colforsin has been researched along with alprostadil in 280 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 104 (37.14) | 18.7374 |
| 1990's | 130 (46.43) | 18.2507 |
| 2000's | 36 (12.86) | 29.6817 |
| 2010's | 9 (3.21) | 24.3611 |
| 2020's | 1 (0.36) | 2.80 |
| Authors | Studies |
|---|---|
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Kamei, C; Mukai, T; Tasaka, K | 1 |
| Middleton, B | 1 |
| Birnbaumer, L; Birnbaumer, M; Gudermann, T | 1 |
| Mader, SL | 1 |
| Heemskerk, JW; Sage, SO | 1 |
| González-Utor, AL; Hidalgo, J; Sánchez-Aguayo, I | 1 |
| Elzinga, L; Grant, M; Grantham, JJ; Sharma, M; Swan, S; Torres, VE; Ye, M | 1 |
| Hersh, LB | 1 |
| Bode, AP; Norris, HT | 1 |
| Gnegy, ME; Mangels, LA | 1 |
| Lerer, B; Lichtenberg, P; Newman, ME; Shapira, B | 1 |
| Berry-Kravis, E; Huttenlocher, PR | 1 |
| Hayashi, Y; Honda, A; Ichikawa, A; Namba, T; Narumiya, S; Negishi, M; Sugimoto, Y | 1 |
| Bockman, RS; Guidon, PT; Rapuano, BE; Salvatori, R | 1 |
| Cooper, DM; Yoshimura, M | 1 |
| Camden, JM; Turner, JT | 1 |
| Jakobs, KH; Ronzani, M; Wieland, T | 1 |
| Duff, HJ; Hill, RJ; Sheldon, RS; Taouis, M | 1 |
| Downs, TR; Frohman, LA | 1 |
| Jackson, MB; Shao, XM; Yakel, JL | 1 |
| Brodde, OE; Maisel, AS; Michel, MC; Motulsky, HJ; van Tits, LJ | 1 |
| Simmons, NL | 1 |
| Bloom, JW; Lai, J; Roeske, WR; Waite, SL; Yamamura, HI | 1 |
| Scarpa, A; Wiener, E | 2 |
| Fromm, M; Hegel, U; Kreusel, KM; Schulzke, JD | 1 |
| McCook, EC; Nemeroff, CB; Seidler, FJ; Slotkin, TA | 1 |
| Brain, CE; Chomczynski, P; Downs, TR; Frohman, LA | 1 |
| Bleasdale, JE; Denlinger, LC; Fisher, SK; Mostafapour, SP; Thompson, AK | 1 |
| Brodde, OE; Klüppel, M; Michel, MC; Philipp, T | 1 |
| Lovenberg, TW; Mailman, RB; Nestler, EJ; Nichols, DE; Roth, RH | 1 |
| Boege, F; Cantrill, RC; Hahn, M; Heithier, H; Kurstjens, NP | 1 |
| Bali, JP; Choquet, A; Leonard, A; Magous, R | 1 |
| Iwashita, S; Mitsui, K; Senshu-Miyaike, M; Shoji-Kasai, Y | 1 |
| Duan, DS; Eiger, S; Lameh, J; Sadée, W; Yu, VC | 1 |
| Harvath, L; Robbins, JD; Russell, AA; Seamon, KB | 1 |
| Hoffmann, A; Klöcking, HP | 1 |
| Nakagawa-Yagi, Y; Saito, Y; Takada, Y; Takayama, M | 1 |
| Lübbecke, F; Matthias, FR; Wizemann, V | 1 |
| Brown, CD; Simmons, NL | 1 |
| Connell, JM; Houslay, MD; Livingstone, C; McGregor, MA; McLellan, AR; Milligan, G; Paterson, KR; Small, M; Wilson, A | 1 |
| Birnbaumer, M; Clark, RB; Friedman, J; Halligan, RD; Johnson, JA | 1 |
| Jackson, CA; Peterson, JW; Reitmeyer, JC | 1 |
| Abemayor, E; Lando, M; Sidell, N; Verity, MA | 1 |
| Laurenza, A; Morris, D; Seamon, KB | 1 |
| Convents, A; De Baetselier, P; De Vos, H; Vauquelin, G; Verschueren, H | 1 |
| Drolet, DW; Fendly, BM; Gibson, UE; Johnston, PD; Kramer, SM; Mohler, MA | 1 |
| Birnbaumer, L; Birnbaumer, M; Liao, CF; Schilling, WP | 1 |
| Hui, KK; Yu, JL | 2 |
| el Hessni, A; Graulet, AM; Gueris, J; Loiseau, A; Silve, C; Suarez, F | 1 |
| Patke, CL; Shearer, WT | 1 |
| Aiyar, N; Crooke, ST; Nambi, P | 1 |
| Hornsby, PJ; Naseeruddin, SA | 1 |
| Deguchi, K; Nishikawa, M; Saitoh, M; Shirakawa, S | 1 |
| Novak, TJ; Rothenberg, EV | 1 |
| McArdle, CA | 1 |
| Cochaux, P; Dumont, JE; Van Sande, J | 2 |
| de Chaffoy de Courcelles, D; Roevens, P; van Belle, H | 2 |
| Ishitoya, J; Takenawa, T | 1 |
| Barker, S; Cassity, N; Martinez, JR | 1 |
| Haslam, RJ; Murphy, W; Williams, KA | 1 |
| Berry-Kravis, E; Dawson, G; Derechin, V; Kazmierczak, BI | 1 |
| Emoto, T; Hiraiwa, M; Kasai, K; Shimoda, S | 1 |
| Hu, JS; Olson, EN | 1 |
| Evan, GI; Mehmet, H; Moore, JP; Rozengurt, E; Sinnett-Smith, J | 1 |
| Dawson, G; McAtee, P | 1 |
| Grantham, JJ; Lechene, C; Mangoo-Karim, R; Uchic, M | 1 |
| Akil, M; Fisher, SK | 1 |
| Calvet, JP; Grant, M; Grantham, JJ; Mangoo-Karim, R; Park, CH; Shumate, WA; Uchic, ME | 2 |
| Müller, B; Schmidtke, M; Witt, W | 1 |
| Gaur, A; Phipps, RP; Quill, H | 1 |
| Milligan, G; Mullaney, I | 1 |
| Ball, SG; Balmforth, AJ; Vaughan, PF; Yasunari, K | 1 |
| Clark, RB; Friedman, J; Kunkel, MW; Shenolikar, S | 1 |
| Barber, R; Butcher, RW; Goka, TJ | 1 |
| Hasegawa, T; Koshiura, R; Matsunaga, T; Miyamoto, K; Sanae, F; Satake, T; Takagi, K | 1 |
| Byczko, Z; Murphy, MG | 1 |
| Kaiya, H; Nozaki, M; Ofuji, M; Tsurumi, K | 1 |
| Houslay, MD; Spence, S | 1 |
| Brodde, OE; Michel, MC | 1 |
| Ebstein, RP; Greenberg, D; Lerer, B; Shemesh, Z; Shestatsky, M | 1 |
| Dan'ura, T; Ishibashi, S; Kurokawa, T; Yamashita, A; Yanagiuchi, H | 1 |
| Adams, M; Boarder, MR; Marriott, D | 1 |
| Abita, JP; Calvo, F; Cost, H; de Cremoux, P; Gauville, C; Lagier, G; Lechat, P | 1 |
| Sadée, W; Yu, VC | 1 |
| Cole, JA; Eber, S; Forte, LR; Poelling, RE; Thorne, PK | 1 |
| Gregerman, RI; Kirkland, JL; Li, ZH; Lu, ZD; Piñeyro, MA | 1 |
| Coughlin, SR; Kacich, RL; Williams, LT | 1 |
| Crooke, ST; Stadel, JM | 1 |
| Reithmann, C; Werdan, K | 1 |
| Hashida, T; Imashuku, S; Todo, S | 1 |
| Enloe, L; Forray, C; Pfenning, M; Richelson, E; Stenstrom, S | 1 |
| Akamizu, T; Imura, H; Iwamori, M; Kosugi, S; Miyamoto, M; Mori, T; Nagai, Y; Sugawa, H | 1 |
| Bühler, FR; Dimitrov, D; Resink, TJ; Stucki, S | 1 |
| Anand-Srivastava, MB; Cantin, M; Genest, J | 1 |
| Evans, T; Harden, TK; Hepler, JR; Hughes, AR; Martin, MW; Meeker, RB; Smith, MM; Tanner, LI | 1 |
| Heldin, NE; Karlsson, FA; Westermark, B | 1 |
| Fatemi, SH | 1 |
| Ebstein, RP; Goldin, LR; Lipschitz, Y; Mintzer, J; Shemesh, Z; Stessmann, J | 1 |
| Cantin, M; De Léan, A; Kuchel, O; Racz, K | 1 |
| Adelman, B; Bertelé, V; Fuhro, R; Salzman, E; Schafer, A; Smith, M; Stemerman, M | 1 |
| Kariya, T; Morito, F; Sakai, T; Takahata, K; Yamanaka, M | 1 |
| Colucci, WS | 1 |
| Jakobs, KH; Watanabe, Y | 2 |
| Cronin, MJ; Summers, ST | 1 |
| Goto, H; Kato, R; Uzumaki, H; Yamamoto, S | 1 |
| Hoult, JR; Nourshargh, S | 1 |
| Ebstein, RP; Lipschitz, Y; Mintzer, J; Shemesh, Z; Stessman, J | 1 |
| Diamond, J; Vegesna, RV | 2 |
| Anand-Srivastava, MB; Cantin, M | 1 |
| Kimura, A; Nakagawa, H; Ohuchi, T; Oka, M | 1 |
| Fukuda, T; Kamikawa, Y; Makino, S; Yukawa, T | 1 |
| Clark, RB; Goka, TJ; Johnson, JA | 1 |
| Condorelli, M; Marone, G; Triggiani, M; Vigorita, S | 1 |
| Aldern, KA; Harris, SE; Hornsby, PJ | 1 |
| Glomset, JA; Krebs, EG; Lerea, KM | 1 |
| Decoster, C; Dumont, JE; Mockel, J; Van Sande, J | 1 |
| Ballard, PL; Dattel, BJ; Davis, DJ; Roberts, JM | 1 |
| Howlett, AC; Walz, MA | 1 |
| Grega, DS; Macdonald, RL | 1 |
| Collins, M; Murray, M; Rozengurt, E; Zachary, I | 1 |
| Bell, JD; Brunton, LL | 1 |
| Fox, JE; Johnson, MM; Reynolds, CC | 1 |
| Feldman, R; Motulsky, HJ; Smith, D; Terman, BI | 1 |
| Greiner, C; Jakobs, KH | 1 |
| Greenbaum, LM; Sugio, K | 1 |
| Jamieson, GA; Tandon, NN; Tralka, TS | 1 |
| Levitzki, A; Lowy, DR; Pastan, I; Rudick, J; Vass, WC | 1 |
| Ramkumar, V; Stiles, GL | 1 |
| Cavallo, G; Franco, A; Gariglio, M; Landolfo, S | 1 |
| Bühler, FR; Dimitrov, DP | 1 |
| Nelson, CA; Seamon, KB | 2 |
| Cho, YH; Housman, A; Weiss, RM; Wheeler, MA | 1 |
| Griffin, MT; Law, PY; Loh, HH | 1 |
| Higashida, H; Kato, K; Sano, M | 1 |
| Bauer, S; Jakobs, KH; Watanabe, Y | 1 |
| Bauer, S; Horn, F; Jakobs, KH; Watanabe, Y | 1 |
| Cooke, BA; Dix, CJ; Habberfield, AD | 1 |
| Cantin, M; De Léan, A; Genest, J; Gutkowska, J; Nguyen, TT; Racz, K | 1 |
| Cochaux, P; Decoster, C; Delbeke, D; Dumont, JE; Van Sande, J | 1 |
| Cronin, MJ; Hewlett, EL; MacLeod, RM; Myers, GA | 1 |
| Scharf, RE; Schneider, W; Tsamaloukas, A | 1 |
| Egan, JJ; Feinstein, MB; Sha'afi, RI; White, J | 1 |
| de Vellis, J; Wu, DK | 1 |
| Daly, JW; Sugio, K | 2 |
| Barovsky, K; Brooker, G; Pedone, C | 1 |
| Bokoch, GM; Gilman, AG; Katada, T; Northup, JK; Ui, M | 1 |
| Field, JB; Nielsen, TB; Totsuka, Y | 1 |
| McMahon, KK; Schimmel, RJ | 1 |
| Agarwal, KC; Parks, RE | 1 |
| Ferry, N; Hanoune, J; Insel, PA; Stengel, D | 1 |
| Grimminger, F; Hansen, T; Krämer, HJ; Rössig, R; Schmehl, T; Schütte, H; Seeger, W; Suttorp, N; Walmrath, D; Weissmann, N | 1 |
| Butryn, RK; Frank, RN; Hull, CM; Ruan, H | 1 |
| Casolaro, V; de Paulis, A; Guidi, G; Marino, O; Marone, G; Meliota, S; Patella, V | 1 |
| Dean, T; Kornhauser, R | 1 |
| Ko, FN; Kuo, SC; Lee, FY; Teng, CM; Wu, CC | 1 |
| Kawahara, Y; Koide, M; Nakayama, I; Tsuda, T; Yokoyama, M | 1 |
| Bönisch, D; Grosser, T; Schrör, K; Zucker, TP | 1 |
| Maggi, R; Martini, L; Pimpinelli, F; Piva, F | 1 |
| al Haq, A; Benzakour, O; Berg, LP; Cooper, DN; Dennehy, U; Kakkar, VV; Kanthou, C | 1 |
| Barrett, KE | 1 |
| Bloom, SR; Rozengurt, E; Withers, DJ | 1 |
| Collin, JP; Pontoire, C; Van Camp, G; Voisin, P | 1 |
| Elias, JA; Zheng, T; Zitnik, RJ | 1 |
| Archipoff, G; Bartha, K; Beretz, A; Brisson, C; Cazenave, JP; de la Salle, C; Froget-Léon, C; Klein-Soyer, C | 1 |
| Anderson, GM; Arora, RC; Berry-Kravis, EM; Charak, DA; Cook, EH; Leventhal, BL; Sklena, PJ; Yan, SY; Yeoh, HC | 1 |
| Herman, P; Marianowski, R; Martin, F; Tran Ba Huy, P; Tu, TY | 1 |
| Hönig-Liedl, P; Horstrup, K; Jablonka, B; Just, M; Kochsiek, K; Walter, U | 1 |
| al-Essa, L; Kohno, K; Niwa, M; Tsurumi, K | 1 |
| Houslay, MD; Livingstone, C; MacDonald, C; Willett, B | 1 |
| Christ, GJ; Giraldi, A; Melman, A; Palmer, LS; Valcic, M; Wagner, G | 1 |
| Goldstein, JL; Layden, TJ; Rao, MC; Sahi, J | 1 |
| Anand-Srivastava, MB | 1 |
| Harazono, A; Honda, A; Ichikawa, A; Irie, A; Namba, T; Narumiya, S; Negishi, M; Sugimoto, Y; Watabe, A | 1 |
| Hoffman, JM; Kreps, DM; Toews, ML; Whittle, SM | 1 |
| Clark, CJ; Connell, JM; Milligan, G | 1 |
| Adie, EJ; Kim, GD; Milligan, G | 1 |
| Ikeda, K; Inoue, D; Matsumoto, T; Ogata, E; Okazaki, R | 1 |
| Clark, RB; Friedman, J; January, BG; Kunkel, MW; Shenolikar, S | 1 |
| Härmälä, AS; Jansson, C; Slotte, JP; Toivola, DM | 1 |
| Metakis, L; Notterman, DA; Singh, M | 1 |
| Butcher, RW; Clark, RB; Proll, MA | 1 |
| Nash, MS; Osborne, NN | 1 |
| Chilvers, ER; Cousin, JM; Dransfield, I; Haslett, C; Lawson, MF; Rossi, AG | 1 |
| Alvarez, R; Kaneko, T; Nadel, JA; Ueki, IF | 1 |
| Pantuck, CB; Smiley, RM | 1 |
| Hoffman, BB; Thomas, JM | 1 |
| Cahn, D; Christ, GJ; Melman, A; Valcic, M | 1 |
| Benya, PD; Fu, YH; Hahn, TJ; Lowe, GN; McDougall, S; Polendo, R; Williams, A | 1 |
| Ashikaga, T; Kishi, Y; Numano, F | 1 |
| Hartle, JE; Prpic, V; Quarles, LD; Siddhanti, SR; Spurney, RF | 1 |
| Goldstein, I; Moreland, RB; Palmer, MS; Traish, AM | 1 |
| MacLeod, KM; Zhang, JZ | 1 |
| Fujiwara, Y; Inada, M; Kaji, T; Koizumi, F; Yamamoto, C | 1 |
| Benzakour, O; Kakkar, VV; Kanse, SM; Kanthou, C | 1 |
| Hazeki, K; Hazeki, O; Katada, T; Suzuki, T; Ui, M | 1 |
| Baker, I; Kulaga, H; Masserano, JM; Natsukari, N; Wyatt, RJ | 2 |
| An, S; Goetzl, EJ; Zeng, L | 1 |
| Kobayashi, Y; Otsuka, M; Saito, Y; Sato, F; Takagi, J; Wang, XQ | 1 |
| Krause, G; Kumar, R; Meyers, A; Prasad, KN | 1 |
| Advenier, C; Dumas, JP; Dumas, M; Giudicelli, JF; Rochette, L | 1 |
| Angelini, GD; Birkett, SD; Bryan, AJ; Jeremy, JY | 1 |
| Kozawa, O; Oiso, Y; Suzuki, A; Watanabe-Tomita, Y | 1 |
| Bockman, RS; Rapuano, BE; Suzuki, K | 1 |
| Ammer, H; Schulz, R | 2 |
| Daller, M; Goldstein, I; Gupta, S; Krane, RJ; Mulhall, JP; Park, K; Payton, TR; Salimpour, P; Traish, AM | 1 |
| Hänecke, K; Neuschäfer-Rube, F; Püschel, GP | 1 |
| Furuke, K; Honda, Y; Ohira, A; Sato, N; Tajima, H; Yamamoto, M; Yodoi, J | 1 |
| Gallant, C; Goldstein, I; Huang, YH; Moreland, RB; Traish, AM | 1 |
| Harada, A; Isobe, KI; Kozawa, O; Tokuda, H; Uematsu, T | 1 |
| Schulz, R; Wehmeyer, A | 1 |
| Middleton, A; Middleton, B | 1 |
| Hohlfeld, T; Schrör, K | 1 |
| Kaida, T; Kozawa, O; Matsuno, H; Tokuda, H; Uematsu, T | 2 |
| Kozawa, O; Matsuno, H; Tokuda, H; Uematsu, T | 1 |
| Goldstein, JL; Layden, TJ; Moyer, MP; Nataraja, SG; Rao, MC; Sahi, J | 1 |
| Choung, J; Kagan, H; Polgar, P; Taylor, L; Thomas, K; Yang, X; Zhou, X | 1 |
