colforsin has been researched along with cyclic gmp in 395 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (15.70) | 18.7374 |
| 1990's | 202 (51.14) | 18.2507 |
| 2000's | 105 (26.58) | 29.6817 |
| 2010's | 25 (6.33) | 24.3611 |
| 2020's | 1 (0.25) | 2.80 |
| Authors | Studies |
|---|---|
| Christian, C; Harrowe, G; Mitsuhashi, M; Ohashi, Y; Payan, DG; Shichijo, S; Sudduth-Klinger, J | 1 |
| Assender, JW; Hallett, MB; Newby, AC; Southgate, KM | 1 |
| Noma, A; Ono, K; Tareen, FM; Yoshida, A | 1 |
| Altiok, N; Fredholm, BB | 1 |
| Amano, T; Okabe, N; Yamakuni, T; Yamamoto, T | 1 |
| Colbran, JL; Corbin, JD; Francis, SH; Jiang, H | 1 |
| Boulanger, CM; Vanhoutte, PM | 1 |
| Bolsover, SR; Gilbert, SH; Spector, I | 1 |
| Agli, B; Giudicelli, Y; Lacasa, D | 1 |
| Edwards, DH; Griffith, TM; Renowden, S | 1 |
| Heuzé-Joubert, I; Laubie, M; Mennecier, P; Simonet, S; Verbeuren, TJ | 1 |
| Reiser, G | 2 |
| Bochkov, V; Buhler, F; Resink, T; Tkachuk, V | 1 |
| Emeis, JJ; Tranquille, N | 2 |
| Buchan, KW; Martin, W | 2 |
| Gray, DW; Marshall, I | 1 |
| Cusson, M; Guan, XC; Tobe, SS; Yagi, KJ | 1 |
| Conklin, JL; Du, C | 1 |
| Iga, T; Maeno, N | 1 |
| Schröder, H; Schrör, K; Strobach, H | 1 |
| Zatz, M | 1 |
| Ache, BW; Michel, WC | 1 |
| Barber, R; Butcher, RW; Goka, TJ | 1 |
| Dym, M; Kleinman, HK; Papadopoulos, V; Weeks, BS | 1 |
| Bauer, C; Eckardt, KU; Kurtz, A; Scholz, H; Schurek, HJ | 1 |
| Diener, M; Mestres, P; Nobles, M; Rummel, W | 1 |
| Evinger, MJ; Meeley, MP; Regunathan, S; Reis, DJ | 1 |
| Tait, JF; Thiagarajan, P | 1 |
| de Vente, J; Dinger, B; Fidone, SJ; Stensaas, LJ; Wang, ZZ | 1 |
| Gordon, PB; Holen, I; Seglen, PO | 1 |
| Roberts, JM; Russell, JA | 1 |
| Ono, K; Trautwein, W | 1 |
| Zurn, AD | 1 |
| Gibson, A; Hobbs, AJ; Mirzazadeh, S; Tucker, JF | 1 |
| Izumi, F; Okazaki, M; Terao, T; Uezono, Y; Wada, A; Yanagihara, N | 1 |
| Lugnier, C; Muller, B; Stoclet, JC | 1 |
| Fukuda, A; Minami, T; Nabekura, J; Oomura, Y | 1 |
| Beavo, J; Jacobson, KL; McPhee, C; Singh, JC; Watson, EL | 1 |
| Schwarzschild, MA; Zigmond, RE | 1 |
| Frings, S; Lindemann, B | 1 |
| De Mey, JG; Dijkstra, EH; Vrijdag, MJ | 1 |
| Wainwright, LK; Wainwright, SD | 1 |
| Hamet, P; Tremblay, J | 1 |
| Lachowicz, L; Turski, WA | 1 |
| Nunes, JP; Soares-da-Silva, P; Villanueva, MM | 1 |
| Anderson, RJ; Breckon, R; Colston, D | 1 |
| Dewey, D; Douglas, PB; Putnam, RW | 1 |
| Sperelakis, N; Tripathi, O | 1 |
| Leighton, J; Märki, F; Pfeilschifter, J; Pignat, W; Vosbeck, K | 1 |
| Chik, CL; Ho, AK | 1 |
| Currie, MG; Karnaky, KJ; Kennedy, MP; Oehlenschlager, WF; Valentich, JD | 1 |
| Audsley, N; Phillips, JE | 1 |
| Metsis, M; Neuman, T; Paves, H; Saarma, M | 1 |
| Barsony, J; Marx, SJ | 1 |
| Diocee, BK; Martin, W; Moodie, SA; Souness, JE | 1 |
| Cornwell, TL; Lincoln, TM; Taylor, AE | 1 |
| Diamond, J; Giembycz, MA | 1 |
| Howard, P; Massa, JS; Maurer, RA; Richardson, JM | 1 |
| Kaiser, PK; Lipton, SA | 1 |
| Blackshear, PJ; Lobaugh, LA | 1 |
| Stuart-Smith, K; Vanhoutte, PM | 1 |
| Mattila, P; Renkonen, R; Turunen, JP | 1 |
| Leidenberger, FA; Mukhopadhyay, AK; Temmen, N; Willey, KP | 1 |
| Alberts, P; Ogren, VR; Sellström, AI | 1 |
| Jacobson, KL; Singh, JC; Watson, EL | 1 |
| Assayag, E; Heisler, S; Labrie, F; Mehri, Y; Simard, J | 1 |
| Kwon, HB; Schuetz, AW | 1 |
| Ganten, D; Lang, RE; Ruskoaho, H; Toth, M; Unger, T | 1 |
| Cline, WH; Nickols, GA | 1 |
| Singh, JC; Watson, EL | 1 |
| Groome, JR; Watson, WH | 2 |
| Orekhov, AN; Smirnov, VN; Tertov, VV | 1 |
| Kirk, MD; Scheller, RH; Taussig, R | 1 |
| Hurwitz, S; Pines, M | 1 |
| Alberts, P; Ogren, VR | 1 |
| Iida, H; Page, E | 1 |
| Aghajanian, GK; Wang, YY | 1 |
| Berry, L; Brigham, KL; Graber, S; Hussein, A; Meyrick, B | 1 |
| Benishin, CG; Pang, PK; Zeng, YY | 1 |
| Kotecha, N; Neild, TO | 1 |
| Ishikawa, S; Sperelakis, N | 1 |
| Moummi, C; Rattan, S | 1 |
| Bowman, BF; Stull, JT; Taylor, DA | 1 |
| Owen, DA; Wood, LM | 1 |
| Chik, CL; Ho, AK; Klein, DC | 1 |
| Hamet, P; Pang, SC; Tremblay, J | 1 |
| Nishimura, J; van Breemen, C | 1 |
| Miledi, R; Woodward, RM | 1 |
| Cheng, GF; Dinger, BG; Fidone, SJ; Wang, WJ | 1 |
| Giesa, FR; Grimes, D; Heaslip, RJ; Rimele, TJ | 1 |
| Barrett, PQ; Isales, CM | 1 |
| Ousterhout, JM; Sperelakis, N | 1 |
| Linz, W; Schölkens, BA; Wiemer, G | 1 |
| Furukawa, K; Shigekawa, M; Tawada, Y | 1 |
| Mullen, DA; Zatz, M | 1 |
| Hagiwara, M; Hidaka, H; Ishikawa, T; Itoh, H; Onoda, K; Tanaka, T | 1 |
| Kusel, M; Lucas, ML; McEwan, GT; McKie, AT | 1 |
| Ecker, T; Felbel, J; Hofmann, F; Landgraf, W; Trockur, B | 1 |
| Cornwell, TL; Lincoln, TM | 1 |
| Hubbard, CJ; Price, J | 1 |
| Ernst, SA; Lowy, RJ | 1 |
| Mittag, TW; Ortega, M; Severin, C; Tormay, A | 1 |
| Burgess, MN; Daniel, H; Fett, C; Lucas, ML; McEwan, GT | 1 |
| Bowman, WC; Lam, FY; Rodger, IW; Shahid, M | 1 |
| Baker, CA; Harris, DW; Johnson, GA; Saneii, HH | 1 |
| Ishikawa, S; Kangawa, K; Kuzuya, T; Matsuo, H; Okada, K; Saito, T | 1 |
| Murad, F; Rapoport, RM; Schwartz, K; Waldman, SA; Winquist, RJ | 1 |
| Connelly-Fittingoff, M; Fernandez, EI; Krall, JF | 1 |
| Koenig, RJ | 1 |
| Anderson, RJ; Dillingham, MA | 1 |
| McMahon, EG; Paul, RJ | 1 |
| Satake, T; Suzuki, K; Takagi, K; Tsukawaki, M | 1 |
| Diamond, J; MacLeod, KM | 1 |
| Kimura, A; Nakagawa, H; Ohuchi, T; Oka, M | 1 |
| Chiba, S; Horiuchi, A; Iwatsuki, K; Yamagishi, F | 1 |
| Fisher-Simpson, V; Lincoln, TM | 1 |
| Macleod, KM | 1 |
| Evans, PD | 1 |
| Dartt, DA; Donowitz, M; Joshi, VJ; Mathieu, RS; Sharp, GW | 1 |
| Brown, JE; Kaupp, UB; Malbon, CC | 1 |
| Aloj, SM; Brandi, ML; Kohn, LD; Lopponi, A; Rotella, CM; Toccafondi, R | 1 |
| Saito, Y; Wright, EM | 1 |
| Rodger, IW; Shahid, M | 1 |
| Alousi, AA; Farah, AE; Schwarz, RP | 1 |
| Bertaccini, G; Coruzzi, G; Poli, E; Pozzoli, C | 1 |
| Satoh, K; Taira, N; Yamagishi, T; Yanagisawa, T | 1 |
| Alexander, SP; Hernández, F; Kendall, DA | 1 |
| Frelin, C; Lund, L; Vigne, P | 1 |
| Alessio, P; Bussolino, F; Calvino, R; Fruttero, R; Gasco, A; Ghigo, D; Heller, R; Pescarmona, G; Till, U; Todde, R | 1 |
| de Bessé, N; Lachaise, F; Saïdi, B; Sedlmeier, D; Webster, SG | 1 |
| Imai, A; Nashida, T; Shimomura, H | 1 |
| Amirchetty-Rao, S; Kendall, DA; Wright, IK | 1 |
| Halldorsson, H; Kjeld, M; Magnusson, A; Thorgeirsson, G | 1 |
| Cramb, G; Gilkes, AF; Guild, SB | 1 |
| Ko, FN; Kuo, SC; Lee, FY; Teng, CM; Wu, CC | 1 |
| Bergh, CM; Brophy, CM; Dransfield, DT; Goldenring, JR; Lincoln, T; Rasmussen, H | 1 |
| Ikeda, K; Sunose, H; Suzuki, M; Takasaka, T | 1 |
| Akesson, B; Lundquist, I; Panagiotidis, G; Rydell, EL | 1 |
| Armstead, WM; Devine, JO; Rebich, S | 1 |
| Hong, CY; Huang, YT; Lin, HC; Lo, JW; Tsai, YT; Yang, MC | 1 |
| Lefebvre, RA; Smits, GJ | 1 |
| Noma, A; Ono, K | 1 |
| Usachev, Y; Verkhratsky, A | 1 |
| Catalán, RE; Gargiulo, L; Liras, A; Martínez, AM | 1 |
| Hui, J; MacLeod, KM; Tabatabaei, A | 1 |
| Hong, LS; LaPolt, PS | 1 |
| Corvol, P; Della Bruna, R; Kurtz, A; Pinet, F | 1 |
| Arthur, AS; Kassell, NF; Lee, KS; Sutter, B; Suzuki, S | 1 |
| Houchi, H; Oka, M; Okuno, M; Shono, M; Tokumura, A | 1 |
| Cunningham, JM; Delaney, CA; Green, IC; Karmiris, V; Southern, C | 1 |
| Barnette, MS; Barone, FC; Manning, CD; Price, WJ | 1 |
| Matsuda, Y; Mukhopadhyay, AK; Schumacher, H | 1 |
| Bloch, DB; Bloch, KD; Janssens, SP; Shimouchi, A; Zapol, WM | 1 |
| Barger, SW; Fiscus, RR; Hofmann, F; Mattson, MP; Ruth, P | 1 |
| Castresana, MR; Newman, WH; Zhang, LM | 1 |
| Omiecinski, CJ; Sidhu, JS | 1 |
| Maggi, CA; Morbidelli, L; Parenti, A; Santicioli, P; Ziche, M | 1 |
| Castresana, MR; Newman, WH; Shillcutt, SD; Tao, H; Zhang, LM | 1 |
| Klein, DC; White, BH | 2 |
| Regunathan, S; Reis, DJ | 1 |
| Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, E; Trovati, M | 1 |
| Daniel, EE; Eng, R; Hipworth, S; Lu, S; McGrogan, I; Preocanin, D; Sormaz, L | 1 |
| Belhassen, L; Fischmeister, R; Méry, PF; Pavoine, C; Pecker, F | 1 |
| Fukami, T; Ihara, M; Ishikawa, K; Ozaki, S; Saeki, T; Yano, M | 1 |
| Itoh, H; Kishimoto, I; Komatsu, Y; Nakagawa, O; Nakao, K; Ogawa, Y; Suga, S; Yoshimasa, T | 1 |
| Drescher, P; Madsen, PO; Sparwasser, C; Will, JA | 1 |
| Bielefeld, DR; Lorenz, JN; Sperelakis, N | 1 |
| Cao, L; Gardner, DG; Zlock, DW | 1 |
| Dickinson, K; Foster, GA; Frodsham, G; Jones, RB | 1 |
| Copello, J; Heming, TA; Reuss, L | 1 |
| Hume, JR; Ishikawa, T; Keef, KD | 1 |
| Babinski, K; De Léan, A; Féthière, J; Graihle, R; Larose, L; Ong, H | 1 |
| Li, KX; Sperelakis, N | 1 |
| Franceschini, N; Hanyu, Y | 1 |
| Della Bruna, R; Kurtz, A; Schricker, K | 1 |
| Gewitz, MH; Hintze, TH; Mathew, R; Wang, J; Wolin, MS | 1 |
| Ko, FN; Lin, CH; Lu, ST; Teng, CM; Wu, YC | 1 |
| Berry, MS; Everill, B | 1 |
| Gurewich, V; Li, C; Liu, JN | 1 |
| Kashiwayanagi, M; Kurihara, K; Taniguchi, M | 1 |
| Carré, DA; Civan, MM | 1 |
| D'Souza, T; Dryer, SE | 1 |
| Baird, AW; Taylor, CT | 1 |
| Davis, M; de Lima, TC | 1 |
| Paulding, WR; Sumners, C | 1 |
| Garcia, R; Lacasse, A; Thibault, G | 1 |
| Forssmann, WG; Jonas, U; Kuczyk, M; Schulz-Knappe, P; Stief, CG; Truss, MC; Uckert, S | 1 |
| Komalavilas, P; Lincoln, TM | 1 |
| Baxter, JD; Costa, CH; Graf, H; Leitman, DC; Ribeiro, RC | 1 |
| Ingram, SL; Williams, JT | 1 |
| Camello, PJ; Petersen, OH; Toescu, EC | 1 |
| Delpy, E; le Monnier de Gouville, AC | 1 |
| Sirotkin, AV | 1 |
| Coste, H; Delpy, E; Gouville, AC | 1 |
| Raymond, GL; Wendt, IR | 1 |
| Boerth, N; Cornwell, TL; Greenwood, JA; Lincoln, TM; Murphy-Ullrich, JE; Pallero, MA | 1 |
| Matsumoto, S | 1 |
| Angelini, GD; Birkett, SD; Bryan, AJ; Jeremy, JY | 1 |
| Cobbett, P; Ramsell, KD | 1 |
| Sjöholm, A | 1 |
| Bucher, B; Côrtes, SF; Lemos, VS; Takeda, K | 1 |
| Drescher, P; Knes, JM; Madsen, PO; Rauch, D; Sparwasser, C | 1 |
| Laychock, SG; Lee, B | 1 |
| Kubo, T; Taguchi, K; Ueda, M | 1 |
| Cheng, K; Christodoulides, N; Durante, W; Peyton, KJ; Schafer, AI; Sunahara, RK | 1 |
| Gillard, ER; Grewal, RS; Khan, AM; Mouradi, B; Stanley, BG | 1 |
| Warashina, A | 1 |
| Amaral, J; Behar, J; Biancani, P; Chen, Q; Oh, S | 1 |
| Liu, H; Maurice, DH; Palmer, D; Rose, RJ | 1 |
| Aragonés, MD; Catalán, RE; Lombardía, M; Martínez, AM | 1 |
| Cornwell, TL; Cundiff, DL; Gately, S; Lincoln, TM; Soff, GA | 1 |
| Lee, HZ | 1 |
| Fullerton, DA; McIntyre, RC; Meldrum, DR; Sheridan, BC | 1 |
| Cotton, CU; Drumm, ML; Kelley, TJ | 1 |
| Franklin, A; Hariawala, MD; Li, J; Sellke, FW; Stamler, A; Tofukuji, M | 1 |
| Blumenstein, I; Colledge, WH; Evans, M; Gregor, M; Kretz, A; Ratcliff, R; Rossmann, H; Seidler, U; Viellard-Baron, D | 1 |
| Earm, YE; Han, J; Ho, WK; Kim, E; Lee, SH; Yoo, S | 1 |
| Kildalsen, H; Sager, G; Schultz, C; Vaskinn, S | 1 |
| Bocanera, LV; Juvenal, GJ; Krawiec, L; Pignataro, O; Pisarev, MA; Pregliasco, LB; Silberschmidt, D | 1 |
| Isayama, Y; Kohsaka, Y; Nasa, Y; Sanbe, A; Takeo, S; Toyoshima, H; Yamaguchi, F | 1 |
| Kidao, S; Merricks, EP; Pryzwansky, KB | 1 |
| Katusic, ZS; Onoue, H | 1 |
| Hume, JR; Keef, KD; Ruiz-Velasco, V; Zhong, J | 1 |
| Bolz, SS; Pohl, U | 1 |
| Haystead, TA; Nakamoto, RK; Somlyo, AP; Somlyo, AV; Wu, X | 1 |
| Endo, K; Nakamura, M; Nakata, K | 1 |
| Maurice, DH | 1 |
| Andell-Jonsson, S; Bartfai, T | 1 |
| Howlett, A; Klein, C; Najafi, L; Shipley, S; Tao, YP | 1 |
| Fujimoto, N; Hanawa, T; Kimura, T | 1 |
| Chang, W; Chen, TH; Pratt, S; Shoback, D | 1 |
| Atala, A; Goldstein, I; Moreland, RB; Park, K; Traish, A | 1 |
| Goldstein, JL; Layden, TJ; Moyer, MP; Nataraja, SG; Rao, MC; Sahi, J | 1 |
| von der Weid, PY | 1 |
| Hofmann, F; Kurtz, A; Pfeifer, A; Ruth, P; Wagner, C | 1 |
| Polte, T; Schröder, H | 1 |
| Gong, GX; Scholz, PM; Tse, J; Weiss, HR; Yan, L | 1 |
| Angelini, GD; Dashwood, MR; Izzat, MB; Jeremy, JY; Mehta, D; Shukla, N | 1 |
| Kamagata, S; Nakata, E; Ohta, M; Oshima, N | 1 |
| Liu, H; Maurice, DH | 1 |
| Flavahan, NA; Horibe, M; Murray, PA; Smedira, NG; Yoshida, K | 1 |
| Drummer, C; Gerzer, R; Herten, M; Lenz, W | 1 |
| Busse, R; Kronemann, N; Nockher, WA; Schini-Kerth, VB | 1 |
| Aardal, S; Helle, KB; Lillestłl, IK | 1 |
| Gupte, SA; Mohazzab-H, KM; Rupawalla, T; Wolin, MS | 1 |
| Hucks, D; Priest, RM; Ward, JP | 1 |
| Gong, GX; Scholz, PM; Straznicka, M; Tse, J; Weiss, HR | 1 |
| Dam, TV; Dulin, NO; Fortuno, MA; Hamet, P; Orlov, SN; Thorin-Trescases, N; Tremblay, J | 1 |
| Carlson, EJ; Drewett, JG; Kreklau, EL | 1 |
| Bai, Y; Fiscus, RR; Li, Y; Wang, W; Wang, X | 1 |
| Benjamin, PR; Willoughby, D; Yeoman, MS | 1 |
| Gong, GX; Scholz, PM; Straznicka, M; Tse, J; Weiss, HR; Yan, L | 1 |
| Berman, J; Goldstein, I; Huang, YH; Kim, NN; Moreland, RB; Traish, A | 1 |
| Dallos, P; He, DZ; Ribári, O; Sziklai, I; Szönyi, M | 1 |
| Tabrizchi, R | 1 |
| Hobbs, AJ; Hussain, MB; MacAllister, RJ | 1 |
| Gupte, SA; Iesaki, T; Wolin, MS | 1 |
| Gupte, SA; Phillibert, D; Rupawalla, T; Wolin, MS | 1 |
| Grealy, M; Sreenan, JM | 1 |
| Becker, AJ; Forssmann, WG; Harringer, W; Jonas, U; Stief, CG; Truss, MC; Uckert, S | 1 |
| Tsui, JK; Wong, BP; Wong, NL | 1 |
| Garfield, RE; Jain, V; Okawa, T; Saade, GR; Syal, AS; Vedernikov, YP | 1 |
| Aikawa, N; Karasawa, A; Ohmori, K | 1 |
| Champion, C; Greutert, H; Lüscher, TF; Meier, P; Nabel, EG; Tanner, FC | 1 |
| Haynes, JM | 1 |
| de Cingolani, GC; Mattiazzi, A; Mundiña-Weilenmann, C; Rinaldi, G; Said, M; Vittone, L | 1 |
| Bischoff, E; Jonas, U; Kühn, R; Lietz, B; Schramm, M; Stief, CG; Truss, MC; Uckert, S | 1 |
| Ikeda, M; Kawase, T; Matsumoto, S; Nishikawa, T; Takahashi, T; Yoshida, S | 1 |
| Bader, B; Burkhardt, M; Butt, E; Gambaryan, S; Glazova, M; Heermeier, K; Lincoln, TM; Palmetshofer, A; Vollkommer, T; Walter, U | 1 |
| Glasgow, NJ; Jun, JY; Kim, TW; Koh, SD; Sanders, KM; Ward, SM | 1 |
| Ahmad, M; Andersson, KE; Aszòdi, A; Fässler, R; Pandita, RK; Persson, K; Pfeifer, A | 1 |
| Berggren, PO; Cooney, RV; Sjöholm, A | 1 |
| Christophersen, P; Jensen, BS; Olesen, SP; Schrøder, RL; Strøbaek, D | 1 |
| Bilbe, G; Bowler, WB; Buckley, KA; Gallagher, JA; Gaw, A; Hipskind, RA; McKay, G; Wagstaff, SC | 1 |
| Chang, LS; Huang, WJ; Kan, SF; Wang, PS; Yeh, JY | 1 |
| Steinbusch, HW | 1 |
| Eguchi, D; Katusic, ZS | 1 |
| Eckhart, A; Gaballa, MA; Goldman, S; Koch, WJ | 1 |
| Hong, L; Ishimaru, RS; LaPolt, PS; Leung, K | 1 |
| Gandhi, A; Patel, KN; Scholz, PM; Weiss, HR; Yan, L | 1 |
| Choi, JC; Hahn, SJ; Jo, YH; Kim, MS; Kim, YC; Min, DS; Rhie, DJ; Shim, HS; Sim, SS; Yoon, SH | 1 |
| Bönisch, H; Bryan-Lluka, LJ; Paczkowski, FA | 1 |
| Alm, P; Henningsson, R; Lundquist, I | 1 |
| Gao, Y; Raj, JU | 1 |
| Haystead, TA; Liu, X; MacDonald, JA; Nakamoto, RK; Somlyo, AP; Somlyo, AV; Walker, LA | 1 |
| Van Helden, DF; von der Weid, PY; Zhao, J | 1 |
| Charles, A; Costantin, J; Weiner, R | 1 |
| Duszyk, M | 1 |
| Hare, JM; Isoda, T; Juang, GJ; Kass, DA; Mayer, SP; Ohler, A; Paolocci, N; Senzaki, H; Smith, CJ; Tomaselli, GF | 1 |
| Ikegaya, Y; Matsuki, N; Mizuhashi, S; Nishiyama, N | 1 |
| Clarkson, M; Murphy, RA; O'Connor, M; Rembold, CM; Wardle, RL | 1 |
| Arai, H; Chun, TH; Doi, K; Fukunaga, Y; Hosoya, T; Inoue, M; Itoh, H; Masatsugu, K; Mukoyama, M; Nakao, K; Saito, T; Sakaguchi, S; Sawada, N; Tanaka, T; Tojo, K; Yamashita, J | 1 |
| Argibay, J; Hoebeke, J; Nascimento, JH; Peineau, N; Sallé, L | 1 |
| Hartell, NA; Jacoby, S; Sims, RE | 1 |
| Jacobson, KL; Ott, SM; Singh, JC; Watson, EL | 1 |
| Brüne, B; Gantner, F; Sandau, KB | 1 |
| Bers, DM; Katoh, H; Ziolo, MT | 1 |
| Hou, L; Wang, X | 1 |
| Craig, EC; Haynes-Johnson, D; Kraft, P; Liu, X; Qiu, Y | 1 |
