Calcium; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Enzyme Inhibitors; Fluorides; Genistein; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Liver; Mitochondria, Liver; Rats; Thapsigargin; Vasopressins	1998
Riboflavin uptake by the human-derived liver cells Hep G2: mechanism and regulation. Journal of cellular physiology, 1998, Volume: 176, Issue:3 Topics: Antiemetics; Biological Transport; Bucladesine; Calcium; Calmodulin; Carcinogens; Carcinoma, Hepatocellular; Carrier Proteins; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Flavins; Genistein; Humans; Imidazoles; Protein Kinase C; Riboflavin; Signal Transduction; Tetradecanoylphorbol Acetate; Trifluoperazine; Tritium; Tumor Cells, Cultured; Vanadates	1998
Cystic fibrosis transmembrane conductance regulator activation by cAMP-independent mechanisms. The American journal of physiology, 1998, Volume: 275, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; Benzimidazoles; Chlorophenols; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Genistein; Humans; Kinetics; Marine Toxins; Mice; Oxazoles; Phosphopeptides; Phosphorylation; Recombinant Proteins; Sequence Deletion; Transfection; Xanthines	1998
EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition. The Journal of biological chemistry, 1998, Oct-16, Volume: 273, Issue:42 Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Colforsin; Cricetinae; Enzyme Activation; Genistein; GTP-Binding Protein alpha Subunits, Gi-Go; Immediate-Early Proteins; Lysophospholipids; Pertussis Toxin; ras Proteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; Signal Transduction; Sphingosine; Type C Phospholipases; Virulence Factors, Bordetella	1998
Evidence for a tyrosine kinase-dependent activation of the adenylyl Cyclase/PKA cascade downstream from the G-protein-linked endothelin ETA receptor in vascular smooth muscle. Biochemical and biophysical research communications, 1998, Oct-20, Volume: 251, Issue:2 Topics: Adenylyl Cyclases; Animals; Benzoquinones; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; In Vitro Techniques; Kinetics; Lactams, Macrocyclic; Muscle, Smooth, Vascular; Peptides; Protein-Tyrosine Kinases; Quinones; Receptor, Endothelin A; Receptors, Endothelin; Rifabutin; Signal Transduction; Swine; Vanadates; Viper Venoms	1998
Flavonoids stimulate Cl conductance of human airway epithelium in vitro and in vivo. The American journal of physiology, 1998, Volume: 275, Issue:5 Topics: Cell Line; Chamomile; Chloride Channels; Chlorides; Colforsin; Epithelial Cells; Flavonoids; Genistein; Humans; Kaempferols; Kinetics; Lung; Membrane Potentials; Models, Biological; Oils, Volatile; Patch-Clamp Techniques; Plants, Medicinal; Quercetin; Structure-Activity Relationship	1998
Different proliferative responses of Gi/o-protein-coupled receptors in human myometrial smooth muscle cells. A possible role of calcium. Journal of molecular neuroscience : MN, 1998, Volume: 11, Issue:1 Topics: Adrenergic Agents; Binding, Competitive; Calcium; Cell Division; Cell Size; Cells, Cultured; Colforsin; DNA; Female; Genistein; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Lysophospholipids; Myometrium; Norepinephrine; Phosphorylation; Phosphotyrosine; Pregnancy; Receptors, Adrenergic, alpha; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid	1998
Tyrosine kinase-independent extracellular action of genistein on the CFTR Cl- channel in guinea pig ventricular myocytes and CFTR-transfected mouse fibroblasts. The Japanese journal of physiology, 1998, Volume: 48, Issue:5 Topics: 3T3 Cells; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Extracellular Space; Genistein; Guinea Pigs; In Vitro Techniques; Mice; Myocardium; Patch-Clamp Techniques; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Transfection	1998
Modulation of nicotinic acetylcholine receptor activity in submucous neurons by intracellular messengers. Journal of the autonomic nervous system, 1999, Jan-15, Volume: 75, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Colforsin; Enzyme Inhibitors; Genistein; Guinea Pigs; In Vitro Techniques; Intestinal Mucosa; Neurons; Parasympatholytics; Phorbol Esters; Receptors, Nicotinic; Second Messenger Systems; Thapsigargin	1999