| Bruzzese, N; Cittadini, A; Corda, D; Covacci, V; Di Francesco, A; Sacchetti, A; Wolf, FI | 1 |
| Hill, J; Howlett, A; Klein, C; McVey, M | 1 |
| Kozawa, O; Shinoda, J; Tokuda, H; Uematsu, T | 1 |
| Goto, M; Ichikawa, A; Ishibashi, R; Kotani, M; Mukoyama, M; Muro, S; Nakao, K; Narumiya, S; Sugawara, A; Sugimoto, Y; Tanaka, I | 1 |
| Berman, J; Goldstein, I; Huang, YH; Kim, NN; Moreland, RB; Traish, A | 1 |
| Chang, SH; Lin, WW; Wang, SM | 1 |
| Hohlfeld, T; Meyer-Kirchrath, J; Schrör, K; Vogel, YC | 1 |
| Marfella-Scivittaro, C; Orellana, SA | 1 |
| Goldstein, I; Huang, YH; Kim, NN; Moreland, RB; Traish, A | 1 |
| Albert, DM; Dutkiewicz, R; Levin, LA | 1 |
| Kotani, M; Matsumoto, T; Muro, S; Nakao, K; Narumiya, S; Ogawa, Y; Sagawa, N; Suganami, T; Sugawara, A; Tanaka, I; Yamamoto, Y; Yoshimasa, Y | 1 |
| Endo, H; Ishikawa, I; Iwasaki, K; Kondo, H; Noguchi, K; Shitashige, M | 1 |
| Aizawa, Y; Fuse, I; Higuchi, W | 1 |
| Blanqué, R; Cottereaux, C; Gardner, CR | 1 |
| Andelfinger, G; Bouayad, A; Chemtob, S; Clyman, RI; Fouron, JC; Gobeil, F; Kajino, H; Skoll, A; Varma, DR; Vazquez, A; Waleh, N | 1 |
| Kao, C; Rowlands, DK; Wise, H | 1 |
| Hatakeyama, D; Kato, K; Kozawa, O; Matsuno, H; Niwa, M; Shibata, T; Tatematsu, N; Uematsu, T | 1 |
| Cicha, MZ; Kopp, UC; Smith, LA | 1 |
| Baas, MJ; Cazenave, JP; Cranmer, SL; Jackson, SP; Lanza, F; Mangin, P; Moog, S; Perrault, C; Pikovski, I; Santer, M; Williamson, D | 1 |
| Chakrabarti, S; Chakraborty, C; Lala, PK; Timoshenko, AV; Xu, G | 1 |
| Fischer, JW; Meyer-Kirchrath, J; Nüsing, RM; Sarbia, M; Schrör, K; Sussmann, M | 1 |
| Cindrova-Davies, T; Li, RC; Sellers, LA; Skepper, JN | 1 |
| Itoh, M; Kakita, A; Miura, Y; Oiso, Y; Ono, Y; Suzuki, A | 1 |
| Ganea, D; Jing, H; Sheibanie, AF; Tadmori, I; Vassiliou, E | 1 |
| Ishisaki, A; Kanno, Y; Kozawa, O; Nakajima, K; Numata, O; Shibata, T; Tokuda, H | 1 |
| Chemtob, S; Clyman, RI; Fouron, JC; Ginzinger, D; Kajino, H; Marrache, AM; Moss, TJ; Roman, C; Seidner, SR; Vazquez-Tello, A; Waleh, N | 1 |
| Bretschneider, E; Censarek, P; Fischer, JW; Meyer-Kirchrath, J; Pape, R; Rabausch, K; Sarbia, M; Schrör, K; Weber, AA | 1 |
| Altman, Y; Yaron, A; Zadik, Z; Zung, A | 1 |
| Chernikhova, TV; Hubich, AI; Koroleva, EV; Lakhvich, FA; Sholukh, MV; Zheldakova, TA | 1 |
| Cooper, DM; Willoughby, D | 1 |
| Aratsu, Z; Bouscarel, B; Ceryak, S; Epstein, L; Jones, L; Meng, JP | 1 |
| Cope, G; Cuthbert, AW; MacVinish, LJ; Ropenga, A | 1 |
| Black, SA; Palamakumbura, AH; Stan, M; Trackman, PC | 1 |
| Eguchi, S; Kawano, T; Mawatari, K; Nakajo, N; Nakaya, Y; Oshita, S; Takahashi, A; Tanaka, K; Yasui, S | 1 |
| Heinrich, PC; Müller, PJ; Schaper, F; Sobota, RM | 1 |
| Dohi, S; Kato, K; Kozawa, O; Matsushima-Nishiwaki, R; Takai, S; Tanabe, K | 1 |
| Kimura, SH; Nagano, T; Takemura, M | 1 |
| Holmsen, H; Vorland, M | 1 |
| Carrasco, E; Casper, D; Werner, P | 1 |
| Breyer, RM; Chen, C; Yang, H; Zhang, J | 1 |
| Camargo, PM; Moldovan, SM; Nervina, JM; Tetradis, S | 1 |
| Bijvelds, MJ; Bot, AG; De Jonge, HR; Escher, JC | 1 |
| Bindslev, N; Hansen, MB; Kaltoft, N; Osbak, PS; Poulsen, SS; Tilotta, MC; Witte, AB | 1 |
| Balazs, L; Kaminsky, J; Li, F; Liu, X; Ostrom, RS; Sun, SQ; Thangavel, M | 1 |
| Ao, M; Benya, RV; Boonkaewwan, C; Ganesan, N; Rao, MC; Syed, A; Venkatasubramanian, J | 1 |
| Matthiesen, K; Nielsen, J | 1 |
| Adris, P; Bogard, AS; Ostrom, RS | 1 |
| Chakrabarti, J; Cuppoletti, J; Malinowska, DH; Tewari, K | 1 |
| Bertherat, J; Cazabat, L; Guellich, A; Lechêne, P; Nikolaev, VO; Potier-Cartereau, M; Ragazzon, B; Richter, W; Risk-Rabin, M; Schittl, J; Vandecasteele, G; Vandier, C; Varin, A; Vezzosi, D; Zhang, J | 1 |
| Doré, S; Mohan, S; Narumiya, S | 1 |
| Alvarez, DF; Annamdevula, N; Audia, JP; Britain, A; Dunbar, G; Hardy, KS; Housley, N; Leavesley, S; Renema, P; Rich, T; Spadafora, D | 1 |
1 review(s) available for colforsin and alprostadil
| Article | Year |
|---|---|
The use of inhibitors of platelet activation or protease activity in platelet concentrates stored for transfusion.
Topics: Alprostadil; Blood Component Transfusion; Blood Platelets; Blood Preservation; Colforsin; Cyclic AMP; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Protease Inhibitors; Temperature; Theophylline; Thrombin | 1992 |
2 trial(s) available for colforsin and alprostadil
| Article | Year |
|---|---|
Platelet adenylate cyclase activity in depression and after clomipramine and lithium treatment: relation to serotonergic function.
Topics: Adenylyl Cyclases; Alprostadil; Blood Platelets; Cell Membrane; Clomipramine; Colforsin; Depressive Disorder; Female; GTP-Binding Proteins; Humans; Lithium; Male; Middle Aged; Serotonin; Sodium Fluoride | 1992 |
Intracavernosal forskolin: role in management of vasculogenic impotence resistant to standard 3-agent pharmacotherapy.
Topics: Alprostadil; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Humans; Impotence, Vasculogenic; Injections; Male; Papaverine; Penis; Phentolamine; Rabbits; Vasodilator Agents | 1997 |
277 other study(ies) available for colforsin and alprostadil
| Article | Year |
|---|---|
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Histamine-induced depolarization and the cyclic AMP--protein kinase A system in isolated guinea pig adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Alprostadil; Animals; Carbazoles; Colforsin; Cyclic AMP; Electrophysiology; Epididymis; Guinea Pigs; Histamine; In Vitro Techniques; Indoles; Insulin; Isoproterenol; Male; Membrane Potentials; Protein Kinase C; Protein Kinases; Pyrroles; Rats; Rats, Wistar | 1992 |
Lysosome inhibitors enhance the ability of cyclic AMP-elevating agents to induce the LDL receptor in human vascular smooth muscle cells.
Topics: Alprostadil; Ammonium Chloride; Cells, Cultured; Chloroquine; Colforsin; Cyclic AMP; Drug Synergism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lipoproteins, LDL; Lysosomes; Muscle, Smooth, Vascular; Receptors, LDL | 1992 |
Evidence for dual coupling of the murine luteinizing hormone receptor to adenylyl cyclase and phosphoinositide breakdown and Ca2+ mobilization. Studies with the cloned murine luteinizing hormone receptor expressed in L cells.
Topics: Adenylyl Cyclases; Alprostadil; Amino Acid Sequence; Animals; Calcium; Cells, Cultured; Chorionic Gonadotropin; Cloning, Molecular; Colforsin; Cyclic AMP; DNA; Fura-2; Gene Expression; Genetic Vectors; Hydrolysis; L Cells; Mice; Molecular Sequence Data; Phosphatidylinositols; Receptors, Adrenergic, beta; Receptors, Angiotensin; Receptors, LH; Receptors, Vasopressin; Second Messenger Systems; Sequence Alignment | 1992 |
Influence of animal age on the beta-adrenergic system in cultured rat aortic and mesenteric artery smooth muscle cells.
Topics: Aging; Alprostadil; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Iodocyanopindolol; Isoproterenol; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Pindolol; Propranolol; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta | 1992 |
Thromboxane receptor stimulation inhibits adenylate cyclase and reduces cyclic AMP-mediated inhibition of ADP-evoked responses in fura-2-loaded human platelets.
Topics: Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Alprostadil; Calcium; Colforsin; Cyclic AMP; Fura-2; Humans; Manganese; Platelet Activation; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2 | 1992 |
Cytochemical localization of K(+)-dependent p-nitrophenyl phosphatase and adenylate cyclase by using one-step method in human washed platelets.
Topics: 4-Nitrophenylphosphatase; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alloxan; Alprostadil; Blood Platelets; Cell Membrane; Colforsin; Histocytochemistry; Humans; Intracellular Membranes; Prostaglandin D2; Sensitivity and Specificity | 1992 |
Cyst fluid from human autosomal dominant polycystic kidneys promotes cyst formation and expansion by renal epithelial cells in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Body Fluids; Cell Division; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Dogs; Epithelial Cells; Epithelium; Growth Substances; Humans; Interleukins; Kidney; Organ Culture Techniques; Peptides; Polycystic Kidney, Autosomal Dominant | 1992 |
Induction of choline acetyltransferase in the neuroblastoma x glioma cell line NG108-15.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Bucladesine; Choline O-Acetyltransferase; Colforsin; Cyclic AMP; Enzyme Induction; Glioma; Hybridomas; Mice; Neuroblastoma; Neurons; Rats; Tumor Cells, Cultured | 1992 |
Cyclic AMP accumulation alters calmodulin localization in SK-N-SH human neuroblastoma cells.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Alprostadil; Analgesics; Brimonidine Tartrate; Bucladesine; Calcium; Calmodulin; Carbachol; Cell Line; Colforsin; Cyclic AMP; Cytosol; Edetic Acid; Egtazic Acid; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Kinetics; Neuroblastoma; Quinoxalines; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1992 |
Cyclic AMP metabolism in fragile X syndrome.
Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Alprostadil; Blood Platelets; Child; Child, Preschool; Colforsin; Cyclic AMP; Female; Fragile X Syndrome; Humans; Intellectual Disability; Learning; Male; Memory, Short-Term; Middle Aged; Second Messenger Systems | 1992 |
Cloning and expression of a cDNA for mouse prostaglandin E receptor EP3 subtype.
Topics: Alprostadil; Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; DNA; Gene Expression; Humans; Mice; Molecular Sequence Data; Prostaglandins; Prostaglandins E, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; RNA; Sequence Homology, Nucleic Acid; Thromboxanes; Transfection | 1992 |
Prostaglandin E1 inhibits collagenase gene expression in rabbit synoviocytes and human fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Cell Line; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Fibroblasts; Gene Expression; Humans; Microbial Collagenase; Promoter Regions, Genetic; Rabbits; RNA, Messenger; Synovial Membrane | 1992 |
Cloning and expression of a Ca(2+)-inhibitable adenylyl cyclase from NCB-20 cells.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Amino Acid Sequence; Animals; Base Sequence; Calcium; Cell Line; Cell Membrane; Cloning, Molecular; Colforsin; Cyclic AMP; DNA; Guanylyl Imidodiphosphate; Humans; Hybrid Cells; Kinetics; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Protein Conformation; RNA; Sequence Homology, Nucleic Acid; Transfection | 1992 |
Regulation of secretion by vasoactive intestinal peptide in isolated perfused rat submandibular glands.
Topics: Acetylcholine; Alprostadil; Animals; Chemotherapy, Cancer, Regional Perfusion; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Isoproterenol; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Saliva; Salivary Proteins and Peptides; Secretory Rate; Submandibular Gland; Substance P; Vasoactive Intestinal Peptide | 1992 |
Stimulation and inhibition of human platelet adenylylcyclase by thiophosphorylated transducin beta gamma-subunits.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Animals; Blood Platelets; Cattle; Colforsin; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Kinetics; Macromolecular Substances; Thionucleotides; Transducin | 1992 |
Cyclic AMP-dependent regulation of the number of [3H]batrachotoxinin benzoate binding sites on rat cardiac myocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Batrachotoxins; Binding Sites; Cholera Toxin; Colforsin; Cyclic AMP; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardium; Neurotoxins; Pertussis Toxin; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Inbred Strains; Sodium Channels; Virulence Factors, Bordetella | 1991 |
Evidence for a defect in growth hormone-releasing factor signal transduction in the dwarf (dw/dw) rat pituitary.