| Makhlouf, GM; Murthy, KS; Zhou, H | 1 |
| Adolfsson, PI; Ahlstrand, C; Svensson, SP; Varenhorst, E | 1 |
| Braiman, A; Priel, Z; Zagoory, O | 1 |
| Fujita, M; Furukawa, H; Horiuchi, H; Ishikawa, H; Jin, MB; Magata, S; Masuko, H; Ogata, K; Ogata, T; Shimamura, T; Suzuki, T; Taniguchi, M; Todo, S | 1 |
| Andreasen, D; Friis, UG; Hansen, PB; Jensen, BL; Sethi, S; Skøtt, O | 1 |
| Frölich, JC; Heuer, O; Jonas, U; Machtens, SA; Stief, CG; Tsikas, D; Uckert, S | 1 |
| Ciani, E; Contestabile, A; Virgili, M | 1 |
| Brunton, LL; Gustafsson, AB | 1 |
| Mann, GE; Morgan, AJ; Pearson, JD; Sobrevia, L; Steinert, JR; Sugden, D; Wheeler-Jones, CP; Wyatt, AW | 1 |
| Chih, TT; Chiu, HF; Hsian, YM; Tseng, CH; Wu, MJ; Wu, YC | 1 |
| Barman, SA; Han, G; White, RE; Zhu, S | 1 |
| Libersan, D; Merhi, Y; Rousseau, G | 1 |
| Isaacson, JS; Murphy, GJ | 1 |
| Ckert, S; Frlich, Jr; Jonas, U; Machtens, S; Stief, CG; Tsikas, D | 1 |
| Chen, YH; LaPolt, PS; Ngo, A; Tafoya, M | 1 |
| Naik, JS; Walker, BR | 1 |
| Kelly, C; Sawmiller, DR; Tarpey, SB; Thompson, WJ; Townsley, MI | 1 |
| Delbecque, JP; Gautron, F; Manière, G; Vanhems, E | 1 |
| Belinsky, MG; Chen, ZS; Guo, Y; Hopper-Borge, E; Kotova, E; Kruh, GD; Lee, K | 1 |
| Channer, KS; English, KM; Jones, RD; Jones, TH; Morton, IE; Roberts, SA; Ruban, LN | 1 |
| Andric, SA; Kostic, TS; Stojilkovic, SS | 1 |
| Diamond, J; Sandirasegarane, L | 1 |
| Brading, AF; Hashitani, H; Suzuki, H | 1 |
| Ikuta, T; Inoue, A; Kuroyanagi, Y; Moi, P; Terui, K | 1 |
| Huang, W; Hui, Y; Ma, J; Wang, L; Yuan, M | 1 |
| Puggina, E; Sellitti, D | 1 |
| Baughman, VL; Gavrilyuk, V; Pelligrino, DA; Wolde, HM; Xu, HL | 1 |
| Dryer, SE; Ko, GY; Ko, M | 1 |
| Kaneda, T; Nakajyo, S; Shimizu, K; Urakawa, N | 1 |
| Felipo, V; Llansola, M; Montoliu, C; Sánchez-Pérez, AM | 1 |
| Barrett, KE; Childs, D; Chow, JY; Dong, H; Hogan, DL; Isenberg, JI; Pratha, VS; Sellers, ZM; Smith, AJ | 1 |
| Levine, JD; Parada, CA; Reichling, DB | 1 |
| Huo, L; Lei, L; Sun, Q; Tao, Y; Wang, F; Xia, G; Xie, H; Zhang, M; Zhou, B | 1 |
| Hirst, GD; Ito, Y; Teramoto, N; Zhu, HL | 1 |
| Elmedal Laursen, B; Mulvany, MJ; Simonsen, U | 1 |
| Eaton, MS; Kim, K; Weiss, LM | 1 |
| Anne Marie, V; Carine, de V; Christine, D; De Vriese, C; Delogne-Desnoeck, J; Delporte, C; Graff, G; Guy, G; Josiane, DD; Lambot, N; Lebrun, P; Meuris, S; Nathalie, L; Philippe, L; Sylvain, M; Vanbellinghen, AM | 1 |
| Alonso, R; Díaz, M; Guelmes, P; Marín, R; Morales, A | 1 |
| Batts, TW; Murphy, RA; Rembold, CM; Walker, JS | 1 |
| Antunes, E; Baracat, JS; Claudino, MA; De Nucci, G; Priviero, FB; Teixeira, CE; Webb, RC | 1 |
| Canová, NK; Farghali, H; Kameníková, L; Kmonícková, E; Lincová, D | 1 |
| Berg, KM; Evans, MC; Miner, AS; Porter, M; Ratz, PH; Ward, KR | 1 |
| Benedito, S; García-Sacristán, A; Hernández, M; Prieto, D; Recio, P; Rivera, L; Villalba, N | 1 |
| Douglas Watson, R; Han, DW; Patel, N | 1 |
| Chigogidze, T; Jonas, U; Kediia, G; Kediia, M; Managadze, LG; Truss, MC; Uckert, S | 1 |
| Felipo, V; Llansola, M; Sánchez-Pérez, AM | 1 |
| Andric, SA; Gonzalez-Iglesias, AE; Jiang, Y; Kretschmannova, K; Stojilkovic, SS; Tomić, M; Zemkova, H | 1 |
| Dover, GJ; Keefer, JR; Mays, A; Purvis, SH; Schneidereith, TA; Smith, KD | 1 |
| Gupte, SA; Rabbani, G; Sarabu, MR; Vijay, V | 1 |
| Abbate, R; Cinotti, S; Gensini, GF; Geppetti, P; Masotti, G; Patacchini, R; Trevisani, M; Zagli, G | 1 |
| Bachmann, O; Chen, M; Cinar, A; Kocher, O; Manns, M; Riederer, B; Seidler, U; Wiemann, M | 1 |
| Fleischmann, BK; Hescheler, J; Reppel, M; Reuter, H; Sasse, P; Schunkert, H | 1 |
| Bilodeau, ML; Hamm, HE | 1 |
| Je, HD; Lee, YP; Shin, CY; Sohn, UD; Song, HJ | 1 |
| Burrell, HE; Durham, B; Fraser, WD; Gallagher, JA; McCreavy, DT; Mehat, S; Sharpe, GR; Simpson, AW | 1 |
| Chen, JF; Hong, X; Qu, JH; Song, L; Sun, H; Wang, SL; Wang, XR; Wang, YB; Xu, XL | 1 |
| Kim, SH; La, HO; Lee, DK; Min, YS; Park, SY; Ryu, JS; Shin, CY; Sohn, UD; Song, HJ; Youm, JH | 1 |
| Alvarez, E; Cairrão, E; Morgado, M; Santos-Silva, AJ; Verde, I | 1 |
| Adyshev, D; Mirzapoiazova, T; Pearse, DB; Renné, T; Rentsendorj, O; Servinsky, LE; Verin, AD | 1 |
| Mühlbauer, E; Peschke, E; Stumpf, I | 1 |
| Teramoto, N; Zhu, HL | 1 |
| Chen, Q; Dong, C; Frasch, T; Hill, SM; Lai, L; Mao, L; Rowan, B; Yuan, L | 1 |
| Sosroseno, W; Sugiatno, E | 1 |
| Dong, H; Liu, X; Tuo, B; Wang, X; Wen, G; Zhang, Y | 1 |
| Bicker, G; Stern, M; Tegenge, MA | 1 |
| Goy, D; Gummersbach, C; Hemmrich, K; Kröncke, KD; Pallua, N; Paul, NE; Suschek, CV | 1 |
| Hong, Y; Hui, L; Jingjing, Z; Nong, Z; Qi, C; Yuan, H | 1 |
| Biel, M; Leinders-Zufall, T; Pyrski, M; Schmid, A; Zufall, F | 1 |
| Laychock, SG; You, H | 1 |
| Birowo, P; Kedia, GT; Kuczyk, MA; Rahardjo, D; Sandner, P; Scheller, F; Sonnenberg, JE; Thon, WF; Uckert, S | 1 |
| Duszyk, M; Gong, X; McCarthy, J; Nahirney, D; Radomski, M | 1 |
| Bombarda, G; Fazan, R; Sabino, JP; Salgado, HC; Salgado, MC; Silva, CA | 1 |
| Chatagnon, G; Desfontis, JC; Gogny, M; Kabbesh, N; Mallem, MY; Noireaud, J; Thorin, C | 1 |
| Cho, KW; Kim, SH; Kim, SM; Kim, SY; Kim, SZ | 1 |
| Kretschmannova, K; Stojilkovic, SS; Stratakis, CA; Tomić, M | 1 |
| Blouquit-Laye, S; Braun, C; Chinet, T; Dannhoffer, L; Dinh-Xuan, AT; Sage, E | 1 |
| Borgognone, A; Pulcinelli, FM | 1 |
| Andric, N; Dakic, V; Fa, S; Hrubik, J; Kaisarevic, S; Kovacevic, R; Pogrmic-Majkic, K; Stojilkovic, SS | 1 |
| Chatagnon, G; Desfontis, JC; Gogny, M; Kabbesh, N; Mallem, MY; Noireaud, J | 1 |
| Jia, J; Li, W; Qin, C; Sun, C; Wang, B; Zhang, C | 1 |
| Doseyici, S; Erbay, E; Mehmetoglu, I; Toker, A; Yerlikaya, FH | 1 |
| Bae, H; Bang, H; Kim, JH; Kim, K; Kim, T; Ko, JH; Lee, HJ; Lim, I | 1 |
| Cabral, PH; de Morais Campos, R; do Nascimento, NR; Fonteles, MC; Leal Cardoso, JH; Santos, CF | 1 |
| Cascalheira, JF; Sebastião, AM; Serpa, A | 1 |
| Fujii, H; Hagiwara, H; Iizuka, M; Nakakura, T; Okazaki, T; Okinaga, H; Susa, T; Tamamori-Adachi, M; Tanaka, Y; Uchida, K | 1 |
| Anoopkumar-Dukie, S; Grant, GD; Hempenstall, A; Johnson, PJ | 1 |
| Fernández-Fernández, D; Kroker, KS; Rosenbrock, H | 1 |
| Campen, KA; Clark, ZL; McNatty, KP; Olds, MA; Pitman, JL | 1 |
| Berczeli, O; Ding, C; Facskó, A; Hegyi, P; Katona, M; Orvos, P; Rakonczay, Z; Rárosi, F; Tóth-Molnár, E; Venglovecz, V; Vizvári, E | 1 |
| Aue, A; Dünnes, S; Friebe, A; Groneberg, D; Groneberg, K; Nikolaev, V; Voussen, B | 1 |
| Alvarez, DF; Annamdevula, N; Audia, JP; Britain, A; Dunbar, G; Hardy, KS; Housley, N; Leavesley, S; Renema, P; Rich, T; Spadafora, D | 1 |
2 review(s) available for colforsin and cyclic gmp
| Article | Year |
|---|---|
Positive inotropic agents.
Topics: Action Potentials; Animals; Calcium; Cardiotonic Agents; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Dopamine; Humans; Ionophores; Phosphodiesterase Inhibitors; Sodium-Potassium-Exchanging ATPase; Sympathomimetics; Ubiquinone | 1984 |
Dependence of the excitability of pituitary cells on cyclic nucleotides.
Topics: Action Potentials; Adenylyl Cyclases; Animals; Calcium Signaling; Colforsin; Cyclic AMP; Cyclic GMP; Endocrine Cells; Guanylate Cyclase; Humans; Ion Channels; Models, Animal; Models, Biological; Pituitary Gland; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction | 2012 |
393 other study(ies) available for colforsin and cyclic gmp
| Article | Year |
|---|---|
Multiple intracellular signaling pathways of the neuropeptide substance P receptor.
Topics: Animals; Calcium; Cells, Cultured; Colforsin; Cyclic GMP; Fura-2; Iodine Radioisotopes; Protein Kinase C; Rats; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Signal Transduction; Substance P; Transfection | 1992 |
Inhibition of proliferation, but not of Ca2+ mobilization, by cyclic AMP and GMP in rabbit aortic smooth-muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Angiotensin II; Animals; Aorta; Calcium; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Muscle, Smooth; Platelet-Derived Growth Factor; Rabbits; Serotonin | 1992 |
Synergistic action of cyclic GMP on catecholamine-induced chloride current in guinea-pig ventricular cells.
Topics: Animals; Catecholamines; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Heart Ventricles; Histamine; Ion Channels; Isoproterenol; Membrane Potentials; Milrinone; Myocardium; Pyridones | 1992 |
Bradykinin inhibition of cyclic AMP accumulation in D384 astrocytoma cells. Evidence against a role of cyclic GMP.
Topics: 1-Methyl-3-isobutylxanthine; Arginine; Astrocytoma; Bradykinin; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Hydroxylamine; Hydroxylamines; Kinetics; NG-Nitroarginine Methyl Ester; Nitroprusside; Pyrrolidinones; Rolipram; Tumor Cells, Cultured | 1992 |
Production and secretion of nerve growth factor by clonal striated muscle cell line, G8-1.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Bucladesine; Calcimycin; Cell Line; Clone Cells; Cloning, Molecular; Colforsin; Culture Media, Conditioned; Cyclic AMP; Cyclic GMP; DNA; Electrophoresis, Polyacrylamide Gel; Gene Library; Kinetics; Mice; Molecular Sequence Data; Molecular Weight; Muscles; Nerve Growth Factors; Oligodeoxyribonucleotides; Poly A; Polymerase Chain Reaction; RNA; RNA, Messenger; Submandibular Gland; Veratridine | 1992 |
Direct evidence for cross-activation of cGMP-dependent protein kinase by cAMP in pig coronary arteries.
Topics: Animals; Arteries; Atrial Natriuretic Factor; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Enzyme Activation; In Vitro Techniques; Isoproterenol; Nitroprusside; Protein Kinases; Second Messenger Systems; Swine | 1992 |
Cholera toxin augments the release of endothelium-derived relaxing factor evoked by bradykinin and the calcium ionophore A23187.
Topics: Adenosine Diphosphate; Animals; Bradykinin; Calcimycin; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Nitric Oxide; Swine | 1992 |
Intracellular cyclic AMP produces effects opposite to those of cyclic GMP and calcium on shape and motility of neuroblastoma cells.
Topics: Bucladesine; Calcium; Cell Movement; Colforsin; Cyclic AMP; Cyclic GMP; Electric Stimulation; Inositol Phosphates; Microinjections; Neuroblastoma; Neurons; Tumor Cells, Cultured; Video Recording | 1992 |
Hormonal activation of the cGMP-inhibited low-Km cyclic AMP phosphodiesterase of rat adipocytes from different sites: influence of ovariectomy.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Female; Insulin; Isoproterenol; Ovariectomy; Ovary; Protein Kinases; Rats; Rats, Inbred Strains; Subcellular Fractions | 1992 |
Impaired cyclic nucleotide-mediated vasorelaxation may contribute to closure of the human umbilical artery after birth.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Labor, Obstetric; Male; Nitroprusside; Pregnancy; Rats; Rats, Wistar; Serotonin; Umbilical Arteries; Vasodilation | 1992 |
Effect of vasodilators, including nitric oxide, on the release of cGMP and cAMP in the isolated perfused rat kidney.
Topics: Acetylcholine; Animals; Atrial Natriuretic Factor; Citrulline; Colforsin; Cyclic AMP; Cyclic GMP; Epoprostenol; Kidney; Male; Methoxamine; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Rats; Rats, Wistar; Serotonin; Vasoconstriction; Vasodilation; Vasodilator Agents | 1992 |
Nitric oxide formation caused by Ca2+ release from internal stores in neuronal cell line is enhanced by cyclic AMP.
Topics: Animals; Arginine; Bradykinin; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Mice; Neurons; Nitric Oxide; Rats; Serotonin; Tumor Cells, Cultured | 1992 |
Phosphoinositide and calcium signalling responses in smooth muscle cells: comparison between lipoproteins, Ang II, and PDGF.
Topics: Angiotensin II; Calcium; Colforsin; Cyclic GMP; Cytosol; Humans; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Muscle, Smooth, Vascular; Phosphatidylinositols; Platelet-Derived Growth Factor; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1992 |
On the role of bradykinin in secretion from vascular endothelial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Bradykinin; Calcium; Calcium Channel Blockers; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Hindlimb; Kinetics; Male; Nitroprusside; Perfusion; Rats; Rats, Wistar; Receptors, Bradykinin; Receptors, Neurotransmitter; Tissue Plasminogen Activator; von Willebrand Factor | 1992 |
Modulation of barrier function of bovine aortic and pulmonary artery endothelial cells: dissociation from cytosolic calcium content.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Calcium; Capillary Permeability; Cattle; Colforsin; Cyclic GMP; Cytosol; Endothelium, Vascular; Peptide Fragments; Pulmonary Artery; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate; Thrombin | 1992 |
Novel signal transduction pathway mediating endothelium-dependent beta-adrenoceptor vasorelaxation in rat thoracic aorta.
Topics: Albuterol; Animals; Aorta, Thoracic; Arginine; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Nitroprusside; Norepinephrine; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction | 1992 |
Assessment of the role of cyclic nucleotides in allatostatin-induced inhibition of juvenile hormone biosynthesis in Diploptera punctata.
Topics: Animals; Cockroaches; Colforsin; Corpora Allata; Cyclic AMP; Cyclic GMP; Depression, Chemical; Female; Juvenile Hormones; Neuropeptides; Second Messenger Systems; Sexual Behavior, Animal | 1992 |
Guanylate cyclase inhibitors: effect on inhibitory junction potentials in esophageal smooth muscle.
Topics: Animals; Colforsin; Cyclic GMP; Electric Stimulation; Electrophysiology; Esophagus; Female; Guanylate Cyclase; Male; Membrane Potentials; Muscle, Smooth; Nervous System Physiological Phenomena; Neural Inhibition; Neuromuscular Junction; Nitroprusside; Opossums | 1992 |
Adrenergic mechanisms associated with the movement of platelets in iridophores from the freshwater goby, Odontobutis obscura.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Platelets; Cell Movement; Cells, Cultured; Chromatophores; Colforsin; Cyclic GMP; Fishes; Isoproterenol; Norepinephrine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1992 |
Nitric oxide but not prostacyclin is an autocrine endothelial mediator.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Endothelium, Vascular; Epoprostenol; Iloprost; Nitric Oxide; omega-N-Methylarginine; Second Messenger Systems; Swine | 1992 |
Agents that affect calcium influx can change cyclic nucleotide levels in cultured chick pineal cells.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Kinetics; Nitrendipine; Pineal Gland | 1992 |
Cyclic nucleotides mediate an odor-evoked potassium conductance in lobster olfactory receptor cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Electric Conductivity; Nephropidae; Odorants; Olfactory Pathways; Potassium; Signal Transduction | 1992 |
Positively cooperative cAMP phosphodiesterase attenuates cellular cAMP responses.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Epinephrine; Tumor Cells, Cultured | 1992 |
cAMP promotes branching of laminin-induced neuronal processes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Calcium; Cell Differentiation; Colforsin; Cyclic AMP; Cyclic GMP; Fluorescent Antibody Technique; In Vitro Techniques; Intermediate Filaments; Laminin; Membrane Proteins; Neurons; Rats; Signal Transduction; Sodium; Synaptophysin; Tumor Cells, Cultured | 1991 |
Oxygen-dependent erythropoietin production by the isolated perfused rat kidney.