Genistein inhibits slow component delayed-rectifier K currents via a tyrosine kinase-independent pathway. Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:12 Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophysiology; Genistein; Heart; In Vitro Techniques; Ion Exchange; Isoflavones; Isoproterenol; Membrane Potentials; Myocardium; Patch-Clamp Techniques; Phenols; Phosphoric Diester Hydrolases; Potassium Channels; Protein-Tyrosine Kinases; Swine; Time Factors; Tyrphostins; Vanadates	1998
Pituitary adenylate cyclase-activating polypeptide modulates gastric enterochromaffin-like cell proliferation in rats. Gastroenterology, 1999, Volume: 116, Issue:3 Topics: Androstadienes; Animals; Cell Division; Cells, Cultured; Colforsin; DNA; Enterochromaffin Cells; Female; Flavonoids; Gastric Mucosa; Gastrins; Genistein; Humans; Neuropeptides; Neurotransmitter Agents; Octreotide; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone; Receptors, Vasoactive Intestinal Peptide; Signal Transduction; Terfenadine; Vasoactive Intestinal Peptide; Wortmannin	1999
The protein tyrosine kinase pathway is not involved in the regulation of K+ transport across the rat colon. Acta physiologica Scandinavica, 1999, Volume: 165, Issue:4 Topics: Animals; Colforsin; Colon; Enzyme Inhibitors; Genistein; In Vitro Techniques; Indomethacin; Ion Transport; Mucous Membrane; Potassium; Potassium Channels; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Rubidium Radioisotopes	1999
Lack of involvement of G proteins in the activation of cardiac CFTR Cl- current by genistein. Pflugers Archiv : European journal of physiology, 1999, Volume: 437, Issue:6 Topics: Adenylate Cyclase Toxin; Animals; Calcium Channels; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guinea Pigs; Heart; Isoproterenol; Pertussis Toxin; Protein-Tyrosine Kinases; Sympathomimetics; Thionucleotides; Virulence Factors, Bordetella	1999
MAP kinase activation by mu opioid receptor involves phosphatidylinositol 3-kinase but not the cAMP/PKA pathway. FEBS letters, 1999, Jul-30, Volume: 456, Issue:1 Topics: Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Chromones; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Indoles; Maleimides; Morphine; Morpholines; Naloxone; Narcotic Antagonists; Narcotics; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Receptors, Opioid, mu; Recombinant Proteins; Thionucleotides; Transfection; Wortmannin	1999
The potentiating effect of genistein on the relaxation induced by isoproterenol in rat aortic rings. General pharmacology, 1999, Volume: 33, Issue:3 Topics: Adrenergic beta-Agonists; Animals; Aorta; Benzoflavones; Bucladesine; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Genistein; In Vitro Techniques; Isoproterenol; Male; Methoxsalen; Muscle Relaxation; Phosphodiesterase Inhibitors; Quinacrine; Rats; Rats, Wistar; Theophylline	1999
Functional expression of voltage-gated Na+ and Ca2+ channels during neuronal differentiation of PC12 cells with nerve growth factor or forskolin. Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:5 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Barium; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Count; Cell Differentiation; Cell Membrane; Colforsin; Genistein; Ion Channel Gating; Nerve Growth Factors; Neurites; Patch-Clamp Techniques; PC12 Cells; Radioligand Assay; Rats; Sodium; Sodium Channels	1999
The activation of an apical Cl- conductance by extracellular ATP is potentiated by genistein in Necturus gallbladder epithelium. Pflugers Archiv : European journal of physiology, 1999, Volume: 438, Issue:4 Topics: Adenosine Triphosphate; Animals; Cell Membrane; Chlorides; Colforsin; Drug Synergism; Electric Conductivity; Enzyme Inhibitors; Epithelium; Extracellular Space; Gallbladder; Genistein; Necturus maculosus; Protein-Tyrosine Kinases	1999
Intracellular regulation of estradiol and progesterone production by cultured bovine granulosa cells. Molecular reproduction and development, 1999, Volume: 54, Issue:4 Topics: Adenylyl Cyclases; Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Female; Genistein; Granulosa Cells; Progesterone; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Receptors, FSH; Signal Transduction; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha	1999
