colforsin has been researched along with dinoprostone in 538 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 101 (18.77) | 18.7374 |
| 1990's | 278 (51.67) | 18.2507 |
| 2000's | 123 (22.86) | 29.6817 |
| 2010's | 32 (5.95) | 24.3611 |
| 2020's | 4 (0.74) | 2.80 |
| Authors | Studies |
|---|---|
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Hata, F; Takeuchi, T; Yagasaki, O | 1 |
| Judd, AM; MacLeod, RM | 1 |
| Amiel, C; Friedlander, G; Herman, P; Huy, PT | 1 |
| Akahoshi, T; Hayashi, H; Kato, K; Marunouchi, T; Onozaki, K; Takii, T | 1 |
| Alava, MA; Bonvini, E; Conti, A; DeBell, KE; Hoffman, T | 1 |
| Davies, R; Jones, TH; Justice, SK; Kennedy, RL; Lemoine, NR | 1 |
| Birkenhäger, JC; Pols, HA; van den Bemd, GJ; van Leeuwen, JP; Vink-van Wijngaarden, T | 1 |
| Feniuk, W; Humphrey, PP; McCormick, JD; Sumner, MJ | 1 |
| Fang, MA; Hahn, TJ; Kujubu, DA | 1 |
| Hikida, M; Ohmori, H; Takai, T | 1 |
| Elzinga, L; Grant, M; Grantham, JJ; Sharma, M; Swan, S; Torres, VE; Ye, M | 1 |
| Armstrong, JW; Bourke, JR; Cragoe, EJ; Huxham, GJ; Manley, SW | 1 |
| Campbell, WB; Farrar, MA; Magness, RR; Shaul, PW | 1 |
| Lew, DB; Malik, KU; Nadel, GL | 1 |
| Bourne, HR; Conklin, BR; Wong, YH | 1 |
| Ayton, B; Chapman, J; Hardcastle, J; Hardcastle, PT; MacNeil, S | 1 |
| Classen, M; Offermanns, S; Rosenthal, W; Schepp, W; Schmidtler, J; Schusdziarra, V | 1 |
| Chang, EB; Ciancio, MJ; Dhar, A; Vitiritti, L | 1 |
| Fertel, RH; Kniss, DA; Su, HC | 1 |
| Schröder, H; Schrör, K; Strobach, H | 1 |
| Hayashi, Y; Honda, A; Ichikawa, A; Namba, T; Narumiya, S; Negishi, M; Sugimoto, Y | 1 |
| Bockman, RS; Guidon, PT; Rapuano, BE; Salvatori, R | 1 |
| Pahapill, PA; Schlichter, LC | 1 |
| Daykin, K; Hall, IP; Townsend, P; Widdop, S | 1 |
| Herschman, HR; Kujubu, DA | 1 |
| Märki, F; Pfeilschifter, J; Schalkwijk, C; van den Bosch, H | 1 |
| Canalis, E; Centrella, M; McCarthy, TL; Raisz, LG | 1 |
| Raufman, JP; Singh, L | 1 |
| Bismuth, G; Cefai, D; Christensen, SB; Debre, P; Gouy, H | 1 |
| Bismuth, G; Debré, P; Feuillard, J; Gouy, H; Körner, M; Lee, LM | 1 |
| Arner, P; Engfeldt, P; Goldinger, M; Marcus, C | 1 |
| Birkenhäger, JC; Pols, HA; Schilte, JP; van Leeuwen, JP; Visser, TJ | 1 |
| Michelson, S; Paya, CV; Virelizier, JL | 1 |
| Bryman, I; Norström, A | 1 |
| Scarpa, A; Wiener, E | 1 |
| Ardaillou, N; Ardaillou, R; Blanchard, A; Savic, V; Stefanovic, V; Vlahovic, P | 1 |
| Frondoza, C; Kiebzak, GM; Lajeunesse, D; Sacktor, B | 1 |
| Holter, W; Knapp, W; Majdic, O; Sunder-Plassmann, R | 1 |
| Bensussan, A; Bihoreau, C; Corvaïa, N; Degos, L; Enjalbert, A; Heurtier, A; Kordon, C | 1 |
| Jessop, JJ; Taplits, MS | 1 |
| Sung, SS; Walters, JA | 1 |
| Amiel, C; Bernard, C; Ferrary, E; Friedlander, G; Sterkers, O | 1 |
| Bowers, PN; Klein-Nulend, J; Raisz, LG | 1 |
| Koren, R; Liberman, A; Narinsky, R; Novogrodsky, A; Ravid, A; Rotem, C | 1 |
| Pedersen, PS | 1 |
| Birkenhäger, JC; Buurman, CJ; Pols, HA; Schilte, JP; van Leeuwen, JP | 1 |
| Chen, AB; Fei, DT; Gross, MC; Lofgren, JL; Mora-Worms, M | 1 |
| Bridges, RJ; Frizzell, RA; Venglarik, CJ | 1 |
| Collins, BJ; Cuttler, L; Staib, NE; Szabo, M | 1 |
| Chabardès, D; Montégut, M; Siaume-Perez, S; Zhou, Y | 1 |
| Chaudhari, A; Gupta, S; Kirschenbaum, MA | 1 |
| De Mey, JG; Dijkstra, EH; Vrijdag, MJ | 1 |
| De Mey, JG; Heesen, BJ | 1 |
| Farndale, RW; Martin, BR; Meikle, MC; Sandy, JR | 1 |
| Shikada, K; Tanaka, S; Yamamoto, A | 1 |
| Lowe, C; Skinner, SJ; Somervell, CE | 1 |
| Kennedy, TG; Yee, GM | 1 |
| Grenfell, S; Ray, K; Rollins, P; Sadler, H; Smithers, N; Solari, R; Thompson, N; Witham, S | 1 |
| Khademazad, M; Loessberg, P; Muallem, S; Whisenant, N; Zhang, BX | 1 |
| Gupta, S; Schlondorff, D; Shen, Z; Singhal, PC | 1 |
| Levine, JD; Taiwo, YO | 1 |
| Baylink, DJ; Mohan, S | 1 |
| Chatzipanteli, K; Orford, M; Saggerson, D; Shepherd, J | 1 |
| Beil, W; Bersimbaev, R; Sewing, KF | 1 |
| Betz, M; Fox, BS | 1 |
| Burnham, DN; Lambeth, JD; Olson, SC; Tyagi, SR | 1 |
| Beusenberg, FD; Bonta, IL; Leurs, R; van Amsterdam, JG; van Schaik, A | 1 |
| Märki, F; Pfeilschifter, J; Schalkwijk, C; van den Bosch, H; Vervoordeldonk, M | 1 |
| Jackson, CA; Peterson, JW; Reitmeyer, JC | 1 |
| Davis, LS; Lipsky, PE; Minakuchi, R; Wacholtz, MC | 1 |
| Keenan, CM; Rangachari, PK | 1 |
| Peter, RE; Rosenblum, PM; Yu, KL | 1 |
| Arita, H; Kurihara, H; Nakano, T; Takasu, N | 1 |
| Baba, A; Fukuda, K; Kuchii, M; Masuyama, Y; Nishio, H; Nishio, I; Ueyama, T; Yoshikawa, A; Yoshikawa, H | 1 |
| Barsony, J; Marx, SJ | 1 |
| Biddulph, DM; Capehart, AA; Dozier, MM; Julian, NC | 1 |
| Raud, J | 1 |
| Hurme, M | 1 |
| Berl, T; Dillingham, MA; Veis, JH | 1 |
| Granot, I; Hurwitz, S; Pines, M | 1 |
| Laskin, DL; Laskin, JD; Robertson, FM; Sirak, AA | 1 |
| Hughes, JP; Prentice, DA; Rayhel, EJ; Svihla, DA | 1 |
| Chao, W; Hanahan, DJ; Liu, HL; Olson, MS; Zhou, WG | 1 |
| Blackmore, PF; Graber, SE; Kelley, LL; Stewart, SJ | 1 |
| Iizuka, H; Takahashi, H; Tamura, T; Tsutsui, M | 1 |
| Hurme, M; Ronni, T; Serkkola, E; Silvennoinen, O | 1 |
| Kirkland, SC | 1 |
| Gutierrez, GE; Hewlett, EL; Katz, MS; Manning, DR; Mundy, GR | 1 |
| McArdle, CA | 1 |
| Feyen, JH; Nijweide, PJ; van der Plas, A | 1 |
| Costa, ME; Katz, KH; Ojeda, SR; Urbanski, HF | 1 |
| Bonjour, JP; Caverzasio, J; Rizzoli, R | 1 |
| Catherwood, BD; Chenoweth, DE; Rubin, JE | 1 |
| Dunn, MJ; Sato, M | 1 |
| Labrie, F; Simard, J | 1 |
| Hakeda, Y; Kumegawa, M; Kurihara, N; Maeda, N; Natakani, Y; Yoshino, T | 1 |
| Olansky, L; Shew, RL; Sutton, JK; Yee, JA | 1 |
| Alvarez, R; Amirian, DA; Chen, MC; Soll, AH; Toomey, M | 1 |
| Fredholm, BB; Lerner, U; Ransjö, M | 1 |
| Barnea, A; Cho, G | 1 |
| Barker, S; Cassity, N; Martinez, JR | 1 |
| Donoff, B; McWade, D; Rangachari, PK | 1 |
| Frizzell, RA; Halm, DR; Rechkemmer, GR; Schoumacher, RA | 1 |
| Emoto, T; Hiraiwa, M; Kasai, K; Shimoda, S | 1 |
| Hurwitz, S; Pines, M | 1 |
| Frizzell, RA; Halm, DR; Rechkemmer, G; Schoumacher, RA | 1 |
| Bourke, JR; Gerard, C; Huxham, GJ; Manley, SW; Matainaho, T; Mauchamp, J; Pearson, J; Verrier, B | 1 |
| Soll, AH; Toomey, M | 1 |
| Armstrong, DT; Barbe, GJ; Calaresu, FR; Morley, P | 1 |
| Schoen, HF | 1 |
| Seidler, U; Sewing, KF | 1 |
| Gaur, A; Phipps, RP; Quill, H | 1 |
| Chiba, T; Fujita, T; Inui, T; Kadowaki, S; Morishita, T; Nakamura, A; Yamaguchi, A; Yamatani, T | 1 |
| Hayaishi, O; Ito, S; Negishi, M | 1 |
| Fredholm, BB; Kvanta, A; Nordstedt, C; Van der Ploeg, I | 1 |
| Auberger, P; Aussel, C; Fehlmann, M; Mary, D; Peyron, JF | 1 |
| Dolci, W; Fischer, JA; Gerber-Wicht, C; Vallotton, MB | 1 |
| Mitsuhashi, M; Mitsuhashi, T; Payan, DG | 1 |
| Hurwitz, S; Pines, M; Yosif, B | 1 |
| Andersson, RG; Johnsen, SA; Olding, LB; Papadogiannakis, N; Rosberg, S | 1 |
| Miledi, R; Woodward, RM | 1 |
| Adachi, I; Connolly, N; Suzuki, T | 1 |
| Davis, BB; Rapp, NS; Spry, LA; Thomasson, DL; Zenser, TV | 1 |
| Davidson, SR; Hollister, MC; Phernetton, TM; Rankin, JH; Reid, DL | 1 |
| Amiel, C; Friedlander, G; Giocondi, MC; Le Grimellec, C | 1 |
| Molskness, TA; Stouffer, RL; Vandevoort, CA | 1 |
| Jacobson, B; Lerner, A; Miller, RA | 1 |
| Greene, RM; Jones, J | 1 |
| Bottari, SP; Goldfien, A; Jacobs, MM; Riemer, RK; Roberts, JM; Wu, YY | 1 |
| García-Sáinz, JA; Juárez-Ayala, J | 1 |
| Gunst, SJ; Stropp, JQ | 1 |
| Higgs, NB; Lees, M; Tonge, A; Turnberg, LA; Warhurst, G | 1 |
| Keck, E; van Valen, F | 2 |
| Atkinson, SJ; Farndale, RW; Meghji, S; Meikle, MC; Pennington, SR; Sandy, JR | 1 |
| Banchereau, J; Cabrillat, H; de Vries, JE; Galizzi, JP; Ménétrier, C; Rousset, F | 1 |
| Hashida, T; Imashuku, S; Todo, S | 1 |
| Kumegawa, M; Kusaka, M; Oshima, T; Yamamoto, S; Yokota, K | 1 |
| Bismuth, G; Debre, P; Gouy, H; le Gouvello, S; Theodorou, I | 1 |
| Bonjour, JP; Rizzoli, R | 1 |
| Enna, SJ; Karbon, EW; Shenolikar, S | 1 |
| Lees, M; Smith, G; Turnberg, L; Warhurst, G | 1 |
| Gautvik, KM; Gordeladze, JO; Sletholt, K; Thorn, NA | 1 |
| Akahoshi, T; Matsushima, K; Oppenheim, JJ | 1 |
| Hakeda, Y; Ikeda, E; Kumegawa, M; Kurihara, N; Maeda, N; Nakatani, Y | 1 |
| Gerard, C; Mauchamp, J; Verrier, B | 1 |
| Fiscus, RR; Mayer, SE; Peterson, SM; Rinard, GA; Torphy, TJ; Zheng, C | 1 |
| Bauer, C; Jelkmann, W; Kurtz, A; Pfeilschifter, J | 1 |
| Do Khac, L; Harbon, S; Mokhtari, A; Tanfin, Z | 1 |
| Ishikawa, S; Kuzuya, T; Saito, T | 2 |
| Ishitoya, J; Nagai, Y; Takenawa, T | 1 |
| Ishitoya, J; Takenawa, T | 1 |
| Aublin, JL; Champion, S; Haye, B; Jacquemin, C; Lambert, B | 1 |
| Rosenfeld, GC | 1 |
| Fredholm, BB; Jonzon, B; Lindström, K | 1 |
| Casavola, V; Svelto, M | 1 |
| Conn, PM; Costa, ME; Katz, KH; Ojeda, SR; Urbanski, HF | 1 |
| Classen, M; Schepp, W; Schusdziarra, V; Steffen, B | 1 |
| Vallotton, MB; Wuthrich, RP | 1 |
| Mochan, E; Newton, R; Uhl, J | 1 |
| Do Khac, L; Harbon, S; Mokhtari, A | 1 |
| Hays, S; Jacobson, HR; Kokko, JP | 1 |
| Hansen, JA; June, CH; Ledbetter, JA; Martin, PJ; Parsons, M; Rabinovitch, PS | 1 |
| Kim, K; Ramirez, VD | 1 |
| Malemud, CJ; Mills, TM; Papay, RS | 1 |
| Jelinek, DF; Lipsky, PE; Simkin, NJ | 1 |
| Martin, TJ; Moseley, JM; Nicholson, GC; Yates, AJ | 1 |
| Asem, EK; Hertelendy, F; Todd, H | 1 |
| Box, RJ; Portenier, M; Staehelin, M | 1 |
| Amiel, C; Friedlander, G | 1 |
| Harbon, S; Tanfin, Z | 1 |
| Daly, JW; Hollingsworth, EB | 1 |
| Dubyak, GR; Moore, JJ; Moore, RM; Vander Kooy, D | 1 |
| Hansen, TR; Randel, RD; Welsh, TH | 1 |
| Calkins, JH; Lin, T; Nankin, HR; Sigel, MM | 1 |
| Brenner, BM; Hebert, SC; Nadler, SP | 1 |
| Bauer, C; Brown, CD; Kurtz, A; Pfeilschifter, J | 1 |
| Cuthbert, AW; Wong, PY | 1 |
| Joost, HG; Steinfelder, HJ | 1 |
| Cuthbert, AW; George, AM; MacVinish, L | 1 |
| Kurosawa, H; Satoh, H; Satoh, S; Suzuki, J; Yatsu, T | 1 |
| Biondi, C; Borasio, PG; Capuzzo, A; Ferretti, ME; Trevisani, A | 1 |
| Andreoli, TE; Culpepper, RM | 1 |
| Böhlen, P; Brazeau, P; Esch, F; Guillemin, R; Ling, N; Mougin, C | 1 |
| Davis, BB; Rapp, NS; Spry, LA; Zenser, TV | 1 |
| Dalaker, K; Prydz, H | 1 |
| Burka, JF | 1 |
| Baukal, AJ; Catt, KJ; Darbon, JM; Knecht, M; Ranta, T | 1 |
| Burka, JF; Saad, MH | 1 |
| Barnes, PJ; Giembycz, MA; Meja, K; Seldon, PM | 1 |
| Bertram, P; Scutt, A; Zeschnigk, M | 1 |
| Li, X; Nemenoff, RA; Schrier, RW; Zarinetchi, F | 1 |
| Cole, OF; Elder, MG; Seki, H; Sullivan, MH | 1 |
| Kawakami, S; Miyazaki, K; Okamura, H; Tanaka, N | 1 |
| Gögelein, H; Siemer, C | 2 |
| Gohda, E; Iwao, M; Kataoka, H; Matsunaga, T; Takebe, T; Wu, YL; Yamamoto, I | 1 |
| Kotoyori, J; Kozawa, O; Oiso, Y; Tokuda, H | 2 |
| Florio, C; Heisler, S; Martin, JG; Styhler, A | 1 |
| Ingram, SL; Williams, JT | 2 |
| Dunn, MJ; Herman, WH; Simonson, MS | 1 |
| DiBattista, JA; Jolicoeur, FC; Martel-Pelletier, J; Morin, N; Pelletier, JP | 1 |
| Baier, LD; Daphna-Iken, D; DuMaine, J; Morrison, AR; Srivastava, SK; Tetsuka, T | 1 |
| Borch, RF; Patil, RR | 1 |
| Bear, CE; Krolczyk, AJ; Lai, PF; Schimmer, BP | 1 |
| Albelda, SM; Lazaar, AL; Panettieri, RA; Puré, E | 1 |
| Calzada-Wack, JC; Goretzki, M; Johnson, JP; Pietsch, A; Weber, C; Ziegler-Heitbrock, HW | 1 |
| Bens, M; Cluzeaud, F; Vandewalle, A; Wu, MS | 1 |
| Bornefalk, E; Johansson, AG; Ljunggren, O; Ljunghall, S; Nilsson, K | 1 |
| Diener, M; Strabel, D | 1 |
| Buchmüller-Rouiller, Y; Corradin, SB; Mauël, J; Ransijn, A | 1 |
| Gobbetti, A; Zerani, M | 1 |
| Bourette, RP; Carlberg, K; Chen, AR; Myles, GM; Rohrschneider, LR | 1 |
| Chik, CL; Ho, AK; Karpinski, E; Kovacs, CS; Li, B | 1 |
| Israël, L; Magnien, V; Planchon, P; Starzec, AB; Veber, N | 1 |
| Ashbaugh, P; Bhattacharyya, SN; Manna, B | 1 |
| Leeb-Lundberg, F; McAllister, BS; Mellonig, JT; Olson, MS | 1 |
| Kelly, K; Knox, KA | 1 |
| Maggi, R; Martini, L; Pimpinelli, F; Piva, F | 1 |
| DiBattista, JA; Iwata, K; Martel-Pelletier, J; Pelletier, JP; Zafarullah, M | 1 |
| Daphna-Iken, D; Morrison, AR; Srivastava, SK; Tetsuka, T | 1 |
| Asahi, M; Minami, Y; Qin, S; Sada, K; Tanaka, Y; Tsubokawa, M; Yamamura, H | 1 |
| Okamoto, H; Takano, M; Yayama, K; Yokoyama, K | 1 |
| Caflisch, CR; George, T; Good, DW | 1 |
| Asghari, V; Buchwaldt, S; Jovanovic, V; Paterson, A; Sanyal, S; Van Tol, HH | 1 |
| Collin, JP; Pontoire, C; Van Camp, G; Voisin, P | 1 |
| Adashi, EY; Resnick, CE; Rosenfeld, RG; Tedeschi, C | 1 |
| Bilodeau, S; Fortier, MA; Sirard, MA | 1 |
| Boumpas, DT; Kincaid, RL; Paliogianni, F | 1 |
| Bascands, JL; Girolami, JP; Pecher, C | 1 |
| Arima, N; Chiba, T; Kinoshita, Y; Nakamura, A; Yamashita, Y | 1 |
| McGrath, JC; Smith, GC | 2 |
| Good, DW | 1 |
| Herman, P; Marianowski, R; Martin, F; Tran Ba Huy, P; Tu, TY | 1 |
| Barry, T; Delamere, F; Holland, E; Knox, A; Pavord, I | 1 |
| Alander, CB; Delman, BN; Kawaguchi, H; Pilbeam, CC; Raisz, LG; Voznesensky, O | 1 |
| Esteva, F; Lanas, AI; Nerín, J; Sáinz, R | 1 |
| Daculsi, R; Gualde, N; Vaillier, D | 1 |
| Ashbaugh, P; Bhattacharyya, SN; Kaufman, B; Manna, B | 1 |
| Antonicelli, F; Claisse, D; Delemer, B; Elbtaouri, H; Haye, B | 1 |
| Dobber, R; Nagelkerken, L; Schuitemaker, J; Tielemans, M; van den Bergh, P | 1 |
| Aarab, L; Chabardès, D; Siaume-Perez, S | 1 |
| Benovic, JL; Higgins, NC; Kelsen, SG; Mardini, IA; Zhou, S | 1 |
| Benovic, JL; Kelsen, SG; Penn, RB | 1 |
| Casinghino, S; Centrella, M; McCarthy, TL | 1 |
| Satriano, J; Schlondorff, D | 1 |
| Europe-Finner, GN; López Bernal, A; Phaneuf, S; Tolkovsky, AM; Watson, SP | 1 |
| Cohen, AJ; Fishman, JB; Silbiger, SR; Stoff, JS | 1 |
| Chavali, SR; Forse, RA; Zhong, WW | 1 |
| Asano, T; Ichikawa, A; Irie, A; Namba, T; Negishi, M; Sugimoto, Y | 1 |
| Bartik, MM; Bauman, GP; Brooks, WH; Roszman, TL | 1 |
| Eaton, DC; Kokko, KE; Ling, BN | 1 |
| César, KR; Magaldi, AJ; Yano, Y | 1 |
| Koda, H; Kumazawa, T; Minagawa, M; Mizumura, K | 1 |
| Azevedo, I; Bachelet, M; de Blic, J; Galoppin, L; Scheinmann, P; Vargaftig, BB | 1 |
| Harazono, A; Ichikawa, A; Negishi, M; Sugimoto, Y | 1 |
| Heller, EJ; Heppel, LA; Huang, NN; Wang, DJ | 1 |
| Kavanaugh, AF; Lipsky, PE; Oppenheimer-Marks, N | 1 |
| Grimaldi, M; Navarra, P; Pozzoli, G; Preziosi, P; Schettini, G | 1 |
| Alander, CB; Hakeda, Y; Kawaguchi, H; Pilbeam, CC; Raisz, LG; Voznesensky, O | 1 |
| Hanevold, CD; Jordan, SC; Yamaguchi, DT | 1 |
| Fukuda, K; Matsumura, F; Tanaka, S | 1 |
| Joyce, NC; Meklir, B | 1 |
| Boneh, A; Brenner, T; Shohami, E | 1 |
| Miyazaki, K; Mizutani, H; Okamura, H; Tanaka, N; Tashiro, H | 1 |
| Hinko, A; Soloff, MS | 2 |
| Gomberg-Malool, S; Levitzki, A; Orly, J; Posner, I; Re'em, Y; Ziv, R | 1 |
| Ikeda, K; Inoue, D; Matsumoto, T; Ogata, E; Okazaki, R | 1 |
| Daykin, K; Hall, IP; Widdop, S | 1 |
| Case, RM; Evans, RL; Lau, KR | 1 |
| Dessing, M; Lanzavecchia, A; Valitutti, S | 1 |
| Katz, S; Mok, W; Phaneuf, S; Salari, H; Wong, S | 1 |
| Kimura, N; Nagata, N; Shimada, N; Yasutomo, Y | 1 |
| De Felici, M; Dolci, S; Pesce, M | 1 |
| Ichikawa, A; Irie, A; Narumiya, S; Negishi, M; Sugimoto, Y | 1 |
| Banchereau, J; Garrone, P | 1 |
| Faili, A; Hatmi, M; Randon, J; Vargaftig, BB | 1 |
| Heppel, LA; Huang, NN; Wang, DJ | 1 |
| Armerding, D; Hren, A | 1 |
| Borzecki, JS; McKay, AJ; Peterson, LN | 1 |
| Bos, JD; Kaliński, P; Kapsenberg, ML; Snijdewint, FG; Wierenga, EA | 1 |
| Bonjour, JP; Law, F; Rizzoli, R | 1 |
| Collins, PL; Moore, JJ; Moore, RM | 1 |
| Black, C; Curry, C; Emala, C; Hirshman, CA; Levine, MA | 1 |
| Fischer, W; Schudt, C; Wendel, A | 1 |
| Beverley, PC; Cayeux, SJ; Dörken, B; Schultz, R | 1 |
| Hata, Y; Hiraishi, H; Kawabe, T; Mutoh, H; Ota, S; Shiina, S; Sugimoto, T; Terano, A; Yoshiura, K | 1 |
| Muroi, M; Suzuki, T | 1 |
| Kotoyori, J; Kozawa, O; Oiso, Y; Suzuki, A; Tokuda, H | 1 |
| Nash, MS; Osborne, NN | 1 |
| al-Zadjali, K; Ohia, SE; Opere, C; Tang, L | 1 |
| Hashimoto, Y; Iizuka, H; Ishida-Yamamoto, A; Takahashi, H | 1 |
| Bos, MP; Feyen, JH; Herrmann-Erlee, MP; Van der Meer, JM | 1 |
| Delikat, SE; Galvani, DW; Zuzel, M | 1 |
| Bolognese, B; Marshall, LA; McCord, M | 1 |
| Ehlert, FJ; Gerstin, EH | 1 |
| Benishin, CG; Karpinski, E; Ren, J | 1 |
| Handschumacher, RE; Li, W | 1 |
| Barnes, PJ; Haddad, EB; Mak, JC; Rousell, J | 1 |
| Benya, PD; Fu, YH; Hahn, TJ; Lowe, GN; McDougall, S; Polendo, R; Williams, A | 1 |
| Canalis, E; Pash, JM | 1 |
| Grunstein, MM; Hakonarson, H; Herrick, DJ; Serrano, PG | 2 |
| Bissonnette, EY | 1 |
| McCarthy, LM; O'Neill, LA | 1 |
| Baldi, A; Davio, C; Lemos, B; Mladovan, A; Rivera, E; Shayo, C | 1 |
| Barnes, PJ; Belvisi, MG; Giembycz, MA; Patel, HJ; Takahashi, T | 1 |
| Costa, T; Levi, G; Patrizio, M; Riitano, D | 1 |
| Ainsworth, MA; Amelsberg, A; Amelsberg, M; Hogan, DL; Isenberg, JI | 1 |
| Edwards, SC; Hinsch, GW; Spaziani, EP | 1 |
| Body, JJ; Lacroix, M; Siwek, B | 1 |
| Hastings, MH; McNulty, S; Morgan, PJ; Ross, AW; Shiu, KY | 1 |
| Koda, H; Kumazawa, T; Mizumura, K | 1 |
| Bevan, S; Docherty, RJ; England, S | 1 |
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| Akamizu, T; Ariyasu, H; Bando, M; Dote, K; Hosoda, H; Hosoda, K; Iwakura, H; Kangawa, K; Koyama, H; Kusakabe, T; Nakao, K; Son, C | 1 |
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2 review(s) available for colforsin and dinoprostone
| Article | Year |
|---|---|
Forskolin modulates cyclic AMP generation in the rat myometrium. Interactions with isoproterenol and prostaglandins E2 and I2.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; Epoprostenol; Female; In Vitro Techniques; Isoproterenol; Membranes; Myometrium; Propranolol; Prostaglandins E; Rats; Rats, Inbred Strains | 1985 |
Nonselective cation channels in cells of the crypt-base of rat distal colon.
Topics: Animals; Cations; Cell Membrane; Colforsin; Colon; Dinoprostone; Epithelial Cells; Epithelium; Flufenamic Acid; Humans; In Vitro Techniques; Ion Channels; Meglumine; Membrane Potentials; Muscle, Smooth; Rats; Sodium | 1993 |
536 other study(ies) available for colforsin and dinoprostone
| Article | Year |
|---|---|
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Role of cyclic AMP in prostaglandin-induced modulation of acetylcholine release from the myenteric plexus of guinea pig ileum.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Colforsin; Cyclic AMP; Dinoprostone; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth; Myenteric Plexus; Nicotine; Prostaglandins | 1992 |
Adrenocorticotropin increases interleukin-6 release from rat adrenal zona glomerulosa cells.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Female; Interleukin-1; Interleukin-6; Rats; Rats, Inbred Strains; Zona Glomerulosa | 1992 |
Ion transport by primary cultures of Mongolian gerbil middle ear epithelium.
Topics: Amiloride; Animals; Arginine Vasopressin; Biological Transport; Bradykinin; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Dinoprostone; Ear, Middle; Epithelium; Gerbillinae; Glucagon; Histamine; Indomethacin; Isoproterenol; Male; Mannitol; Microscopy, Electron; Parathyroid Hormone; Sodium | 1992 |
Interleukin-1 up-regulates transcription of its own receptor in a human fibroblast cell line TIG-1: role of endogenous PGE2 and cAMP.