Topics: Animals; Calmodulin; Colforsin; Cyclic GMP; Erythropoietin; Imidazoles; Kidney; Kinetics; Male; Oxygen; Rats; Second Messenger Systems; Sulfonamides; Vascular Resistance | 1991 |
Segmental heterogeneity of the rat colon in the response to activators of secretion on the cAMP-, the cGMP- and the Ca(2+)-pathway.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Carbachol; Chlorides; Colforsin; Colon; Cyclic AMP; Cyclic GMP; Epithelium; Female; Humans; In Vitro Techniques; Prostaglandins; Rats; Rats, Inbred Strains; Sodium; Tetrodotoxin | 1991 |
Effects of clonidine and other imidazole-receptor binding agents on second messenger systems and calcium influx in bovine adrenal chromaffin cells.
Topics: Adrenal Glands; Animals; Calcium; Cattle; Cells, Cultured; Clonidine; Colforsin; Cyclic AMP; Cyclic GMP; Inositol Phosphates; Receptors, Drug; Second Messenger Systems; Signal Transduction | 1991 |
Collagen-induced exposure of anionic phospholipid in platelets and platelet-derived microparticles.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine; Affinity Labels; Alkaloids; Anions; Annexin A5; Binding Sites; Blood Platelets; Bucladesine; Calcimycin; Calcium-Binding Proteins; Colforsin; Collagen; Cyclic GMP; Factor Va; Flow Cytometry; Humans; Nitroprusside; Phospholipids; Platelet Aggregation; Pregnancy Proteins; Signal Transduction; Staurosporine; Theophylline; Thromboplastin | 1991 |
Immunocytochemical localization of cAMP and cGMP in cells of the rat carotid body following natural and pharmacological stimulation.
Topics: Animals; Atrial Natriuretic Factor; Carotid Body; Cell Hypoxia; Colforsin; Cyclic AMP; Cyclic GMP; Female; Immunohistochemistry; Male; Nitroprusside; Potassium Chloride; Rats; Second Messenger Systems; Signal Transduction | 1991 |
Modulation of agonist-induced calcium mobilisation in bovine aortic endothelial cells by phorbol myristate acetate and cyclic AMP but not cyclic GMP.
Topics: Animals; Aorta; Arginine; Bradykinin; Calcium; Calcium Channel Agonists; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Isoproterenol; Nitroarginine; Nitroprusside; Tetradecanoylphorbol Acetate; Thrombin | 1991 |
Role of cyclic nucleotides in the control of hepatic autophagy.
Topics: Animals; Atrial Natriuretic Factor; Autophagy; Bucladesine; Colforsin; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; In Vitro Techniques; Liver; Male; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Proteins; Rats | 1991 |
Functional antagonism in rabbit pulmonary veins contracted by endothelin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Endothelins; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Phenylephrine; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Veins; Rabbits; Receptors, Cell Surface | 1991 |
Potentiation by cyclic GMP of beta-adrenergic effect on Ca2+ current in guinea-pig ventricular cells.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Dialysis; Drug Synergism; Guinea Pigs; Heart; Isoproterenol; Myocardium; Protein Kinases | 1991 |
Catecholaminergic traits of chick sympathetic neurons may be differentially regulated by a cGMP-dependent pathway.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Animals; Carbon Radioisotopes; Catecholamines; Chick Embryo; Colforsin; Cyclic GMP; Inosine; Neurons; Neurotransmitter Agents; Nitroprusside; Purines; Sympathetic Nervous System; Tritium | 1991 |
Cyclic nucleotide content of the rat anococcygeus during relaxations induced by drugs or by non-adrenergic, non-cholinergic field stimulation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Autonomic Nervous System; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Electric Stimulation; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Purinones; Rats; Rats, Inbred Strains | 1991 |
Stimulatory effects of brain natriuretic peptide on cyclic GMP accumulation and tyrosine hydroxylase activity in cultured bovine adrenal medullary cells.
Topics: Adrenal Medulla; Animals; Atrial Natriuretic Factor; Calcium; Cattle; Cell Membrane Permeability; Cells, Cultured; Colforsin; Cyclic GMP; Digitonin; Extracellular Space; Kinetics; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Phosphorylation; Sodium; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tyrosine 3-Monooxygenase | 1991 |
Implication of cyclic AMP in the positive inotropic effects of cyclic GMP-inhibited cyclic AMP phosphodiesterase inhibitors on guinea pig isolated left atria.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Chloride; Cardiotonic Agents; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Milrinone; Myocardial Contraction; Myocardium; Protoveratrines; Pyrazines; Pyridones; Sodium | 1990 |
17 beta-estradiol depolarization of hypothalamic neurons is mediated by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Drug Implants; Electric Conductivity; Estradiol; Female; Guinea Pigs; Hypothalamus; Imidazoles; Membrane Potentials; Neurons; Ovariectomy; Potassium; Theophylline | 1990 |
Regulation of cAMP metabolism in mouse parotid gland by cGMP and calcium.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Calcium; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Hydroxylamine; Hydroxylamines; Mice; Parotid Gland | 1990 |
Effects of peptides of the secretin-glucagon family and cyclic nucleotides on tyrosine hydroxylase activity in sympathetic nerve endings.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Drug Synergism; Heart Ventricles; Male; Nerve Endings; Nitroprusside; Protein Kinase C; Rats; Rats, Inbred Strains; Second Messenger Systems; Secretin; Sympathetic Nervous System; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide | 1991 |
Current recording from sensory cilia of olfactory receptor cells in situ. I. The neuronal response to cyclic nucleotides.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Animals; Caffeine; Cilia; Colforsin; Cyclic AMP; Cyclic GMP; Electrophysiology; In Vitro Techniques; Nasal Mucosa; Phosphodiesterase Inhibitors; Rana esculenta; Rana ridibunda; Sensory Receptor Cells; Smell | 1991 |
Endothelium reduces DNA synthesis in isolated arteries.
Topics: Acetylcholine; Animals; Atrial Natriuretic Factor; Bromodeoxyuridine; Colforsin; Culture Techniques; Cyclic AMP; Cyclic GMP; Dinoprostone; DNA; Endothelium, Vascular; Iloprost; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Potassium; Rats; Rats, Inbred WKY; Renal Artery; Sympathectomy | 1991 |
Inhibition of the chick pineal rhythm in rate of thymidine incorporation by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Chickens; Colforsin; Cyclic AMP; Cyclic GMP; Periodicity; Phosphodiesterase Inhibitors; Pineal Gland; Thymidine | 1991 |
Evaluating atrial natriuretic peptide-induced cGMP production by particulate guanylyl cyclase stimulation in vitro and in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Adrenal Cortex; Animals; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Guanylate Cyclase; Humans; Kidney Glomerulus; Kinetics; Muscle, Smooth, Vascular; Nitroprusside; Radioimmunoassay; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface | 1991 |
The possibility of participation of different protein kinases in the regulation of degradation of Glp6[125I]Tyr8SP6-11 with different endopeptidases in subcellular fractions of rat brain.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Brain; Cell Nucleus; Cerebral Cortex; Colforsin; Cyclic AMP; Cyclic GMP; Endopeptidases; Hippocampus; Neurotransmitter Agents; Peptide Fragments; Protease Inhibitors; Protein Kinases; Pyrrolidonecarboxylic Acid; Rats; Second Messenger Systems; Subcellular Fractions; Substance P; Synaptosomes; Tetradecanoylphorbol Acetate | 1991 |
Relaxant effects of alpha-human atrial natriuretic peptide on venous smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Female; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Peptide Fragments; Purinones; Saphenous Vein; Splenic Artery; Vasodilation | 1991 |
Regulation by forskolin of cyclic AMP phosphodiesterase and protein kinase C activity in LLC-PK1 cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alkaloids; Animals; Cells, Cultured; Colforsin; Cyclic GMP; Galactose; Macaca mulatta; Pregnenolone; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Control of HCO3-dependent exchangers by cyclic nucleotides in vascular smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta; Bicarbonates; Biological Transport, Active; Colforsin; Cyclic AMP; Cyclic GMP; Fluorescent Dyes; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Exchange; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred Strains | 1991 |
Effects of 8-bromo-cyclic GMP on slow channel mediated action potentials of 3-days-old embryonic chick ventricle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Chick Embryo; Colforsin; Cyclic GMP; Heart Ventricles; Ion Channels; Isoproterenol; Ventricular Function | 1991 |
Cyclic AMP mimics, but does not mediate, interleukin-1- and tumour-necrosis-factor-stimulated phospholipase A2 secretion from rat renal mesangial cells.
Topics: Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Drug Synergism; Glomerular Mesangium; Hydrolysis; Interleukin-1; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Prostaglandin Antagonists; Protein Kinase C; Rats; Tumor Necrosis Factor-alpha | 1991 |
See-saw signal processing: reciprocal effects of stimulus deprivation on vasoactive intestinal peptide-stimulated adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate accumulation in rat pinealocytes.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Light; Male; Phenylephrine; Pineal Gland; Potassium; Rats; Rats, Inbred Strains; Sensory Deprivation; Signal Transduction; Sympathomimetics; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1991 |
Atriopeptin stimulates chloride secretion in cultured shark rectal gland cells.
Topics: 2-Chloroadenosine; Animals; Atrial Natriuretic Factor; Bumetanide; Cells, Cultured; Chlorides; Colforsin; Cyclic GMP; Dogfish; Electric Conductivity; Epithelium; Female; Ionomycin; Kinetics; Male; Rectum; Salt Gland; Vasoactive Intestinal Peptide | 1991 |
Stimulants of ileal salt transport in neuroendocrine system of the desert locust.
Topics: Animals; Biological Transport; Cell Membrane Permeability; Central Nervous System; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Ganglia; Grasshoppers; Ileum; Insect Hormones; Neurosecretory Systems; Neurotransmitter Agents; Peptide Hydrolases; Potassium Chloride; Proteins; Rectum; Second Messenger Systems; Temperature; Theophylline; Time Factors; Tissue Extracts | 1990 |
Nerve growth factor-induced rapid reorganization of microfilaments in PC12 cells: possible roles of different second messenger systems.
Topics: Actin Cytoskeleton; Actins; Adrenal Gland Neoplasms; Animals; Axons; Bucladesine; Calcium; Colchicine; Colforsin; Cyclic AMP; Cyclic GMP; Cytochalasin B; Cytoskeleton; Dibutyryl Cyclic GMP; Kinetics; Methyltransferases; Nerve Growth Factors; Pheochromocytoma; Phosphatidylinositols; Rats; Second Messenger Systems; Tumor Cells, Cultured | 1990 |
Immunocytology on microwave-fixed cells reveals rapid and agonist-specific changes in subcellular accumulation patterns for cAMP or cGMP.
Topics: Animals; Atrial Natriuretic Factor; Calcitonin; Cell Line; Cell-Free System; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Fibroblasts; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Humans; Immunoenzyme Techniques; Isoproterenol; Mice; Microwaves; Nitroprusside; Skin; Subcellular Fractions; Thiocyanates | 1990 |
Pig aortic endothelial-cell cyclic nucleotide phosphodiesterases. Use of phosphodiesterase inhibitors to evaluate their roles in regulating cyclic nucleotide levels in intact cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta; Calcium; Cells, Cultured; Chromatography, Ion Exchange; Colforsin; Cyclic AMP; Cyclic GMP; Dipyridamole; Endothelium, Vascular; Isoquinolines; Kinetics; Purinones; Pyrazines; Pyrrolidinones; Rolipram; Swine; Tetrahydroisoquinolines | 1990 |
cGMP-dependent protein kinase mediates the reduction of Ca2+ by cAMP in vascular smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Electrophoresis, Polyacrylamide Gel; Isoenzymes; Kinetics; Male; Molecular Weight; Muscle, Smooth, Vascular; Protein Kinases; Rats; Rats, Inbred Strains | 1990 |
Partial characterization of cyclic AMP-dependent protein kinases in guinea-pig lung employing the synthetic heptapeptide substrate, kemptide. In vitro sensitivity of the soluble enzyme to isoprenaline, forskolin, methacholine and leukotriene D4.
Topics: Adenosine Triphosphate; Animals; Carrier Proteins; Chromatography, DEAE-Cellulose; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Guinea Pigs; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoenzymes; Isoproterenol; Lung; Magnesium; Male; Methacholine Chloride; Methacholine Compounds; Oligopeptides; Protein Kinase Inhibitors; Protein Kinases; Solubility; SRS-A | 1990 |
Post-transcriptional regulation of cAMP-dependent protein kinase activity by cAMP in GH3 pituitary tumor cells. Evidence for increased degradation of catalytic subunit in the presence of cAMP.
Topics: Animals; Bucladesine; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Gene Expression Regulation, Enzymologic; Kinetics; Macromolecular Substances; Pituitary Neoplasms; Protein Kinases; Protein Processing, Post-Translational; RNA, Messenger | 1990 |
VIP-mediated increase in cAMP prevents tetrodotoxin-induced retinal ganglion cell death in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Survival; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Retina; Retinal Ganglion Cells; Secretin; Tetrodotoxin; Vasoactive Intestinal Peptide | 1990 |
Neuropeptide Y stimulation of myosin light chain phosphorylation in cultured aortic smooth muscle cells.
Topics: Adenylate Cyclase Toxin; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; In Vitro Techniques; Inositol Phosphates; Muscle Contraction; Muscle, Smooth, Vascular; Myosins; Neuropeptide Y; Pertussis Toxin; Phosphorylation; Protein Kinase C; Signal Transduction; Swine; Virulence Factors, Bordetella | 1990 |
Epithelium, contractile tone, and responses to relaxing agonists in canine bronchi.
Topics: Acetylcholine; Animals; Bronchi; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Epithelium; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitroprusside; Serotonin | 1990 |
cAMP mediates IL-1-induced lymphocyte penetration through endothelial monolayers.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Endothelium, Vascular; Gene Expression; In Vitro Techniques; Inflammation; Interleukin-1; Isoquinolines; Lymphocytes; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Signal Transduction; Sulfonamides | 1990 |
Histones inhibit human chorionic gonadotrophin-stimulated but not atrial peptide-stimulated testosterone production and cyclic nucleotide formation by isolated mouse Leydig cells.
Topics: Animals; Atrial Natriuretic Factor; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Histones; Humans; Iodine Radioisotopes; Leydig Cells; Male; Mice; Peptide Fragments; Testosterone | 1990 |
Role of adenosine 3',5'-cyclic monophosphate in adrenoceptor-mediated control of 3H-noradrenaline secretion in guinea-pig ileum myenteric nerve terminals.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Ileum; In Vitro Techniques; Isoproterenol; Male; Myenteric Plexus; Nerve Endings; Nicotinic Acids; Norepinephrine; Phosphodiesterase Inhibitors; Propranolol; Receptors, Adrenergic; Yohimbine | 1985 |
Augmentation of cholinergic-mediated amylase release by forskolin in mouse parotid gland.
Topics: Amylases; Animals; Calcimycin; Calcium; Carbachol; Colforsin; Cyclic GMP; Drug Synergism; Guanosine; Hydroxylamine; Hydroxylamines; Isoproterenol; Mice; Nitroprusside; Parasympathomimetics; Parotid Gland | 1985 |
Atrial natriuretic factor does not affect basal, forskolin- and CRF-stimulated adenylate cyclase activity, cAMP formation or ACTH secretion, but does stimulate cGMP synthesis in anterior pituitary.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Atrial Natriuretic Factor; Cell Line; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic GMP; Growth Hormone; Kinetics; Mice; Nifedipine; Pituitary Gland, Anterior; Potassium Chloride; Tetradecanoylphorbol Acetate | 1986 |
Role of cAMP in modulating intrafollicular progesterone levels and oocyte maturation in amphibians (Rana pipiens).
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Colforsin; Cyclic AMP; Cyclic GMP; Drug Synergism; Female; Oocytes; Oogenesis; Ovary; Pituitary Hormones; Progesterone; Rana pipiens | 1986 |
The phorbol ester induced atrial natriuretic peptide secretion is stimulated by forskolin and Bay K8644 and inhibited by 8-bromo-cyclic GMP.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atrial Natriuretic Factor; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Depression, Chemical; Perfusion; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1986 |
Parathyroid hormone-induced changes in cyclic nucleotide levels during relaxation of the rabbit [correction of rat] aorta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Parathyroid Hormone; Rabbits | 1987 |
Potentiation of cholinergic responses in mouse parotid gland by a cAMP dependent mechanism involves cGMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Mice; Parasympathetic Nervous System; Parotid Gland | 1987 |
Mechanism for amine modulation of the neurogenic Limulus heart: evidence for involvement of cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biogenic Amines; Colforsin; Cyclic AMP; Cyclic GMP; Dopamine; Heart; Horseshoe Crabs; Myocardium; Octopamine | 1987 |
On the role of cyclic nucleotides in the pathogenesis of human atherosclerosis.
Topics: 1-Methyl-3-isobutylxanthine; Aorta; Arteriosclerosis; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Humans; Lipid Metabolism; Organ Culture Techniques | 1987 |
Egg-laying hormone, serotonin, and cyclic nucleotide modulation of ionic currents in the identified motoneuron B16 of Aplysia.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aplysia; Colforsin; Cyclic GMP; Electrophysiology; Invertebrate Hormones; Membrane Potentials; Motor Neurons; Serotonin | 1988 |
The effect of parathyroid hormone and atrial natriuretic peptide on cyclic nucleotides production and proliferation of avian epiphyseal growth plate chondroprogenitor cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenocorticotropic Hormone; Animals; Atrial Natriuretic Factor; Cartilage; Cells, Cultured; Chick Embryo; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Growth Plate; Kinetics; Parathyroid Hormone; Peptide Fragments; Prostaglandins E | 1988 |
Interaction of forskolin with the effect of atropine on [3H]acetylcholine secretion in guinea-pig ileum myenteric plexus.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Aminopyridines; Animals; Atropine; Colforsin; Cyclic GMP; Drug Interactions; Guinea Pigs; Ileum; In Vitro Techniques; Myenteric Plexus; Neuromuscular Junction | 1988 |
Inhibition of atrial natriuretic peptide secretion by forskolin in noncontracting cultured atrial myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Atrial Natriuretic Factor; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic GMP; Egtazic Acid; Muscle Contraction; Muscle, Smooth, Vascular; Protein Kinase C; Ryanodine; Sarcoplasmic Reticulum; Secretory Rate; Tetradecanoylphorbol Acetate | 1988 |
Excitation of locus coeruleus neurons by an adenosine 3',5'-cyclic monophosphate-activated inward current: extracellular and intracellular studies in rat brain slices.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Locus Coeruleus; Male; Membrane Potentials; Neurons; Rats; Reference Values; Theophylline | 1987 |
Attenuation of endotoxin-induced cytotoxicity and prostacyclin production in cultured bovine pulmonary artery endothelial cells by phosphodiesterase inhibition.
Topics: 1-Methyl-3-isobutylxanthine; 6-Ketoprostaglandin F1 alpha; Adenylyl Cyclases; Animals; Bucladesine; Cattle; Cell Survival; Cells, Cultured; Colforsin; Cyclic GMP; Endothelium, Vascular; Ferricyanides; L-Lactate Dehydrogenase; Lipopolysaccharides; Nitroprusside; Phosphodiesterase Inhibitors; Pulmonary Artery; Theophylline | 1988 |
Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. I. Studies with fluoride.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine Vasopressin; Arteries; Bucladesine; Calcium; Calcium Channels; Colforsin; Cyclic AMP; Cyclic GMP; GTP-Binding Proteins; In Vitro Techniques; Inositol Phosphates; Kinetics; Male; Muscle, Smooth, Vascular; Nifedipine; Potassium Chloride; Rats; Rats, Inbred Strains; Sodium Fluoride; Vasoconstriction; Verapamil | 1989 |
A study of the phasic response of arterioles of the guinea pig small intestine to prolonged exposure to norepinephrine.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arterioles; Clonidine; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Intestine, Small; Isoproterenol; Membrane Potentials; Norepinephrine; Oxidation-Reduction; Propranolol; Temperature; Theophylline; Vasoconstriction; Yohimbine | 1989 |
Second-messenger systems underlying amine and peptide actions on cardiac muscle in the horseshoe crab Limulus polyphemus.
Topics: 1-Methyl-3-isobutylxanthine; Amines; Animals; Catecholamines; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Epinephrine; Heart; Horseshoe Crabs; Myocardial Contraction; Neuropeptides; Norepinephrine; Oligopeptides; Peptides; Phorbol 12,13-Dibutyrate; Protein Kinase C; Second Messenger Systems | 1989 |
Cyclic nucleotide regulation of neurotransmission in guinea pig mesenteric artery.
Topics: Animals; Colforsin; Cyclic GMP; Electrophysiology; Guinea Pigs; Isoproterenol; Male; Membrane Potentials; Mesenteric Arteries; Nucleotides, Cyclic; Phorbol Esters; Protein Kinase C; Second Messenger Systems; Synaptic Transmission | 1989 |
Influence of stimulators and inhibitors of cyclic nucleotides on lower esophageal sphincter.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Electric Stimulation; Esophagogastric Junction; Ethylmaleimide; Female; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Nitroprusside; Opossums; Phosphodiesterase Inhibitors; Vasoactive Intestinal Peptide | 1989 |
Cytoplasmic Ca2+ is a primary determinant for myosin phosphorylation in smooth muscle cells.
Topics: Animals; Calcium; Cattle; Colforsin; Cyclic AMP; Cyclic GMP; Cytoplasm; Ethers; Histamine; In Vitro Techniques; Ionomycin; Muscle, Smooth; Myosins; Phosphorylation; Serotonin; Trachea | 1989 |
A comparison of vasodilator activity of agents activating cyclic nucleotides with those inhibiting their metabolism in rabbit isolated ear artery.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Ear, External; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Phosphodiesterase Inhibitors; Regional Blood Flow; Sympathetic Nervous System; Vasodilation | 1989 |
Forskolin stimulates pinealocyte cGMP accumulation. Dramatic potentiation by an alpha 1-adrenergic----[Ca2+]i mechanism involving protein kinase C.
Topics: Adenylyl Cyclases; Animals; Calcimycin; Calcium; Cations, Divalent; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Female; Phenylephrine; Pineal Gland; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate | 1989 |
Atrial natriuretic factor-induced egression of cyclic guanosine 3':5'-monophosphate in cultured vascular smooth muscle and endothelial cells.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Kinetics; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains | 1989 |
Direct regulation of smooth muscle contractile elements by second messengers.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Rats; Rats, Inbred WKY; Second Messenger Systems | 1989 |
Effects of defolliculation on membrane current responses of Xenopus oocytes.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cell Separation; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Dopamine; Female; In Vitro Techniques; Membrane Potentials; Microbial Collagenase; Norepinephrine; Oocytes; Ovarian Follicle; Potassium Channels; Vasoactive Intestinal Peptide; Xenopus laevis | 1989 |
Effects of hypoxia on cyclic nucleotide formation in rabbit carotid body in vitro.
