Page last updated: 2024-08-23

colforsin and clozapine

colforsin has been researched along with clozapine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.76)18.7374
1990's6 (35.29)18.2507
2000's7 (41.18)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K1
Ashby, CR; Hitzemann, R; Rubinstein, JE; Wang, RY1
Andersen, PH; Braestrup, C1
Asghari, V; Buchwaldt, S; Jovanovic, V; Paterson, A; Sanyal, S; Van Tol, HH1
Jones, SB; Liston, DR; Ward, KM; Zorn, SH1
Griffon, N; Pilon, C; Sautel, F; Schwartz, JC; Sokoloff, P1
Maullu, C; Olianas, MC; Onali, P1
Carson, MJ; Neal, MJ; Sutcliffe, JG; Thomas, EA1
Bobirnac, I; Bruinvels, AT; Danzeisen, M; Gazi, L; Geisse, S; Hoyer, D; Schoeffter, P; Schüpbach, E; Sommer, B; Tricklebank, M1
Armogida, M; Chiacchio, S; Colzi, A; Corsini, GU; DeMontis, MG; Maggio, R; Scarselli, M1
Fu, D; Javitch, JA; Lin, H; Strange, PG; Wilson, J1
Basta-Kaim, A; Budziszewska, B; Jaworska-Feil, L; Kubera, M; Lasoń, W; Leśkiewicz, M; Tetich, M1
Saifullah, AS; Tomioka, K1
Akam, E; Strange, PG1
Andressen, KW; Krobert, KA; Levy, FO1
Klein, MT; Teitler, M1

Other Studies

17 other study(ies) available for colforsin and clozapine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship

2010
One year treatment with haloperidol or clozapine fails to alter neostriatal D1- and D2-dopamine receptor sensitivity in the rat.
    Brain research, 1989, Jul-24, Volume: 493, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Benzazepines; Clozapine; Colforsin; Corpus Striatum; Cyclic AMP; Dibenzazepines; Drug Synergism; Ergolines; Haloperidol; Male; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2

1989
Evidence for different states of the dopamine D1 receptor: clozapine and fluperlapine may preferentially label an adenylate cyclase-coupled state of the D1 receptor.
    Journal of neurochemistry, 1986, Volume: 47, Issue:6

    Topics: Adenylyl Cyclases; Animals; Benzazepines; Binding Sites; Clozapine; Colforsin; Corpus Striatum; Dibenzazepines; Dopamine; Humans; Kinetics; Phospholipases A; Phospholipases A2; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Synaptic Membranes

1986
Modulation of intracellular cyclic AMP levels by different human dopamine D4 receptor variants.
    Journal of neurochemistry, 1995, Volume: 65, Issue:3

    Topics: Animals; Benzamides; Cell Line; CHO Cells; Clozapine; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Dopamine; Haloperidol; HeLa Cells; Humans; Raclopride; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D4; Recombinant Proteins; Salicylamides; Spiperone; Transfection

1995
Clozapine is a potent and selective muscarinic M4 receptor agonist.
    European journal of pharmacology, 1994, Nov-15, Volume: 269, Issue:3

    Topics: Animals; Carbachol; CHO Cells; Clozapine; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Humans; Hydrolysis; Muscarinic Agonists; N-Methylscopolamine; Parasympatholytics; Phosphatidylinositols; Salivation; Scopolamine Derivatives

1994
Antipsychotics with inverse agonist activity at the dopamine D3 receptor.
    Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:10

    Topics: Animals; Antipsychotic Agents; Calcium; CHO Cells; Clozapine; Colforsin; Cricetinae; Cyclic AMP; DNA Replication; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Flupenthixol; Glioma; Haloperidol; Humans; Hybrid Cells; Naphthalenes; Neuroblastoma; Pertussis Toxin; Phenothiazines; Pimozide; Pyrrolidines; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D3; Recombinant Proteins; Risperidone; Salicylamides; Second Messenger Systems; Sulpiride; Tetrahydronaphthalenes; Tumor Cells, Cultured; Virulence Factors, Bordetella

1996
Effects of clozapine on rat striatal muscarinic receptors coupled to inhibition of adenylyl cyclase activity and on the human cloned m4 receptor.
    British journal of pharmacology, 1997, Volume: 122, Issue:3

    Topics: Adenylyl Cyclases; Alkylation; Animals; Cell Membrane; CHO Cells; Clozapine; Colforsin; Corpus Striatum; Cricetinae; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Male; Muscarinic Antagonists; N-Methylscopolamine; Protein Binding; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Synaptosomes

1997
Unique allosteric regulation of 5-hydroxytryptamine receptor-mediated signal transduction by oleamide.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Dec-09, Volume: 94, Issue:25