Topics: Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Fibroblasts; Humans; Interleukin-1; Receptors, Immunologic; Receptors, Interleukin-1; RNA, Messenger; Transcription, Genetic; Up-Regulation | 1992 |
Increased intracellular cyclic AMP inhibits inositol phospholipid hydrolysis induced by perturbation of the T cell receptor/CD3 complex but not by G-protein stimulation. Association with protein kinase A-mediated phosphorylation of phospholipase C-gamma 1
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Cattle; CD3 Complex; Cell Membrane Permeability; Cholera Toxin; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Diterpenes; Down-Regulation; Enzyme Activation; GTP-Binding Proteins; Hydrolysis; Inositol Phosphates; Intracellular Fluid; Isoenzymes; Mice; Mice, Nude; Phospholipids; Phosphorylation; Protein Kinases; Receptors, Antigen, T-Cell; Stimulation, Chemical; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; Type C Phospholipases | 1992 |
Release of interleukin-6 by human thyroid epithelial cells immortalized by simian virus 40 DNA transfection.
Topics: Cell Line; Colforsin; Dinoprostone; Epidermal Growth Factor; Epithelium; Humans; Interferon-gamma; Interleukin-1; Interleukin-6; Simian virus 40; Stimulation, Chemical; Thyroid Gland; Thyrotropin; Transfection; Tumor Necrosis Factor-alpha | 1992 |
Regulation of 1,25-dihydroxyvitamin D3 receptor gene expression by parathyroid hormone and cAMP-agonists.
Topics: Animals; Blotting, Northern; Bucladesine; Calcimycin; Calcitriol; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Gene Expression Regulation, Neoplastic; Kinetics; Osteosarcoma; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Protein Biosynthesis; Proteins; Rats; Receptors, Calcitriol; Receptors, Steroid; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Teriparatide; Transcription, Genetic | 1992 |
Studies on the mechanism of 5-HT1 receptor-induced smooth muscle contraction in dog saphenous vein.
Topics: Adenylyl Cyclase Inhibitors; Animals; Brain Chemistry; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Dogs; Female; In Vitro Techniques; Indoles; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Receptors, Serotonin; Saphenous Vein; Serotonin; Serotonin Antagonists; Sulfonamides; Sumatriptan; Vasoconstrictor Agents | 1992 |
The effects of prostaglandin E2, parathyroid hormone, and epidermal growth factor on mitogenesis, signaling, and primary response genes in UMR 106-01 osteoblast-like cells.
Topics: Animals; Bone Neoplasms; Calcium; Colforsin; Cyclic AMP; Cycloheximide; Dinoprostone; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Immediate-Early Proteins; Inositol Phosphates; Mitosis; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinases; Radioimmunoassay; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thymidine; Transcription Factors; Tritium; Tumor Cells, Cultured; Zinc Fingers | 1992 |
Selective regulation of antigen-specific IgE response by cyclic AMP level in murine lymphocytes.
Topics: Animals; Antigens; B-Lymphocytes; Bucladesine; Colforsin; Cyclic AMP; Dideoxyadenosine; Dinoprostone; Female; Haptens; Hemocyanins; Immunoglobulin E; Immunoglobulin G; Immunoglobulin M; In Vitro Techniques; Mice; Mice, Inbred BALB C | 1992 |
Cyst fluid from human autosomal dominant polycystic kidneys promotes cyst formation and expansion by renal epithelial cells in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Body Fluids; Cell Division; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Dogs; Epithelial Cells; Epithelium; Growth Substances; Humans; Interleukins; Kidney; Organ Culture Techniques; Peptides; Polycystic Kidney, Autosomal Dominant | 1992 |
Chloride conductance of apical membrane in cultured porcine thyroid cells activated by cyclic AMP.
Topics: Animals; Calcimycin; Carrier Proteins; Cell Membrane; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Dinoprostone; Electric Conductivity; Membrane Proteins; Sodium-Potassium-Chloride Symporters; Swine; Thyroid Gland; Thyrotropin | 1992 |
Oxygen modulates prostacyclin synthesis in ovine fetal pulmonary arteries by an effect on cyclooxygenase.
Topics: Animals; Calcimycin; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Epoprostenol; Isoproterenol; Muscle, Smooth, Vascular; Oxygen; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins H; Pulmonary Artery; Signal Transduction; Swine | 1992 |
Prostaglandin E2 synthesis elicited by adrenergic stimuli in guinea pig trachea is mediated primarily via activation of beta 2 adrenergic receptors.
Topics: Albuterol; Animals; Arachidonic Acid; Butoxamine; Colforsin; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Dobutamine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Practolol; Receptors, Adrenergic, beta; Time Factors; Trachea | 1992 |
Gz-mediated hormonal inhibition of cyclic AMP accumulation.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dinoprostone; Dopamine; Gene Expression Regulation; GTP-Binding Proteins; Hormones; In Vitro Techniques; Lysophospholipids; Pertussis Toxin; Quinoxalines; Rats; Signal Transduction; Transfection; Virulence Factors, Bordetella | 1992 |
Calcium-calmodulin-dependent activation of adenylate cyclase in prostaglandin-induced electrically-monitored intestinal secretion in the rat.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Bucladesine; Calcium; Calmodulin; Colforsin; Cyclic AMP; Dinoprostone; Electrophysiology; Enzyme Activation; Intestinal Mucosa; Intestine, Small; Male; Rats; Rats, Inbred Strains; Sulfonamides | 1992 |
Pertussis toxin reverses prostaglandin E2- and somatostatin-induced inhibition of rat parietal cell H(+)-production.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Aminopyrine; Animals; Colforsin; Dinoprostone; Female; GTP-Binding Proteins; Histamine; Parietal Cells, Gastric; Pertussis Toxin; Protons; Rats; Rats, Inbred Strains; Somatostatin; Virulence Factors, Bordetella | 1992 |
Endotoxin-induced alterations in rat colonic water and electrolyte transport.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bethanechol; Bethanechol Compounds; Biological Transport; Chlorine; Colforsin; Colon; Diarrhea; Dinoprostone; Endotoxins; Ileum; Insulin; Jejunum; Male; Protein Kinases; Rats; Rats, Sprague-Dawley; Sodium; Theophylline; Vasoactive Intestinal Peptide; Water-Electrolyte Balance | 1992 |
Catecholamines modulate epidermal growth factor-induced prostaglandin E2 production in amnion-like (WISH) cells by means of a cyclic adenosine monophosphate-dependent pathway.
Topics: 1-Methyl-3-isobutylxanthine; Amnion; Catecholamines; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Dopamine; Epidermal Growth Factor; Epinephrine; Female; Humans; Norepinephrine; Propranolol | 1992 |
Nitric oxide but not prostacyclin is an autocrine endothelial mediator.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Endothelium, Vascular; Epoprostenol; Iloprost; Nitric Oxide; omega-N-Methylarginine; Second Messenger Systems; Swine | 1992 |
Cloning and expression of a cDNA for mouse prostaglandin E receptor EP3 subtype.
Topics: Alprostadil; Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; DNA; Gene Expression; Humans; Mice; Molecular Sequence Data; Prostaglandins; Prostaglandins E, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; RNA; Sequence Homology, Nucleic Acid; Thromboxanes; Transfection | 1992 |
Prostaglandin E1 inhibits collagenase gene expression in rabbit synoviocytes and human fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Cell Line; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Fibroblasts; Gene Expression; Humans; Microbial Collagenase; Promoter Regions, Genetic; Rabbits; RNA, Messenger; Synovial Membrane | 1992 |
Modulation of potassium channels in intact human T lymphocytes.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Calcium; Colforsin; Cyclic AMP; Cytoplasm; Dinoprostone; Electric Stimulation; Histamine; Humans; Isoproterenol; Potassium Channels; T-Lymphocytes; Temperature | 1992 |
Control of cyclic AMP levels in primary cultures of human tracheal smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Carbachol; Cells, Cultured; Colforsin; Collagenases; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Humans; Isoproterenol; Muscle, Smooth; Phosphodiesterase Inhibitors; Propanolamines; Trachea | 1992 |
Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene.
Topics: 3T3 Cells; Animals; Blotting, Northern; Colforsin; Dexamethasone; Dinoprostone; Mice; Mitogens; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Interleukin-1 beta- and forskolin-induced synthesis and secretion of group II phospholipase A2 and prostaglandin E2 in rat mesangial cells is prevented by transforming growth factor-beta 2.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Cells, Cultured; Chromatography, Affinity; Colforsin; Dinoprostone; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Glomerular Mesangium; Interleukin-1; Molecular Sequence Data; Phospholipases A; Phospholipases A2; Rats; Transforming Growth Factor beta | 1992 |
Prostaglandin E2 stimulates insulin-like growth factor I synthesis in osteoblast-enriched cultures from fetal rat bone.
Topics: Animals; Bone and Bones; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Insulin-Like Growth Factor I; Osteoblasts; Parathyroid Hormone; Radioimmunoassay; Rats; Time Factors; Transcription, Genetic | 1991 |
Actions of peptide YY and neuropeptide Y on chief cells from guinea pig stomach.
Topics: Adenylate Cyclase Toxin; Animals; Carbachol; Cholera Toxin; Colforsin; Dinoprostone; Gastric Mucosa; Gastrointestinal Hormones; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Neuropeptide Y; Pepsinogens; Peptide YY; Peptides; Pertussis Toxin; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Secretin; Sincalide; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1991 |
Cyclic AMP- and inositol phosphate-independent inhibition of Ca2+ influx by cholera toxin in CD3-stimulated Jurkat T cells. A study with a cholera toxin-resistant cell variant and the Ca2+ endoplasmic reticulum-ATPase inhibitor thapsigargin.
Topics: Antigens, Differentiation, T-Lymphocyte; Calcium; Calcium-Transporting ATPases; CD3 Complex; Cell Division; Cell Line; Cholera Toxin; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Dinoprostone; Drug Antagonism; Gene Expression Regulation; Humans; In Vitro Techniques; Inositol Phosphates; Receptors, Antigen, T-Cell; T-Lymphocytes; Terpenes; Thapsigargin | 1991 |
NF-kappa B activation by tumor necrosis factor alpha in the Jurkat T cell line is independent of protein kinase A, protein kinase C, and Ca(2+)-regulated kinases.
Topics: Calcium; Cell Line; Cholera Toxin; Clone Cells; Colforsin; Cyclic AMP; Dinoprostone; Humans; Hydrogen-Ion Concentration; Kinetics; Lymphoma; NF-kappa B; Nigericin; Oligonucleotide Probes; Protein Kinase C; Protein Kinases; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1991 |
Effects of lipolytic and antilipolytic agents on glucose transport in human fat cells.
Topics: Adenylyl Cyclase Inhibitors; Adipose Tissue; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Bucladesine; Cells, Cultured; Clonidine; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Glucose; Humans; Insulin; Lipolysis; Niacin; Phenylisopropyladenosine; Xanthines | 1991 |
Modulation by epidermal growth factor of the basal 1,25(OH)2D3 receptor level and the heterologous up-regulation of the 1,25(OH)2D3 receptor in clonal osteoblast-like cells.
Topics: Animals; Bucladesine; Calcitriol; Cell Line; Clone Cells; Colforsin; Cyclic AMP; Dinoprostone; Epidermal Growth Factor; Osteoblasts; Parathyroid Hormone; Receptors, Calcitriol; Receptors, Steroid; Up-Regulation | 1991 |
Modulation of T-cell activation through protein kinase C- or A-dependent signalling pathways synergistically increases human immunodeficiency virus long terminal repeat induction by cytomegalovirus immediate-early proteins.
Topics: Antigens, CD; CD4 Antigens; Cell Line; Colforsin; Cyclic AMP; Cytomegalovirus; Dinoprostone; HIV Long Terminal Repeat; Humans; Kinetics; Lymphocyte Activation; Promoter Regions, Genetic; Protein Kinase C; Protein Kinases; Recombinant Proteins; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha | 1991 |
Adenosine 3',5'-monophosphate in relation to inhibition of cervical smooth muscle activity in early pregnant women.
Topics: Cervix Uteri; Colforsin; Cyclic AMP; Dinoprostone; Female; Humans; Muscle, Smooth; Pregnancy; Pregnancy Trimester, First; Relaxin; Uterine Contraction | 1991 |
Modulation of the B cell response to T-independent antigens by prostaglandins: evidence for effector system cross-talk.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Alprostadil; Animals; Antibodies, Anti-Idiotypic; Antigens, T-Independent; B-Lymphocytes; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Immunoglobulin M; In Vitro Techniques; Mice; Mice, Nude; Phosphoric Diester Hydrolases; Prostaglandins E | 1991 |
Cyclic adenosine monophosphate-stimulating agents induce ecto-5'-nucleotidase activity and inhibit DNA synthesis in rat cultured mesangial cells.
Topics: 5'-Nucleotidase; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; DNA; Enzyme Induction; Glomerular Mesangium; Isoproterenol; Rats; Thymidine | 1991 |
Regulation of osteocalcin secretion by human primary bone cells and by the human osteosarcoma cell line MG-63.
Topics: Bone and Bones; Bucladesine; Calcitriol; Calcium; Colforsin; Cyclic AMP; Dexamethasone; Dinoprostone; Humans; Osteoblasts; Osteocalcin; Osteosarcoma; Parathyroid Hormone; Tumor Cells, Cultured | 1991 |
In vitro and in vivo activated T cells display increased sensitivity to PGE2.
Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; CD4 Antigens; CD8 Antigens; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Histocompatibility Antigens; Humans; Leukocyte Common Antigens; Lymphocyte Activation; Receptors, Antigen, T-Cell; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocyte Subsets; T-Lymphocytes | 1991 |
Activation of the CD3/T cell receptor (TcR) complex or of protein kinase C potentiate adenylyl cyclase stimulation in a tumoral T cell line: involvement of two distinct intracellular pathways.
Topics: Adenylyl Cyclases; Antigens, Differentiation, T-Lymphocyte; Arachidonic Acid; Calcium; CD3 Complex; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Humans; In Vitro Techniques; Inositol Phosphates; Leukemia, T-Cell; Muromonab-CD3; Protein Kinase C; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
In vitro effect of high doses of morphine on Con A induced lymphokine production.
Topics: Animals; beta-Endorphin; Cell Survival; Cells, Cultured; Clone Cells; Colforsin; Concanavalin A; Cyclic AMP; Depression, Chemical; Dinoprostone; Dose-Response Relationship, Drug; Enkephalins; Female; Lymphocyte Activation; Lymphokines; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Protein Biosynthesis; Receptors, Opioid; Spleen; T-Lymphocytes, Helper-Inducer | 1991 |
Increased cyclic AMP levels enhance IL-1 alpha and IL-1 beta mRNA expression and protein production in human myelomonocytic cell lines and monocytes.
Topics: Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Hematopoietic Stem Cells; Humans; Interleukin-1; Lipopolysaccharides; Monocytes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Antidiuretic hormone stimulation of adenylate cyclase in semicircular canal epithelium.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Calcitonin; Clonidine; Colforsin; Cyclic AMP; Dinoprostone; Endolymph; Epithelium; Glucagon; Isoproterenol; Norepinephrine; Organ Culture Techniques; Parathyroid Hormone; Rana esculenta; Semicircular Canals; Vasopressins; Vasotocin | 1991 |
Evidence that adenosine 3',5'-monophosphate mediates hormonal stimulation of prostaglandin production in cultured mouse parietal bones.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Bone and Bones; Colforsin; Cyclic AMP; Dinoprostone; Hydrocortisone; Kinetics; Mice; Organ Culture Techniques; Parathyroid Hormone | 1990 |
1,25-dihydroxyvitamin D3 and agents that increase intracellular adenosine 3',5'-monophosphate synergistically inhibit the mitogenic stimulation of human lymphocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Monophosphate; Binding Sites; Calcitriol; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Histamine; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes | 1990 |
Chloride permeability regulation via a cyclic AMP pathway in cultured human sweat duct cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic Agonists; Cell Membrane Permeability; Cells, Cultured; Chlorides; Cholera Toxin; Colforsin; Cyclic AMP; Cystic Fibrosis; Dinoprostone; Humans; Membrane Potentials; Sweat Glands | 1990 |
Role of calcium and cAMP in heterologous up-regulation of the 1,25-dihydroxyvitamin D3 receptor in an osteoblast cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenine; Adenylyl Cyclase Inhibitors; Calcitriol; Calcium; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Nitrendipine; Osteoblasts; Parathyroid Hormone; Receptors, Calcitriol; Receptors, Steroid; Up-Regulation; Verapamil | 1990 |
Cyclic AMP response to recombinant human relaxin by cultured human endometrial cells--a specific and high throughput in vitro bioassay.
Topics: 1-Methyl-3-isobutylxanthine; Biological Assay; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Endometrium; Female; Humans; Recombinant Proteins; Relaxin | 1990 |
A simple assay for agonist-regulated Cl and K conductances in salt-secreting epithelial cells.
Topics: Barium; Bumetanide; Carbachol; Cell Line; Charybdotoxin; Chloride Channels; Chlorides; Colforsin; Colonic Neoplasms; Dinoprostone; Epithelium; Humans; Iodides; Iodine Radioisotopes; Ion Channels; Ionomycin; Kinetics; Mannitol; Membrane Proteins; ortho-Aminobenzoates; Potassium Channels; Radioisotope Dilution Technique; Rubidium; Rubidium Radioisotopes; Scorpion Venoms; Sodium; Tumor Cells, Cultured | 1990 |
Biphasic action of forskolin on growth hormone and prolactin secretion by rat anterior pituitary cells in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Calcimycin; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Somatostatin; Virulence Factors, Bordetella | 1990 |
Two mechanisms of inhibition by prostaglandin E2 of hormone-dependent cell cAMP in the rat collecting tubule.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Arginine Vasopressin; Colforsin; Cyclic AMP; Dinoprostone; Indomethacin; Isoproterenol; Kidney Tubules, Collecting; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Signal Transduction; Xanthines | 1990 |
Cyclic AMP does not inhibit A23187-induced prostaglandin biosynthesis in cultured rabbit renal microvascular endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Endothelium, Vascular; Epoprostenol; Isoproterenol; Kidney Glomerulus; Microcirculation; Rabbits | 1990 |
Endothelium reduces DNA synthesis in isolated arteries.
Topics: Acetylcholine; Animals; Atrial Natriuretic Factor; Bromodeoxyuridine; Colforsin; Culture Techniques; Cyclic AMP; Cyclic GMP; Dinoprostone; DNA; Endothelium, Vascular; Iloprost; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Potassium; Rats; Rats, Inbred WKY; Renal Artery; Sympathectomy | 1991 |
Effects of cyclic AMP-affecting agents on contractile reactivity of isolated mesenteric and renal resistance arteries of the rat.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Arteries; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Mesenteric Arteries; Milrinone; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Pertussis Toxin; Pyridones; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta; Renal Circulation; Sodium Fluoride; Sympathectomy; Vascular Resistance; Vasodilator Agents; Virulence Factors, Bordetella | 1990 |
Leukotriene B4 increases intracellular calcium concentration and phosphoinositide metabolism in mouse osteoblasts via cyclic adenosine 3',5'-monophosphate-independent pathways.
Topics: 1-Methyl-3-isobutylxanthine; 1-Phosphatidylinositol 4-Kinase; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Leukotriene B4; Mice; Osteoblasts; Parathyroid Hormone; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphotransferases | 1991 |
Effects of phosphodiesterase inhibitors on vasoactive intestinal peptide-induced relaxation of isolated guinea-pig trachea.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Dinoprostone; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Papaverine; Phosphodiesterase Inhibitors; SRS-A; Trachea; Vasoactive Intestinal Peptide | 1991 |
Interaction between prostacyclin and cortisol in fetal lung cells: effects on cAMP production.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Aorta; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Epithelial Cells; Epithelium; Fibroblasts; Hydrocortisone; Iloprost; Lung; Muscle, Smooth, Vascular; Rats; RNA; Virulence Factors, Bordetella | 1991 |
Role of cyclic adenosine 3',5'-monophosphate in mediating the effect of prostaglandin E2 on decidualization in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Alkaline Phosphatase; Animals; Cell Nucleus; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Decidua; Dinoprostone; Dose-Response Relationship, Drug; Endometrium; Female; Indomethacin; Intermediate Filaments; Pregnancy; Rats; Rats, Inbred Strains | 1991 |
Modification of biological responses to interleukin-1 by agents that perturb signal transduction pathways.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Division; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Flow Cytometry; Interleukin-1; Interleukin-2; Lymphocyte Activation; Mice; Pertussis Toxin; Protein Kinase C; Recombinant Proteins; Signal Transduction; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Regulation of Na-K-2Cl cotransport in osteoblasts.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrier Proteins; Cell Line; Chlorides; Colforsin; Cyclic AMP; Dinoprostone; Egtazic Acid; Kinetics; Osteoblasts; Osteosarcoma; Ouabain; Parathyroid Hormone; Potassium; Rubidium; Second Messenger Systems; Sodium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate | 1991 |
Effects of PGE2 and a thromboxane A2 analogue on uptake of IgG complexes and LDL by mesangial cells.
Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Actins; Animals; Biological Transport; Cells, Cultured; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Glomerular Mesangium; Humans; Immunoglobulin G; Kinetics; Lipoproteins, LDL; Prostaglandin Endoperoxides, Synthetic; Rats; Thromboxane A2 | 1991 |
Further confirmation of the role of adenyl cyclase and of cAMP-dependent protein kinase in primary afferent hyperalgesia.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Dinoprostone; Epoprostenol; Hyperalgesia; Male; Phosphorylation; Protein Kinases; Pyrrolidinones; Rats; Rats, Inbred Strains; Rolipram; Second Messenger Systems; Sensory Thresholds; Thionucleotides | 1991 |
Evidence that the inhibition of TE85 human bone cell proliferation by agents which stimulate cAMP production may in part be mediated by changes in the IGF-II regulatory system.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Bone and Bones; Bucladesine; Carrier Proteins; Cell Division; Colforsin; Cyclic AMP; Dinoprostone; Humans; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor II; Molecular Sequence Data; Osteosarcoma; Tumor Cells, Cultured | 1991 |
Diabetes decreases sensitivity of adipocyte lipolysis to inhibition by Gi-linked receptor agonists.
Topics: Adipose Tissue; Animals; Cell Membrane; Colforsin; Diabetes Mellitus, Experimental; Dinoprostone; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Immunoblotting; Lipolysis; Male; Niacin; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Xanthines | 1991 |
Signal transduction pathway in gastric mucous cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Carbachol; Cell Membrane; Cholera Toxin; Colforsin; Cytosol; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Gastric Mucosa; Guinea Pigs; Histamine; In Vitro Techniques; Kinetics; Phosphatidylserines; Protein Kinase C; Protein Kinases; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines.
Topics: Animals; Clone Cells; Colforsin; Cyclic AMP; Dinoprostone; Interferon-gamma; Interleukin-2; Interleukin-4; Interleukin-5; Mice; Mice, Inbred Strains; T-Lymphocyte Subsets; T-Lymphocytes, Helper-Inducer; Time Factors | 1991 |
Cyclic AMP-elevating agents block chemoattractant activation of diradylglycerol generation by inhibiting phospholipase D activation.
Topics: Chemotactic Factors; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Enzyme Activation; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Stimulation, Chemical; Superoxides; Theophylline | 1991 |
Sensitization enhances the adenylyl cyclase responsiveness in alveolar macrophages. Changes induced at post-receptor level.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Dinoprostone; Enzyme Activation; GTP-Binding Proteins; Guinea Pigs; Iodocyanopindolol; Isoproterenol; Macrophage Activation; Macrophages; Male; Ovalbumin; Pindolol; Pulmonary Alveoli; Signal Transduction; Timolol | 1991 |
Cytokine- and forskolin-induced synthesis of group II phospholipase A2 and prostaglandin E2 in rat mesangial cells is prevented by dexamethasone.
Topics: Animals; Cells, Cultured; Colforsin; Cytokines; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glomerular Mesangium; Immunoblotting; Phospholipases A; Phospholipases A2; Radioimmunoassay; Rats | 1991 |
Synthesis of prostaglandins in cholera toxin-treated Chinese hamster ovary cells.
Topics: Alprostadil; Animals; Cell Line; Cholera Toxin; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Kinetics; Prostaglandins; Prostaglandins F; Thromboxane B2 | 1990 |
Delineation of the mechanism of inhibition of human T cell activation by PGE2.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Blotting, Northern; CD28 Antigens; CD3 Complex; CD4-Positive T-Lymphocytes; Cholera Toxin; Colforsin; Cyclic AMP; Dideoxyadenosine; Dinoprostone; Gene Expression; Humans; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Phytohemagglutinins; Receptors, Antigen, T-Cell; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Contrasting effects of PGE2 and PGD2: ion transport in the canine proximal colon.
Topics: Animals; Biological Transport; Carbachol; Colforsin; Colon; Dinoprostone; Dogs; Electric Conductivity; Epithelium; Female; Indomethacin; Intestinal Mucosa; Ions; Male; Prostaglandin D2 | 1991 |
In vitro release of gonadotropin-releasing hormone from the brain preoptic-anterior hypothalamic region and pituitary of female goldfish.
Topics: Amino Acid Sequence; Animals; Calcimycin; Colforsin; Dinoprostone; Dopamine; Female; Goldfish; Gonadotropin-Releasing Hormone; Hypothalamus, Anterior; In Vitro Techniques; Molecular Sequence Data; Norepinephrine; Pituitary Gland; Potassium; Preoptic Area; Radioimmunoassay; Serotonin; Verapamil | 1991 |
Intracellular localization of group II phospholipase A2 in rat vascular smooth muscle cells and its possible relationship to eicosanoid formation.
Topics: Animals; Blotting, Western; Cells, Cultured; Colchicine; Colforsin; Cycloheximide; Dactinomycin; Dinoprostone; Fluorescent Antibody Technique; Immunoenzyme Techniques; Male; Muscle, Smooth, Vascular; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha | 1991 |
Deficient activity of nucleotide binding regulatory protein coupled with PGE2 receptor in renal medulla of spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Colforsin; Dinoprostone; GTP-Binding Proteins; Hypertension; Kidney Medulla; Male; Prostaglandins E; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Prostaglandin; Sodium Fluoride | 1990 |
Immunocytology on microwave-fixed cells reveals rapid and agonist-specific changes in subcellular accumulation patterns for cAMP or cGMP.
Topics: Animals; Atrial Natriuretic Factor; Calcitonin; Cell Line; Cell-Free System; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Fibroblasts; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Humans; Immunoenzyme Techniques; Isoproterenol; Mice; Microwaves; Nitroprusside; Skin; Subcellular Fractions; Thiocyanates | 1990 |
Responsiveness of adenylate cyclase to PGE2 and forskolin in isolated cells from micromass cultures of chick limb mesenchyme during chondrogenesis.
Topics: Adenylyl Cyclases; Animals; Cartilage; Chick Embryo; Colforsin; Culture Techniques; Dinoprostone; Enzyme Activation; Extremities; Receptors, Prostaglandin; Receptors, Prostaglandin E | 1990 |
Vasodilatation and inhibition of mediator release represent two distinct mechanisms for prostaglandin modulation of acute mast cell-dependent inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Epoprostenol; In Vitro Techniques; Inflammation; Leukocytes; Male; Mast Cells; Mesocricetus; Microcirculation; Muscle Tonus; Muscle, Smooth, Vascular; Nitroprusside; Prostaglandins; Vasodilation | 1990 |
Modulation of interleukin-1 beta production by cyclic AMP in human monocytes.
Topics: Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Humans; Interleukin-1; Kinetics; Lipopolysaccharides; Monocytes; Tetradecanoylphorbol Acetate | 1990 |
Effects of prostacyclin on the cAMP system in cultured rat inner medullary collecting duct cells.
Topics: Animals; Arginine Vasopressin; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Drug Tolerance; Epoprostenol; Kidney Medulla; Kidney Tubules; Kidney Tubules, Collecting; Permeability; Rats; Rats, Inbred Strains; Water | 1990 |
Cyclic AMP-dependent inhibition of collagen synthesis in avian epiphyseal cartilage cells: effect of chicken and human parathyroid hormone and parathyroid hormone-related peptide.
Topics: Animals; Cells, Cultured; Chickens; Colforsin; Collagen; Cyclic AMP; Dinoprostone; Fibroblasts; Growth Plate; Humans; Neoplasm Proteins; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Protein Biosynthesis; Skin; Teriparatide | 1990 |
Failure of F-Met-Leu-Phe to induce chemotaxis in differentiated promyelocytic (HL-60) leukemia cells.
Topics: Antigens, Surface; Bucladesine; Butyrates; Cell Differentiation; Cell Division; Chemotaxis, Leukocyte; Colforsin; Dinoprostone; Humans; Hydrogen Peroxide; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Tumor Cells, Cultured | 1990 |
Growth and protein phosphorylation in the Nb2 lymphoma: effect of prolactin, cAMP, and agents that activate adenylate cyclase.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; GTP-Binding Proteins; Humans; Lymphoma, Non-Hodgkin; Neoplasm Proteins; Pertussis Toxin; Phosphorylation; Prolactin; Rats; Signal Transduction; T-Lymphocytes; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Regulation of platelet-activating factor receptor and platelet-activating factor receptor-mediated biological responses by cAMP in rat Kupffer cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Isoproterenol; Kinetics; Kupffer Cells; Phenylephrine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane B2 | 1990 |
Agents that raise cAMP in human T lymphocytes release an intracellular pool of calcium in the absence of inositol phosphate production.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcium; CD3 Complex; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Egtazic Acid; Humans; Inositol Phosphates; Kinetics; Receptors, Antigen, T-Cell; T-Lymphocytes | 1990 |
Adenylate cyclase system in fetal rat keratinizing epidermal cells (FRSK cells) and SV40-transformed human keratinocytes.