Topics: Alprostadil; Animals; Body Weight; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dwarfism, Pituitary; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Immunohistochemistry; Kinetics; Male; Pituitary Gland, Anterior; Rats; Rats, Mutant Strains; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Activation and desensitization of the 5-HT3 receptor in a rat glioma x mouse neuroblastoma hybrid cell.
Topics: Alprostadil; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Glioma; Hybrid Cells; Kinetics; Membrane Potentials; Mice; Neuroblastoma; Rats; Receptors, Serotonin; Serotonin; Time Factors | 1991 |
Cyclic AMP counteracts mitogen-induced inositol phosphate generation and increases in intracellular Ca2+ concentrations in human lymphocytes.
Topics: Adult; Alprostadil; Calcium; Catecholamines; Colforsin; Concanavalin A; Cyclic AMP; Humans; In Vitro Techniques; Inositol Phosphates; Isoproterenol; Lymphocytes; Mitogens; Phytohemagglutinins; Pokeweed Mitogens | 1991 |
Chloride secretion stimulated by prostaglandin E1 and by forskolin in a canine renal epithelial cell line.
Topics: Alprostadil; Animals; Biological Transport, Active; Cell Line; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Dogs; Epithelium; Kidney; Nitrobenzoates; Prostaglandins | 1991 |
The m2 muscarinic acetylcholine receptors are coupled to multiple signaling pathways via pertussis toxin-sensitive guanine nucleotide regulatory proteins.
Topics: Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP; Fibroblasts; GTP-Binding Proteins; Hydrolysis; Mice; Pertussis Toxin; Phosphatidylinositols; Receptors, Muscarinic; Signal Transduction; Virulence Factors, Bordetella | 1991 |
Modulation of the B cell response to T-independent antigens by prostaglandins: evidence for effector system cross-talk.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Alprostadil; Animals; Antibodies, Anti-Idiotypic; Antigens, T-Independent; B-Lymphocytes; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Immunoglobulin M; In Vitro Techniques; Mice; Mice, Nude; Phosphoric Diester Hydrolases; Prostaglandins E | 1991 |
Cl- secretion in epithelial monolayers of mucus-forming human colon cells (HT-29/B6).
Topics: Absorption; Alprostadil; Chlorides; Colforsin; Colon; Cyclic AMP; Humans; Intestinal Mucosa; Microscopy, Electron, Scanning; Mucus; Sodium; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1991 |
Species differences in alpha 2-adrenergic regulation of platelet adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adult; Alprostadil; Animals; Blood Platelets; Clonidine; Colforsin; Down-Regulation; Humans; Male; Rabbits; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Statistics as Topic; Yohimbine | 1991 |
Impaired generation of cyclic adenosine 3',5'-monophosphate in a somatomammotroph cell line derived from dwarf (dw) rat anterior pituitaries.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Bucladesine; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dwarfism; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Pituitary Gland, Anterior; Rats; Rats, Mutant Strains; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
The aminosteroid U-73122 inhibits muscarinic receptor sequestration and phosphoinositide hydrolysis in SK-N-SH neuroblastoma cells. A role for Gp in receptor compartmentation.
Topics: Alprostadil; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Estrenes; GTP-Binding Proteins; Humans; Inositol; Kinetics; Neuroblastoma; Oxotremorine; Phosphatidylinositols; Pyrrolidinones; Receptors, Muscarinic; Scopolamine; Type C Phospholipases | 1991 |
Does treatment with beta-adrenoceptor antagonists in vivo alter human adenylate cyclase responsiveness in vitro?
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Adult; Alprostadil; Blood Platelets; Cell Membrane; Colforsin; Drug Interactions; Enzyme Activation; Female; Humans; Lymphocytes; Male | 1991 |
Guanine nucleotide binding proteins and the regulation of cyclic AMP synthesis in NS20Y neuroblastoma cells: role of D1 dopamine and muscarinic receptors.
Topics: Adenylate Cyclase Toxin; Alprostadil; Animals; Carbachol; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dopamine Agents; GTP-Binding Proteins; Kinetics; Neuroblastoma; Pertussis Toxin; Phenanthridines; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Muscarinic; Virulence Factors, Bordetella | 1991 |
Multiple hormone actions: the rises in cAMP and Ca++ in MDCK-cells treated with glucagon and prostaglandin E1 are independent processes.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Calcium; Carbachol; Cell Line; Colforsin; Cyclic AMP; Dogs; Fluorescent Dyes; Glucagon; Indoles; Isoproterenol; Kidney; Kinetics; Receptors, Gastrointestinal Hormone; Receptors, Glucagon | 1990 |
Intracellular coupling of prostaglandin inhibition of acid secretion in isolated rabbit gastric parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Aminopyrine; Animals; Anti-Ulcer Agents; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP; Gastric Acid; Histamine Antagonists; Inositol Phosphates; Misoprostol; Parietal Cells, Gastric; Rabbits; Theophylline | 1990 |
cAMP-mediated modulation of signal transduction of epidermal growth factor (EGF) receptor systems in human epidermoid carcinoma A431 cells. Depression of EGF-dependent diacylglycerol production and EGF receptor phosphorylation.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Epidermal Growth Factor; ErbB Receptors; Glycerides; Humans; Kinetics; Peptide Mapping; Phosphopeptides; Phosphorylation; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Regulation of cyclic AMP by the mu-opioid receptor in human neuroblastoma SH-SY5Y cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Cell Line; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Kinetics; Morphine; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Theophylline; Vasoactive Intestinal Peptide | 1990 |
cAMP and human neutrophil chemotaxis. Elevation of cAMP differentially affects chemotactic responsiveness.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Biological Transport; Chemotaxis, Leukocyte; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Isoproterenol; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Time Factors | 1991 |
Inhibition of thrombin-induced tissue-type plasminogen activator release by agents which increase intracellular cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Colforsin; Cyclic AMP; Ear, External; In Vitro Techniques; Milrinone; Perfusion; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Solutions; Swine; Thrombin; Tissue Plasminogen Activator | 1990 |
Carbachol enhances forskolin-stimulated cyclic AMP accumulation via activation of calmodulin system in human neuroblastoma SH-SY5Y cells.
Topics: Adenosine; Alprostadil; Atropine; Calmodulin; Carbachol; Cell Line; Colforsin; Cyclic AMP; Drug Synergism; Humans; Kinetics; Naphthalenes; Neuroblastoma; Pertussis Toxin; Polycyclic Compounds; Protein Kinase C; Trifluoperazine; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1991 |
Regulation of thrombocyte adenylate cyclase activity in terminal renal failure.
Topics: Adenylyl Cyclases; Adult; Alprostadil; Blood Platelets; Colforsin; Epinephrine; Humans; Kidney Failure, Chronic; Middle Aged; Reference Values; Renal Dialysis; Uremia | 1991 |
Arginine vasopressin stimulation of chloride secretion in Madin-Darby canine renal epithelial layers.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Cell Line; Chlorides; Colforsin; Dogs; Electrophysiology; Epithelial Cells; Epithelium; Kidney | 1991 |
Altered G-protein expression and adenylate cyclase activity in platelets of non-insulin-dependent diabetic (NIDDM) male subjects.
Topics: Adenylyl Cyclases; Alprostadil; Blood Platelets; Blotting, Western; Cell Membrane; Colforsin; Diabetes Mellitus, Type 2; Enzyme Activation; Epinephrine; GTP-Binding Proteins; Humans; Male; Signal Transduction | 1991 |
Sensitization of adenylyl cyclase by P2 purinergic and M5 muscarinic receptor agonists in L cells.
Topics: Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alprostadil; Animals; Carbachol; Colforsin; Cricetinae; Down-Regulation; Drug Synergism; Kinetics; L Cells; Magnesium; Mice; Phosphatidylinositols; Protein Kinase C; Receptors, Muscarinic; Receptors, Purinergic; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella | 1991 |
Synthesis of prostaglandins in cholera toxin-treated Chinese hamster ovary cells.
Topics: Alprostadil; Animals; Cell Line; Cholera Toxin; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Kinetics; Prostaglandins; Prostaglandins F; Thromboxane B2 | 1990 |
Modulation of intracellular cyclic adenosine monophosphate levels and the differentiation response of human neuroblastoma cells.
Topics: Acetylcholinesterase; Alprostadil; Cell Differentiation; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Neuroblastoma; Norepinephrine; Theophylline; Tretinoin; Tumor Cells, Cultured | 1990 |
Irreversible loss of [3H]forskolin binding sites in human platelets by alpha-haloacetyl analogs of forskolin.
Topics: Adenylyl Cyclases; Alkylating Agents; Alprostadil; Aluminum; Aluminum Compounds; Blood Platelets; Cell Membrane; Colforsin; Cyclic AMP; Enzyme Activation; Fluorides; Fluorine; Humans; In Vitro Techniques | 1990 |
Cyclic AMP content and invasive capacity of metastatic variants of the BW-5147 murine T-cell lymphoma.
Topics: Alprostadil; Animals; Colforsin; Cyclic AMP; Lymphoma; Neoplasm Invasiveness; Neoplasm Metastasis; Pertussis Toxin; T-Lymphocytes; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Increase in cyclic AMP levels by relaxin in newborn rhesus monkey uterus cell culture.
Topics: Actins; Alprostadil; Animals; Animals, Newborn; Antibodies; Antibodies, Monoclonal; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Female; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Macaca mulatta; Recombinant Proteins; Relaxin; Uterus | 1990 |
Cellular responses to stimulation of the M5 muscarinic acetylcholine receptor as seen in murine L cells.
Topics: Adenosine Triphosphate; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Carbachol; Cholera Toxin; Cloning, Molecular; Colforsin; Cyclic AMP; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; L Cells; Mice; Pertussis Toxin; Phosphatidylinositols; Phosphorylation; Receptors, Muscarinic; Signal Transduction; Transfection; Type C Phospholipases; Virulence Factors, Bordetella | 1990 |
Protein kinase A and/or C inhibitors potentiate isoproterenol-induced cyclic AMP accumulation in intact human lymphocytes.
Topics: Alprostadil; Colforsin; Cyclic AMP; Drug Synergism; Humans; Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Lymphocytes; Phorbol Esters; Pindolol; Protein Kinase C; Protein Kinase Inhibitors | 1990 |
The resistance to parathyroid hormone of fibroblasts from some patients with type Ib pseudohypoparathyroidism is reversible with dexamethasone.
Topics: Adult; Alprostadil; Binding Sites; Colforsin; Cyclic AMP; Dexamethasone; Drug Resistance; Drug Synergism; Fibroblasts; Humans; Parathyroid Hormone; Pseudohypoparathyroidism; Skin | 1990 |
Enhancement of cyclic AMP metabolism in a B cell line by protein kinase C.
Topics: Alkaloids; Alprostadil; B-Lymphocytes; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Down-Regulation; Drug Synergism; Humans; Immunoglobulin M; In Vitro Techniques; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Desensitization of vasopressin sensitive adenylate cyclase by vasopressin and phorbol esters.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Arginine Vasopressin; Cell Line; Colforsin; Cyclic AMP; Dogs; Isoproterenol; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Receptors, Angiotensin; Receptors, Vasopressin | 1990 |
Regulation of 11 beta- and 17 alpha-hydroxylases in cultured bovine adrenocortical cells: 3', 5'-cyclic adenosine monophosphate, insulin-like growth factor-I, and activators of protein kinase C.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Alprostadil; Animals; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Induction; Insulin; Insulin-Like Growth Factor I; Male; Protein Kinase C; RNA, Messenger; Somatomedins; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Tetradecanoylphorbol Acetate | 1990 |
[Intracellular actions of antiplatelet drugs which affect cyclic AMP metabolism in platelets--their effects on Ca2+ mobilization and protein phosphorylation in human platelets].
Topics: Alprostadil; Blood Platelets; Calcium; Carbazoles; Colforsin; Cyclic AMP; Humans; Indoles; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Pyrroles; Thromboxane A2 | 1990 |
cAMP inhibits induction of interleukin 2 but not of interleukin 4 in T cells.
Topics: Alprostadil; Animals; Bucladesine; Calcimycin; Cell Line; Colforsin; Cyclic AMP; Humans; Interleukin-1; Interleukin-2; Interleukin-4; Plasmids; Promoter Regions, Genetic; Recombinant Proteins; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1990 |
Chronic regulation of ovarian oxytocin and progesterone release by prostaglandins: opposite effects in bovine granulosa and early luteal cells.
Topics: Alprostadil; Animals; Cattle; Cells, Cultured; Colforsin; Corpus Luteum; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Female; Granulosa Cells; Insulin-Like Growth Factor I; Ovary; Oxytocin; Phorbol 12,13-Dibutyrate; Progesterone | 1990 |
Further characterization of the iodide inhibitory effect on the cyclic AMP system in dog thyroid slices.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine Triphosphate; Alprostadil; Animals; Calcium; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; Dogs; Iodides; Iodine Radioisotopes; Methimazole; Prostaglandins E; Protein Biosynthesis; RNA; Thyroid Gland; Thyrotropin; Triiodothyronine | 1985 |
Agents that elevate platelet cAMP stimulate the formation of phosphatidylinositol 4-phosphate in intact human platelets.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Blood Platelets; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Phosphatidylinositol Phosphates; Phosphatidylinositols | 1986 |
Potentiation of PGE1-induced increase in cyclic AMP by chemotactic peptide and Ca2+ ionophore through calmodulin-dependent processes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alprostadil; Animals; Calcimycin; Calmodulin; Colforsin; Cyclic AMP; Drug Synergism; Female; Guanosine Triphosphate; Guinea Pigs; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandin Antagonists; Sulfonamides; Tetradecanoylphorbol Acetate | 1987 |
Differential effects of prostaglandins and isoproterenol on cAMP content and Na, K pump activity in rat submandibular acini.
Topics: Alprostadil; Animals; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Ion Channels; Isoproterenol; Male; Ouabain; Potassium; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains; Rubidium Radioisotopes; Sodium; Submandibular Gland | 1987 |
Effects of activation of protein kinase C on the agonist-induced stimulation and inhibition of cyclic AMP formation in intact human platelets.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Alprostadil; Blood Platelets; Colforsin; Cyclic AMP; Diglycerides; Enzyme Activation; Epinephrine; Humans; Prostaglandin D2; Prostaglandins D; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
Neuromodulator-mediated phosphorylation of specific proteins in a neurotumor hybrid cell line (NCB-20).
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Alprostadil; Animals; Brain; Calcimycin; Colforsin; Cricetinae; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Embryo, Mammalian; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hybrid Cells; Immunoassay; Mice; Nerve Tissue Proteins; Neuroblastoma; Neurotransmitter Agents; Phosphoproteins; Phosphorylation; Protein Kinases; Serotonin; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1988 |
Phorbol esters modulate cyclic AMP accumulation in porcine thyroid cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1988 |
Regulation of differentiation of the BC3H1 muscle cell line through cAMP-dependent and -independent pathways.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Bucladesine; Cell Differentiation; Cell Line; Colforsin; Creatine Kinase; Cyclic AMP; Fibroblast Growth Factors; Kinetics; Mice; Muscles; Ornithine Decarboxylase; Proto-Oncogenes; Receptors, Cholinergic; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factors; Troponin; Troponin T | 1988 |
Differential induction of c-fos and c-myc by cyclic AMP in Swiss 3T3 cells: significance for the mitogenic response.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Bombesin; Cell Division; Colforsin; Cyclic AMP; DNA Replication; Fibroblasts; Gene Expression Regulation; Insulin; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Signal Transduction | 1988 |
Rapid dephosphorylation of protein kinase C substrates by protein kinase A activators results from inhibition of diacylglycerol release.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Biological Transport; Bradykinin; Brain; Bucladesine; Colforsin; Cricetinae; Diglycerides; Enzyme Activation; Glycerides; Hybrid Cells; Inositol Phosphates; Kinetics; Mice; Molecular Weight; Neuroblastoma; Phosphates; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Renal epithelial cyst formation and enlargement in vitro: dependence on cAMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Arginine Vasopressin; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Isoproterenol; Kidney; Kidney Diseases, Cystic; Terbutaline | 1989 |
Muscarinic receptor-stimulated phosphoinositide turnover in human SK-N-SH neuroblastoma cells: differential inhibition by agents that elevate cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alprostadil; Bucladesine; Carbachol; Cholera Toxin; Colforsin; Cyclic AMP; Humans; Intracellular Membranes; Ligands; Neuroblastoma; Phosphatidylinositols; Receptors, Muscarinic; Theophylline; Tumor Cells, Cultured | 1989 |
Renal epithelial fluid secretion and cyst growth: the role of cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Body Fluids; Cell Line; Colforsin; Cyclic AMP; Dogs; Epithelium; Humans; Kidney; Kidney Diseases, Cystic; Rats | 1989 |
Adherence of leucocytes to electrically damaged venules in vivo. Effects of iloprost, PGE1, indomethacin, forskolin, BW 755 C, sulotroban, hirudin, and thrombocytopenia.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Alprostadil; Animals; Cell Adhesion; Colforsin; Electric Stimulation; Epoprostenol; Hirudins; Iloprost; Indomethacin; Leukocytes; Male; Mesenteric Veins; Rats; Rats, Inbred Strains; Sulfonamides; Thrombocytopenia; Venules | 1988 |
Prostaglandin E2-dependent induction of granulocyte-macrophage colony-stimulating factor secretion by cloned murine helper T cells.