Topics: Action Potentials; Animals; Carotid Body; Colforsin; Cyclic AMP; Cyclic GMP; Hypoxia; In Vitro Techniques; Nitroprusside; Rabbits; Second Messenger Systems; Synaptic Transmission | 1989 |
Co-regulation of tracheal tone by cyclic AMP- and cyclic GMP-dependent mechanisms.
Topics: Animals; Bucladesine; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle Contraction; Nitroprusside; Trachea | 1987 |
The role of cyclic nucleotides in atrial natriuretic peptide-mediated inhibition of aldosterone secretion.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Carbachol; Cattle; Colforsin; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Kinetics; Pertussis Toxin; Virulence Factors, Bordetella | 1988 |
Cyclic nucleotides depress action potentials in cultured aortic smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds | 1987 |
Effects of colforsin, trequinsin and isoprenaline on norepinephrine-induced contractions and cyclic nucleotide levels of isolated vascular tissue.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Platelet Aggregation Inhibitors; Rabbits; Tetrahydroisoquinolines | 1988 |
Regulation of the plasma membrane Ca2+ pump by cyclic nucleotides in cultured vascular smooth muscle cells.
Topics: Animals; Atrial Natriuretic Factor; Bucladesine; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cells, Cultured; Colforsin; Cyclic GMP; Hydrogen-Ion Concentration; Lanthanum; Magnesium; Male; Muscle, Smooth, Vascular; Nitroprusside; Nucleotides, Cyclic; Rats; Rats, Inbred WKY; Sodium | 1988 |
Photoendocrine transduction in cultured chick pineal cells. II. Effects of forskolin, 8-bromocyclic AMP, and 8-bromocyclic GMP on the melatonin rhythm.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Chickens; Circadian Rhythm; Colforsin; Cyclic GMP; Lighting; Melatonin; Pineal Gland | 1988 |
Effects of cilostazol, a selective cAMP phosphodiesterase inhibitor on the contraction of vascular smooth muscle.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aorta, Thoracic; Azoles; Bucladesine; Calcium; Cilostazol; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Tetrazoles; Vasodilator Agents | 1988 |
The effect of heat-stable Escherichia coli enterotoxin, theophylline and forskolin on cyclic nucleotide levels and mucosal surface (acid microclimate) pH in rat proximal jejunum in vivo.
Topics: Animals; Bacterial Toxins; Colforsin; Cyclic AMP; Cyclic GMP; Electric Conductivity; Enterotoxins; Escherichia coli Proteins; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Mucosa; Jejunum; Kinetics; Rats; Rats, Inbred Strains; Reference Values; Theophylline | 1988 |
Regulation of cytosolic calcium by cAMP and cGMP in freshly isolated smooth muscle cells from bovine trachea.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Benzofurans; Calcium; Calcium Channel Blockers; Carbachol; Cattle; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Cytosol; Fura-2; Isoproterenol; Muscle, Smooth; Pertussis Toxin; Tetradecanoylphorbol Acetate; Trachea; Virulence Factors, Bordetella | 1988 |
Regulation of phosphorylase A formation and calcium content in aortic smooth muscle and smooth muscle cells: effects of atrial natriuretic peptide II.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Benzofurans; Calcium; Cells, Cultured; Colforsin; Cyclic GMP; Fura-2; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Norepinephrine; Phosphorylase a; Phosphorylases; Potassium Chloride; Rats; Rats, Inbred Strains | 1988 |
The effects of follicle-stimulating hormone and cyclic guanosine 3',5'-monophosphate on cyclic adenosine 3',5'-monophosphate-phosphodiesterase and resumption of meiosis in hamster cumulus-oocyte complexes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminoquinolines; Animals; Atrial Natriuretic Factor; Colforsin; Cricetinae; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Follicle Stimulating Hormone; Meiosis; Nitroprusside; Oocytes; Proestrus; SRS-A; Time Factors | 1988 |
Beta-adrenergic stimulation of ion transport in primary cultures of avian salt glands.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Atropine; Biological Transport, Active; Carbachol; Cells, Cultured; Colforsin; Cyclic GMP; Ducks; Epinephrine; Furosemide; Ions; Kinetics; Ouabain; Phentolamine; Propranolol; Salt Gland | 1987 |
Atrial natriuretic peptide (ANP), guanylate cyclase, and intraocular pressure in the rabbit eye.
Topics: Adenylyl Cyclases; Animals; Atrial Natriuretic Factor; Ciliary Body; Colforsin; Cyclic GMP; Egtazic Acid; Guanylate Cyclase; Injections; Intraocular Pressure; Phosphoric Diester Hydrolases; Rabbits; Vitreous Body | 1987 |
The effect of Escherichia coli STa enterotoxin and other secretagogues on mucosal surface pH of rat small intestine in vivo.
Topics: Animals; Bacterial Toxins; Cholera Toxin; Colforsin; Cyclic GMP; Enterotoxins; Escherichia coli Proteins; Hydrogen-Ion Concentration; Ileum; Intestinal Mucosa; Jejunum; Kinetics; Male; Microelectrodes; Perfusion; Rats; Rats, Inbred Strains; Reference Values; Theophylline | 1988 |
Cyclic nucleotides and contractility of isolated soleus muscle.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscles; Terbutaline | 1985 |
Stimulation of cyclic GMP formation in smooth muscle cells by atriopeptin II.
Topics: Animals; Atrial Natriuretic Factor; Carbachol; Cell Line; Colforsin; Cyclic GMP; Diterpenes; Female; Humans; Kidney; Lung; Muscle Proteins; Muscle, Smooth, Vascular; Nitroprusside; Pregnancy; Rabbits | 1985 |
Atrial natriuretic factor increases cyclic GMP and inhibits cyclic AMP in rat renal papillary collecting tubule cells in culture.
Topics: Adenylyl Cyclase Inhibitors; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Diuresis; Kidney Tubules; Kinetics; Male; Muscle Proteins; Rats; Rats, Inbred Strains | 1985 |
Effects of atrial natriuretic factor, sodium nitroprusside, and acetylcholine on cyclic GMP levels and relaxation in rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Colforsin; Cyanides; Cyclic GMP; Ferricyanides; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Potassium Chloride; Rats; Sodium-Potassium-Exchanging ATPase | 1985 |
Lymphocyte protein kinase activity in cells from young and elderly men and women.
Topics: Adult; Aged; Aging; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Female; Humans; Isoproterenol; Lymphocytes; Male; Middle Aged; Propranolol; Protein Kinases; Sex Factors | 1985 |
Regulation of thyroxine 5'-deiodinase by thyroid hormones and activators of protein kinase C in GH4C1 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Cell Line; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Hypothyroidism; Iodide Peroxidase; Phorbol Esters; Pituitary Neoplasms; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Thyroid Hormones; Thyrotropin-Releasing Hormone; Thyroxine; Trifluoperazine; Triiodothyronine; Triiodothyronine, Reverse | 1986 |
Inhibition of vasopressin action by atrial natriuretic factor.
Topics: Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Cyclic GMP; Diuresis; In Vitro Techniques; Kidney Tubules; Kidney Tubules, Collecting; Rabbits | 1986 |
Effects of forskolin and cyclic nucleotides on isometric force in rat aorta.
Topics: Animals; Aorta, Thoracic; Bucladesine; Colforsin; Cyclic GMP; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Vasomotor System | 1986 |
[Cyclic nucleotides].
Topics: Animals; Bronchi; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Nitro Compounds | 1985 |
Effects of the cyclic GMP lowering agent LY83583 on the interaction of carbachol with forskolin in rabbit isolated cardiac preparations.
Topics: Aminoquinolines; Animals; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Drug Interactions; Ethanol; Heart; Heart Atria; Myocardium; Papillary Muscles; Rabbits | 1986 |
Effect of age on the formation of cyclic nucleotides in guinea-pig tracheal smooth muscle in response to pharmacological agents.
Topics: Aging; Alprostadil; Animals; Carbachol; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Nitroprusside; Potassium; Trachea | 1986 |
Effects of forskolin on pancreatic exocrine secretion and cyclic nucleotide concentrations of the dog pancreas.
Topics: Animals; Atropine; Cimetidine; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Female; Male; Nucleotides, Cyclic; Pancreatic Juice; Phentolamine; Propranolol; Sulpiride; Verapamil | 1987 |
A comparison of the effects of forskolin and nitroprusside on cyclic nucleotides and relaxation in the rat aorta.
Topics: Animals; Aorta, Thoracic; Bucladesine; Calcium; Colforsin; Cyclic GMP; Diterpenes; Ferricyanides; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Nucleotides, Cyclic; Potassium Chloride; Protein Kinases; Rats; Rats, Inbred Strains | 1984 |
The interaction of carbachol and forskolin in rabbit papillary muscles.
Topics: Animals; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Drug Interactions; Electric Stimulation; Muscle, Smooth, Vascular; Myocardial Contraction; Papillary Muscles; Rabbits | 1984 |
A modulatory octopaminergic neurone increases cyclic nucleotide levels in locust skeletal muscle.
Topics: 1-Methyl-3-isobutylxanthine; Amines; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Electric Stimulation; Female; Grasshoppers; Male; Muscles; Neuromuscular Junction; Octopamine; Stereoisomerism; Stimulation, Chemical | 1984 |
Cyclic nucleotide-dependent enzyme secretion in the rat lacrimal gland.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Carbachol; Cardiotonic Agents; Colforsin; Cyclic GMP; Diterpenes; In Vitro Techniques; Isoenzymes; Lacrimal Apparatus; Male; Peroxidase; Peroxidases; Rats; Rats, Inbred Strains; Stimulation, Chemical; Time Factors | 1984 |
3',5'-cyclic adenosine monophosphate and adenylate cyclase in phototransduction by limulus ventral photoreceptors.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Fluorides; Horseshoe Crabs; In Vitro Techniques; Light; Photoreceptor Cells; Time Factors; Vanadates; Vanadium | 1984 |
Forskolin perturbs cGMP as well as cAMP levels in human thyroid cells.
Topics: 1-Methyl-3-isobutylxanthine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Humans; Phosphodiesterase Inhibitors; Thyroid Gland; Thyrotropin | 1984 |
Bicarbonate transport across the frog choroid plexus and its control by cyclic nucleotides.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bicarbonates; Biological Transport, Active; Cholera Toxin; Choroid Plexus; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Hormones; Hydrogen-Ion Concentration; In Vitro Techniques; Membrane Potentials; Nucleotides, Cyclic; Rana catesbeiana; Theophylline | 1983 |
Forskolin, cyclic nucleotides and positive inotropism in isolated papillary muscles of the rabbit.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nitroprusside; Papillary Muscles; Rabbits | 1984 |
Histamine H3-receptor-induced inhibition of duodenal cholinergic transmission is independent of intracellular cyclic AMP and GMP.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Clonidine; Colforsin; Cyclic AMP; Cyclic GMP; Duodenum; Guinea Pigs; Histamine Agonists; In Vitro Techniques; Male; Methylhistamines; Parasympathetic Nervous System; Receptors, Histamine H3; Signal Transduction; Synaptic Transmission | 1993 |
Relaxant mechanisms of cyclic AMP-increasing agents in porcine coronary artery.
Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Ethanolamines; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Ryanodine; Swine; Thromboxane A2; Vasodilator Agents | 1994 |
Forskolin and 3-isobutyl-1-methylxanthine increase basal and sodium nitroprusside-elevated cyclic GMP levels in adult guinea-pig cerebellar slices.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cerebellum; Colforsin; Cyclic AMP; Cyclic GMP; Ferrocyanides; Guinea Pigs; In Vitro Techniques; Nitric Oxide; Nitroprusside | 1994 |
Cross talk among cyclic AMP, cyclic GMP, and Ca(2+)-dependent intracellular signalling mechanisms in brain capillary endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Capillaries; Cells, Cultured; Cerebrovascular Circulation; Colforsin; Cyclic AMP; Cyclic GMP; Endothelins; Endothelium, Vascular; Enzyme Activation; Guanylate Cyclase; Intracellular Membranes; Isoproterenol; Rats; Receptors, Endothelin; Signal Transduction | 1994 |
S35b, a new phenylsulfonylfuroxan compound, inhibits thrombin-induced synthesis of platelet-activating factor and prostacyclin in human endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Acetyltransferases; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Humans; Iloprost; Oxadiazoles; Platelet Activating Factor; Platelet Aggregation Inhibitors; Thrombin; Umbilical Veins | 1993 |
Involvement of cAMP and cGMP in the mode of action of molt-inhibiting hormone (MIH) a neuropeptide which inhibits steroidogenesis in a crab.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Brachyura; Bucladesine; Colforsin; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Ecdysone; Invertebrate Hormones | 1994 |
Influence of atrial natriuretic peptide on cyclic nucleotides and amylase release in rat parotid salivary gland in vitro.
Topics: Amylases; Animals; Atrial Natriuretic Factor; Bucladesine; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Isoproterenol; Male; Nitroprusside; Parotid Gland; Rats; Rats, Wistar; Stimulation, Chemical | 1994 |
Potentiation by forskolin of both SNP- and ANP-stimulated cyclic GMP accumulation in porcine isolated palmar lateral vein.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Colforsin; Cyclic GMP; Drug Synergism; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitroprusside; Pyrrolidinones; Rolipram; Veins | 1994 |
Endothelin secretion is regulated by cyclic AMP and phosphatase 2A in endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Endothelins; Endothelium, Vascular; Ethers, Cyclic; Humans; In Vitro Techniques; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 2 | 1994 |
Phorbol ester activation of protein kinase C inhibits CNP-stimulated cyclic GMP production in the mouse AtT-20 pituitary tumour cell line.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Cell Line; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Kinetics; Mice; Natriuretic Peptide, C-Type; Pituitary Neoplasms; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1994 |
YC-1, a novel activator of platelet guanylate cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Alprostadil; Animals; Bleeding Time; Blood Platelets; Calcium; Colforsin; Collagen; Cyclic AMP; Cyclic GMP; Drug Interactions; Enzyme Activation; Guanylate Cyclase; Imidazoles; Indazoles; Indomethacin; Methemoglobin; Mice; Molecular Structure; Nitroprusside; Phosphoric Diester Hydrolases; Platelet Aggregation Inhibitors; Prostaglandin D2; Rabbits; Superoxide Dismutase; Thromboxane A2 | 1994 |
Impaired cyclic nucleotide-dependent vasorelaxation in human umbilical artery smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carotid Arteries; Cattle; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Humans; In Vitro Techniques; Isometric Contraction; Kinetics; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Phosphorylation; Serotonin; Umbilical Arteries | 1995 |
Voltage-activated K channel in luminal membrane of marginal cells of stria vascularis dissected from guinea pig.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Cytoplasm; Electric Stimulation; Electrophysiology; Gluconates; Guinea Pigs; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Sodium Chloride; Stria Vascularis | 1994 |
Influence of nitric oxide synthase inhibition, nitric oxide and hydroperoxide on insulin release induced by various secretagogues.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Colforsin; Cyclic AMP; Cyclic GMP; Female; Glucose; Hydrogen Peroxide; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Insulin; Islets of Langerhans; Mice; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxides; Reactive Oxygen Species; tert-Butylhydroperoxide; Vasodilator Agents | 1995 |
Role of nitric oxide and cAMP in beta-adrenoceptor-induced pial artery vasodilation.
Topics: Albuterol; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Colforsin; Cyclic AMP; Cyclic GMP; Dobutamine; Enzyme Activation; Female; Isoproterenol; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Pia Mater; Receptors, Adrenergic, beta; Swine; Vasodilation | 1995 |
Change in vascular cAMP and cGMP contents in portal hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arteries; Colforsin; Cyclic AMP; Cyclic GMP; Hemodynamics; Hypertension, Portal; Rats; Rats, Sprague-Dawley | 1995 |
Influence of age on the signal transduction pathway of non-adrenergic non-cholinergic neurotransmitters in the rat gastric fundus.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Analysis of Variance; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Electric Stimulation; Gastric Fundus; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Rats; Rats, Wistar; Signal Transduction; Vasoactive Intestinal Peptide | 1995 |
Autonomic regulation of cardiac chloride current.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Autonomic Agents; Chloride Channels; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Isoproterenol | 1994 |
IBMX induces calcium release from intracellular stores in rat sensory neurones.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Biological Transport; Bucladesine; Caffeine; Calcium; Cell Compartmentation; Colforsin; Cyclic GMP; Dibutyryl Cyclic GMP; Endoplasmic Reticulum; Ganglia, Spinal; Neurons, Afferent; Rats; Theophylline | 1995 |
Effect of cAMP and cGMP on endothelin-stimulated tyrosine phosphorylation in rabbit platelets.
Topics: Animals; Blood Platelets; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelins; Molecular Weight; Phosphorylation; Phosphotyrosine; Rabbits; Signal Transduction | 1995 |
L-NMMA blocks carbachol-induced increases in cGMP levels but not decreases in tension in the presence of forskolin in rabbit papillary muscles.
Topics: Animals; Arginine; Carbachol; Colforsin; Cyclic GMP; Female; Guanylate Cyclase; In Vitro Techniques; Male; Muscarinic Agonists; Myocardial Contraction; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Papillary Muscles; Rabbits | 1995 |
Inhibitory effects of superoxide dismutase and cyclic guanosine 3',5'-monophosphate on estrogen production in cultured rat granulosa cells.
Topics: Animals; Bucladesine; Catalase; Cells, Cultured; Colforsin; Cyclic GMP; Estrogens; Female; Follicle Stimulating Hormone; Granulosa Cells; Nitric Oxide; Progesterone; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 1995 |
Opposite regulation of renin gene expression by cyclic AMP and calcium in isolated mouse juxtaglomerular cells.
Topics: Animals; Autoradiography; Base Sequence; Calcium; Calcium Chloride; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Egtazic Acid; Gene Expression Regulation; Juxtaglomerular Apparatus; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Nitric Oxide; Polymerase Chain Reaction; Renin; RNA, Messenger; Tetradecanoylphorbol Acetate | 1995 |
Effects of subarachnoid hemorrhage on vascular responses to calcitonin gene-related peptide and its related second messengers.
Topics: Analysis of Variance; Animals; Basilar Artery; Calcitonin Gene-Related Peptide; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Ischemic Attack, Transient; Isometric Contraction; Male; Nitroglycerin; Potassium; Rabbits; Serotonin; Subarachnoid Hemorrhage; Vasodilation | 1995 |
Regulations by cyclic nucleotides and phorbol ester of calcium efflux from cultured bovine adrenal chromaffin cells.
Topics: Animals; Calcium; Cattle; Cells, Cultured; Chromaffin System; Colforsin; Cyclic AMP; Cyclic GMP; Nitroprusside; Nucleotides, Cyclic; Phorbol Esters; Time Factors | 1995 |
Interleukin-1 beta effects on cyclic GMP and cyclic AMP in cultured rat islets of Langerhans-arginine-dependence and relationship to insulin secretion.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Antihypertensive Agents; Arginine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Kinetics; Molsidomine; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley | 1993 |
Initial biochemical and functional characterization of cyclic nucleotide phosphodiesterase isozymes in canine colonic smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Colforsin; Colon; Cyclic AMP; Cyclic GMP; Dogs; Isoenzymes; Muscle, Smooth; Phosphodiesterase Inhibitors; Purinones; Pyrrolidinones; Rolipram | 1993 |
HS-142-1 inhibits testosterone production and guanosine-3':5'-cyclic monophosphate accumulation stimulated by atrial natriuretic peptide in isolated mouse Leydig cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Chorionic Gonadotropin; Colforsin; Cyclic GMP; Gene Expression Regulation; Leydig Cells; Male; Mice; Polysaccharides; Rats; Receptors, Atrial Natriuretic Factor; Second Messenger Systems; Testosterone | 1993 |
cAMP regulates soluble guanylate cyclase beta 1-subunit gene expression in RFL-6 rat fetal lung fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cell Line; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation, Enzymologic; Guanylate Cyclase; Kinetics; Lung; Macromolecular Substances; Nitroprusside; Rats; RNA, Messenger | 1993 |
Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of beta-amyloid precursor.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Glutamic Acid; Hippocampus; Neurons; Rats | 1995 |
Protamine does not affect the formation of cGMP or cAMP in pig vascular smooth muscle cells in response to vasodilators.
Topics: Analysis of Variance; Animals; Atrial Natriuretic Factor; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Isoproterenol; Muscle, Smooth, Vascular; Nitroprusside; Prospective Studies; Protamines; Swine; Vasodilator Agents | 1995 |
cAMP-associated inhibition of phenobarbital-inducible cytochrome P450 gene expression in primary rat hepatocyte cultures.
Topics: Albumins; Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Benzoflavones; beta-Naphthoflavone; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dichlororibofuranosylbenzimidazole; Dose-Response Relationship, Drug; Enzyme Induction; Gene Expression Regulation, Enzymologic; Glucagon; Liver; Mixed Function Oxygenases; Molecular Sequence Data; Phenobarbital; Phosphodiesterase Inhibitors; Rats; Stereoisomerism; Steroid Hydroxylases; Thionucleotides; Transcriptional Activation | 1995 |
Calcitonin gene-related peptide selectively increases cAMP levels in the guinea-pig ureter.
Topics: Animals; Benzopyrans; Calcitonin Gene-Related Peptide; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Drug Interactions; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Potassium Channels; Pyrroles; Ureter | 1995 |
C-natriuretic peptide but not atrial natriuretic peptide increases cyclic GMP in cerebral arterial smooth muscle cells.
Topics: Animals; Atrial Natriuretic Factor; Cells, Cultured; Cerebral Arteries; Colforsin; Coronary Vessels; Cyclic GMP; Female; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Natriuretic Peptide, C-Type; Proteins; Swine | 1995 |
Ca(2+)- and nitric oxide-dependent stimulation of cyclic GMP synthesis in neuronal cell line induced by P2-purinergic/pyrimidinergic receptor.