Protein tyrosine kinase activity of lavendustin A and the phytoestrogen genistein on progesterone synthesis in cultured rat ovarian cells. Fertility and sterility, 2000, Volume: 73, Issue:3 Topics: Animals; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Follicle Stimulating Hormone; Genistein; Interleukin-1; Nitrites; Ovary; Phenols; Progesterone; Protein-Tyrosine Kinases; Rats; Rats, Wistar	2000
Deletion of phenylalanine 508 causes attenuated phosphorylation-dependent activation of CFTR chloride channels. The Journal of physiology, 2000, May-01, Volume: 524 Pt 3 Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Deletion; Genistein; Ion Channel Gating; Mice; Patch-Clamp Techniques; Phenylalanine; Phosphorylation; Point Mutation; Protein Structure, Tertiary; Thionucleotides	2000
Effect of genistein on native epithelial tissue from normal individuals and CF patients and on ion channels expressed in Xenopus oocytes. British journal of pharmacology, 2000, Volume: 130, Issue:8 Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Aged; Amiloride; Animals; Child; Child, Preschool; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Epithelium; Female; Gene Expression; Genistein; Humans; Ion Channels; Ion Transport; Membrane Potentials; Middle Aged; Mutation; Nasal Cavity; Oocytes; Rectum; Sodium Channels; Xenopus	2000
Melatonin-induced organelle movement in melanophores is coupled to tyrosine phosphorylation of a high molecular weight protein. Cellular signalling, 2000, Volume: 12, Issue:7 Topics: Adenylate Cyclase Toxin; Animals; Blotting, Western; Cell Aggregation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Genistein; GTP-Binding Proteins; Kinetics; Melanophores; Melatonin; Pertussis Toxin; Phosphoprotein Phosphatases; Phosphorylation; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serine; Signal Transduction; Threonine; Time Factors; Tyrosine; Virulence Factors, Bordetella; Xenopus	2000
The inhibitory influence of endothelin on active sodium-potassium transport in porcine lens. Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:5 Topics: Animals; Biological Transport, Active; Colforsin; Cyclic AMP; Endothelin-1; Enzyme Inhibitors; Genistein; Lens, Crystalline; Oligopeptides; Potassium; Receptors, Endothelin; Rubidium Radioisotopes; Sodium; Sodium-Potassium-Exchanging ATPase; Swine	2001
Genistein affects lipogenesis and lipolysis in isolated rat adipocytes. The Journal of steroid biochemistry and molecular biology, 2000, Dec-31, Volume: 75, Issue:4-5 Topics: Adipocytes; Animals; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Epinephrine; Estradiol; Estrogens, Non-Steroidal; Genistein; Humans; In Vitro Techniques; Isoflavones; Lipids; Lipolysis; Male; Phytoestrogens; Plant Preparations; Rats; Rats, Wistar; Sterol Esterase	2000
Molecular mechanisms by which iron induces nitric oxide synthesis in cultured proximal tubule cells. Experimental nephrology, 2001, Volume: 9, Issue:3 Topics: Animals; Benzoquinones; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Ferric Compounds; Gene Expression Regulation, Enzymologic; Genistein; Iron; Iron Chelating Agents; Kidney Tubules, Proximal; Lactams, Macrocyclic; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrilotriacetic Acid; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein-Tyrosine Kinases; Pyrrolidines; Quinones; Rats; Rats, Wistar; Rifabutin; RNA, Messenger; Thiocarbamates	2001
Modulation of excitability in Aplysia tail sensory neurons by tyrosine kinases. Journal of neurophysiology, 2001, Volume: 85, Issue:6 Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Action Potentials; Animals; Aplysia; Benzoquinones; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Genistein; Lactams, Macrocyclic; Neuronal Plasticity; Neurons, Afferent; Organometallic Compounds; Phenanthrolines; Phenols; Phosphodiesterase Inhibitors; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; Rifabutin; Serotonin; src-Family Kinases; Tail	2001