Topics: Alprostadil; Animals; Cholera Toxin; Clone Cells; Colforsin; Colony-Stimulating Factors; Dinoprost; Dinoprostone; Drug Synergism; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Interleukin-2; Kinetics; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; T-Lymphocytes, Helper-Inducer | 1989 |
Elevated levels of the guanine nucleotide binding protein, Go, are associated with differentiation of neuroblastoma x glioma hybrid cells.
Topics: Adenosine Diphosphate Ribose; Alprostadil; Blotting, Western; Bucladesine; Cell Differentiation; Cell Membrane; Colforsin; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Glioma; GTP-Binding Proteins; Hybrid Cells; Molecular Weight; NAD; Neuroblastoma; Pertussis Toxin; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1989 |
Activation of protein kinase C modulates the adenylate cyclase effector system of B-lymphocytes.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Colforsin; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Immunoglobulin M; Mice; Mice, Nude; Protein Kinase C; Spleen; Tetradecanoylphorbol Acetate | 1989 |
Glucocorticoids modify differentially dopamine- and prostaglandin E1-mediated cyclic AMP formation by the cultured human astrocytoma clone D384.
Topics: Adenylyl Cyclases; Alprostadil; Astrocytoma; Colforsin; Cyclic AMP; Cycloheximide; Dexamethasone; Dopamine; Glucocorticoids; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Kinetics; Protein Biosynthesis; Tumor Cells, Cultured | 1989 |
Cell-free heterologous desensitization of adenylyl cyclase in S49 lymphoma cell membranes mediated by cAMP-dependent protein kinase.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Alprostadil; Cell Line; Cell Membrane; Cell-Free System; Colforsin; Enzyme Activation; Epinephrine; In Vitro Techniques; Lymphoma; Protein Kinases; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1989 |
Growth of S49 cells in low concentrations of beta-adrenergic agonists causes desensitization.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Alprostadil; Animals; Colforsin; Cyclic AMP; Epinephrine; Mice; Protein Kinases; Receptors, Adrenergic, beta; Terbutaline; Time Factors; Tumor Cells, Cultured | 1989 |
Forskolin inhibits the Gs-stimulated adenylate cyclase in rat ascites hepatoma AH66F cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Ascites; Cell Membrane; Colforsin; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Liver; Liver Neoplasms, Experimental; Manganese; Rats; Theophylline; Tumor Cells, Cultured | 1989 |
Effects of adenosine analogues on basal, prostaglandin E1- and forskolin-stimulated cyclic AMP formation in intact neuroblastoma cells.
Topics: Adenosine; Adenosine Deaminase; Alprostadil; Animals; Colforsin; Cyclic AMP; Mice; Neuroblastoma; Phenylisopropyladenosine; Receptors, Purinergic; Tumor Cells, Cultured | 1989 |
Platelet prostaglandin E1 hyposensitivity in schizophrenia: reduction of prostaglandin E1- or forskolin-stimulated cyclic AMP response in platelets.
Topics: Adenylyl Cyclases; Adult; Alprostadil; Blood Platelets; Colforsin; Cyclic AMP; Female; Humans; Male; Middle Aged; Schizophrenia | 1989 |
The local anaesthetic benzyl alcohol attenuates the alpha 2-adrenoceptor-mediated inhibition of human platelet adenylate cyclase activity when stimulated by prostaglandin E1, but not that stimulated by forskolin.
Topics: Adenylyl Cyclases; Alprostadil; Anesthetics, Local; Benzyl Alcohol; Benzyl Alcohols; Benzyl Compounds; Blood Platelets; Cell Membrane; Colforsin; Humans; Isoproterenol; Kinetics; Receptors, Adrenergic, alpha; Sodium Fluoride | 1989 |
Net fluid secretion by mammalian renal epithelial cells: stimulation by cAMP in polarized cultures derived from established renal cells and from normal and polycystic kidneys.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Epithelium; Humans; Kidney; Polycystic Kidney Diseases; Signal Transduction | 1989 |
Lymphocyte adenylate cyclase activity in immunosuppressed patients.
Topics: Adenylyl Cyclases; Adult; Alprostadil; Cell Membrane; Colforsin; Cyclosporins; Female; Glucocorticoids; Humans; Immunosuppression Therapy; Kidney Transplantation; Lymphocytes; Male; Middle Aged; Renal Dialysis; Uremia | 1989 |
Cyclic AMP signal transduction in posttraumatic stress disorder.
Topics: Adenylyl Cyclases; Adult; Alprostadil; Aluminum; Aluminum Chloride; Aluminum Compounds; Blood Platelets; Cell Membrane; Chlorides; Colforsin; Cyclic AMP; Humans; Isoproterenol; Lymphocytes; Middle Aged; Receptors, Adrenergic, beta; Stress Disorders, Post-Traumatic | 1987 |
Prostaglandin E1 and forskolin antagonize C-kinase activation in the human platelet.
Topics: Alprostadil; Blood Platelets; Calcium; Colforsin; Cyclic AMP; Diglycerides; Enzyme Activation; Humans; In Vitro Techniques; Phosphorylation; Protein Kinase C; Serotonin | 1987 |
Protein kinases induce isoproterenol desensitization of beta-adrenoceptor-coupled adenylate cyclase system: significance of receptor occupancy.
Topics: Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Bucladesine; Colforsin; Cyclic AMP; Dihydroalprenolol; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Male; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Reticulocytes; Theophylline | 1987 |
Effect of forskolin and prostaglandin E1 on stimulus secretion coupling in cultured bovine adrenal chromaffin cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenal Glands; Alprostadil; Animals; Bucladesine; Calcimycin; Calcium; Cattle; Chromaffin System; Colforsin; Cyclic AMP; Drug Synergism; Nicotine; Norepinephrine; Potassium | 1988 |
1,25-Dihydroxycholecalciferol induces an increase in PGE1- and forskolin-stimulated cyclic-AMP production in T47D human breast cancer cell line.
Topics: Alprostadil; Breast Neoplasms; Calcitriol; Cell Division; Colforsin; Cyclic AMP; Humans; Tumor Cells, Cultured | 1987 |
Efficacy and tolerance of narcotic analgesics at the mu opioid receptor in differentiated human neuroblastoma cells.
Topics: Adenylyl Cyclases; Algorithms; Alprostadil; Analgesics; Cell Differentiation; Cell Line; Colforsin; Humans; Morphine; Narcotics; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tretinoin | 1988 |
Regulation of sodium-dependent phosphate transport by parathyroid hormone in opossum kidney cells: adenosine 3',5'-monophosphate-dependent and -independent mechanisms.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Biological Transport; Bucladesine; Cell Line; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Kidney; Kinetics; Opossums; Parathyroid Hormone; Peptide Fragments; Phosphates; Sodium; Teriparatide; Vasoactive Intestinal Peptide | 1988 |
Prostaglandin-sensitive adenylyl cyclase of cultured preadipocytes and mature adipocytes of the rat: probable role of Gi in determination of stimulatory or inhibitory action.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Cholera Toxin; Colforsin; Cyclic AMP; Fibroblasts; GTP-Binding Proteins; Guanosine Triphosphate; Lung; Male; Membranes; Pertussis Toxin; Prostaglandins; Rats; Rats, Inbred F344; Sodium; Virulence Factors, Bordetella | 1988 |
Arachidonic acid and cyclic adenosine monophosphate stimulation of c-fos expression by a pathway independent of phorbol ester-sensitive protein kinase C.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Colforsin; Cyclic AMP; Mice; Platelet-Derived Growth Factor; Protein Kinase C; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
Differential effects of fluoride on adenylate cyclase activity and guanine nucleotide regulation of agonist high-affinity receptor binding.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Anura; Cell Membrane; Cells, Cultured; Colforsin; Dihydroalprenolol; Epinephrine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Iodocyanopindolol; Isoproterenol; Pindolol; Receptors, Adrenergic, beta; Sodium Fluoride; Yohimbine | 1988 |
Homologous vs. heterologous desensitization of the adenylate cyclase system in heart cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Isoproterenol; Myocardium; Norepinephrine; Propanolamines; Receptors, Adrenergic, beta | 1988 |
Role of adenosine 3'5'-cyclic monophosphate in antineoplastic effect of prostaglandins (PGE1, PGE2, PGD2 and PGA1) on human neuroblastoma cells.
Topics: Alprostadil; Cell Survival; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Neuroblastoma; Prostaglandin D2; Prostaglandins; Prostaglandins A; Tumor Cells, Cultured | 1988 |
Effects of chronic exposure to ethanol on the prostaglandin E1 receptor-mediated response and binding in a murine neuroblastoma clone (N1E-115).
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cells, Cultured; Clone Cells; Colforsin; Cyclic AMP; Ethanol; Guanine Nucleotides; Kinetics; Mice; Neuroblastoma; Receptors, Prostaglandin; Receptors, Prostaglandin E; Sucrose | 1986 |
Biological effect of anti-fucosyl GM1 ganglioside antibody on cyclic adenosine 3',5'-monophosphate production in FRTL5 rat thyroid cells.
Topics: Alprostadil; Animals; Antibody Specificity; Binding Sites; Cell Line; Colforsin; Cyclic AMP; G(M1) Ganglioside; Immunoglobulin G; Immunoglobulins, Thyroid-Stimulating; Rats; Receptors, Thyrotropin; Thyroid Gland; Thyrotropin | 1987 |
The influence of activating hormones on human platelet membrane Ca2+-ATPase activity.
Topics: Adenosine Diphosphate; Alprostadil; Blood Platelets; Calcimycin; Calcium-Transporting ATPases; Cell Membrane; Colforsin; Ethers; Humans; Ionomycin; Kinetics; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Vasopressins | 1986 |
Inhibitory effect of atrial natriuretic factor on adenylate cyclase activity in adrenal cortical membranes.
Topics: Adenylyl Cyclase Inhibitors; Adrenal Cortex; Adrenocorticotropic Hormone; Alprostadil; Animals; Atrial Natriuretic Factor; Cell Membrane; Colforsin; Diterpenes; Dopamine; Isoproterenol; Muscle Proteins; Prostaglandins E; Rats; Rats, Inbred Strains | 1985 |
Regulation of cyclic AMP metabolism by muscarinic cholinergic receptors.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alprostadil; Animals; Bacterial Toxins; Calcium; Cell Line; Colforsin; Cyclic AMP; Diterpenes; Humans; Isoproterenol; Kinetics; Mice; Molecular Weight; Oxotremorine; Phosphodiesterase Inhibitors; Prostaglandins E; Receptors, Adrenergic, beta; Receptors, Muscarinic; Virulence Factors, Bordetella | 1985 |
Inhibition of cyclic AMP formation by iodide in suspension cultures of porcine thyroid follicle cells.
Topics: Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Cell Membrane; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; Dose-Response Relationship, Drug; Iodides; Methimazole; Prostaglandins E; Swine; Thyroid Gland; Thyrotropin | 1985 |
Interaction between prostaglandin E1 and forskolin in modulation of cyclic AMP levels in rat epididymal adipocytes.
Topics: Adenosine Deaminase; Adipose Tissue; Alprostadil; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Drug Synergism; Epididymis; Epinephrine; Male; Meclofenamic Acid; Prostaglandins E; Rats; Rats, Inbred Strains | 1985 |
Heritability of forskolin and hormone-stimulated adenylate cyclase activity in human lymphocytes.
Topics: Adenylyl Cyclases; Adolescent; Adult; Alprostadil; Colforsin; Diterpenes; Enzyme Activation; Female; Humans; Isoproterenol; Lymphocytes; Male; Pregnancy; Prostaglandins E; Receptors, Adrenergic, beta; Twins, Monozygotic | 1985 |
Atrial natriuretic factor inhibits the early pathway of steroid biosynthesis in bovine adrenal cortex.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Alprostadil; Angiotensin II; Animals; Atrial Natriuretic Factor; Cattle; Cells, Cultured; Colforsin; Corticosterone; Desoxycorticosterone; Hydrocortisone; Progesterone | 1985 |
Refractoriness of platelets to prostaglandins after infusion in rabbits.
Topics: 6-Ketoprostaglandin F1 alpha; Adenylyl Cyclases; Alprostadil; Animals; Blood Platelets; Bucladesine; Colforsin; Cyclic AMP; Epoprostenol; Male; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Rabbits; Receptors, Epoprostenol; Receptors, Prostaglandin | 1985 |
Effect of forskolin on platelet deaggregation and cyclic AMP generation.
Topics: Adenosine Diphosphate; Alprostadil; Blood Platelets; Colforsin; Collagen; Cyclic AMP; Drug Synergism; Epoprostenol; Humans; In Vitro Techniques; Phosphorylation; Platelet Aggregation; Proteins | 1985 |
Adenosine 3',5'-cyclic-monophosphate-dependent regulation of alpha 1-adrenergic receptor number in rabbit aortic smooth muscle cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Aorta; Calcium; Colforsin; Cyclic AMP; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Tritium | 1986 |
Inhibition of Ns-stimulated human platelet adenylate cyclase by forskolin.
Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Alprostadil; Blood Platelets; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Ethylmaleimide; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Magnesium; Manganese; Thionucleotides | 1986 |
Phorbol esters enhance basal and stimulated adenylate cyclase activity in a pituitary cell line.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Activation; GTP-Binding Proteins; Phorbol Esters; Pituitary Gland; Protein Kinase C; Rats | 1986 |
Potentiation of prostaglandin E1-stimulated cAMP formation by 12-O-tetradecanoylphorbol-13-acetate in BALB/c mouse 3T3 cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Kinetics; Mice; Phorbols; Tetradecanoylphorbol Acetate | 1986 |
Inhibition of human neutrophil degranulation by forskolin in the presence of phosphodiesterase inhibitors.
Topics: Alprostadil; Calcimycin; Colforsin; Cyclic AMP; Cytoplasmic Granules; Glucuronidase; Humans; In Vitro Techniques; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Radioimmunoassay; Time Factors | 1986 |
Hormone and forskolin-stimulated cyclic AMP accumulation in human lymphocytes: reliability of longitudinal time measurements.
Topics: Adult; Alprostadil; Colforsin; Cyclic AMP; Female; Humans; Isoproterenol; Lymphocytes; Male; Sex Factors; Time Factors | 1986 |
Effects of prostaglandin E1, isoproterenol and forskolin on cyclic AMP levels and tension in rabbit aortic rings.
Topics: Alprostadil; Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Rabbits | 1986 |
Atrial natriuretic factor receptors are negatively coupled to adenylate cyclase in cultured atrial and ventricular cardiocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Animals, Newborn; Cells, Cultured; Colforsin; Dopamine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart Atria; Heart Ventricles; Isoproterenol; Myocardium; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Thionucleotides | 1986 |
Effect of age on the formation of cyclic nucleotides in guinea-pig tracheal smooth muscle in response to pharmacological agents.