    Topics: Allosteric Regulation; Allosteric Site; Animals; Cats; Cell Line; Cerebrosides; Clozapine; Colforsin; Cyclic AMP; GTP-Binding Proteins; HeLa Cells; Humans; Isoproterenol; Oleic Acids; Phosphatidylinositols; Rats; Receptors, Serotonin; Serotonin; Signal Transduction

1997
The agonist activities of the putative antipsychotic agents, L-745,870 and U-101958 in HEK293 cells expressing the human dopamine D4.4 receptor.
    British journal of pharmacology, 1998, Volume: 124, Issue:5

    Topics: Aminopyridines; Antipsychotic Agents; Cell Line; Clozapine; Colforsin; Cyclic AMP; Dopamine; Dopamine Agonists; Dopamine Antagonists; Humans; Kidney; Piperidines; Pyridines; Pyrroles; Raclopride; Receptors, Dopamine D2; Receptors, Dopamine D4; Recombinant Proteins; Salicylamides; Spiperone

1998
Reconstitution of functional dopamine D(2s) receptor by co-expression of amino- and carboxyl-terminal receptor fragments.
    European journal of pharmacology, 2000, Jun-02, Volume: 397, Issue:2-3

    Topics: Animals; Apomorphine; Binding, Competitive; Clozapine; Colforsin; COS Cells; Cyclic AMP; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Gene Expression; Haloperidol; Membranes; Peptide Fragments; Pergolide; Quinpirole; Radioligand Assay; Rats; Receptors, Dopamine D2; Recombinant Fusion Proteins; Spiperone; Transfection; Tritium

2000
Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation.
    Journal of neurochemistry, 2001, Volume: 77, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Binding, Competitive; Bromocriptine; Butaclamol; Chlorpromazine; CHO Cells; Clozapine; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; GTP-Binding Proteins; Haloperidol; Humans; Macromolecular Substances; Mutagenesis, Site-Directed; Phenethylamines; Piperidines; Protein Binding; Protein Conformation; Radioligand Assay; Receptors, Dopamine D2; Recombinant Fusion Proteins; Sodium; Spiperone; Structure-Activity Relationship; Sulpiride; Transfection; Tyramine

2001
Chlorpromazine inhibits the glucocorticoid receptor-mediated gene transcription in a calcium-dependent manner.
    Neuropharmacology, 2002, Volume: 43, Issue:6

    Topics: Animals; Antipsychotic Agents; Calcimycin; Calcium; Calcium Channel Blockers; Cell Line; Cell Line, Transformed; Chloramphenicol O-Acetyltransferase; Chlorpromazine; Clozapine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrenes; Fibroblasts; Gene Expression Regulation; Genes, Reporter; Haloperidol; Histamine; Histamine H1 Antagonists; Ionophores; Mammary Tumor Virus, Mouse; Mice; Nifedipine; Phorbol Esters; Phosphodiesterase Inhibitors; Protein Kinase C; Protein Kinase C-alpha; Pyrilamine; Pyrrolidinones; Raclopride; Receptors, Glucocorticoid; Remoxipride; Sulfonamides; Sulpiride; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription, Genetic; Type C Phospholipases

2002
5-HT(7)-like receptors mediate serotonergic modulation of photo-responsiveness of the medulla bilateral neurons in the cricket, Gryllus bimaculatus.
    Zoological science, 2003, Volume: 20, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Clozapine; Colforsin; Dose-Response Relationship, Drug; Electrophysiology; Gryllidae; Ketanserin; Light; Neurons; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Visual Pathways

2003
Inverse agonist properties of atypical antipsychotic drugs.
    Biochemical pharmacology, 2004, Jun-01, Volume: 67, Issue:11

    Topics: Animals; Antipsychotic Agents; Butaclamol; CHO Cells; Clozapine; Colforsin; Cricetinae; Cyclic AMP; Drug Interactions; Female; Humans; Receptors, Dopamine D2; Risperidone; Sodium

2004
Heterologous desensitization is evoked by both agonist and antagonist stimulation of the human 5-HT(7) serotonin receptor.
    European journal of pharmacology, 2006, Feb-17, Volume: 532, Issue:1-2

    Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Cell Line; Cell Membrane; Clozapine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Ergolines; Gene Expression; Humans; Isoproterenol; Isoquinolines; Methiothepin; Multivariate Analysis; Phenols; Protein Isoforms; Protein Kinase Inhibitors; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Time Factors; Tritium

2006
Antagonist interaction with the human 5-HT(7) receptor mediates the rapid and potent inhibition of non-G-protein-stimulated adenylate cyclase activity: a novel GPCR effect.
    British journal of pharmacology, 2011, Volume: 162, Issue:8

    Topics: Adenylyl Cyclases; Clozapine; Colforsin; Cyclic AMP; HEK293 Cells; Humans; Receptors, G-Protein-Coupled; Receptors, Serotonin; Serotonin Antagonists

2011