Topics: Adenosine; Adenylyl Cyclases; Animals; Blotting, Northern; Cell Line; Cell Line, Transformed; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Epinephrine; Histamine; Humans; Keratinocytes; Rats; RNA, Messenger; Simian virus 40 | 1990 |
Control of interleukin-1 beta expression by protein kinase C and cyclic adenosine monophosphate in myeloid leukemia cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Gene Expression; Humans; Interleukin-1; Isoquinolines; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Piperazines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Control of fluid transport in human rectal adenocarcinoma cells (HRA-19) in monolayer and collagen gel cultures.
Topics: Adenocarcinoma; Cholera Toxin; Colforsin; Dinoprostone; Epithelium; Extracellular Space; Humans; Indomethacin; Microscopy, Phase-Contrast; Rectal Neoplasms; Tumor Cells, Cultured | 1990 |
Transforming growth factor beta enhances parathyroid hormone stimulation of adenylate cyclase in clonal osteoblast-like cells.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Dinoprostone; Isoproterenol; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Rats; Transforming Growth Factors; Tumor Cells, Cultured | 1990 |
Chronic regulation of ovarian oxytocin and progesterone release by prostaglandins: opposite effects in bovine granulosa and early luteal cells.
Topics: Alprostadil; Animals; Cattle; Cells, Cultured; Colforsin; Corpus Luteum; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Female; Granulosa Cells; Insulin-Like Growth Factor I; Ovary; Oxytocin; Phorbol 12,13-Dibutyrate; Progesterone | 1990 |
Direct effect of parathyroid hormone on the proliferation of osteoblast-like cells; a possible involvement of cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcimycin; Cell Count; Cell Division; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; DNA; Dose-Response Relationship, Drug; Osteoblasts; Parathyroid Hormone; Prostaglandins E; Thymidine; Time Factors | 1985 |
Stimulation of cyclic adenosine 3',5'-monophosphate production enhances hypothalamic luteinizing hormone-releasing hormone release without increasing prostaglandin E2 synthesis: studies in prepubertal female rats.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Animals; Bacterial Toxins; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Median Eminence; Pertussis Toxin; Prostaglandins E; Rats; Rats, Inbred Strains; Sexual Maturation; Virulence Factors, Bordetella | 1985 |
Sodium-dependent phosphate transport inhibited by parathyroid hormone and cyclic AMP stimulation in an opossum kidney cell line.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport, Active; Bucladesine; Cattle; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; Dinoprostone; Dose-Response Relationship, Drug; Kidney; Monosaccharide Transport Proteins; Opossums; Parathyroid Hormone; Phosphates; Prostaglandins E; Sodium; Time Factors | 1986 |
1,25-Dihydroxyvitamin D3 and adenosine 3',5'-monophosphate synergistically promote differentiation of a monocytic cell line.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Calcitriol; Cell Differentiation; Cell Line; Colforsin; Complement C5; Complement C5a; Cyclic AMP; Dinoprostone; Drug Synergism; Humans; Isoproterenol; Lymphoma; Monocytes; Prostaglandins E; Receptor, Anaphylatoxin C5a; Receptors, Complement | 1986 |
Osmolality, vasopressin-stimulated cAMP, and PGE2 synthesis in rat collecting tubule cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Calcimycin; Colforsin; Cyclic AMP; Dinoprostone; Kidney Tubules; Kidney Tubules, Collecting; Osmolar Concentration; Phosphodiesterase Inhibitors; Prostaglandins E; Rats; Rats, Inbred Strains; Sodium Chloride; Stimulation, Chemical; Urea | 1986 |
Characteristics of the desensitization of growth hormone and cyclic AMP responses to growth hormone-releasing factor and prostaglandin E2 in rat anterior pituitary cells in culture.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Drug Tolerance; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Kinetics; Nifedipine; Pituitary Gland, Anterior; Prostaglandins E; Rats; Rats, Inbred Strains | 1986 |
Prostaglandin E2 stimulates DNA synthesis by a cyclic AMP-independent pathway in osteoblastic clone MC3T3-E1 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Division; Clone Cells; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Dinoprostone; DNA; Mice; Osteoblasts; Prostaglandins E | 1986 |
Parathyroid hormone stimulation of alkaline phosphatase activity in cultured neonatal mouse calvarial bone cells: involvement of cyclic AMP and calcium.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Alkaline Phosphatase; Animals; Bone and Bones; Calcimycin; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Mice; Parathyroid Hormone; Peptide Fragments; Prostaglandins E; Skull | 1986 |
Prostanoid inhibition of canine parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aminopyrine; Animals; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Dogs; Enprostil; Histamine; Parietal Cells, Gastric; Prostaglandins E; Prostaglandins E, Synthetic; Stimulation, Chemical | 1986 |
Comparative study of the effects of cyclic nucleotide phosphodiesterase inhibitors on bone resorption and cyclic AMP formation in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Bone and Bones; Bone Resorption; Calcium; Colforsin; Cyclic AMP; Dinoprostone; In Vitro Techniques; Indomethacin; Kinetics; Lysosomes; Mice; Parathyroid Hormone; Prostaglandins E; Pyrrolidinones; Rolipram; Theophylline | 1986 |
Copper amplification of prostaglandin E2 stimulation of the release of luteinizing hormone-releasing hormone is a postreceptor event.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Copper; Dinoprostone; Drug Synergism; Gonadotropin-Releasing Hormone; Histidine; Male; Median Eminence; Organ Culture Techniques; Prostaglandins E; Rats; Receptors, LHRH | 1987 |
Differential effects of prostaglandins and isoproterenol on cAMP content and Na, K pump activity in rat submandibular acini.
Topics: Alprostadil; Animals; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Ion Channels; Isoproterenol; Male; Ouabain; Potassium; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains; Rubidium Radioisotopes; Sodium; Submandibular Gland | 1987 |
Effects of TMB-8, a calcium antagonist, on transport properties of the isolated canine tracheal epithelium.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biological Transport; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Chlorides; Colforsin; Dinoprost; Dinoprostone; Dogs; Epithelium; Gallic Acid; Phenobarbital; Prostaglandins E; Prostaglandins F; Sodium; Trachea | 1987 |
Apical membrane chloride channels in a colonic cell line activated by secretory agonists.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cell Line; Cell Membrane; Chlorides; Colforsin; Cyclic AMP; Dinoprostone; Evoked Potentials; Ion Channels; Kinetics; Prostaglandins E | 1988 |
Phorbol esters modulate cyclic AMP accumulation in porcine thyroid cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1988 |
The effect of parathyroid hormone and atrial natriuretic peptide on cyclic nucleotides production and proliferation of avian epiphyseal growth plate chondroprogenitor cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenocorticotropic Hormone; Animals; Atrial Natriuretic Factor; Cartilage; Cells, Cultured; Chick Embryo; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Growth Plate; Kinetics; Parathyroid Hormone; Peptide Fragments; Prostaglandins E | 1988 |
Biophysical properties of a chloride channel in the apical membrane of a secretory epithelial cell.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Chloride Channels; Chlorides; Colforsin; Colonic Neoplasms; Dinoprostone; Epithelium; Intestinal Secretions; Ion Channels; Membrane Potentials; Membrane Proteins; Tumor Cells, Cultured | 1988 |
Electrophysiological correlates of fluid transport in cultured porcine thyroid cells.
Topics: Action Potentials; Amiloride; Animals; Biological Transport; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Epithelium; Ion Channels; Ouabain; Swine; Thyroid Gland; Water | 1988 |
Beta-adrenergic and prostanoid inhibition of canine fundic mucosal mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Animals; Calcimycin; Colforsin; Concanavalin A; Cyclic AMP; Dinoprostone; Dogs; Enprostil; Epinephrine; Gastric Fundus; Gastric Mucosa; Histamine Release; Isoproterenol; Liver; Mast Cells; Propanolamines; Propranolol; Prostaglandins E, Synthetic; Tetradecanoylphorbol Acetate | 1989 |
Insulin enhances luteinizing hormone-stimulated steroidogenesis by porcine theca cells.
Topics: 1-Methyl-3-isobutylxanthine; Androstenedione; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Female; Hydroxycholesterols; Insulin; Insulin-Like Growth Factor I; Kinetics; Luteinizing Hormone; Pregnenolone; Progesterone; Relaxin; Swine; Theca Cells | 1989 |
Secretagogues increase apical membrane conductance of isolated bullfrog corneal epithelium pretreated with loop diuretics.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Bumetanide; Chlorides; Colforsin; Cornea; Dinoprostone; Diuretics; Epithelium; Furosemide; In Vitro Techniques; Membrane Potentials; Rana catesbeiana | 1989 |
Ca2+-dependent and -independent secretagogue action on gastric mucus secretion in rabbit mucosal explants.
Topics: Acetylcholine; Acetylglucosamine; Animals; Atropine; Calcimycin; Calcium; Calmodulin; Colforsin; Dinoprostone; Gastric Fundus; Gastric Mucosa; Glycoproteins; Histamine; Male; Molecular Weight; Organ Culture Techniques; Pentagastrin; Pyloric Antrum; Rabbits; Sulfonamides; Tetradecanoylphorbol Acetate | 1989 |
Prostaglandin E2-dependent induction of granulocyte-macrophage colony-stimulating factor secretion by cloned murine helper T cells.
Topics: Alprostadil; Animals; Cholera Toxin; Clone Cells; Colforsin; Colony-Stimulating Factors; Dinoprost; Dinoprostone; Drug Synergism; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Interleukin-2; Kinetics; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; T-Lymphocytes, Helper-Inducer | 1989 |
Prostaglandin E2 and F2 alpha inhibit growth of human gastric carcinoma cell line KATO III with simultaneous stimulation of cyclic AMP production.
Topics: Bucladesine; Carcinoma; Cell Division; Colforsin; Cyclic AMP; Depression, Chemical; Dinoprost; Dinoprostone; Humans; Inositol Phosphates; Stomach Neoplasms; Tumor Cells, Cultured | 1989 |
Prostaglandin E receptors in bovine adrenal medulla are coupled to adenylate cyclase via Gi and to phosphoinositide metabolism in a pertussis toxin-insensitive manner.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenal Medulla; Animals; Bucladesine; Catecholamines; Cattle; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; GTP-Binding Proteins; Nicotine; Pertussis Toxin; Phosphatidylinositols; Receptors, Prostaglandin; Receptors, Prostaglandin E; Type C Phospholipases; Virulence Factors, Bordetella | 1989 |
Dual effects of protein kinase-C on receptor-stimulated cAMP accumulation in a human T-cell leukemia line.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Blotting, Western; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Humans; Leukemia, T-Cell; Phorbol Esters; Phosphorylation; Protein Kinase C; Receptors, Prostaglandin; Receptors, Purinergic | 1989 |
Modulation of T cell activation by differential regulation of the phosphorylation of two cytosolic proteins. Implication of both Ca2+ and cyclic AMP-dependent protein kinases.
Topics: Antigens, Differentiation, T-Lymphocyte; Calcium; CD3 Complex; Cell Line; Colforsin; Cyclic AMP; Cytosol; Dinoprostone; Humans; Interleukin-2; Lymphocyte Activation; Phosphoproteins; Phosphorylation; Protein Kinases; Receptors, Antigen, T-Cell; T-Lymphocytes | 1989 |
Action of calcitonin gene-related peptide on rat aortic smooth muscle.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Aorta, Thoracic; Arginine Vasopressin; Calcitonin Gene-Related Peptide; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; In Vitro Techniques; Muscle, Smooth, Vascular; Rats | 1989 |
Multiple signaling pathways of histamine H2 receptors. Identification of an H2 receptor-dependent Ca2+ mobilization pathway in human HL-60 promyelocytic leukemia cells.
Topics: Calcium; Calcium Channel Blockers; Cell Differentiation; Cholera Toxin; Colforsin; Cyclic AMP; Dimethyl Sulfoxide; Dinoprostone; Histamine; Humans; Inositol 1,4,5-Trisphosphate; Isoproterenol; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Histamine H2; Signal Transduction; Tumor Cells, Cultured | 1989 |
Modulation of responsiveness of the adenylate cyclase system in avian chondroprogenitor cells by pertussis toxin, PTH, and PGE2.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Membrane; Cells, Cultured; Chickens; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Growth Plate; Immunoblotting; Parathyroid Hormone; Pertussis Toxin; Stem Cells; Virulence Factors, Bordetella | 1989 |
Differential sensitivity to cAMP among human cord and maternal/adult peripheral lymphocytes discloses differences between PHA- and OKT3-induced activation pathways.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Antibodies, Monoclonal; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Female; Fetal Blood; Humans; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins | 1989 |
Effects of defolliculation on membrane current responses of Xenopus oocytes.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cell Separation; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Dopamine; Female; In Vitro Techniques; Membrane Potentials; Microbial Collagenase; Norepinephrine; Oocytes; Ovarian Follicle; Potassium Channels; Vasoactive Intestinal Peptide; Xenopus laevis | 1989 |
Interferon-gamma down-regulates membrane adenylate cyclase activity of a murine macrophage-like cell line (P388D1).
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Animals; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; Dinoprostone; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; Interferon-gamma; Macrophages; Mice; Recombinant Proteins; Signal Transduction; Sodium Fluoride | 1989 |
Effect of phosphodiesterase inhibitors on bradykinin-mediated prostaglandin E2 and cyclic AMP synthesis in renal papillary collecting tubule cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bradykinin; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; In Vitro Techniques; Kidney Medulla; Kidney Tubules; Kidney Tubules, Collecting; Male; Phosphodiesterase Inhibitors; Prostaglandins E; Rabbits | 1985 |
Uncoupling of excitation from contraction in uterine smooth muscle in near-term ewes.
Topics: Animals; Colforsin; Dinoprostone; Electromyography; Female; Muscle, Smooth; Pharmaceutical Vehicles; Pregnancy; Uterine Contraction; Uterus | 1989 |
Benzyl alcohol increases membrane fluidity and modulates cyclic AMP synthesis in intact renal epithelial cells.
Topics: Animals; Benzyl Alcohol; Benzyl Alcohols; Benzyl Compounds; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Diphenylhexatriene; Epithelium; Fluorescence Polarization; Fluorescent Dyes; Glucagon; GTP-Binding Proteins; Indomethacin; Kidney; Manganese; Membrane Fluidity; Prostaglandins E; Vasopressins | 1987 |
Adenylate cyclase in the primate corpus luteum during chorionic gonadotropin treatment simulating early pregnancy: homologous versus heterologous desensitization.
Topics: Adenylyl Cyclases; Animals; Chorionic Gonadotropin; Colforsin; Corpus Luteum; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Female; Guanylyl Imidodiphosphate; Isoproterenol; Macaca mulatta; Pregnancy; Pregnancy, Animal; Progesterone; Prostaglandins E; Receptors, LH | 1988 |
Cyclic AMP concentrations modulate both calcium flux and hydrolysis of phosphatidylinositol phosphates in mouse T lymphocytes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Calcium; Calcium Channel Blockers; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Hydrolysis; Kinetics; Male; Mice; Mice, Inbred Strains; Phosphatidylinositols; Phosphorylation; Prostaglandins E; T-Lymphocytes | 1988 |
Tissue and species specific responsiveness of developing avian and murine secondary palates to prostaglandin E2 stimulation.
Topics: Animals; Cell Differentiation; Chick Embryo; Colforsin; Cyclic AMP; Dinoprostone; Epithelial Cells; Epithelium; Female; Isoproterenol; Mice; Mice, Inbred C57BL; Palate; Prostaglandins E; Species Specificity | 1988 |
Estrogen reduces beta-adrenoceptor-mediated cAMP production and the concentration of the guanyl nucleotide-regulatory protein, Gs, in rabbit myometrium.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Estrogens; Female; GTP-Binding Proteins; Isoproterenol; Myometrium; Ovariectomy; Progesterone; Prostaglandins E; Rabbits; Receptors, Adrenergic, beta | 1988 |
Effect of phorbol esters on the hormonal responsiveness of isolated white fat cells.
Topics: Adipose Tissue; Animals; Colforsin; Cyclic AMP; Dinoprostone; Epinephrine; Fatty Acids; In Vitro Techniques; Isoproterenol; Lipolysis; Male; Phenylisopropyladenosine; Phospholipids; Prostaglandins E; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Effect of Na-K adenosinetriphosphatase activity on relaxation of canine tracheal smooth muscle.
Topics: Animals; Calcium Channel Blockers; Colforsin; Dinoprostone; Dogs; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Potassium; Prostaglandins E; Sodium-Potassium-Exchanging ATPase; Trachea | 1988 |
Activation of protein kinase C attenuates prostaglandin E2 responses in a colonic cell line.
Topics: Animals; Bucladesine; Cell Line; Cells, Cultured; Colforsin; Colon; Cyclic AMP; Dimethyl Sulfoxide; Dinoprostone; Enzyme Activation; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Protein Kinase C | 1988 |
Forskolin inhibition of glucose transport in bone cell cultures through a cAMP-independent mechanism.
Topics: Animals; Benzyl Alcohol; Benzyl Alcohols; Biological Transport; Bone and Bones; Cell Line; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Deoxyglucose; Dinoprostone; Glucose; Humans; Isoproterenol; Parathyroid Hormone; Prostaglandins E | 1988 |
Parathyroid hormone and prostaglandin E2 stimulate both inositol phosphates and cyclic AMP accumulation in mouse osteoblast cultures.
Topics: Animals; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Indomethacin; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mice; Osteoblasts; Parathyroid Hormone; Prostaglandins E; Stimulation, Chemical; Sugar Phosphates | 1988 |
IFN-gamma and prostaglandin E2 inhibit IL-4-induced expression of Fc epsilon R2/CD23 on B lymphocytes through different mechanisms without altering binding of IL-4 to its receptor.
Topics: Adenosine Monophosphate; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Binding, Competitive; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Humans; Immunoglobulin E; Interferon-gamma; Interleukin-4; Interleukins; Intracellular Fluid; Iodine Radioisotopes; Receptors, Fc; Receptors, IgE; Receptors, Interleukin-4; Receptors, Mitogen | 1988 |
Role of adenosine 3'5'-cyclic monophosphate in antineoplastic effect of prostaglandins (PGE1, PGE2, PGD2 and PGA1) on human neuroblastoma cells.
Topics: Alprostadil; Cell Survival; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Neuroblastoma; Prostaglandin D2; Prostaglandins; Prostaglandins A; Tumor Cells, Cultured | 1988 |
Possible induction of fatty acid cyclooxygenase in mouse osteoblastic cells (MC3T3-E1) by cAMP.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Cholera Toxin; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Induction; Epinephrine; Immunosorbent Techniques; Isoproterenol; Mice; Norepinephrine; Osteoblasts; Phenylephrine; Propranolol; Prostaglandin-Endoperoxide Synthases; Receptors, Adrenergic, beta | 1988 |
PGE2-induced cyclic AMP accumulation in human CD4+ T cells is strongly enhanced during the CD2-mediated activatory process.
Topics: Antibodies, Monoclonal; Calcimycin; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Humans; Isoproterenol; Lymphocyte Activation; Protein Kinase C; Receptors, Antigen, T-Cell; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1988 |
Effect of pertussis toxin on parathyroid hormone-stimulated cyclic AMP production in cultured kidney cells.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dexamethasone; Dinoprostone; GTP-Binding Proteins; Kidney; Opossums; Parathyroid Hormone; Pertussis Toxin; Stimulation, Chemical; Virulence Factors, Bordetella | 1988 |
Phorbol esters enhance neurotransmitter-stimulated cyclic AMP production in rat brain slices.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Isoproterenol; Male; Molecular Weight; Neurotransmitter Agents; Phorbol Esters; Phosphorylation; Prostaglandins E; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Tissue Distribution; Vasoactive Intestinal Peptide | 1986 |
Evidence that PGE2 stimulates intestinal epithelial cell adenylate cyclase by a receptor-mediated mechanism.
Topics: Adenylyl Cyclases; Animals; Colforsin; Dinoprostone; Enzyme Activation; Fluorides; Guanosine Triphosphate; In Vitro Techniques; Intestinal Mucosa; Polidocanol; Polyethylene Glycols; Prostaglandins E; Rats; Receptors, Prostaglandin; Receptors, Prostaglandin E; Stimulation, Chemical | 1987 |
Hormone-sensitive adenylate cyclase of prolactin-producing rat pituitary adenoma (GH4C1) cells: molecular organization.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Dinoprostone; Hormones; Isoproterenol; Kinetics; Pituitary Neoplasms; Prolactinoma; Somatostatin; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 1988 |
Interleukin 1 stimulates its own receptor expression on human fibroblasts through the endogenous production of prostaglandin(s).
Topics: Adenosine Monophosphate; Colforsin; Dinoprostone; Fibroblasts; Glucocorticoids; Humans; Interleukin-1; Prostaglandins; Protein Synthesis Inhibitors; Receptors, Immunologic; Receptors, Interleukin-1 | 1988 |
Induction of osteoblastic cell differentiation by forskolin. Stimulation of cyclic AMP production and alkaline phosphatase activity.
Topics: Alkaline Phosphatase; Animals; Bucladesine; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; Drug Interactions; Kinetics; Mice; Mice, Inbred C57BL; Osteoblasts; Prostaglandins E | 1985 |
Effects of prostaglandin E2 and cholera toxin on apical sodium uptake in thyroid epithelial cells: role of cAMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amiloride; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; Dose-Response Relationship, Drug; Epithelium; Prostaglandins E; Sodium; Swine; Thyroid Gland; Time Factors | 1985 |
Inhibitory effect of methacholine on drug-induced relaxation, cyclic AMP accumulation, and cyclic AMP-dependent protein kinase activation in canine tracheal smooth muscle.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; Dogs; Enzyme Activation; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Muscle Relaxation; Muscle, Smooth; Prostaglandins E; Protein Kinases; Trachea | 1985 |
Role of prostaglandins in hypoxia-stimulated erythropoietin production.
Topics: Adenylyl Cyclases; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Diterpenes; Enzyme Activation; Erythropoietin; Glomerular Mesangium; Indomethacin; Male; Oxygen; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains | 1985 |
Calmodulin regulation of cellular cyclic AMP production in response to arginine vasopressin, prostaglandin E2 and forskolin in rat renal papillary collecting tubule cells in culture.
Topics: Animals; Arginine Vasopressin; Calcium; Calmodulin; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Kidney Medulla; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Stimulation, Chemical; Sulfonamides; Trifluoperazine | 1985 |
[Evidence for a role of calmodulin in cellular cAMP production in response to vasopressin, prostaglandin E2 and forskolin in cultured rat renal papillary collecting tubule cells].
Topics: Animals; Calmodulin; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Kidney Tubules; Kidney Tubules, Collecting; Prostaglandins E; Rats; Rats, Inbred Strains; Vasopressins | 1985 |
Inhibitory effect of prostaglandin E2, forskolin, and dibutyryl cAMP on arachidonic acid release and inositol phospholipid metabolism in guinea pig neutrophils.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Bucladesine; Calcimycin; Catechols; Colforsin; Dinoprostone; Fatty Acids, Nonesterified; Guinea Pigs; Lysosomes; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositols; Prostaglandins E; Pyrazoles; Superoxides | 1986 |
Regulation of inositol phospholipid metabolism and arachidonic acid release: inhibitory mechanism of arachidonic acid release by prostaglandin E2 and cAMP.
Topics: Animals; Arachidonic Acids; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Humans; Neutrophils; Phosphatidylinositols; Prostaglandins E | 1985 |
Relationships between the GTP content and the TSH-stimulated adenylate cyclase activity of cultured thyroid cells.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Bucladesine; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Guanosine Triphosphate; Prostaglandins E; Swine; Thyroid Gland; Thyrotropin; Time Factors | 1986 |
Prostaglandin E2 inhibition of secretagogue-stimulated [14C]aminopyrine accumulation in rat parietal cells: a model for its mechanism of action.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Aminopyrine; Animals; Bucladesine; Carbon Radioisotopes; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; GTP-Binding Proteins; Histamine; In Vitro Techniques; Isoproterenol; Male; Models, Biological; Parasympathetic Nervous System; Parietal Cells, Gastric; Pertussis Toxin; Prostaglandins E; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1986 |
Effect of adenosine receptor agonists and other compounds on cyclic AMP accumulation in forskolin-treated hippocampal slices.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Hippocampus; Histamine; Isoproterenol; Male; Phenylisopropyladenosine; Prostaglandins E; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Xanthines | 1986 |
Hydrosmotic response to vasopressin in frog skin. Control by endogenous factors.
Topics: Animals; Body Water; Calcimycin; Calcium; Colforsin; Cyclic AMP; Dinoprostone; In Vitro Techniques; Osmosis; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rana esculenta; Skin; Theophylline; Vasopressins | 1985 |
Activation of two different but complementary biochemical pathways stimulates release of hypothalamic luteinizing hormone-releasing hormone.
Topics: Animals; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Diglycerides; Dinoprostone; Drug Interactions; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Indomethacin; Norepinephrine; Prostaglandins E; Protein Kinase C; Rats; Secretory Rate; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1986 |
Calcium, calmodulin, and cyclic adenosine monophosphate modulate prostaglandin E2 release from isolated human gastric mucosal cells.
Topics: Bucladesine; Calcimycin; Calcium; Calmodulin; Carbenoxolone; Colforsin; Cyclic AMP; Dinoprostone; Gastric Mucosa; Humans; Indomethacin; Prostaglandins E; Sulfonamides; Trifluoperazine | 1986 |
Prostaglandin E2 and cyclic AMP response to vasopressin in renal medullary tubular cells.
Topics: Animals; Arginine Vasopressin; Calcimycin; Calcium; Colforsin; Cyclic AMP; Deamino Arginine Vasopressin; Dinoprostone; Female; Kidney Medulla; Kidney Tubules; Nifedipine; Prostaglandins E; Rats; Rats, Inbred Strains; Vasopressins | 1986 |
Evidence that interleukin-1 induction of synovial cell plasminogen activator is mediated via prostaglandin E2 and cAMP.
Topics: Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Humans; Indomethacin; Interleukin-1; Microbial Collagenase; Plasminogen Activators; Prostaglandins E; Synovial Membrane; Theophylline | 1986 |
A re-evaluated role for cyclic AMP in uterine relaxation. Differential effect of isoproterenol and forskolin.
Topics: Animals; Bucladesine; Carbachol; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Female; Isoproterenol; Kinetics; Myometrium; Prostaglandins E; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Uterine Contraction | 1986 |
Hormonal regulation of proton secretion in rabbit medullary collecting duct.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenalectomy; Animals; Arachidonic Acid; Arachidonic Acids; Calorimetry; Colforsin; Dinoprostone; Female; In Vitro Techniques; Indomethacin; Kallidin; Kidney Medulla; Kidney Tubules; Kinetics; Perfusion; Prostaglandins E; Protons; Rabbits | 1986 |
Antibody binding to CD5 (Tp67) and Tp44 T cell surface molecules: effects on cyclic nucleotides, cytoplasmic free calcium, and cAMP-mediated suppression.
Topics: Antibodies, Monoclonal; Antigen-Antibody Reactions; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Bucladesine; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Humans; Interleukin-1; Lymphocyte Activation; Membrane Proteins; Monocytes; Nucleotides, Cyclic; Prostaglandins E; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1986 |
Effects of prostaglandin E2, forskolin and cholera toxin on cAMP production and in vitro LH-RH release from the rat hypothalamus.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Estradiol; Female; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Ovariectomy; Perfusion; Prostaglandins E; Rats | 1986 |
Suppression of prostaglandin synthesis by analogues of cyclic AMP and forskolin in chondrocyte monolayer cultures.
Topics: Animals; Cartilage, Articular; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Feedback; Prostaglandins E; Rabbits | 1986 |
Inhibition of human B cell responsiveness by prostaglandin E2.
Topics: B-Lymphocytes; Cell Cycle; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Depression, Chemical; Dinoprost; Dinoprostone; Ethers; Humans; Ionomycin; Lymphocyte Activation; Lymphokines; Prostaglandins E; Prostaglandins F; Tetradecanoylphorbol Acetate; Vinblastine | 1987 |
Control of cyclic adenosine 3',5'-monophosphate production in osteoclasts: calcitonin-induced persistent activation and homologous desensitization of adenylate cyclase.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Calcitonin; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Kinetics; Osteoclasts; Pertussis Toxin; Prostaglandins E; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1987 |
In vitro effect of prostaglandins on the accumulation of cyclic AMP in the avian oviduct.
Topics: Animals; Birds; Chickens; Colforsin; Coturnix; Cyclic AMP; Dinoprost; Dinoprostone; Female; In Vitro Techniques; Oviducts; Prostaglandins E; Prostaglandins F; Species Specificity | 1987 |
Similarities in cAMP responses between murine lymphoid cell lines and subsets of mouse lymphocytes.