Topics: Aging; Alprostadil; Animals; Carbachol; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Nitroprusside; Potassium; Trachea | 1986 |
Experimental model of anaphylaxis-induced beta-adrenergic blockade in the airways.
Topics: Alprostadil; Aminophylline; Anaphylaxis; Animals; Colforsin; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Ovalbumin; Receptors, Adrenergic, beta; Trachea | 1986 |
Phorbol ester-induced augmentation and inhibition of epinephrine-stimulated adenylate cyclase in S49 lymphoma cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Cells, Cultured; Colforsin; Cyclic AMP; Epinephrine; Guanylyl Imidodiphosphate; Lymphoma; Pertussis Toxin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1986 |
Adenosine receptors on human lymphocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Alprostadil; Binding Sites; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Histamine; Humans; In Vitro Techniques; Isoproterenol; Lymphocytes; Manganese; Neutrophils; Receptors, Purinergic; Theophylline; Vidarabine | 1986 |
Clonal variation in response to adrenocorticotropin in cultured bovine adrenocortical cells: relationship to senescence.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Alprostadil; Animals; Cattle; Cell Division; Cell Survival; Cells, Cultured; Clone Cells; Colforsin; Cyclic AMP; Kinetics; Male | 1986 |
Agents that elevate cAMP levels in platelets decrease thrombin binding.
Topics: Alprostadil; Animals; Blood Platelets; Colforsin; Cyclic AMP; Female; Humans; Phosphates; Phosphatidic Acids; Phosphoproteins; Phosphorylation; Rabbits; Serotonin; Theophylline; Thrombin | 1987 |
Tumor promoters as probes of protein kinase C in dog thyroid cell: inhibition of the primary effects of carbamylocholine and reproduction of some distal effects.
Topics: Alprostadil; Animals; Carbachol; Colforsin; Cyclic AMP; Diglycerides; Dogs; Phorbol Esters; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1987 |
Beta-adrenergic receptors and cyclic adenosine monophosphate generation in human fetal lung.
Topics: Alprostadil; Colforsin; Cyclic AMP; Gestational Age; Humans; Iodocyanopindolol; Isoproterenol; Lung; Pindolol; Propanolamines; Receptors, Adrenergic, beta | 1987 |
Thyroid effects on adenosine 3',5'-monophosphate levels and adenylate cyclase in cultured neuroblastoma cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Astrocytoma; Cell Line; Colforsin; Cyclic AMP; Glioma; Guanylyl Imidodiphosphate; Kinetics; Neuroblastoma; Thyroid Hormones; Thyroxine; Triiodothyronine | 1987 |
Activators of adenylate cyclase and cyclic AMP prolong calcium-dependent action potentials of mouse sensory neurons in culture by reducing a voltage-dependent potassium conductance.
Topics: Action Potentials; Adenylyl Cyclases; Alprostadil; Animals; Calcium; Cells, Cultured; Cesium; Cholera Toxin; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Electric Conductivity; Enzyme Activation; Mice; Neurons, Afferent; Potassium; Reaction Time; Theophylline | 1987 |
Ketotifen increases cyclic adenosine 3',5'-monophosphate in intact human lymphocyte and potentiates other adenylate cyclase activating agents.
Topics: Adenylyl Cyclases; Alprostadil; Colforsin; Cyclic AMP; Drug Synergism; Humans; Hydrocortisone; Isoproterenol; Ketotifen; Lymphocytes | 1987 |
Protein kinase C activation enhances cAMP accumulation in Swiss 3T3 cells: inhibition by pertussis toxin.
Topics: Adenylate Cyclase Toxin; Alprostadil; Animals; Arginine Vasopressin; Carcinogens; Cells, Cultured; Colforsin; Cyclic AMP; Diglycerides; Kinetics; Mice; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Virulence Factors, Bordetella | 1987 |
Multiple effects of phorbol esters on hormone-sensitive adenylate cyclase activity in S49 lymphoma cells.
Topics: Adenylyl Cyclases; Alprostadil; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Lymphoma; Phorbol Esters; Protein Kinase C; Receptors, Adrenergic, beta; Sodium Fluoride; Temperature; Tetradecanoylphorbol Acetate | 1987 |
Identification of glycoprotein Ib beta as one of the major proteins phosphorylated during exposure of intact platelets to agents that activate cyclic AMP-dependent protein kinase.
Topics: Actin Cytoskeleton; Actins; Adult; Alprostadil; Bernard-Soulier Syndrome; Blood Platelets; Colforsin; Cyclic AMP; Enzyme Activation; Epoprostenol; Humans; Phosphorylation; Platelet Membrane Glycoproteins; Protein Kinases | 1987 |
Regulation of hormone-stimulated cyclic AMP accumulation in intact human mononuclear leukocytes by blood plasma.
Topics: Adenosine Triphosphate; Adenylate Cyclase Toxin; Alprostadil; Cold Temperature; Colforsin; Cyclic AMP; GTP-Binding Proteins; Histamine; Humans; Isoproterenol; Lymphocytes; Monocytes; Virulence Factors, Bordetella | 1986 |
Guanine nucleotide-independent inhibition of adenylate cyclase by a stimulatory hormone.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Alprostadil; Cell Membrane; Colforsin; Ethylmaleimide; Fluorides; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Thionucleotides; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1988 |
Increase in vascular permeability of rat and guinea pig skin by T-kinin.
Topics: Alprostadil; Animals; Bradykinin; Capillary Permeability; Captopril; Colforsin; Dose-Response Relationship, Drug; Exudates and Transudates; Guinea Pigs; Rats; Rats, Inbred Strains; Skin | 1988 |
Synergistic effects of butyrate on platelet responses to arachidonate, A23187, PGE1, and forskolin.
Topics: Alprostadil; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Butyrates; Calcimycin; Calcium; Colforsin; Drug Synergism; Fluorescence Polarization; Humans; In Vitro Techniques; Platelet Aggregation; Serotonin | 1986 |
Adenylate cyclase activity of NIH 3T3 cells morphologically transformed by ras genes.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Colforsin; Enzyme Activation; GTP-Binding Proteins; Harvey murine sarcoma virus; Isoproterenol; Mice; Oncogenes | 1986 |
A novel site of action of a high affinity A1 adenosine receptor antagonist.
Topics: Adenylyl Cyclases; Adipose Tissue; Alprostadil; Animals; Colforsin; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Xanthines | 1988 |
Evidence for a GTP-binding protein involved in interferon-gamma transduction signal.
Topics: Adenylate Cyclase Toxin; Alprostadil; Animals; Binding, Competitive; Cholera Toxin; Colforsin; GTP-Binding Proteins; Interferon-gamma; Mice; Permeability; Pertussis Toxin; Recombinant Proteins; Signal Transduction; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1988 |
Inhibition of adenylate cyclase activity during the reversible shape change in human platelets.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Blood Platelets; Cell Membrane; Colforsin; Guanylyl Imidodiphosphate; Humans; Platelet Aggregation | 1988 |
Binding of [3H]forskolin to human platelet membranes. Regulation by guanyl-5'-yl imidodiphosphate, NaF, and prostaglandins E1 and D2.
Topics: Alprostadil; Binding Sites; Blood Platelets; Cell Membrane; Colforsin; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Kinetics; Prostaglandin D2; Prostaglandins D; Sodium Fluoride | 1986 |
Forskolin sensitizes human platelet adenylate cyclase to modulation of substrate (MgATP) affinity by hormones.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Alprostadil; Blood Platelets; Cell Membrane; Colforsin; Epinephrine; Humans; In Vitro Techniques; Kinetics | 1986 |
Age dependence of adenylate cyclase in guinea pig ureter homogenate.
Topics: Adenylyl Cyclases; Aging; Alprostadil; Animals; Colforsin; Enzyme Activation; Ethanol; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Male; Muscle Contraction; Propranolol; Sodium Fluoride; Ureter | 1986 |
Activation of cyclic AMP dependent protein kinase in rabbit aortic rings by prostaglandin E1 and forskolin is accompanied by contraction and relaxation, respectively.
Topics: Alprostadil; Animals; Aorta; Colforsin; Enzyme Activation; In Vitro Techniques; Muscle Contraction; Protein Kinases; Rabbits | 1986 |
Involvement of both inhibitory and stimulatory guanine nucleotide binding proteins in the expression of chronic opiate regulation of adenylate cyclase activity in NG108-15 cells.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Colforsin; Etorphine; Glioma; GTP-Binding Proteins; Hybrid Cells; Kinetics; Mice; Morphinans; Neuroblastoma; Rats; Sodium Fluoride | 1985 |
Forskolin induction of S-100 protein in glioma and hybrid cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Colforsin; Cycloheximide; Dactinomycin; Diterpenes; Glioma; Hybrid Cells; Isoproterenol; Kinetics; Mice; Neuroblastoma; Prostaglandins E; Rats; S100 Proteins; Theophylline | 1985 |
Regulation of [3H]forskolin binding to human platelet membranes by GppNHp, NaF, and prostaglandin E1.
Topics: Alprostadil; Binding Sites; Blood Platelets; Cell Membrane; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Kinetics; Prostaglandins E; Sodium Fluoride | 1985 |
Modulation of adenylate cyclase of human platelets by phorbol ester. Impairment of the hormone-sensitive inhibitory pathway.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Blood Platelets; Catalysis; Colforsin; Diterpenes; Enzyme Activation; Epinephrine; Guanosine Triphosphate; Humans; Phorbols; Prostaglandins E; Tetradecanoylphorbol Acetate; Thrombin | 1985 |
Protein kinase C interferes with Ni-mediated inhibition of human platelet adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Blood Platelets; Cell Membrane; Chickens; Colforsin; Enzyme Activation; Epinephrine; Female; Guanosine Triphosphate; Humans; Oviducts; Protein Kinase C; Tetradecanoylphorbol Acetate | 1985 |
Characterization of the homologous and heterologous desensitization of rat Leydig-tumour-cell adenylate cyclase.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Bucladesine; Centrifugation, Density Gradient; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; In Vitro Techniques; Isoproterenol; Kinetics; Leydig Cell Tumor; Luteinizing Hormone; Prostaglandins E; Rats | 1984 |
Specific receptor-mediated inhibition by synthetic atrial natriuretic factor of hormone-stimulated steroidogenesis in cultured bovine adrenal cells.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Alprostadil; Angiotensin II; Animals; Cattle; Cells, Cultured; Colforsin; Diterpenes; Hydrocortisone; Natriuretic Agents; Prostaglandins E; Proteins; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface | 1984 |
Effect of thyrotropin-releasing hormone on dog thyroid in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alprostadil; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; Dogs; In Vitro Techniques; Iodides; Kinetics; Prostaglandins E; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone | 1983 |
Pertussis toxin actions on the pituitary-derived 235-1 clone: effects of PGE1, cholera toxin, and forskolin on cyclic AMP metabolism and prolactin release.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Bacterial Toxins; Cells, Cultured; Cholera Toxin; Clone Cells; Colforsin; Cyclic AMP; Diterpenes; Male; Pertussis Toxin; Pituitary Gland, Anterior; Pituitary Neoplasms; Prolactin; Prostaglandins E; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1983 |
Inhibition of platelet alpha-granule release in vitro by forskolin.
Topics: Adenylyl Cyclases; Adult; Alprostadil; beta-Thromboglobulin; Blood Platelets; Colforsin; Diterpenes; Enzyme Activation; Female; Humans; In Vitro Techniques; Male; Platelet Factor 4; Prostaglandins E | 1984 |
Forskolin stimulates adenylate cyclase and iodine metabolism in thyroid.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; Dogs; Iodine; Prostaglandins E; Thyroid Gland; Thyrotropin | 1982 |
The cytoplasmic concentration of free calcium in platelets is controlled by stimulators of cyclic AMP production (PGD2, PGE1, forskolin).
Topics: Alprostadil; Blood Platelets; Calcium; Chemical Phenomena; Chemistry; Colforsin; Cyclic AMP; Cytoplasm; Diterpenes; Humans; In Vitro Techniques; Prostaglandin D2; Prostaglandins; Prostaglandins D; Prostaglandins E; Spectrometry, Fluorescence | 1983 |
Effect of forskolin on primary cultures of astrocytes and oligodendrocytes.
Topics: Alprostadil; Animals; Astrocytes; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Isoproterenol; Neuroglia; Oligodendroglia; Phenylephrine; Prostaglandins E; Rats; Stimulation, Chemical | 1983 |
Effects of forskolin analogs, phosphodiesterase inhibitors and 8-bromo cyclic AMP on plasma exudations induced with bradykinin and prostaglandin E1 in rat skin.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Bradykinin; Colforsin; Cyclic AMP; Diterpenes; Male; Phosphodiesterase Inhibitors; Plasma; Prostaglandins E; Rats; Rats, Inbred Strains; Skin | 1984 |
Distinct mechanisms of forskolin-stimulated cyclic AMP accumulation and forskolin-potentiated hormone responses in C6-2B cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Astrocytoma; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Isoproterenol; Kinetics; Prostaglandins E; Rats; Receptors, Adrenergic, beta | 1984 |
The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Properties and function of the purified protein.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Antihypertensive Agents; Bacterial Toxins; Blood Platelets; Cell Membrane; Colforsin; Diterpenes; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Magnesium; Molecular Weight; Pertussis Toxin; Prostaglandins E; Receptors, Cell Surface; Sodium Fluoride; Thionucleotides; Virulence Factors, Bordetella | 1984 |
Effect of forskolin on alterations of vascular permeability induced with bradykinin, prostaglandin E1, adenosine, histamine and carrageenin in rats.
Topics: Adenosine; Alprostadil; Animals; Bradykinin; Bromelains; Capillary Permeability; Carrageenan; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Edema; Foot Diseases; Histamine; Indomethacin; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Skin | 1983 |
Effect of thyrotropin-induced desensitization of bovine thyroid adenylate cyclase on the nucleotide regulatory protein.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adenylyl Imidodiphosphate; Alprostadil; Animals; Cattle; Cholera Toxin; Colforsin; Diterpenes; Drug Tolerance; Guanosine Triphosphate; Prostaglandins E; Thyroid Gland; Thyrotropin | 1983 |
Inhibition of forskolin activated adenylate cyclase in hamster adipocyte membranes with prostaglandin E1 and clonidine.
Topics: Adenylyl Cyclases; Adipose Tissue; Alprostadil; Animals; Antihypertensive Agents; Cell Membrane; Clonidine; Colforsin; Cricetinae; Diterpenes; Enzyme Activation; Kinetics; Male; Mesocricetus; Prostaglandins E | 1982 |
Synergistic inhibition of platelet aggregation by forskolin plus PGE1 or 2-fluoroadenosine: effects of 2',5'-dideoxyadenosine and 5'-methylthioadenosine.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Alprostadil; Colforsin; Deoxyadenosines; Dideoxyadenosine; Diterpenes; Drug Synergism; Humans; In Vitro Techniques; Platelet Aggregation; Prostaglandins E; Thionucleosides | 1982 |
Regulation of adenylate cyclase of human platelet membranes by forskolin.
Topics: Adenylyl Cyclases; Adult; Alprostadil; Antihypertensive Agents; Blood Platelets; Cell Membrane; Cholera Toxin; Colforsin; Diterpenes; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Kinetics; Male; Prostaglandins E; Sodium Fluoride; Thionucleotides | 1982 |
Hydrogen peroxide-induced increase in lung endothelial and epithelial permeability--effect of adenylate cyclase stimulation and phosphodiesterase inhibition.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Capillary Permeability; Colforsin; Endothelium, Vascular; Epithelium; Female; Hydrogen Peroxide; In Vitro Techniques; L-Lactate Dehydrogenase; Lung; Lung Injury; Male; Perfusion; Permeability; Phosphodiesterase Inhibitors; Potassium; Pulmonary Circulation; Pyridazines; Rabbits | 1995 |
Vasoactive agonists do not change the caliber of retinal capillaries of the rat.
Topics: Alprostadil; Animals; Capillaries; Colforsin; Endothelins; Epinephrine; Male; Microscopy, Electron; Rats; Rats, Sprague-Dawley; Retinal Vessels; Vasoconstriction; Vasoconstrictor Agents | 1995 |
Nimesulide, a sulfonanilide nonsteroidal anti-inflammatory drug, inhibits mediator release from human basophils and mast cells.