Differing effects of endocrine-disrupting chemicals on basal and FSH-stimulated progesterone production in rat granulosa-luteal cells. Experimental biology and medicine (Maywood, N.J.), 2001, Volume: 226, Issue:6 Topics: Animals; Apigenin; Cells, Cultured; Colforsin; Coumarins; DDT; Estradiol; Estrogens; Female; Flavonoids; Follicle Stimulating Hormone; Genistein; Granulosa Cells; Phenols; Progesterone; Rats; Rats, Wistar	2001
Activation of a CFTR-mediated chloride current in a rabbit corneal epithelial cell line. Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:10 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Chlorides; Colforsin; Cornea; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Gene Expression; Genistein; Glyburide; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2001
Mechanisms in fluoride-induced interleukin-8 synthesis in human lung epithelial cells. Toxicology, 2001, Oct-15, Volume: 167, Issue:2 Topics: Androstadienes; Benzylamines; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Epithelial Cells; Flavonoids; Genistein; Humans; Indoles; Interleukin-8; Isoquinolines; Lung; Maleimides; Okadaic Acid; Pertussis Toxin; Protein Kinase C; Signal Transduction; Sodium Fluoride; Sulfonamides; Tetradecanoylphorbol Acetate; Vanadates; Virulence Factors, Bordetella; Wortmannin	2001
Cell-based assay for high-throughput quantitative screening of CFTR chloride transport agonists. American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:5 Topics: Animals; Bacterial Proteins; Benzoquinones; Cell Line; Cells, Cultured; Chloride Channel Agonists; CHO Cells; Colforsin; Cricetinae; Cystic Fibrosis Transmembrane Conductance Regulator; Cytological Techniques; Drug Evaluation, Preclinical; Flavonoids; Genistein; Hydrogen-Ion Concentration; Luminescent Proteins; Microscopy, Fluorescence; Rats; Rats, Inbred F344	2001
Neurotrophin-3 inhibits HCO absorption via a cAMP-dependent pathway in renal thick ascending limb. American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:6 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Absorption; Animals; Arginine Vasopressin; Bicarbonates; Brain-Derived Neurotrophic Factor; Butadienes; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Genistein; Glial Cell Line-Derived Neurotrophic Factor; Loop of Henle; Male; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Nerve Growth Factors; Nerve Tissue Proteins; Neurotrophin 3; Nitriles; Osmolar Concentration; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Rats; Rats, Sprague-Dawley; Renal Agents; Signal Transduction	2001
Genistein restores functional interactions between Delta F508-CFTR and ENaC in Xenopus oocytes. The Journal of biological chemistry, 2002, Mar-15, Volume: 277, Issue:11 Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Sodium Channels; Female; Genistein; Humans; Oocytes; Recombinant Proteins; Sodium Channels; Xenopus laevis	2002
Activation of distinct signal transduction pathways in Trypanosoma cruzi isolates with differential capacity to invade host cells. International journal for parasitology, 2002, Volume: 32, Issue:4 Topics: Animals; Calcium; Calcium Signaling; Chelating Agents; Colforsin; Egtazic Acid; Genistein; HeLa Cells; Host-Parasite Interactions; Humans; Hydrogen-Ion Concentration; Organelles; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; Trypanosoma cruzi	2002
Expression, localization, and functional evaluation of CFTR in bovine corneal endothelial cells. American journal of physiology. Cell physiology, 2002, Volume: 282, Issue:4 Topics: Angiogenesis Inhibitors; Animals; Bicarbonates; Cattle; Cell Membrane Permeability; Cell Polarity; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Endothelium, Corneal; Enzyme Inhibitors; Fluoresceins; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Genistein; Glyburide; Hydrogen-Ion Concentration; Hypoglycemic Agents; Nitrobenzoates; Quinolinium Compounds	2002