Topics: Animals; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Enzyme Activation; Histamine; Isoproterenol; Lymphocytes; Mice; Prostaglandins E; Protein Kinases | 1987 |
Protein kinase C activators and bradykinin selectively inhibit vasopressin-stimulated cAMP synthesis in MDCK cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bradykinin; Cell Line; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Enzyme Activation; Glucagon; Isoquinolines; Piperazines; Prostaglandins E; Protein Kinase C; Tetradecanoylphorbol Acetate; Vasopressins | 1987 |
Heterologous regulations of cAMP responses in pregnant rat myometrium. Evolution from a stimulatory to an inhibitory prostaglandin E2 and prostacyclin effect.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Aspirin; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Epoprostenol; Estradiol; Female; Gestational Age; GTP-Binding Proteins; Isoproterenol; Myometrium; Pertussis Toxin; Pregnancy; Pregnancy, Animal; Prostaglandins E; Rats; Virulence Factors, Bordetella | 1987 |
Inhibition of receptor-mediated stimulation of cyclic AMP accumulation in neuroblastoma-hybrid NCB-20 cells by a phorbol ester.
Topics: Adenylyl Cyclases; Animals; Cell Line; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Dopamine; GTP-Binding Proteins; Hybrid Cells; Mice; Neuroblastoma; Phosphorylation; Prostaglandins E; Protein Kinase C; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1987 |
Oxytocin activates the inositol-phospholipid-protein kinase-C system and stimulates prostaglandin production in human amnion cells.
Topics: Amnion; Calcium; Cells, Cultured; Colforsin; Dinoprostone; Egtazic Acid; Epithelium; Humans; Inositol Phosphates; Isoproterenol; Oxytocin; Prostaglandins E; Protein Kinase C; Reference Values; Ritodrine; Sugar Phosphates; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
Granulosa cell steroidogenesis and follicular fluid steroid concentrations after the onset of oestrus in cows.
Topics: Animals; Cattle; Cells, Cultured; Colforsin; Diglycerides; Dinoprostone; Estradiol; Estrone; Estrus; Female; Granulosa Cells; Luteinizing Hormone; Ovarian Follicle; Progesterone; Stimulation, Chemical; Testosterone | 1988 |
Interleukin-1 inhibits Leydig cell steroidogenesis in primary culture.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Dinoprostone; Indomethacin; Interleukin-1; Kinetics; Leydig Cells; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Receptors, LH; Testosterone | 1988 |
PGE2, forskolin, and cholera toxin interactions in rabbit cortical collecting tubule.
Topics: Animals; Body Water; Cholera Toxin; Colforsin; Dinoprostone; Drug Interactions; Female; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Kidney Tubules, Collecting; Permeability; Prostaglandins E; Rabbits; Temperature; Vasopressins | 1986 |
NaCl transport stimulates prostaglandin release in cultured renal epithelial (MDCK) cells.
Topics: Adenylyl Cyclases; Animals; Biological Transport; Cell Line; Colforsin; Dinoprostone; Dogs; Epinephrine; Epithelium; Furosemide; Isoproterenol; Kidney; Kinetics; Ouabain; Prostaglandins; Prostaglandins E; Sodium Chloride | 1986 |
Electrogenic anion secretion in cultured rat epididymal epithelium.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Animals; Anions; Biological Transport, Active; Cells, Cultured; Colforsin; Dinoprostone; Diuretics; Epididymis; Epithelium; Kallidin; Male; Prostaglandins E; Rats; Rats, Inbred Strains | 1986 |
Forskolin inhibits insulin-stimulated glucose transport in rat adipose cells by a direct interaction with the glucose transporter.
Topics: Adipose Tissue; Animals; Binding Sites; Binding, Competitive; Cell Membrane; Colforsin; Cytochalasin B; Dinoprostone; Glucose; Insulin Antagonists; Kinetics; Lipid Mobilization; Monosaccharide Transport Proteins; Prostaglandins E; Rats | 1987 |
Gold(III) inhibits activated human osteosarcoma adenylate cyclase by an action at or near the catalytic component.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Cell Line; Cell Membrane; Colforsin; Deoxyadenosines; Dideoxyadenosine; Dinoprostone; Gold; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Kinetics; Osteosarcoma; Prostaglandins E | 1987 |
Kinin effects on electrogenic ion transport in primary cultures of pig renal papillary collecting tubule cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antihypertensive Agents; Arginine Vasopressin; Biological Transport; Cells, Cultured; Chlorides; Colforsin; Dinoprostone; Diterpenes; Electric Conductivity; Epithelium; Ions; Kallidin; Kidney Tubules; Norepinephrine; Prostaglandins E; Swine | 1985 |
Effect of forskolin on prostaglandin productions in isolated dog renal arteries.
Topics: 6-Ketoprostaglandin F1 alpha; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Colforsin; Dinoprostone; Dogs; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Prostaglandins; Prostaglandins E; Renal Artery | 1985 |
Modulation of synaptic transmission in mammalian sympathetic ganglia: effects of catecholamines, prostaglandins and cyclic nucleotides.
Topics: Animals; Catecholamines; Clonidine; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; Enkephalin, Methionine; Ganglia, Sympathetic; Guinea Pigs; Kinetics; Phenylephrine; Prostaglandins E; Synaptic Transmission | 1984 |
PGE2, forskolin, and cholera toxin interactions in modulating NaCl transport in mouse mTALH.
Topics: Adenylyl Cyclases; Animals; Chlorides; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; Drug Interactions; Ion Channels; Kidney Tubules; Loop of Henle; Male; Mice; Prostaglandins E; Sodium Chloride; Stimulation, Chemical; Vasopressins | 1984 |
Somatocrinin (growth hormone releasing factor) in vitro bioactivity; Ca++ involvement, cAMP mediated action and additivity of effect with PGE2.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antihypertensive Agents; Calcium; Cholera Toxin; Cobalt; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; Growth Hormone; Growth Hormone-Releasing Hormone; Hypothalamus; Kinetics; Peptide Fragments; Pituitary Gland; Prostaglandins E; Radioimmunoassay; Rats; Somatostatin | 1982 |
Independent effects of bradykinin on adenosine 3',5'-monophosphate and prostaglandin E2 metabolism by rabbit renal medulla.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antihypertensive Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Bradykinin; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; In Vitro Techniques; Kidney Medulla; Kinetics; Prostaglandins E; Rabbits | 1984 |
Regulation of thromboplastin synthesis in mouse placental cells in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Depression, Chemical; Dinoprostone; Diterpenes; Epinephrine; Female; In Vitro Techniques; Mice; Placenta; Pregnancy; Prostaglandins E; Stimulation, Chemical; Thromboplastin | 1983 |
Effects of selected bronchodilators on antigen- and A23187-induced contraction of guinea-pig trachea.
Topics: Aminophylline; Animals; Anti-Bacterial Agents; Antigens; Bronchodilator Agents; Bucladesine; Calcimycin; Colforsin; Dinoprostone; Diterpenes; Guinea Pigs; Indomethacin; Isoproterenol; Male; Muscle Contraction; Ovalbumin; Prostaglandins E; Trachea | 1983 |
Induction of granulosa cell differentiation by forskolin: stimulation of adenosine 3',5'-monophosphate production, progesterone synthesis, and luteinizing hormone receptor expression.
Topics: Animals; Antihypertensive Agents; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Diethylstilbestrol; Dinoprostone; Diterpenes; Female; Follicle Stimulating Hormone; Granulosa Cells; Luteinizing Hormone; Progesterone; Prostaglandins E; Rats; Receptors, Cell Surface; Receptors, LH | 1984 |
Bronchodilator-mediated relaxation of normal and ovalbumin-sensitized guinea-pig airways: lack of correlation with lung adenylate cyclase activation.
Topics: Adenylyl Cyclases; Animals; Bronchodilator Agents; Colforsin; Cyclooxygenase Inhibitors; Dinoprostone; Diterpenes; Enzyme Activation; Guinea Pigs; In Vitro Techniques; Indomethacin; Isoproterenol; Lung; Male; Muscle Relaxation; Ovalbumin; Prostaglandins E; Trachea; Vasoactive Intestinal Peptide | 1984 |
Suppression of lipopolysaccharide-induced tumor necrosis factor-alpha generation from human peripheral blood monocytes by inhibitors of phosphodiesterase 4: interaction with stimulants of adenylyl cyclase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Albuterol; Amino Acid Sequence; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; Drug Interactions; Flurbiprofen; Humans; Isoenzymes; Leukocytes, Mononuclear; Lipopolysaccharides; Molecular Sequence Data; Nitroprusside; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrrolidinones; Rolipram; Stimulation, Chemical; Time Factors; Tumor Necrosis Factor-alpha | 1995 |
PGE2 induces the transition from non-adherent to adherent bone marrow mesenchymal precursor cells via a cAMP/EP2-mediated mechanism.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bone Marrow; Bone Marrow Cells; Bucladesine; Cell Adhesion; Cells, Cultured; Colforsin; Colony-Forming Units Assay; Cyclic AMP; Dexamethasone; Dinoprostone; Female; Hematopoietic Stem Cells; Kinetics; Phosphodiesterase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Receptors, Prostaglandin E; Tetradecanoylphorbol Acetate | 1995 |
Inhibition of MAP kinase by prostaglandin E2 and forskolin in rat renal mesangial cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Glomerular Mesangium; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1995 |
Interleukin-1 beta independently stimulates production of prostaglandin E2 and cyclic AMP from human decidual cells.
Topics: 1-Methyl-3-isobutylxanthine; Cells, Cultured; Colforsin; Cyclic AMP; Decidua; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Interleukin-1 | 1995 |
Adenylyl cyclase activity in human decidua and myometrium during pregnancy and labour.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Colforsin; Decidua; Dinoprost; Dinoprostone; Epinephrine; Female; Humans; In Vitro Techniques; Isoproterenol; Labor, Obstetric; Middle Aged; Myometrium; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Third; Sodium Fluoride; Stimulation, Chemical; Uterus | 1995 |
Expression of hepatocyte growth factor is up-regulated through activation of a cAMP-mediated pathway.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dexamethasone; Dinoprostone; Female; Fibroblasts; Gene Expression; Hepatocyte Growth Factor; Humans; Infant; Kinetics; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1994 |
Effects of glucocorticoid on signalling by prostaglandin E2 in osteoblast-like cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Bone Resorption; Cell Line; Colforsin; Cyclic AMP; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; GTP-Binding Proteins; Inositol Phosphates; Mice; Osteoblasts; Phosphatidylinositols; Signal Transduction; Sodium Fluoride | 1993 |
Antiproliferative effect of prostaglandin E2 in cultured guinea pig tracheal smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blood Physiological Phenomena; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Guinea Pigs; Male; Muscle, Smooth; Tetradecanoylphorbol Acetate; Trachea | 1994 |
Opioid inhibition of Ih via adenylyl cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cations; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Electric Conductivity; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ion Channels; Neurons; Nodose Ganglion | 1994 |
PGE2 induces c-fos expression by a cAMP-independent mechanism in glomerular mesangial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arachidonic Acid; Base Sequence; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression; Genes, fos; Genes, jun; Glomerular Mesangium; Male; Molecular Sequence Data; Mutagenesis; Oligodeoxyribonucleotides; Phosphoproteins; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Regulatory Sequences, Nucleic Acid; RNA, Messenger; TATA Box; Transcription Factor AP-1; Tyrosine | 1994 |
Transcriptional regulation of plasminogen activator inhibitor-1 expression in human synovial fibroblasts by prostaglandin E2: mediation by protein kinase A and role of interleukin-1.
Topics: 1-Methyl-3-isobutylxanthine; Blood; Cadaver; Cells, Cultured; Colforsin; Culture Media; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1; Plasminogen Activator Inhibitor 1; Protein Kinase Inhibitors; RNA, Messenger; Synovial Membrane; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Cross-talk between cyclooxygenase and nitric oxide pathways: prostaglandin E2 negatively modulates induction of nitric oxide synthase by interleukin 1.
Topics: Amino Acid Oxidoreductases; Animals; Base Sequence; Cells, Cultured; Colforsin; Cycloheximide; Dactinomycin; Dinoprostone; DNA Primers; DNA Probes; Enzyme Induction; Gene Expression; Glomerular Mesangium; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Indomethacin; Interleukin-1; Kinetics; Male; Models, Biological; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 1994 |
Granulocyte-macrophage colony-stimulating factor expression by human fibroblasts is both upregulated and subsequently downregulated by interleukin-1.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; Dinoprostone; Fibroblasts; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indomethacin; Interleukin-1; Lung; RNA, Messenger | 1995 |
Effects of mutations in cAMP-dependent protein kinase on chloride efflux in Caco-2 human colonic carcinoma cells.
Topics: Carbachol; Chloride Channels; Colforsin; Colonic Neoplasms; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprostone; Enzyme Activation; Humans; Isoproterenol; Membrane Proteins; Mutation; Second Messenger Systems; Transformation, Genetic; Tumor Cells, Cultured; Vasoactive Intestinal Peptide; Zinc | 1995 |
Activation of cAMP-dependent pathways in human airway smooth muscle cells inhibits TNF-alpha-induced ICAM-1 and VCAM-1 expression and T lymphocyte adhesion.
Topics: Asthma; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; GTP-Binding Proteins; Humans; Intercellular Adhesion Molecule-1; Isoproterenol; Lymphocyte Activation; Muscle, Smooth; T-Lymphocytes; Trachea; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 1995 |
Retinoic acid inhibits basal and interferon-gamma-induced expression of intercellular adhesion molecule 1 in monocytic cells.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Bucladesine; Calcimycin; Calcitriol; Cell Differentiation; Cell Line; Colforsin; Dinoprostone; Enzyme Induction; Gene Expression; Humans; Indomethacin; Intercellular Adhesion Molecule-1; Interferon-gamma; Lipopolysaccharide Receptors; Monocytes; Prostaglandin-Endoperoxide Synthases; Receptors, IgE; RNA, Messenger; Tretinoin | 1995 |
Role of F-actin in the activation of Na(+)-K(+)-Cl- cotransport by forskolin and vasopressin in mouse kidney cultured thick ascending limb cells.
Topics: 1-Methyl-3-isobutylxanthine; Actins; Animals; Arginine Vasopressin; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Cytoskeleton; Dinoprostone; Diuretics; Ion Transport; Isoproterenol; Loop of Henle; Male; Mice; Nocodazole; Ouabain; Parathyroid Hormone; Phalloidine; Potassium; Sodium | 1994 |
Interleukin-1 beta induces cyclic AMP formation in isolated human osteoblasts: a signalling mechanism that is not related to enhanced prostaglandin formation.
Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Bone Resorption; Calcimycin; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Humans; Ilium; Indomethacin; Interleukin-1; Osteoblasts; Recombinant Proteins | 1994 |
Evidence against direct activation of chloride secretion by carbachol in the rat distal colon.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bumetanide; Carbachol; Charybdotoxin; Chlorides; Colforsin; Colon; Cyclic AMP; Dinoprostone; Drug Interactions; Drug Synergism; Female; Indomethacin; Intestinal Mucosa; Ion Channels; Potassium Channel Blockers; Rats; Regression Analysis; Scorpion Venoms; Tetrodotoxin; Thionucleotides | 1995 |
Effect of PGE2 and of agents that raise cAMP levels on macrophage activation induced by IFN-gamma and TNF-alpha.
Topics: Adenosine; Amino Acid Oxidoreductases; Animals; Bucladesine; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression; Hematopoietic Stem Cells; Humans; Interferon-gamma; Kinetics; Leishmania; Macrophage Activation; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Nitric Oxide Synthase; Recombinant Proteins; RNA, Messenger; Theophylline; Tumor Necrosis Factor-alpha | 1995 |
A novel neuropeptide cellular mechanism in amphibian interrenal steroidogenesis.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aromatase; Aspirin; Bucladesine; Colforsin; Dinoprost; Dinoprostone; Estradiol; Female; Gonadotropin-Releasing Hormone; Hydroxyprostaglandin Dehydrogenases; In Vitro Techniques; Interrenal Gland; Models, Biological; Palmitic Acid; Palmitic Acids; Rana esculenta; Testosterone | 1995 |
Uncoupling of the proliferation and differentiation signals mediated by the murine macrophage colony-stimulating factor receptor expressed in myeloid FDC-P1 cells.
Topics: Animals; Cell Differentiation; Cell Division; Colforsin; Cyclic AMP; Dinoprostone; Hematopoietic Stem Cells; Macrophage Colony-Stimulating Factor; Mice; Mutagenesis, Site-Directed; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Receptor, Macrophage Colony-Stimulating Factor; Recombinant Fusion Proteins; Signal Transduction; Transfection; Tyrosine | 1995 |
Inhibition of serine/threonine protein phosphatases enhances agonist-stimulated cAMP accumulation in UMR 106 osteoblast-like cells.
Topics: 1-Methyl-3-isobutylxanthine; Antifungal Agents; Colforsin; Cyclic AMP; Dinoprostone; Ethers, Cyclic; Humans; Kinetics; Marine Toxins; Okadaic Acid; Osteoblasts; Oxazoles; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Protein Serine-Threonine Kinases; Proteins; Pyrans; Spiro Compounds; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Alteration of prostaglandin E receptors in advanced breast tumour cell lines.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Breast Neoplasms; Cell Differentiation; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Estradiol; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Receptors, Prostaglandin E; Tumor Cells, Cultured | 1995 |
Retinoic acid-regulated cellular differentiation and mucin gene expression in isolated rabbit tracheal-epithelial cells in culture.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bucladesine; Calcimycin; Cell Differentiation; Cells, Cultured; Colforsin; Culture Media, Serum-Free; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Epithelium; Gene Expression Regulation; Microscopy, Electron; Microscopy, Phase-Contrast; Molecular Sequence Data; Mucins; Oligonucleotides, Antisense; Protein Synthesis Inhibitors; Rabbits; Repetitive Sequences, Nucleic Acid; RNA, Messenger; Second Messenger Systems; Stimulation, Chemical; Trachea; Tretinoin | 1995 |
The functional interaction of EGF and PDGF with bradykinin in the proliferation of human gingival fibroblasts.
Topics: Alveolar Process; Becaplermin; Bradykinin; Bucladesine; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; DNA; Dose-Response Relationship, Drug; Drug Interactions; Epidermal Growth Factor; Fibroblasts; Gingiva; Growth Inhibitors; Growth Substances; Humans; Indomethacin; Periodontal Ligament; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Recombinant Proteins; Signal Transduction | 1995 |
Differential regulatory effects of cAMP-elevating agents on human normal and neoplastic B cell functional response following ligation of surface immunoglobulin and CD40.
Topics: Adjuvants, Immunologic; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Apoptosis; B-Lymphocytes; Burkitt Lymphoma; CD40 Antigens; Cell Line, Transformed; Colforsin; Cyclic AMP; Dinoprostone; Growth Inhibitors; Herpesvirus 4, Human; Humans; Immunoglobulin D; Immunoglobulin M; Ionomycin; Palatine Tonsil; Receptors, Antigen, B-Cell; Second Messenger Systems; Tumor Cells, Cultured | 1995 |
Inhibition of luteinizing hormone-releasing hormone secretion by delta-opioid agonists in GT1-1 neuronal cells.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alprostadil; Amino Acid Sequence; Cell Line; Colforsin; Culture Media, Conditioned; Dinoprostone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gonadotropin-Releasing Hormone; Molecular Sequence Data; Naltrexone; Narcotic Antagonists; Neurons; Pyrrolidines; Receptors, Opioid, delta | 1995 |
Interleukin-1 beta induction of tissue inhibitor of metalloproteinase (TIMP-1) is functionally antagonized by prostaglandin E2 in human synovial fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Northern; Bucladesine; Cells, Cultured; Colforsin; Collagenases; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Fibroblasts; Glycoproteins; Humans; Immunoenzyme Techniques; Interleukin-1; Isoquinolines; Metalloendopeptidases; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Recombinant Proteins; RNA, Messenger; Staurosporine; Synovial Membrane; Tetradecanoylphorbol Acetate; Thionucleotides; Tissue Inhibitor of Metalloproteinases; Up-Regulation | 1995 |
Regulation of heme oxygenase mRNA in mesangial cells: prostaglandin E2 negatively modulates interleukin-1-induced heme oxygenase-1 mRNA.
Topics: Animals; Base Sequence; Cells, Cultured; Colforsin; Dinoprostone; Gene Expression Regulation; Glomerular Mesangium; Heme Oxygenase (Decyclizing); Hot Temperature; Humans; Indomethacin; Interleukin-1; Kinetics; Male; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate | 1995 |
Cyclic AMP-elevating agents negatively regulate the activation of p72syk in N-formyl-methionyl-leucyl-phenylalanine receptor signaling.
Topics: Amino Acid Sequence; Animals; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Enzyme Precursors; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein-Tyrosine Kinases; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Signal Transduction; Swine; Syk Kinase | 1995 |
Rat fibroblasts synthesize T-kininogen in response to cyclic-AMP, prostaglandin E2 and cytokines.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Cells, Cultured; Colforsin; Cytokines; Dexamethasone; Dinoprostone; Fibroblasts; Gene Expression; Kininogens; Liver; Meninges; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1995 |
Prostaglandin E2 regulation of ion transport is absent in medullary thick ascending limbs from SHR.
Topics: Absorption; Animals; Arginine Vasopressin; Bicarbonates; Biological Transport; Chlorides; Cholera Toxin; Colforsin; Dinoprostone; Hypertension; Ions; Kidney Medulla; Loop of Henle; Male; Osmolar Concentration; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetradecanoylphorbol Acetate | 1995 |
Modulation of intracellular cyclic AMP levels by different human dopamine D4 receptor variants.
Topics: Animals; Benzamides; Cell Line; CHO Cells; Clozapine; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Dopamine; Haloperidol; HeLa Cells; Humans; Raclopride; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D4; Recombinant Proteins; Salicylamides; Spiperone; Transfection | 1995 |
Prostaglandins stimulate serotonin acetylation in chick pineal cells: involvement of cyclic AMP-dependent and calcium/calmodulin-dependent mechanisms.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylation; Alprostadil; Animals; Arylamine N-Acetyltransferase; Calcium; Calmodulin; Cells, Cultured; Chickens; Cloprostenol; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Indomethacin; Kinetics; Pineal Gland; Prostaglandins; Serotonin; Sulfonamides | 1993 |
A kinase-mediated regulation of granulosa cell-derived insulin-like growth factor binding proteins (IGFBPs): disparate response sensitivities of distinct IGFBP species.
Topics: Adenylyl Cyclases; Animals; Bordetella pertussis; Carrier Proteins; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Female; Follicle Stimulating Hormone; Granulosa Cells; Insulin-Like Growth Factor Binding Proteins; Molecular Weight; Phosphotransferases; Somatomedins | 1993 |
Effect of adenylate cyclase stimulation on meiotic resumption and cyclic AMP content of zona-free and cumulus-enclosed bovine oocytes in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cattle; Cell Nucleus; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Female; Meiosis; Oocytes; Ovarian Follicle; Pertussis Toxin; Sodium Fluoride; Stimulation, Chemical; Virulence Factors, Bordetella; Zona Pellucida | 1993 |
Effects of forskolin on crypt cells of rat distal colon. Activation of nonselective cation channels in the crypt base and of a chloride conductance pathway in other parts of the crypt.
Topics: Animals; Cell Division; Chloride Channels; Colforsin; Colon; Dinoprostone; Ion Channels; Male; Membrane Potentials; Nystatin; Rats; Rats, Wistar | 1993 |
Prostaglandin E2 and other cyclic AMP elevating agents inhibit interleukin 2 gene transcription by counteracting calcineurin-dependent pathways.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcineurin; Calmodulin-Binding Proteins; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; Cyclic AMP; Dinoprostone; Gene Deletion; Gene Expression; Humans; Interleukin-2; Ionomycin; Kinetics; Mice; Phosphoprotein Phosphatases; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1993 |
Indirect inhibition by bradykinin of cyclic AMP generation in isolated rat glomeruli and mesangial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Down-Regulation; Drug Interactions; Enzyme Activation; Glomerular Mesangium; Isoproterenol; Kidney Glomerulus; Male; Pertussis Toxin; Protein Kinase C; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Homologous desensitization of histamine H2 receptors in the human gastric carcinoma cell line MKN-45.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cimetidine; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Histamine; Histamine H2 Antagonists; Humans; Kinetics; Receptors, Histamine H2; Sodium Fluoride; Stomach Neoplasms; Tumor Cells, Cultured | 1993 |
Contractile effects of prostanoids on fetal rabbit ductus arteriosus.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Analysis of Variance; Animals; Colforsin; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Ductus Arteriosus; Female; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Pregnancy; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E, Synthetic; Rabbits; Receptors, Prostaglandin; Thromboxane A2; Thromboxanes; Vasoconstrictor Agents | 1995 |
Hyperosmolality inhibits bicarbonate absorption in rat medullary thick ascending limb via a protein-tyrosine kinase-dependent pathway.
Topics: Absorption; Alkaloids; Animals; Arginine Vasopressin; Benzoquinones; Bicarbonates; Colforsin; Dinoprostone; Drug Interactions; Genistein; Isoflavones; Kidney Medulla; Lactams, Macrocyclic; Loop of Henle; Mannitol; Molybdenum; Osmolar Concentration; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Sodium Chloride; Staurosporine | 1995 |
Modulation of cyclic AMP production by strial marginal cells from gerbil in culture.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Alprostadil; Analysis of Variance; Animals; Cells, Cultured; Colforsin; Collagen; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Endolymph; Epinephrine; Gerbillinae; Immunohistochemistry; Isoproterenol; Male; Microscopy, Electron; Stria Vascularis; Vasopressins | 1994 |
Production of PGE2 by bovine cultured airway smooth muscle cells: regulation by cAMP.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Albuterol; Animals; Bradykinin; Bucladesine; Cattle; Cell Count; Colforsin; Culture Media; Cyclic AMP; Cycloheximide; Dinoprostone; In Vitro Techniques; Muscle, Smooth; Phosphodiesterase Inhibitors; Trachea | 1995 |
Autoregulation of inducible prostaglandin G/H synthase in osteoblastic cells by prostaglandins.
Topics: 3T3 Cells; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Blotting, Western; Cells, Cultured; Colforsin; Dinoprost; Dinoprostone; DNA, Complementary; Enzyme Induction; Mice; Nucleic Acid Hybridization; Osteoblasts; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1995 |
Non-steroidal anti-inflammatory drugs and prostaglandin effects on pepsinogen secretion by dispersed human peptic cells.
Topics: Acetylcholine; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colforsin; Dinoprostone; Drug Synergism; Female; Gastric Mucosa; Histamine; Humans; Ibuprofen; In Vitro Techniques; Male; Middle Aged; Pepsinogens; Prostaglandin D2; Stimulation, Chemical | 1995 |
Heterogeneity of murine adherent interleukin-2-activated killer cells. Differential effect of prostaglandin E2 and forskolin.
Topics: Animals; Cell Fractionation; Cell Line; Cell Size; Centrifugation, Density Gradient; Colforsin; Cytoplasmic Granules; Cytotoxicity, Immunologic; Dinoprostone; Esterases; Interleukin-2; Killer Cells, Natural; Lymphocyte Activation; Lymphocyte Subsets; Mice; Mice, Inbred C3H; Povidone; Silicon Dioxide | 1995 |
Retinoic acid modulation of mucin mRNA in rat tracheal explants: response to actinomycin D, cycloheximide, signal transduction effectors and antisense oligodeoxynucleotide.
Topics: Animals; Base Sequence; Bucladesine; Colforsin; Cycloheximide; Dactinomycin; Dinoprostone; Microscopy, Electron; Molecular Sequence Data; Mucins; Oligonucleotides, Antisense; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Trachea; Tretinoin | 1994 |
Cyclic AMP regulation of annexins I, II, V synthesis and localization in cultured porcine thyroid cells.
Topics: Animals; Annexin A1; Annexin A2; Annexin A5; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Phospholipases A; Phospholipases A2; Swine; Thyroid Gland; Thyrotropin | 1994 |
The sensitivity of IL-4 production for cAMP inducers is lost in CD4+ T cells from aged mice.
Topics: Aging; Animals; Antigen-Presenting Cells; CD4-Positive T-Lymphocytes; Cells, Cultured; Colforsin; Concanavalin A; Cyclic AMP; Dinoprostone; Enzyme Induction; Immunophenotyping; Interleukin-2; Interleukin-4; Lymphocyte Activation; Male; Mice; Mice, Inbred CBA | 1993 |
The activation of protein kinase C prevents PGE2-induced inhibition of AVP-dependent cAMP accumulation in the rat outer medullary collecting tubule.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Arginine Vasopressin; Clonidine; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Kidney Medulla; Kidney Tubules, Collecting; Male; Osmolar Concentration; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1993 |
Functional behavior of the beta-adrenergic receptor-adenylyl cyclase system in rabbit airway epithelium.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Betaxolol; Binding, Competitive; Bradykinin; Colforsin; Cyclic AMP; Dinoprostone; Epithelial Cells; Epithelium; Glycerol; Isoproterenol; Kinetics; Pindolol; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Trachea | 1994 |
Regulation of beta-agonist- and prostaglandin E2-mediated adenylyl cyclase activity in human airway epithelial cells.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Binding Sites; Bronchi; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Epithelial Cells; Epithelium; Humans; Isoproterenol; Receptors, Adrenergic, beta; Signal Transduction | 1994 |
Differential actions of prostaglandins in separate cell populations from fetal rat bone.
Topics: Animals; Bone and Bones; Cell Division; Cells, Cultured; Colforsin; Collagen; Cyclic AMP; Dinoprostone; DNA; Female; Fetus; Insulin-Like Growth Factor I; Pregnancy; Prostaglandins; Rats; Rats, Sprague-Dawley; Signal Transduction; Transforming Growth Factor beta | 1994 |
Activation and attenuation of transcription factor NF-kB in mouse glomerular mesangial cells in response to tumor necrosis factor-alpha, immunoglobulin G, and adenosine 3':5'-cyclic monophosphate. Evidence for involvement of reactive oxygen species.