Topics: Adenosine Triphosphate; Aminoquinolines; Animals; Bradykinin; Calcium; Colforsin; Cyclic GMP; Glioma; Hybrid Cells; Ionomycin; Mice; Neuroblastoma; Neurons; Nitric Oxide; Radioimmunoassay; Rats; Receptors, Purinergic P2; Signal Transduction; Suramin; Tritium; Tumor Cells, Cultured | 1995 |
Stimulation of cyclic GMP accumulation by sodium nitroprusside is potentiated via a Gs mechanism in intact pinealocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic GMP; GTP-Binding Proteins; Nitroprusside; Pineal Gland; Rats; Receptors, Adrenergic | 1995 |
Effects of moxonidine, an imidazoline antihypertensive agent, on second messenger systems in rat brain.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Antihypertensive Agents; Brain Chemistry; Brain Stem; Brimonidine Tartrate; Cerebral Cortex; Colforsin; Cyclic AMP; Cyclic GMP; Imidazoles; In Vitro Techniques; Norepinephrine; Phosphatidylinositols; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Second Messenger Systems; Yohimbine | 1994 |
Effects of forskolin and organic nitrate on aggregation and intracellular cyclic nucleotide content in human platelets.
Topics: Adult; Blood Platelets; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Humans; Male; Nitroglycerin; Platelet Aggregation; Platelet Aggregation Inhibitors | 1994 |
Mechanisms of cyclic nucleotide-induced relaxation in canine tracheal smooth muscle.
Topics: Adenylyl Cyclases; Animals; Calcium Channels; Calcium-Transporting ATPases; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Female; Indoles; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Potassium Chloride; Sarcoplasmic Reticulum; Trachea | 1995 |
Nitric oxide regulates cardiac Ca2+ current. Involvement of cGMP-inhibited and cGMP-stimulated phosphodiesterases through guanylyl cyclase activation.
Topics: Animals; Calcium Channels; Colforsin; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Heart Ventricles; In Vitro Techniques; Isoproterenol; Molsidomine; Nitric Oxide; Phosphoric Diester Hydrolases; Rana esculenta | 1993 |
Endothelin ETB receptors couple to two distinct signaling pathways in porcine kidney epithelial LLC-PK1 cells.
Topics: Amino Acid Sequence; Animals; Arginine Vasopressin; Colforsin; Cyclic AMP; Cyclic GMP; Endothelin Receptor Antagonists; Endothelins; Epithelium; Glycopeptides; Kidney Tubules; LLC-PK1 Cells; Molecular Sequence Data; Oligopeptides; Peptides, Cyclic; Piperidines; Protein Binding; Receptor, Endothelin B; Receptors, Endothelin; Signal Transduction; Swine | 1994 |
Natriuretic peptide clearance receptor is transcriptionally down-regulated by beta 2-adrenergic stimulation in vascular smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Antagonists; Amino Acid Sequence; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Blotting, Northern; Blotting, Western; Cell Membrane; Cells, Cultured; Colforsin; Cyclic GMP; Down-Regulation; Gene Expression; Guanylate Cyclase; Isoproterenol; Kinetics; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Norepinephrine; Propanolamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Sodium Fluoride | 1994 |
Smooth muscle tone regulation in rabbit cavernosal and spongiosal tissue by cyclic AMP- and cyclic GMP-dependent mechanisms.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Molsidomine; Muscle Tonus; Muscle, Smooth; Penis; Phenylephrine; Phosphodiesterase Inhibitors; Rabbits | 1994 |
Regulation of calcium channel current in A7r5 vascular smooth muscle cells by cyclic nucleotides.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Channels; Cell Line; Colforsin; Cyclic GMP; Dimethyl Sulfoxide; Diterpenes; Electrophysiology; Muscle, Smooth, Vascular; Rats | 1994 |
Differential regulation of natriuretic peptide receptor activity in vascular cells.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Cattle; Cells, Cultured; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Muscle, Smooth, Vascular; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Tetradecanoylphorbol Acetate | 1994 |
Developmental appearance of pineal adrenergic-->guanosine 3',5'-monophosphate response is determined by a process down-stream from elevation of intracellular Ca2+: possible involvement of a diffusible factor.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adrenal Glands; Aging; Animals; Arachidonic Acid; Calcium; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Cytosol; Guanylate Cyclase; Isoproterenol; Kinetics; Mice; Norepinephrine; Organ Culture Techniques; Phospholipases A; Phospholipases A2; Pineal Gland; Potassium; Protein Kinases; Rats; Tetradecanoylphorbol Acetate | 1993 |
The role of cyclic nucleotides in the release of tissue-type plasminogen activator and von Willebrand factor.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Atrial Natriuretic Factor; Bradykinin; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Male; Nitroprusside; Platelet Activating Factor; Rats; Rats, Wistar; Secretory Rate; Tissue Plasminogen Activator; von Willebrand Factor | 1993 |
Effect of flosequinan on ischaemia-induced arrhythmias and on ventricular cyclic nucleotide content in the anaesthetized rat.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Enzyme Activation; Isoproterenol; Male; Milrinone; Myocardial Ischemia; Myocardium; Phosphodiesterase Inhibitors; Pyridones; Quinolines; Rats; Rats, Wistar; Vasodilator Agents | 1993 |
Regulation of cAMP-activated apical membrane chloride conductance in gallbladder epithelium.
Topics: Animals; Calcium; Chloride Channels; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Electrophysiology; Enzyme Activation; Epithelium; Ethers, Cyclic; Gallbladder; In Vitro Techniques; Ionomycin; Membrane Potentials; Necturus; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Theophylline | 1994 |
Regulation of Ca2+ channels by cAMP and cGMP in vascular smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Channels; Colforsin; Cyclic AMP; Cyclic GMP; Electrophysiology; Isoproterenol; Muscle, Smooth, Vascular; Nucleotides, Cyclic; Osmolar Concentration; Rabbits | 1993 |
Distribution and regulation of natriuretic factor-R1C receptor subtypes in mammalian cell lines.
Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Atrial Natriuretic Factor; Cattle; Cell Line; Colforsin; Cyclic GMP; Humans; Mice; Natriuretic Peptide, C-Type; Nerve Tissue Proteins; Rats; Receptors, Atrial Natriuretic Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Isoproterenol- and insulin-induced hyperpolarization in rat skeletal muscle.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Insulin; Isoproterenol; Male; Membrane Potentials; Muscles; Ouabain; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1993 |
Pigment granule migration and phototransduction are triggered by separate pathways in fly photoreceptor cells.
Topics: Animals; Azides; Bucladesine; Colforsin; Color; Cyclic GMP; Cytoplasmic Granules; Egtazic Acid; Female; Houseflies; Nitroprusside; Photic Stimulation; Photoreceptor Cells; Retinal Pigments; Sodium Azide; Time Factors | 1993 |
Extracellular calcium exerts a dual effect on renin secretion from isolated mouse juxtaglomerular cells.
Topics: Animals; Calcium; Cells, Cultured; Cobalt; Colforsin; Cyclic GMP; Egtazic Acid; Juxtaglomerular Apparatus; Male; Mice; Mice, Inbred C57BL; Renin; Sucrose; Thionucleotides | 1993 |
Congestive heart failure alters receptor-dependent cAMP-mediated relaxation of canine pulmonary arteries.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Heart; Heart Failure; Myocardial Contraction; Phosphodiesterase Inhibitors; Pulmonary Artery; Receptors, Cell Surface; Vasodilation | 1993 |
The relaxant actions on guinea-pig trachealis of atherosperminine isolated from Fissistigma glaucescens.
Topics: Alkaloids; Animals; Benzopyrans; Calcium; Calmodulin; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Egtazic Acid; Epithelium; Female; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nifedipine; Nitroprusside; Phenanthrenes; Plants, Medicinal; Propranolol; Pyrroles; Theophylline; Trachea; Vasodilator Agents | 1993 |
Differential modulation of voltage-activated conductances by intracellular and extracellular cyclic nucleotides in leech salivary glands.
Topics: Action Potentials; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Ion Channels; Leeches; Patch-Clamp Techniques; Salivary Glands; Time Factors | 1995 |
Urokinase-type plasminogen activator-induced monocyte adhesion requires a carboxyl-terminal lysine and cAMP-dependent signal transduction.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Binding Sites; Cell Adhesion; Cell Line; Colforsin; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Humans; Isoflurophate; Kinetics; Monocytes; Peptide Fragments; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Urokinase-Type Plasminogen Activator | 1995 |
Intracellular dialysis of cyclic nucleotides induces inward currents in turtle vomeronasal receptor neurons.
Topics: Action Potentials; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Microdialysis; Nasal Septum; Olfactory Receptor Neurons; Patch-Clamp Techniques; Turtles | 1996 |
cGMP modulates transport across the ciliary epithelium.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Barium; Bumetanide; Cats; Cells, Cultured; Chloride Channels; Chlorides; Ciliary Body; Colforsin; Cyclic AMP; Cyclic GMP; Epithelium; Humans; Male; Models, Biological; Patch-Clamp Techniques; Potassium Channels; Rabbits; Second Messenger Systems; Sodium-Potassium-Exchanging ATPase; Species Specificity; Strophanthidin | 1995 |
Effects of phosphodiesterase inhibitors and forskolin on cyclic GMP-activated channels in intact isolated cells of the chick pineal gland.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Chick Embryo; Chickens; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Ion Channel Gating; Ion Channels; Papaverine; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Pineal Gland | 1995 |
Berberine inhibition of electrogenic ion transport in rat colon.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bacterial Toxins; Berberine; Biological Transport; Chlorides; Colforsin; Colon; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cytochalasin D; Enterotoxins; Epithelium; Escherichia coli Proteins; In Vitro Techniques; Ions; Male; Membrane Potentials; Rats; Rats, Wistar; Secretory Rate; Sensitivity and Specificity; Signal Transduction; Terpenes; Thapsigargin | 1995 |
Involvement of cyclic AMP at the level of the nucleus reticularis pontis caudalis in the acoustic startle response.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acoustic Stimulation; Adenosine Triphosphate; Analysis of Variance; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Male; Rats; Rats, Sprague-Dawley; Reflex, Startle; Reticular Formation | 1995 |
Protein kinase C modulates natriuretic peptide receptors in astroglial cultures from rat brain.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Animals, Newborn; Astrocytes; Atrial Natriuretic Factor; Binding Sites; Brain Stem; Cells, Cultured; Colforsin; Cyclic GMP; Down-Regulation; Enzyme Inhibitors; Hypothalamus; Kinetics; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor; Staurosporine; Tetradecanoylphorbol Acetate; Up-Regulation | 1996 |
Specific potentiation by cyclic AMP of natriuretic peptide-mediated cyclic GMP production in adipose tissue.
Topics: 3T3 Cells; Adipose Tissue; Adrenergic beta-Agonists; Animals; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Cyclic GMP; Isoproterenol; Mice; Natriuretic Peptide, C-Type; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor | 1996 |
Effects of various phosphodiesterase-inhibitors, forskolin, and sodium nitroprusside on porcine detrusor smooth muscle tonic responses to muscarinergic stimulation and cyclic nucleotide levels in vitro.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guanylate Cyclase; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Receptors, Muscarinic; Signal Transduction; Swine; Urinary Bladder; Vasodilator Agents | 1996 |
Phosphorylation of the inositol 1,4,5-trisphosphate receptor. Cyclic GMP-dependent protein kinase mediates cAMP and cGMP dependent phosphorylation in the intact rat aorta.
Topics: Alkaloids; Angiotensin II; Animals; Aorta; Calcium Channels; Carbazoles; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Male; Nitroprusside; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Thionucleotides; Time Factors | 1996 |
Thyroid hormone activation of transcription is potentiated by activators of cAMP-dependent protein kinase.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Binding Sites; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; DNA-Binding Proteins; Enzyme Activation; Guanylate Kinases; Humans; Nucleoside-Phosphate Kinase; Phosphorylation; Protein Kinase C; Receptors, Thyroid Hormone; Transcription, Genetic; Triiodothyronine | 1996 |
Modulation of the hyperpolarization-activated current (Ih) by cyclic nucleotides in guinea-pig primary afferent neurons.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adenosine; Adenosine Monophosphate; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dibutyryl Cyclic GMP; Dinoprostone; Guinea Pigs; In Vitro Techniques; Ion Channels; Neurons, Afferent; Nodose Ganglion; Nucleotides, Cyclic; Patch-Clamp Techniques; Phosphorylation; Second Messenger Systems; Thionucleotides; Trigeminal Ganglion | 1996 |
Simultaneous presence of cAMP and cGMP exert a co-ordinated inhibitory effect on the agonist-evoked Ca2+ signal in pancreatic acinar cells.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Drug Synergism; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Mice; Pancreas; Papaverine; Phosphoric Diester Hydrolases; Signal Transduction; Theophylline | 1996 |
Cardiovascular effects of a novel, potent and selective phosphodiesterase 5 inhibitor, DMPPO: in vitro and in vivo characterization.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adrenergic alpha-Agonists; Allopurinol; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Blood Pressure; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Hemodynamics; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Vasodilator Agents | 1996 |
Inter-relationships between nonapeptide hormones and cyclic nucleotides within cultured porcine granulosa cells.
Topics: Animals; Arginine Vasopressin; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Feedback; Female; Granulosa Cells; Luteinizing Hormone; Nucleotides, Cyclic; Oxytocin; Pituitary Hormones, Posterior; Stimulation, Chemical; Swine | 1996 |
Effects of cyclic GMP elevation on isoprenaline-induced increase in cyclic AMP and relaxation in rat aortic smooth muscle: role of phosphodiesterase 3.
Topics: Adrenergic beta-Agonists; Allopurinol; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Phosphodiesterase Inhibitors; Rats; Vasodilator Agents | 1996 |
Force and intracellular Ca2+ during cyclic nucleotide-mediated relaxation of rat anococcygeus muscle and the effects of cyclopiazonic acid.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Indoles; Male; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Rats; Rats, Sprague-Dawley | 1996 |
Cyclic GMP-dependent protein kinase is required for thrombospondin and tenascin mediated focal adhesion disassembly.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Cattle; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Colforsin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelium, Vascular; Enzyme Inhibitors; Membrane Glycoproteins; Muscle, Smooth, Vascular; Osteonectin; Penicillamine; Protein Serine-Threonine Kinases; Rats; S-Nitroso-N-Acetylpenicillamine; Tenascin; Thrombospondins; Transfection | 1996 |
Effect of molsidomine on basal Ca2+ current in rat cardiac cells.
Topics: Animals; Calcium; Colforsin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Heart; Heart Ventricles; In Vitro Techniques; Milrinone; Molsidomine; Myocardium; Nitric Oxide; Patch-Clamp Techniques; Pyridones; Rats; Vasodilator Agents | 1997 |
The influence of surgical preparation on cyclic nucleotide synthesis in an organ culture of human saphenous vein.
Topics: Acetylcholine; Adult; Aged; Alprostadil; Calcimycin; Colforsin; Coronary Artery Bypass; Cyclic AMP; Cyclic GMP; DNA; Humans; Middle Aged; Organ Culture Techniques; Radioimmunoassay; Saphenous Vein; Tunica Intima | 1997 |
Morphological plasticity of cultured astrocytes derived from the subfornical organ of the adult rat.
Topics: Animals; Astrocytes; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Immunohistochemistry; Male; Neuronal Plasticity; Nitroprusside; Rats; Rats, Sprague-Dawley; Subfornical Organ | 1997 |
Glucose stimulates islet beta-cell mitogenesis through GTP-binding proteins and by protein kinase C-dependent mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Atrial Natriuretic Factor; Calcium Channel Blockers; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gallopamil; Glucose; GTP-Binding Proteins; Insulin; Insulin Secretion; Ionomycin; Ionophores; Islets of Langerhans; Pertussis Toxin; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1997 |
Inhibition of [Ca2+]i transients in rat adrenal chromaffin cells by neuropeptide Y: role for a cGMP-dependent protein kinase-activated K+ conductance.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Glands; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cholinergic Agonists; Chromaffin Cells; Colforsin; Cyclic AMP; Cyclic GMP; Electrophysiology; In Vitro Techniques; Ion Channel Gating; Male; Neuropeptide Y; Potassium; Potassium Channels; Rats; Rats, Wistar | 1997 |
Effect of contrast medium on corpus cavernosum smooth muscle.
Topics: Animals; Colforsin; Contrast Media; Cyclic AMP; Cyclic GMP; Diatrizoate; Dose-Response Relationship, Drug; In Vitro Techniques; Iohexol; Male; Muscle Contraction; Muscle, Smooth; Penis; Phosphodiesterase Inhibitors; Rabbits; Triiodobenzoic Acids | 1997 |
Atrial natriuretic peptide and cyclic nucleotides affect glucose-induced Ca2+ responses in single pancreatic islet beta-cells: correlation with (Ca[2+] + Mg2+)-ATPase activity.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gallopamil; Glucose; Islets of Langerhans; Male; Nucleotides, Cyclic; Rats; Rats, Sprague-Dawley; Thapsigargin | 1997 |
Effects of cAMP and cGMP on L-type calcium channel currents in rat mesenteric artery cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bucladesine; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoquinolines; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Patch-Clamp Techniques; Rats; Rats, Wistar | 1997 |
cAMP induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle.
Topics: Animals; Aorta; Blood Platelets; Bucladesine; Carbon Monoxide; Cells, Cultured; Coculture Techniques; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Induction; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Isoproterenol; Muscle, Smooth, Vascular; omega-N-Methylarginine; Polymerase Chain Reaction; Protoporphyrins; Rats; RNA, Messenger; Transcription, Genetic | 1997 |
Stimulation of eating by the second messenger cAMP in the perifornical and lateral hypothalamus.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Eating; Hypothalamic Area, Lateral; Male; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Stereotaxic Techniques; Thalamus | 1997 |
Involvement of protein kinase C in homologous desensitization of histamine-evoked secretory responses in rat chromaffin cells.
Topics: Animals; Calcium; Carcinogens; Catecholamines; Chromaffin Cells; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cytoplasmic Granules; Desensitization, Immunologic; Enzyme Inhibitors; GTP-Binding Proteins; Histamine; Indoles; Male; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Receptors, Histamine H1; Stimulation, Chemical | 1997 |
Gallbladder relaxation in patients with pigment and cholesterol stones.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cholelithiasis; Cholesterol; Colforsin; Cyclic AMP; Cyclic GMP; Electric Stimulation; Enzyme Activation; Gallbladder; Humans; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Pigments, Biological; Vasoactive Intestinal Peptide | 1997 |
Cyclic AMP-mediated regulation of vascular smooth muscle cell cyclic AMP phosphodiesterase activity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Aorta; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Muscle, Smooth, Vascular; Rats | 1997 |
Involvement of cyclic GMP in the mode of action of a new antithrombotic agent PCA-4230; inhibition of the platelet cyclic GMP dependent phosphodiesterase.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Colforsin; Cyclic AMP; Cyclic GMP; Dihydropyridines; Drug Synergism; Fibrinolytic Agents; Kinetics; Nitroprusside; Phosphodiesterase Inhibitors; Phosphorylation; Rabbits; Serotonin; Thrombin; Vasodilator Agents | 1997 |
Smooth muscle cell expression of type I cyclic GMP-dependent protein kinase is suppressed by continuous exposure to nitrovasodilators, theophylline, cyclic GMP, and cyclic AMP.
Topics: Animals; Aorta; Bucladesine; Cattle; Cell Nucleus; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Gene Expression Regulation, Enzymologic; Isosorbide; Kinetics; Male; Muscle, Smooth, Vascular; Nitroprusside; Penicillamine; Rats; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Theophylline; Thionucleotides; Transcription, Genetic; Vasodilator Agents | 1997 |
Inhibitory effect of 2-phenyl-4-quinolone on serotonin-mediated changes in the morphology and permeability of endothelial monolayers.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Cattle; Cell Size; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium; Enzyme Inhibitors; Gap Junctions; Myocardium; Nitroprusside; Permeability; Protein Kinase C; Quinolones; Rats; Serotonin; Serum Albumin; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
KATP channels contribute to beta- and adenosine receptor-mediated pulmonary vasorelaxation.
Topics: Acetylcholine; Adenosine; Adenylyl Cyclases; Animals; ATP-Binding Cassette Transporters; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Glyburide; In Vitro Techniques; Isoproterenol; KATP Channels; Kinetics; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Tolbutamide; Vasodilation | 1997 |
In vivo activation of CFTR-dependent chloride transport in murine airway epithelium by CNP.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chlorides; Colforsin; Cyclic GMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Mice; Mice, Knockout; Mice, Mutant Strains; Models, Biological; Nasal Mucosa; Natriuretic Peptide, C-Type; Nitroprusside; ortho-Aminobenzoates; Proteins; Trachea | 1997 |
Comparative effects of continuous warm blood and intermittent cold blood cardioplegia on coronary reactivity.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blood; Calcimycin; Colforsin; Coronary Vessels; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Guanidines; Heart Arrest, Induced; In Vitro Techniques; Isoproterenol; Microcirculation; Pinacidil; Potassium Channels; Swine; Temperature; Vasodilation; Vasodilator Agents | 1997 |
A functional CFTR protein is required for mouse intestinal cAMP-, cGMP- and Ca(2+)-dependent HCO3- secretion.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bacterial Toxins; Bicarbonates; Calcium; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprostone; Duodenum; Enterotoxins; Escherichia coli Proteins; Gastrointestinal Hormones; Ileum; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Jejunum; Kinetics; Mice; Mice, Knockout; Microvilli; Natriuretic Peptides; Peptides; Vasoactive Intestinal Peptide | 1997 |
cGMP facilitates calcium current via cGMP-dependent protein kinase in isolated rabbit ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Calcium Channels; Colforsin; Cyclic GMP; Electric Conductivity; Enzyme Inhibitors; Female; Heart; Isoproterenol; Male; Membrane Potentials; Protein Kinases; Rabbits; Thionucleotides | 1998 |
Cyclic AMP stimulates the cyclic GMP egression pump in human erythrocytes: effects of probenecid, verapamil, progesterone, theophylline, IBMX, forskolin, and cyclic AMP on cyclic GMP uptake and association to inside-out vesicles.
Topics: 1-Methyl-3-isobutylxanthine; Biological Transport, Active; Colforsin; Cyclic AMP; Cyclic GMP; Dimethyl Sulfoxide; Erythrocyte Membrane; Humans; Ion Pumps; Probenecid; Progesterone; Theophylline; Verapamil | 1998 |
Role of cyclic 3'5' guanosine monophosphate and nitric oxide in the regulation of iodide uptake in calf thyroid cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cattle; Cells, Cultured; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Iodine; Iodine Radioisotopes; Nitric Oxide; Nitroprusside; Thyroid Gland; Thyrotropin | 1997 |
The effect of chronic treatment with trandolapril on cyclic AMP-and cyclic GMP-dependent relaxations in aortic segments of rats with chronic heart failure.