Mutations in the nucleotide binding domain 1 signature motif region rescue processing and functional defects of cystic fibrosis transmembrane conductance regulator delta f508. The Journal of biological chemistry, 2002, Sep-27, Volume: 277, Issue:39 Topics: Alleles; Amino Acid Motifs; Amino Acid Sequence; Animals; ATP-Binding Cassette Transporters; Blotting, Western; Cell Line; Chlorine; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Electrophysiology; Gene Deletion; Genetic Vectors; Genistein; HeLa Cells; Humans; Models, Biological; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Plasmids; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Transfection	2002
Regulation of cardiac CFTR Cl(-) channel activity by a Mg(2+)-dependent protein phosphatase. Pflugers Archiv : European journal of physiology, 2002, Volume: 444, Issue:3 Topics: Adenosine Triphosphate; Animals; Anthracenes; Cardiotonic Agents; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Cytosol; Enzyme Inhibitors; Genistein; Guinea Pigs; Isoproterenol; Magnesium; Membrane Potentials; Myocytes, Cardiac; Okadaic Acid; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Protein Phosphatase 2C	2002
The cystic fibrosis mutation G551D alters the non-Michaelis-Menten behavior of the cystic fibrosis transmembrane conductance regulator (CFTR) channel and abolishes the inhibitory Genistein binding site. The Journal of biological chemistry, 2002, Sep-27, Volume: 277, Issue:39 Topics: Animals; Binding Sites; CHO Cells; Colforsin; Cricetinae; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Genistein; Glutathione Transferase; Glycine; Iodides; Kinetics; Models, Chemical; Patch-Clamp Techniques; Protein Binding; Time Factors	2002
Genistein modifies the activation kinetics and magnitude of phosphorylated wild-type and G551D-CFTR chloride currents. The Journal of membrane biology, 2002, Aug-01, Volume: 188, Issue:3 Topics: Adenylyl Cyclases; Animals; Binding Sites; Cell Line; Cells, Cultured; CHO Cells; Colforsin; Cricetinae; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Genistein; Membrane Potentials; Phosphorylation; Reproducibility of Results; Sensitivity and Specificity	2002
Early activation of the p42/p44MAPK pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:12 Topics: Adenosine; Androstadienes; Arginine; Biological Transport; Butadienes; Calcium; Cells, Cultured; Chromones; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Fetus; Flavonoids; Gene Expression; Genistein; Humans; Hydrogen-Ion Concentration; MAP Kinase Signaling System; Membrane Potentials; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitriles; Phenethylamines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Potassium; Protein Isoforms; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Wortmannin	2002
The tyrosine kinase inhibitor genistein increases basal cAMP and potentiates forskolin-induced cAMP accumulation in A549 human airway epithelial cells. Molecular and cellular biochemistry, 2002, Volume: 240, Issue:1-2 Topics: Cell Line; Colforsin; Cyclic AMP; Enzyme Inhibitors; Epithelial Cells; Genistein; Humans; Protein-Tyrosine Kinases	2002
Endolymphatic sodium homeostasis by Reissner's membrane. Neuroscience, 2003, Volume: 119, Issue:1 Topics: Amiloride; Animals; Bumetanide; Cochlear Duct; Colforsin; Diuretics; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Electrodes; Endolymph; Enzyme Inhibitors; Epithelial Cells; Genistein; Gerbillinae; Homeostasis; In Vitro Techniques; Ion Transport; Membrane Potentials; Neuroprotective Agents; Ouabain; Potassium Channel Blockers; Sodium; Vibration	2003
Nanomolar affinity small molecule correctors of defective Delta F508-CFTR chloride channel gating. The Journal of biological chemistry, 2003, Sep-12, Volume: 278, Issue:37 Topics: Animals; Biological Transport; Cell Line; Colforsin; Cricetinae; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Genistein; Humans; Iodides; Ion Channel Gating; Kinetics; Phenylalanine; Rats; Rats, Inbred F344; Recombinant Proteins; Respiratory Mucosa; Sequence Deletion; Thermodynamics; Thyroid Gland; Transfection	2003
Involvement of CFTR in uterine bicarbonate secretion and the fertilizing capacity of sperm. Nature cell biology, 2003, Volume: 5, Issue:10 Topics: Animals; Bicarbonates; Cells, Cultured; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endometrium; Enzyme Inhibitors; Epithelial Cells; Female; Fertilization; Genistein; Humans; Male; Mice; Oocytes; Sperm Capacitation; Sperm-Ovum Interactions; Spermatozoa; Uterus	2003