Topics: Acetophenones; Animals; Base Sequence; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; DNA; Free Radical Scavengers; Gene Expression Regulation; Glomerular Mesangium; Immunoglobulin G; Mice; Molecular Sequence Data; NF-kappa B; Reactive Oxygen Species; Receptors, IgG; Superoxides; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 1994 |
Down-regulation of G alpha s in human myometrium in term and preterm labor: a mechanism for parturition.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adult; Colforsin; Cyclic AMP; Dinoprostone; Female; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Immunoblotting; Labor, Obstetric; Middle Aged; Myometrium; Obstetric Labor, Premature; Pregnancy | 1994 |
Defective glomerular beta-adrenergic signal transmission in spontaneously diabetic rats.
Topics: Animals; Blood Glucose; Colforsin; Cyclic AMP; Diabetes Mellitus, Type 1; Dinoprostone; Histamine; Isoproterenol; Kidney Glomerulus; Rats; Rats, Inbred BB; Rats, Mutant Strains; Receptors, Adrenergic, beta; Signal Transduction | 1994 |
Effect of prostaglandin E2 and other intracellular cyclic AMP elevating agents on the mitogen induced mouse splenocyte proliferation in a serum free culture condition.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Concanavalin A; Culture Media, Serum-Free; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Female; GTP-Binding Proteins; Indomethacin; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred BALB C; Spleen | 1994 |
The C-terminus of the prostaglandin-E-receptor EP3 subtype is essential for activation of GTP-binding protein.
Topics: Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; GTP Phosphohydrolases; GTP-Binding Proteins; Molecular Sequence Data; Mutation; Precipitin Tests; Receptors, Prostaglandin E | 1994 |
Costimulatory signals modulate the antiproliferative effects of agents that elevate cAMP in T cells.
Topics: Adenylyl Cyclases; Adult; Antibodies, Monoclonal; Bucladesine; CD28 Antigens; CD3 Complex; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Humans; Immunosuppressive Agents; Interleukin-2; Isoproterenol; Lymphocyte Activation; Signal Transduction; T-Lymphocytes | 1994 |
Prostaglandin E2 activates clusters of apical Cl- channels in principal cells via a cyclic adenosine monophosphate-dependent pathway.
Topics: Animals; Arginine Vasopressin; Bucladesine; Calcium-Transporting ATPases; Cell Membrane; Cells, Cultured; Chloride Channels; Colforsin; Cyclic AMP; Dinoprostone; Electric Conductivity; Kidney Cortex; Kidney Tubules, Collecting; Membrane Potentials; Rabbits; Terpenes; Thapsigargin | 1994 |
Effect of insulin on water and urea transport in the inner medullary collecting duct.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Biological Transport; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; In Vitro Techniques; Insulin; Kidney Medulla; Kidney Tubules, Collecting; Male; Polymyxin B; Rats; Rats, Wistar; Urea; Vasopressins; Water | 1994 |
Forskolin does not augment the bradykinin response of canine visceral polymodal receptors in vitro.
Topics: Adenylyl Cyclases; Animals; Aspirin; Bradykinin; Colforsin; Dinoprostone; Dogs; Drug Interactions; Enzyme Activation; In Vitro Techniques; Male; Nociceptors; Receptors, Cell Surface; Testis | 1994 |
Nonspecific refractoriness to adenylyl cyclase stimulation in alveolar macrophages from infants with recurrent bronchiolitis.
Topics: Adenylyl Cyclases; Albuterol; Asthma; Bronchiolitis; Bronchoalveolar Lavage Fluid; Bronchoscopy; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Infant; Macrophages, Alveolar; Male; Recurrence; Respiratory Sounds; Stimulation, Chemical | 1994 |
Enhancement of adenylate cyclase stimulation by prostaglandin E receptor EP3 subtype isoforms with different efficiencies.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Colforsin; Dinoprostone; Enzyme Activation; Mice; Pertussis Toxin; Receptors, Prostaglandin E; Recombinant Proteins; Signal Transduction; Virulence Factors, Bordetella | 1994 |
A novel synergistic stimulation of Swiss 3T3 cells by extracellular ATP and mitogens with opposite effects on cAMP levels.
Topics: 3T3 Cells; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Arachidonic Acid; Cell Division; Cell Nucleus; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; DNA; Drug Synergism; Epidermal Growth Factor; Kinetics; Lysophospholipids; Mice; Mitogens; Phosphatidic Acids; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymidine | 1994 |
Inhibition of the transendothelial migration of human T lymphocytes by prostaglandin E2.
Topics: Bucladesine; Cell Adhesion; Cell Movement; Colforsin; Cyclic AMP; Diffusion; Dinoprostone; Endothelium, Vascular; Humans; In Vitro Techniques; Inflammation; Integrins; Interleukin-1; Lymphocyte Activation; Mannitol; T-Lymphocytes | 1994 |
Vasoactive intestinal peptide and forskolin stimulate interleukin 6 production by rat cortical astrocytes in culture via a cyclic AMP-dependent, prostaglandin-independent mechanism.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Astrocytes; Bucladesine; Carbazoles; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Dinoprostone; Indoles; Interleukin-6; Prostaglandins; Pyrroles; Radioimmunoassay; Rats; Rats, Wistar; Vasoactive Intestinal Peptide | 1994 |
Differential regulation of inducible and constitutive prostaglandin endoperoxide synthase in osteoblastic MC3T3-E1 cells.
Topics: Animals; Cell Line; Colforsin; Culture Media; Culture Media, Serum-Free; Cycloheximide; Dactinomycin; Dinoprostone; DNA; Enzyme Induction; Hydrocortisone; Kinetics; Mice; Osteoblasts; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta | 1993 |
Tumor necrosis factor alpha modulates parathyroid hormone action in UMR-106-01 osteoblastic cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bone Remodeling; Calcium; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Mice; Osteoblasts; Parathyroid Hormone; Pertussis Toxin; Rats; Receptors, Parathyroid Hormone; Recombinant Proteins; Signal Transduction; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 1993 |
Histamine H2 receptor mediates keratan sulfate secretion in rabbit chondrocytes: role of cAMP.
Topics: Animals; Bucladesine; Cartilage, Articular; Cells, Cultured; Cholera Toxin; Cimetidine; Colforsin; Cyclic AMP; Dimaprit; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Keratan Sulfate; Kinetics; Methylhistamines; Parathyroid Hormone; Proteoglycans; Rabbits; Receptors, Histamine H2; Sulfates; Sulfur Radioisotopes | 1993 |
PGE2: a mediator of corneal endothelial wound repair in vitro.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Endothelium, Corneal; Enzyme Activation; Indomethacin; Osmolar Concentration; Rabbits; Wound Healing | 1994 |
Characterisation of the effect of oxygen tension on response of fetal rabbit ductus arteriosus to vasodilators.
Topics: Adenosine; Animals; Atrial Natriuretic Factor; Benzopyrans; Colforsin; Cromakalim; Culture Techniques; Cyclooxygenase Inhibitors; Dinoprostone; Ductus Arteriosus; Epoprostenol; Flurbiprofen; Indomethacin; Nifedipine; Nitroprusside; Norepinephrine; Oxygen; Pyrroles; Rabbits; Vasodilator Agents | 1993 |
Differential effects of phorbol myristate acetate and dexamethasone on protein kinase C activity and eicosanoids production in cultured rat astrocytes.
Topics: Alkaloids; Animals; Astrocytes; Biomarkers; Cells, Cultured; Colforsin; Dexamethasone; Dinoprostone; Eicosanoids; Female; Fluorescent Antibody Technique; Neuroglia; Pregnancy; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Changes in adenylyl cyclase activity in human endometrium during the menstrual cycle and in human decidua during pregnancy.
Topics: Adenylyl Cyclases; Adult; Colforsin; Corpus Luteum; Culture Techniques; Decidua; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Endometrium; Fallopian Tubes; Female; Humans; Isoproterenol; Menstrual Cycle; Middle Aged; Myometrium; Pregnancy | 1993 |
Up-regulation of oxytocin receptors in rabbit amnion by adenosine 3',5'-monophosphate.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amnion; Animals; Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; Dinoprostone; Drug Synergism; Female; Isoquinolines; Oxytocin; Piperazines; Pregnancy; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Receptors, Angiotensin; Receptors, Oxytocin; Tetradecanoylphorbol Acetate; Up-Regulation | 1993 |
Tyrphostins inhibit follicle-stimulating hormone-mediated functions in cultured rat ovarian granulosa cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine Nucleotides; Animals; Benzylidene Compounds; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Induction; Female; Follicle Stimulating Hormone; Granulosa Cells; Nitriles; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Receptors, LH; Signal Transduction; Tyrphostins | 1993 |
Transcription of the gene for parathyroid hormone-related peptide from the human is activated through a cAMP-dependent pathway by prostaglandin E1 in HTLV-I-infected T cells.
Topics: Alprostadil; Analysis of Variance; Bucladesine; Cell Line; Cell Transformation, Viral; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Gene Expression Regulation, Viral; Genes; Human T-lymphotropic virus 1; Humans; Kinetics; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Protein Biosynthesis; Proteins; RNA, Messenger; T-Lymphocytes; Time Factors; Transcription, Genetic | 1993 |
Beta 2-adrenoceptor desensitization in cultured human airway smooth muscle.
Topics: Cells, Cultured; Colforsin; Cyclic AMP; Dexamethasone; Dinoprostone; Humans; Isoproterenol; Muscle, Smooth; Receptors, Adrenergic, beta; Time Factors | 1993 |
Structural and functional characterization of striated ducts isolated from the rabbit mandibular salivary gland.
Topics: Acetylcholine; Animals; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Histological Techniques; In Vitro Techniques; Isoproterenol; Male; Microscopy, Electron; Norepinephrine; Phenylephrine; Rabbits; Submandibular Gland | 1993 |
Role of cAMP in regulating cytotoxic T lymphocyte adhesion and motility.
Topics: Actins; Calcium; Cell Adhesion; Cell Movement; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cytotoxicity, Immunologic; Dinoprostone; Drug Synergism; Humans; Immunity, Cellular; In Vitro Techniques; Microtubules; T-Lymphocytes, Cytotoxic | 1993 |
Forskolin inhibits platelet-activating factor binding to platelet receptors independently of adenylyl cyclase activation.
Topics: Adenylyl Cyclases; Animals; Blood Platelets; Cell Membrane; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; GTP-Binding Proteins; In Vitro Techniques; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Rabbits | 1993 |
Estradiol up-regulates the stimulatory GTP-binding protein expression in the MCF-7 human mammary carcinoma cell line.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Breast Neoplasms; Calcitonin; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Estradiol; GTP-Binding Proteins; Humans; Isoproterenol; Pertussis Toxin; Tumor Cells, Cultured; Up-Regulation; Virulence Factors, Bordetella | 1993 |
Proliferation of mouse primordial germ cells in vitro: a key role for cAMP.
Topics: Adrenocorticotropic Hormone; Animals; Bucladesine; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Embryo, Mammalian; Germ Cells; Kinetics; Mice; Protein Kinase Inhibitors; Thionucleotides; Time Factors | 1993 |
Two isoforms of prostaglandin E receptor EP3 subtype. Different COOH-terminal domains determine sensitivity to agonist-induced desensitization.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; CHO Cells; Chromatography, Gel; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Down-Regulation; Kinetics; Macromolecular Substances; Mice; Molecular Sequence Data; Receptors, Prostaglandin; Receptors, Prostaglandin E; Recombinant Proteins; Transfection | 1993 |
Agonistic and antagonistic effects of cholera toxin on human B lymphocyte proliferation.
Topics: B-Lymphocytes; Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Humans; Immunoglobulin M; In Vitro Techniques; Interleukin-2; Interleukin-4; Lymphocyte Activation; Palatine Tonsil; Receptors, Interleukin-2 | 1993 |
Reduction by arachidonic acid of prostaglandin I2-induced cyclic AMP formation. Involvement of prostaglandins E2 and F2 alpha.
Topics: Arachidonic Acid; Aspirin; Blood Platelets; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Drug Interactions; Epoprostenol; Humans; Pentanoic Acids; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Pyridines; Thromboxane B2 | 1993 |
Stimulation of aged human lung fibroblasts by extracellular ATP via suppression of arachidonate metabolism.
Topics: Adenosine Triphosphate; Arachidonic Acid; Bradykinin; Cell Division; Cell Line; Cellular Senescence; Colforsin; Cyclic AMP; Dinoprostone; DNA Replication; Embryo, Mammalian; Fibroblasts; Humans; Insulin; Kinetics; Lung; Lysophospholipids; Phorbol 12,13-Dibutyrate; Protein Kinase C; Time Factors | 1993 |
Phorbol ester, prostaglandin E2, forskolin and okadaic acid differentially modulate interleukin-4-versus interleukin-2-dependent immunoglobulin induction in human cellular models, in contrast to other selected modifiers of cellular activation.
Topics: Antibodies, Monoclonal; B-Lymphocytes; Cells, Cultured; Colforsin; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Ethers, Cyclic; Humans; Immunoglobulin E; Immunoglobulin G; Immunoglobulins; Interleukin-2; Interleukin-4; Interleukins; Lymphocyte Activation; Okadaic Acid; Phosphoprotein Phosphatases; Tetradecanoylphorbol Acetate | 1993 |
Endogenous prostaglandin E2 mediates inhibition of rat thick ascending limb Cl reabsorption in chronic hypercalcemia.
Topics: Alkaloids; Animals; Biological Transport, Active; Chlorides; Chronic Disease; Colforsin; Cyclic AMP; Dihydrotachysterol; Dinoprostone; Furosemide; Hypercalcemia; In Vitro Techniques; Indomethacin; Kidney Medulla; Kidney Tubules, Collecting; Male; Perfusion; Rats; Rats, Sprague-Dawley; Staurosporine | 1993 |
Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cytokines; Dinoprostone; Dose-Response Relationship, Drug; Humans; Lymphocyte Activation; Mice; T-Lymphocytes, Helper-Inducer | 1993 |
Transforming growth factor-beta modulates the parathyroid hormone-related protein-induced responses in renal epithelial cells.
Topics: Animals; Biological Transport; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Drug Interactions; Epithelium; Humans; Kidney; Kinetics; Opossums; Parathyroid Hormone-Related Protein; Phosphates; Proteins; Transforming Growth Factor beta | 1993 |
Protein kinase A activators inhibit agonist induced prostaglandin production in human amnion.
Topics: Adenylyl Cyclases; Amnion; Bucladesine; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Female; Fetus; Humans; In Vitro Techniques; Isoproterenol; Oxytocin; Pregnancy; Pregnancy Trimester, Third; Protein Kinases; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Impaired beta-adrenergic receptor activation of adenylyl cyclase in airway smooth muscle in the basenji-greyhound dog model of airway hyperresponsiveness.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Bronchial Hyperreactivity; Bucladesine; Cholera Toxin; Colforsin; Dinoprostone; Disease Models, Animal; Dogs; Enzyme Activation; Immunoblotting; Isoproterenol; Lung; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Radioimmunoassay; Receptors, Adrenergic, beta; Trachea | 1993 |
Protection by phosphodiesterase inhibitors against endotoxin-induced liver injury in galactosamine-sensitized mice.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Galactosamine; Hepatitis; Lipopolysaccharides; Liver; Macrophages; Male; Mice; Phosphodiesterase Inhibitors; Pyridazines; Pyrrolidinones; Rolipram; Shock, Septic; Tumor Necrosis Factor-alpha | 1993 |
Elevated post-stimulatory intracellular adenosine 3,5-cyclic monophosphate (cAMP) levels are found in peripheral blood cells after ABMT.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Female; Humans; Leukemia, Monocytic, Acute; Leukocytes, Mononuclear; Lymphocyte Subsets; Male; Middle Aged; Postoperative Period; Stimulation, Chemical; Time Factors | 1993 |
Roles of Ca2+ and protein kinase C in regulation of prostaglandin E2 release by cultured rabbit gastric epithelial cells.
Topics: 2-Chloroadenosine; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Drug Interactions; Epithelium; Female; Gallic Acid; Gastric Mucosa; Male; Protein Kinase C; Quinacrine; Rabbits; Stomach | 1993 |
Role of protein kinase A in LPS-induced activation of NF-kappa B proteins of a mouse macrophage-like cell line, J774.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Base Sequence; Bucladesine; Cholera Toxin; Colforsin; Consensus Sequence; Cyclic AMP; Dinoprostone; Female; Gene Expression Regulation, Neoplastic; Isoquinolines; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neoplasm Proteins; NF-kappa B; Phosphorylation; Piperazines; Protein Kinases; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription Factor RelB; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Effects of vitamin D3 on signaling by prostaglandin E2 in osteoblast-like cells.
Topics: Animals; Cell Line; Cholecalciferol; Colforsin; Cyclic AMP; Dinoprostone; GTP-Binding Proteins; Kinetics; Osteoblasts; Phosphatidylinositols; Signal Transduction; Sodium Fluoride | 1993 |
Effects of retinoic acid on signalling by prostaglandin E2 in osteoblast-like cells.
Topics: 3T3 Cells; Animals; Clone Cells; Colforsin; Cyclic AMP; Dinoprostone; Inositol Phosphates; Kinetics; Mice; Osteoblasts; Signal Transduction; Sodium Fluoride; Tretinoin | 1993 |
Up-regulation of oxytocin receptors in rabbit amnion by glucocorticoids: potentiation by cyclic adenosine 3',5'-monophosphate.
Topics: Amnion; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Glucocorticoids; Hydrocortisone; Intracellular Membranes; Oxytocin; Rabbits; Receptors, Oxytocin; Transforming Growth Factor alpha; Up-Regulation | 1993 |
Agonist-induced effects on cyclic AMP metabolism are affected in pigment epithelial cells of the Royal College of Surgeons rat.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Alprostadil; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Fibroblast Growth Factor 2; Imidazoles; Isoproterenol; Kinetics; Melatonin; Pigment Epithelium of Eye; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta-2; Receptors, Purinergic P1; Serotonin | 1995 |
Role of cyclic AMP in prostaglandin mediated responses in the neural retina.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Dinoprostone; Dopamine; Male; Rabbits; Receptors, Prostaglandin E; Retina | 1995 |
Activators of protein kinase C but not of phospholipase C modulate adenylate cyclase-responses of normal pig epidermis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenylyl Cyclases; Animals; Bradykinin; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Epidermal Growth Factor; Epidermis; Epinephrine; Histamine; Isoquinolines; Keratinocytes; Piperazines; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1995 |
Down-regulation and differential restoration of cAMP responses upon transient phorbol ester treatment of primary osteoblastic cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Down-Regulation; Enzyme Activation; Kinetics; Osteoblasts; Parathyroid Hormone; Phorbol Esters; Phosphodiesterase Inhibitors; Protein Kinase C; Rats; Receptors, Parathyroid Hormone; Signal Transduction; Skull; Tetradecanoylphorbol Acetate | 1995 |
The metabolic effects of interleukin 1 beta on human bone marrow adipocytes.
Topics: Acetates; Adenylyl Cyclases; Adipose Tissue; Bone Marrow Cells; Cells, Cultured; Colforsin; Dinoprostone; Hematopoiesis; Humans; Indomethacin; Interleukin-1; Lipid Metabolism; Lipolysis; Triglycerides | 1995 |
Prostaglandin E2 requirement for transforming growth factor beta 1 inhibition of elicited macrophage 14 kDa phospholipase A2 release.
Topics: Animals; Cells, Cultured; CHO Cells; Colforsin; Cricetinae; Culture Media, Conditioned; Cyclooxygenase Inhibitors; Dinoprostone; Indomethacin; Macrophages, Peritoneal; Male; Phospholipases A; Phospholipases A2; Transforming Growth Factor beta | 1995 |
Inhibition of muscarinic stimulated phosphoinositide hydrolysis in the rat parotid gland by cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Animals; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Drug Interactions; Hydrolysis; Isoproterenol; Male; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Parotid Gland; Phosphatidylinositols; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Sodium Fluoride; Stimulation, Chemical | 1996 |
The actions of prostaglandin E2 on potassium currents in rat tail artery vascular smooth muscle cells: regulation by protein kinase A and protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Male; Muscle, Smooth, Vascular; Potassium Channels; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Tail; Tetradecanoylphorbol Acetate | 1996 |
Regulation of the nuclear factor of activated T cells in stably transfected Jurkat cell clones.
Topics: Alkaline Phosphatase; Bucladesine; Clone Cells; Colforsin; Cyclosporine; Dinoprostone; DNA-Binding Proteins; Enzyme Inhibitors; Ethers, Cyclic; Female; Humans; Immunosuppressive Agents; Kinetics; Lymphocyte Activation; Marine Toxins; NFATC Transcription Factors; Nuclear Proteins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Placenta; Pregnancy; Protein Phosphatase 1; Recombinant Proteins; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1996 |
Transforming growth factor-beta 1 induces transcriptional down-regulation of m2 muscarinic receptor gene expression.
Topics: Adenylyl Cyclases; Cell Line; Colforsin; Cycloheximide; Dinoprostone; Down-Regulation; Humans; Protein Synthesis Inhibitors; Receptors, Muscarinic; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta | 1996 |
Effects of prostaglandins on deoxyribonucleic acid and aggrecan synthesis in the RCJ 3.1C5.18 chondrocyte cell line: role of second messengers.
Topics: Aggrecans; Alprostadil; Animals; Bucladesine; Calcium; Cartilage; Cell Line; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; DNA; Extracellular Matrix Proteins; Lectins, C-Type; Prostaglandins; Protein Kinase C; Proteoglycans; Rats; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1996 |
Transcriptional regulation of insulin-like growth factor-binding protein-5 by prostaglandin E2 in osteoblast cells.
Topics: Animals; Base Sequence; Bone and Bones; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Female; Gene Expression Regulation; Insulin-Like Growth Factor Binding Protein 5; Isoquinolines; Molecular Sequence Data; Osteoblasts; Pregnancy; Promoter Regions, Genetic; Protein Kinase C; Rats; RNA, Heterogeneous Nuclear; RNA, Messenger; Sulfonamides; Transcription, Genetic | 1996 |
Mechanism of cytokine-induced modulation of beta-adrenoceptor responsiveness in airway smooth muscle.
Topics: Acetylcholine; Adenylate Cyclase Toxin; Animals; Cell Membrane; Colforsin; Cytokines; Diamines; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression; GTP-Binding Proteins; In Vitro Techniques; Interleukin-1; Interleukin-2; Isometric Contraction; Isoproterenol; Kinetics; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Pertussis Toxin; Rabbits; Receptors, Adrenergic, beta; Signal Transduction; Trachea; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 1996 |
Histamine inhibits tumor necrosis factor alpha release by mast cells through H2 and H3 receptors.
Topics: Animals; Antibody Specificity; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Cytotoxins; Dinoprostone; Dose-Response Relationship, Drug; Histamine; Macrophages, Peritoneal; Male; Mast Cells; Rats; Rats, Sprague-Dawley; Receptors, Histamine H2; Receptors, Histamine H3; Sensitivity and Specificity; Time Factors; Tumor Necrosis Factor-alpha | 1996 |
Effect of pertussis toxin and PGE2 on the functioning of the IL-2 promoter in interleukin-1 treated EL4.NOB-1 thymoma cells.
Topics: Animals; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; Dinoprostone; Gene Expression; Interleukin-1; Interleukin-2; Mice; Pertussis Toxin; Plasmids; Promoter Regions, Genetic; Recombinant Proteins; Signal Transduction; Thymoma; Thymus Neoplasms; Transfection; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1996 |
Histamine receptors in neoplastic transformation: studies in human cell lines.
Topics: Analysis of Variance; Binding Sites; Cell Transformation, Neoplastic; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Histamine; Histamine Agonists; Humans; Lethal Dose 50; Oxytocics; Phosphatidylinositols; Receptors, Histamine H1; Receptors, Histamine H2; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases | 1996 |
Modulation of the hyperpolarization-activated current (Ih) by cyclic nucleotides in guinea-pig primary afferent neurons.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adenosine; Adenosine Monophosphate; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dibutyryl Cyclic GMP; Dinoprostone; Guinea Pigs; In Vitro Techniques; Ion Channels; Neurons, Afferent; Nodose Ganglion; Nucleotides, Cyclic; Patch-Clamp Techniques; Phosphorylation; Second Messenger Systems; Thionucleotides; Trigeminal Ganglion | 1996 |
Paradoxical facilitation of acetylcholine release from parasympathetic nerves innervating guinea-pig trachea by isoprenaline.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Atropine; Colforsin; Cyclic AMP; Dinoprostone; Electric Stimulation; Guinea Pigs; Humans; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Neuromuscular Junction; Parasympathetic Nervous System; Phosphodiesterase Inhibitors; Synaptic Transmission; Trachea | 1996 |
Selective enhancement by serum factors of cyclic AMP accumulation in rat microglial cultures.
Topics: Adrenergic beta-Agonists; Animals; Astrocytes; Blood Physiological Phenomena; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Culture Media, Serum-Free; Cyclic AMP; Dinoprostone; Isoproterenol; Microglia; Rats; Rats, Wistar; Stimulation, Chemical | 1996 |
Cyclic adenosine-3',5'-monophosphate production is greater in rabbit duodenal crypt than in villus cells.
Topics: Animals; Bicarbonates; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Duodenum; In Vitro Techniques; Intestinal Mucosa; Male; Microvilli; Rabbits; Vasoactive Intestinal Peptide | 1996 |
The effect of prostaglandin E2 and prostaglandin F2 alpha on ovarian tissue in the Florida crayfish Procambarus paeninsulanus.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arachidonic Acid; Astacoidea; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Female; Muscle Contraction; Ovary; Phosphorylation | 1995 |
Effects of secretory products of breast cancer cells on osteoblast-like cells.
Topics: Adenocarcinoma; Breast Neoplasms; Cell Division; Colforsin; Culture Media, Conditioned; Cyclic AMP; Dinoprostone; Female; Humans; Osteoblasts; Osteolysis; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Proteins; Transforming Growth Factor beta; Tumor Cells, Cultured | 1996 |
Phosphorylation of CREB in ovine pars tuberalis is regulated both by cyclic AMP-dependent and cyclic AMP-independent mechanisms.
Topics: Adenosine; Animals; Blood Physiological Phenomena; Blotting, Western; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dinoprostone; Female; Immunohistochemistry; Male; Melatonin; Phosphorylation; Pituitary Gland, Anterior; Serine; Sheep | 1996 |
Opposite effects of increased intracellular cyclic AMP on the heat and bradykinin responses of canine visceral polymodal receptors in vitro.
Topics: Animals; Body Temperature Regulation; Bradykinin; Colforsin; Cyclic AMP; Dinoprostone; Dogs; In Vitro Techniques; Male; Nociceptors; Testis | 1996 |
PGE2 modulates the tetrodotoxin-resistant sodium current in neonatal rat dorsal root ganglion neurones via the cyclic AMP-protein kinase A cascade.
Topics: Action Potentials; Animals; Animals, Newborn; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Electrophysiology; Ganglia, Spinal; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channels; Tetrodotoxin | 1996 |
The effect of bile acid on the activation of amiloride-sensitive sodium channels in frog skin.
Topics: Amiloride; Animals; Cholagogues and Choleretics; Colforsin; Cyclic AMP; Deoxycholic Acid; Dinoprostone; Diuretics; Rana ridibunda; Skin; Sodium Channels; Theophylline; Vasodilator Agents | 1996 |
Prostaglandin E2 both stimulates and inhibits adenyl cyclase on platelets: comparison of effects on cloned EP4 and EP3 prostaglandin receptor subtypes.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Blood Platelets; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Humans; Iloprost; Platelet Aggregation Inhibitors; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype | 1996 |
Regulation of expression of matrix metalloproteinase-9 in early human T cells of the HSB.2 cultured line by the EP3 subtype of prostaglandin E2 receptor.
Topics: Adenine; Alprostadil; Blotting, Northern; Bucladesine; Calcium; Cell Line; Colforsin; Collagenases; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Leukemia, T-Cell; Matrix Metalloproteinase 9; Misoprostol; Prostaglandins E, Synthetic; Receptors, Prostaglandin E; RNA, Messenger; T-Lymphocytes; Thapsigargin; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Regulation of HCO3- absorption by prostaglandin E2 and G proteins in rat medullary thick ascending limb.
Topics: Absorption; Animals; Arginine Vasopressin; Bicarbonates; Cholera Toxin; Colforsin; Dinoprostone; GTP-Binding Proteins; In Vitro Techniques; Kidney Medulla; Loop of Henle; Male; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Virulence Factors, Bordetella | 1996 |
Prostaglandin E2 induction of binding activity to CRE and AP-2 elements in human T lymphocytes.
Topics: 1-Methyl-3-isobutylxanthine; Binding Sites; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dinoprostone; DNA; DNA-Binding Proteins; Enhancer Elements, Genetic; Enzyme Inhibitors; Humans; Jurkat Cells; Okadaic Acid; Phosphorylation; Promoter Regions, Genetic; T-Lymphocytes; Transcription Factor AP-2; Transcription Factors; Transfection | 1996 |
Estrogen biosynthesis proximal to a breast tumor is stimulated by PGE2 via cyclic AMP, leading to activation of promoter II of the CYP19 (aromatase) gene.