Topics: Acetylcholine; Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Cardiac Output, Low; Colforsin; Cyclic AMP; Cyclic GMP; Hemodynamics; Indoles; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Wistar; Vasodilator Agents | 1998 |
Compartmentalization of PDE-4 and cAMP-dependent protein kinase in neutrophils and macrophages during phagocytosis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cell Adhesion; Cell Compartmentation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytochalasin D; Humans; Isoenzymes; Macrophages; Neutrophils; Nucleic Acid Synthesis Inhibitors; Peroxidase; Phagocytosis; Phagosomes; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram; Signal Transduction; Zymosan | 1998 |
The effect of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) and charybdotoxin (CTX) on relaxations of isolated cerebral arteries to nitric oxide.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bradykinin; Cerebral Arteries; Charybdotoxin; Colforsin; Cyclic GMP; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; In Vitro Techniques; Isometric Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitrogen Oxides; Oxadiazoles; Quinoxalines; Uridine Triphosphate | 1998 |
Modulation of Ca2+ channels by cyclic nucleotide cross activation of opposing protein kinases in rabbit portal vein.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Barium; Calcium; Calcium Channels; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Ion Channel Gating; Male; Membrane Potentials; Microdialysis; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Portal Vein; Rabbits; Time Factors | 1998 |
Indomethacin enhances endothelial NO release--evidence for a role of PGI2 in the autocrine control of calcium-dependent autacoid production.
Topics: Autocrine Communication; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Endothelium, Vascular; Epoprostenol; Feedback; Histamine; Humans; Indomethacin; Nitric Oxide; Umbilical Veins | 1997 |
Acceleration of myosin light chain dephosphorylation and relaxation of smooth muscle by telokin. Synergism with cyclic nucleotide-activated kinase.
Topics: Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; In Vitro Techniques; Kinetics; Muscle Proteins; Muscle Relaxation; Muscle, Smooth; Myosin-Light-Chain Kinase; Peptide Fragments; Peptides; Phosphorylation; Rabbits; Recombinant Proteins; Sulfhydryl Compounds | 1998 |
Mucin-like glycoprotein secretion is mediated by cyclic-AMP and protein kinase C signal transduction pathways in rat corneal epithelium.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbazoles; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelium, Corneal; Indoles; Male; Mucins; Naphthalenes; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction | 1998 |
Cyclic nucleotide-mediated regulation of vascular smooth muscle cell cyclic nucleotide phosphodiesterase activity. Selective effect of cyclic AMP.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Enzyme Activation; Exonucleases; Muscle, Smooth, Vascular; Nitroprusside; Phosphoric Diester Hydrolases; Rats | 1998 |
Identification of the spinal degradation products and inhibition of adenylate cyclase by recombinant rat galanin message-associated peptide.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; Colforsin; Cyclic AMP; Cyclic GMP; DNA Primers; Escherichia coli; Galanin; Gene Expression; Male; Molecular Sequence Data; Peptide Fragments; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Galanin; Receptors, Neuropeptide; Recombinant Proteins; Second Messenger Systems; Sequence Homology, Amino Acid; Spinal Cord | 1998 |
Effects of nitric oxide on adenylyl cyclase stimulation in N18TG2 neuroblastoma cells.
Topics: Adenylyl Cyclase Inhibitors; Animals; Calmodulin; Colforsin; Cyclic AMP; Cyclic GMP; GTP-Binding Protein alpha Subunits, Gi-Go; Mice; Molsidomine; Neuroblastoma; Nitric Oxide; Tumor Cells, Cultured | 1998 |
Effect of cAMP- and cGMP-related drugs on porcine cultured ciliary muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antihypertensive Agents; Bucladesine; Carbachol; Cells, Cultured; Ciliary Body; Colforsin; Cyclic AMP; Cyclic GMP; Immunoenzyme Techniques; Intraocular Pressure; Microscopy, Electron; Muscle Contraction; Muscle, Smooth; Nitroprusside; Phosphodiesterase Inhibitors; Swine | 1998 |
Regulation of extracellular calcium-activated cation currents by cAMP in parathyroid cells.
Topics: Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Kinetics; Membrane Potentials; Nifedipine; Parathyroid Glands; Patch-Clamp Techniques; Tetraethylammonium | 1998 |
Sildenafil inhibits phosphodiesterase type 5 in human clitoral corpus cavernosum smooth muscle.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Cells, Cultured; Clitoris; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Female; Humans; Hydrolysis; Kinetics; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Purinones; Sildenafil Citrate; Sulfones | 1998 |
Cl- transport in an immortalized human epithelial cell line (NCM460) derived from the normal transverse colon.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Bacterial Toxins; Biological Transport; Cell Line, Transformed; Chlorides; Colforsin; Colon; Cyclic AMP; Cyclic GMP; Cystic Fibrosis Transmembrane Conductance Regulator; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Fluorescent Dyes; Histamine; Humans; Intestinal Mucosa; Models, Biological; Phorbol 12,13-Dibutyrate; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic | 1998 |
ATP-sensitive K+ channels in smooth muscle cells of guinea-pig mesenteric lymphatics: role in nitric oxide and beta-adrenoceptor agonist-induced hyperpolarizations.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Colforsin; Cyclic GMP; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; Guinea Pigs; Isoproterenol; Isoquinolines; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitric Oxide; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Receptors, Adrenergic, beta; Sulfonamides | 1998 |
Role of cGMP-kinase II in the control of renin secretion and renin expression.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinase Type II; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Gene Expression Regulation; In Vitro Techniques; Juxtaglomerular Apparatus; Mice; Mice, Mutant Strains; Perfusion; Rats; Renin; Renin-Angiotensin System; RNA, Messenger | 1998 |
Cyclic AMP mediates endothelial protection by nitric oxide.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Alkaloids; Animals; Carbazoles; Cattle; Cell Line; Cell Survival; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic N-Oxides; Dideoxyadenosine; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Imidazoles; Indoles; Kinetics; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Pulmonary Artery; Pyrroles; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha | 1998 |
Relationship between decreased function and O2 consumption caused by cyclic GMP in cardiac myocytes and L-type calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analysis of Variance; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Colforsin; Cyclic GMP; Heart; Muscle Contraction; Myocardium; Nifedipine; Nitroprusside; Oxygen Consumption; Rabbits; Radioimmunoassay | 1998 |
Nitric oxide, prostacyclin and cyclic nucleotide formation in externally stented porcine vein grafts.
Topics: Animals; Autoradiography; Calcimycin; Carotid Arteries; Colforsin; Cyclic AMP; Cyclic GMP; Epoprostenol; Histocytochemistry; Ionophores; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; Radioimmunoassay; Saphenous Vein; Stents; Swine; Tunica Intima; Tunica Media | 1998 |
Light-induced pigment aggregation in xanthophores of the medaka, Oryzias latipes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Antagonists; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromatophores; Colforsin; Cyclic AMP; Cyclic GMP; Light; Melanosomes; Oryzias; Phentolamine; Phosphoric Diester Hydrolases; Skin Pigmentation; Sulfonamides | 1998 |
Expression of cyclic GMP-inhibited phosphodiesterases 3A and 3B (PDE3A and PDE3B) in rat tissues: differential subcellular localization and regulated expression by cyclic AMP.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Animals; Base Sequence; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Muscle, Smooth, Vascular; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1998 |
Endothelial defect mediates attenuated vasorelaxant response to isoproterenol after lung transplantation.
Topics: Adrenergic beta-Agonists; Animals; Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Endothelium, Vascular; Isoproterenol; Lung Transplantation; Oxypurinol; Pulmonary Artery; Transplantation, Autologous; Vasodilation | 1999 |
Regulation of natriuretic peptide (urodilatin) release in a human kidney cell line.
Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Calcimycin; Cell Line; Colforsin; Culture Media; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Humans; Intracellular Fluid; Kidney; Osmolar Concentration; Peptide Fragments; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1999 |
Growth-inhibitory effect of cyclic GMP- and cyclic AMP-dependent vasodilators on rat vascular smooth muscle cells: effect on cell cycle and cyclin expression.
Topics: Animals; Cell Count; Cell Cycle; Cell Division; Colforsin; Culture Media; Culture Media, Serum-Free; Cyclic AMP; Cyclic GMP; Cyclin A; Cyclin D1; Cyclin E; Cyclins; Gene Expression; Gene Expression Regulation; Male; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Wistar; RNA, Messenger; Vasodilator Agents | 1999 |
Relaxing effects of cyclic GMP and cyclic AMP-enhancing agents on the long-lasting contraction to endothelin-1 in the porcine coronary artery.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Caffeine; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelin-1; In Vitro Techniques; Isradipine; Milrinone; Muscle, Smooth, Vascular; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyrrolidinones; Rolipram; Swine; Vasoactive Intestinal Peptide; Vasoconstriction; Vasodilation; Verapamil; Vinca Alkaloids | 1998 |
Regulation of NO-elicited pulmonary artery relaxation and guanylate cyclase activation by NADH oxidase and SOD.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Catalase; Cattle; Colforsin; Cyclic GMP; Endothelium, Vascular; Estradiol; Guanylate Cyclase; Lactic Acid; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Nitric Oxide; Oxidation-Reduction; Penicillamine; Pulmonary Artery; Pyruvic Acid; Superoxide Dismutase; Superoxides; Vasodilation | 1999 |
Potentiation of cyclic AMP-mediated vasorelaxation by phenylephrine in pulmonary arteries of the rat.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprost; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Phenylephrine; Potassium Chloride; Pulmonary Artery; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 1999 |
Altered effects of acetylcholine on cyclic AMP and GMP induced changes in O2 consumption of hypertrophic dog cardiac myocytes.
Topics: Acetylcholine; Aminoquinolines; Animals; Cell Separation; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hypertrophy, Left Ventricular; In Vitro Techniques; Oxygen Consumption; Radioimmunoassay; Vasodilator Agents | 1999 |
Activation of cAMP signaling transiently inhibits apoptosis in vascular smooth muscle cells in a site upstream of caspase-3.
Topics: Animals; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspases; Cells, Cultured; Chromatin; Colforsin; Culture Media, Serum-Free; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cytoskeleton; Kinetics; Muscle, Smooth, Vascular; Rats; Signal Transduction | 1999 |
Nitric oxide inhibits human aldosteronogenesis without guanylyl cyclase stimulation.
Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Animals; Cell Line; Colforsin; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Humans; Hydroxycholesterols; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Nitroso Compounds; Oxadiazoles; PC12 Cells; Quinoxalines; Rats | 1999 |
Mechanism of SNAP potentiating antiproliferative effect of calcitonin gene-related peptide in cultured vascular smooth muscle cells.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Calcitonin Gene-Related Peptide; Cattle; Cell Division; Cells, Cultured; Colforsin; Culture Media; Cyclic AMP; Cyclic GMP; DNA; Drug Synergism; Humans; Muscle, Smooth, Vascular; Nitric Oxide Donors; Penicillamine; Rabbits; S-Nitroso-N-Acetylpenicillamine; Thymidine | 1999 |
Cyclic AMP is involved in cardioregulation by multiple neuropeptides encoded on the FMRFamide gene.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Amino Acid Sequence; Animals; Cell Membrane; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cyclic GMP; FMRFamide; Heart; Heart Rate; Isoleucine; Lymnaea; Molecular Sequence Data; Myocardial Contraction; Neuropeptides; Second Messenger Systems; Signal Transduction | 1999 |
Cyclic GMP and cyclic AMP induced changes in control and hypertrophic cardiac myocyte function interact through cyclic GMP affected cyclic-AMP phosphodiesterases.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cardiomegaly; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Heart; Milrinone; Oxadiazoles; Oxygen Consumption; Purinones; Quinoxalines | 1999 |
Development of human and rabbit vaginal smooth muscle cell cultures: effects of vasoactive agents on intracellular levels of cyclic nucleotides.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Alprostadil; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Female; Humans; Isoproterenol; Muscle, Smooth; Nitroprusside; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Piperazines; Purines; Rabbits; Sildenafil Citrate; Sulfones; Vagina; Vasoactive Intestinal Peptide; Vasodilator Agents | 1999 |
Cyclic GMP and outer hair cell electromotility.
Topics: Adenylyl Cyclases; Animals; Cell Movement; Colforsin; Cyclic GMP; Dibutyryl Cyclic GMP; Electric Stimulation; Enzyme Activation; Guinea Pigs; Hair Cells, Auditory, Outer; In Vitro Techniques; Phosphorylation; Protein Kinase C; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1999 |
Influence of increase in osmotic pressure with sucrose on relaxation and cyclonucleotides levels in isolated rat aorta.
Topics: Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Hypertonic Solutions; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Osmotic Pressure; Pinacidil; Rats; Rats, Sprague-Dawley; Sucrose; Vasodilator Agents | 1999 |
Autoregulation of nitric oxide-soluble guanylate cyclase-cyclic GMP signalling in mouse thoracic aorta.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta, Thoracic; Colforsin; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Guanylate Cyclase; Homeostasis; Indazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrogen Oxides; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Aggregation Inhibitors; Purinones; Spermine | 1999 |
A flavoprotein mechanism appears to prevent an oxygen-dependent inhibition of cGMP-associated nitric oxide-elicited relaxation of bovine coronary arteries.
Topics: Animals; Biphenyl Compounds; Cattle; Colforsin; Coronary Vessels; Cyclic GMP; Flavoproteins; Guanylate Cyclase; Hemeproteins; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Onium Compounds; Oxidation-Reduction; Oxidoreductases; Oxygen; Sulfates | 1999 |
NADPH and heme redox modulate pulmonary artery relaxation and guanylate cyclase activation by NO.
Topics: Animals; Cattle; Colforsin; Cyclic GMP; Electron Transport; Enzyme Activation; Enzyme Inhibitors; Ferricyanides; Flavoproteins; Glutathione; Guanylate Cyclase; Heme; In Vitro Techniques; NADH, NADPH Oxidoreductases; NADP; Nitric Oxide; Oxadiazoles; Oxidation-Reduction; Penicillamine; Pentose Phosphate Pathway; Pulmonary Artery; Quinoxalines; Reactive Oxygen Species; Sulfhydryl Compounds | 1999 |
Effect of adenylyl cyclase activation on intracellular and extracellular cAMP and cGMP in preimplantation cattle blastocysts.
Topics: Adenylyl Cyclases; Animals; Blastocyst; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Extracellular Space; Female; Gestational Age; Intracellular Fluid; Nucleotides, Cyclic; Stimulation, Chemical | 1999 |
Effects of sildenafil on cAMP and cGMP levels in isolated human cavernous and cardiac tissue.
Topics: Colforsin; Cyclic AMP; Cyclic GMP; Heart; Humans; In Vitro Techniques; Male; Milrinone; Myocardium; Penis; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones | 2000 |
Vasopressin regulates endothelin-B receptor in rat inner medullary collecting duct.
Topics: Animals; Arginine Vasopressin; Colforsin; Cyclic AMP; Cyclic GMP; Endothelin-1; Kidney Medulla; Kidney Tubules, Collecting; Male; Rats; Rats, Wistar; Receptor, Endothelin B; Receptors, Endothelin; RNA, Messenger; Thionucleotides; Time Factors; Vasopressins | 2000 |
The role of cyclic nucleotides in the spontaneous contractility and responsiveness to nitric oxide of the rat uterus at midgestation and term.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Female; Guanylate Cyclase; In Vitro Techniques; Myometrium; Nitric Oxide; Papaverine; Phosphodiesterase Inhibitors; Pregnancy; Rats; Rats, Sprague-Dawley; Uterine Contraction; Uterus | 2000 |
Effect of zaldaride maleate, an antidiarrheal compound, on intracellular cyclic nucleotide-mediated intestinal ion secretion in rats.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Anti-Ulcer Agents; Antidiarrheals; Benzimidazoles; Calmodulin; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Intestinal Mucosa; Ion Channels; Male; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 2000 |
Nitric oxide modulates expression of cell cycle regulatory proteins: a cytostatic strategy for inhibition of human vascular smooth muscle cell proliferation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aorta; Blood Platelets; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Division; Cell Line; Colforsin; Cyclic GMP; Cyclin A; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Genetic Therapy; Guanylate Cyclase; Humans; Hydrazines; Microtubule-Associated Proteins; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrogen Oxides; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins p21(ras); Transfection; Tumor Suppressor Proteins | 2000 |
A(2A) adenosine receptor mediated potassium channel activation in rat epididymal smooth muscle.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Diazoxide; Enzyme Activation; Epididymis; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Phenylephrine; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Endoplasmic reticulum contribution to the relaxant effect of cGMP- and cAMP-elevating agents in feline aorta.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Calcium-Binding Proteins; Cats; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Endoplasmic Reticulum; Enzyme Activation; In Vitro Techniques; Isoproterenol; Nitroprusside; Phosphorylation; Vasodilation | 2000 |
Relaxation of human ureteral smooth muscle in vitro by modulation of cyclic nucleotide-dependent pathways.
Topics: Colforsin; Cyclic AMP; Cyclic GMP; Humans; In Vitro Techniques; Isoquinolines; Muscle, Smooth; Nitroprusside; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperidines; Platelet Aggregation Inhibitors; Potassium Chloride; Purinones; Quinazolines; Rolipram; Tetrahydroisoquinolines; Ureter; Vasodilator Agents | 2000 |
Effects of N(G)-monomethyl-L-arginine on Ca(2+) current and nitric-oxide synthase in rat ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Calcium Channels, L-Type; Colforsin; Cyclic GMP; Enzyme Inhibitors; Milrinone; NADPH Dehydrogenase; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Rats | 2000 |
KT5823 inhibits cGMP-dependent protein kinase activity in vitro but not in intact human platelets and rat mesangial cells.
Topics: Alkaloids; Animals; Blood Platelets; Carbazoles; Cattle; Cell Adhesion Molecules; Colforsin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Glomerular Mesangium; Humans; Indoles; Isoquinolines; Microfilament Proteins; Nitric Oxide; Phosphoproteins; Phosphorylation; Rats; Sulfonamides | 2000 |
Regulation of pacemaker currents in interstitial cells of Cajal from murine small intestine by cyclic nucleotides.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Electric Conductivity; Gastrointestinal Motility; Guanylate Cyclase; Intestine, Small; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitroprusside; Nucleotides, Cyclic; Patch-Clamp Techniques; Phosphodiesterase Inhibitors | 2000 |
Functional characteristics of urinary tract smooth muscles in mice lacking cGMP protein kinase type I.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbachol; Cholinergic Agonists; Colforsin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Electric Stimulation; Female; Gene Expression Regulation, Enzymologic; Immunohistochemistry; Male; Mice; Mice, Knockout; Muscle Contraction; Muscle, Smooth; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Urethra; Urinary Bladder | 2000 |
gamma-tocopherol partially protects insulin-secreting cells against functional inhibition by nitric oxide.
Topics: Adenylyl Cyclases; Animals; Calcium; Calcium Channels; Carbachol; Cell Division; Cell Line; Cell Survival; Cholinergic Agonists; Colforsin; Cyclic GMP; Enzyme Inhibitors; Insulin; Insulin Secretion; Insulinoma; Interleukin-1; Islets of Langerhans; Models, Chemical; Nitric Oxide; Nitrogen Oxides; Oxadiazoles; Phorbol Esters; Protein Kinase C; Quinoxalines; Rats; Spermine; Type C Phospholipases; Vitamin E | 2000 |
Activation of the human, intermediate-conductance, Ca2+-activated K+ channel by methylxanthines.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Caffeine; Calcium; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electric Conductivity; Enzyme Inhibitors; Gene Expression; Humans; Magnesium; Membrane Potentials; Nitroprusside; Patch-Clamp Techniques; Potassium Channels; Recombinant Proteins; Theophylline; Transfection; Xanthines | 2000 |
Parathyroid hormone potentiates nucleotide-induced [Ca2+]i release in rat osteoblasts independently of Gq activation or cyclic monophosphate accumulation. A mechanism for localizing systemic responses in bone.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Animals; Calcium; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic GMP; Gene Expression; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Osteoblasts; Parathyroid Hormone; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Purinergic P2 Receptor Agonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1 | 2001 |
Effects of hyperprolactinemia on testosterone production in rat Leydig cells.
Topics: Animals; Colforsin; Cyclic GMP; Hyperprolactinemia; Leydig Cells; Male; Prolactin; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Testosterone | 2001 |
The effects of phosphodiesterase inhibition on cyclic GMP and cyclic AMP accumulation in the hippocampus of the rat.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Caffeine; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Guanylate Cyclase; Hippocampus; Image Processing, Computer-Assisted; Immunohistochemistry; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Norepinephrine; Phosphodiesterase Inhibitors; Purinones; Radioimmunoassay; Rats; Signal Transduction | 2001 |
Inhibitory effect of valves on endothelium-dependent relaxations to calcium ionophore in canine saphenous vein.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcimycin; Calcium; Colforsin; Cyclic GMP; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hydrazines; In Vitro Techniques; Indomethacin; Ionophores; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Potassium Chloride; Quinoxalines; Saphenous Vein; Vasoconstrictor Agents; Vasodilation | 2001 |
Vascular beta-adrenergic receptor system is dysfunctional after myocardial infarction.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Aorta; Aurora Kinases; Blood Pressure; Carotid Arteries; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; GTP-Binding Proteins; Heart Failure; In Vitro Techniques; Isoproterenol; Ligation; Muscle, Smooth, Vascular; Myocardial Infarction; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Ventricular Pressure | 2001 |
Inhibitory effects of nitric oxide on estrogen production and cAMP levels in rat granulosa cell cultures.
Topics: Animals; Aromatase; Cell Culture Techniques; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Estrogens; Female; Follicle Stimulating Hormone; Granulosa Cells; Nitric Oxide; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Vasodilator Agents | 2001 |
Interaction between the opposing functional effects of cyclic AMP and cyclic GMP in hypertrophic cardiac myocytes.
Topics: Animals; Cardiomegaly; Cell Separation; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Hypertension, Renovascular; Myocardial Contraction; Myocardium; Rabbits; Reference Values | 2001 |
Involvement of cyclic GMP in nitric-oxide-induced gastric relaxation Comparison of the actions of cyclic GMP and cyclic AMP.