The relationship between cell proliferation, Cl- secretion, and renal cyst growth: a study using CFTR inhibitors. Kidney international, 2004, Volume: 66, Issue:5 Topics: Animals; Benzoates; Cell Division; Cell Line; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dogs; Electric Conductivity; Epithelium; Genistein; Glyburide; Ion Transport; Kidney Diseases, Cystic; Nitrobenzoates; Thiazoles; Thiazolidines	2004
Heat-stable enterotoxin of Escherichia coli stimulates a non-CFTR-mediated duodenal bicarbonate secretory pathway. American journal of physiology. Gastrointestinal and liver physiology, 2005, Volume: 288, Issue:4 Topics: Animals; Bacterial Toxins; Benzoquinones; Bicarbonates; Cell Membrane; Chloride-Bicarbonate Antiporters; Colforsin; Cyclic GMP; Cystic Fibrosis; Duodenum; Enterotoxins; Enzyme Inhibitors; Escherichia coli Proteins; Genistein; In Vitro Techniques; Lactams, Macrocyclic; Mice; Natriuretic Peptides; Peptides; Protein-Tyrosine Kinases; Quinones; Rifabutin	2005
Disruption of CFTR chloride channel alters mechanical properties and cAMP-dependent Cl- transport of mouse aortic smooth muscle cells. The Journal of physiology, 2005, Oct-15, Volume: 568, Issue:Pt 2 Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta, Thoracic; Benzoates; Cells, Cultured; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Genistein; Glyburide; In Vitro Techniques; Isoproterenol; Mice; Mice, Inbred CFTR; Muscle, Smooth, Vascular; ortho-Aminobenzoates; Quinolizines; Serotonin; Thiazoles; Thiazolidines; Vasoactive Intestinal Peptide; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents	2005
Identification and functional characterization of riboflavin transporter in human-derived retinoblastoma cell line (Y-79): mechanisms of cellular uptake and translocation. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2005, Volume: 21, Issue:4 Topics: Biological Transport; Blood-Retinal Barrier; Calcium; Calmodulin; Cell Line, Tumor; Cholera Toxin; Colforsin; Drug Carriers; Enzyme Inhibitors; Genistein; Humans; Permeability; Protein Kinase C; Protein-Tyrosine Kinases; Retinoblastoma; Riboflavin; Temperature; Tritium	2005
Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening. The Journal of clinical investigation, 2005, Volume: 115, Issue:9 Topics: Animals; Cells, Cultured; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Design; Enzyme Inhibitors; Epithelial Cells; Genistein; Humans; Iodides; Luminescent Proteins; Molecular Structure; Mutation; Pyrimidinones; Respiratory Mucosa; Thiazoles	2005
Failure of cAMP agonists to activate rescued deltaF508 CFTR in CFBE41o- airway epithelial monolayers. The Journal of physiology, 2005, Dec-01, Volume: 569, Issue:Pt 2 Topics: Adenosine Triphosphate; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Genistein; HeLa Cells; Humans; Immunohistochemistry; Immunoprecipitation; Mutation; Receptors, G-Protein-Coupled; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction	2005
Forskolin-induced cell shrinkage and apical translocation of functional enhanced green fluorescent protein-human alphaENaC in H441 lung epithelial cell monolayers. The Journal of biological chemistry, 2006, Feb-24, Volume: 281, Issue:8 Topics: Amiloride; Biological Transport; Biotinylation; Brefeldin A; Carbazoles; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Epithelial Cells; Epithelial Sodium Channels; Genistein; Green Fluorescent Proteins; Humans; Immunoblotting; Immunoprecipitation; Indoles; Ions; Lung; Microscopy, Confocal; Protein Structure, Tertiary; Protein Transport; Protein-Tyrosine Kinases; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Sodium Channels; Transfection	2006
Abnormal regulatory interactions of I148T-CFTR and the epithelial Na+ channel in Xenopus oocytes. American journal of physiology. Cell physiology, 2007, Volume: 292, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Biotinylation; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Electrophysiology; Epithelial Sodium Channels; Female; Genistein; Humans; Immunoblotting; Injections; Isoleucine; Mice; Mutation; Oocytes; Patch-Clamp Techniques; RNA, Complementary; Threonine; Xenopus	2007