Topics: Adipose Tissue; Aromatase; Breast Neoplasms; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Estrogens; Female; Gene Expression Regulation; Humans; Promoter Regions, Genetic; Stromal Cells; Tetradecanoylphorbol Acetate | 1996 |
Pharmacological activation changes stiffness of cultured human airway smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Actins; Bradykinin; Bronchodilator Agents; Bucladesine; Carbachol; Cells, Cultured; Colforsin; Collagen; Cytoskeleton; Dinoprostone; Histamine; Humans; Isoproterenol; Kinetics; Magnetics; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Myosins; Potassium Chloride; Substance P; Time Factors; Trachea | 1996 |
Immortalized hypothalamic neurons express metabotropic glutamate receptors positively coupled to cyclic AMP formation.
Topics: Animals; Cell Division; Cell Line, Transformed; Colforsin; Cyclic AMP; Cycloleucine; Dinoprostone; Excitatory Amino Acid Agonists; Gonadotropin-Releasing Hormone; Hypothalamus; Mice; Neurons; Norepinephrine; Phosphatidylinositols; Quisqualic Acid; Receptors, Metabotropic Glutamate | 1996 |
Interleukin-1 beta increases prostaglandin E2-stimulated adenosine 3',5'-cyclic monophosphate production in rabbit pigmented ciliary epithelium.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Interleukin-1; Isoproterenol; Kinetics; Lipopolysaccharides; Pigment Epithelium of Eye; Protein Synthesis Inhibitors; Rabbits; Stimulation, Chemical; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Up-Regulation; Vasoactive Intestinal Peptide | 1996 |
Dual role of prostaglandins (PGE2) in regulation of channel density and open probability of epithelial Na+ channels in frog skin (R. pipiens).
Topics: Animals; Biological Transport; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Ion Channel Gating; Models, Statistical; Rana pipiens; Skin; Sodium; Sodium Channels | 1997 |
Autocrine role of interleukin 1beta in altered responsiveness of atopic asthmatic sensitized airway smooth muscle.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Antibodies, Blocking; Asthma; Blotting, Northern; Cells, Cultured; Colforsin; Culture Techniques; Dinoprostone; Humans; Immunization, Passive; Interleukin-1; Isoproterenol; Muscle, Smooth; Polymerase Chain Reaction; Rabbits; Radioimmunoassay; Rats; Receptors, Interleukin-1; RNA, Messenger; Trachea | 1997 |
Effects of caffeine and theophylline on prostaglandin production by guinea-pig endometrium.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Caffeine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Endometrium; Female; Guinea Pigs; Prostaglandins; Ryanodine; Theophylline; Time Factors | 1997 |
alpha-Toxin-permeabilised rabbit fetal ductus arteriosus is more sensitive to Ca2+ than aorta or main pulmonary artery.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Aorta; Calcium; Colforsin; Cyclic AMP; Depression, Chemical; Dinoprostone; Ductus Arteriosus; Enzyme Activation; In Vitro Techniques; Muscle, Smooth, Vascular; Perfusion; Phosphodiesterase Inhibitors; Pulmonary Artery; Rabbits; Type C Phospholipases; Vasoconstriction | 1997 |
Functional interaction of the carboxylic acid group of agonists and the arginine residue of the seventh transmembrane domain of prostaglandin E receptor EP3 subtype.
Topics: Animals; Arginine; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Guanosine 5'-O-(3-Thiotriphosphate); Hydrogen Bonding; Mice; Mutagenesis, Site-Directed; Mutation; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Recombinant Proteins | 1997 |
Repression of inducible nitric oxide synthase and cyclooxygenase-2 by prostaglandin E2 and other cyclic AMP stimulants in J774 macrophages.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Dinoprostone; Enzyme Repression; Isoenzymes; Lipopolysaccharides; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases | 1997 |
1,25-dihydroxyvitamin D3 and agents that increase intracellular adenosine 3',5'-monophosphate synergistically inhibit fibroblast proliferation.
Topics: 24,25-Dihydroxyvitamin D 3; 3',5'-Cyclic-AMP Phosphodiesterases; 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Calcitriol; Cell Division; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Mice; Pentoxifylline; Phosphodiesterase Inhibitors; Theophylline | 1997 |
Regulation of superoxide production in human polymorphonuclear leukocytes (PMNs).
Topics: 1-Methyl-3-isobutylxanthine; Colforsin; Cyclic AMP; Cytochalasin B; Dinoprostone; Epinephrine; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides | 1997 |
Effect of IL-1 beta on responses of cultured human airway smooth muscle cells to bronchodilator agonists.
Topics: Adenylyl Cyclases; Binding, Competitive; Blotting, Western; Bronchodilator Agents; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Fungal Proteins; GTP-Binding Proteins; Humans; Interleukin-1; Iodine Radioisotopes; Isoproterenol; Magnetics; Muscle, Smooth; Oxytocics; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Cytokine; Saccharomyces cerevisiae Proteins; Trachea; Vesicular Transport Proteins | 1997 |
cAMP decreases steady-state levels of delta-opioid receptor mRNA in NG108-15 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Dinoprostone; Neuroblastoma; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptors, Opioid, delta; RNA, Messenger; Rolipram | 1997 |
Different effects of cyclic AMP and butyrate on eosinophilic differentiation, apoptosis and bcl-2 expression of a human eosinophilic leukemia cell line, EoL-1.
Topics: Apoptosis; Bucladesine; Butyrates; Butyric Acid; Cell Differentiation; Colforsin; Dinoprostone; Drug Combinations; Eosinophils; fas Receptor; Histamine Antagonists; Humans; Hypereosinophilic Syndrome; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 1996 |
Parathyroid hormone (1-34)-mediated interleukin-6 induction.
Topics: Becaplermin; Calcimycin; Colforsin; Dinoprostone; Drug Interactions; Gene Expression; Humans; Interleukin-1; Interleukin-6; Osteosarcoma; Plasmids; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Proto-Oncogene Proteins c-sis; Recombinant Fusion Proteins; Teriparatide; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1997 |
Interactions between interleukin-1 beta, nitric oxide and prostaglandin E2 in the rat ovary: effects on steroidogenesis.
Topics: Animals; Cells, Cultured; Colforsin; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; Enzyme Inhibitors; Female; Guanidines; Indomethacin; Interleukin-1; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Ovary; Rats; Rats, Wistar; Steroids | 1997 |
Two differential effects of cyclic adenosine 3',5'-monophosphate on IL-5 production by antigen-specific human T cell line.
Topics: Allergens; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Humans; Interleukin-2; Interleukin-5; Receptors, Antigen, T-Cell; RNA, Messenger; T-Lymphocytes | 1997 |
Prostaglandin E2 and tumor necrosis factor alpha cooperate to activate human dendritic cells: synergistic activation of interleukin 12 production.
Topics: Antigen Presentation; Bucladesine; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Dendritic Cells; Dinoprostone; Drug Synergism; Humans; Interleukin-12; Tumor Necrosis Factor-alpha | 1997 |
The C-terminal domain of the human EP4 receptor confers agonist-induced receptor desensitization in a receptor hybrid with the rat EP3beta receptor.
Topics: Alprostadil; Animals; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Humans; Ligands; Prostaglandins E, Synthetic; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Recombinant Fusion Proteins; Transfection | 1997 |
Osmotic regulation of Na+ transport across A6 epithelium: interactions with prostaglandin E2 and cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Biological Transport; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Activation; Epithelial Cells; Osmolar Concentration; Phosphodiesterase Inhibitors; Sodium Channels; Solutions; Water-Electrolyte Balance | 1997 |
Regulation of connexin43 expression and function by prostaglandin E2 (PGE2) and parathyroid hormone (PTH) in osteoblastic cells.
Topics: Animals; Cell Aggregation; Colforsin; Connexin 43; Cyclic AMP; Dactinomycin; Dinoprostone; Fluoresceins; Fluorescent Dyes; Gene Expression Regulation; Immunoblotting; Isoquinolines; Microinjections; Osteoblasts; Oxytocics; Parathyroid Hormone; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Signal Transduction; Time Factors; Tumor Cells, Cultured | 1998 |
A functional CFTR protein is required for mouse intestinal cAMP-, cGMP- and Ca(2+)-dependent HCO3- secretion.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bacterial Toxins; Bicarbonates; Calcium; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprostone; Duodenum; Enterotoxins; Escherichia coli Proteins; Gastrointestinal Hormones; Ileum; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Jejunum; Kinetics; Mice; Mice, Knockout; Microvilli; Natriuretic Peptides; Peptides; Vasoactive Intestinal Peptide | 1997 |
Regulation of the expression of aminopeptidase A, aminopeptidase N/CD13 and dipeptidylpeptidase IV/CD26 in renal carcinoma cells and renal tubular epithelial cells by cytokines and cAMP-increasing mediators.
Topics: Adjuvants, Immunologic; Aminopeptidases; Calcimycin; Carcinoma, Renal Cell; CD13 Antigens; Cholera Toxin; Colforsin; Cyclic AMP; Cytokines; Dinoprostone; Dipeptidyl Peptidase 4; Epithelial Cells; Glutamyl Aminopeptidase; Humans; Ionophores; Kidney Neoplasms; Kidney Tubules; Leucine; Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic | 1998 |
Synergistic activation of RLD-1 by agents triggering PKA and PKC dependent signalling.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; DNA-Binding Proteins; Drug Synergism; Enzyme Inhibitors; Genes, Reporter; Hydroxycholesterols; Indoles; Isoquinolines; Liver X Receptors; Maleimides; Orphan Nuclear Receptors; Protein Kinase C; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection | 1998 |
A selective type 4 phosphodiesterase inhibitor, T-440, modulates intracellular cyclic AMP level and interleukin-2 production of Jurkat cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adjuvants, Immunologic; Cell Membrane; Colforsin; Concanavalin A; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytosol; Dinoprostone; Humans; Interleukin-2; Jurkat Cells; Naphthalenes; Phosphodiesterase Inhibitors; Pyridones | 1998 |
The inhibition of DNA synthesis by prostaglandin E2 in human gingival fibroblasts is independent of the cyclic AMP-protein kinase A signal transduction pathway.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Gingiva; Humans; Isoquinolines; Male; Phosphodiesterase Inhibitors; Signal Transduction; Sulfonamides; Up-Regulation | 1998 |
B2 kinin receptor upregulation by cAMP is associated with BK-induced PGE2 production in rat mesangial cells.
Topics: Animals; Bradykinin; Calcium; Colforsin; Cyclic AMP; Cytosol; Dinoprostone; Dose-Response Relationship, Drug; Glomerular Mesangium; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Male; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Receptors, Bradykinin; RNA, Messenger; Second Messenger Systems; Signal Transduction; Up-Regulation | 1998 |
Inhibition of EGF-dependent mitogenesis by prostaglandin E2 in Syrian hamster embryo fibroblasts.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; Colforsin; Cricetinae; Dinoprostone; Dose-Response Relationship, Drug; Embryo, Mammalian; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; GTPase-Activating Proteins; Mesocricetus; Mitosis; Oxytocics; Phosphorylation; Proteins; Proto-Oncogene Mas; Proto-Oncogene Proteins c-raf | 1998 |
Regulation of prostaglandin G/H synthase-2 expression by interleukin-1 in human osteoblast-like cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Transformed; Colforsin; Cycloheximide; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Interleukin-1; Isoenzymes; Membrane Proteins; Osteoblasts; Osteosarcoma; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Synthesis Inhibitors; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
The cAMP transduction cascade mediates the prostaglandin E2 enhancement of the capsaicin-elicited current in rat sensory neurons: whole-cell and single-channel studies.
Topics: Animals; Capsaicin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Electric Conductivity; Ion Channel Gating; Ion Channels; Neurons, Afferent; Osmolar Concentration; Rats; Rats, Sprague-Dawley | 1998 |
cAMP analogues downregulate the expression of granulocyte macrophage colony-stimulating factor (GM-CSF) in human bone marrow stromal cells in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Bone Marrow Cells; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Down-Regulation; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; RNA, Messenger; Stromal Cells | 1998 |
Effects of LH, prostaglandin E2, 8-bromo-cyclic AMP and forskolin on progesterone secretion by pig luteal cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Size; Cells, Cultured; Colforsin; Corpus Luteum; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Estrus; Female; Luteinizing Hormone; Pregnancy; Progesterone; Stimulation, Chemical; Swine | 1998 |
Prostaglandin E2 stimulates IL-8 gene expression in human colonic epithelial cells by a posttranscriptional mechanism.
Topics: Adenocarcinoma; Bucladesine; Colforsin; Colon; Colonic Neoplasms; Cyclic AMP; Dexamethasone; Dinoprostone; Dose-Response Relationship, Immunologic; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Intracellular Fluid; Neoplasm Proteins; Protein Processing, Post-Translational; Receptors, Prostaglandin E; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Role of EP2 receptors and cAMP in prostaglandin E2 regulated expression of type I collagen alpha1, lysyl oxidase, and cyclooxygenase-1 genes in human embryo lung fibroblasts.
Topics: Alprostadil; Animals; Cell Line; Colforsin; Collagen; Cyclic AMP; Cyclooxygenase 1; Dinoprostone; Fibroblasts; Gene Expression Regulation; Humans; Isoenzymes; Lung; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Protein-Lysine 6-Oxidase; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; Transforming Growth Factor beta | 1998 |
Assessment of rapid morphological changes associated with elevated cAMP levels in human orbital fibroblasts.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Abdomen; Bucladesine; Cell Size; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Dermis; Dinoprostone; Dose-Response Relationship, Drug; Fibroblasts; Graves Disease; Humans; Isoenzymes; Lymphokines; Membrane Proteins; Orbit; Prostaglandin-Endoperoxide Synthases; Time Factors | 1998 |
Neurotensin enhances agonist-induced cAMP accumulation in PC3 cells via Ca2+ -dependent adenylyl cyclase(s).
Topics: Adenylyl Cyclases; Calcium; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Egtazic Acid; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Humans; Ionomycin; Isoproterenol; Male; Neurotensin; Prostatic Neoplasms; Thapsigargin; Tumor Cells, Cultured; Uridine Triphosphate | 1998 |
Ethanol dissociates hormone-stimulated cAMP production from inhibition of TNF-alpha production in rat Kupffer cells.
Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Separation; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Ethanol; GTP-Binding Proteins; Hormones; Kupffer Cells; Male; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Purinergic P1; Tumor Necrosis Factor-alpha | 1999 |
Activation of an adenosine 3',5'-cyclic monophosphate-dependent Cl- conductance in response to neurohormonal stimuli in mouse endometrial epithelial cells: the role of cystic fibrosis transmembrane conductance regulator.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprost; Dinoprostone; Electric Conductivity; Endometrium; Enzyme Activation; Enzyme Inhibitors; Epinephrine; Epithelial Cells; Female; Mice; Mice, Inbred ICR; Patch-Clamp Techniques | 1999 |
Theophylline-induced B-CLL apoptosis is partly dependent on cyclic AMP production but independent of CD38 expression and endogenous IL-10 production.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Apoptosis; B-Lymphocytes; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Humans; Immunophenotyping; Interleukin-10; Leukemia, Lymphocytic, Chronic, B-Cell; Membrane Glycoproteins; NAD+ Nucleosidase; Theophylline; Thionucleotides | 1999 |
Downregulation of JAK3 protein levels in T lymphocytes by prostaglandin E2 and other cyclic adenosine monophosphate-elevating agents: impact on interleukin-2 receptor signaling pathway.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Induction; Gene Expression Regulation; Humans; Interleukin-2; Janus Kinase 3; Phorbol 12,13-Dibutyrate; Protein-Tyrosine Kinases; Receptors, Interleukin-2; Recombinant Proteins; Second Messenger Systems; T-Lymphocytes | 1999 |
Inhibition of phospholipase A2-mediated arachidonic acid release by cyclic AMP defines a negative feedback loop for P2Y receptor activation in Madin-Darby canine kidney D1 cells.
Topics: Animals; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Dogs; Enzyme Activation; Epinephrine; Feedback; Isoproterenol; Kidney; Phospholipase D; Phospholipases A; Phospholipases A2; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Uridine Triphosphate | 1999 |
TGF-alpha reduces bradykinin-stimulated ion transport and prostaglandin release in human colonic epithelial cells.
Topics: Arachidonic Acid; Bradykinin; Carbachol; Cell Line; Chlorides; Colforsin; Colon; Cyclic AMP; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Humans; Intestinal Mucosa; Isoenzymes; Kinetics; Membrane Potentials; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Time Factors; Transforming Growth Factor alpha | 1999 |
Combined effects of caffeine and prostaglandin E2 on the proliferation of osteoblast-like cells (UMR106-01).
Topics: 1-Methyl-3-isobutylxanthine; Animals; Caffeine; Cell Division; Cell Line; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Indomethacin; Osteoblasts; Periodontitis; Phosphodiesterase Inhibitors; Rats; Risk Factors; Time Factors | 1999 |
Differential effect of TPA on PGE2 and cicaprost-induced cAMP synthesis in UMR-106 cells.
Topics: Animals; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Sodium Fluoride; Tetradecanoylphorbol Acetate; Time Factors | 1999 |
Intracellular measurement of prostaglandin E2: effect of anti-inflammatory drugs on cyclooxygenase activity and prostanoid expression.
Topics: 3T3 Cells; Adenylyl Cyclases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Cell Line; Colforsin; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Enzyme Induction; Glucocorticoids; Humans; Intracellular Fluid; Ionophores; Lipopolysaccharides; Mice; Monocytes; Prostaglandin-Endoperoxide Synthases; Prostaglandins | 1999 |
Prostaglandin E2 regulates vitamin D receptor expression, vitamin D-24-hydroxylase activity and cell proliferation in an adherent human myeloid leukemia cell line (Ad-HL60).
Topics: 24,25-Dihydroxyvitamin D 3; Antigens, CD; Calcitriol; Cell Division; Colforsin; Cyclic AMP; Cytochrome P-450 Enzyme System; Dinoprostone; Flow Cytometry; HL-60 Cells; Humans; Phenotype; Receptors, Calcitriol; Steroid Hydroxylases; Tetradecanoylphorbol Acetate; Vitamin D3 24-Hydroxylase | 1999 |
Effects of dehydroepiandrosterone on mitogen-activated protein kinase in human aortic smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cells, Cultured; Colforsin; Cyclic AMP; Dehydroepiandrosterone; Dinoprostone; Enzyme Activation; Growth Substances; Humans; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular | 1999 |
Roles of prostaglandin E receptors in mesangial cells under high-glucose conditions.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Anti-Ulcer Agents; Blotting, Northern; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Gene Expression; Glomerular Mesangium; Glucose; Male; Menstruation-Inducing Agents; Phosphodiesterase Inhibitors; Prostaglandins E, Synthetic; Rats; Rats, Inbred WKY; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; RNA, Messenger; Thymidine; Tritium | 1999 |
PGE(2)-mediated inhibition of T cell p59(fyn) is independent of cAMP.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Antibodies; CD3 Complex; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Inhibitors; Male; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Rats; Rats, Sprague-Dawley; T-Lymphocytes | 1999 |
Dinoprostone potentiates cytokines and lipopolysaccharides inducing nitric oxide production in cultured rat hepatocytes.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cytokines; Dinoprostone; Drug Synergism; Indomethacin; Lipopolysaccharides; Liver; Male; Nitric Oxide; Rats; Rats, Wistar | 1999 |
Selective activation of the prostanoid EP(3) receptor reduces myocardial infarct size in rodents.
Topics: Animals; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Intracellular Membranes; Mice; Myocardial Infarction; Myocardial Ischemia; Rabbits; Rats; Rats, Wistar; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Transfection; Troponin T | 1999 |
Impaired duodenal bicarbonate secretion and mucosal integrity in mice lacking prostaglandin E-receptor subtype EP(3).
Topics: Animals; Bicarbonates; Colforsin; Dinoprostone; Duodenal Ulcer; Duodenum; Hydrochloric Acid; Intestinal Mucosa; Mice; Mice, Knockout; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP3 Subtype | 1999 |
Age-related effects of oxidative metabolism and cyclic AMP signaling on neutrophil apoptosis.
Topics: Adult; Aged; Aged, 80 and over; Aging; Antioxidants; Apoptosis; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Female; Humans; In Vitro Techniques; Male; Neutrophils; Oxidation-Reduction; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase | 1999 |
Regulation of connective tissue growth factor expression by prostaglandin E(2).
Topics: Blotting, Western; Cells, Cultured; Colforsin; Collagen; Connective Tissue Growth Factor; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dinoprostone; Fibroblasts; Gene Expression Regulation; Growth Substances; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Lung; Protein Synthesis Inhibitors; RNA, Messenger; Transcription, Genetic; Transfection; Transforming Growth Factor beta | 1999 |
Role of cell contractions in cAMP-induced cardiomyocyte atrial natriuretic peptide release.
Topics: Animals; Atrial Natriuretic Factor; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cytosol; Dinoprostone; Myocardial Contraction; Myocardium; Osmolar Concentration; Rats; Rats, Wistar | 2000 |
Prostaglandin E2 stimulates AP-1-mediated CD14 expression in mouse macrophages via cyclic AMP-dependent protein kinase A.
Topics: Animals; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation; Interleukin-1; Interleukin-6; Isoquinolines; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Oligonucleotides, Antisense; Prostaglandins; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Sulfonamides; Transcription Factor AP-1; Transcription, Genetic | 2000 |
The induction of cyclooxygenase-2 in IL-1beta-treated endothelial cells is inhibited by prostaglandin E2 through cAMP.
Topics: 6-Ketoprostaglandin F1 alpha; Colforsin; Cyclic AMP; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Drug Antagonism; Drug Interactions; Endothelium, Vascular; Enzyme Induction; Humans; Interleukin-1; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Umbilical Veins | 1999 |
Characterization of ep prostanoid receptor subtypes in primary cultures of bovine ciliary epithelial cells by immunofluorescent microscopy and functional studies.
Topics: Animals; Cattle; Cells, Cultured; Ciliary Body; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Fluorescent Antibody Technique, Indirect; Inositol Phosphates; Isoproterenol; Microscopy, Fluorescence; Pigment Epithelium of Eye; Receptors, Prostaglandin E; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2000 |
Effects of latanoprost on tyrosinase activity and mitotic index of cultured melanoma lines.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Enzyme Induction; Enzyme-Linked Immunosorbent Assay; Humans; Intraocular Pressure; Latanoprost; Melanoma; Mice; Mitotic Index; Monophenol Monooxygenase; Pigmentation; Prostaglandins F, Synthetic; Skin Neoplasms; Stimulation, Chemical; Time Factors; Tumor Cells, Cultured; Uveal Neoplasms | 2000 |
Murine myeloid progenitor responses to GM-CSF and eosinophil precursor responses to IL-5 represent distinct targets for downmodulation by prostaglandin E(2).
Topics: Animals; Bone Marrow Cells; Bucladesine; Cell Differentiation; Cells, Cultured; Colforsin; Colony-Forming Units Assay; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Eosinophils; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Interleukin-5; Male; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Mice, Inbred Strains; Prostaglandin D2; Rolipram | 2000 |
Androgen control of cyclooxygenase expression in the rat epididymis.
Topics: Animals; Bradykinin; Colforsin; Cyclic AMP; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Epididymis; Epithelium; Gene Expression Regulation, Enzymologic; Isoenzymes; Male; Membrane Proteins; Orchiectomy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Testosterone | 2000 |
Prostaglandin E2-induced sensitization of bradykinin-evoked responses in rat dorsal root ganglion neurons is mediated by cAMP-dependent protein kinase A.
Topics: Adenylyl Cyclases; Animals; Bradykinin; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Ganglia, Spinal; Inositol 1,4,5-Trisphosphate; Isoquinolines; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Substance P; Sulfonamides; Tritium | 2000 |
A primary culture of guinea pig gallbladder epithelial cells that is responsive to secretagogues.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Anions; Biological Transport; Calcium; Calcium Channel Blockers; Cells, Cultured; Cholecystokinin; Colforsin; Cyclic AMP; Dinoprostone; Epithelial Cells; Gallbladder; Gastrointestinal Agents; Guinea Pigs; Histamine; Ionomycin; Ionophores; Male; ortho-Aminobenzoates; Secretin; Vasoactive Intestinal Peptide | 2000 |
Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth-muscle cells. Modulation by cyclic adenosine monophosphate.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Bucladesine; Cells, Cultured; Chemokine CCL5; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Dinoprostone; Dose-Response Relationship, Drug; Humans; Interleukin-6; Muscle, Smooth; NF-kappa B; Nitriles; Phosphodiesterase Inhibitors; RNA, Messenger; Time Factors; Trachea; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2000 |
Prostaglandin receptors and role of G protein-activated pathways on corpora lutea of pseudopregnant rabbit in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Analysis of Variance; Animals; Colforsin; Corpus Luteum; Culture Techniques; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Imipramine; Luteal Phase; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Progesterone; Protein Kinase C; Pseudopregnancy; Rabbits; Receptors, Prostaglandin; Receptors, Prostaglandin E; Signal Transduction; Statistics, Nonparametric; Staurosporine; Type C Phospholipases | 2001 |
Prostaglandins E2 and I2 downregulate tumor necrosis factor alpha-induced intercellular adhesion molecule-1 expression in human oral gingival epithelial cells.
Topics: Acetates; Adult; Alprostadil; Analysis of Variance; Benzhydryl Compounds; Bucladesine; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Epithelial Cells; Epoprostenol; Gene Expression Regulation; Gingiva; Humans; Intercellular Adhesion Molecule-1; Receptors, Prostaglandin E; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Tumor Necrosis Factor-alpha | 2000 |
Regulation of osteoprotegerin secretion from primary cultures of human bone marrow stromal cells.
Topics: Bone Marrow Cells; Cells, Cultured; Colforsin; Dexamethasone; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Glycoproteins; Humans; Interleukin-1; Osteoprotegerin; Phorbol 12,13-Dibutyrate; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Stromal Cells; Tumor Necrosis Factor-alpha | 2001 |
Cloning and function of the rat colonic epithelial K+ channel KVLQT1.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Barium; Carbachol; Cardiotonic Agents; Cloning, Molecular; Colforsin; Colon; Cyclic AMP; Dinoprostone; Humans; In Vitro Techniques; Intestinal Mucosa; KCNQ Potassium Channels; KCNQ1 Potassium Channel; Male; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Tetraethylammonium; Xenopus laevis | 2001 |
Characterization of adenylyl cyclases in cultured human granulosa cells.
Topics: Adenylyl Cyclases; Calcimycin; Calcium; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Inhibitors; Female; Granulosa Cells; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Isoenzymes; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 2001 |
Mechanisms involved in prostaglandin-induced increase in bone resorption in neonatal mouse calvaria.
Topics: Alprostadil; Animals; Animals, Newborn; Bone Resorption; Colforsin; Culture Techniques; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Mice; Misoprostol; Prostaglandins; Prostaglandins F, Synthetic; Skull | 2001 |
Prostaglandin receptor subtypes, EP3C and EP4, mediate the prostaglandin E2-induced cAMP production and sensitization of sensory neurons.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Embryo, Mammalian; Ganglia, Spinal; Gene Expression Regulation; Neurons, Afferent; Oligodeoxyribonucleotides, Antisense; Polymerase Chain Reaction; Rats; Receptors, Epoprostenol; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger; Transcription, Genetic | 2001 |
ERK activation and mitogenesis in human airway smooth muscle cells.
Topics: Blood Proteins; Bronchi; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cyclin D1; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mitogens; Muscle, Smooth; Oligonucleotides, Antisense; Phosphorylation; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Ribosomal Protein S6 Kinases; Signal Transduction; Thrombin | 2001 |
Requirement of additional adenylate cyclase activation for the inhibition of human eosinophil degranulation by phosphodiesterase IV inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Adult; Albuterol; Benzamides; Cell Degranulation; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Eosinophil Peroxidase; Eosinophils; Histamine; Humans; Nitriles; Peroxidases; Phosphodiesterase Inhibitors; Pyridines; Rolipram; Superoxides; Theophylline | 2001 |
Involvement of the nuclear orphan receptor NURR1 in the regulation of corticotropin-releasing hormone expression and actions in human inflammatory arthritis.
Topics: Arthritis, Rheumatoid; Blotting, Northern; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Culture Media, Conditioned; Dinoprostone; DNA Primers; DNA-Binding Proteins; Humans; Immunoenzyme Techniques; Interleukin-1; Knee Joint; Nerve Tissue Proteins; Nuclear Receptor Subfamily 4, Group A, Member 1; Nuclear Receptor Subfamily 4, Group A, Member 2; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synovial Membrane; Transcription Factors; Transfection; Tumor Necrosis Factor-alpha; Up-Regulation | 2001 |
Regulation of prostacyclin and prostaglandin E(2) receptor mediated responses in adult rat dorsal root ganglion cells, in vitro.
Topics: Adenylyl Cyclases; Aging; Alprostadil; Animals; Antineoplastic Agents; Cell Count; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Down-Regulation; Enzyme Activation; Epoprostenol; Ganglia, Spinal; Iloprost; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, Epoprostenol; Receptors, Prostaglandin | 2001 |
Leukemia inhibitory factor antagonizes gonadotropin induced-testosterone synthesis in cultured porcine leydig cells: sites of action.
Topics: Androstenedione; Animals; Cells, Cultured; Cholera Toxin; Cholesterol; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dehydroepiandrosterone; Dinoprostone; Gene Expression; Growth Inhibitors; Hydroxycholesterols; Interleukin-6; Leukemia Inhibitory Factor; Leukemia Inhibitory Factor Receptor alpha Subunit; Leydig Cells; Luteinizing Hormone; Lymphokines; Male; Mitochondria; Phosphoproteins; Pregnenolone; Receptors, Cytokine; Receptors, OSM-LIF; RNA, Messenger; Swine; Testis; Testosterone | 2001 |
Mechanisms of regulation of agonist efficacy at the 5-HT(1A) receptor by phospholipid-derived signaling components.