Topics: Adolescent; Adult; Alprostadil; Amino Acid Sequence; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basophils; Bryostatins; Calcimycin; Colforsin; Complement C5a; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Lactones; Leukotriene C4; Lung; Macrolides; Mast Cells; Middle Aged; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Prostaglandin D2; Skin; Sulfonamides; Tetradecanoylphorbol Acetate | 1993 |
Increased platelet reactivity to prostaglandin E1 in hypertension is linked with altered signal transduction.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Blood Platelets; Colforsin; Cyclic AMP; GTP Phosphohydrolases; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction | 1993 |
YC-1, a novel activator of platelet guanylate cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Alprostadil; Animals; Bleeding Time; Blood Platelets; Calcium; Colforsin; Collagen; Cyclic AMP; Cyclic GMP; Drug Interactions; Enzyme Activation; Guanylate Cyclase; Imidazoles; Indazoles; Indomethacin; Methemoglobin; Mice; Molecular Structure; Nitroprusside; Phosphoric Diester Hydrolases; Platelet Aggregation Inhibitors; Prostaglandin D2; Rabbits; Superoxide Dismutase; Thromboxane A2 | 1994 |
Cyclic AMP elevating agents synergize with inflammatory cytokines to induce an inducible type of nitric oxide synthase in cultured vascular smooth muscle cells.
Topics: Alprostadil; Amino Acid Oxidoreductases; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cytokines; Drug Synergism; Enzyme Induction; Epoprostenol; Gene Expression; In Vitro Techniques; Interferon-gamma; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Rats; RNA, Messenger | 1995 |
Iloprost-induced inhibition of proliferation of coronary artery smooth muscle cells is abolished by homologous desensitization.
Topics: Alprostadil; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cell Division; Cells, Cultured; Colforsin; Coronary Vessels; Female; Fluorides; Iloprost; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Time Factors | 1995 |
Inhibition of luteinizing hormone-releasing hormone secretion by delta-opioid agonists in GT1-1 neuronal cells.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alprostadil; Amino Acid Sequence; Cell Line; Colforsin; Culture Media, Conditioned; Dinoprostone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gonadotropin-Releasing Hormone; Molecular Sequence Data; Naltrexone; Narcotic Antagonists; Neurons; Pyrrolidines; Receptors, Opioid, delta | 1995 |
Evaluation of the use of the luciferase-reporter-gene system for gene-regulation studies involving cyclic AMP-elevating agents.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adolescent; Adult; Alprostadil; Cells, Cultured; Child; Chloramphenicol O-Acetyltransferase; Colforsin; Cyclic AMP; Gene Expression Regulation, Enzymologic; Genes, Reporter; Humans; Luciferases; Middle Aged; Muscle, Smooth, Vascular | 1995 |
Effect of the diglyceride lipase inhibitor, RG80267, on epithelial chloride secretion induced by various agents.
Topics: Alprostadil; Analysis of Variance; Arachidonic Acid; Cell Line; Chlorides; Colforsin; Colon; Cyclohexanones; Epithelium; Humans; Kinetics; Lipoprotein Lipase; Time Factors; Vasoactive Intestinal Peptide | 1995 |
Dissociation of cAMP-stimulated mitogenesis from activation of the mitogen-activated protein kinase cascade in Swiss 3T3 cells.
Topics: 3T3 Cells; Alprostadil; Amino Acid Sequence; Animals; Colforsin; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Immunosuppressive Agents; Mice; Mitogens; Molecular Sequence Data; Polyenes; Protein Kinases; Signal Transduction; Sirolimus; Transfection | 1995 |
Prostaglandins stimulate serotonin acetylation in chick pineal cells: involvement of cyclic AMP-dependent and calcium/calmodulin-dependent mechanisms.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylation; Alprostadil; Animals; Arylamine N-Acetyltransferase; Calcium; Calmodulin; Cells, Cultured; Chickens; Cloprostenol; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Indomethacin; Kinetics; Pineal Gland; Prostaglandins; Serotonin; Sulfonamides | 1993 |
cAMP inhibition of interleukin-1-induced interleukin-6 production by human lung fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Bucladesine; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Humans; Interleukin-1; Interleukin-6; Lung; RNA, Messenger; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1993 |
Role of cyclic AMP in promoting the thromboresistance of human endothelial cells by enhancing thrombomodulin and decreasing tissue factor activities.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Base Sequence; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dibutyryl Cyclic GMP; Endothelium, Vascular; Humans; Immunoenzyme Techniques; Kinetics; Microscopy, Immunoelectron; Molecular Sequence Data; Polymerase Chain Reaction; Receptors, Cell Surface; Receptors, Thrombin; RNA; RNA-Directed DNA Polymerase; Saphenous Vein; Thrombin; Thromboplastin; Thrombosis | 1993 |
Platelet serotonin studies in hyperserotonemic relatives of children with autistic disorder.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Alprostadil; Autistic Disorder; Biological Transport; Blood Platelets; Child; Colforsin; Cyclic AMP; Female; Humans; In Vitro Techniques; Lysergic Acid; Male; Paroxetine; Platelet Count; Receptors, Serotonin; Serotonin | 1993 |
Modulation of cyclic AMP production by strial marginal cells from gerbil in culture.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Alprostadil; Analysis of Variance; Animals; Cells, Cultured; Colforsin; Collagen; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Endolymph; Epinephrine; Gerbillinae; Immunohistochemistry; Isoproterenol; Male; Microscopy, Electron; Stria Vascularis; Vasopressins | 1994 |
Phosphorylation of focal adhesion vasodilator-stimulated phosphoprotein at Ser157 in intact human platelets correlates with fibrinogen receptor inhibition.
Topics: Adenosine Diphosphate; Alprostadil; Blood Platelets; Blood Proteins; Cell Adhesion Molecules; Colforsin; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; In Vitro Techniques; Kinetics; Membrane Proteins; Microfilament Proteins; Molsidomine; Nitroprusside; Phosphoproteins; Phosphoserine; Platelet Membrane Glycoproteins; Protein Kinases; Protein-Tyrosine Kinases; Serine; Vasodilator Agents | 1994 |
A proposal for purification of salivary polymorphonuclear leukocytes by combination of nylon mesh filtration and density-gradient method: a validation by superoxide- and cyclic AMP-generating responses.
Topics: Alprostadil; Cell Separation; Centrifugation, Density Gradient; Colforsin; Cyclic AMP; Filtration; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nylons; Saliva; Superoxides | 1994 |
Analysis of the adenylate cyclase signalling system, and alterations induced by culture with insulin, in a novel SV40-DNA-immortalized hepatocyte cell line (P9 cells).
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Cell Transformation, Viral; Colforsin; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Insulin; Liver; Male; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Signal Transduction | 1994 |
Characterization of cyclic AMP accumulation in cultured human corpus cavernosum smooth muscle cells.
Topics: Alprostadil; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Humans; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Penis; Receptors, Adrenergic, beta | 1994 |
Cyclic AMP- and phorbol ester-regulated Cl- permeabilities in primary cultures of human and rabbit colonocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Biological Transport; Bumetanide; Carrier Proteins; Cell Membrane Permeability; Cell Separation; Cells, Cultured; Chlorides; Colforsin; Colon; Cyclic AMP; Fluorescent Dyes; Furosemide; Humans; Indomethacin; Kinetics; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rabbits; Rectum; Sodium-Potassium-Chloride Symporters; Spectrometry, Fluorescence; Time Factors | 1994 |
Platelets from spontaneously hypertensive rats exhibit decreased expression of inhibitory guanine nucleotide regulatory protein. Relation with adenylyl cyclase activity.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Alprostadil; Animals; Blood Platelets; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1993 |
Third isoform of the prostaglandin-E-receptor EP3 subtype with different C-terminal tail coupling to both stimulation and inhibition of adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; DNA, Complementary; Gene Expression; GTP Phosphohydrolases; Mice; Molecular Sequence Data; Receptors, Prostaglandin E; RNA, Messenger; Second Messenger Systems; Transfection; Tumor Cells, Cultured | 1993 |
Lysophosphatidic acid mimics serum-induced sensitization of cyclic AMP accumulation.
Topics: Alprostadil; Animals; Astrocytoma; Blood; Colforsin; Cyclic AMP; Drug Interactions; Glioma; Humans; Isoproterenol; Lysophospholipase; Lysophospholipids; Pertussis Toxin; Phospholipases; Rats; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella | 1993 |
Guanine nucleotide regulatory protein alterations in young Milan hypertensive strain rats.
Topics: Adenylyl Cyclases; Alprostadil; Amino Acid Sequence; Animals; Cell Membrane; Cells, Cultured; Colforsin; GTP-Binding Proteins; Hypertension; Immune Sera; Isoproterenol; Molecular Sequence Data; Muscle, Smooth, Vascular; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Signal Transduction | 1994 |
Quantitative stoichiometry of the proteins of the stimulatory arm of the adenylyl cyclase cascade in neuroblastoma x glioma hybrid, NG108-15 cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Colforsin; Cyclic AMP; Glioma; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Hybrid Cells; Kinetics; Mice; Neuroblastoma; Rats; Receptors, Prostaglandin; Recombinant Proteins; Sodium Fluoride; Tumor Cells, Cultured | 1994 |
Transcription of the gene for parathyroid hormone-related peptide from the human is activated through a cAMP-dependent pathway by prostaglandin E1 in HTLV-I-infected T cells.
Topics: Alprostadil; Analysis of Variance; Bucladesine; Cell Line; Cell Transformation, Viral; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Gene Expression Regulation, Viral; Genes; Human T-lymphotropic virus 1; Humans; Kinetics; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Protein Biosynthesis; Proteins; RNA, Messenger; T-Lymphocytes; Time Factors; Transcription, Genetic | 1993 |
Okadaic acid induces both augmentation and inhibition of beta 2-adrenergic stimulation of cAMP accumulation in S49 lymphoma cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Ethers, Cyclic; Kinetics; Lymphoma; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Time Factors; Tumor Cells, Cultured | 1993 |
Effects of the phospholipid environment in the plasma membrane on receptor interaction with the adenylyl cyclase complex of intact cells.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Cell Membrane; Cholesterol; Colforsin; Cricetinae; Cricetulus; Enzyme Activation; Humans; Phosphatidylcholines; Phospholipids; Receptors, Adrenergic, alpha; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Sphingomyelins | 1993 |
Tumor necrosis factor produces homologous desensitization of lymphocyte beta 2-adrenergic responses.
Topics: Alprostadil; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Isoproterenol; Lymphocytes; Receptors, Adrenergic, beta; Shock, Septic; Tumor Necrosis Factor-alpha | 1993 |
Beta 2-adrenergic receptor mutants reveal structural requirements for the desensitization observed with long-term epinephrine treatment.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Colforsin; Cricetinae; Epinephrine; L Cells; Magnesium; Mice; Mutation; Receptors, Adrenergic, beta; Time Factors | 1993 |
Agonist-induced effects on cyclic AMP metabolism are affected in pigment epithelial cells of the Royal College of Surgeons rat.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Alprostadil; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Fibroblast Growth Factor 2; Imidazoles; Isoproterenol; Kinetics; Melatonin; Pigment Epithelium of Eye; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta-2; Receptors, Purinergic P1; Serotonin | 1995 |
Agents that elevate cAMP inhibit human neutrophil apoptosis.
Topics: Alprostadil; Apoptosis; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Enzyme Inhibitors; Humans; Isoquinolines; Neutrophils; Prostaglandins E, Synthetic; Receptors, IgG; Sulfonamides | 1995 |
Elevated intracellular cyclic AMP inhibits chemotaxis in human eosinophils.
Topics: Alprostadil; Chemotaxis, Leukocyte; Colforsin; Complement C5a; Cyclic AMP; Eosinophils; Humans; Phosphodiesterase Inhibitors; Platelet Activating Factor; Quinazolines | 1995 |
Effect of cesarean delivery on perioperative regulation of the beta-adrenergic receptor system of human lymphocytes.
Topics: Abdomen; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Alprostadil; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Colforsin; Cyclic AMP; Down-Regulation; Female; Humans; Iodine Radioisotopes; Isoproterenol; Lymphocytes; Pindolol; Pregnancy; Receptors, Adrenergic, beta; Stress, Physiological; Thoracic Surgery; Vasodilator Agents | 1996 |
Isoform-specific sensitization of adenylyl cyclase activity by prior activation of inhibitory receptors: role of beta gamma subunits in transducing enhanced activity of the type VI isoform.
Topics: Adenylyl Cyclases; Alprostadil; Carbachol; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dopamine Agonists; Enzyme Activation; Ergolines; Humans; Isoenzymes; Muscarinic Agonists; Quinpirole; Receptors, Muscarinic; Recombinant Proteins; Signal Transduction; Transducin | 1996 |
Forskolin: a promising new adjunct to intracavernous pharmacotherapy.
Topics: Alprostadil; Animals; Colforsin; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Hemodynamics; Male; Muscle, Smooth; Penis; Pressure | 1996 |
Effects of prostaglandins on deoxyribonucleic acid and aggrecan synthesis in the RCJ 3.1C5.18 chondrocyte cell line: role of second messengers.
Topics: Aggrecans; Alprostadil; Animals; Bucladesine; Calcium; Cartilage; Cell Line; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; DNA; Extracellular Matrix Proteins; Lectins, C-Type; Prostaglandins; Protein Kinase C; Proteoglycans; Rats; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1996 |
Comparison of effects of vasoactive agents on adenylate cyclase activity in endothelial and smooth muscle cells from the same specimen of fetal bovine aorta.
Topics: Adenine; Adenylyl Cyclases; Alprostadil; Animals; Aorta; Catecholamines; Cattle; Colforsin; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Norepinephrine | 1996 |
Differential regulation of receptor-stimulated cyclic adenosine monophosphate production by polyvalent cations in MC3T3-E1 osteoblasts.
Topics: Adenylate Cyclase Toxin; Alprostadil; Analysis of Variance; Cations; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Gadolinium; Norepinephrine; Osteoblasts; Parathyroid Hormone; Pertussis Toxin; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Protein Kinase C; Virulence Factors, Bordetella | 1996 |
Expression of functional muscarinic acetylcholine receptor subtypes in human corpus cavernosum and in cultured smooth muscle cells.
Topics: Adenylyl Cyclases; Alprostadil; Atropine; Carbachol; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Humans; In Situ Hybridization; Isoproterenol; Kinetics; Male; Models, Biological; Muscle, Smooth; Penis; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; RNA, Messenger; Transcription, Genetic | 1995 |
Dissociation of negative inotropic effect of carbachol from changes in cAMP and PKA in perfused rat hearts.
Topics: Alprostadil; Animals; Carbachol; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; In Vitro Techniques; Isoproterenol; Male; Muscarinic Agonists; Myocardial Contraction; Myocardium; Perfusion; Pressure; Rats; Rats, Wistar; Ventricular Function, Left | 1996 |
Cyclic AMP-dependent pathway that mediates suppressive regulation of glycosaminoglycan production in cultured vascular endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Aorta; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascular; Fibroblasts; Glucosamine; Glycosaminoglycans; Humans; L-Lactate Dehydrogenase; Swine | 1996 |
Involvement of pertussis toxin-sensitive and -insensitive G proteins in alpha-thrombin signalling on cultured human vascular smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Alprostadil; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Muscle, Smooth, Vascular; Pertussis Toxin; Phosphatidylinositols; Poly(ADP-ribose) Polymerases; Saponins; Signal Transduction; Thrombin; Virulence Factors, Bordetella | 1996 |
Involvement of the beta gamma subunits of inhibitory GTP-binding protein in chemoattractant receptor-mediated potentiation of cyclic AMP formation in guinea pig neutrophils.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Calcium; Cattle; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Guinea Pigs; Macromolecular Substances; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Signal Transduction; Type C Phospholipases | 1996 |
Evaluation of cyclic AMP accumulation in EBV-transformed human B-lymphocytes: effects of dopamine agonists, isoproterenol, prostaglandin E1, cholera toxin, forskolin, and phorbol 12-myristate-13 acetate.
Topics: Alprostadil; B-Lymphocytes; Cholera Toxin; Colforsin; Cyclic AMP; Dopamine Agonists; Dose-Response Relationship, Drug; Humans; Isoproterenol; Phorbol Esters | 1996 |
Regulation of expression of matrix metalloproteinase-9 in early human T cells of the HSB.2 cultured line by the EP3 subtype of prostaglandin E2 receptor.