Dietary genistein stimulates anion secretion across female murine intestine. The Journal of nutrition, 2006, Volume: 136, Issue:11 Topics: Animals; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Estradiol; Female; Genistein; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Sex Characteristics	2006
Tyrosine phosphorylation of rabphilin during long-lasting long-term potentiation. Neuroscience letters, 2007, Mar-13, Volume: 414, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Animals; Binding Sites; Colforsin; Enzyme Inhibitors; Genistein; Hippocampus; Long-Term Potentiation; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neural Pathways; Organ Culture Techniques; Phosphodiesterase Inhibitors; Phosphorylation; Presynaptic Terminals; Synaptic Transmission; Tyrosine	2007
Expression and function of cystic fibrosis transmembrane conductance regulator in rat intrapulmonary arteries. The European respiratory journal, 2007, Volume: 30, Issue:5 Topics: Analysis of Variance; Animals; Cells, Cultured; Chloride Channels; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Genistein; Glyburide; Immunoprecipitation; Iodides; Male; Muscle, Smooth, Vascular; Phosphorylation; Pulmonary Artery; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Vasodilation	2007
Cholesterol depletion and genistein as tools to promote F508delCFTR retention at the plasma membrane. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2007, Volume: 20, Issue:5 Topics: Animals; Cell Membrane; Cholesterol; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Endocytosis; Genistein; Humans; Mice; Phenylalanine; Phosphatidylcholines	2007
Genistein potentiates protein kinase A activity in porcine coronary artery. Molecular and cellular biochemistry, 2008, Volume: 311, Issue:1-2 Topics: Adenine; Animals; Benzenesulfonates; Colforsin; Coronary Vessels; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Genistein; Humans; Muscle, Smooth, Vascular; Protein Kinase Inhibitors; Swine	2008
Activation of CFTR by UCCF-029 and genistein. Bioorganic & medicinal chemistry letters, 2008, Jul-15, Volume: 18, Issue:14 Topics: Adenosine Triphosphate; Animals; Benzoflavones; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Drug Design; Genistein; Hydrolysis; Mice; Models, Chemical; NIH 3T3 Cells; Protein Kinase Inhibitors; Transfection	2008
Genistein decreases androgen biosynthesis in rat Leydig cells by interference with luteinizing hormone-dependent signaling. Toxicology letters, 2009, Feb-10, Volume: 184, Issue:3 Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic CMP; Dose-Response Relationship, Drug; Down-Regulation; Endocrine Disruptors; Enzyme Activators; Epidermal Growth Factor; ErbB Receptors; Genistein; Leydig Cells; Luteinizing Hormone; Male; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Long-Evans; Receptors, LH; Signal Transduction; Testosterone; Tyrphostins	2009
Differential activation of the HCO(3)(-) conductance through the cystic fibrosis transmembrane conductance regulator anion channel by genistein and forskolin in murine duodenum. British journal of pharmacology, 2009, Volume: 158, Issue:5 Topics: Animals; Anions; Bicarbonates; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Duodenum; Genistein; In Vitro Techniques; Intestinal Mucosa; Ion Transport; Mice; Mice, Knockout; Mutation	2009
DeltaF508 CFTR processing correction and activity in polarized airway and non-airway cell monolayers. Pulmonary pharmacology & therapeutics, 2010, Volume: 23, Issue:4 Topics: Animals; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Genistein; Humans; Ion Transport; Phosphodiesterase Inhibitors; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred F344; Temperature	2010
Potentiation of disease-associated cystic fibrosis transmembrane conductance regulator mutants by hydrolyzable ATP analogs. The Journal of biological chemistry, 2010, Jun-25, Volume: 285, Issue:26 Topics: Adenosine Triphosphate; Amino Acid Substitution; Animals; Cell Line, Tumor; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Synergism; Genistein; Humans; Ion Channel Gating; Membrane Potentials; Mutation; Patch-Clamp Techniques; Transfection	2010