Topics: Adenylyl Cyclases; Animals; Arachidonic Acid; CHO Cells; Cholera Toxin; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Enzyme Activation; Humans; Melitten; Phorbol Esters; Phospholipases A; Phospholipids; Protein Kinase C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Signal Transduction; Transfection; Type C Phospholipases | 2001 |
Hormonal control of insulin-like growth factor I gene transcription in human osteoblasts: dual actions of cAMP-dependent protein kinase on CCAAT/enhancer-binding protein delta.
Topics: Animals; CCAAT-Enhancer-Binding Protein-delta; CCAAT-Enhancer-Binding Proteins; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Humans; Insulin-Like Growth Factor I; Osteoblasts; Parathyroid Hormone; Rats; Transcription Factors; Transcription, Genetic | 2001 |
Suppression of T-cell responsiveness by inducible cAMP early repressor (ICER).
Topics: Animals; Cell Division; Chemokines; Colforsin; Cyclic AMP; Cyclic AMP Response Element Modulator; Cytokines; Dinoprostone; DNA-Binding Proteins; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-2; Ionomycin; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Promoter Regions, Genetic; Repressor Proteins; Second Messenger Systems; Spleen; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells; Transcription, Genetic | 2001 |
Stimulatory and synergistic effects of luteinising hormone and insulin like growth factor 1 on the secretion of vascular endothelial growth factor and progesterone of cultured bovine granulosa cells.
Topics: Animals; Cattle; Cells, Cultured; Colforsin; Dinoprost; Dinoprostone; Drug Synergism; Endothelial Growth Factors; Female; Fibroblast Growth Factor 2; Granulosa Cells; Growth Hormone; Hydrocortisone; Insulin-Like Growth Factor I; Ionophores; Luteinizing Hormone; Lymphokines; Progesterone; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Molecular cloning and functional characterization of the canine prostaglandin E2 receptor EP4 subtype.
Topics: Amino Acid Sequence; Animals; Base Sequence; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Dogs; Humans; Molecular Sequence Data; Prostaglandins A; Protein Binding; Protein Isoforms; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Recombinant Proteins; Sequence Alignment; Signal Transduction; Tissue Distribution | 2001 |
EP1 and EP4 receptors mediate exocytosis evoked by prostaglandin E(2) in guinea-pig antral mucous cells.
Topics: Animals; Antineoplastic Agents; Bucladesine; Calcium; Cinnamates; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Inhibitors; Exocytosis; Gastric Mucosa; Guinea Pigs; Isoquinolines; Male; Microscopy, Video; Pyloric Antrum; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfonamides | 2001 |
PGE(2) activation of apical membrane Cl(-) channels in A6 epithelia: impedance analysis.
Topics: Amiloride; Animals; Cell Membrane; Cell Polarity; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Dinoprostone; Electric Conductivity; Electric Impedance; Epithelial Cells; Ion Transport | 2001 |
Prostaglandin E2 activates the ciliary beat frequency of cultured human nasal mucosa via the second messenger cyclic adenosine monophosphate.
Topics: Adult; Aged; Cells, Cultured; Cilia; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Epithelial Cells; Female; Humans; In Vitro Techniques; Male; Middle Aged; Nasal Mucosa; Second Messenger Systems; Signal Transduction | 2001 |
Role of lysophosphatidylcholine in the desensitization of beta-adrenergic receptors by Ca(2+) sensitization in tracheal smooth muscle.
Topics: Adenylate Cyclase Toxin; Adrenergic beta-Agonists; Amides; Animals; Bucladesine; Calcium; Cholera Toxin; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Indoles; Isoproterenol; Lysophosphatidylcholines; Male; Maleimides; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Pyridines; Receptors, Adrenergic, beta; rho GTP-Binding Proteins; Spectrometry, Fluorescence; Theophylline; Trachea; Virulence Factors, Bordetella | 2001 |
Prostaglandin E(2) inhibits fibroblast chemotaxis.
Topics: Adrenergic beta-Agonists; Animals; Bronchi; Bucladesine; Cattle; Cell Line; Chemotactic Factors; Chemotaxis; Colforsin; Culture Media, Conditioned; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Fetus; Fibroblasts; Fibronectins; Humans; Indomethacin; Isoproterenol; Oxytocics; Respiratory Mucosa; Substance P; Vasoactive Intestinal Peptide; Vasodilator Agents | 2001 |
Inhibition of epithelial chloride secretion by butyrate: role of reduced adenylyl cyclase expression and activity.
Topics: 1-Methyl-3-isobutylxanthine; Acetates; Adenylyl Cyclases; Butyrates; Calcium; Cell Line; Chlorides; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Humans; Intestinal Mucosa; Phosphodiesterase Inhibitors; Propionates; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Time Factors | 2001 |
Histamine increases the expression of LOX-1 via H2 receptor in human monocytic THP-1 cells.
Topics: Bucladesine; Cell Differentiation; Colforsin; CREB-Binding Protein; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytokines; Dinoprostone; Enzyme Inhibitors; Gene Expression Regulation; Histamine; Humans; Isoquinolines; Macrophages; Monocytes; Nuclear Proteins; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, LDL; Receptors, Oxidized LDL; RNA, Messenger; Scavenger Receptors, Class E; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Trans-Activators; Tumor Cells, Cultured; Up-Regulation | 2001 |
Regulation of pacemaker frequency in the murine gastric antrum.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Colforsin; Dinoprostone; Electrophysiology; Female; Male; Mice; Mice, Inbred BALB C; Periodicity; Pyloric Antrum; Receptors, Prostaglandin E | 2002 |
Stimulation of chloride secretion by baicalein in isolated rat distal colon.
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Atropine; Calcium; Carbachol; Chlorides; Colforsin; Colon; Cyclic AMP; Dinoprostone; Electric Conductivity; Female; Flavanones; Flavonoids; Indomethacin; Intestinal Mucosa; Male; Muscarinic Antagonists; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Thapsigargin | 2002 |
Secretory modulation of basolateral membrane inwardly rectified K(+) channel in guinea pig distal colonic crypts.
Topics: Animals; Carbachol; Chlorides; Cholinergic Agents; Colforsin; Colon; Dinoprostone; Epinephrine; Guinea Pigs; Ion Channel Gating; Kinetics; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium; Potassium Channels, Inwardly Rectifying; Sodium; Sympathomimetics | 2002 |
Sensitization to mechanical stimulation by inflammatory mediators and by mild burn in canine visceral nociceptors in vitro.
Topics: Animals; Bradykinin; Burns; Colforsin; Dinoprostone; Dogs; Histamine; Hot Temperature; Inflammation Mediators; Nociceptors; Phorbol 12,13-Dibutyrate; Physical Stimulation; Protons; Viscera | 2002 |
Vector-averaged gravity regulates gene expression of receptor activator of NF-kappaB (RANK) ligand and osteoprotegerin in bone marrow stromal cells via cyclic AMP/protein kinase A pathway.
Topics: Animals; Bone Marrow Cells; Bucladesine; Carrier Proteins; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Gene Expression; Genes, Reporter; Glycoproteins; Gravitation; Isoquinolines; Luciferases; Membrane Glycoproteins; Osteoprotegerin; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; RNA, Messenger; Stromal Cells; Sulfonamides | 2002 |
Prostaglandin E(2) inhibits IL-18-induced ICAM-1 and B7.2 expression through EP2/EP4 receptors in human peripheral blood mononuclear cells.
Topics: Antibodies; Antigens, CD; B7-1 Antigen; B7-2 Antigen; Blood; Bucladesine; Cells, Cultured; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Humans; Intercellular Adhesion Molecule-1; Interleukin-18; Kinetics; Membrane Glycoproteins; Monocytes; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype | 2002 |
PGE(2) increases release of substance P from renal sensory nerves by activating the cAMP-PKA transduction cascade.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Animals; Bradykinin; Calcitonin Gene-Related Peptide; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Kidney Pelvis; Male; Neurons, Afferent; Peripheral Nerves; Pressure; Rats; Rats, Sprague-Dawley; Signal Transduction; Substance P | 2002 |
Substance P-evoked Cl(-) secretion in guinea pig distal colonic epithelia: interaction with PGE(2).
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Chlorides; Colforsin; Colon; Dinoprostone; Drug Synergism; Electric Conductivity; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Intestinal Mucosa; Male; Piroxicam; Substance P; Tetrodotoxin | 2002 |
Prostaglandin E(2) inhibits replication of HIV-1 in macrophages through activation of protein kinase A.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Viral; HIV-1; Humans; Kinetics; Macrophages; Misoprostol; Monocytes; Promoter Regions, Genetic; Receptors, CCR5; RNA, Viral; Virus Replication | 2002 |
Peripheral group II metabotropic glutamate receptors (mGluR2/3) regulate prostaglandin E2-mediated sensitization of capsaicin responses and thermal nociception.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Capsaicin; Colforsin; Dinoprostone; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GTP-Binding Protein alpha Subunits, Gi-Go; Hot Temperature; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Neurons, Afferent; Pain Measurement; Pertussis Toxin; Phosphorylation; Proline; Receptors, Drug; Receptors, Metabotropic Glutamate; Virulence Factors, Bordetella | 2002 |
Neuroprotective effects of prostaglandin E2 or cAMP against microglial and neuronal free radical mediated toxicity associated with inflammation.
Topics: Actins; Analysis of Variance; Animals; Apoptosis; Blotting, Northern; Blotting, Western; Brain; Caspase 3; Caspases; Cell Death; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Drug Interactions; Fetus; Fluoresceins; Free Radicals; Immunohistochemistry; In Situ Nick-End Labeling; Lipopolysaccharides; Mice; Mice, Inbred ICR; Microglia; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Inhibition of cyclooxygenase-2: effects on renin secretion and expression in fetal lambs.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Blood Gas Analysis; Cells, Cultured; Colforsin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Gene Expression Regulation, Developmental; Heart Rate; Isoenzymes; Isoproterenol; Kidney Cortex; Nitrobenzenes; Phosphodiesterase Inhibitors; Pregnancy; Prostaglandin-Endoperoxide Synthases; Renin; Renin-Angiotensin System; RNA, Messenger; Sheep, Domestic; Sulfonamides | 2003 |
Stra13, a prostaglandin E2-induced gene, regulates the cellular redox state of podocytes.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Colforsin; Dinoprostone; DNA, Antisense; Gene Expression Regulation; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Homeodomain Proteins; Kidney Glomerulus; Membrane Proteins; Mice; NADPH Oxidases; Oxidation-Reduction; Reactive Oxygen Species; RNA, Messenger; Tretinoin | 2003 |
Ca2+ transient evoked by chemical stimulation is enhanced by PGE2 in vagal sensory neurons: role of cAMP/PKA signaling pathway.
Topics: Adenosine Triphosphate; Animals; Calcium; Capsaicin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Male; Neurons, Afferent; Nodose Ganglion; Potassium Chloride; Rats; Rats, Sprague-Dawley; Signal Transduction; Stimulation, Chemical; Thionucleotides | 2003 |
Induction of cyclooxygenase-2 by lipopolysaccharide in canine tracheal smooth muscle cells: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kappaB pathways.
Topics: Animals; Calcium; Cells, Cultured; Cholera Toxin; Colforsin; Cyclooxygenase 2; Dinoprostone; Dogs; Enzyme Inhibitors; Female; Isoenzymes; Lipopolysaccharides; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphoinositide-3 Kinase Inhibitors; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Signal Transduction; Trachea | 2003 |
TNF-[alpha] modulates murine tracheal rings responsiveness to G-protein-coupled receptor agonists and KCl.
Topics: Animals; Antigens, CD; Carbachol; Cholera Toxin; Colforsin; Dinoprostone; Drug Synergism; Female; In Vitro Techniques; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Pertussis Toxin; Potassium Chloride; Receptors, G-Protein-Coupled; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Trachea; Tumor Necrosis Factor-alpha | 2003 |
Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation.
Topics: Cell Differentiation; Colforsin; Cyclic AMP; Dinoprostone; Fibroblasts; Humans; Receptors, Prostaglandin E | 2003 |
A multi-tyrosinated sst1/2 receptor preferring somatostatin agonist inhibits reflex and immune-mediated secretion in the guinea pig colon.
Topics: Animals; Chlorides; Colforsin; Colon; Cyclic AMP; Dimaprit; Dinoprostone; Electrophysiology; Guinea Pigs; Intestinal Mucosa; Male; Receptors, Histamine H2; Receptors, Somatostatin; Reflex; Serotonin; Somatostatin; Tetrodotoxin; Tyrosine | 2003 |
Prostaglandin E2 stimulates bone sialoprotein (BSP) expression through cAMP and fibroblast growth factor 2 response elements in the proximal promoter of the rat BSP gene.
Topics: Animals; Base Sequence; Cell Line; Colforsin; Cyclic AMP Response Element-Binding Protein; Dinoprostone; Electrophoretic Mobility Shift Assay; Fibroblast Growth Factor 2; Gene Deletion; Gene Expression; Integrin-Binding Sialoprotein; Luciferases; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sialoglycoproteins; Transcription, Genetic; Transfection | 2003 |
Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Endothelial Growth Factors; Endothelium, Vascular; Fibroblast Growth Factor 2; Humans; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Lymphokines; Microcirculation; Neovascularization, Physiologic; Phosphodiesterase Inhibitors; Promoter Regions, Genetic; Receptors, CXCR4; Sp1 Transcription Factor; Transcriptional Activation; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
The prostaglandin E2 analogue sulprostone antagonizes vasopressin-induced antidiuresis through activation of Rho.
Topics: Actins; Animals; Aquaporin 2; Aquaporins; Biological Transport; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cytoplasmic Vesicles; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Kidney Medulla; Microscopy, Fluorescence; Models, Molecular; Neurophysins; Prostaglandin Antagonists; Protein Precursors; Rats; Receptors, Prostaglandin E; Receptors, Vasopressin; rho GTP-Binding Proteins; Signal Transduction; Vasopressins | 2003 |
Cyclic AMP increases endogenous granulocyte colony-stimulating factor formation in monocytes and THP-1 macrophages despite attenuated TNF-alpha formation.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Bucladesine; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Female; Granulocyte Colony-Stimulating Factor; Humans; In Vitro Techniques; Lipopolysaccharides; Macrophages; Monocytes; Naphthyridines; Pentoxifylline; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Tumor Necrosis Factor-alpha; Up-Regulation | 2003 |
Ammonium effects on colonic Cl- secretion: anomalous mole fraction behavior.
Topics: Cell Line; Chlorides; Chlorine; Colforsin; Colon; Dinoprostone; Epithelium; Humans; Hydrogen-Ion Concentration; Potassium; Potassium Channels; Quaternary Ammonium Compounds; Radioisotopes; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical | 2004 |
Role of prostaglandin E2 receptors in migration of murine and human breast cancer cells.
Topics: Alprostadil; Animals; Breast Neoplasms; Carcinoma; Cell Movement; Colforsin; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Indoles; Isoenzymes; Mammary Neoplasms, Experimental; Membrane Proteins; Mice; Neoplasm Invasiveness; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Tumor Cells, Cultured; Up-Regulation; Xanthenes; Xanthones | 2003 |
Prostaglandin E2 is an enhancer of interleukin-1beta-induced expression of membrane-associated prostaglandin E synthase in rheumatoid synovial fibroblasts.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Dinoprostone; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Interleukin-1; Intramolecular Oxidoreductases; Isoenzymes; Lactones; Membrane Proteins; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger; Sulfones; Synovial Membrane | 2003 |
Prostaglandin E2 induces upregulation of Na+ transport across Xenopus lung epithelium.
Topics: Animals; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Epithelium; Epoprostenol; Female; Lung; Sodium Channels; Up-Regulation; Xenopus laevis | 2004 |
Short-term regulation of basolateral organic anion uptake in proximal tubular opossum kidney cells: prostaglandin E2 acts via receptor-mediated activation of protein kinase A.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Glutarates; Imines; Kidney Tubules, Proximal; Opossums; Receptors, Prostaglandin E; Signal Transduction; Time Factors | 2003 |
Interleukin-1beta, transforming growth factor-beta1, and bradykinin attenuate cyclic AMP production by human pulmonary artery smooth muscle cells in response to prostacyclin analogues and prostaglandin E2 by cyclooxygenase-2 induction and downregulation o
Topics: Adenylyl Cyclases; Adult; Arachidonic Acid; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Induction; Epoprostenol; Gene Expression Regulation, Enzymologic; Growth Substances; Humans; Interleukin-1; Isoenzymes; Isoproterenol; Membrane Proteins; Muscle, Smooth, Vascular; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pulmonary Artery; RNA, Messenger; Sulfonamides; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Impact of cAMP on the T-cell response to type II collagen.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antigen-Presenting Cells; Arthritis, Experimental; Arthritis, Rheumatoid; Cells, Cultured; Cholera Toxin; Colforsin; Collagen Type II; Cyclic AMP; Dinoprostone; Enzyme Activation; Interferon-gamma; Interleukin-4; Interleukin-5; Male; Mice; Mice, Inbred DBA; Models, Animal; Phosphodiesterase Inhibitors; Rolipram; Second Messenger Systems; T-Lymphocytes | 2004 |
Prostaglandin E2 induces degranulation-independent production of vascular endothelial growth factor by human mast cells.
Topics: Albuterol; Cell Degranulation; Cell Line, Tumor; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Estradiol; Fetal Blood; Humans; Immunoglobulin E; Interleukin-1; Interleukin-6; Mast Cells; Pentoxifylline; Protein Isoforms; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor B; Vascular Endothelial Growth Factor C; Vascular Endothelial Growth Factor D | 2004 |
The time-course of cyclic AMP signaling is critical for leukemia U-937 cell differentiation.
Topics: Calcium; Cell Differentiation; Cell Division; Colforsin; Complement C5a; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Humans; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Receptors, Histamine H2; Receptors, Prostaglandin E; Recombinant Proteins; Signal Transduction; Thiazoles; Time Factors; U937 Cells | 2004 |
Regulatory effects of interleukin-1beta and prostaglandin E2 on expression of receptor activator of nuclear factor-kappaB ligand in human periodontal ligament cells.
Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Bucladesine; Carrier Proteins; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Dinoprostone; Female; Humans; Interleukin-1; Ligands; Male; Membrane Glycoproteins; NF-kappa B; Osteoclasts; Periodontal Ligament; Phosphodiesterase Inhibitors; Protein Kinase C; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger | 2004 |
cAMP-elevating agents and adenylyl cyclase overexpression promote an antifibrotic phenotype in pulmonary fibroblasts.
Topics: Adenylyl Cyclases; Animals; Cell Division; Cell Line; Colforsin; Collagen; Cyclic AMP; Dinoprostone; Extracellular Matrix; Extracellular Matrix Proteins; Fibroblasts; Humans; Isoenzymes; Lung; Mice; Phenotype; Pulmonary Fibrosis | 2004 |
Increased sensitivity of asthmatic airway smooth muscle cells to prostaglandin E2 might be mediated by increased numbers of E-prostanoid receptors.
Topics: Asthma; Cell Division; Cells, Cultured; Colforsin; Dinoprostone; Epoprostenol; Humans; Lung; Muscle, Smooth; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype | 2004 |
PGE2 induces IL-1beta gene expression in mouse osteoblasts through a cAMP-PKA signaling pathway.
Topics: Adenylyl Cyclase Inhibitors; Animals; Animals, Newborn; Blotting, Northern; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dideoxyadenosine; Dinoprostone; Enzyme Inhibitors; Gene Expression; Interleukin-1; Mice; Mice, Inbred BALB C; Osteoblasts; Plasmids; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 2004 |
Inhibition of Rho modulates cytokine-induced prostaglandin E2 formation in renal mesangial cells.
Topics: Animals; Blotting, Western; Cells, Cultured; Colforsin; Dinoprostone; Glomerular Mesangium; Interleukin-1; Phospholipases A; Phospholipases A2; Rats; rho GTP-Binding Proteins | 2004 |
Prostaglandin E2 induces IL-23 production in bone marrow-derived dendritic cells.
Topics: Alprostadil; Animals; Arthritis; Bone Marrow Cells; Bucladesine; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Cells, Cultured; Colforsin; Culture Media, Conditioned; Cyclic AMP; Dendritic Cells; Dinoprostone; Gene Expression Regulation; Inflammation; Interleukin-12; Interleukin-12 Subunit p35; Interleukin-12 Subunit p40; Interleukin-17; Interleukin-23; Interleukin-23 Subunit p19; Interleukins; Lipopolysaccharides; Male; Mice; Misoprostol; Plasmacytoma; Prostaglandin Antagonists; Protein Subunits; Receptors, Cell Surface; Second Messenger Systems; Specific Pathogen-Free Organisms; Toll-Like Receptor 2; Toll-Like Receptor 4 | 2004 |
Transcriptional regulation of cyclooxygenase-2 gene in pancreatic beta-cells.
Topics: Animals; CCAAT-Enhancer-Binding Proteins; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Dinoprostone; Gene Expression Regulation, Enzymologic; Islets of Langerhans; Isoenzymes; Mice; Mutation; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Receptors, Aryl Hydrocarbon; Transcription, Genetic; Transcriptional Activation | 2004 |
Prostaglandin E2--mediated relaxation of the ductus arteriosus: effects of gestational age on g protein-coupled receptor expression, signaling, and vasomotor control.
Topics: 16,16-Dimethylprostaglandin E2; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylyl Cyclases; Alprostadil; Animals; Biphenyl Compounds; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Ductus Arteriosus; Enzyme Activation; Female; Gestational Age; Glyburide; Indomethacin; Isometric Contraction; NG-Nitroarginine Methyl Ester; Nitroprusside; Papio; Potassium Channels; Pregnancy; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sheep; Signal Transduction; Sodium Fluoride; Thionucleotides; Vasomotor System | 2004 |
Activation of HTLV-I gene transcription by protein tyrosine phosphatase inhibitors.
Topics: Cell Line; Colforsin; Cyclic AMP Response Element-Binding Protein; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation, Viral; Gene Products, tax; Human T-lymphotropic virus 1; Humans; Intracellular Signaling Peptides and Proteins; Organometallic Compounds; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Terminal Repeat Sequences; Transcription, Genetic; Vanadates; Virus Activation; ZAP-70 Protein-Tyrosine Kinase | 2004 |
Regulation of thrombomodulin expression in human vascular smooth muscle cells by COX-2-derived prostaglandins.
Topics: Alprostadil; Blood Coagulation; Bucladesine; Carotid Artery Diseases; Carotid Artery, Internal; Cells, Cultured; Colforsin; Coronary Vessels; Culture Media, Serum-Free; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Epoprostenol; Etoricoxib; Gene Expression Profiling; Gene Expression Regulation; Humans; Iloprost; Isoquinolines; Mammary Arteries; Membrane Proteins; Models, Biological; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyridines; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; RNA, Messenger; Saphenous Vein; Second Messenger Systems; Sulfonamides; Sulfones; Tetradecanoylphorbol Acetate; Thrombomodulin; Thrombophilia; Vasodilator Agents | 2005 |
Chronic hyperalgesic priming in the rat involves a novel interaction between cAMP and PKCepsilon second messenger pathways.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Analysis of Variance; Animals; Behavior, Animal; Carrageenan; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hyperalgesia; Male; Models, Biological; Pain Measurement; Pain Threshold; Protein Kinase C; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Thionucleotides | 2005 |
Bidirectional regulation of AQP2 trafficking and recycling: involvement of AQP2-S256 phosphorylation.
Topics: Animals; Antibody Specificity; Aquaporin 2; Aquaporins; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dogs; Dopamine; Endocytosis; Isoquinolines; Kidney; Male; Phosphorylation; Protein Kinase Inhibitors; Protein Transport; Rats; Rats, Sprague-Dawley; Renal Agents; Serine; Sulfonamides; Vasopressins | 2005 |
Effect of prostaglandin E2 on PMA-induced macrophage differentiation.
Topics: Cell Adhesion; Cell Differentiation; Colforsin; Dinoprostone; HL-60 Cells; Humans; Macrophages; Matrix Metalloproteinase 9; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2005 |
Primary afferent second messenger cascades interact with specific integrin subunits in producing inflammatory hyperalgesia.
Topics: Animals; Colforsin; Dinoprostone; Epinephrine; Ganglia, Spinal; Hyperalgesia; Inflammation; Integrins; Male; Rats; Rats, Sprague-Dawley; Signal Transduction | 2005 |
Vascular endothelial growth factor induction by prostaglandin E2 in human airway smooth muscle cells is mediated by E prostanoid EP2/EP4 receptors and SP-1 transcription factor binding sites.
Topics: Base Sequence; Binding Sites; Cell Survival; Cells, Cultured; Chromatin Immunoprecipitation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Gene Deletion; Humans; Isoproterenol; Luciferases; Molecular Sequence Data; Mutation; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Protein Binding; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; RNA; RNA, Messenger; Sp1 Transcription Factor; Time Factors; Trachea; Transcription, Genetic; Transfection; Vascular Endothelial Growth Factor A | 2005 |
Prostanoids secreted by alveolar macrophages enhance ionic currents in swine tracheal submucosal gland cells.
Topics: Acetylcholine; Animals; Cells, Cultured; Chloride Channels; Colforsin; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cystic Fibrosis Transmembrane Conductance Regulator; Dexamethasone; Diffusion Chambers, Culture; Dinoprostone; Exocrine Glands; Indomethacin; Ion Channels; Macrophages, Alveolar; Male; Potassium Channels; Prostaglandins; Swine; Trachea; Zymosan | 2005 |
Fibrotic lung fibroblasts show blunted inhibition by cAMP due to deficient cAMP response element-binding protein phosphorylation.
Topics: Blotting, Western; Cell Line; Cell Proliferation; Colforsin; Collagen; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; DNA; Electrophoretic Mobility Shift Assay; Fibroblasts; Humans; Phosphorylation; Pulmonary Fibrosis; Reverse Transcriptase Polymerase Chain Reaction; Smad Proteins; Transforming Growth Factor beta | 2005 |
Segmental heterogeneity of electrogenic secretions in human ascending colon and rectum.
Topics: 1-Methyl-3-isobutylxanthine; Carbachol; Chloride Channels; Colforsin; Colon; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprostone; Electrophoresis, Agar Gel; Electrophysiology; Humans; Intestinal Mucosa; Ion Transport; KCNQ1 Potassium Channel; Rectum; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
Effects of forskolin on Kupffer cell production of interleukin-10 and tumor necrosis factor alpha differ from those of endogenous adenylyl cyclase activators: possible role for adenylyl cyclase 9.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Down-Regulation; Enzyme Activation; Enzyme Activators; Gene Expression Regulation; Interleukin-10; Isoproterenol; Kupffer Cells; Protein Isoforms; Rats; Rats, Sprague-Dawley; Signal Transduction; Thionucleotides; Tumor Necrosis Factor-alpha | 2005 |
Characteristics of acid extrusion from Chinese hamster ovary cells expressing different prostaglandin EP receptors.
Topics: Animals; Calcium; CHO Cells; Colforsin; Cricetinae; Data Interpretation, Statistical; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Female; Humans; Hydrogen-Ion Concentration; Ovary; Pertussis Toxin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype | 2006 |
Beta-adrenergic receptor agonists induce the release of granulocyte chemotactic protein-2, oncostatin M, and vascular endothelial growth factor from macrophages.
Topics: Adrenergic beta-Agonists; Bucladesine; Chemokine CXCL6; Chemokines, CXC; Clenbuterol; Colforsin; Cyclic AMP; Cytokines; Dinoprostone; Humans; Lipopolysaccharides; Macrophage Activation; Macrophages; Oncostatin M; Trimethylsilyl Compounds; U937 Cells; Up-Regulation; Vascular Endothelial Growth Factor A | 2006 |
Involvement of the anion exchanger SLC26A6 in prostaglandin E2- but not forskolin-stimulated duodenal HCO3- secretion.
Topics: Animals; Antiporters; Bicarbonates; Carbachol; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprostone; Disease Models, Animal; Duodenum; Humans; Intestinal Mucosa; Mice; Mice, Inbred Strains; Mice, Knockout; Sulfate Transporters | 2006 |
Decreased prostaglandin E2 production by inflammatory cytokine and lower expression of EP2 receptor result in increased collagen synthesis in keloid fibroblasts.
Topics: Cells, Cultured; Colforsin; Collagen; Cyclic AMP; Cyclooxygenase 2; Dinoprostone; Fibroblasts; Humans; Immunohistochemistry; Interleukin-1; Keloid; Macrophage Migration-Inhibitory Factors; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phospholipases A; Phosphorylation; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger | 2006 |
Regulation of osteoclastogenesis by gap junction communication.
Topics: Animals; Base Sequence; Bone Resorption; Calcitriol; Carbenoxolone; Carrier Proteins; Cell Communication; Cell Differentiation; Cells, Cultured; Colforsin; Connexin 43; Dinoprostone; DNA, Complementary; Gap Junctions; Glycoproteins; Membrane Glycoproteins; Mice; Osteoclasts; Osteoprotegerin; Parathyroid Hormone; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; RNA, Messenger; Signal Transduction | 2006 |
Biphasic regulation by bile acids of dermal fibroblast proliferation through regulation of cAMP production and COX-2 expression level.