Topics: Adenine; Alprostadil; Blotting, Northern; Bucladesine; Calcium; Cell Line; Colforsin; Collagenases; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Leukemia, T-Cell; Matrix Metalloproteinase 9; Misoprostol; Prostaglandins E, Synthetic; Receptors, Prostaglandin E; RNA, Messenger; T-Lymphocytes; Thapsigargin; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Inhibition of adenylyl cyclases by 12(S)-hydroxyeicosatetraenoic acid.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Cell Line; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Isoenzymes; Mice; Pertussis Toxin; Rats; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1996 |
Effect of adenosine 3',5'-cyclic monophosphate (cAMP) on human non-tumorigenic and tumorigenic parotid acinar cells in culture.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenoma, Pleomorphic; Alprostadil; Bucladesine; Cell Differentiation; Cell Division; Cell Size; Cell Transformation, Neoplastic; Cells, Cultured; Colforsin; Cyclic AMP; Humans; Parotid Gland; Parotid Neoplasms; Phosphodiesterase Inhibitors; Receptors, Prostaglandin E; Tumor Cells, Cultured | 1996 |
Role of potassium channels and nitric oxide in the effects of iloprost and prostaglandin E1 on hypoxic vasoconstriction in the isolated perfused lung of the rat.
Topics: Adenosine; Alprostadil; Animals; Colforsin; Enzyme Inhibitors; Hypoxia; Iloprost; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium Channels; Pulmonary Circulation; Rats; Rats, Wistar; Vasoconstriction; Vasodilator Agents | 1997 |
The influence of surgical preparation on cyclic nucleotide synthesis in an organ culture of human saphenous vein.
Topics: Acetylcholine; Adult; Aged; Alprostadil; Calcimycin; Colforsin; Coronary Artery Bypass; Cyclic AMP; Cyclic GMP; DNA; Humans; Middle Aged; Organ Culture Techniques; Radioimmunoassay; Saphenous Vein; Tunica Intima | 1997 |
Prostaglandin E1 stimulates interleukin-6 secretion via protein kinase A in osteoblast-like cells.
Topics: Alprostadil; Animals; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Interleukin-6; Isoquinolines; Mice; Osteoblasts; Sulfonamides | 1997 |
Role of protein kinase A in collagenase-1 gene regulation by prostaglandin E1: studies in a rabbit synoviocyte cell line, HIG-82.
Topics: Alprostadil; Animals; Cell Line; Colforsin; Collagenases; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Interleukin-1; Isoenzymes; Isoquinolines; Matrix Metalloproteinase 1; Protein Kinase C; Protein Kinase C-alpha; Rabbits; RNA, Messenger; Sulfonamides; Synovial Membrane; Thionucleotides; Transfection | 1997 |
Increased cyclic AMP response to forskolin in Epstein-Barr virus-transformed human B-lymphocytes derived from schizophrenics.
Topics: Adult; Alprostadil; B-Lymphocytes; Cell Transformation, Viral; Cholera Toxin; Colforsin; Cyclic AMP; Female; Herpesvirus 4, Human; Humans; Isoproterenol; Lymphocyte Activation; Male; Schizophrenia; Tetradecanoylphorbol Acetate | 1997 |
Regulation of stimulatory adenylyl cyclase signaling during forskolin-induced differentiation of mouse neuroblastoma x rat glioma (NG108-15) cells.
Topics: Adenylyl Cyclases; Alprostadil; Aluminum Compounds; Animals; Cell Differentiation; Colforsin; Fluorides; Glioma; GTP-Binding Proteins; Hybrid Cells; Mice; Neuroblastoma; Rats; Signal Transduction | 1997 |
The C-terminal domain of the human EP4 receptor confers agonist-induced receptor desensitization in a receptor hybrid with the rat EP3beta receptor.
Topics: Alprostadil; Animals; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Humans; Ligands; Prostaglandins E, Synthetic; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Recombinant Fusion Proteins; Transfection | 1997 |
Induction of human thioredoxin in cultured human retinal pigment epithelial cells through cyclic AMP-dependent pathway; involvement in the cytoprotective activity of prostaglandin E1.
Topics: Adenylyl Cyclases; Adult; Alprostadil; Bucladesine; Cell Survival; Cells, Cultured; Colforsin; Cryoprotective Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epoprostenol; Humans; Hydrogen Peroxide; Oxidants; Oxidative Stress; Pigment Epithelium of Eye; Signal Transduction; Thionucleotides; Thioredoxins | 1997 |
G-protein-coupled receptor agonists augment adenylyl cyclase activity induced by forskolin in human corpus cavernosum smooth muscle cells.
Topics: Adenylyl Cyclases; Alprostadil; Carbachol; Cells, Cultured; Colforsin; Drug Interactions; Enzyme Activation; GTP-Binding Proteins; Humans; Isoproterenol; Male; Models, Biological; Muscle Relaxation; Muscle, Smooth, Vascular; Penis; Phenylephrine; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Cholinergic; Signal Transduction | 1997 |
Triiodothyronine modulates interleukin-6 synthesis in osteoblasts: inhibitions in protein kinase A and C pathways.
Topics: Alprostadil; Animals; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Interleukin-1; Interleukin-6; Mice; Osteoblasts; Protein Kinase C; Tetradecanoylphorbol Acetate; Triiodothyronine | 1998 |
Phosducin expression in NG 108-15 hybrid cells enhances prostaglandin E1 stimulated adenylate cyclase activity.
Topics: Adenylyl Cyclases; Alprostadil; Blotting, Western; Colforsin; Cyclic AMP; Enzyme Activation; Eye Proteins; Glioma; GTP Phosphohydrolases; GTP-Binding Protein Regulators; Hybrid Cells; Neuroblastoma; Phosphoproteins; Radioligand Assay; Receptors, Cell Surface; Signal Transduction; Tumor Cells, Cultured | 1998 |
Elevation of cyclic AMP by iloprost and prostaglandin E1 increases cholesterol efflux and the binding capacity for high-density lipoproteins in human fibroblasts.
Topics: Alprostadil; Binding Sites; Biological Transport, Active; Cells, Cultured; Cholesterol; Colforsin; Cyclic AMP; Dinoprost; Fibroblasts; Humans; Iloprost; Kinetics; Lipoproteins, HDL; Lipoproteins, HDL3 | 1998 |
Activation of cardiac EP3 receptors by PGE1 reduces beta-adrenergic inotropic effects.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprostadil; Animals; Colforsin; Cyclic AMP; Isoproterenol; Myocardial Contraction; Myocardium; Radioligand Assay; Receptors, Adrenergic, beta; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Sarcolemma; Swine; Swine, Miniature; Tritium; Ventricular Function, Left | 1997 |
Effect of vitamin D3 on interleukin-6 synthesis induced by prostaglandins in osteoblasts.
Topics: Alprostadil; Animals; Bucladesine; Calcitriol; Carcinogens; Cell Line; Cholera Toxin; Colforsin; Dinoprost; Dose-Response Relationship, Drug; Interleukin-6; Mice; Osteoblasts; Tetradecanoylphorbol Acetate | 1998 |
Retinoic acid suppresses interleukin-6 synthesis induced by prostaglandins in osteoblasts.
Topics: Alprostadil; Animals; Bucladesine; Carcinogens; Cell Line; Cholera Toxin; Colforsin; Dinoprost; Dose-Response Relationship, Drug; Fibrinolytic Agents; Interleukin-1; Interleukin-6; Keratolytic Agents; Osteoblasts; Oxytocics; Prostaglandins; Tetradecanoylphorbol Acetate; Tretinoin | 1998 |
Adenylyl cyclase supersensitivity in opioid-withdrawn NG108-15 hybrid cells requires Gs but is not mediated by the Gsalpha subunit.
Topics: Adenylyl Cyclases; Alprostadil; Cell Line; Colforsin; GTP-Binding Protein alpha Subunits, Gs; Humans; Hybrid Cells; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Receptors, Opioid, delta; Receptors, Prostaglandin; Signal Transduction; Substance Withdrawal Syndrome | 1998 |
Sphingosine modulates interleukin-6 synthesis in osteoblasts.
Topics: Alprostadil; Animals; Bucladesine; Calcimycin; Cell Line; Cholera Toxin; Colforsin; Dinoprost; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Immunoenzyme Techniques; Interleukin-1; Interleukin-6; Mice; Osteoblasts; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
Cl- transport in an immortalized human epithelial cell line (NCM460) derived from the normal transverse colon.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Bacterial Toxins; Biological Transport; Cell Line, Transformed; Chlorides; Colforsin; Colon; Cyclic AMP; Cyclic GMP; Cystic Fibrosis Transmembrane Conductance Regulator; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Fluorescent Dyes; Histamine; Humans; Intestinal Mucosa; Models, Biological; Phorbol 12,13-Dibutyrate; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic | 1998 |
Role of EP2 receptors and cAMP in prostaglandin E2 regulated expression of type I collagen alpha1, lysyl oxidase, and cyclooxygenase-1 genes in human embryo lung fibroblasts.
Topics: Alprostadil; Animals; Cell Line; Colforsin; Collagen; Cyclic AMP; Cyclooxygenase 1; Dinoprostone; Fibroblasts; Gene Expression Regulation; Humans; Isoenzymes; Lung; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Protein-Lysine 6-Oxidase; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; Transforming Growth Factor beta | 1998 |
Differentiation of HL-60 promyelocytic leukemia cells is accompanied by a modification of magnesium homeostasis.
Topics: Adenosine Triphosphate; Alprostadil; Antiporters; Arachidonic Acid; Bucladesine; Calcimycin; Calcium; Cell Differentiation; Cell Membrane Permeability; Choline; Colforsin; Digitonin; Dimethyl Sulfoxide; HL-60 Cells; Homeostasis; Humans; Imipramine; Interferon-alpha; Magnesium; Neutrophils; Rotenone | 1998 |
Adenylyl cyclase, a coincidence detector for nitric oxide.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Blotting, Northern; Cell Membrane; Colforsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Kinetics; Nitric Oxide; Nitric Oxide Donors; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Tumor Cells, Cultured | 1999 |
Effect of ceramide on interleukin-6 synthesis in osteoblast-like cells.
Topics: Alprostadil; Animals; Bucladesine; Calcimycin; Cell Line; Cholera Toxin; Colforsin; Dinoprost; Interleukin-1; Interleukin-6; Mice; Osteoblasts; Sphingosine; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Tumor Necrosis Factor-alpha | 1999 |
Roles of prostaglandin E receptors in mesangial cells under high-glucose conditions.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Anti-Ulcer Agents; Blotting, Northern; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Gene Expression; Glomerular Mesangium; Glucose; Male; Menstruation-Inducing Agents; Phosphodiesterase Inhibitors; Prostaglandins E, Synthetic; Rats; Rats, Inbred WKY; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; RNA, Messenger; Thymidine; Tritium | 1999 |
Development of human and rabbit vaginal smooth muscle cell cultures: effects of vasoactive agents on intracellular levels of cyclic nucleotides.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Alprostadil; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Female; Humans; Isoproterenol; Muscle, Smooth; Nitroprusside; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Piperazines; Purines; Rabbits; Sildenafil Citrate; Sulfones; Vagina; Vasoactive Intestinal Peptide; Vasodilator Agents | 1999 |
Roles of atypical protein kinase C in lysophosphatidic acid-induced type II adenylyl cyclase activation in RAW 264.7 macrophages.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Alprostadil; Animals; Calcium; Cell Line; Cholera Toxin; Colchicine; Colforsin; Cyclic AMP; Cytochalasin B; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; GTP-Binding Proteins; Indoles; Isoenzymes; Isoproterenol; Lysophosphatidylcholines; Lysophospholipids; Macrophages; Pertussis Toxin; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1999 |
Reduction of infarct size by selective stimulation of prostaglandin EP(3)receptors in the reperfused ischemic pig heart.
Topics: Action Potentials; Adenylyl Cyclases; Adrenergic beta-Agonists; Alprostadil; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; CHO Cells; Colforsin; Coronary Vessels; Creatine Kinase; Cricetinae; Cricetulus; Cyclic AMP; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Heart Ventricles; Hemodynamics; Infusions, Intra-Arterial; Isoenzymes; Isoproterenol; Male; Muscle Proteins; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Second Messenger Systems; Staining and Labeling; Swine; Swine, Miniature; Transfection | 2000 |
Distinctive cyclic AMP-dependent protein kinase subunit localization is associated with cyst formation and loss of tubulogenic capacity in Madin-Darby canine kidney cell clones.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Clone Cells; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dogs; Hepatocyte Growth Factor; Kidney; Kidney Neoplasms; Kidney Tubules; Macromolecular Substances; Microscopy, Immunoelectron; Polycystic Kidney Diseases; Recombinant Proteins; Signal Transduction; Subcellular Fractions | 2000 |
Cyclic AMP regulates mRNA expression of alpha-1d and alpha-2a adrenergic receptors in cultured human corpus cavernosum smooth muscle cells.
Topics: Alprostadil; Cells, Cultured; Colforsin; Cyclic AMP; Gene Expression Regulation; Humans; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Penis; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; RNA, Messenger | 2000 |
Effects of latanoprost on tyrosinase activity and mitotic index of cultured melanoma lines.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Enzyme Induction; Enzyme-Linked Immunosorbent Assay; Humans; Intraocular Pressure; Latanoprost; Melanoma; Mice; Mitotic Index; Monophenol Monooxygenase; Pigmentation; Prostaglandins F, Synthetic; Skin Neoplasms; Stimulation, Chemical; Time Factors; Tumor Cells, Cultured; Uveal Neoplasms | 2000 |
Multiple signal transduction pathways through two prostaglandin E receptor EP3 subtype isoforms expressed in human uterus.
Topics: Alprostadil; Amino Acid Sequence; Animals; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Female; Humans; Molecular Sequence Data; Protein Isoforms; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Signal Transduction; Transcription, Genetic; Transfection; Uterus | 2000 |
Prostaglandins E2 and I2 downregulate tumor necrosis factor alpha-induced intercellular adhesion molecule-1 expression in human oral gingival epithelial cells.
Topics: Acetates; Adult; Alprostadil; Analysis of Variance; Benzhydryl Compounds; Bucladesine; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Epithelial Cells; Epoprostenol; Gene Expression Regulation; Gingiva; Humans; Intercellular Adhesion Molecule-1; Receptors, Prostaglandin E; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Tumor Necrosis Factor-alpha | 2000 |
Arg60 Leu mutation in the first cytoplasmic loop of the platelet thromboxane A2 receptor is not essential for mediating inhibitory coupling between the receptor and adenylyl cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adult; Alprostadil; Amino Acid Substitution; Arginine; Blood Platelet Disorders; Blood Platelets; Colforsin; Cyclic AMP; Cytoplasm; Female; Humans; Leucine; Male; Middle Aged; Mutation, Missense; Peptide Fragments; Protein Structure, Tertiary; Receptors, Thromboxane; Thromboxane A2 | 2000 |
Mechanisms involved in prostaglandin-induced increase in bone resorption in neonatal mouse calvaria.
Topics: Alprostadil; Animals; Animals, Newborn; Bone Resorption; Colforsin; Culture Techniques; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Mice; Misoprostol; Prostaglandins; Prostaglandins F, Synthetic; Skull | 2001 |
Characterization of PGE2 receptors in fetal and newborn lamb ductus arteriosus.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Alprostadil; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Anti-Ulcer Agents; Binding, Competitive; Biphenyl Compounds; Colforsin; Dinoprost; Ductus Arteriosus; Female; Fetus; Polymerase Chain Reaction; Potassium Channels; Pregnancy; Prostaglandin Antagonists; Prostaglandins E, Synthetic; Radioligand Assay; Receptors, Prostaglandin E; Sheep; Tritium; Vasoconstriction; Xanthenes; Xanthones | 2001 |
Regulation of prostacyclin and prostaglandin E(2) receptor mediated responses in adult rat dorsal root ganglion cells, in vitro.