CFTR induces extracellular acid sensing in Xenopus oocytes which activates endogenous Ca²⁺-activated Cl⁻ conductance. Pflugers Archiv : European journal of physiology, 2011, Volume: 462, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Calcium; Chloride Channels; Colforsin; Cyclooxygenase Inhibitors; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Genistein; HEK293 Cells; Humans; Ion Channel Gating; Niflumic Acid; Oocytes; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Protons; Xenopus laevis	2011
Stimulation of murine intestinal secretion by daily genistein injections: gender-dependent differences. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011, Volume: 28, Issue:2 Topics: Animals; Anticarcinogenic Agents; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Genistein; Glyburide; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Sex Factors	2011
Deficit of osteoprotegerin release by osteoblasts from a patient with cystic fibrosis. The European respiratory journal, 2012, Volume: 39, Issue:3 Topics: Adenylyl Cyclases; Adult; Cells, Cultured; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genistein; Humans; Male; Osteoblasts; Osteoprotegerin; Tumor Necrosis Factor-alpha	2012
Suppression of GLUT1; a new strategy to prevent diabetic complications. Journal of cellular physiology, 2013, Volume: 228, Issue:2 Topics: Animals; beta-Crystallin B Chain; Blood Glucose; Brain; Brain Chemistry; Colforsin; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Erythrocytes; Gene Knockdown Techniques; Gene Silencing; Genistein; Glucose; Glucose Transporter Type 1; Male; Mice; Protein Kinase Inhibitors; Retina; Superoxides; Vascular Endothelial Growth Factor A	2013
Genistein stimulates jejunal chloride secretion via sex-dependent, estrogen receptor or adenylate cyclase mechanisms. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2012, Volume: 30, Issue:1 Topics: Actins; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Chlorides; Colforsin; Enzyme Activators; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fulvestrant; Genistein; Imines; Intestinal Secretions; Jejunum; Male; Mice; Mice, Inbred C57BL; Orchiectomy; Phytoestrogens; Piperidines; Pyrazoles; Sex Characteristics; Signal Transduction	2012
A novel fluorescent sensor for measurement of CFTR function by flow cytometry. Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2013, Volume: 83, Issue:6 Topics: Animals; Bacterial Proteins; Biological Transport; Cell Line; Colforsin; Cricetinae; Cystic Fibrosis Transmembrane Conductance Regulator; Flow Cytometry; Gene Expression; Genes, Reporter; Genistein; Humans; Luminescent Proteins; Mutation; Spectrometry, Fluorescence	2013
Activation of chloride secretion by isoflavone genistein in endometrial epithelial cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2013, Volume: 32, Issue:5 Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Bumetanide; Cell Membrane Permeability; Cells, Cultured; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Egtazic Acid; Endometrium; Epithelial Cells; Estradiol; Female; Fulvestrant; Genistein; Glyburide; Swine; Uridine Triphosphate	2013
[Polymethoxylated flavonoids activate cystic fibrosis transmembrane conductance regulator chloride channel]. Sheng li xue bao : [Acta physiologica Sinica], 2015, Apr-25, Volume: 67, Issue:2 Topics: Animals; Colforsin; Colon; Cystic Fibrosis Transmembrane Conductance Regulator; Flavones; Flavonoids; Genistein; Intestinal Mucosa; Mice; Rats	2015
Differential thermostability and response to cystic fibrosis transmembrane conductance regulator potentiators of human and mouse F508del-CFTR. American journal of physiology. Lung cellular and molecular physiology, 2019, 07-01, Volume: 317, Issue:1 Topics: Adenosine Triphosphate; Aminophenols; Aminopyridines; Animals; Base Sequence; Benzodioxoles; Chloride Channel Agonists; CHO Cells; Colforsin; Cricetulus; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Gene Expression; Genistein; Ion Transport; Mice; NIH 3T3 Cells; Patch-Clamp Techniques; Protein Stability; Quinolones; Sequence Deletion; Species Specificity; Temperature; Transgenes	2019