Topics: Alprostadil; Bile Acids and Salts; Cell Proliferation; Chenodeoxycholic Acid; Colforsin; Cyclic AMP; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Fibroblasts; Forearm; Humans; Liver Diseases; Membrane Proteins; RNA, Messenger; Skin | 2006 |
Identification, regulation and anti-proliferative role of the NPR-C receptor in gastric epithelial cells.
Topics: Adenylyl Cyclases; Animals; Atrial Natriuretic Factor; Cell Proliferation; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Epithelial Cells; Fluorescent Antibody Technique; Gastric Mucosa; Male; Protein Kinases; Rats; Rats, Wistar; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1 | 2006 |
Ileitis alters neuronal and enteroendocrine signalling in guinea pig distal colon.
Topics: Animals; Bethanechol; Cell Count; Colforsin; Colon; Dinoprostone; Enteroendocrine Cells; Epithelial Cells; Excitatory Postsynaptic Potentials; Guinea Pigs; Ileitis; Intestinal Mucosa; Ion Transport; Male; Motor Neurons; Muscarinic Agonists; Neurons; Neurons, Afferent; Serotonin; Signal Transduction; Trinitrobenzenesulfonic Acid; Veratridine | 2007 |
Cyclic AMP signaling contributes to neural plasticity and hyperexcitability in AH sensory neurons following intestinal Trichinella spiralis-induced inflammation.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dideoxyadenosine; Dinoprostone; Guinea Pigs; Histamine; Imidazoles; In Vitro Techniques; Intestinal Mucosa; Leukotriene B4; Lysine; Male; Membrane Potentials; Muscle, Smooth; Neuronal Plasticity; Neurons, Afferent; Nitric Oxide; Peroxidase; Signal Transduction; Substance P; Thiobarbituric Acid Reactive Substances; Trichinella spiralis; Trichinellosis; Tryptases | 2007 |
Persistent tetrodotoxin-resistant Na+ currents are activated by prostaglandin E2 via cyclic AMP-dependent pathway in C-type nodose neurons of adult rats.
Topics: Aging; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Electrophysiology; Ion Channel Gating; Male; Neurons; Nodose Ganglion; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium; Tetrodotoxin; Up-Regulation | 2007 |
Tissue-specific mechanisms for CCN2/CTGF persistence in fibrotic gingiva: interactions between cAMP and MAPK signaling pathways, and prostaglandin E2-EP3 receptor mediated activation of the c-JUN N-terminal kinase.
Topics: Adult; Alprostadil; Cells, Cultured; Colforsin; Connective Tissue Growth Factor; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Fibrosis; Gene Expression Regulation; Gingiva; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Lung; MAP Kinase Signaling System; Mesangial Cells; Organ Specificity; p38 Mitogen-Activated Protein Kinases; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Transforming Growth Factor beta1 | 2007 |
Prostaglandin E2 enhances acetylcholine-induced, Ca2+-dependent ionic currents in swine tracheal mucous gland cells.
Topics: Acetylcholine; Animals; Boron Compounds; Calcium; Calcium Channel Blockers; Carrier Proteins; Cells, Cultured; Charybdotoxin; Colforsin; Dinoprostone; Epithelial Cells; Imidazoles; Ion Channels; Large-Conductance Calcium-Activated Potassium Channels; Male; Membrane Potentials; Mucous Membrane; Patch-Clamp Techniques; Peptide Fragments; Peptides; Potassium Channel Blockers; Prostaglandin Antagonists; Swine; Trachea; Xanthones | 2007 |
Indomethacin decreases EP2 prostanoid receptor expression in colon cancer cells.
Topics: Cell Line, Tumor; Colforsin; Colonic Neoplasms; Cyclic AMP; Dinoprostone; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Indomethacin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger | 2007 |
Sensitization to heat through G-protein-coupled receptor pathways in the isolated sciatic mouse nerve.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Colforsin; Dinoprostone; Hot Temperature; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxytocics; Receptors, G-Protein-Coupled; Sciatic Nerve; Signal Transduction; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2007 |
Aromatase expression in a human osteoblastic cell line increases in response to prostaglandin E(2) in a dexamethasone-dependent fashion.
Topics: Aromatase; Cell Line; Colforsin; Dexamethasone; Dinoprostone; Drug Synergism; Gene Expression Regulation, Enzymologic; Humans; Osteoblasts; Promoter Regions, Genetic; Protein Kinase Inhibitors; Receptors, Prostaglandin E; Up-Regulation | 2007 |
Control of cyclic AMP concentration in bovine endometrial stromal cells by arachidonic acid.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Animals; Arachidonic Acid; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Depression, Chemical; Dinoprostone; Endometrium; Female; Indoles; Maleimides; Paracrine Communication; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Kinase C; Stromal Cells; Tetradecanoylphorbol Acetate | 2007 |
Stimulation of prostanoid IP and EP(2) receptors dilates retinal arterioles and increases retinal and choroidal blood flow in rats.
Topics: Animals; Colforsin; Dinoprostone; Epoprostenol; Male; Methyl Ethers; Rats; Rats, Wistar; Receptors, Epoprostenol; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Regional Blood Flow; Retina; Retinal Artery; Retinal Vein; Vasodilator Agents | 2007 |
Cyclooxygenase-2/prostaglandin E2 accelerates the healing of gastric ulcers via EP4 receptors.
Topics: Animals; Benzamides; Benzoates; Bucladesine; Colforsin; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Lactones; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Stomach Ulcer; Sulfones; Vascular Endothelial Growth Factor A; Wound Healing | 2007 |
Prostanoids induce egr1 gene expression in cementoblastic OCCM cells.
Topics: Animals; Blotting, Northern; Blotting, Western; Carcinogens; Cell Line; Colforsin; Dental Cementum; Dinoprost; Dinoprostone; Early Growth Response Protein 1; Enzyme Activators; Gene Expression Regulation; Ionomycin; Ionophores; Mice; Prostaglandins; Prostaglandins F, Synthetic; Protein Kinase C; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Zinc Fingers | 2007 |
Prostaglandin E2 sensitizes primary sensory neurons to histamine.
Topics: Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Ganglia, Spinal; Histamine; Histamine Agonists; Inositol 1,4,5-Trisphosphate; Isoquinolines; Models, Biological; Neurons, Afferent; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfonamides; Time Factors | 2007 |
Plasticity of dendritic cell function in response to prostaglandin E2 (PGE2) and interferon-gamma (IFN-gamma).
Topics: Cell Differentiation; Cell Movement; Colforsin; Cytokines; Dendritic Cells; Dinoprostone; Elasticity; Flow Cytometry; Humans; Imidazoles; Immunophenotyping; Interferon-gamma; Monocytes | 2008 |
Prolonged heterologous beta2-adrenoceptor desensitization promotes proasthmatic airway smooth muscle function via PKA/ERK1/2-mediated phosphodiesterase-4 induction.
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Asthma; Butadienes; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Dinoprostone; Enzyme Induction; Humans; Isoquinolines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle Contraction; Muscle Relaxation; Nitriles; Pertussis Toxin; Phosphodiesterase 4 Inhibitors; Rabbits; Receptors, G-Protein-Coupled; Rolipram; Signal Transduction; Sulfonamides; Trachea | 2008 |
Alpha2 adrenoreceptor agonist regulates protein kinase C-induced heat shock protein 27 phosphorylation in C6 glioma cells.
Topics: Adrenergic alpha-Agonists; Alprostadil; Analysis of Variance; Animals; Bucladesine; Cell Line, Tumor; Colforsin; Cyclic AMP; Dexmedetomidine; Dinoprostone; Drug Interactions; Gene Expression Regulation, Neoplastic; Glioma; Heat-Shock Proteins; Phorbol Esters; Phosphorylation; Protein Kinase C; Rats; Serine; Time Factors | 2008 |
Protein kinase A anchoring via AKAP150 is essential for TRPV1 modulation by forskolin and prostaglandin E2 in mouse sensory neurons.
Topics: A Kinase Anchor Proteins; Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Ganglia, Spinal; Humans; Hyperalgesia; Immunoprecipitation; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neurons, Afferent; Phosphorylation; Protein Kinase C; Transfection; TRPV Cation Channels | 2008 |
Downregulation of protease-activated receptor-1 in human lung fibroblasts is specifically mediated by the prostaglandin E receptor EP2 through cAMP elevation and protein kinase A.
Topics: Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Down-Regulation; Fibroblasts; Humans; Lung; Oligopeptides; Protein Biosynthesis; Receptor, PAR-1; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA Stability; RNA, Messenger; Signal Transduction; Transcription Factors | 2008 |
Prostaglandin E2 reduces extracellular ATP-induced migration in cultured rat microglia.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Alprostadil; Animals; Animals, Newborn; Cell Movement; Cell Survival; Cells, Cultured; Colforsin; Dinoprostone; Enzyme Inhibitors; Extracellular Fluid; Microglia; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype | 2008 |
Effect of beta2-adrenoceptor agonists and other cAMP-elevating agents on inflammatory gene expression in human ASM cells: a role for protein kinase A.
Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-6; Interleukin-8; Myocytes, Smooth Muscle; Respiratory System; Salmeterol Xinafoate | 2008 |
Prostaglandin receptor EP2 protects dopaminergic neurons against 6-OHDA-mediated low oxidative stress.
Topics: Adrenergic Agents; Alprostadil; Animals; Cells, Cultured; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Humans; Mesencephalon; Neurons; Oxidative Stress; Oxidopamine; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Substantia Nigra; Tyrosine 3-Monooxygenase | 2008 |
Inhibitory effect of somatostatin on prostaglandin E2 synthesis by primary neonatal rat glial cells.
Topics: Amides; Animals; Animals, Newborn; Brain; Cells, Cultured; Colforsin; Culture Media; Culture Media, Serum-Free; Dinoprostone; Dose-Response Relationship, Drug; Encephalitis; Hormone Antagonists; Indoles; Isoquinolines; Lipopolysaccharides; Neuroglia; Nitrobenzenes; Octreotide; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Somatostatin; Somatostatin; Sulfonamides | 2008 |
Adenosine analogs and electromagnetic fields inhibit prostaglandin E2 release in bovine synovial fibroblasts.
Topics: Adenosine; Animals; Binding, Competitive; Cattle; Cells, Cultured; Colforsin; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Electromagnetic Fields; Fibroblasts; Lipopolysaccharides; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; Synovial Fluid; Tumor Necrosis Factor-alpha | 2009 |
Role of the hyperpolarization-activated current Ih in somatosensory neurons.
Topics: Action Potentials; Animals; Animals, Newborn; Cell Size; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Dinoprostone; Electric Stimulation; Ganglia, Spinal; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Isoquinolines; Menthol; Mice; Mice, Inbred Strains; Mice, Knockout; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Wistar; Sensory Receptor Cells; Sulfonamides; TRPM Cation Channels | 2008 |
Altered hippocampal long-term synaptic plasticity in mice deficient in the PGE2 EP2 receptor.
Topics: Alprostadil; Animals; Animals, Newborn; Colforsin; Cyclooxygenase Inhibitors; Dinoprostone; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Maze Learning; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neurons; Nitrobenzenes; Patch-Clamp Techniques; Physical Phenomena; Reaction Time; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Sulfonamides; Synapses; Time Factors | 2009 |
[Regulation of receptor activator of nuclear factor kappaB ligand and osteoprotegerin expression by prostaglandin E2 in osteoblastic-like cells].
Topics: Animals; Bucladesine; Cell Line; Colforsin; Dinoprostone; Gene Expression Regulation; Osteoblasts; Osteoprotegerin; RANK Ligand; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
Funny currents are becoming serious players in nociceptor's sensitization.
Topics: Action Potentials; Animals; Cell Size; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Dinoprostone; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Mice; Mice, Knockout; Nociceptors; Potassium Channel Blockers; Potassium Channels; Pyrimidines; Rats; Sensory Receptor Cells | 2008 |
Regulation of Nur77 gene expression by prostanoids in cementoblastic cells.
Topics: Alprostadil; Animals; Calcium Signaling; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dental Cementum; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression Regulation; Mice; Misoprostol; Nuclear Receptor Subfamily 4, Group A, Member 1; Prostaglandins; Prostaglandins F, Synthetic; Protein Kinase C; Receptors, Prostaglandin; Receptors, Prostaglandin E; Signal Transduction; Time Factors | 2009 |
Impact of anti-inflammatory agents on the gene expression profile of stimulated human neutrophils: unraveling endogenous resolution pathways.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Colforsin; Dinoprostone; Gene Expression; Gene Expression Profiling; Humans; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligonucleotide Array Sequence Analysis; Oxytocics; Phenethylamines; Phosphodiesterase Inhibitors; Signal Transduction | 2009 |
Forskolin increases angiogenesis through the coordinated cross-talk of PKA-dependent VEGF expression and Epac-mediated PI3K/Akt/eNOS signaling.
Topics: Animals; Cell Proliferation; Chick Embryo; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Endothelial Cells; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Guanine Nucleotide Exchange Factors; Humans; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Up-Regulation; Vascular Endothelial Growth Factor A | 2009 |
Control of tight junctional sealing: roles of epidermal growth factor and prostaglandin E2.
Topics: Animals; Cell Line; Colforsin; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dogs; Electric Impedance; Epidermal Growth Factor; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Humans; Receptors, Prostaglandin E; Tight Junctions | 2009 |
Prostaglandin E2 inhibits the proliferation of human gingival fibroblasts via the EP2 receptor and Epac.
Topics: Cell Proliferation; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Fibroblasts; Gingiva; Guanine Nucleotide Exchange Factors; Humans; Phosphorylation; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction | 2009 |
Prostaglandin E2 inhibits advanced glycation end product-induced adhesion molecule expression, cytokine production, and lymphocyte proliferation in human peripheral blood mononuclear cells.
Topics: Adenylyl Cyclases; Bucladesine; Cell Adhesion Molecules; Cell Proliferation; Cell Separation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytokines; Dinoprostone; Enzyme Activation; Flow Cytometry; Glycation End Products, Advanced; Humans; In Vitro Techniques; Isoquinolines; Lymphocytes; Monocytes; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfonamides | 2009 |
Prostaglandin E2 promotes Na1.8 trafficking via its intracellular RRR motif through the protein kinase A pathway.
Topics: Amino Acid Motifs; Animals; Cell Culture Techniques; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Ganglia, Spinal; Humans; Hyperalgesia; Male; NAV1.8 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Protein Transport; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Channels | 2010 |
Prostaglandin E2-induced colonic secretion in patients with and without colorectal neoplasia.
Topics: Alprostadil; Biopsy; Bumetanide; Colforsin; Colon; Colorectal Neoplasms; Dinoprostone; Female; Humans; Ion Transport; Lubiprostone; Male; Middle Aged; Ouabain; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin E; Reference Values; Signal Transduction; Tamoxifen; Theophylline | 2010 |
Effects of sex and estrogen on chicken ductus arteriosus reactivity.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Acetylcholine; Animals; Calcium; Chick Embryo; Chickens; Colforsin; Dinoprostone; Ductus Arteriosus; Estradiol; Female; Male; Nitroprusside; Norepinephrine; Oxygen; Potassium Channel Blockers; Potassium Chloride; Pyrazoles; Pyridines; Receptors, Estrogen; Sex Characteristics; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2010 |
Molecular assays for characterization of alternatively spliced isoforms of the u opioid receptor (MOR).
Topics: Alternative Splicing; Animals; Calcium; Capsaicin; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Humans; Nitric Oxide; Protein Isoforms; Receptors, Opioid, mu; Sensory System Agents; Signal Transduction | 2010 |
Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- and phosphatidylinositol 3-kinase-dependent NF-kappaB activation.
Topics: Adenylyl Cyclases; Androstadienes; Binding Sites; Cells, Cultured; Chondrocytes; Chromones; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Activation; Enzyme Activators; Humans; Interleukin-6; Morpholines; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Promoter Regions, Genetic; Protein Kinase Inhibitors; RNA Interference; RNA, Messenger; Signal Transduction; Time Factors; Transcription Factor RelA; Transcriptional Activation; Up-Regulation; Wortmannin | 2010 |
C2-ceramide inhibits the prostaglandin E2-induced accumulation of cAMP in human gingival fibroblasts.
Topics: Arthritis, Rheumatoid; Cell Differentiation; Ceramides; Colforsin; Dinoprostone; Fibroblasts; Gingiva; Humans; Methyl Ethers; Prostaglandins E; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger; Signal Transduction; Sphingomyelins; Sphingosine | 2010 |
Targeted disruption of Mapk14 (p38MAPKalpha) in granulosa cells and cumulus cells causes cell-specific changes in gene expression profiles that rescue COC expansion and maintain fertility.
Topics: Amphiregulin; Animals; Cell Proliferation; Cells, Cultured; Colforsin; Cumulus Cells; Dinoprostone; EGF Family of Proteins; Female; Fertility; Follicle Stimulating Hormone; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation; Gene Targeting; Glycoproteins; Humans; Intercellular Signaling Peptides and Proteins; Mice; Mitogen-Activated Protein Kinase 14; Oocytes; Organ Specificity; Protein Kinase Inhibitors; Protein Transport; Signal Transduction | 2010 |
Tumor-secreted PGE2 inhibits CCL5 production in activated macrophages through cAMP/PKA signaling pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Infections; Cell Line; Chemokine CCL5; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Interferon-gamma; Interleukin-2; Isoquinolines; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitrobenzenes; Prostaglandin Antagonists; Protein Kinase Inhibitors; Shock, Septic; Signal Transduction; Sulfonamides; Tumor Escape; Xanthones | 2011 |
Diverse patterns of cyclooxygenase-independent metalloproteinase gene regulation in human monocytes.
Topics: Cell Adhesion; Colforsin; Dinoprostone; Fibronectins; Gene Expression Regulation; Humans; Inflammation; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Metalloproteases; Monocytes; NF-kappa B p52 Subunit; p38 Mitogen-Activated Protein Kinases; Phytotherapy; Plant Preparations; Plastics; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Signal Transduction; Tissue Inhibitor of Metalloproteinases; Up-Regulation | 2011 |
Tissue-specific regulation of aromatase promoter II by the orphan nuclear receptor LRH-1 in breast adipose stromal fibroblasts.
Topics: Adipose Tissue; Aromatase; Breast; Breast Neoplasms; Chromatin Immunoprecipitation; Colforsin; Dinoprostone; Female; Fibroblasts; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Organ Specificity; Postmenopause; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; RNA, Small Interfering; Stromal Cells; Tetradecanoylphorbol Acetate; Transfection | 2011 |
Up-regulation of tetrodotoxin-sensitive sodium currents by prostaglandin E₂ in type-4 rat dorsal root ganglion cells.
Topics: Animals; Biophysics; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Drug Interactions; Ganglia, Spinal; Male; Markov Chains; Models, Biological; Patch-Clamp Techniques; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sodium Channel Blockers; Sodium Channels; Statistics, Nonparametric; Tetrodotoxin; Thionucleotides; Up-Regulation | 2011 |
Cyclic AMP induces apoptosis in multiple myeloma cells and inhibits tumor development in a mouse myeloma model.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Survival; Colforsin; Cyclic AMP; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Intracellular Space; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Multiple Myeloma; Poly(ADP-ribose) Polymerases; Thionucleotides; Time Factors; Tumor Burden | 2011 |
Cyclic AMP increases COX-2 expression via mitogen-activated kinase in human myometrial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Dinoprostone; Female; Gene Expression Regulation; Humans; Mitogen-Activated Protein Kinases; Myometrium; Phosphorylation; RNA, Small Interfering; Rolipram; Sequence Analysis, DNA | 2012 |
YC-1 potentiates cAMP-induced CREB activation and nitric oxide production in alveolar macrophages.
Topics: Animals; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Activators; Guanylate Cyclase; Immunoblotting; Indazoles; Isoquinolines; Lung Diseases; Macrophages, Alveolar; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphoric Diester Hydrolases; Rats; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Sulfonamides | 2012 |
PGE(2) reverses G(s)-mediated inhibition of platelet aggregation by interaction with EP3 receptors, but adds to non-G(s)-mediated inhibition of platelet aggregation by interaction with EP4 receptors.
Topics: Acrylamides; Blood Platelets; Cell Adhesion Molecules; Colforsin; Cyclic AMP; Dinoprostone; Humans; Microfilament Proteins; Naphthalenes; Phenylbutyrates; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Antagonists; Quinazolines; Receptors, G-Protein-Coupled; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfones | 2012 |
EP4 receptor signalling in immature B cells involves cAMP and NF-κB dependent pathways.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Line; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; I-kappa B Proteins; Immune System Diseases; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Precursor Cells, B-Lymphoid; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction | 2012 |
Attenuation of inhibitory prostaglandin E2 signaling in human lung fibroblasts is mediated by phosphodiesterase 4.
Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Aminopyridines; Benzamides; Cells, Cultured; Chemotaxis; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Dinoprostone; Fibroblasts; Fibronectins; Gene Expression; Humans; Iloprost; Isoenzymes; Lung; Phosphodiesterase 4 Inhibitors; Pulmonary Disease, Chronic Obstructive; Receptors, Epoprostenol; Receptors, Prostaglandin; Receptors, Prostaglandin E, EP2 Subtype; Rolipram; Second Messenger Systems | 2012 |
Prostaglandin E(2) inhibits proteinase-activated receptor 2-signal transduction through regulation of receptor internalization.
Topics: Animals; Cell Line, Tumor; Colforsin; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Humans; Mice; Oligopeptides; Receptor, PAR-2; Signal Transduction | 2013 |
Scaffolding by A-kinase anchoring protein enhances functional coupling between adenylyl cyclase and TRPV1 channel.
Topics: A Kinase Anchor Proteins; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Capsaicin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Ganglia, Spinal; HEK293 Cells; Humans; Hyperalgesia; Mice; Multiprotein Complexes; Nerve Tissue Proteins; Protein Kinase C; Sensory System Agents; TRPV Cation Channels | 2013 |
Selective inhibition of cell death in malignant vs normal B-cell precursors: implications for cAMP in development and treatment of BCP-ALL.
Topics: Adolescent; Adult; Apoptosis; Blast Crisis; Case-Control Studies; Cells, Cultured; Child; Child, Preschool; Colforsin; Cyclic AMP; Dinoprostone; DNA Damage; Female; Humans; Infant; Male; Oxytocics; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cells, B-Lymphoid; Tumor Suppressor Protein p53; Young Adult | 2013 |
Prostaglandin E2 promotes liver cancer cell growth by the upregulation of FUSE-binding protein 1 expression.
Topics: Abortifacient Agents, Nonsteroidal; Adenine; Adenylyl Cyclase Inhibitors; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colforsin; Cyclic AMP; Dinoprostone; DNA Helicases; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Humans; Isoquinolines; Liver Neoplasms; Nuclear Proteins; Pertussis Toxin; Phosphorylation; Protein Kinase Inhibitors; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; RNA Interference; RNA-Binding Proteins; RNA, Small Interfering; Smad2 Protein; Sulfonamides; Ubiquitination | 2013 |
Pain modulators regulate the dynamics of PKA-RII phosphorylation in subgroups of sensory neurons.
Topics: Animals; Biomarkers; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit; Cyclic AMP-Dependent Protein Kinase Type I; Cyclosporine; Dinoprostone; Gene Expression Regulation; Male; NAV1.8 Voltage-Gated Sodium Channel; Nociception; Phosphorylation; Primary Cell Culture; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Signal Transduction; TRPV Cation Channels | 2014 |
Prostaglandin E2 promotes MYCN non-amplified neuroblastoma cell survival via β-catenin stabilization.
Topics: Adolescent; Apoptosis; beta Catenin; Cell Cycle; Cell Line, Tumor; Cell Survival; Child; Child, Preschool; Colforsin; Cyclic AMP; Cyclooxygenase 2 Inhibitors; Dinoprostone; Female; Gene Amplification; Humans; Infant; Male; Mutant Proteins; N-Myc Proto-Oncogene Protein; Neuroblastoma; Nuclear Proteins; Oncogene Proteins; Protein Stability; Transcription, Genetic; Young Adult | 2015 |
Regulation of ovulatory genes in bovine granulosa cells: lessons from siRNA silencing of PTGS2.
Topics: Animals; Biomarkers; Blotting, Western; Cattle; Cells, Cultured; Colforsin; Cyclooxygenase 2; Dinoprostone; Female; Gene Expression Regulation; Granulosa Cells; Luteinizing Hormone; Ovulation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Vasodilator Agents | 2015 |
Endogenous prostaglandin E2 potentiates anti-inflammatory phenotype of macrophage through the CREB-C/EBP-β cascade.
Topics: Animals; Arginase; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Female; Gene Expression Regulation; Indomethacin; Interleukin-10; Isoquinolines; Macrophage Colony-Stimulating Factor; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Phenotype; Primary Cell Culture; Prostaglandin-Endoperoxide Synthases; Receptors, Cell Surface; Receptors, Immunologic; Signal Transduction; Sulfonamides | 2015 |
Regulatory Action of Calcium Ion on Cyclic AMP-Enhanced Expression of Implantation-Related Factors in Human Endometrial Cells.
Topics: Alamethicin; Biomarkers; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Chelating Agents; Colforsin; Cyclic AMP; Cyclooxygenase 2; Dantrolene; Decidua; Dinoprostone; Embryo Implantation; Endometrium; Female; Humans; Ionophores; Ions; Models, Biological; Ryanodine Receptor Calcium Release Channel; Stromal Cells | 2015 |
Comprehensive Profiling of GPCR Expression in Ghrelin-Producing Cells.
Topics: Adrenergic beta-Agonists; Animals; Cell Line, Tumor; Colforsin; Dinoprostone; Gastric Mucosa; Gene Expression Profiling; Ghrelin; Hormones; Immunohistochemistry; Isoproterenol; Lactic Acid; Mice; Mice, Transgenic; Muscarine; Muscarinic Agonists; Oxytocics; Oxytocin; Palmitates; Receptor, Muscarinic M4; Receptors, Adrenergic, beta-1; Receptors, G-Protein-Coupled; Receptors, Oxytocin; Receptors, Prostaglandin E, EP4 Subtype; Receptors, Somatostatin; RNA, Messenger; Sequence Analysis, RNA; Somatostatin; Tryptophan | 2016 |
Prostaglandin E2 inhibits collagen synthesis in dermal fibroblasts and prevents hypertrophic scar formation in vivo.
Topics: Animals; Azetidines; Cicatrix; Colforsin; Collagen; Cyclic AMP; Cyclooxygenase 2; Dinoprostone; Drug Evaluation, Preclinical; Female; Fibroblasts; Humans; Isoindoles; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Rabbits; Signal Transduction; Smad Proteins; Sulfonamides; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1 | 2016 |
Prostaglandin E2-Dependent Phosphorylation of RAS Inhibition 1 (RIN1) at Ser 291 and 292 Inhibits Transforming Growth Factor-β-Induced RAS Activation Pathway in Human Synovial Fibroblasts: Role in Cell Migration.
Topics: Cell Movement; Colforsin; Dinoprostone; Fibroblasts; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Phosphorylation; ras Proteins; Signal Transduction; Transforming Growth Factor beta | 2017 |
Long-term exposure to PGE2 causes homologous desensitization of receptor-mediated activation of protein kinase A.
Topics: Adjuvants, Immunologic; Animals; Capsaicin; Cells, Cultured; Chromones; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Eicosanoids; Enzyme Inhibitors; Ganglia, Spinal; Isoquinolines; Male; Morpholines; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E, EP4 Subtype; Sensory Receptor Cells; Sensory System Agents; Signal Transduction; Sulfonamides; Time Factors | 2016 |
Prostaglandin E2 receptor EP4 is involved in the cell growth and invasion of prostate cancer via the cAMP‑PKA/PI3K‑Akt signaling pathway.
Topics: Adenylyl Cyclases; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colforsin; Core Binding Factor Alpha 1 Subunit; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Phosphatidylinositol 3-Kinase; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; RANK Ligand; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Up-Regulation | 2018 |
Budesonide enhances agonist-induced bronchodilation in human small airways by increasing cAMP production in airway smooth muscle.
Topics: Bronchi; Bronchodilator Agents; Budesonide; Carbachol; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Fluticasone; Formoterol Fumarate; Humans; Muscle, Smooth; Myosin Light Chains; Phosphorylation; Prednisone; Receptors, Glucocorticoid | 2020 |
cAMP signaling primes lung endothelial cells to activate caspase-1 during
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Alprostadil; Animals; Caspase 1; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Endothelial Cells; Gene Expression Regulation; Host-Pathogen Interactions; Inflammasomes; Interleukin-1beta; Lung; Primary Cell Culture; Pseudomonas aeruginosa; Rats; Rolipram; Signal Transduction; Single-Cell Analysis | 2020 |
Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Child; Chromogranins; Colforsin; Cyclic AMP; Dexamethasone; Dinoprostone; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Leukemic; GTP-Binding Protein alpha Subunits, Gs; Humans; Male; Mice; Models, Animal; Molecular Targeted Therapy; Neoplasm Proteins; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Radiation Chimera; Receptors, Glucocorticoid; Receptors, Prostaglandin E, EP4 Subtype; RNA Interference; RNA, Small Interfering; Second Messenger Systems; Xenograft Model Antitumor Assays | 2021 |
Modulation of carbachol-induced Ca
Topics: Animals; Calcium; Carbachol; Colforsin; Dinoprostone; Mice; Muscle Contraction; Muscle, Smooth; Myocytes, Smooth Muscle | 2022 |