Topics: Acetylcholine; Animals; Cats; Colforsin; Cyclic AMP; Cyclic GMP; Female; Inositol Phosphates; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitroprusside; Stomach | 2001 |
Effects of short- and long-term exposure to c-AMP and c-GMP on the noradrenaline transporter.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biological Transport; Bucladesine; Carrier Proteins; Cholera Toxin; Colforsin; COS Cells; Cyclic AMP; Cyclic GMP; Humans; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; PC12 Cells; Rats; RNA, Messenger; Staurosporine; Symporters; Time Factors; Tumor Cells, Cultured | 2001 |
Evaluation of islet heme oxygenase-CO and nitric oxide synthase-NO pathways during acute endotoxemia.
Topics: Animals; Blood Glucose; Carbon Monoxide; Colforsin; Cyclic AMP; Cyclic GMP; Endotoxemia; Female; Glucagon; Glucose; Heme Oxygenase (Decyclizing); In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Lipopolysaccharides; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Salmonella typhimurium; Time Factors | 2001 |
SQ22536 and W-7 inhibit forskolin-induced cAMP elevation but not relaxation in newborn ovine pulmonary veins.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenylyl Cyclases; Animals; Animals, Newborn; Cell Membrane; Colforsin; Cyclic AMP; Cyclic GMP; Endothelin-1; Enzyme Induction; Female; Male; Muscle, Smooth, Vascular; Pulmonary Veins; Sheep; Sulfonamides; Thionucleotides; Time Factors; Vasodilation | 2001 |
Site-specific phosphorylation and point mutations of telokin modulate its Ca2+-desensitizing effect in smooth muscle.
Topics: Amino Acid Substitution; Animals; Aspartic Acid; Binding Sites; Calcium; Colforsin; Culture Techniques; Cyclic GMP; Ileum; Microcystins; Microscopy, Electron; Muscle Proteins; Muscle Relaxation; Muscle, Smooth; Myosin-Light-Chain Kinase; Peptide Fragments; Peptides; Peptides, Cyclic; Phosphorylation; Point Mutation; Rabbits; Serine | 2001 |
Nitric oxide decreases pacemaker activity in lymphatic vessels of guinea pig mesentery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Biological Clocks; Calcium; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Glyburide; Guinea Pigs; In Vitro Techniques; Lymphatic System; Male; Membrane Potentials; Mesentery; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Vasodilator Agents | 2001 |
cAMP modulates the excitability of immortalized H=hypothalamic (GT1) neurons via a cyclic nucleotide gated channel.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Diltiazem; Enzyme Inhibitors; Hypothalamus; Ion Channels; Isoquinolines; Microscopy, Fluorescence; Microscopy, Video; Neurons; Patch-Clamp Techniques; Sulfonamides | 2001 |
Regulation of anion secretion by nitric oxide in human airway epithelial cells.
Topics: Anions; Benzimidazoles; Bronchi; Calcium Channel Agonists; Cell Line; Colforsin; Cyclic GMP; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Glutathione; Humans; Ion Channels; Nitric Oxide; Nitric Oxide Synthase; Nitroso Compounds; Respiratory Mucosa; S-Nitrosoglutathione | 2001 |
Cardiac phosphodiesterase 5 (cGMP-specific) modulates beta-adrenergic signaling in vivo and is down-regulated in heart failure.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blood Pressure; Cardiac Output, Low; Colforsin; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dobutamine; Dogs; Female; Heart; Hemodynamics; Immunohistochemistry; Male; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Piperazines; Purines; Purinones; Pyrazoles; Receptors, Adrenergic, beta; Signal Transduction; Sildenafil Citrate; Sulfones | 2001 |
Cyclic nucleotide-mediated regulation of hippocampal mossy fiber development: a target-specific guidance.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Animals, Newborn; Axons; Cell Culture Techniques; Cells, Cultured; Coculture Techniques; Colforsin; Cyclic AMP; Cyclic GMP; Dendrites; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Fibrinolysin; Growth Cones; Hippocampus; Membrane Potentials; Mossy Fibers, Hippocampal; Nucleotides, Cyclic; Presynaptic Terminals; Rats; Rats, Wistar; Signal Transduction | 2001 |
Selected contribution: HSP20 phosphorylation in nitroglycerin- and forskolin-induced sustained reductions in swine carotid media tone.
Topics: Animals; Calcium; Carotid Artery, Common; Colforsin; Cyclic AMP; Cyclic GMP; Heat-Shock Proteins; HSP20 Heat-Shock Proteins; In Vitro Techniques; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Phosphoproteins; Phosphorylation; Signal Transduction; Swine; Vasodilator Agents | 2001 |
Coordinate regulation of endothelin and adrenomedullin secretion by oxidative stress in endothelial cells.
Topics: Adrenomedullin; Animals; Antibodies, Monoclonal; Antioxidants; Calcium; Carotid Arteries; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelin-1; Endothelins; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; Ionophores; Oxidants; Oxidative Stress; Peptides; RNA, Messenger | 2001 |
cGMP-mediated inhibition of cardiac L-type Ca(2+) current by a monoclonal antibody against the M(2) ACh receptor.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Antibodies, Monoclonal; Autoantibodies; Calcium Channels, L-Type; Colforsin; Cyclic GMP; Enzyme Inhibitors; Guanosine; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Membrane Potentials; Muscle Fibers, Skeletal; Myocardium; Oxadiazoles; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Quinoxalines; Receptor, Muscarinic M2; Receptors, Muscarinic | 2001 |
Nitric oxide is required for the induction and heterosynaptic spread of long-term potentiation in rat cerebellar slices.
Topics: Algorithms; Animals; Cerebellum; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic N-Oxides; Electrophysiology; Free Radical Scavengers; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Long-Term Potentiation; Male; Neuronal Plasticity; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Patch-Clamp Techniques; Purkinje Cells; Rats; Rats, Wistar; Synapses | 2001 |
Nitric oxide inhibition of cAMP synthesis in parotid acini: regulation of type 5/6 adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoenzymes; Isoproterenol; Mice; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Parotid Gland; Phosphoric Diester Hydrolases; Quinoxalines; Thapsigargin; Triazoles | 2001 |
Nitric oxide-induced F-actin disassembly is mediated via cGMP, cAMP, and protein kinase A activation in rat mesangial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Actins; Animals; Cell Size; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glomerular Mesangium; Nitric Oxide; Nitric Oxide Donors; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats; Renal Circulation; Signal Transduction | 2001 |
Expression of inducible nitric oxide synthase depresses beta-adrenergic-stimulated calcium release from the sarcoplasmic reticulum in intact ventricular myocytes.
Topics: Animals; Calcium; Colforsin; Cyclic GMP; Enzyme Inhibitors; Guanidines; Guanylate Cyclase; Heart Failure; Heart Ventricles; Humans; Lipopolysaccharides; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum | 2001 |
PKC and PKA, but not PKG mediate LPS-induced CGRP release and [Ca(2+)](i) elevation in DRG neurons of neonatal rats.
Topics: Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Calcium; Carcinogens; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Ganglia, Spinal; Lipopolysaccharides; Male; Neurogenic Inflammation; Neurons, Afferent; Potassium; Protein Kinase C; Protein Kinases; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; Up-Regulation | 2001 |
Identification and functional study of phosphodiesterases in rat urinary bladder.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Female; Guanylate Cyclase; In Vitro Techniques; Isoenzymes; Male; Muscle Contraction; Nitric Oxide Donors; Nitroprusside; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats; Rats, Wistar; Urinary Bladder | 2001 |
PKA-dependent activation of PDE3A and PDE4 and inhibition of adenylyl cyclase V/VI in smooth muscle.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Dichlororibofuranosylbenzimidazole; Enzyme Activation; Enzyme Inhibitors; Isoenzymes; Isoproterenol; Muscle, Smooth; Phosphorylation; Rabbits; Stomach; Sympathomimetics; Thionucleotides | 2002 |
Lysophosphatidic acid stimulates proliferation of cultured smooth muscle cells from human BPH tissue: sildenafil and papaverin generate inhibition.
Topics: Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; DNA; Dose-Response Relationship, Drug; Growth Inhibitors; Humans; Lysophospholipids; Male; Muscle, Smooth; Papaverine; Phosphodiesterase Inhibitors; Piperazines; Prostatic Hyperplasia; Protein Biosynthesis; Proteins; Purines; Purinones; Sildenafil Citrate; Stimulation, Chemical; Sulfones | 2002 |
The mechanism of ciliary stimulation by acetylcholine: roles of calcium, PKA, and PKG.
Topics: Acetylcholine; Animals; Calcium; Calmodulin; Cilia; Colforsin; Culture Techniques; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Phosphorylation; Rana ridibunda; Respiratory Mucosa | 2002 |
Role of cyclic nucleotides in ischemia and reperfusion injury of canine livers.
Topics: Adenosine Triphosphate; Amrinone; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Energy Metabolism; Female; Hemodynamics; Ischemia; Liver; Liver Circulation; Platelet Count; Portal Vein; Reperfusion Injury | 2002 |
Control of renin secretion from rat juxtaglomerular cells by cAMP-specific phosphodiesterases.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Isoproterenol; Isoquinolines; Juxtaglomerular Apparatus; Membrane Potentials; Mice; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Renin; Tetrahydroisoquinolines; Thionucleotides | 2002 |
Effects of various nitric oxide donating agents on the contractility and cyclic nucleotide turnover of human seminal vesicles in vitro.
Topics: Aged; Colforsin; Cyclic AMP; Cyclic GMP; Electric Stimulation; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nitric Oxide Donors; Seminal Vesicles | 2002 |
Akt pathway mediates a cGMP-dependent survival role of nitric oxide in cerebellar granule neurones.
Topics: Animals; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspase Inhibitors; Cell Differentiation; Cell Survival; Cells, Cultured; Cerebellum; Colforsin; Cyclic GMP; Enzyme Inhibitors; Gene Expression; Glycogen Synthase Kinase 3; Insulin; Lithium; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction | 2002 |
Attenuation of cAMP accumulation in adult rat cardiac fibroblasts by IL-1beta and NO: role of cGMP-stimulated PDE2.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 2; Enzyme Induction; Fibroblasts; Guanylate Cyclase; Interleukin-1; Isoproterenol; Male; Myocardium; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Phosphoric Diester Hydrolases; Rats; Rats, Sprague-Dawley | 2002 |
Early activation of the p42/p44MAPK pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism.
Topics: Adenosine; Androstadienes; Arginine; Biological Transport; Butadienes; Calcium; Cells, Cultured; Chromones; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Fetus; Flavonoids; Gene Expression; Genistein; Humans; Hydrogen-Ion Concentration; MAP Kinase Signaling System; Membrane Potentials; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitriles; Phenethylamines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Potassium; Protein Isoforms; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Wortmannin | 2002 |
Bullatacin, a potent antitumor Annonaceous acetogenin, induces apoptosis through a reduction of intracellular cAMP and cGMP levels in human hepatoma 2.2.15 cells.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Colforsin; Cyclic AMP; Cyclic GMP; Drug Interactions; Fluorescein-5-isothiocyanate; Furans; Humans; S-Nitrosoglutathione; Tumor Cells, Cultured | 2003 |
cAMP activates BKCa channels in pulmonary arterial smooth muscle via cGMP-dependent protein kinase.
Topics: Alkaloids; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Hypertrophy, Right Ventricular; Indoles; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Large-Conductance Calcium-Activated Potassium Channels; Male; Membrane Potentials; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Platelet Aggregation Inhibitors; Potassium Channels, Calcium-Activated; Pulmonary Artery; Rats; Rats, Inbred Strains; Thionucleotides; Vasodilator Agents | 2003 |
Differential regulation of P-selectin expression by protein kinase A and protein kinase G in thrombin-stimulated human platelets.
Topics: Adenylyl Cyclases; Alkaloids; Blood Platelets; Carbazoles; Cell Adhesion; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Indoles; Isoquinolines; Neutrophils; P-Selectin; Phosphorylation; Platelet Activation; Protein Processing, Post-Translational; Second Messenger Systems; Sulfonamides; Thrombin | 2003 |
Presynaptic cyclic nucleotide-gated ion channels modulate neurotransmission in the mammalian olfactory bulb.
Topics: Animals; Calcium; Colforsin; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Agonists; In Vitro Techniques; Ion Channel Gating; Ion Channels; Mice; Mice, Inbred C57BL; Nucleotides, Cyclic; Olfactory Bulb; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2003 |
Effects of various nitric oxide-donating drugs on adrenergic tension of human seminal vesicles in vitro.
Topics: Adrenergic alpha-Agonists; Aged; Colforsin; Cyclic GMP; Ejaculation; Erectile Dysfunction; Humans; In Vitro Techniques; Isometric Contraction; Male; Middle Aged; Molsidomine; Muscle Contraction; Muscle, Smooth; Nitric Oxide Donors; Nitroprusside; Norepinephrine; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Seminal Vesicles; Sexual Dysfunction, Physiological; Signal Transduction | 2003 |
Effects of nitric oxide and cGMP on inhibin A and inhibin subunit mRNA levels from cultured rat granulosa cells.
Topics: Animals; Blotting, Northern; Colforsin; Cyclic GMP; Dibutyryl Cyclic GMP; Enzyme Inhibitors; Estradiol; Female; Follicle Stimulating Hormone; Granulosa Cells; Inhibins; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2003 |
Heme oxygenase-mediated vasodilation involves vascular smooth muscle cell hyperpolarization.
Topics: Animals; Biliverdine; Calcium Signaling; Carbon Monoxide; Cell Membrane; Colforsin; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Heme; Heme Oxygenase (Decyclizing); Large-Conductance Calcium-Activated Potassium Channels; Lysine; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Potassium Channels, Calcium-Activated; Rats; Rats, Sprague-Dawley; Ryanodine; Vascular Resistance; Vasodilation | 2003 |
Phosphodiesterase 3 activity is reduced in dog lung following pacing-induced heart failure.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Capillaries; Capillary Permeability; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Dogs; Heart Failure; Hydrolysis; Lung; Pacemaker, Artificial; Phosphodiesterase Inhibitors; Pulmonary Circulation; Quinolones; Reverse Transcriptase Polymerase Chain Reaction | 2003 |
Inhibition of ovarian steroidogenesis by cyclic GMP in a fly.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Alkaloids; Animals; Brain; Calcium Channels; Carbazoles; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Diptera; Ecdysteroids; Female; Indoles; Organ Culture Techniques; Ovary; Phosphodiesterase Inhibitors; Quinazolines; Signal Transduction; Stimulation, Chemical | 2003 |
MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine.
Topics: Adenine; Adenosine Triphosphate; Animals; Antineoplastic Agents; Antiviral Agents; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Cell Membrane; Colforsin; Coloring Agents; Cyclic AMP; Cyclic GMP; DNA, Complementary; Dose-Response Relationship, Drug; Drug Resistance; Floxuridine; Fluorouracil; Genetic Vectors; Growth Inhibitors; Immunoblotting; Inhibitory Concentration 50; Insecta; Models, Biological; Nitrosamines; Nucleotides; Organophosphonates; Swine; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Zalcitabine | 2003 |
Testosterone inhibits the prostaglandin F2alpha-mediated increase in intracellular calcium in A7r5 aortic smooth muscle cells: evidence of an antagonistic action upon store-operated calcium channels.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Line; Chelating Agents; Colforsin; Cyclic AMP; Cyclic GMP; Dideoxynucleosides; Dinoprost; Flow Cytometry; Imidazoles; Indoles; Intracellular Fluid; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide Donors; Nitroprusside; Testosterone; Verapamil | 2003 |
Receptor-controlled phosphorylation of alpha 1 soluble guanylyl cyclase enhances nitric oxide-dependent cyclic guanosine 5'-monophosphate production in pituitary cells.
Topics: Alanine; Amino Acid Substitution; Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dimerization; Enzyme Activation; Enzyme Inhibitors; Female; Growth Hormone-Releasing Hormone; Guanylate Cyclase; Neuropeptides; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland, Anterior; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Neuropeptide; Receptors, Pituitary Hormone-Regulating Hormone; Serine; Soluble Guanylyl Cyclase; Vasoactive Intestinal Peptide | 2004 |
Pertussis toxin-sensitive G protein but not NO/cGMP pathway mediates the negative inotropic effect of carbachol in adult rat cardiomyocytes.
Topics: Adenylyl Cyclases; Animals; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Electric Stimulation; GTP-Binding Proteins; Injections, Intraperitoneal; Isoproterenol; Male; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide Synthase; omega-N-Methylarginine; Oxadiazoles; Pertussis Toxin; Quinoxalines; Rats; Time Factors | 2004 |
Correlation between spontaneous electrical, calcium and mechanical activity in detrusor smooth muscle of the guinea-pig bladder.
Topics: Action Potentials; Amides; Animals; Apamin; Boron Compounds; Calcium; Calcium Signaling; Carbachol; Charybdotoxin; Colforsin; Cromakalim; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Female; Fura-2; Guinea Pigs; Isotonic Contraction; Male; Mechanotransduction, Cellular; Microelectrodes; Muscle Contraction; Muscle, Smooth; Nifedipine; Pyridines; Transducers; Urinary Bladder | 2004 |
Negative regulation of gamma-globin gene expression by cyclic AMP-dependent pathway in erythroid cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenylyl Cyclases; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Erythroid Precursor Cells; Gene Expression Regulation; Globins; Hemin; Humans; K562 Cells; MAP Kinase Signaling System; Phosphorylation; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Transcription, Genetic | 2004 |
Adrenomedullin affects two signal transduction pathways and the migration in retinal pigment epithelial cells.
Topics: Adrenomedullin; Aniline Compounds; Calcium; Calcium Signaling; Cell Adhesion; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Down-Regulation; Humans; Immunoenzyme Techniques; Microscopy, Confocal; NG-Nitroarginine Methyl Ester; Peptides; Pigment Epithelium of Eye; Second Messenger Systems; Up-Regulation; Vasodilator Agents; Xanthenes | 2004 |
Cyclic adenosine monophosphate (cAMP) increases natriuretic peptide receptor C (NPR-C) expression in human aortic smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Aorta; Atrial Natriuretic Factor; Bucladesine; Carbazoles; Cell Culture Techniques; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Guanylate Cyclase; Humans; Indoles; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Binding; Pyrroles; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Signal Transduction | 2004 |
cAMP modulates cGMP-mediated cerebral arteriolar relaxation in vivo.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arterioles; Cerebrovascular Circulation; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Enzyme Activators; Hydrolysis; Indazoles; Male; Multidrug Resistance-Associated Proteins; Nitric Oxide; Nitric Oxide Donors; Phosphoric Diester Hydrolases; Rats; Rats, Sprague-Dawley; Vasodilation | 2004 |
Circadian and cAMP-dependent modulation of retinal cone cGMP-gated channels does not require protein synthesis or calcium influx through L-type channels.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Chick Embryo; Circadian Rhythm; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Ion Channel Gating; Ion Channels; Light Signal Transduction; Nitrendipine; Patch-Clamp Techniques; Retinal Cone Photoreceptor Cells | 2004 |
Effects of various selective phosphodiesterase inhibitors on carbachol-induced contraction and cyclic nucleotide contents in guinea pig taenia coli.
Topics: Adenine; Animals; Carbachol; Colforsin; Colon; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Male; Milrinone; Muscle Contraction; Nitroprusside; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Purinones; Vinca Alkaloids | 2004 |
Modulation of NMDA receptor function by cyclic AMP in cerebellar neurones in culture.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cells, Cultured; Cerebellum; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Intracellular Fluid; Nerve Growth Factors; Neurons; Neuropeptides; Neurotransmitter Agents; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2004 |
Heat-stable enterotoxin of Escherichia coli stimulates a non-CFTR-mediated duodenal bicarbonate secretory pathway.
Topics: Animals; Bacterial Toxins; Benzoquinones; Bicarbonates; Cell Membrane; Chloride-Bicarbonate Antiporters; Colforsin; Cyclic GMP; Cystic Fibrosis; Duodenum; Enterotoxins; Enzyme Inhibitors; Escherichia coli Proteins; Genistein; In Vitro Techniques; Lactams, Macrocyclic; Mice; Natriuretic Peptides; Peptides; Protein-Tyrosine Kinases; Quinones; Rifabutin | 2005 |
Chronic hyperalgesic priming in the rat involves a novel interaction between cAMP and PKCepsilon second messenger pathways.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Analysis of Variance; Animals; Behavior, Animal; Carrageenan; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hyperalgesia; Male; Models, Biological; Pain Measurement; Pain Threshold; Protein Kinase C; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Thionucleotides | 2005 |
Atrial natriuretic peptide inhibits the actions of FSH and forskolin in meiotic maturation of pig oocytes via different signalling pathways.
Topics: Animals; Atrial Natriuretic Factor; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Female; Follicle Stimulating Hormone; Humans; Meiosis; Mitogen-Activated Protein Kinases; Oocytes; Phosphorylation; Swine | 2005 |
Modulation of voltage-dependent Ba2+ currents in the guinea-pig gastric antrum by cyclic nucleotide-dependent pathways.
Topics: Animals; Barium; Bucladesine; Calcium Channels, L-Type; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Myocytes, Smooth Muscle; Peptides; Pyloric Antrum; Thionucleotides | 2005 |
Involvement of guanylyl cyclase, protein kinase A and Na+ K+ ATPase in relaxations of bovine isolated bronchioles induced by GEA 3175, an NO donor.
Topics: Animals; Bronchi; Calcium; Cattle; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Guanylate Cyclase; In Vitro Techniques; Molsidomine; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Ouabain; Oxadiazoles; Peptides; Potassium; Quinoxalines; S-Nitrosoglutathione; Serotonin; Sodium-Potassium-Exchanging ATPase; Thionucleotides; Triazoles | 2006 |
Cyclic nucleotide kinases and tachyzoite-bradyzoite transition in Toxoplasma gondii.
Topics: 1-Methyl-3-isobutylxanthine; Animals; beta-Galactosidase; Cell Differentiation; Chloramphenicol O-Acetyltransferase; Colforsin; Culture Media; Cyclic AMP; Cyclic GMP; Gene Expression Regulation, Developmental; Genes, Protozoan; Genes, Reporter; Heat-Shock Proteins; Life Cycle Stages; Nitroprusside; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Protozoan Proteins; Signal Transduction; Toxoplasma; Toxoplasmosis; Tubulin | 2006 |
Effect of IPs, cAMP, and cGMP on the hPL and hCG secretion from human term placenta.