Topics: Adenylyl Cyclases; Aging; Alprostadil; Animals; Antineoplastic Agents; Cell Count; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Down-Regulation; Enzyme Activation; Epoprostenol; Ganglia, Spinal; Iloprost; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, Epoprostenol; Receptors, Prostaglandin | 2001 |
Inhibition by adenylyl cyclase-cAMP system of ET-1-induced HSP27 in osteoblasts.
Topics: Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Blotting, Northern; Blotting, Western; Bucladesine; Cells, Cultured; Colforsin; Endothelin-1; Enzyme Inhibitors; Heat-Shock Proteins; Mice; Mitogen-Activated Protein Kinases; Molecular Chaperones; Neoplasm Proteins; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; RNA, Messenger | 2001 |
PGE(2) increases release of substance P from renal sensory nerves by activating the cAMP-PKA transduction cascade.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Animals; Bradykinin; Calcitonin Gene-Related Peptide; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Kidney Pelvis; Male; Neurons, Afferent; Peripheral Nerves; Pressure; Rats; Rats, Sprague-Dawley; Signal Transduction; Substance P | 2002 |
Role of the intracellular domains of GPIb in controlling the adhesive properties of the platelet GPIb/V/IX complex.
Topics: Alprostadil; Amino Acid Substitution; Animals; Antibodies, Monoclonal; Cattle; Cell Adhesion; CHO Cells; Colforsin; Cricetinae; Cricetulus; Humans; K562 Cells; Platelet Adhesiveness; Platelet Glycoprotein GPIb-IX Complex; Protein Interaction Mapping; Protein Subunits; Sequence Deletion; Transfection; von Willebrand Factor | 2003 |
Role of prostaglandin E2 receptors in migration of murine and human breast cancer cells.
Topics: Alprostadil; Animals; Breast Neoplasms; Carcinoma; Cell Movement; Colforsin; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Indoles; Isoenzymes; Mammary Neoplasms, Experimental; Membrane Proteins; Mice; Neoplasm Invasiveness; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Tumor Cells, Cultured; Up-Regulation; Xanthenes; Xanthones | 2003 |
Induction of hyaluronic acid synthase 2 (HAS2) in human vascular smooth muscle cells by vasodilatory prostaglandins.
Topics: 6-Ketoprostaglandin F1 alpha; Acetophenones; Alprostadil; Arteriosclerosis; Becaplermin; Benzopyrans; Bucladesine; Carotid Artery Diseases; Carotid Artery, Internal; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Enzyme Induction; Epoprostenol; Extracellular Matrix; Glucuronosyltransferase; Humans; Hyaluronan Synthases; Hyaluronic Acid; Iloprost; Indoles; Isoenzymes; Isoquinolines; Macrophages; Maleimides; Membrane Proteins; Muscle Cells; Muscle, Smooth, Vascular; Pertussis Toxin; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-sis; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; RNA, Small Interfering; Sulfonamides; Vasodilator Agents | 2004 |
Prostacyclin induces apoptosis of vascular smooth muscle cells by a cAMP-mediated inhibition of extracellular signal-regulated kinase activity and can counteract the mitogenic activity of endothelin-1 or basic fibroblast growth factor.
Topics: Alprostadil; Animals; Apoptosis; Butadienes; Caspase 3; Caspases; Cell Division; Colforsin; Endothelin-1; Enzyme Activation; Epoprostenol; Fibroblast Growth Factor 2; Iloprost; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Microscopy, Confocal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitriles; Phosphorylation; Protein Processing, Post-Translational; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype | 2004 |
Possible involvement of p38 MAP kinase in prostaglandin E1-induced ALP activity in osteoblast-like cells.
Topics: Adenylyl Cyclases; Alkaline Phosphatase; Alprostadil; Animals; Bucladesine; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Imidazoles; Isoquinolines; Mice; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sulfonamides | 2004 |
Prostaglandin E2 induces IL-23 production in bone marrow-derived dendritic cells.
Topics: Alprostadil; Animals; Arthritis; Bone Marrow Cells; Bucladesine; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Cells, Cultured; Colforsin; Culture Media, Conditioned; Cyclic AMP; Dendritic Cells; Dinoprostone; Gene Expression Regulation; Inflammation; Interleukin-12; Interleukin-12 Subunit p35; Interleukin-12 Subunit p40; Interleukin-17; Interleukin-23; Interleukin-23 Subunit p19; Interleukins; Lipopolysaccharides; Male; Mice; Misoprostol; Plasmacytoma; Prostaglandin Antagonists; Protein Subunits; Receptors, Cell Surface; Second Messenger Systems; Specific Pathogen-Free Organisms; Toll-Like Receptor 2; Toll-Like Receptor 4 | 2004 |
Involvement of SAPK/JNK in prostaglandin E(1)-induced VEGF synthesis in osteoblast-like cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Anthracenes; Cell Line; Colforsin; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-jun; Pyridines; Vascular Endothelial Growth Factor A | 2004 |
Prostaglandin E2--mediated relaxation of the ductus arteriosus: effects of gestational age on g protein-coupled receptor expression, signaling, and vasomotor control.
Topics: 16,16-Dimethylprostaglandin E2; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylyl Cyclases; Alprostadil; Animals; Biphenyl Compounds; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Ductus Arteriosus; Enzyme Activation; Female; Gestational Age; Glyburide; Indomethacin; Isometric Contraction; NG-Nitroarginine Methyl Ester; Nitroprusside; Papio; Potassium Channels; Pregnancy; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sheep; Signal Transduction; Sodium Fluoride; Thionucleotides; Vasomotor System | 2004 |
Regulation of thrombomodulin expression in human vascular smooth muscle cells by COX-2-derived prostaglandins.
Topics: Alprostadil; Blood Coagulation; Bucladesine; Carotid Artery Diseases; Carotid Artery, Internal; Cells, Cultured; Colforsin; Coronary Vessels; Culture Media, Serum-Free; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Epoprostenol; Etoricoxib; Gene Expression Profiling; Gene Expression Regulation; Humans; Iloprost; Isoquinolines; Mammary Arteries; Membrane Proteins; Models, Biological; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyridines; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; RNA, Messenger; Saphenous Vein; Second Messenger Systems; Sulfonamides; Sulfones; Tetradecanoylphorbol Acetate; Thrombomodulin; Thrombophilia; Vasodilator Agents | 2005 |
Beta-adrenergic hyperresponsiveness in compensated hypothyroidism associated with Down syndrome.
Topics: Adenylyl Cyclases; Adolescent; Adult; Alprostadil; Child; Child, Preschool; Cholera Toxin; Colforsin; Cyclic AMP; Down Syndrome; Female; Gonadal Disorders; GTP-Binding Proteins; Humans; Hypothyroidism; Infant; Isoproterenol; Leukocytes, Mononuclear; Male; Receptors, Adrenergic, beta; Thyroid Hormones; Time Factors | 2005 |
Synthetic heteroprostanoids of A- and E-types as novel non-comprehensive inhibitors of adenylyl cyclase in rat hepatocytes.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Animals; Cell Membrane; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hepatocytes; Inhibitory Concentration 50; Male; Models, Chemical; Prostaglandins; Rats; Rats, Wistar | 2006 |
Ca2+ stimulation of adenylyl cyclase generates dynamic oscillations in cyclic AMP.
Topics: Adenylyl Cyclases; Alprostadil; Biological Clocks; Calcium; Calcium Channels; Calcium Signaling; Carbachol; Catalysis; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Isoproterenol; Time Factors | 2006 |
Biphasic regulation by bile acids of dermal fibroblast proliferation through regulation of cAMP production and COX-2 expression level.
Topics: Alprostadil; Bile Acids and Salts; Cell Proliferation; Chenodeoxycholic Acid; Colforsin; Cyclic AMP; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Fibroblasts; Forearm; Humans; Liver Diseases; Membrane Proteins; RNA, Messenger; Skin | 2006 |
Chloride transporting capability of Calu-3 epithelia following persistent knockdown of the cystic fibrosis transmembrane conductance regulator, CFTR.
Topics: Adenylyl Cyclases; Alprostadil; Carbachol; Cell Line; Chloride Channels; Chlorides; CLC-2 Chloride Channels; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial Cells; Fatty Acids; Genetic Vectors; Humans; Lubiprostone; Lung; Membrane Potentials; Muscarinic Agonists; Retroviridae; RNA Interference; RNA, Small Interfering; Time Factors | 2007 |
Tissue-specific mechanisms for CCN2/CTGF persistence in fibrotic gingiva: interactions between cAMP and MAPK signaling pathways, and prostaglandin E2-EP3 receptor mediated activation of the c-JUN N-terminal kinase.
Topics: Adult; Alprostadil; Cells, Cultured; Colforsin; Connective Tissue Growth Factor; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Fibrosis; Gene Expression Regulation; Gingiva; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Lung; MAP Kinase Signaling System; Mesangial Cells; Organ Specificity; p38 Mitogen-Activated Protein Kinases; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Transforming Growth Factor beta1 | 2007 |
Effects of prostaglandin E1 on vascular ATP-sensitive potassium channels.
Topics: Algorithms; Alprostadil; Analysis of Variance; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Glyburide; In Vitro Techniques; KATP Channels; Male; Patch-Clamp Techniques; Phenylephrine; Pinacidil; Protein Kinase Inhibitors; Rats; Rats, Wistar; Thionucleotides; Vasoconstriction; Vasodilation; Vasodilator Agents | 2007 |
Prostaglandin E1 inhibits IL-6-induced MCP-1 expression by interfering specifically in IL-6-dependent ERK1/2, but not STAT3, activation.
Topics: Alprostadil; Animals; Cells, Cultured; Chemokine CCL2; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Guanine Nucleotide Exchange Factors; Humans; Interleukin-6; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pertussis Toxin; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Substrate Specificity | 2008 |
Alpha2 adrenoreceptor agonist regulates protein kinase C-induced heat shock protein 27 phosphorylation in C6 glioma cells.
Topics: Adrenergic alpha-Agonists; Alprostadil; Analysis of Variance; Animals; Bucladesine; Cell Line, Tumor; Colforsin; Cyclic AMP; Dexmedetomidine; Dinoprostone; Drug Interactions; Gene Expression Regulation, Neoplastic; Glioma; Heat-Shock Proteins; Phorbol Esters; Phosphorylation; Protein Kinase C; Rats; Serine; Time Factors | 2008 |
Prostaglandin E2 reduces extracellular ATP-induced migration in cultured rat microglia.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Alprostadil; Animals; Animals, Newborn; Cell Movement; Cell Survival; Cells, Cultured; Colforsin; Dinoprostone; Enzyme Inhibitors; Extracellular Fluid; Microglia; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype | 2008 |
Phospholipase D activity in human platelets is inhibited by protein kinase A, involving inhibition of phospholipase D1 translocation.
Topics: Alprostadil; Blood Platelets; Colforsin; Cyclic AMP-Dependent Protein Kinases; Humans; Phospholipase D; Platelet Activation; Protein Transport; Thrombin | 2008 |
Prostaglandin receptor EP2 protects dopaminergic neurons against 6-OHDA-mediated low oxidative stress.
Topics: Adrenergic Agents; Alprostadil; Animals; Cells, Cultured; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Humans; Mesencephalon; Neurons; Oxidative Stress; Oxidopamine; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Substantia Nigra; Tyrosine 3-Monooxygenase | 2008 |
Altered hippocampal long-term synaptic plasticity in mice deficient in the PGE2 EP2 receptor.
Topics: Alprostadil; Animals; Animals, Newborn; Colforsin; Cyclooxygenase Inhibitors; Dinoprostone; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Maze Learning; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neurons; Nitrobenzenes; Patch-Clamp Techniques; Physical Phenomena; Reaction Time; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Sulfonamides; Synapses; Time Factors | 2009 |
Regulation of Nur77 gene expression by prostanoids in cementoblastic cells.
Topics: Alprostadil; Animals; Calcium Signaling; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dental Cementum; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression Regulation; Mice; Misoprostol; Nuclear Receptor Subfamily 4, Group A, Member 1; Prostaglandins; Prostaglandins F, Synthetic; Protein Kinase C; Receptors, Prostaglandin; Receptors, Prostaglandin E; Signal Transduction; Time Factors | 2009 |
Activation of intestinal Cl- secretion by lubiprostone requires the cystic fibrosis transmembrane conductance regulator.
Topics: Adult; Alprostadil; Animals; Carbachol; Cell Line, Tumor; Child; Chloride Channels; Chlorides; Colforsin; Colon; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Humans; Ileum; Intestinal Mucosa; Ion Transport; Lubiprostone; Membrane Potentials; Mice; Mice, Knockout; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Tumor Cells, Cultured | 2009 |
Prostaglandin E2-induced colonic secretion in patients with and without colorectal neoplasia.
Topics: Alprostadil; Biopsy; Bumetanide; Colforsin; Colon; Colorectal Neoplasms; Dinoprostone; Female; Humans; Ion Transport; Lubiprostone; Male; Middle Aged; Ouabain; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin E; Reference Values; Signal Transduction; Tamoxifen; Theophylline | 2010 |
Fibroblast-specific expression of AC6 enhances beta-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis.
Topics: Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Alprostadil; Animals; Bleomycin; Calcium-Binding Proteins; Catecholamines; Colforsin; Collagen; Cyclic AMP; Epoprostenol; Fibroblasts; Isoproterenol; Lung; Membrane Microdomains; Mice; Mice, Transgenic; Pulmonary Fibrosis; Rats; S100 Calcium-Binding Protein A4; S100 Proteins; Signal Transduction | 2010 |
Lubiprostone activates Cl- secretion via cAMP signaling and increases membrane CFTR in the human colon carcinoma cell line, T84.
Topics: Alprostadil; Benzoates; Biological Transport; Bumetanide; Carcinoma; Cathartics; Cell Line, Tumor; Cell Membrane; Chlorides; Colforsin; Colonic Neoplasms; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Lubiprostone; Thiazolidines | 2011 |
Cyclic AMP control measured in two compartments in HEK293 cells: phosphodiesterase K(M) is more important than phosphodiesterase localization.
Topics: Alprostadil; Bioluminescence Resonance Energy Transfer Techniques; Biosensing Techniques; Cell Compartmentation; Cell Membrane; Colforsin; Cyclic AMP; Cytosol; HEK293 Cells; Humans; Kinetics; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Transport; Subcellular Fractions | 2011 |
Adenylyl cyclase 2 selectively couples to E prostanoid type 2 receptors, whereas adenylyl cyclase 3 is not receptor-regulated in airway smooth muscle.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Bronchi; Caveolins; Cell Line, Transformed; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; HEK293 Cells; Humans; Isoproterenol; Male; Mice; Muscle, Smooth; Myocytes, Smooth Muscle; Receptors, Adrenergic, beta-2; Receptors, G-Protein-Coupled; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction | 2012 |
Methadone but not morphine inhibits lubiprostone-stimulated Cl- currents in T84 intestinal cells and recombinant human ClC-2, but not CFTR Cl- currents.
Topics: Alprostadil; Biological Transport; Cadmium Chloride; Chloride Channels; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Lubiprostone; Methadone; Morphine; Naloxone; Patch-Clamp Techniques; Recombinant Proteins; Time Factors; Transfection | 2013 |
Inactivation of the Carney complex gene 1 (PRKAR1A) alters spatiotemporal regulation of cAMP and cAMP-dependent protein kinase: a study using genetically encoded FRET-based reporters.
Topics: Alprostadil; Carney Complex; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Gene Silencing; HEK293 Cells; Humans; Intracellular Space; Protein Transport; RNA Interference; Signal Transduction | 2014 |
Neuroprotective role of prostaglandin PGE2 EP2 receptor in hemin-mediated toxicity.
Topics: Adjuvants, Immunologic; Alprostadil; Analysis of Variance; Animals; Animals, Newborn; Cell Survival; Cerebral Cortex; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Hemin; L-Lactate Dehydrogenase; Mice; Mice, Knockout; Neurons; Neuroprotective Agents; Receptors, Prostaglandin E, EP2 Subtype; Thionucleotides | 2015 |
cAMP signaling primes lung endothelial cells to activate caspase-1 during
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Alprostadil; Animals; Caspase 1; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Endothelial Cells; Gene Expression Regulation; Host-Pathogen Interactions; Inflammasomes; Interleukin-1beta; Lung; Primary Cell Culture; Pseudomonas aeruginosa; Rats; Rolipram; Signal Transduction; Single-Cell Analysis | 2020 |