Topics: Chorionic Gonadotropin; Colforsin; Cyclic AMP; Cyclic GMP; Female; Humans; In Vitro Techniques; Inositol Phosphates; Nitroprusside; Placenta; Placental Lactogen; Pregnancy; Signal Transduction; Sodium Fluoride | 2005 |
Rapid modulatory effect of estradiol on acetylcholine-induced Ca2+ signal is mediated through cyclic-GMP cascade in LHRH-releasing GT1-7 cells.
Topics: Acetylcholine; Animals; Autoradiography; Calcium; Calcium Channels; Cell Line; Colforsin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Drug Interactions; Estradiol; Gonadotropin-Releasing Hormone; Inositol 1,4,5-Trisphosphate Receptors; Mice; Models, Biological; Natriuretic Peptides; Neurons; Nitric Oxide Donors; Nitroprusside; Phosphorylation; Receptors, Cytoplasmic and Nuclear | 2005 |
Absence of force suppression in rabbit bladder correlates with low expression of heat shock protein 20.
Topics: Adenylyl Cyclases; Animals; Carbachol; Carotid Arteries; Colforsin; Cyclic GMP; Enzyme Activation; HSP20 Heat-Shock Proteins; Immunologic Techniques; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Myosin Light Chains; Phosphorylation; Rabbits; Staining and Labeling; Swine; Urinary Bladder | 2005 |
Stimulation of soluble guanylyl cyclase by BAY 41-2272 relaxes anococcygeus muscle: interaction with nitric oxide.
Topics: Animals; Carbachol; Carbolines; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroglycerin; Oxadiazoles; Pyrazoles; Pyridines; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Tadalafil; Tetrodotoxin | 2006 |
Nitric oxide production from rat adipocytes is modulated by beta3-adrenergic receptor agonists and is involved in a cyclic AMP-dependent lipolysis in adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenylyl Cyclase Inhibitors; Adipocytes; Adrenergic Agonists; Adrenergic beta-3 Receptor Agonists; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Lipolysis; Male; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine | 2006 |
Convergence of Ca2+-desensitizing mechanisms activated by forskolin and phenylephrine pretreatment, but not 8-bromo-cGMP.
Topics: Animals; Blotting, Western; Calcium; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Femoral Artery; Muscle Contraction; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Phenylephrine; Phosphorylation; Potassium Chloride; Rabbits; Vasoconstrictor Agents | 2006 |
Ca2+-activated K+ (KCa) channels are involved in the relaxations elicited by sildenafil in penile resistance arteries.
Topics: Animals; Arteries; Charybdotoxin; Colforsin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Horses; In Vitro Techniques; Male; Nitric Oxide Donors; Penis; Peptides; Piperazines; Potassium; Potassium Channels, Calcium-Activated; Purines; S-Nitroso-N-Acetylpenicillamine; Sildenafil Citrate; Sulfones; Tetraethylammonium; Thionucleotides; Vascular Resistance; Vasodilation; Vasodilator Agents | 2006 |
Regulation of protein synthesis in Y-organs of the blue crab (Callinectes sapidus): involvement of cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Autoradiography; Brachyura; Bucladesine; Colforsin; Cyclic AMP; Cyclic GMP; Cycloheximide; Ecdysteroids; Electrophoresis, Polyacrylamide Gel; Endocrine Glands; Methionine; Protein Biosynthesis; Signal Transduction; Time Factors | 2006 |
[In vitro effects of cAMP- and cGMP-stimulating drugs on the relaxation of the prostate smooth muscle tissue contraction induced by endothelin-1].
Topics: Adenylyl Cyclases; Aged; Angiotensin II; Colforsin; Cyclic AMP; Cyclic GMP; Endothelin-1; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth; Nitric Oxide Donors; Nitroprusside; Prostate; S-Nitrosoglutathione; Signal Transduction | 2006 |
Modulation of NMDA receptors by AKT kinase.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Cerebellum; Colforsin; Cyclic GMP; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Immunoblotting; Immunoprecipitation; N-Methylaspartate; Neurons; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2006 |
Dependence of electrical activity and calcium influx-controlled prolactin release on adenylyl cyclase signaling pathway in pituitary lactotrophs.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Calcium; Calcium Channels; Cell Membrane Permeability; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Electron Transport; Electrophysiology; Enzyme Inhibitors; Female; Ion Channel Gating; Patch-Clamp Techniques; Phosphoric Diester Hydrolases; Pituitary Gland; Prolactin; Rats; Rats, Sprague-Dawley; Signal Transduction | 2006 |
Role of cyclic nucleotides in fetal hemoglobin induction in cultured CD34+ cells.
Topics: Adenylyl Cyclases; Antigens, CD34; Antisickling Agents; Azacitidine; Butyrates; Colforsin; Cyclic AMP; Cyclic GMP; Decitabine; Enzyme Inhibitors; Erythroid Cells; Fetal Hemoglobin; Humans; Hydroxyurea; K562 Cells; Monocytes; RNA, Messenger | 2006 |
Regulation of human internal mammary and radial artery contraction by extracellular and intracellular calcium channels and cyclic adenosine 3', 5' monophosphate.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenylyl Cyclases; Calcium; Calcium Channels; Colforsin; Cyclic AMP; Cyclic GMP; Extracellular Fluid; Humans; In Vitro Techniques; Intracellular Fluid; Isoproterenol; Mammary Arteries; Milrinone; Phenylephrine; Potassium Chloride; Radial Artery; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2007 |
Hydrogen sulfide inhibits human platelet aggregation.
Topics: Adult; Blood Platelets; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Hydrogen Sulfide; In Vitro Techniques; Nitric Oxide; Platelet Aggregation Inhibitors; Potassium Channels | 2007 |
NHE3 inhibition by cAMP and Ca2+ is abolished in PDZ-domain protein PDZK1-deficient murine enterocytes.
Topics: Adenylyl Cyclases; Animals; Calcium; Cation Transport Proteins; Colforsin; Colon; Cyclic AMP; Cyclic GMP; Enterocytes; Enzyme Activation; Enzyme Activators; Gene Expression; Hydrogen-Ion Concentration; Ionomycin; Ionophores; Membrane Proteins; Mice; Mice, Knockout; Microvilli; Osmolar Concentration; Ribonucleoproteins; Sodium; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2007 |
Regulation of the Na+/Ca2+ exchanger (NCX) in the murine embryonic heart.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Fetal Development; Gestational Age; Heart; Heart Ventricles; Indoles; Mice; Myocytes, Cardiac; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Pyrroles; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate | 2007 |
Regulation of protease-activated receptor (PAR) 1 and PAR4 signaling in human platelets by compartmentalized cyclic nucleotide actions.
Topics: 1-Methyl-3-isobutylxanthine; Blood Platelets; Bucladesine; Calcium; Cell Adhesion Molecules; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Indazoles; Kinetics; Microfilament Proteins; Nucleotides, Cyclic; Oligopeptides; Peptide Fragments; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptor, PAR-1; Receptors, Thrombin; Signal Transduction; Thionucleotides; Thrombin | 2007 |
Cyclic AMP dependent down regulation in the relaxation of smooth muscle cells of cat esophagitis.
Topics: Adenylyl Cyclases; Animals; Blotting, Western; Bucladesine; Cats; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Down-Regulation; Esophagitis; In Vitro Techniques; Isoenzymes; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide Donors; Nitroprusside; Signal Transduction; Vasoactive Intestinal Peptide | 2007 |
Potentiation of ATP- and bradykinin-induced [Ca2+]c responses by PTHrP peptides in the HaCaT cell line.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Bradykinin; Calcium; Carbazoles; Cell Division; Cell Line; Colforsin; Cyclic AMP; Cyclic GMP; Drug Synergism; Humans; Indoles; Keratinocytes; Parathyroid Hormone-Related Protein; Peptide Fragments; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Signal Transduction | 2008 |
Fenvalerate inhibits progesterone production through cAMP-dependent signal pathway.
Topics: Animals; Cell Line, Tumor; Cell Survival; Cholera Toxin; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxycholesterols; Insecticides; Leydig Cell Tumor; Male; Mice; Nitriles; Phosphoproteins; Pregnenolone; Progesterone; Pyrethrins; RNA, Messenger; Signal Transduction | 2008 |
Effect of hydrogen peroxide on VIP-induced relaxation of the cat lower esophageal sphincter.
Topics: Animals; Cats; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Esophageal Sphincter, Lower; Female; Guanosine 5'-O-(3-Thiotriphosphate); Hydrogen Peroxide; Male; Muscle Relaxation; Vasoactive Intestinal Peptide | 2007 |
PDE4 and PDE5 regulate cyclic nucleotides relaxing effects in human umbilical arteries.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 5; Dipyridamole; Female; Guanylate Cyclase; Histamine; Humans; In Vitro Techniques; Isoenzymes; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthyridines; Nitroprusside; Phosphodiesterase 4 Inhibitors; Phosphodiesterase 5 Inhibitors; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Rolipram; Serotonin; Umbilical Arteries; Vasodilator Agents | 2008 |
Role of vasodilator-stimulated phosphoprotein in cGMP-mediated protection of human pulmonary artery endothelial barrier function.
Topics: Colforsin; Cyclic GMP; Cyclosporine; Endothelium, Vascular; Humans; Hydrogen Peroxide; Kinetics; Phosphoproteins; Phosphoserine; Plasmids; Pulmonary Artery; RNA, Small Interfering; Transfection; Vasodilator Agents | 2008 |
Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Cell Line, Tumor; Colforsin; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide-Gated Cation Channels; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose; Guanylate Cyclase; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Melatonin; Pineal Gland; Rats; Rats, Wistar; Receptor, Melatonin, MT2; Signal Transduction; Tetrahydronaphthalenes; Tryptamines | 2008 |
Antagonistic actions of S(-)-Bay K 8644 on cyclic nucleotide-induced inhibition of voltage-dependent Ba(2+) currents in guinea pig gastric antrum.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Bucladesine; Calcium Channel Agonists; Calcium Channels, L-Type; Colforsin; Cyclic GMP; Female; Guinea Pigs; In Vitro Techniques; Male; Myocytes, Smooth Muscle; Nitroprusside; Patch-Clamp Techniques; Pyloric Antrum; Stereoisomerism; Vasodilator Agents | 2008 |
The Galphai and Galphaq proteins mediate the effects of melatonin on steroid/thyroid hormone receptor transcriptional activity and breast cancer cell proliferation.
Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic GMP; Estrogens; Female; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Immunoprecipitation; Luciferases; Melatonin; Phosphorus Radioisotopes; Radioimmunoassay; Receptor, Melatonin, MT1; Receptors, Estrogen; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Retinoic Acid Receptor alpha; Transcription, Genetic; Transfection | 2008 |
Cyclic-AMP-dependent proliferation of a human osteoblast cell line (HOS cells) induced by hydroxyapatite: effect of exogenous nitric oxide.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Arginase; Cell Communication; Cell Differentiation; Cell Line; Colforsin; Colorimetry; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dichlororibofuranosylbenzimidazole; Durapatite; Guanylate Cyclase; Humans; Nitric Oxide; Nitric Oxide Donors; Osteoblasts; Penicillamine; Phosphodiesterase Inhibitors; Rolipram; S-Nitroso-N-Acetylpenicillamine | 2008 |
Involvement of phosphatidylinositol 3-kinase in cAMP- and cGMP-induced duodenal epithelial CFTR activation in mice.
Topics: Animals; Bicarbonates; Chlorides; Colforsin; Cyclic AMP; Cyclic GMP; Cystic Fibrosis Transmembrane Conductance Regulator; Duodenum; Epithelial Cells; Intestinal Mucosa; Mice; Mice, Knockout; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Signal Transduction; Staining and Labeling; Time Factors | 2009 |
Nitric oxide and cyclic nucleotide signal transduction modulates synaptic vesicle turnover in human model neurons.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Cell Differentiation; Cell Line, Tumor; Colforsin; Cyclic GMP; Enzyme Inhibitors; Exocytosis; Humans; Isoquinolines; Microtubule-Associated Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Nitroso Compounds; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Pyridinium Compounds; Quaternary Ammonium Compounds; Signal Transduction; Sulfonamides; Synapsins; Synaptic Vesicles; Synaptotagmin I; Teratocarcinoma; Time Factors | 2009 |
Nitric oxide and downstream second messenger cGMP and cAMP enhance adipogenesis in primary human preadipocytes.
Topics: Adenylyl Cyclase Inhibitors; Adipocytes; Adipogenesis; Adult; Cell Proliferation; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; DDT; Guanylate Cyclase; Humans; Male; Middle Aged; Nitric Oxide; Oxadiazoles; Quinoxalines; Second Messenger Systems; Stem Cells; Subcutaneous Fat; Tissue Engineering | 2010 |
HGF suppresses high glucose-mediated oxidative stress in mesangial cells by activation of PKG and inhibition of PKA.
Topics: Animals; Antioxidants; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Glucose; Glucosephosphate Dehydrogenase; Glutamate-Cysteine Ligase; Glutathione; Hepatocyte Growth Factor; Malondialdehyde; Mesangial Cells; Oxidative Stress; Rats; Thionucleotides | 2010 |
Grueneberg ganglion neurons are finely tuned cold sensors.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Calcium; Calcium Signaling; Cold Temperature; Colforsin; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Ganglia, Sensory; Green Fluorescent Proteins; In Vitro Techniques; Isothiocyanates; Mice; Mice, Transgenic; Microscopy, Confocal; Nasal Cavity; Olfactory Bulb; Olfactory Marker Protein; Olfactory Pathways; Phosphodiesterase Inhibitors; Pyrimidinones; Sensory Receptor Cells; Sodium Channel Blockers; Tetrodotoxin; Thermosensing; Time Factors; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2010 |
Long-term treatment with atrial natriuretic peptide inhibits ATP production and insulin secretion in rat pancreatic islets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Atrial Natriuretic Factor; Blotting, Western; Colforsin; Cyclic GMP; Enzyme-Linked Immunosorbent Assay; Glucose; In Vitro Techniques; Insulin; Islets of Langerhans; Keto Acids; Male; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2011 |
Exposure of human seminal vesicle tissue to phosphodiesterase (PDE) inhibitors antagonizes the contraction induced by norepinephrine and increases production of cyclic nucleotides.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Aged; Colforsin; Cyclic AMP; Cyclic GMP; Drug Evaluation, Preclinical; Ejaculation; Humans; In Vitro Techniques; Male; Milrinone; Muscle Relaxation; Nitroprusside; Norepinephrine; Phosphodiesterase Inhibitors; Piperazines; Purines; Receptors, Adrenergic, alpha; Rolipram; Seminal Vesicles; Sildenafil Citrate; Sulfones | 2010 |
Polystyrene nanoparticles activate ion transport in human airway epithelial cells.
Topics: Animals; Anions; Calcium Channels; Cell Line; Colforsin; Cricetinae; Cyclic GMP; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Epithelial Cells; Guanylate Cyclase; Humans; Ion Transport; Nanoparticles; Patch-Clamp Techniques; Polystyrenes; Potassium Channels; Respiratory Mucosa; Signal Transduction | 2011 |
Role of cGMP and cAMP in the hemodynamic response to intrathecal sildenafil administration.
Topics: Animals; Blood Pressure; Bucladesine; Colforsin; Cyclic GMP; Heart Rate; Injections, Spinal; Male; Piperazines; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Vasodilator Agents | 2011 |
Vasodilatory effect of pentoxifylline in isolated equine digital veins.
Topics: Animals; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Horses; Indomethacin; Nitroprusside; Pentoxifylline; Tissue Culture Techniques; Vasodilation; Vasodilator Agents; Veins | 2012 |
Renal actions of dendroaspis natriuretic peptide in rabbits.
Topics: Animals; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Elapid Venoms; Guanylate Cyclase; Intercellular Signaling Peptides and Proteins; Kidney; Male; Peptides; Rabbits | 2012 |
Effect of nitric oxide on epithelial ion transports in noncystic fibrosis and cystic fibrosis human proximal and distal airways.
Topics: Adenosine Triphosphate; Adult; Aged; Amiloride; Bronchi; Chloride Channels; Colforsin; Cyclic GMP; Cyclic N-Oxides; Cystic Fibrosis; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Free Radical Scavengers; Guanylate Cyclase; Humans; Imidazoles; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Purinones; Quinoxalines; Young Adult | 2012 |
Reduction of cAMP and cGMP inhibitory effects in human platelets by MRP4-mediated transport.
Topics: Biological Transport, Active; Blood Platelets; Cell Adhesion Molecules; Colforsin; Cyclic AMP; Cyclic GMP; Cytoplasmic Granules; Humans; Microfilament Proteins; Multidrug Resistance-Associated Proteins; Nitroprusside; Phosphoproteins; Phosphorylation; Platelet Aggregation; Propionates; Quinolines | 2012 |
Acute effects of hexabromocyclododecane on Leydig cell cyclic nucleotide signaling and steroidogenesis in vitro.
Topics: 3-Hydroxysteroid Dehydrogenases; Androgens; Animals; Cell Cycle; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Colforsin; Culture Media, Conditioned; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Environmental Pollutants; Flame Retardants; Gene Expression; Hydrocarbons, Brominated; Leydig Cells; Male; Membrane Potential, Mitochondrial; Nucleotides; Phosphoproteins; Progesterone; Rats; Rats, Wistar; Signal Transduction | 2013 |
Vasorelaxant effect of propentofylline in isolated equine digital veins.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium; Forelimb; Horses; In Vitro Techniques; Nitroprusside; Phenylephrine; Receptors, Purinergic P1; Vasoconstriction; Vasodilation; Vasodilator Agents; Veins; Xanthines | 2013 |
Differential involvement of signaling pathways in the regulation of growth hormone release by somatostatin and growth hormone-releasing hormone in orange-spotted grouper (Epinephelus coioides).
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Gene Expression Regulation; Growth Hormone; Growth Hormone-Releasing Hormone; Guanylate Cyclase; Nitric Oxide; Nitric Oxide Synthase; Perciformes; Pituitary Gland; Primary Cell Culture; Protein Kinase C; Receptors, Somatostatin; Signal Transduction; Somatostatin; Type C Phospholipases | 2014 |
The effects of forskolin and rolipram on cAMP, cGMP and free fatty acid levels in diet induced obesity.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Diet, High-Fat; Fatty Acids, Nonesterified; Female; Lipolysis; Obesity; Random Allocation; Rats; Rats, Wistar; Rolipram; Weight Gain | 2014 |
The stimulating effects of nitric oxide on intermediate conductance Ca²⁺-activated K⁺ channels in human dermal fibroblasts through PKG pathways but not the PKA pathways.
Topics: 4-Aminopyridine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dermis; Enzyme Inhibitors; Fibroblasts; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Nitric Oxide; Oxadiazoles; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Quinoxalines; Signal Transduction; Toxins, Biological; Wound Healing | 2014 |
Effects of the essential oil of Croton zehntneri and its major components, anethole and estragole, on the rat corpora cavernosa.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Colforsin; Croton; Croton Oil; Cyclic AMP; Cyclic GMP; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Penis; Phenylephrine; Piperazines; Plant Extracts; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Tissue Culture Techniques; Urological Agents | 2014 |
Modulation of cGMP accumulation by adenosine A1 receptors at the hippocampus: influence of cGMP levels and gender.
Topics: Adenosine; Adenosine Deaminase; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Female; Hippocampus; Imidazoles; Male; Nitroprusside; Rats; Rats, Wistar; Receptor, Adenosine A1; Rolipram; Triazines; Xanthines | 2014 |
Marked cortisol production by intracrine ACTH in GIP-treated cultured adrenal cells in which the GIP receptor was exogenously introduced.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Cell Line; Colforsin; Cyclic GMP; Gastric Inhibitory Polypeptide; Humans; Hydrocortisone; Pro-Opiomelanocortin; Receptors, Gastrointestinal Hormone; RNA Interference; RNA, Messenger; RNA, Small Interfering; Steroid 17-alpha-Hydroxylase; Steroid 21-Hydroxylase; Up-Regulation | 2014 |
Pyocyanin inhibits both nitric oxide-dependent and -independent relaxation in porcine coronary arteries.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Diethylamines; Dinoprost; Female; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Pseudomonas aeruginosa; Pyocyanine; Swine; Vasodilation | 2015 |
Inhibition of PDE2A, but not PDE9A, modulates presynaptic short-term plasticity measured by paired-pulse facilitation in the CA1 region of the hippocampus.
Topics: Adenosine; Animals; CA1 Region, Hippocampal; Cadmium Chloride; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Long-Term Potentiation; Male; Morpholines; Neurons; Oxadiazoles; Presynaptic Terminals; Pyrimidines; Quinoxalines; Rats; Rats, Wistar | 2015 |
The in-vitro effects of cAMP and cGMP modulators on inter-cellular dye transfer and gene expression levels in rat cumulus cell--oocyte complexes.
Topics: Animals; Carbenoxolone; Colforsin; Coloring Agents; Connexin 43; Cumulus Cells; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Extracellular Space; Female; Gap Junctions; Gene Expression Regulation; Genetic Association Studies; Meiosis; Oocytes; Phosphodiesterase Inhibitors; Rats, Sprague-Dawley; RNA, Messenger; Time Factors | 2016 |
Characterization of Na+-K+-2Cl- Cotransporter Activity in Rabbit Lacrimal Gland Duct Cells.
Topics: Analysis of Variance; Animals; Carbachol; Carcinogens; Colforsin; Cyclic GMP; Dry Eye Syndromes; Hydrogen-Ion Concentration; In Vitro Techniques; Lacrimal Apparatus; Male; Ophthalmic Solutions; Osmolar Concentration; Rabbits; Solute Carrier Family 12, Member 2; Tears; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 2016 |
Phosphodiesterase 3A expression and activity in the murine vasculature is influenced by NO-sensitive guanylyl cyclase.
Topics: Animals; Aorta; Blood Platelets; Blood Pressure; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Down-Regulation; Guanylate Cyclase; Mice; Mice, Inbred C57BL; Mice, Knockout; Milrinone; Muscle Relaxation; Myocytes, Smooth Muscle; Nitric Oxide; Signal Transduction | 2018 |
cAMP signaling primes lung endothelial cells to activate caspase-1 during
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Alprostadil; Animals; Caspase 1; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Endothelial Cells; Gene Expression Regulation; Host-Pathogen Interactions; Inflammasomes; Interleukin-1beta; Lung; Primary Cell Culture; Pseudomonas aeruginosa; Rats; Rolipram; Signal Transduction; Single-Cell Analysis | 2020 |